LOCUS       DAVDHC010000001       132621 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVDHC010000001 DAVDHC010000000
VERSION     DAVDHC010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 132621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 132621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..132621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.001"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(127..1062)
                     /locus_tag="VUR43_000001"
     CDS             complement(127..1062)
                     /locus_tag="VUR43_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET5411761.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAGSLFKATAPITRNELIIEIWRTFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GFAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1059..1919)
                     /locus_tag="VUR43_000002"
     CDS             complement(1059..1919)
                     /locus_tag="VUR43_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET5411762.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2027..4189
                     /locus_tag="VUR43_000003"
     CDS             2027..4189
                     /locus_tag="VUR43_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET5411763.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLEHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQFLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKNLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4281..5540
                     /locus_tag="VUR43_000004"
     CDS             4281..5540
                     /locus_tag="VUR43_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5411764.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5554..6420
                     /locus_tag="VUR43_000005"
     CDS             5554..6420
                     /locus_tag="VUR43_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5411765.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6434..7267
                     /locus_tag="VUR43_000006"
     CDS             6434..7267
                     /locus_tag="VUR43_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5411766.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7578..9020
                     /gene="gtfA"
                     /locus_tag="VUR43_000007"
     CDS             7578..9020
                     /gene="gtfA"
                     /locus_tag="VUR43_000007"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET5411767.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9158..10351
                     /locus_tag="VUR43_000008"
     CDS             9158..10351
                     /locus_tag="VUR43_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET5411768.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11038..13017
                     /locus_tag="VUR43_000009"
     CDS             11038..13017
                     /locus_tag="VUR43_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5411769.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13084..14580
                     /locus_tag="VUR43_000010"
     CDS             13084..14580
                     /locus_tag="VUR43_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5411770.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14580..15506
                     /locus_tag="VUR43_000011"
     CDS             14580..15506
                     /locus_tag="VUR43_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5411771.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15515..16582
                     /locus_tag="VUR43_000012"
     CDS             15515..16582
                     /locus_tag="VUR43_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411772.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16593..17519
                     /locus_tag="VUR43_000013"
     CDS             16593..17519
                     /locus_tag="VUR43_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411773.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17594..18920)
                     /locus_tag="VUR43_000014"
                     /pseudo
     CDS             complement(17594..18920)
                     /locus_tag="VUR43_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(19075..19785)
                     /gene="treR"
                     /locus_tag="VUR43_000015"
     CDS             complement(19075..19785)
                     /gene="treR"
                     /locus_tag="VUR43_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET5411774.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            19970..21937
                     /gene="treP"
                     /locus_tag="VUR43_000016"
     CDS             19970..21937
                     /gene="treP"
                     /locus_tag="VUR43_000016"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET5411775.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            22115..23740
                     /gene="treC"
                     /locus_tag="VUR43_000017"
     CDS             22115..23740
                     /gene="treC"
                     /locus_tag="VUR43_000017"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET5411776.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            23996..24244
                     /locus_tag="VUR43_000018"
     CDS             23996..24244
                     /locus_tag="VUR43_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET5411777.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            24451..25245
                     /gene="racE"
                     /locus_tag="VUR43_000019"
     CDS             24451..25245
                     /gene="racE"
                     /locus_tag="VUR43_000019"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET5411778.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            25242..26213
                     /locus_tag="VUR43_000020"
     CDS             25242..26213
                     /locus_tag="VUR43_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET5411779.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            26189..26710
                     /locus_tag="VUR43_000021"
     CDS             26189..26710
                     /locus_tag="VUR43_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET5411780.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            26707..27168
                     /locus_tag="VUR43_000022"
     CDS             26707..27168
                     /locus_tag="VUR43_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET5411781.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            27159..27899
                     /gene="xerD"
                     /locus_tag="VUR43_000023"
     CDS             27159..27899
                     /gene="xerD"
                     /locus_tag="VUR43_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET5411782.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            27899..28627
                     /locus_tag="VUR43_000024"
     CDS             27899..28627
                     /locus_tag="VUR43_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET5411783.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            28646..29215
                     /locus_tag="VUR43_000025"
     CDS             28646..29215
                     /locus_tag="VUR43_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET5411784.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            29202..29924
                     /locus_tag="VUR43_000026"
     CDS             29202..29924
                     /locus_tag="VUR43_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET5411785.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            29924..30166
                     /gene="yidD"
                     /locus_tag="VUR43_000027"
     CDS             29924..30166
                     /gene="yidD"
                     /locus_tag="VUR43_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET5411786.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(30391..31356)
                     /locus_tag="VUR43_000028"
     CDS             complement(30391..31356)
                     /locus_tag="VUR43_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5411787.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(31452..32204)
                     /locus_tag="VUR43_000029"
     CDS             complement(31452..32204)
                     /locus_tag="VUR43_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411788.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(32201..33157)
                     /locus_tag="VUR43_000030"
     CDS             complement(32201..33157)
                     /locus_tag="VUR43_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET5411789.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(33147..34106)
                     /locus_tag="VUR43_000031"
     CDS             complement(33147..34106)
                     /locus_tag="VUR43_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5411790.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(34403..34513)
                     /locus_tag="VUR43_000032"
     CDS             complement(34403..34513)
                     /locus_tag="VUR43_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HET5411791.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            complement(34529..35230)
                     /locus_tag="VUR43_000033"
     CDS             complement(34529..35230)
                     /locus_tag="VUR43_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HET5411792.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRATVD
                     NRASFKELDVYDASALKAYLEENQIDAVLHYAGEIVVSESIENPSKYFTANVAGRDQV
                     LKVLSEVGTQKIMFSSTASLYGNNCIDKPATEDTLIDPVNPYTETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            35631..36695
                     /gene="pepA"
                     /locus_tag="VUR43_000034"
     CDS             35631..36695
                     /gene="pepA"
                     /locus_tag="VUR43_000034"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET5411793.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            36717..37013
                     /locus_tag="VUR43_000035"
     CDS             36717..37013
                     /locus_tag="VUR43_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET5411794.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            37695..38138
                     /locus_tag="VUR43_000036"
     CDS             37695..38138
                     /locus_tag="VUR43_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5411795.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            38142..38906
                     /locus_tag="VUR43_000037"
     CDS             38142..38906
                     /locus_tag="VUR43_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET5411796.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            38921..39649
                     /locus_tag="VUR43_000038"
     CDS             38921..39649
                     /locus_tag="VUR43_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411797.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            39642..41162
                     /locus_tag="VUR43_000039"
     CDS             39642..41162
                     /locus_tag="VUR43_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET5411798.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            41507..42313
                     /locus_tag="VUR43_000040"
     CDS             41507..42313
                     /locus_tag="VUR43_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET5411799.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSETMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(42480..43016)
                     /locus_tag="VUR43_000041"
     CDS             complement(42480..43016)
                     /locus_tag="VUR43_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET5411800.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLQRELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            43149..44039
                     /locus_tag="VUR43_000042"
     CDS             43149..44039
                     /locus_tag="VUR43_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET5411801.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGIFGSSAVLADSVHDLVDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     VSLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            44283..44636
                     /locus_tag="VUR43_000043"
     CDS             44283..44636
                     /locus_tag="VUR43_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET5411802.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            44637..45674
                     /locus_tag="VUR43_000044"
     CDS             44637..45674
                     /locus_tag="VUR43_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET5411803.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAVTTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(45720..46727)
                     /gene="galR"
                     /locus_tag="VUR43_000045"
     CDS             complement(45720..46727)
                     /gene="galR"
                     /locus_tag="VUR43_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET5411804.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            46892..48070
                     /locus_tag="VUR43_000046"
     CDS             46892..48070
                     /locus_tag="VUR43_000046"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET5411805.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            48089..49570
                     /locus_tag="VUR43_000047"
     CDS             48089..49570
                     /locus_tag="VUR43_000047"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET5411806.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQAAFMRFVEQVGISLD"
     gene            49640..50044
                     /locus_tag="VUR43_000048"
     CDS             49640..50044
                     /locus_tag="VUR43_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET5411807.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGRRSEDRQVRI"
     gene            50201..51055
                     /locus_tag="VUR43_000049"
     CDS             50201..51055
                     /locus_tag="VUR43_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET5411808.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            51081..51851
                     /locus_tag="VUR43_000050"
     CDS             51081..51851
                     /locus_tag="VUR43_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET5411809.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            51838..52704
                     /locus_tag="VUR43_000051"
     CDS             51838..52704
                     /locus_tag="VUR43_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnII"
                     /protein_id="HET5411810.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(52791..54053)
                     /locus_tag="VUR43_000052"
     CDS             complement(52791..54053)
                     /locus_tag="VUR43_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET5411811.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVSSLLAIVLNAVLNHKKK"
     gene            complement(54053..54634)
                     /locus_tag="VUR43_000053"
     CDS             complement(54053..54634)
                     /locus_tag="VUR43_000053"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET5411812.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(55034..55129)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(55513..55752)
                     /locus_tag="VUR43_000054"
     CDS             complement(55513..55752)
                     /locus_tag="VUR43_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET5411813.1"
                     /translation="MLEEGTKDQLAELTYLFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDHYIYPHEFAVLDPDSYFLRFSE"
     gene            complement(55752..55895)
                     /locus_tag="VUR43_000055"
     CDS             complement(55752..55895)
                     /locus_tag="VUR43_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET5411814.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCDLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            complement(55907..56734)
                     /gene="xth"
                     /locus_tag="VUR43_000056"
     CDS             complement(55907..56734)
                     /gene="xth"
                     /locus_tag="VUR43_000056"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET5411815.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            56867..57322
                     /locus_tag="VUR43_000057"
                     /pseudo
     CDS             56867..57322
                     /locus_tag="VUR43_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            57475..57771
                     /locus_tag="VUR43_000058"
     CDS             57475..57771
                     /locus_tag="VUR43_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET5411816.1"
                     /translation="MSASDVALKLRGQGIFQMKQVKRAVQEQNGQLIVVQMGDENSKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            57977..59722
                     /locus_tag="VUR43_000059"
     CDS             57977..59722
                     /locus_tag="VUR43_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5411817.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     CLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            59712..61463
                     /locus_tag="VUR43_000060"
     CDS             59712..61463
                     /locus_tag="VUR43_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411818.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGLSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            61636..62328
                     /locus_tag="VUR43_000061"
     CDS             61636..62328
                     /locus_tag="VUR43_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET5411819.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMHYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            62371..63597
                     /locus_tag="VUR43_000062"
     CDS             62371..63597
                     /locus_tag="VUR43_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET5411820.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWRANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            64728..66887
                     /gene="pfbA"
                     /locus_tag="VUR43_000063"
     CDS             64728..66887
                     /gene="pfbA"
                     /locus_tag="VUR43_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET5411821.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNN
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            66871..67167
                     /locus_tag="VUR43_000064"
     CDS             66871..67167
                     /locus_tag="VUR43_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5411822.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            67403..67719
                     /locus_tag="VUR43_000065"
                     /pseudo
     CDS             67403..67719
                     /locus_tag="VUR43_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            67899..68558
                     /locus_tag="VUR43_000066"
     CDS             67899..68558
                     /locus_tag="VUR43_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET5411823.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            68583..69650
                     /locus_tag="VUR43_000067"
     CDS             68583..69650
                     /locus_tag="VUR43_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5411824.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            69753..70763
                     /locus_tag="VUR43_000068"
     CDS             69753..70763
                     /locus_tag="VUR43_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411825.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            70775..72466
                     /locus_tag="VUR43_000069"
     CDS             70775..72466
                     /locus_tag="VUR43_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET5411826.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            72469..73179
                     /locus_tag="VUR43_000070"
     CDS             72469..73179
                     /locus_tag="VUR43_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET5411827.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            73275..73466
                     /locus_tag="VUR43_000071"
     CDS             73275..73466
                     /locus_tag="VUR43_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5411828.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            73751..74752
                     /locus_tag="VUR43_000072"
     CDS             73751..74752
                     /locus_tag="VUR43_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5411829.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            75360..75437
                     /locus_tag="VUR43_000073"
                     /pseudo
     CDS             75360..75437
                     /locus_tag="VUR43_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            75938..77299
                     /gene="trpE"
                     /locus_tag="VUR43_000074"
     CDS             75938..77299
                     /gene="trpE"
                     /locus_tag="VUR43_000074"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET5411830.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYIVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            77296..77862
                     /locus_tag="VUR43_000075"
     CDS             77296..77862
                     /locus_tag="VUR43_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET5411831.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            77873..78877
                     /gene="trpD"
                     /locus_tag="VUR43_000076"
     CDS             77873..78877
                     /gene="trpD"
                     /locus_tag="VUR43_000076"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET5411832.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            78874..79641
                     /gene="trpC"
                     /locus_tag="VUR43_000077"
     CDS             78874..79641
                     /gene="trpC"
                     /locus_tag="VUR43_000077"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET5411833.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTR
                     QDAERLAPYFNGILVGTALMQAENVVQRIKELQIDKG"
     gene            79628..80227
                     /locus_tag="VUR43_000078"
     CDS             79628..80227
                     /locus_tag="VUR43_000078"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET5411834.1"
                     /translation="MTKVKICGLSTEEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPSDVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            80205..81428
                     /gene="trpB"
                     /locus_tag="VUR43_000079"
     CDS             80205..81428
                     /gene="trpB"
                     /locus_tag="VUR43_000079"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET5411835.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            81421..82197
                     /locus_tag="VUR43_000080"
     CDS             81421..82197
                     /locus_tag="VUR43_000080"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET5411836.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(82169..82828)
                     /locus_tag="VUR43_000081"
     CDS             complement(82169..82828)
                     /locus_tag="VUR43_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET5411837.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSVSHCDSCQTRLR
                     PLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            82898..83344
                     /locus_tag="VUR43_000082"
     CDS             82898..83344
                     /locus_tag="VUR43_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5411838.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGFIQKIRLEDSNLHIGRFFINPQKQEQGLGSQALRKFVSLAFE
                     NEDIYSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSILKLE"
     gene            complement(83572..84750)
                     /locus_tag="VUR43_000083"
     CDS             complement(83572..84750)
                     /locus_tag="VUR43_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET5411839.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLISQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            85030..86292
                     /locus_tag="VUR43_000084"
     CDS             85030..86292
                     /locus_tag="VUR43_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5411840.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVSIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            86295..87191
                     /locus_tag="VUR43_000085"
     CDS             86295..87191
                     /locus_tag="VUR43_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET5411841.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKTVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            87206..87523
                     /locus_tag="VUR43_000086"
     CDS             87206..87523
                     /locus_tag="VUR43_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5411842.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            87540..87857
                     /locus_tag="VUR43_000087"
     CDS             87540..87857
                     /locus_tag="VUR43_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5411843.1"
                     /translation="MNESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            87867..89222
                     /locus_tag="VUR43_000088"
     CDS             87867..89222
                     /locus_tag="VUR43_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5411844.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSSVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            89545..91020
                     /locus_tag="VUR43_000089"
     CDS             89545..91020
                     /locus_tag="VUR43_000089"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET5411845.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDIYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            91017..91865
                     /locus_tag="VUR43_000090"
     CDS             91017..91865
                     /locus_tag="VUR43_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET5411846.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVSNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            91880..92650
                     /locus_tag="VUR43_000091"
     CDS             91880..92650
                     /locus_tag="VUR43_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET5411847.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMEMTLYNLFHIL"
     gene            complement(92911..93198)
                     /locus_tag="VUR43_000092"
     CDS             complement(92911..93198)
                     /locus_tag="VUR43_000092"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET5411848.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            93401..93673
                     /locus_tag="VUR43_000093"
                     /pseudo
     CDS             93401..93673
                     /locus_tag="VUR43_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(93783..93986)
                     /locus_tag="VUR43_000094"
     CDS             complement(93783..93986)
                     /locus_tag="VUR43_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET5411849.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(94017..94625)
                     /locus_tag="VUR43_000095"
     CDS             complement(94017..94625)
                     /locus_tag="VUR43_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET5411850.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(94664..94834)
                     /locus_tag="VUR43_000096"
     CDS             complement(94664..94834)
                     /locus_tag="VUR43_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET5411851.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(94846..95412)
                     /gene="amaP"
                     /locus_tag="VUR43_000097"
     CDS             complement(94846..95412)
                     /gene="amaP"
                     /locus_tag="VUR43_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET5411852.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(95496..95660)
                     /locus_tag="VUR43_000098"
     CDS             complement(95496..95660)
                     /locus_tag="VUR43_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET5411853.1"
                     /translation="MGIIANVFAGLVGASAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            96102..97583
                     /locus_tag="VUR43_000099"
     CDS             96102..97583
                     /locus_tag="VUR43_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5411854.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDVKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            97944..98945
                     /locus_tag="VUR43_000100"
     CDS             97944..98945
                     /locus_tag="VUR43_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5411855.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRCRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            99095..100012
                     /locus_tag="VUR43_000101"
     CDS             99095..100012
                     /locus_tag="VUR43_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5411856.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            100023..100913
                     /locus_tag="VUR43_000102"
     CDS             100023..100913
                     /locus_tag="VUR43_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5411857.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            100942..102558
                     /locus_tag="VUR43_000103"
     CDS             100942..102558
                     /locus_tag="VUR43_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5411858.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILNEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            102568..103887
                     /locus_tag="VUR43_000104"
     CDS             102568..103887
                     /locus_tag="VUR43_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET5411859.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKIEQNPVATGADLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(104095..104167)
                     /locus_tag="VUR43_000105"
     tRNA            complement(104095..104167)
                     /locus_tag="VUR43_000105"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(104132..104134),aa:Lys,seq:ctt)
     gene            complement(104432..105703)
                     /locus_tag="VUR43_000106"
     CDS             complement(104432..105703)
                     /locus_tag="VUR43_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET5411860.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     ITLSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            105973..106212
                     /locus_tag="VUR43_000107"
     CDS             105973..106212
                     /locus_tag="VUR43_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5411861.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            106377..106556
                     /locus_tag="VUR43_000108"
     CDS             106377..106556
                     /locus_tag="VUR43_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5411862.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            106693..106872
                     /locus_tag="VUR43_000109"
     CDS             106693..106872
                     /locus_tag="VUR43_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET5411863.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQVGL"
     gene            106909..107361
                     /locus_tag="VUR43_000110"
     CDS             106909..107361
                     /locus_tag="VUR43_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET5411864.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISDALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            107652..108122
                     /locus_tag="VUR43_000111"
     CDS             107652..108122
                     /locus_tag="VUR43_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET5411865.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLVYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            108178..108720
                     /locus_tag="VUR43_000112"
     CDS             108178..108720
                     /locus_tag="VUR43_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5411866.1"
                     /translation="MLEKVKQFFRSRSAKTEPSVDILPRNRFADLDFERVLKSGARRL
                     VNEEGRYAEDGKITELEFPEDFAEFEFLVGFKTEEEEQFQQLLARLNSIDNAIQSYLE
                     SEMQQPIPQYAKDLGYTQKRWEKTFYFHPWILSGEENPPNLRYVADYVNDEFTVYFAK
                     KHGRWQAYWDAECQKVIEES"
     gene            108770..109204
                     /locus_tag="VUR43_000113"
     CDS             108770..109204
                     /locus_tag="VUR43_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5411867.1"
                     /translation="MELLNSRMDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPG
                     GGREGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQF
                     DNIIFGDEGQGYKLMPIEEFLNSKQAVPQLQGRLRDYLEESL"
     gene            109201..109674
                     /locus_tag="VUR43_000114"
     CDS             109201..109674
                     /locus_tag="VUR43_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5411868.1"
                     /translation="MITLVRAGAEDLETIIAIQRASFKAVYEKYHDEYDPYLEDCERI
                     KWKLVERPNSYYYFVKEDEENIGFLRVQTNAELTKAWLGTAAILPQYQGKGYGSKGLS
                     LLEKEFPTITQWDLCTVLQDAGMVAFYEKNGYRKIHIEAEKEGMDMVYMKKLIEK"
     gene            109812..110762
                     /locus_tag="VUR43_000115"
     CDS             109812..110762
                     /locus_tag="VUR43_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET5411869.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPETVDVAAVEADLQARLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            110764..111507
                     /locus_tag="VUR43_000116"
     CDS             110764..111507
                     /locus_tag="VUR43_000116"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET5411870.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDSIIVAYEELAKEGEAAALLQAVTDLETGAKLLFIFGPEGGLSPVEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            111518..113314
                     /gene="pepF"
                     /locus_tag="VUR43_000117"
     CDS             111518..113314
                     /gene="pepF"
                     /locus_tag="VUR43_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET5411871.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(113374..114051)
                     /locus_tag="VUR43_000118"
     CDS             complement(113374..114051)
                     /locus_tag="VUR43_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5411872.1"
                     /translation="MEPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            114298..115068
                     /locus_tag="VUR43_000119"
     CDS             114298..115068
                     /locus_tag="VUR43_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411873.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGEGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFLGLTGTEKEDLHV"
     gene            115061..115825
                     /locus_tag="VUR43_000120"
     CDS             115061..115825
                     /locus_tag="VUR43_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5411874.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISILITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLAIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            116232..117023
                     /locus_tag="VUR43_000121"
     CDS             116232..117023
                     /locus_tag="VUR43_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET5411875.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     AKEIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALIYANLLSADANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHSFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFYKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            117134..117802
                     /locus_tag="VUR43_000122"
     CDS             117134..117802
                     /locus_tag="VUR43_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET5411876.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(117968..118045)
                     /locus_tag="VUR43_000123"
                     /pseudo
     CDS             complement(117968..118045)
                     /locus_tag="VUR43_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            118116..118772
                     /locus_tag="VUR43_000124"
     CDS             118116..118772
                     /locus_tag="VUR43_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET5411877.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTDLGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            118762..119085
                     /locus_tag="VUR43_000125"
     CDS             118762..119085
                     /locus_tag="VUR43_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET5411878.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            119189..120019
                     /locus_tag="VUR43_000126"
     CDS             119189..120019
                     /locus_tag="VUR43_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5411879.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            120173..121027
                     /locus_tag="VUR43_000127"
     CDS             120173..121027
                     /locus_tag="VUR43_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET5411880.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKSLFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            121127..122500
                     /locus_tag="VUR43_000128"
     CDS             121127..122500
                     /locus_tag="VUR43_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET5411881.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            122493..123554
                     /locus_tag="VUR43_000129"
     CDS             122493..123554
                     /locus_tag="VUR43_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET5411882.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            123556..124248
                     /locus_tag="VUR43_000130"
     CDS             123556..124248
                     /locus_tag="VUR43_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5411883.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(124278..124847)
                     /locus_tag="VUR43_000131"
     CDS             complement(124278..124847)
                     /locus_tag="VUR43_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET5411884.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            124982..125596
                     /locus_tag="VUR43_000132"
     CDS             124982..125596
                     /locus_tag="VUR43_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET5411885.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            125598..127244
                     /locus_tag="VUR43_000133"
     CDS             125598..127244
                     /locus_tag="VUR43_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5411886.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHQVSYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            127256..128542
                     /locus_tag="VUR43_000134"
     CDS             127256..128542
                     /locus_tag="VUR43_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5411887.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQIGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            128594..129127
                     /locus_tag="VUR43_000135"
     CDS             128594..129127
                     /locus_tag="VUR43_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5411888.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDETMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            129205..129675
                     /gene="nrdI"
                     /locus_tag="VUR43_000136"
     CDS             129205..129675
                     /gene="nrdI"
                     /locus_tag="VUR43_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET5411889.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(129968..131230)
                     /locus_tag="VUR43_000137"
     CDS             complement(129968..131230)
                     /locus_tag="VUR43_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET5411890.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(131540..131998)
                     /locus_tag="VUR43_000138"
     CDS             complement(131540..131998)
                     /locus_tag="VUR43_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET5411891.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(131995..132435)
                     /locus_tag="VUR43_000139"
     CDS             complement(131995..132435)
                     /locus_tag="VUR43_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5411892.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLIEIFLKNESFTYSSRRYLKTIKEKLEL"
BASE COUNT        39708 a        23368 c        29043 g        40502 t
ORIGIN      
        1 gttttaatga gagtttgtaa ctctcttttt tgtttttaga gacaataaaa cttcagatcc
       61 gtaaaactta attgaattac taatctgaag ttatttttat atcgtttata ttataattgt
      121 gttattttac ttccaactat tgagagaaat ttcgccacta tttagccaga tttcttttcc
      181 gttatcacat tgaactaaaa gttttccatt ttctgagatg tctttagcaa atcccttgta
      241 gtctttttgc tctagtgtga aagtgacttc ttttcctaga atgaatgact gttttttgta
      301 taggtataat agctcttctg ctggtgtttc gaagaaagta cgccagattt ctatgatcaa
      361 ttcattcctt gttataggag ctgtagcttt aaataagctg ccagcttttt cttttaattc
      421 ctgagggaag tctttaatag tgaaattgat acctactcca ataatgatat ctgtgactaa
      481 gccagtttct acagaggtca ttgcttcagt aaggattcct ccaattttat gattgtttag
      541 atagatatca ttgacccatt ttatgtcgac atctattaaa gttaggttct taatggcttt
      601 gtagacagct ccagctacaa gtagtgtgta ggatggtaat ttgtcatagg ggagatttgg
      661 tttaagatgg agtgtcatat aaataccacc ttgtggtgag tagaaggaac gttgaaaacg
      721 gcctcggcct gctgtttgat aggaagctag atagagggta tttgcttcat ggcctaaatc
      781 aattgcttct tttgcatcta gttgtgttga ttttgtttcg ggtttaaagc tgactttaat
      841 tggaagattt tcttctagaa tctctggaag aataaggtca ccattcatca gtttatatcc
      901 tctatttttg atactatcaa tttcaatgcc ttcttgttct agtcgcttga tggctttcca
      961 aattgatgtt cggcttaggg atagtttttc tgcgattttt tctccgctga tatagtcggt
     1021 ttctttagat aggatttggt agacagcttg gtaggatttc ataatgttgc ctttcttact
     1081 agttggtatt gagagtattc ttttcttgta tgacttggag tctgattaaa gtattgttta
     1141 taagctttcg aaaaatggag tggatctgaa aaacctaccg agtatgcaat taccttgatg
     1201 gactcttggg tattttcgag aagttgtcta gctcggtgca ttcgaacgta gagtaggtat
     1261 tctttgggtg ataaggtatt aaattctttg aatacgcttg ataagtagct tctgtgaacg
     1321 gatagttctt ttgctaaatc ttgaattgta agtgattgag gatagtggct atcaattaat
     1381 cgtttgcatt caagatagag ttggtgggtt gatgaaatat tctttttttt ctgattggga
     1441 gcaatagttc ccagatgaaa catcagttca tgaagttgtc ccatgatatg gagttgagct
     1501 aattcacttg attttgtaat ctgagcgaag cggacaatgt ctgagatgag ttttgcagta
     1561 gtctgggtat gacaagtttc agattggatg agataggatt gatcagaaat ttgagaaaga
     1621 gcaaaataat caggggattt ccctccagtg attcctaacc agtagtaggc ccaaggttct
     1681 ttactatctg cttgataaaa ggttagttcc tctggtttta atagaaagaa atctccttct
     1741 tttaaatcaa caattttacc cttgtaatga aattttcctt gtcctttagt aatgtaatgt
     1801 aggacgtatg tatcacgaat ggctggacca aaagagtaat taggtgtgca ttcctcatat
     1861 ccataaaagc ttagggcaag gtcgattgtt ccagtctggt attctgaaaa aactaacatg
     1921 tgctacctcc tacctaacat tttaccatat tcttgagaca tttttctatt ttagaaagcg
     1981 atttcaggtg ataaaatata atcaataaag tgatgaggtg aagtaaatgg gagttaggat
     2041 agagaataat ctattttatg ttgagagtaa aaatctaagt ttgattattg aaaatcgaaa
     2101 tggctactta cttttgaaac atttaggaaa gactattaag aactataaag gttccaatag
     2161 tgtttatgaa cgagaccatg ccttttcagg aaatccaaca gctactaatc gaacctttag
     2221 tttagatact caacgtcaaa tttttggaca acatggctta ggagatttta ggaaaccaac
     2281 catacaggtt cagcataatg taactgaagt aacagacttt cgatttgtag aagcaaagat
     2341 tttaaaaggt cagaatggtc cacagggctt accttctcca catagcatgg acgatacaga
     2401 gactcttgtc ttaatgttag aagattctaa ggctcaactt agtctgactt tgtattatac
     2461 tacttttaat aatgatgcga ctattgctag ctacagtaaa ttagataata atagtaatca
     2521 ggaagttgtc atctataaag atttttcttt tatggctgat tttccagctg cagattacga
     2581 aatagtaact ctgcagggtg cttatgctcg tgaaaagact gttagacgtc aacaggtaga
     2641 acaaggaatc ttttcgatta gttcaaaccg aggtgcttct ggtcatgctc aaacaccagc
     2701 tcttctacta tgcgaacaag gagtcacaga ggatgctggg aatgtgtttg ctattcaact
     2761 aatgtatagt ggcaactttg aagcttttgt tcaaaaaaat caattgaatg aagttcgggt
     2821 ggctattggc attaatccag aaaacttttc ttggaagtta gcccctgagg aatactttga
     2881 aacaccggta gctttagtga ctcattcaga tcagggatta actggtatta gtcatgaaag
     2941 tcagaatttt gtactggagc acattatgct aagtgaattt tctaaaaaag aacgtccaat
     3001 tctaatcaat aactgggaag ctacttactt tgactttcag agagaaaaac tgttagagtt
     3061 agcagatgaa gctaagaaag ttggcattga actttttgta ttagatgatg gttggtttgg
     3121 caatcgtttt gatgataatc gtgctttagg tgattgggtt gttaatgagg aaaaactggg
     3181 tggaagtcta gaaagtctga tttcagctat ccatgaaaga ggtttgcagt ttggactttg
     3241 gttagaaccc gaaatgattt ctgtagatag tgatttgtat cgtcaacatc ctgactgggc
     3301 tattcaggtt cctggctatg agcatactta ttctcggaat caattagtac ttaatcttgc
     3361 caatcctcag gtagtagaat acttgaaaag tgtcttagat caattcctat cttatcatga
     3421 tattgattac attaaatggg atatgaaccg caatatcact aagctaggga atggattaac
     3481 ttatctagag acacagatgc aatctcatca gtacatgctg gggctttacg aactcgtttc
     3541 ttatctgaca gagaagcaca gccatattct ctttgagtcc tgctctggtg gtggtggacg
     3601 aaatgatctt ggtatgatgc gctatttccc acaagtctgg gctagtgata atactgatgc
     3661 cattgcacgt ttaccaattc aatacggttc atcctatctc tatccaacca tttctatggg
     3721 ggctcatgtg tcagcagtac cgaatcatca gatgggacga atgacaccat tagaaacacg
     3781 tggccttgta gcaatgatgg gaaatttggg ctatgaactt gatttgacaa atttatcaga
     3841 tgaagagaaa gctacgattg ctaatcaggt gaacttgtat aaagaattac gaccagtagt
     3901 tcagttagga cagcagtata gactaattaa tcctgatact gtatccaatg aagcagctgt
     3961 acaatttaat tacggaaatc aaacgattgt aacctacgtt cgcgttttat ctgttgtaga
     4021 gaccatggaa acaactttaa aattaaaaaa tttggatgaa gagggactat ataaattaca
     4081 ggaaaatggc gaagtttact caggtgcaga actaatgtat gcgggcctaa ctgttatctt
     4141 atcccaagga gattttttga gtagacagta tatttttaga aaactatgat atgtactgac
     4201 ctcaaaagtt agatttattc tatctaactt ttgaggtgca gtttgataag ggtgtataaa
     4261 tttataaagg aggctttcta atggaatggt ataaaaaaat cggacttctt gcaactacag
     4321 gtttagcttt gtttgggctc ggtgcttgct ccaactatgg taaatctgcg gatgacacag
     4381 tgaccatcga gtatttcaac cagaaaaaag aaatgaccaa aaccttggaa gaaatcactc
     4441 gtgattttga gaaggaaaac cctaagataa aggtcaaagt cgtcaatgta ccaaatgctg
     4501 gtgaagtatt gaagacacgc gttctcgcag gagatgtgcc tgatgtggtc aatatttacc
     4561 cacagtccat cgaactgcaa gaatgggcaa aagcaggtgt ctttgaagat ttgagtaaca
     4621 aagactacct gaaacgcgtg aaaaatggct acgctgaaaa atatgctgta aacgaaaaag
     4681 tttacaacgt tccttttaca gctaatgctt atggaattta ctacaacaaa gataaattcg
     4741 aagaactggg cttgaaagtt cctgaaacct gggatgaatt tgaacagtta gtcaaagata
     4801 tcgttgctaa aggacaaaca ccatttggaa ttgcaggtgc agatgcttgg acactcaatg
     4861 gttacaatca attagccttt gcgacagcaa caggtggagg aaaagaagca aatcaatacc
     4921 ttcgttattc tcaaccaaat gccattaaat tgtcggatcc gattatgaaa gatgatatca
     4981 aggtcatgga catccttcgc atcaatggct ctaagcaaaa gaactgggaa ggtgctggct
     5041 ataccgatgt tatcggagcc ttcgcacgtg gggatgtcct catgacacca aatgggtctt
     5101 gggcgatcac agcgattaat gaacaaaaac cgaactttaa gattgggacc ttcatgattc
     5161 caggaaaaga aaaaggacaa agcttaaccg ttggtgcggg agacttggca tggtctatct
     5221 cagccaccac caaacatcca aaagaagcca atgcctttgt ggaatatatg acccgtccag
     5281 aagtcatgca aaaatactac gatgtggacg gatctccaac agcgatcgaa ggggtcaaac
     5341 aagcaggaga agattcaccg cttgctggta tgaccgaata tgcctttacg gatcgtcact
     5401 tggtctggtt gcaacaatac tggaccagtg aagcagactt ccataccttg accatgaact
     5461 atgtcttgac cggtgataaa caaggcatgg tcaatgattt gaatgccttc tttaacccga
     5521 tgaaagcgga tgtggattag gagtagagag actatgaaaa aagtattaca aaaatattgg
     5581 gcatgggctt ttgtggtcat ccccctcttg ttacaagcaa ttttcttcta tgtgccgatg
     5641 tttcaaggag ccttttacag ttttaccaac tggacaggat tgacttacaa ctacaaattt
     5701 gtcggcttaa acaactttaa gctcctcttc atggatccaa aattcatgaa tgcgattggc
     5761 tttaccgcaa tcattacgat tgccatggtg gttggtgaga ttgcactcgg gatcttcatt
     5821 gcgcgtgtct tgaactctaa aatcaaaggc caaaccttct tccgtgcttg gttcttcttc
     5881 ccagctgttt tatctggttt gacagtggct ttgatcttca agcaagtctt caactacggt
     5941 cttccagcga ttgggaatgc ccttcatatt gaatttctcc aaaccagtct tttagggact
     6001 aagtggggag caatctttgc ggctgtcttt gtccttcttt ggcaaggggt ggctatgccc
     6061 atcatcatct tcctagctgg tttgcaatct attccaactg agattacaga ggcagcaagg
     6121 attgatggtg cgactagcaa gcaagttttc tggaacattg aattgcctta cttgctacca
     6181 agtgtctcta tagtctttat cctagcccta aaaggtgggc tgactgcctt tgaccaagtc
     6241 tttgccatga ccggtggtgg tccaaacaat gccacaacct cacttgggct cttggtttat
     6301 aactatgcct ttaaaaacaa ccaattcggt tatgccaatg ccattgccgt aatcttgttc
     6361 ttcttaattg tagtgatttc gatcatccaa ttgagagtat ctaagaaatt tgaaatttaa
     6421 gaggagaagc atgatgaaac aagatgaaag aaaagccctg attggcaaat acattctatt
     6481 gattctagga tcggttctga ttttagtgcc gctccttgct accctcttta gttccttcaa
     6541 acccactaag gatattgtag ataatttctt tggctttcca accaacttca catgggacaa
     6601 ctttagccgt ctcttagctg atgggattgg aggctattat tggaactctg tcgtcatcac
     6661 tgtcttgtct ttacttgcag taatgatctt tatccctatg gcagcctact ccatcgctcg
     6721 caatatgagt aaaagaaaag cctttaccat catgtatacc ctcttaatcc tcggaatctt
     6781 cgtacctttc caagtcatca tgattccgat tacggttatg atgagtaaac tcggtttggc
     6841 taataccttt ggtttgatct tgctctactt gacctatgcg attccacaga ccctctttct
     6901 ctatgttggc tatatcaaaa tctcgattcc agaaagtctg gatgaagcag cagagatcga
     6961 tggggctaat caatttacaa cctatttccg catcatcttc ccaatgatga aaccgatgca
     7021 tgcgacaacc atgattatca atgccctttg gttctggaat gacttcatgt tgccactcct
     7081 tgtcttgaac cgggattcca aaatgtggac tctgcctttg ttccaataca actacgcagg
     7141 ccaatatttc aacgactacg gaccaagctt tgcctcttac gtggtcggca ttatcagtat
     7201 caccattgtc tatctcttct tccaacgcca tatcatttca ggaatgagca acggggcagt
     7261 gaagtaatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgtacttg
     7321 agtacggtaa ggtgaagctg acgtggtttg aagagatttt cgaatagtat aagaagagct
     7381 catggaatct atagtctttg acacagagga agagttcagc ttgttgataa ttctatgtag
     7441 aaaacaagaa agtagtactt tgtttatcac agtctatatt agtacgagtt tgatgataaa
     7501 tagagattta aaatgaattt tatttatgaa gccagatcat atgagacttg gcttcaatta
     7561 gaaaaaggag agtaatgatg ccaattcaaa ataaaaccat gttgattacc tattctgata
     7621 gccttggaaa taatcttaaa gacttatatg ataatttgga agagcatttt ggagatgcta
     7681 ttggaggagt tcacctttta ccatttttcc catcaacagg tgatcgtgga tttgcgccag
     7741 ttgactacga cgaagtggac tcagcttttg gtgattggga ggatgttaag cgtttaggtg
     7801 agagatatta tcttatgttt gattttatga ttaatcatat ttctcgtcaa tccaagtatt
     7861 ataaggacta tcaagaaaaa catgaagcca gtgaatttaa agatctcttt ttaaactggg
     7921 ataagttttg gccagaaaac cgtccgacac agtctgatgt agatttaatt tacaagcgta
     7981 aggatcgtgc accaaagcaa gagattgtgt ttgaagatgg ttcagtggaa catttgtgga
     8041 atacctttgg tgaggagcag attgatcttg atgtgaccaa agaagtaact atggaattta
     8101 tccgtaagac cattcagcac ttggcaagta atgggtgtga tttgattcgt ctagatgcct
     8161 ttgcttatgc agtgaagaaa ttggatacta atgatttctt tgtggaacca gatatttggg
     8221 atttattgga caaagttcga gatatcgctg ctgagtatgg gacagagctt ttacctgaga
     8281 ttcatgaaca ctattcgatt cagtttaaaa tagcagacca tgattactat gtttatgatt
     8341 ttgctcttcc aatggtgaca ctttatactc tttacagttc cagaacagag cgtttggcta
     8401 agtggttaaa gatgagcccg atgaagcaat ttacgacgct agatacccat gatgggattg
     8461 gagtagtaga tgtcaaggat atcctgaccg atgaggagat tgactatgct tcaaatgaac
     8521 tctataaggt tggagccaat gtcaaacgta agtactctag tgccgagtat aacaacttag
     8581 atatctacca aatcaattca acctactatt cagcgcttgg agatgatgat gtcaagtatt
     8641 ttctcgctcg tctaattcaa gcttttgccc caggtattcc tcaggtttac tatgtgggtc
     8701 tattagcagg caagaatgac ttgaaattat tagaagaaac taaagaaggt cgaaatatta
     8761 atcgtcatta ctatagcaac gaggaaatag caaaagaagt gcaacgacct gttgtgaagg
     8821 cccttctcaa tctattttct ttccgtaacc gttcagaagc ctttgatcta gaagggacta
     8881 ctgagataga gacaccaaca gctcacagca ttgtaatcaa acgtcaaaat aaagataagt
     8941 ccgtaacagc agtagcagaa attgatttgc aaaatcagac ttatcgggta attgagaatg
     9001 gagttgaagt aacattttga agccttgata tggtggataa aatagggttt ttattttgga
     9061 aaacgtttcc tttgttttca aattgctaaa aaagtggtac aatataggat agcttactat
     9121 tatctgaatc agctgatttg gagagaaagg attcattttg aaatcaatag gctttattga
     9181 aaagctgaag gggttgtcta gtaaagagct gattttattg ggaattatcc taagtatctt
     9241 tttacccttt tatctttttg tagttgtact ctgtttatat attatcagtt tgatttttac
     9301 aggagacatg aaaagtattc ttcagaaaat gggggagcat ccgatgctgc ttctttttct
     9361 tagctatagt actgttatat ccattcttgc acaaaattgg atgggtcttg tggcttcagt
     9421 aggaatgttt ctatttacta ttttcttttt gcactatcag tcgattttat cccataaatt
     9481 ctttcgattg attttgcagt tcgtcttgtt tggtagtgtc ttgtcagctg cttttgccag
     9541 tttagaacat ttccaaattg tgaagaaatt taactatgct tttctttcac ccaatatgca
     9601 ggtgtggcat cagaaccggg cagaagtgac cttctttaat cctaattatt atggaattat
     9661 ttgttgtttc tgtattatga ttgctttcta tctgtttaca acgaccaagt tgaattggtt
     9721 gaaagtattc tgtgtgattg caggctttgt taatctcttt ggtttgaact ttactcaaaa
     9781 tcgaactgcc tttcctgcta ttatcgctgg agcaattatc tatctcttta cgactattaa
     9841 aaactggaag gccttttggc ttagtattgg ggtcttcgcg attggtttga gtttcctctt
     9901 ttctagtgat ttgggagttc gaatgggtac tttagactct tctatggaag aacgcatttc
     9961 tatctgggat gctgggatgg ccttgtttaa gcaaaatcct ttttggggtg aagggccatt
    10021 gacctatatg cactcttatc ctcggataca tgctccttat catgaacatg cccacagtct
    10081 ttatattgat acgattctga gttacggaat tgtgggtacc attttattag ttctgtcttc
    10141 tgttgctcct gttcgcttga tgatggatat gagtcaggag tcggggaaac gtccgattat
    10201 cggcctttat ctatctttcc ttacagtggt tgctgtgcac ggaatttttg acttggctct
    10261 cttctggatt cagtcaggct ttattttctt gctagttatg tgcagtattc cattggagca
    10321 tcgaatgttg gtatcggaca tgacggatta agttttataa gtttgaaatc ttctaccttg
    10381 ggtaggagat ttttttatac gatgggcatg tcgtggatct gaggtgtaag tcctctgtag
    10441 ggatccacta ccggtgaata caatagcgct ccccaagcct gactatcgtg aggtagcgga
    10501 ttaaaatggt ctggggatag atcgttttaa gtctgacgca ggaaataaga attgtcagag
    10561 aaagcaatag tgaaatcgta ggctatgaat agaaacgtga tagcgaggag catatagtgg
    10621 acaaggtagc gagaaatttt aaagtataaa agatagtctt aatctatatg tgtaaatcac
    10681 gaaagtaatt gaattcggaa taaggttggt gtgaaaagac atagtaaact gaatcttgaa
    10741 tactagaatg atacttctac aatattgtta taatttaatt tgaattccaa aatcacattg
    10801 ttccgtccgt atttcatttt actgtatgtc ttcctaagct ccaaaatttc tgtgtcaaat
    10861 ttcctatttt cactgtagtc tttgacactt cgaacgacaa tttgaatcat atattcaaaa
    10921 aaaaatgaaa aatttgtgcc aacaagccta aatattctga aaatttgttt gatttttaat
    10981 ggataatgtg atataatggt tgtcaatcta taattcacat aaacagagga gtagaaaatg
    11041 aaaaaaaatc gtgtatttgc tacagcaggt cttgttttat tagcagcagg tgtacttgca
    11101 gcatgcagtt cttcaaaatc atctgattca tcagccccta aagcttatgg ctatgtttat
    11161 acagcagacc cagaaacctt ggactacctg atttcaagta aaaatagtac aacagtagtg
    11221 acttcaaatg ggattgatgg tttattcact aacgataatt acggtaatct tgctcctgca
    11281 gttgcagagg attgggaagt ctctaaggat ggtttgacct acacttataa gattcgtaaa
    11341 ggggttaaat ggtttacctc tgatggagaa gaatatgcag aggtgacggc taaagatttc
    11401 gtgaacggtt taaaacacgc agcagataaa aaatcagaag ctatgtattt agctgaaaat
    11461 tcggttaaag gcttggcaga ttatctatca ggaacttcaa cagatttttc aacagttggt
    11521 gtcaaggcgg ttgatgatta tacgttacaa tacactttga accagcctga accgttctgg
    11581 aactctaagt tgacctattc tattttctgg cctctgaatg aagaattcga aacatcaaaa
    11641 ggaagcgatt ttgctaaacc aacagatccg acatccttgc tttataatgg tccattcttg
    11701 ttgaaagggt tgactgcaaa atcttctgta gagtttgtaa aaaatgagca atattgggat
    11761 aaagaaaatg tccacctaga tactatcaat ctagcttact atgatggatc agatcaggag
    11821 tcgctagagc gtaacttcac tagtggagct tatagttatg cccgtcttta ccctaccagc
    11881 tccaactatt ctaaggttgc agaagaatac aaggacaata tctattacac acaatcaggc
    11941 tctgggattg ctggtctggg tgtgaatatt gatcgccaaa gttacaacta tacctctaaa
    12001 actacagatt cagagaaagt agctactaag aaggcattgc ttaacaaaga tttccgtcaa
    12061 gccttgaatt ttgctcttga tcgctcagct tactcagctc aaatcaatgg taaagatgga
    12121 gcagctttag cagttcgtaa tttatttgta aaaccagact ttgtttcagc tggtgagaag
    12181 acctttggtg atttagtcgc tgctcaactt cctgcttatg gtgatgagtg gaaaggtgtg
    12241 aatttagctg atgggcagga tggtttattc aatgctgaca aggccaaggc agagtttgcg
    12301 aaagctaaga aagctttaga agcagacggc gttcagtttc ctattcatct ggacgttcca
    12361 gtagaccaag catcaaaaaa ctacatatct cgtattcagt cttttaaaca atctgtagaa
    12421 acagttcttg gtgttgaaaa tgtcgttgtt gatattcaac aaatgacaag tgatgaattc
    12481 cttaatatta cttactatgc tgccaatgct tcatctgagg attgggatgt atcaggagga
    12541 gtttcatggg gtccagacta tcaagaccca tctacttacc tggatatttt aaaaacaact
    12601 agcagtgaaa ctacaaaaac atatttagga tttgataatc caaatagccc ttcagtagtt
    12661 caagttggtt tgaaagaata cgataaatta gttgatgaag ctgccagaga gacaagcgac
    12721 ttgaatgtcc gttatgaaaa atatgcagcg gctcaagcat ggttgacaga tagttcactc
    12781 tttattcctg ctatggcttc ttctggtgca gcaccagtgc tttcacgaat tgttccattt
    12841 actggagctt ctgcgcaaac aggctctaag gggtcagatg tttacttcaa atatttgaaa
    12901 ttacaagata aagtggtgac taaggaagag tatgaaaaag ctcgtgaaaa atggttgaaa
    12961 gaaaaagctg aatcaaatga gaaagctcaa aaagaattgg caagtcatgt gaagtaaata
    13021 atttctaata gaactttctc tccatgagga gaaggttctt ttgggatttt taaaggaaat
    13081 aatatgaaaa aatatatttt tatgcgtgtt ttgcggtcat tggtttcgat tttcttagta
    13141 acgactttga cctacacgat tatctatacc ttggttcctc gaaaattgat tttcaagcag
    13201 gatcctaact ataataaaat tgcgacaacg gctgataaac gtgataacta tgaaaatact
    13261 gtgtttgagc gtatgggcta cattgagtat tacgatacta aagagttgca agaaaaggca
    13321 agtagcatgg attcttctgt aacagtagaa gcaaatgcga ccaataaagc tatttatgaa
    13381 aagtacatca atcaattagg tcatggttgg actttgggag aatttactga aagtggtcaa
    13441 ttctatgcta ctcgtgaaat tccaattttt gaacgtgttt ttcacttcta tgctaacttg
    13501 attgacattg accatacaaa taaaatccaa gaccctgaaa atccagactt gaaacgctac
    13561 cttcgttttg aaaatgatcc agctatcgga tggtcattgg tcggttcagg aactaaacat
    13621 aaatatctct tgtactttaa cagtcagttc ccatttgttc atcaaaactt tgtgaacttg
    13681 aatttaggtg actcttaccc aacctatgct aatacaccag ttcttcaggt tattactcaa
    13741 ggtcaaggac aaaccaaaac tgcccaagtt cagttcccaa caggtaagaa aacgtcttct
    13801 gtaaatattt actcaagaac ctacaagtca cctagtcagg ctgactctcg tgaagtagct
    13861 agctatggga aagatgatcc ttatacagcg actgaaagta attaccaata tccatctatg
    13921 attgtcagct ctgctattac tggtttgatt ggtttggttc ttgcctatgc tcttgccgtg
    13981 ccacttggtt cagccatggc tcgtttcaag aacacttgga ttgatagcct ctcaacaggg
    14041 actttgacct tcttgcttgc tcttccaacg attgccttgg tttacatcgt tcgattgatt
    14101 ggatcatcta ttgcccttcc agattcattc cctatcttgg gagctggaga ttggcgttct
    14161 tacgttttac cagcagtcat ccttggtttg ttgggtgctc ctgttacagc catttggatt
    14221 cgtcgttaca tgattgactt gcaatctcaa gactttgttc gtttcgctcg tgcaaaaggt
    14281 ttgtctgaaa aagaaatttc aaacaaacac atctttaaaa atgccatggt tccgctggtt
    14341 tcaggaattc ctggtgccat tattggggtt atcggtggtg caacccttac tgaaacagtc
    14401 ttcgccttcc caggtatggg taaaatgttg attgactctg taaaagcatc taataactct
    14461 atggtcgttg gtcttgtctt catctttaca tgtatttcta tcttctcacg tcttttggga
    14521 gatatttgga tgactattat tgacccacgt attaaattga ctgagaaagg aggcaaataa
    14581 tgtctacaat cgataaagaa aaatttcagt ttgtaaaacg tgacgatttt gcctctgaaa
    14641 ctattgatgc gccagcatat tcttactgga aatcagtgtt taaacaattt atgaagaaaa
    14701 aatcaactgt agtcatgttg ggaatcttgg tagccatcat tttgataagt ttcatctacc
    14761 caatgttttc taagtttgat ttcaatgatg tcagcaaggt aaacgacttt agtgttcgtt
    14821 atatcaagcc aaatgcggag cattggttcg gtactgacag taacggtaaa tcgctctttg
    14881 acggtgtctg gttcggagct cgtaactcca tcctcatttc tgtgattgcg acagtgatta
    14941 acttggttat cggtgttttt gtcggtggta tttggggtat ttcaaaatca gttgaccgtg
    15001 tcatgatgga agtttacaac gtcatctcaa acatcccacc tcttttgatt gttattgtct
    15061 tgacttactc aatcggagct ggattctgga atctgatttt tgccatgagc gtaacaacat
    15121 ggattggtat tgccttcatg atccgtgtgc aaatcttgcg ctatcgtgac ttggaataca
    15181 acttggcgtc acgtactttg ggaacaccaa ccttgaagat tgttgccaaa aatatcatgc
    15241 ctcaattggt atctgttatt gtgacaacca tgactcaaat gcttccaagc tttatctcat
    15301 acgaagcctt cttgtctttc ttcggtcttg gattaccgat tacagtgcca agtttgggtc
    15361 gtttgatttc ggattattca caaaacgtaa caaccaatgc ttacttgttc tggattccat
    15421 tgacaaccct tgtcttggta tccttgtccc ttttcgtagt tggtcaaaac ttagcggatg
    15481 ctagtgatcc acgtacacat agataggagt agaaatgaca aaagaaaaaa atgtaatttt
    15541 gactgctcgc gatattgtcg tggaatttga cgttcgtgac aaagtattga cagccattcg
    15601 cggcgtttcc cttgaactag ttgaaggaga agtattagcc ttggtaggtg agtcaggatc
    15661 aggtaaatct gttttgacaa agaccttcac aggtatgctc gaagaaaatg gtcgtattgc
    15721 ccaaggtagt attgactacc gtggtcagga cttgacagct ttatcttctc acaaggagtg
    15781 ggaacaaatt cgtggtgcta agattgcgac tatcttccag gacccaatga ctagtttgga
    15841 ccccattaaa acaattggta gtcagattac agaagttatt gtaaaacacc aaggaaaaac
    15901 agctaaagaa gcgaaagaat tggccattga ctacatgaat aaggttggca ttccagacgc
    15961 agatagacgt tttaatgaat acccattcca atattctgga ggaatgcgtc aacgtatcgt
    16021 tattgcgatt gcccttgcct gccgacctga tgtcttgatc tgtgatgagc caacaactgc
    16081 cttggatgta actattcaag ctcagattat tgatttgcta aaatctttac aaaacgagta
    16141 tcatttcaca acaatcttta ttacccacga ccttggtgtg gtggcaagta ttgcggataa
    16201 ggtagcggtt atgtatgcag gagaaatcgt tgagtatgga acggttgagg aagtcttcta
    16261 tgaccctcgc catccatata catggagtct cttgtctagc ttgcctcagc ttgctgatga
    16321 taaaggggat ctttactcaa tcccaggaac acctccgtca ctttatactg acctgaaagg
    16381 ggatgctttt gccttgcgtt ctgactacgc aatgcagatt gacttcgaac aaaaagctcc
    16441 tcaattctca gtatcagaga cacattgggc taaaacttgg cttcttcatg aggatgctcc
    16501 aaaagtagaa aaaccagctg tgattgcaaa tctccatgat aagatccgtg aaaaaatggg
    16561 atttgcccat ctggctgact aggaggaagg aaatgtctga aaaattagta gaaatcaaag
    16621 atttagaaat ttccttcggt gaaggaagta agaagtttgt cgcggttaaa aatgctaact
    16681 tctttatcaa caagggagaa actttctcgc ttgtaggtga gtccggtagt gggaaaacaa
    16741 ctattggtcg tgctatcatc ggtctaaatg atacaagtaa tggagatatc atttttgatg
    16801 gtcaaaagat taatggtaag aaatcgcgtg aacaagctgc ggaattgatt cgtcgaatcc
    16861 agatgatttt ccaagaccct gccgcaagtt tgaatgaacg tgcgactgtt gattatatta
    16921 tttctgaagg tctttacaat caccgtttat ttaaggatga agaagaacgt aaagagaaag
    16981 ttcaaaatat tatccgtgaa gtaggtcttc ttgctgagca cttgactcgt taccctcatg
    17041 aattctcagg cggtcaacgt caacgtatcg gtattgcccg tgccttggtc atgcaaccag
    17101 actttgttat tgcagatgag ccaatttcag ccttggacgt ttctgtacgt gcccaagtct
    17161 tgaacttgct caaaaaattc caaaaagagc tcggcctgac ctatctcttc atcgcccatg
    17221 acttgtcggt tgttcgcttt atttcagatc gtatcgcagt tatttacaag ggtgttattg
    17281 tagaggttgc agaaacagaa gaattgttta acaatccaat tcacccatat actcaagcct
    17341 tgctttcagc ggtaccaatc ccagatccaa tcttggaacg taagaaggtc ttgaaggttt
    17401 acgacccaag tcaacacgac tatgagactg ataagccgtc tatggtagaa atccgtccag
    17461 gtcactatgt ttgggcgaac caaaccgaat tggcacgtta tcaaaaagga ctaaactagt
    17521 aatggtttta taatttccat gtcaattttt atggaaatta ggctctttgt caactgtagt
    17581 gggttgaagt cagctaagct cgagaaagga caaatttcgt cctttctttt ttgatgttca
    17641 aagcgataaa aatccgtttt ttgaagtttt caaagtttcg aaaaccaaaa gcattgcgct
    17701 tgataagttt gatgagatta ttggtcgctt ccagtttggc attagaatag tgtagttgaa
    17761 gggcgttgat aatcttttct ttatctttga ggaaggtttt aaagacagtc tgaaaaatag
    17821 gatgaacctg cttaagattg tcctcgataa gttcgaaaaa tttctctggt tccttattct
    17881 ggaagtgaaa aagcaagagc tgatagagct gatagtggtg tttcaagtct tccgaataac
    17941 tcaaaagctt gtttaaaatc tctttattgg ttaagtgcat acgaaaagta ggacgataaa
    18001 attgcttatc actcagttta cggctatcct gttgtatgag cttccagtag tgcttgatag
    18061 ccttgtgttc atgggatttt cgatgaaact gattcatgat ttggacacgc acacgactca
    18121 tagcacggct aagatgttgt acaatgtgaa agcgatcaag aacgatttta gcattcggga
    18181 gtgaaacagt ctaggagact gtttcagcct gagcctagaa atttgaaagc gaagctgttt
    18241 agccaagtca tagtaagggc taaacatatc catagtaatg attttgacgc gacatcggac
    18301 ggctctatca tatttaagaa agtgatctcg gatgacagct tgtgttctac cttcaagaac
    18361 agtgatgata tcgagctttt caaaatcttg cgcaataaag ctcatctcca tctcccgatt
    18421 gaaacagtca ctccccggac tgtttcaacg tcccaagaca taatcttagg cagatttcta
    18481 aaattacact caaagtggaa gtcattgagc tttcgaatga cagttgaagt tgagatggaa
    18541 agctgatggg caatatcagt catagaaatc ttttcaatta acttttgagc aatcttttgg
    18601 ttgatgatac gagggatttg gtgattcttc ttgacgatag aagtttcagc aaccataatt
    18661 ttagaacaat gatagcactt gaaacgacgc tttctaagga gaattctagt aggcatacca
    18721 gttgtttcaa gataaggaat tttagaaggt ttttgaaagt aatatttctt catttgactt
    18781 ccgcactcag gacaagatgg agcttcatag tccagtttgg cgatgatttc cttgtgtgta
    18841 tccttcttga tgatgtctaa aatctggata ttagggtctt taatgtctag taattttgtg
    18901 ataaaatgta attgttccat atgattcttt ctaatgagtt gttttgtcgc ttttcattat
    18961 aggtcatatg ggactttttt tctacacaaa ataggctcca taatatccat aggggggtta
    19021 cccactacaa atattataga gccgaaaaag gctgagatct ggtgtctcag tcttttattt
    19081 cttgcgtttt gcaaaatcta caaatctaaa tttttctaac ttatggcgac tttcggtaaa
    19141 ctgaaattgg cgtccgtctt ggagatagac ttttgattta atcgaaacga cataagggtc
    19201 tttgccaatg tccatgagaa tcttgtctcg gtcgcttgag tggtcaatgg tgatttcctt
    19261 ctgagcataa tcaataagga gtttgaggcc attttctata taagaataga tagactgctc
    19321 agcaatttgg cgagtgagat ttggaattag ttccatatcc agatagtctg tatccagaac
    19381 ggataccaga tcatccacca cacgctggcg gaccaccttc caaaccatcc gaaactctgg
    19441 gaaaccggtt atcagtgagg attttttatc aataataatc ttgtccagac tgaccacgtt
    19501 ggttttagag cgcagtccaa gttctttaac tagttcttgg tagctggtta ggttggatac
    19561 agggaaattg acggtttctt ctttgacgac ttgagaacct tgccctctta tctttttgat
    19621 caatccttcc tcttggagga gagacagggc ctttcggacg gtatcacgac tcacttgata
    19681 ttgctccata aggtcgtgct cgctaggaag gaaatctccg acagcgtaag tctcgttttg
    19741 aatggtttct tggatttgct taaataattg ttggtatttc ttcattttgc ctgcttaaat
    19801 aggtttttag tctagtttaa tgaacacctg tatctatttt accatacaag tgctagaaaa
    19861 tttacaaaaa aacacccttt ttataccaaa caagttgcag acaagtttgg tatcgtttac
    19921 aatatactta tcaaatcaaa cttgctttga caagtataag gagaatcaaa tgggaaaatt
    19981 tgaacaagaa gccaaagatc tgcttcaggc aattggaggc aaagaaaatg tgactgccgt
    20041 cacccactgt gcgacacgga tgcgctttgt tttaggagat gataagaagg ctaatgttaa
    20101 agctatcgag tcaattccag ctgttaaagg aacttttaca aatgcaggtc aatttcaggt
    20161 aatcattgga aatgacgtgc ccatctttta taatgatttt acagccgttt caggtattga
    20221 gggtgtttcc aaagaagcag ccaagtctgc agctaagagt aatcaaaacg tggtccaacg
    20281 tgttatgacc actctggcgg agatttttac tccgattatt ccagccttga tagtcggagg
    20341 attgatcctc ggtttccgta atgtcttgga aggtgtccat tggtcgatgt tggatggcaa
    20401 gaccatcaca gaatcctctc agttttgggc aggtgtcaat cacttcctct ggttgcctgg
    20461 tgaagctatc ttccagttct taccagtagg gattacttgg tctgtttctc gtaagatggg
    20521 aaccagccaa attttgggaa ttgttctcgg aatctgtttg gtatcgcctc agttgctcaa
    20581 tgcctatgcg gttgcttcaa cgccagcagc tgatatcgcg gcaaactggg tttggaattt
    20641 tggctatttt actgttaatc gtatcggtta ccaagcccaa gttatcccag ccttgcttgc
    20701 aggtttgagt ctgtcttatc ttgaaatctt ctggcgcaag catatcccag aagtcatttc
    20761 tatgattttt gtacctttct tgtcattgat tccagccttg attttggctc atactgtttt
    20821 gggaccaatc ggttggacaa ttggacaagg actttcatca gttgtcttgg caggtttaac
    20881 tggtccagtt aaatggctct tcggtgcaat ttttggtgcc ctctacgctc catttgtcat
    20941 cacaggtctg caccatatga ccaatgccat tgatacacaa ttgattgcgg atgctggtgg
    21001 cactgcccta tggccaatga ttgctctttc taatattgct caaggctcag ccgtgtttgt
    21061 ctattatttc atgcatcgcc atgatgagcg tgaggctcag gtttcacttc ctgcaaccat
    21121 ttcagcctat ctcggtgtta cagaaccagc tctttttggg gttaacgtaa aatatattta
    21181 tccatttgtt gctgggatga ctggttcagc ccttgcaggc atgttatccg ttacttttaa
    21241 tgtaactgcg gcttctattg gtatcggtgg tttgccaggt attctctcta ttcaacctca
    21301 atacatgctg ccatttgcag gaactatgct agttgcgatt gttgttccaa tgctcttgac
    21361 tttcttcttc cgcaaggctg gtctctttac aaaaacagag ggcgatacga acttgcaggc
    21421 agaattcgtt gctcaagaag aagcagaatt tgtgaaccat gaaccagtag aacttacttc
    21481 ggtagaaatt atcagcccac taactggcca agtgaaagaa ttgagtcaag cgacggatcc
    21541 tatttttgca tcaggtgtca tggggcaagg tctagtcatt gaaccaagcc aaggtgagtt
    21601 gacctctcca gttaatggga cagtgacggt tcttttccct accaagcatg ccatcggcat
    21661 tgtctctgac gagggagttg aattgctcat ccacatcggt atggatacag taggtcttga
    21721 tggcaaaggt tttgaaagtc ttgtagtcca aggagatcac gttacagttg gtcagcaact
    21781 gattcgtttt gatatggatg tcattaaggc tgcaggtctg gtgacagaaa ctcctgttat
    21841 catcaccaac caagatgctt atacagcgac tattcccgga acttatccga caacgatcca
    21901 agctggagca tctctcatgg tcgctacacg aatctaatac tcttcgaaaa tctcttcaaa
    21961 ccacgtcagc tctatctgca acctcaaaat agtgttttga gcaacctgtg gctagcttcc
    22021 tagtttgttc tttgattttc attgagtata attgaaatag cacaaatagg gacggaagac
    22081 tgcttcctcc cttttatcag aaaaggagaa acagatgaca cttgataaag gaaaagtagt
    22141 ctatcaaatc tatccaaaat cttacaaaga caccactgaa aacggtattg gggatttccg
    22201 tgggattatc gaaaaaattc cctatttagc caaactaggt gtggatatgg tctggctcaa
    22261 tccattctat ccaagccctc aacgggataa tggttacgat atttcagatt atatggcagt
    22321 ggatcctctt tttggtgata tggctgattt tgaggaaatg gtgtgtgtcg gtaaagagca
    22381 caagattgac tttatgctgg acatggtact taatcattgt tcgacagagc atgaatggtt
    22441 tcagaaagcc ctagctggtg ataagtatta tcaagacttt ttcttcatcc aagaccaacc
    22501 aacagattgg cagtctaagt ttggtggttc tgcatggacg cctttcgggg atactgggaa
    22561 atactatctt cacctatttg atgagaccca ggctgacctt aactggcgca attccaatgt
    22621 ccgtaaggag cttttcaagg ttgttaattt ctggcgcgac aagggtatca aaggtttccg
    22681 atttgatgtg atcaatttga tcggtaagga cgaggtttca gtggactgtc ctgaaaatga
    22741 agggaagcca gcttatacag acaaacccat cgttcataac tatttgcgta tgatgaacca
    22801 agccactttt ggatctgacg atagctttat gacagttggg gaaatgtctt ctaccaccat
    22861 ggaaaactgt gtcctctatt cgtcgcctga tcgtcaggaa ttatccatga cctttaattt
    22921 tcatcacctc aaggtggact ataaggatgg acaaaagtgg accttggctc cctttgattt
    22981 tgaagagttg aagagtcttt accatagttg gggtaaggaa atgagtgata aagacggttg
    23041 gagtgccctc ttttggaaca atcacgatca accacgtgcc ttgaaccgtt ttgtcgatat
    23101 tcaaaacttc cgcaaggaag gagccaccat gctagcggct agcattcacc tgtcacgtgg
    23161 gacaccttat atctatatgg gtgaagaaat cgggatgatt gacccagact atgattctat
    23221 ggctgattat gtggatgtcg aatcgcttaa tgcctatcag acgctcttag aagaaggaaa
    23281 gagtcagcaa gaagccttcc agattattca agctaagtcg cgtgataatt cacgcattcc
    23341 catgcagtgg gatgcttcgg aaaatgcagg attttcaaca ggcactccat ggttgaaagc
    23401 tggtaaatcc tataaataca tcaatgtaga aaatgaaatc cagggtccga ttttcacctt
    23461 ctatcaagac ttgattcgac tgcgtaagga aatgccaatc atttcagaag gaagttacaa
    23521 accagccttt gaagatagca aacaagtcta cgcttttgaa cgccagtttg aggatcaaaa
    23581 gttactagtg ctcaataact tttatgctaa agaagtggaa atcgacttgc cagcagtcta
    23641 ccaaaatgga cagattttga tatcaaacta tgaagatgca gaagtgtctg agaaaattct
    23701 actcaaaccc tatcaaacac tggctattta tgtaaattaa tactcttcga aaatctcttc
    23761 aaaccgtgtc agttttatct gcaacctcaa agcggtgctt tgagcaacct gtggctagct
    23821 tcctagtttg ctctttgatt ttcattgagt ataaacttag caaggagacc tctttttcag
    23881 aaaagcaggg ttctttttgc tgtctattcc atccctgaaa gtgtagaaca aactggtcag
    23941 ggtggctagt ttgtggtata atgaaaggga ttcaaaaaga aacaggagaa aaatgatgga
    24001 tttactttta gcaattgtat tgattgtgct agcttttcta ggaggagctc ttggaggaat
    24061 gtacttggtt cgtaagcaaa tcgaaaaaga atttgctgac aacccacgtt tgaatgctga
    24121 agcagttcgt actcttttga gtgcaaatgg tcaaaaacca agcgaagcta aggtacaaca
    24181 agtttaccac caaatcatcc gccaacaaaa ggcagccctt gctaacaata aaaagaaaaa
    24241 ataaataagg aaaagtctgg gatgaaagtt ccagacttct cactatgttg gttatggttt
    24301 agggatgaga ctttttcctt gcattctatt gatatttgat tatgattaag agagaggtag
    24361 ttgacattct atcaagctgt cggtcagttc gttcagtaca aggaatcata atgaacgatc
    24421 aatcagaaaa aagactagaa agaagactgt atggataatc gaccaattgg ttttttggat
    24481 tcgggtgtcg ggggcttgac cgttgtgcgc gagctcatgc gccagcttcc ccatgaagaa
    24541 atcgtctata ttggagattc ggcgcgggcg ccctatggcc cccgtcctgc tgagcaaatt
    24601 cgtgaatata cttggcagct ggtcaacttt ctcttgacca aggatgtcaa aatgattgtc
    24661 attgcttgta acactgcgac tgcggtcgtc tgggaagaaa tcaaggctca actagatatt
    24721 cctgtcttgg gtgtaatttt gccaggagct tcggcagcca tcaagtccag tcaaggtggg
    24781 aaaatcggag tgattggaac gcccatgacg gtacaatcag acatataccg tcagaaaatc
    24841 catgatctgg atcccgactt acaggtggag agcttggcct gtcccaagtt tgctcccttg
    24901 gttgagtcag gtgccctgtc aaccagtgtt accaagaagg tggtctatga aaccctgcgt
    24961 cccttggttg gaaaggtgga tagcctgatt ttgggctgta ctcattatcc actccttcgc
    25021 cctattatcc aaaatgtgat ggggccaaag gttcagctca tcgatagtgg ggcagagtgc
    25081 gtacgggata tctcagtctt actcaattat tttgaaatca atcgtggtcg cgatgctgga
    25141 ccactccatc accgttttta cacaacagcc agtagccaaa gttttgcaca aattggtgaa
    25201 gaatggctgg aaaaagagat tcatgtggag catgtagaat tatgacaaat aaaatttatg
    25261 aatataagga tgaccaggac tggtatgttg ggtcttatag tatttttggt ggcgttaaca
    25321 gtttgagcga ctatcagaca gattttcctc tgtttgaatt ctccaaaata tttggagatg
    25381 aagagtatgg tttcccgctt tcagttactg ttttacgcta tggttctacc taccgtttgt
    25441 tctcctttgt ggtagatatg cttaatcaag aaatgggacg aaacttggaa gttattcaac
    25501 gtcatggggc cctgctcttg gttgaaaatg ggcaactctt gtatgtagaa ttgcctaaag
    25561 aaggggtcaa tgttcatgat ttctttgaga caagcaaagt cagagaaacc ttgttgattg
    25621 cgactcgtaa cgaaggtaaa accaaggaat tccgagctat ctttgataag ttaggctacg
    25681 atgtggaaaa tcttaatgac taccctgacc tgcctgaagt agcagaaaca ggtatgacct
    25741 ttgaggaaaa tgcccgcctt aaggcagaaa ccatttctca attaacgggc aagatggttt
    25801 tggcagatga ttctggtctc aaagtcgatg tccttggtgg cttaccaggc gtctggtcag
    25861 ctcgtttcgc aggtgtggga gcaactgacc gtgaaaataa tgccaaactc ttgcacgaat
    25921 tggccatggt ctttgaactc aaggaccgct cggctcagtt ccacacaacc ctagtcgtag
    25981 ccagcccaaa taaggaaagt ttagttgttg aagcagactg gtcaggttat attaactttg
    26041 aacctaaggg tgaaaatggc tttggctatg atcccctctt ccttgtagga gagacaggtg
    26101 agtcatcagc tgaattaacc ctggaagaaa aaaatagtca atctcaccgt gccttagccg
    26161 ttaagaaact tttggaggta tttccatcat ggcaaagcaa accatcattg taatgagcga
    26221 ttcccatggc gatagcttga ttgtggaaga agtccgtgat cgctatgtgg gcaaagtcga
    26281 tgccgttttt cataacggcg attctgaact acgtccggat tctccacttt gggagggcat
    26341 ccgcgttgtt aaagggaaca tggacttcta cgccggctac ccagaacgtc tggtgactga
    26401 gcttggttcg accaagatta tccaaactca tggtcacttg tttgacatca atttcaactt
    26461 tcaaaagttg gactactggg ctcaggagga agaggccgct atctgcctct atggtcactt
    26521 gcatgtgcca agtgcttggt tggaaggcaa gatcctcttt ctaaatccag gctctatcag
    26581 tcaaccacga ggtaccatca gagaatgtct ctatgctcgt gtggagattg atgatagtta
    26641 cttcaaagtg gactttttga cacgagatca cgaggtgtat ccaggtttgt ccaaggagtt
    26701 tagccgatga ttgccaagga gtttgagact ttcttgttgg ggcaggagga aacttttttg
    26761 acccctgcta aaaatctagc tgtgttgatt gatactcaca atgcggatca tgcgaccctc
    26821 ttgctcagtc agatgaccta tacccgtgtt cccgttgtga cagatgaaaa acagtttgtt
    26881 gggacgattg gactcagaga tattatggct tatcagatgg agcatgactt gagccaagaa
    26941 atcatggcgg atacggatat cgttcatatg acaaaaacgg acgtagcggt tgtttcgcct
    27001 gatttcacca ttacggaggt cttgcacaag ctagtagatg agtccttctt accggttgtg
    27061 gatgcagagg gtattttcca agggattatt acgcgcaagt ccatcctcaa ggccgttaat
    27121 gccctcttgc atgactttag taaggaatat gagattcgat gccaatgaga gacaggattt
    27181 cagccttttt agaggaaaag cagggcttgt ctgtcaattc caagcagtcc tataagtatg
    27241 atttggagca atttttagac atggtaggtg agcggatttc tgagaccagt ctcaagattt
    27301 accaagccca gctagccaat ctaaaaatca gcgcccagaa gcgaaagatt tcggcctgta
    27361 accaatttct atactttctc tatcaaaaag gagaggtgga cagcttttac cgcttggaat
    27421 tagccaaaca agctgaaaag aagacggaaa agccagagat tctataccta gactcttttt
    27481 ggcaggaaag cgaccatcca gagggccgct tgctagcgct cttaatccta gaaatggggc
    27541 tcttgcccag tgagatttta gccatcaagg ttgcggacat caatctggat tttcaggtgt
    27601 tgcgaatcag caaggcttcc caacggagga ttgtcaccat tcccacggcc ttgctttcag
    27661 aattggaacc cttgatgggg cagacctatc tttttgaaag aggagggaaa ccctattctc
    27721 gtcagtgggc ctttcgtcag ttagaatctt ttgtcaagga gaaaggtttt ccatccttat
    27781 cagctcaagt cttacgtgaa cagtttattc taagacaaat agaaaacaag gtcgatttgt
    27841 acgaaattgc aaaaaaatta ggattaaaaa cagtcctgac cttagaaaaa tatagataat
    27901 ggatattaaa ttaaaagatt ttgaaggacc cctggactta ctcttgcatc tggtttctaa
    27961 gtaccagatg gatatctacg atgtgcccat tacggaagtc atcgaacagt atctagccta
    28021 tgtctcaacc ctgcaggcca tgcgtctgga agtgacgggt gagtacatgg tcatggctag
    28081 tcagctcatg ctgattaaga gtcgtaaact ccttccgaag gtagcagaag tgacagactt
    28141 gggggatgac ctggagcagg acctcctctc tcaaatcgaa gaatatcgca agttcaagct
    28201 cttgggtgag cacttggaag ccaagcacca agaacgggcc cagtattatt ccaaagcgcc
    28261 gacagagttg atttacgaag atgcggagct tgtgcatgac aagacgacca ttgacctctt
    28321 tttggctttt tcaaatatcc tagccaagaa aaaagaggag tttgcacaaa atcacacgac
    28381 tatcttgcgg gatgagtata agattgagga catgatgatt attgtgaaag aatccttgat
    28441 tggacgagat caattgcgct tgcaggattt gttcaaggaa gcccagaatg tccaagaggt
    28501 catcaccctc tttttggcaa ccctagagtt aatcaaaacc caggagctga tcctcgtgca
    28561 agaggagagt tttggagata tctatctcat ggaaaagaag gaagaaagtc aagtgcctca
    28621 aagctagact tgatagagag gaaagatgag tactttagca aaaatagaag cgctcttgtt
    28681 tgtagcgggt gaagatggga ttcgggtccg ccagttagct gaactcctct ctctgccacc
    28741 gacaggcatc cagcaaagtt taggaaaatt agcccagaag tatgaaaagg acccagattc
    28801 cagtttggct ttgattgaga caagtggtgc ttatagattg gtgaccaagc ctcaatttgc
    28861 agagattttg aaggaatact ctaaggcgcc tatcaaccag agcttgtctc gggctgccct
    28921 tgagaccttg tccattattg cctacaaaca gccgattacg cggatagaaa ttgatgccat
    28981 ccgtggggtt aactcgagtg gagccttggc aaagttgcag gcttttgacc tgataaagga
    29041 agacgggaaa aaggaagtat tggggcgccc caacctctat gtgactacgg attatttcct
    29101 agattacatg gggataaacc atttagaaga attaccagtg attgatgagc ttgagattca
    29161 agcccaagaa agccaattat ttggtgaaag gatagaagaa gatgagaatc aataagtata
    29221 ttgcccacgc aggtgtggcc agtaggagaa aagcagaaga gctgattaag caaggcttgg
    29281 tgacggttaa cggccaagtg gtgcgtgaac tagcaaccac tatcaagtca ggcgacaagg
    29341 tcgaagttga aggtcaacct atctacaacg aagaaaaggt ttactatctg cttaacaaac
    29401 cacgcggtgt gatttccagt gtgacagatg ataagggtcg caagacggtt gtcgacctct
    29461 tgcccaatgt caaagaacgt atttaccctg tgggtcgttt ggactgggat acatcaggtg
    29521 tcttgatttt gaccaatgat ggggacttta cagacgagat gattcaccct cgtaatgaga
    29581 ttgacaaggt ttatgtcgcg cgtgttaaag gtgtggccaa taaggacaat ctccgcccct
    29641 tgacccgtgg tcttgagatt gatggtaaga aaaccaagcc agctgtttat gaaattctca
    29701 aagtggaccc agtcaaaaat cgctctgtgg tgcagttgac catccatgaa gggcgtaacc
    29761 atcaggttaa aaagatgttt gaagctgttg gtctccaagt agataagttg tctcggactc
    29821 gtttcggaca cctagacttg acaggactcc gtccaggaga atcccgtcgt cttaataaaa
    29881 aagaaatcag ccaactacac accatggctg taactaagaa ataatgaaac gaattttaat
    29941 agcgcctgtg cgcttttacc aacgttttat ctcaccagtc tttccaccct cttgtcgctt
    30001 tgagctgact tgttccaact acatgattca ggctattgaa aaacatggtt ttaagggggt
    30061 attgatgggc ttggctcgga ttttacgttg tcatccctgg tcgaaaacag gtaaggaccc
    30121 cgttccagac cacttttccc ttaaacgaaa tcaagaaggg gaatgaggtg gggtaaatag
    30181 atttcaaaat gataaaaacg catcctatca ggtttgagtg aacttgatag gatgcgtttt
    30241 agaatgtcaa aattttatac tcttcgaaaa tcccttcaaa ccgcgtcagc tttcatctgc
    30301 aacctcaaaa cagtgttttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt
    30361 cattgagtat taaattgagt ttgaagtggc ttatttcaaa gctttttgta tgtcttcaat
    30421 catgagtttt gttgattcaa gtccgcctcc gcttagatac cagaggtctg gtgttagttg
    30481 gataatctta ccatttttag cagcaggtgt ttcagcgata agggcatttt ctaggacacc
    30541 gtcgttgcta gagttgtccc caccgatggc aagggtacgg ttgatgacaa agaggatgtc
    30601 agggttgatt tctttgacac tttcaaagct gacttcttgt ccgtggcgtg agtcttcaaa
    30661 tgttgtatca gttggtttga atttcaaggt ttggtacaag aaagagaaac gagatttggc
    30721 accaaaggct gccatttttc cttcattaag gaggatcgca agggcctttt tgtcagagct
    30781 ttcattttta gtagcgactt cttggatgct cttgtctagc ttggccaatt cttccttggc
    30841 tttctgtgta ccagtttcgc cgaaggcact tgctaaggat tcgatattag ccttggtaga
    30901 agtccagtag tcgtccttgc ttgcttggaa gagaacggtt ggggcgattt ctttgaattt
    30961 gtctacgaat ttttgtgtac gtggtgaagc gataatcaaa tcaggctcaa gggcggcgat
    31021 agcttctaaa tcaggttctt tcatagaacc aacatttttg acagttccca ctaggtcttt
    31081 tagataagtc ggaacagttt ttgtaggcat tccgacgata tttttttcaa atcctaaagc
    31141 gcgaatagta tccgcagcgc cgaggtcaaa ggtcacaatc ttttcaggaa ctttggaaag
    31201 tttgacctcg tccagtgaac ttttaatggt tacctctgtt ggagcagagc tactggtctc
    31261 tgtctgacta gtgcttgagt ttgtactaca tgcaccaagt aggagcaaga agctggccac
    31321 tagggcagtg aaataaagtt taagggatgt tttcataatt tctccttttt aaaatgtgat
    31381 aacgatttag ggagtctctt gatcttattg attaagagac tgaaggttct ctaacttgag
    31441 cttttatgtt actagctata gatacagatc tttttgtcat tgatatcagc tagcgtgatg
    31501 ggaatctcat aaagttggct gagcaggtca gcctgcatga tttgatcggt gcttcccttg
    31561 ctaaagacct gaccgtcctt gaaggcgaca atttcatctg catactgact ggccatgttg
    31621 atatcgtgga ggacgatgat aatggtcttg ccgagttcct ccaccagtcg tcgaagaatt
    31681 tgcatcatgc tgacgctttg cttgatatcg agattgttga gtggttcgtc cagcaagata
    31741 aagtccgtat cctgggccag taccatagcg ataaagacgc gctggagttg cccccctgac
    31801 aggctattga tgtagcggtc ttttaagttg gtcagttcca aatagttcag agtttctcgg
    31861 attttttccc agtcttctga tctaagtcga cctcggctgt agggaaaacg tccaaaactg
    31921 accagttctt caacagtcaa tttggcttgg taattgattt tctgttttag gatggttagt
    31981 tcttgggcca gttcttgcga attccagctc tcgatttcac gtcctttgat actgagaact
    32041 ccctgatctt tcttggttag tctgctcatg atggagagga gagtcgattt tccagcacca
    32101 tttggaccaa taaaggctgt cagtttttga ggactgactt caagcgaaat gccttgcaaa
    32161 atatcctgtt tttgaatgga tttgtcaatg ttttccagtt tcactgacga gccctcctat
    32221 atagtaagat aaagaataag aagccaccca cactctcaat gatcatactg atacgaattt
    32281 ccagtgcaaa gactcgttca atcaaggctt gccccaaggt taagctaata aatccaacca
    32341 gaatggccac tataaagagt aacttgtgct gatagtcttt gacaatcagg taggtgaggt
    32401 tggccagcat aaagccgaag aaggccatag gtcctaccaa ggcagtggcc gttgaggtca
    32461 aaagcacgat tccccagagg agctctttct gttctttttc aacatcgagt cccaatatct
    32521 gagccgtttc tctttgcagg tgcaagacat ctagaacgac tgcttttcga aagaaaaaga
    32581 ttgtcaaagc gaggatgatc agagaaccga tggctaggat ggaagtgtta agatgttgaa
    32641 aggaggcaaa aagactattt tgcagtttat cgtattcgtt tggatccatt aggacttgaa
    32701 ggaaggtgct gatatttcga aagagacttc tgagcgctag acagatcagc aggatgaaga
    32761 ccaggtcttg cttcatcagt gtcttcaagt aaccttgtaa ggcgagaaag aagagggact
    32821 ggacaagaag taagactagg aattctaaga taggggattt gccaagttga agaaacttgc
    32881 tttcaaaaac cagtagtagg gtttgtagta ggacgtagaa ggattcaatt cccaaaatac
    32941 taggcgtcag gaagcgattt tccgtcaagg tttgaaaact aatggtcgaa atcccagtcg
    33001 cgatggctac caagagataa acgatgatct tttgggaacg caacttccaa gcaaaggctg
    33061 acaagtgagt gatgggccaa aagtagagaa gacaagctcc gatggcaaga ataatgagaa
    33121 tccagaagag cttggtatgt ttgcttttag tctgcatctt ttcgtccccc tctccagaga
    33181 agtaggataa agacgagact accgatgatt cctagcaaga gactgacaga caactcatag
    33241 ggcctaatca gaactcggga taggatatcg caagccagaa ctagattggc accaaccagt
    33301 gcgaccatga gtttggtttg acttagatta tctccatagc acttgcgaac aagattggga
    33361 acgataactc cgagaaatgg taggccaccc acggtaatca tggtgacgct tgtcgttagc
    33421 gccaccagaa agagggccag tttttcaagt agggagtagg aaatccccaa actctcgctg
    33481 gtttctttcc ctagattcat gatggtgaag gtttgggata atttccaaac ggttatcagg
    33541 atgatgaggc ctaagaagag ccactcatac tgatgggtct gaatcatgga gaaggagccc
    33601 tgggtccagg cagtcatact ctgaaccaga ttgaaacgat aggcgataac ttctgtgact
    33661 gagccgataa tcccgctata gatgatccca atcagaggca acatccacct ttcctttaca
    33721 gtaaaaatgg tcataaaggc taggaagaag agggtgaata cgatggatga aacaaaagcg
    33781 aagagcatct tttgggtcag actagccgat ggaaagacaa aaaggctcag caccattccc
    33841 agtttggcgg cttcagtcgt tccaactgta ctcggtgcag caaactgatt ttgggtaata
    33901 gtctgcatga gaaggcctgc catactcata ctagaggcag tcaggagaat actgatagtt
    33961 cttgggagac gggactcttg aaagaggagc caggtctgct ggtcgaaatc aaatagcttt
    34021 ccccatgaaa aatcactggt cccaatgcta atagagagaa agactaggag tagaagtaag
    34081 ccaattaaat aatgagaaag tttcataccc cgtcctttca tgtagatttg gtatcgaaag
    34141 atatctgcgg atataaatgt aacattattt ttctaatctg tcaataaaat ttctgacaat
    34201 ttaataaata caacaaggag agagcaacaa gactttctcc tttgttatcc tattctaaaa
    34261 tgtttttacc ttaatctgat aaaataatat cttcgaggga gtagctagcc gtccaatcaa
    34321 gatattgttt agcttttgaa gcatctgcta ggacactggc tgggtcacta gcacgtcgag
    34381 caacaatctc gtgtgggatt ttttaattta gtaattcttc agcagtttta aagatttctt
    34441 tgatagtata gcctttttta gttcctaagt taaagatttg agaagaactg tcttcttgaa
    34501 ataggtagtt cattccttta acatgagcct atgcaaggtc caagacataa atgtaatctc
    34561 gaatacatga accgtcacgt gtatcgtagt catctccaaa tatttttaag ctatcatttt
    34621 gtcccaatgc ggtcttgttg atatttggaa tgatgtgagt tggatttttc acacgcagac
    34681 cgtttgaagc atccatttca gccccagcaa cattaaagta acggaaaata acatatttcc
    34741 agtcgtagcg attggccatc cagtaaatca ttcgttcgcc catcagtttt gtctctgtat
    34801 aagggttgac agggtcgatc agggtatctt cagtcgccgg cttgtcaata cagttatttc
    34861 catagagaga agcagtcgaa gagaacatga ttttttgagt gccaacttca gataagactt
    34921 tgagaacttg gtccctacca gcaacgttgg cagtgaagta tttacttgga ttttcaatac
    34981 tttcgctcac aacaatttca cctgcataat ggaggacagc atcaatctga ttttcttcta
    35041 agtaagcctt taaggcgcta gcatcataaa catccagttc tttaaagcta gcacgattat
    35101 ccacagtcgc tcgatttcct gtggagagat tatcgaggac atgcacctta taaccagcat
    35161 ttaaaagagc tttaacggta tgggagccaa tgtagctagt cccacctgta acaagaattg
    35221 ttttggtcat gattttttcc ttttctagtt ttgtactata gtaaattgaa ataagatatg
    35281 aacaactcta ttaggaaagg caaattaatt cctagaaatg ttttagcagc tacagcgtac
    35341 tattccaaac tcaaccaact atatatttaa agaaagaaga aaaggaagtc aactattttc
    35401 tgtaaatttc atgaaaaatc caaacaactt tgatggtgta ttgttttttt gtttggaaat
    35461 aaatattcga gttaattttg gaatgtttac tagattttgc actacatgca agagaatact
    35521 atccttttct aagatagagc aggactaaga tactaactta gaaatccacc ttcccactat
    35581 ccttctccta taaaaagtgg taaaatggat gaaagaaaga aggaactgaa atgacaacat
    35641 tattttcaaa aattaaagaa gtaacagaac ttgctgcagt ctcaggtcat gaagcgcctg
    35701 tccgtgctta tcttcgtgaa aagttgacac cgcatgtgga tgaagtggtg acagatggct
    35761 tgggtggtat ttttggtatc aaacattcag aagctgtgga tgcaccgcgc gtcttggtcg
    35821 cttctcatat ggacgaagtt ggttttatgg tcagcgaaat caagccagat ggtaccttcc
    35881 gtgtcgtaga aatcggtggc tggaacccca tggtggttag cagccaacgt ttcaaactct
    35941 tgactcgtga tggtcatgaa attcctgtga tttcaggttc tgttcctccg catttgactc
    36001 gtggaaaggg gggaccaacc atgccagcca ttgccgatat cgtttttgat ggtggttttg
    36061 cggacaaggc tgaggcagaa agttttggca tccgtcctgg tgataccatc gtaccagata
    36121 gttctgcaat tttgacagcc aatgaaaaaa atatcatctc aaaagcttgg gataaccgct
    36181 acggtgtcct catggtaagc gagctagctg aagctttatc aggtcaaaaa ctcggcaatg
    36241 aactctatct gggttctaac gtccaagaag aagttggtct gcgtggcgct catacctcta
    36301 caaccaagtt tgacccagaa gtcttcctcg cagttgattg ctcaccagca ggtgatgtct
    36361 acggtggtca aggcaagatt ggagatggaa ccttgattcg tttctatgat ccaggtcact
    36421 tgcttctccc agggatgaag gatttccttt tgacaacggc tgaagaagct ggtatcaagt
    36481 accaatacta ctgtggtaaa ggcggaacag atgcaggtgc agctcatctg aaaaatggtg
    36541 gtgtcccatc aacaactatc ggtgtctgcg ctcgttatat ccattctcac caaaccctct
    36601 atgcaatgga tgacttccta gaagcgcaag ctttcttaca agccttggtg aagaaattgg
    36661 atcgttcaac ggttgatttg attaaacatt attaaaccat aagggaggtg gtagggatgg
    36721 cagaaccaaa cctagaaagc cttataaaag atctttacaa tcatgctcga catgatttga
    36781 gtgaagattt agttgctgct ctcctagaga ctactaaaaa actgcctact acaaatgagc
    36841 aattgcaggc agttcgtctc tcaggcctgg tcaatcgtga attgctccta aatcccaaac
    36901 atccagcacc tgagttgctc aacttggctc gctttatcaa aagagaagaa gccaagtaca
    36961 gaggaactgc gacttctgca cttatgtatg aggaactttt taaaatgctt tgattccatt
    37021 gtggatcaaa gcatttttta taagacctat ctcgtgagcg ttcaaatagt agtaacaagg
    37081 aatcatgaga agtcagccga gaccatagta gtgaagaaac ttctgtaatg gaagtggagt
    37141 gaagtgagga atcgtcaaac ggtaggggat aggctgtttg aagggtgcta cgaaaaagat
    37201 agggtaaggt gaaattatag cggaatgaaa taagatatga acaaattgat tagggaaatc
    37261 aaatgaattt atagaaatct tttagcagtc atggtgtcct attccagttt cgaaatgcta
    37321 taaagccgaa caaattgatt gggaaattca aatcgctttc tatcaatgtt ttagaagata
    37381 cagtgcccta gtccaacttc aatatactat aaaagaacag atggaagcaa ttatgattta
    37441 cttctatctt taaaataaat gatctgatag gaaaaatgtg tcccctcata aaatatagga
    37501 tagtacggat ggaaggcttt tgtagactgg aggacgaagg agtttagaaa ctctcgttaa
    37561 aagttagttg agccggagta tggtggtgtg gataattatc aaaaattatt tctaaatcga
    37621 aatagttgac agttagaacg atgagtgtta caattgtttt attcatttcg atatcgaaat
    37681 aaattggagg tgttatgaaa gatggtcatt tgctagccca tcatattcgt ttgttgaatg
    37741 ggcggatttt tcaaaagtta ctgagtcaag atcctgaggc tctttatagg ggtgaacagg
    37801 gcaagatttt agcggtttta tggaatagtg aaactggctg cgcaactgcg acagatatcg
    37861 cgcttgcgac tgggcttgcg aataatacgc tgacgactat gataaaaaag ctagaggaac
    37921 aaaagcttgt aattgttagt ccgtgtggaa aagacaagcg taagaagtat ttagttttaa
    37981 cggagttagg caagtcccag aaagaagtgg ggcatcgtgt cagtcagaaa ttggatacta
    38041 tcttttacaa aggattttca gaggaagaaa ttcaccaatt tgaaggtttt caagaaagaa
    38101 ttttggcgaa tctgaaagag aagggaaatg aggtttagaa tatgtcacaa caagtgaaaa
    38161 atgctcacaa cctatacatc catgccattc aagacggacg agttgctgag gctcaagccc
    38221 agtctgtagg ggatacctat atccaacatt cgacaggtgt tcctgacggg aaagaaggat
    38281 ttgcagcctt ctttgcagat ttctttgagc gtcatccaga gcgtcagatt aagattgtcc
    38341 gcaccattga ggatggcaat ctggtctttg ttcatgttca tcaatatctg aatggtggag
    38401 aagctcaatg ggtgacgacg gatactttcc gtgcggatga gaatggtcgt attgttgagc
    38461 attgggatgt cattgactac tatcgaacac ctgaaaatga ccaactagat caaatttttg
    38521 gagattttga aatcaaggat ttggacaaga aagcagaaaa taaaaagctg gttcgccgtt
    38581 tcttgacaga aattttccaa aatggggagc tagagcagtg gagtgattat gtggcagacg
    38641 atttgattca gcataatcat gatattggac aaggaagtgc tgcttataaa aactatgtgg
    38701 ctgaatatag tgtcactttt gactttgttt tccaactctt aggacaagga aactatgtgg
    38761 ttagctatgg tcagactcag attgatggcg ttgcttatgc ccagtacgat atcttccgtt
    38821 tagagaacgg gaaaattgtg gagcattggg ataataagga agtcatgcct aaggtagaag
    38881 acttgaccaa tcgagggaag ttttaaattg aggacaaaga atgattgaat acaaaaatgt
    38941 agcactgcgc tacacagaaa aggatgtctt gagagatgtc aacttacaga ttgaggatgg
    39001 ggaatttatg gttttagtag ggccttctgg gtcaggtaag acgaccatgc tcaagatgat
    39061 taaccgtctt ttggaaccaa ctgatggaaa tatttatatg gatgggaagc gcatcaaaga
    39121 ctatgatgag cgtgaacttc gtctttctac tggttatgtt ttacaggcta ttgctctttt
    39181 tccaaatcta acagttgcgg aaaatattgc tctcattcct gaaatgaagg ggtggagcaa
    39241 ggaagaaatt acgaagaaaa cagaagagct tttggctaag gttggtttac cagtagccga
    39301 gtatgggcat cgcttaccta gtgaattatc tggtggagaa cagcaacggg tcggtattgt
    39361 ccgagctatg attggtcagc ccaagatttt cctcatggat gaaccctttt cggccttgga
    39421 tgctatttcg agaaaacagt tgcaggttct gacaaaagaa ttgcataaag agtttgggat
    39481 gacaacgatt tttgtaaccc atgatacgga tgaagccttg aagttggcgg accgtattgc
    39541 tgtcttgcag gatggagaaa ttcgccaggt agcgaatccc gagacaattt taaaagcgcc
    39601 tgcaacagac tttgtagcag acttgtttgg aggtagtgtt catgactaat ttaattgcaa
    39661 cttttcagga tcgttttagt gattggttga cagctctatc tcaacatttg cagttgtcac
    39721 ttttgacctt gttactagct attttgcttg cgattccctt ggctgttttt cttcgctatc
    39781 atgagaagct ggccgactgg gtcttgcaga ttgcaggtat tttccagacc atcccgtctc
    39841 tggccttgtt ggggctcttt atccctttga tgggaattgg gaccttgccg gctttgacag
    39901 ctctagtgat ttatgcgatt ttccctattt tgcaaaatac tatcactggg ctgaagggaa
    39961 ttgatccgaa cctgcaagag gctgggattg cctttgggat gaccagatgg gaacgtctca
    40021 agaaatttga aattccactc gccatgcctg ttatcatgtc tgggattcgg acggcagctg
    40081 ttttgattat cggtacggca accttggcgg ccttgattgg agcaggggga ctgggttcct
    40141 ttatcctgtt gggaattgac cgtaataatg ccagtttgat tttgattggg gcactttctt
    40201 ctgcagtgct tgctatcgcc tttaacttcc tactaaaagt aatggaaaaa gcaaaattac
    40261 ggacgatttt ctcaggtttt gccttggtgg ctttattact gggtctgtct tatagtccag
    40321 ctcttttggc tcaaaaagag aaggaaaact tgattattgc tgggaaaata ggcccagaac
    40381 cagaaatttt ggctaatatg tataagttgc tgattgaaga aaataccagc atgactgcga
    40441 ctgttaaacc gaattttggg acgacaagtt tcctttatga agctctgaaa aaaggtgata
    40501 ttgacattta tcctgaattt accggtacgg tgactgaaag tttgcttcaa ccatcaccca
    40561 aggtgagtca tgagccagag caggtttatc aagtggcgcg tgatggcatt gccaagcagg
    40621 atcatctagc ctatctcaaa cctatgtctt atcaaaatac ctatgctgta gctgttccga
    40681 aaaagattgc tcaagaatat ggcttgaaga ccatttcgga tttgaaaaaa gtggaagggc
    40741 agctgaaggc aggctttacg cttgagttta acgaccgtga agatggaaat aagggcttgc
    40801 aatcaatgta tggtctcaat ctcaatgtgg cgactatgca gccagctctt cgttatcagg
    40861 caattcagtc aggggatatt caaatcacgg atgcctattc gactgatgcg gaattggagc
    40921 gttatgattt acaggtcttg gaagatgaca agcaactctt cccaccttat caaggggctc
    40981 cactcatgaa agaagctctt ctcaagaaac acccagagtt ggaaagagtt cttaatacat
    41041 tggctggtaa gattacagaa agccagatga gccagctcaa ctaccaagtc ggtgttgaag
    41101 gcaagtcagc aaagcaagta gccaaggagt ttctccaaga acaaggtttg ttgaagaaat
    41161 gatgggacag agactttaaa catactgaac tcaacttcct taaacgacta gataaaagaa
    41221 tgctcagaca atttcgtctg ggcttttttg atgtgagaat gactgaatgt cacttaaaat
    41281 ggaaagaaag agaaaatttt catgattttc taaaatttta ctgtaaagac agttgactat
    41341 tcataaaata ggtgtataat attttgtgaa ctacttaaca aataagaggt ttcagctcat
    41401 gtcgactaag gttagaaatc ttgtgtatag gcagttcatt atctaataga gcgttgcgtc
    41461 cgaaagtcta tccagacacg gctctttaaa aacaaaagga gaaatgatgc atacttattt
    41521 gcaaaagaaa attgaaaata tcaaaacaac cctaggtgaa atgtcaggtg gttaccgtcg
    41581 tatggttgcg gctatggctg atttaggatt ttcagaaact atgaaggcta tctgggatga
    41641 cctctttgcc catcgtagtt ttgcccagtg gatttatttg ctggttttag gaagttttcc
    41701 tctctggctg gagttggttt acgaacatcg tattgttgac tggattggga tgatttgtag
    41761 cttgacaggg attatctgtg taatctttgt atcggaaggt cgagcaagta attatctttt
    41821 tggcttgatt aactctgtta tttaccttat tttggcccta cagaaaggct tttatggtga
    41881 ggtgctgacg acactttact tcacagtcat gcagccaatt ggacttctag tttggattta
    41941 tcaggcacag tttaagaagg aaaagcagga gtttgtcgcg cgtaaactgg acggcaaggg
    42001 ctggacaaag tatctttcca ttagtgtgct ttggtggttg gcctttggct tcatttatca
    42061 gtctattggt gccaatcgtc cctatcgtga ttcaatcaca gatgcaacca atggggtagg
    42121 gcaaatcctc atgacagctg tttaccgtga acagtggata ttctgggcgg ctaccaatgt
    42181 tttttcaatc tatctctggt ggggagaaag cctgcaaatt caagggaaat atctaattta
    42241 tcttattaac agtctagttg gttggtatca atggagcaag gcagctaagc agaatactga
    42301 tttacttaac taggaaaaga tgtttgaaag tgctgttttg agatttcgat taaaacagat
    42361 atagttgata atcaaggatt tatagtatga aaaagaggat cggcgggtcc tcttttgttg
    42421 ttgaaaagat aaaaaactca gtaacctaga aataagacaa ctgaagcttt actctatatt
    42481 caatttttag gaatgagaag gtctagataa aattggacaa cttcctggtc tgtgaaatct
    42541 tgaccttttt tgagccacca ggtcaatgtc tcgataaagt tggacatgac caagtgttgg
    42601 aggtaagaag taggcagatt agggtgggct tcttttaaat tatcagctag cacggaatag
    42661 acgtggtgct caagctctct ctggagttga cggaggaagt agtcattttt ggaaaatagc
    42721 agactggtga tatggtcttg gtttttatga aaatgcagaa agaggtgggc gaggtagtcc
    42781 tcggttgaaa tggcttgctc tctttcaaaa agatgatgga agaggtagcg gcagagctgg
    42841 tccagaagaa gctccttact ctcatagtga cagtaaaagg tggatcgtcc cacatctgcg
    42901 agatcaatga tatcctgaac agtagtggcc tcgtagccct tagcattcaa aagttgtata
    42961 aaagcttgat agatggcttt tttggttttg ctgatacggc ggtcaatgtt agtcatatgg
    43021 acacttaagg caaattgttc agaactgaat aaagctgacg ttttgcttct atcctttctt
    43081 tgagttttag tggataatga taatgaacaa ggtgttcata aatctattat aacaaaggaa
    43141 tgagaaatat gaaggcaaaa tatgctgttt gggtggcttt tttcttaaat ttgacttatg
    43201 ccattgttga gtttattgca ggtggaatat ttggttctag cgctgttctt gctgactctg
    43261 tgcatgactt ggtagatgcg attgcaattg gaatatcagc ttttttagaa acaatctcca
    43321 atcgtgaaga agacaatcag tacaccttgg gctataagcg gtttagcctg ctaggagcct
    43381 tggtaacagc tgtgattctc gtaacgggct ctgttctagt cattttggaa aatgtcacga
    43441 agattttgca tccgcaacca gtcaatgatg aggggattct ctggttagga attattgcga
    43501 ttactatcaa tctgttagcg agtctggtgg ttggtaaggg aaagacaaag aatgagtcta
    43561 ttctgagtct gcattttctg gaagatacgc tagggtgggt agctgttatc ctgatggcga
    43621 ttgttcttcg atttacggac tggtatatcc tagatcctct tttgtccctt gtcatttctt
    43681 tctttattct ttcaaaagcc cttccacgtt tttggtctac actcaagatt ttcttggatg
    43741 ctgtgccaga aggtcttgat atcaagcaag taaagagtgg cctggagcga ttggacaatg
    43801 tggtcagcct taatcagctt aatctctgga ctatggatgc tttggaaaaa aatgccattg
    43861 tccatgtttg tctaaaagaa atggaacata tggaaacttg taaagagtct attcgaattt
    43921 tcctaaaaga ttgtggtttt caaaatatta ccattgaaat tgatgctgac ctagaaactc
    43981 atcaaaccca taagcgaaag gtgtgtgact tggaacggag ttatgagcat caacattaga
    44041 aaaaagtgaa aaatacttgg gtactatctt atttggaata gagtaatttc tttattattt
    44101 aaatatttca aaaattggta agagaagagc attgtataaa ctccagatat atgattgtta
    44161 atgataaaaa tttttcgatt agatacaaaa tgcttgactt ggagtcaact caaagttata
    44221 taataagata agtgagttag aatagcgtga actcagtgaa tgaaatgaga ggaggttagc
    44281 atgtgaatat taaatctgcc agtgatttgt tgggaatttc agcggatacg attcggtatt
    44341 atgaacgggt tggtcttgtg ccaccgatta ctcgtactgc tactgggatt cgtgattttc
    44401 aagatcagga tatcgaagcg ctggaattta ttaagtgttt tcgttcggcg ggtgtctctg
    44461 tagatagttt agttgactat atgtcgctct accaaaaggg agatgaaacg agagaggaga
    44521 ggcttggtat tttagaagag gaaaagcaaa aattagagga gcgcttgtct cagctacaga
    44581 cagctttaaa tcgtttaaat ctcaaaatta aactttataa ggaaggaaaa ttttaaatga
    44641 aatcagcagt atatacaaag gcaggtcagg ttggacttgc tagcattgaa cgtccgcaaa
    44701 taatagaagc ggatgatgtg attattcgtg tggttcgtgc gtgcgtttgt ggttcagatt
    44761 tatggaggta ccgtaatcca gaaacgaaag ctggacacaa aaatagtgga cacgaagcga
    44821 ttgggattgt tgaagaagct ggggaagccg ttacgacggt gaaaccaggt gattttgtga
    44881 ttgtcccttt tacacatgga tgtggtgagt gtgatgcctg tcttgctgga tttgacggtt
    44941 cttgcgacaa tcatattggc aataatttgg ggggtgattt tcaggcagaa tatattcgct
    45001 tccactatgc aaactgggcg ctggttaaaa tccctggtca accttctgac tatacagaag
    45061 ggatgctcca gtcccttttg actcttgcag atgtcatgcc gacaggctat catgcggcgc
    45121 gtgttgcaaa tgttcaaaaa ggggacaagg ttgttgttat cggtgatggg gctgttggtc
    45181 aatgtgctgt catcgcggct aagatgcgtg gagcatcaca aattatcctt atgagccgtc
    45241 atgaagaccg tcaaaagatg gctatggagt caggtgcgac agctgttgtt gcagaacgtg
    45301 gtcaagaagg aattaccaag gtgcgtgaaa tcctcggtgg aggagcagac gcagcacttg
    45361 aatgtgttgg tacggaggct gctatagaac aggcgctagg tgttcttcat aatggagggc
    45421 gtatgggctt tgtaggagtc ccacactata ataatcgtgc tcttggttcg acatttatgc
    45481 aaaatatctc tgtagcaggt ggggcagctt ctgctacaac atacgataag caatttttac
    45541 taaaagccgt ccttgatggt gatatcaatc caggtcgcgt ctttacttca agttataaac
    45601 tggaagatat cgaccaggcc tataaagata tggatgaacg taagaccatt aagtctatga
    45661 ttgtaatcga ataaaaaacg aataggagtt ttagaactct attcgttttt tatgttatcc
    45721 tattcttgat ttagggtact ttctcttaat gtcagtctgg ttcccagcat ggtcaggcta
    45781 gggattttcc gaccgtggag gacttccttg ttaagaatat ccatacctgc tcgccccatt
    45841 tcttcagtat agactgtgat gctggagagg ggaggataaa cctgcttggt cagactggtg
    45901 tcgttgaatg aaatgaggct gacgcgatct ggcaggctga ttccagcttc ttggagggca
    45961 cggagggcac cgatagctaa actatcgctg gctgcgaaaa atgctggcgg aagttggtct
    46021 cccaagctct gaatggcctc cttcattaag tcatagccag actgggcagt aaatcttcct
    46081 tgaaagacca gttcatcatg atagattccc ctcgcttgac tgtagttttt gaagttttct
    46141 agacgcttgt cctgaatgat ttcttcttgg tctgttgttt cctcaagccc tgttagaatc
    46201 ccgatgcggt ccatcccttg actgaggaaa taatcgacaa cctgtttcat agcagtgtaa
    46261 aaatccgtga taatacaggt atgtcccagg gaaagtgtat cgctgtctag aaatacaaga
    46321 ggcttttggt attcttcaaa ggcagaaatc tgagctcggc taaattttcc gatgcagaga
    46381 atcccaatca cttcctcgct taaggtaaaa ggatggtcat taaaatagcg caagatatcg
    46441 tagtccaact cttgggctct tttttctatt cctaggcgaa tctggtagta gtagaggtcg
    46501 tctagctccc cttgttcgct gacccattgg ataatggcaa tcttttgctt gggcttgtgg
    46561 gactcgcctg tcttgaggtg tttggtgtag cctaactctt cagcaacggt taaaatacgg
    46621 tgtctggttt cttctgtaac agataggctc tggtcgcggt tgaggacacg ggatacggtc
    46681 gcgattgaga cagaggctag ctgtgcaatg tcttttaagg tagccataaa tcctccttga
    46741 ttaggttagt atatcatatt tttcttcttt ttactgatat tttagtaaaa ttttagtaaa
    46801 aaggattgac cttgggaaat ttcttggata caatagaaag aaaacgatta cacgttaaga
    46861 tggcttaacg gacagtcaaa ggagaattca tatggcacaa catcttacta ctgaagtcct
    46921 tcgcaaagac tttcttgctg tttttggtca agaagcagac caaaccttct tttcaccagg
    46981 ccgtattaat ttgattggtg aacacacaga ctacaacggt gggcacgttt ttcctgctgc
    47041 tatttccttg ggaacttacg gtgcagctcg taagcgtgac gaccaagtct tgcgtttcta
    47101 ctcagctaac tttgaggaca agggcattat cgaagtgcct ctcgctgacc tcaagtttga
    47161 aaaagagcac aactggacca attatccaaa aggtgtcctt catttcttgc aagaagctgg
    47221 gcacgtgatt gacaaaggtt ttgattttta tgtttatggg aatatcccaa atggtgctgg
    47281 cttgtcttct tcagcatcct tggagctctt gacaggagtc gtggcagagc atctctttga
    47341 tttaaaatta gagcgtctcg atttggttaa aatcggaaaa caaacagaaa acaactttat
    47401 cggagtcaac tctggtatca tggaccagtt tgctattggt atgggggccg atcaacgtgc
    47461 tatttacctt gataccaaca ccttagagta tgatttggtg ccacttgatt tgaaggacaa
    47521 tgtcgttgtt atcatgaaca ccaacaaacg ccgtgaattg gcggactcta aatacaatga
    47581 acgtcgtgct gagtgtgaaa aagcagtgga agaattgcaa gttgccttgg atattcagac
    47641 cctgggtgaa ttggacgagt gggccgttga ccaatatagc tatttgatta aagatgaaaa
    47701 tcgtttgaaa cgtgctcgcc atgctgtgct tgaaaaccaa cgtaccctta aagctcaagc
    47761 agcccttcaa gcaggtgatt tggaaacatt tggtcgtttg atgaatgcgt cacacgtttc
    47821 tctggagcat gattatgaag taactggttt ggaattggat actcttgttc acacagcttg
    47881 ggcacaagaa ggagttctcg gtgctcgtat gacaggggct ggttttggtg gctgtgccat
    47941 tgccttggtt caaaaagata ctgttgaggc ctttaaggaa gctgtaggca aacactacga
    48001 ggaagtagtt ggatacgctc caagcttcta tatcgctgaa gttgcaggtg gcactcgcgt
    48061 ccttgactag tcaaaaggag gctctatagt gatcttagta gataaatttg taacacatgt
    48121 catttctgaa agttcatttg aggaaatgga tcgaatctac ctgaccaatc gtgttttggc
    48181 acgagtggga gaaggtgttt tggaagttga gaccaatctg gataaattga ttgacctcaa
    48241 ggaccagcta gttgaggaag ccgttcgatt agagacgatt gaggatagtc agactgcgcg
    48301 tgaaatcctt ggtactgaat tgatggactt ggtgactcct tgtccgagtc aggtcaatcg
    48361 tgacttctgg gaagcctatg cctactctcc tgagcaagcg atagaggatt tttatcaact
    48421 cagtcagaaa aatgactaca tcaaactcaa ggccattgct aaaaatatcg cttatcgtgt
    48481 tccatctgat tatggagaac ttgaaattac catcaatctc tctaagcctg aaaaggatcc
    48541 gaaagagatt gcggcagcca agttggtgca agctagtaat tatcctcagt gtcaactttg
    48601 tttagagaat gagggttacc atggtcgggt caaccaccca gctcgcacca accaccggat
    48661 tatccgtttt gaaatggttg gtcaggaatg gggtttccag tattcgccct atgcttactt
    48721 taatgagcat tgtatctttt tagatggcca gcatcgtccc atggccatta gtcgtcagag
    48781 ttttgaacgt ctgttggcta tcgtagagca gtttccagga tattttgctg gatctaatgc
    48841 cgacctgccg attgtggggg gctctattct aactcatgat cattatcagg gaggccgtca
    48901 cgtatttcct atggaattgg ctcccttgca aaagaccttc cgatttgctg gttttgagca
    48961 ggtcaaggct ggaattatca agtggccaat gtctgtccta cgcttgactt cggattccaa
    49021 agaggatttg attaacttag ctgataagat tttccaggaa tggcgtcagt attcagattc
    49081 tagtgtgcag attttagcag agacagacgg gacaccgcat cacaccatca caccaatagc
    49141 gcgtaagcgt gatggacagt ttgagttgga cttggtcttg cgagacaatc agacttcagc
    49201 agagcatcct gatggcatct atcatcccca caaggatgtc caacatatca agaaggaaaa
    49261 tatcggcttg attgaggtca tgggcttggc aatcttgcca ccacgtctga aagaagaagt
    49321 ggagcaagtc gctagctatc ttgtaggaga agctgttaca gttgccgatt atcatcagga
    49381 gtgggcagac caactcaaat cccaacatcc agacctaacg gataaagaaa aagcccttgc
    49441 aatcgtcaag gactctgtgg gggctatctt tgtgcgtgta cttgaggatg caggagtcta
    49501 caagcagaca gagcagggac aggcggcctt tatgcgcttt gtggaacagg tcggaatttc
    49561 actagactag gagctttctc cttgcacagt cctataaaaa gtagtatcat agtgtcgttt
    49621 gaaatatcag gaggaaacga tgaaagactt tcattttgac gctatatctg cctttgaaaa
    49681 ttacgaaatt gaaaaaatga gagatggtca cgttgtggtg acgaccaaag tagtgaactc
    49741 gtcgctcaac tactatggca atgcccatgg tggctatcta ttcacgctat gtgaccaaat
    49801 cagtggtttg gtggttatct cgctgggact tgatggggtg acactccaat cctctatcaa
    49861 ctaccttaag gcaggaaaac tcgacgatgt attgaccatt aaaggagaat gtgtccatca
    49921 aggtcgtaca acctgtgtaa tggatgtgga tatcaccaat caagaaggca gaaatgtctg
    49981 caaagcaacc tttaccatgt ttgtcacagg ccggcggtca gaagacagac aggtaaggat
    50041 ataaagagta atttaataga gtgaggtgaa ttttggaatt tataagattt gccttactca
    50101 ttttttgata ttgatatgat ttaattctaa aatagaaaat ttagtaatgt ggtagaaaat
    50161 acaagagttg tgttttaatt tctatggtat aattaaaagc atgaagataa aagaaataaa
    50221 gaaagttact ttacaaccgt tcacgaaatg gacaggtggt aaaagacaat tattgcctgt
    50281 tattagagaa ttaataccta aaacctataa caggtatttc gaaccttttg ttggaggtgg
    50341 agctttattt tttgatttgg ctcctaaaga tgcagttatt aatgatttta acgctgaact
    50401 aataaattgc tatcaacaaa ttaaggacaa tcctcaagaa ttgattgaaa ttttgaaagt
    50461 tcatcaggaa tataattcaa aagaatatta tttagattta cgttctgcag atcgtgatga
    50521 aagaatagat atgatgtccg aagtacaaag agctgcacgt attctatata tgttgagagt
    50581 gaactttaat ggtctatatc gtgtgaattc taagaatcaa tttaatgttc catatggacg
    50641 ttataagaat cctaaaattg ttgatgagga attgatatct gctatttcag tttatataaa
    50701 taacaatcaa ctagaaatta aagtgggaga ttttgaaaag gcaattgtag atgttcgaac
    50761 aggagatttt gtgtattttg accctccata tattccattg tctgagacga gtgcatttac
    50821 gtcttatact catgagggat tctcttttgc agatcaagta agattaagag atgcctttaa
    50881 gagattgagt gatacaggag cttatgttat gttatcaaat tcttctagtg ctttagtaga
    50941 ggagttgtat aaggatttta atatacatta tgttgaagct acccgaacta atggagcaaa
    51001 atcttcaagt cgaggaaaaa tttctgaaat tatagtcaca aattatgaaa aataacgaat
    51061 ataagtatgg aggtgttctt atgacaaaac catactacaa taaaaataag atgattcttg
    51121 ttcattcaga tacgttcaag ttcttatcaa aaatgaaacc agaaagtatg gatatgattt
    51181 ttgctgatcc accttatttt ttaagtaatg gtggaatatc taattctggg ggacaagtag
    51241 tttctgttga taaaggagat tgggataaaa tttcttcatt cgaagaaaaa catgagttta
    51301 atcgtaaatg gattcgccta gcaaaagaag ttctgaagcc taatgggacg gtatggattt
    51361 caggtagttt gcacaacata tactcagttg gaatggcatt agaacaagaa ggttttaaaa
    51421 ttctgaataa tattacttgg cagaaaacaa accctgcccc caatttatct tgtcgttatt
    51481 ttacccattc tactgaaacc attttatggg ccagaaaaaa tgataaaaaa gctcgtcatt
    51541 actacaatta tgatttaatg aaagaattga atgatggaaa acaaatgaaa gatgtctgga
    51601 ccggttcttt aacaaagaaa gttgaaaaat gggctgggaa acatccaact caaaaaccag
    51661 agtatttgtt agaacgtatt attttagcct ctactaaaga gggtgactat attctagacc
    51721 catttgttgg tagtggcact acgggtgttg ttgcgaagcg gttaggtaga agatttatag
    51781 gtatcgatgc tgaaaaagaa tatttaaaaa ttgcaaggaa gaggttggag gcagaaaatg
    51841 aaacaaacta gaaattttga tgagtggttg tcaacgatga ccgacacagt agctgactgg
    51901 acttattata cagattttcc taaggtttat aaaaatgtat ctagtataaa agttgctcta
    51961 aatattatga atagtcttat tggtagtaaa aatatacaag aggatttttt agacttatat
    52021 caaaattatc cagaaatttt gaaagttgtg cctctactta ttgctaaacg tttgagagat
    52081 acgattattg ttaaggatcc gataaaagat ttctattttg attttagtaa acgaaactat
    52141 agtattgaag aatatactat gtttttggaa aaatcaggta tatttgattt attgcaaaat
    52201 catttagtat caaatttagt tgactacgtt acaggtgttg aggttggtat ggatactaat
    52261 gggcgcaaaa atcggactgg agatgcgatg gaaaatattg ttcaaagcta tcttgaagct
    52321 gaagggtata ttttaggaga gaatttattt aaagagattg aacaaaatga aatagaggaa
    52381 attttttctg tcgatttatc tgctattacg aatgatggga atactgtgaa acgttttgat
    52441 tttgtcataa aaaatgaaca agtgctttat ctgattgagg ttaattttta ttcaggaagt
    52501 ggttcaaaat taaatgagac ggctagatct tacaaaatga ttgctgaaga aactaaagct
    52561 attcctaatg ttgagtttat gtggattact gatggacaag gttggtataa ggctaagaat
    52621 aatttacgag aaacatttga tattttacca ttcttatata atattaacga tttggaacat
    52681 aatattttaa agaatttgaa ataggtccaa ttcaattaga tgggaattgg gattgattgt
    52741 atttataatc aatttgtgat aaacaaaaaa gaggctcgca cctctttttc ttatttcttt
    52801 ttatgattta atacggcatt gaggacaata gcgagtaggc tggatacgac gattccgttt
    52861 gagaagaaca tttggaaggc tgtcggcatg ctgacaaaga gattactgtt gttgagaccg
    52921 acacctgcag cgattgaaac agctgcgata aggaagttgt gttcattgtt agcaaagtca
    52981 actcgggcga ggatttgcat cccttgaata gatacaaaac caaacatcac cagcatggca
    53041 ccgccgagga cggagcttgg aatgatttgg gcaagggcac caaacttagg aagcagtcca
    53101 aggagaacca ggaaaccagc tgcgtagtag attggcaggc gttttttgat gcctgacaat
    53161 ttaaccaaac caacgttttg tgaaaatccg gtgtaaggga aggtgttaaa gattcctccg
    53221 agaagtaccg ccaaaccttc tgcgcggtaa ccgttgcgaa ggcgcgtgct gtcgattgga
    53281 tcttttgtga tatcagacaa ggctagataa acaccagttg actcaaccat agacaccgtt
    53341 gcgatgatac acatcatggc aatagatgag atttcaaagg ttggcatccc aaagtagagt
    53401 ggagttggga catggacaag tggagctacc gcaacaggag agaagtccac caagcccata
    53461 gtagcagcaa tggcagttcc aacaaccaga ccaatcaaaa tagagataga cttgataaat
    53521 cctttggtaa agatgttgat caagaggata atcagaacag taatagctgc aagcaagaga
    53581 ctttgaccag ttggctctgg aacgttattt cccatatttc caatagcgac agggatcaag
    53641 gttaaaccaa tcgtggtaat aacagatcct gttacgatag atgggaagag attggctact
    53701 tttgagaaga tgcctgaaac aagaaccacg taaatcccag atgcgataag ggcaccaaac
    53761 atagcgccac taccatggct ttgcccaatc ataatcaagg gagcgaccga ctggaatgca
    53821 actccaagaa cgactgggag tccaatccca aagtatttgt tgagttggag ttggaggaag
    53881 gttgccaccc cacacatgaa gatatctgta gaaatcaggt aggtcaactg ctcagctgaa
    53941 tagccaaggg ctgtcgcaat catgatggga accaggatag atcctgagta catggctagt
    54001 aagtgctgca agccaagaac ggctgcttgc gagtgttttt cttgagtttg cattagagat
    54061 ctgcctcctt aaatacgacc tgaccatttt caaaacgatc caaacgagca agtgatagga
    54121 cagggtagcc tgctttttca agcaaatcac ggccatcttg gaaggatttc tcaatcacga
    54181 taccgatagc ttggactgtg gcaccggcct gttcgatgat ttgaatcaag cctttagcag
    54241 cttggccatt agcaaggaaa tcgtcgataa tcaaaacctt gtcctctggt gagaggaatt
    54301 ttccagcgat agaaacggtg ctggtcacct gtttggtaaa ggagtagact tgagcagtta
    54361 agatgccttc gttcatggtg atgttcttag cttttttggc gaaaatcatg ggaacgttta
    54421 aggcttcagc tgtaaaaacg gctggggcaa tacccgatgc ttcaatggtt acgaccttgg
    54481 taatgccagt agcagcaaat ttttccgcaa aaaccttacc aatctctcgc atcaagctaa
    54541 agtcaacttg gtgggttaaa aaggaatcta ccttgaggat gttatcaccc aagatatgcc
    54601 catccttgag gatgcgttct tctaataatt tcataagacc tcctaaagtc taaaagttaa
    54661 tttacttgtt gtttaaatgt ttctatagtg atcccttttg ctaatactat atatttgata
    54721 aaactattac gagcgaagcg agtcttatca aatatttccc gttgtagtgg tatcatagac
    54781 aataatcttg ttattgtcta tgacgggatt tttgagagta aaatagttcg gggaactatt
    54841 ttagcctaag cctagaaatg aaagagctag gggctcaaaa attagggatg aaattccctg
    54901 gattcctgaa attattcaca ggataatttc acctcccgtc cgcactaatt aagggaaata
    54961 ttaaaaatat tcaaaaaaga cctacttaat ctctaagtaa gtcccccaaa tagacatggc
    55021 aaaaacggcc atatctcact gctgacttac ttattgttag gtgttccggc accttgtaga
    55081 aacgtcgtgc caattcacga cataaacaag taaaacgata ttcaatttta aataggcttg
    55141 agccaatgtt tttattttac actaaataac tttagaaatc aactattttg ttagtgtttt
    55201 ggtttaaaaa acgaacaaac agaagagagg ggtgaacaaa aactccattg taagctaaca
    55261 tttatactaa atgaaaatca aagagcaaac taggaagcta tccacaacct caaaacattg
    55321 ttttgaggtt gtggatagaa ttgacagagt cagtatcata tacctacggt aaggcgacgt
    55381 tgacgtggct tgaagagatt ttcgaagagt attagaagat ttttccatca taaaaggcat
    55441 actatcaagt ttttagacac ctgacaatat gcctttttct aactttaaag acttttccca
    55501 atttttatta ttctactcgc taaatcttaa aaaatagcta tctggatcca aaactgcaaa
    55561 ttcatgagga tagatatagt gatcactgac acgaaacttt cttttggtca agggacgata
    55621 aataggatag tttgccttca tcactctttg atagagtttt gaaacatcct ttatgccaaa
    55681 ggagagattg actccacgac caaatagata ggtcagttca gctagttgat cctttgttcc
    55741 ctcctctaac attagttgac actcttcaag agaaagagaa agttttcttc tggacgttgg
    55801 tattcaatcc taaaacccag taaatcacag tagaaggacc gggactgttc gatattcgat
    55861 acaagcaact cgggaatgac cgcattgtag tccatataga aaatccttac aagtcaattt
    55921 ccaagacaat cggtgtatgg tcttggcgag cacctgagtc aatcatatca gatttagtga
    55981 ccttgtcagc gatacggtta cttgtgagcc agtagtcgat tctccagcct gtattgttga
    56041 ttttagaagt tttgctgcgt tgtgcccacc aagtgtagcg ttcaggaaca tcgccatgaa
    56101 catggcggaa ggtatcagta aatccagttg ccaataggtt ggtaaatcca gcacgttcct
    56161 cgtcagtaaa tccaggtgaa cggcggttgc tagcaggatt tgcaaggtcg atttcattgt
    56221 gggctacgtt gtagtcaccg gtcgcaagga ctggtttttc tttgtctagt tcagccaaat
    56281 actcagcata tttaacatcc cagacttggc gttcttccaa gcgtttaaga ccatcgccag
    56341 catttggtgt gtaaacttgg gtcacgaaaa atgcatcaaa ttctagagtg atgatgcggc
    56401 cttccaagtc catggtagaa ggggcaccga tttctgggaa agtgacagtg ggtgtaagtt
    56461 ctttcttata aaggaacatg gttccagcat agcctttacg tgcaggctct tgggaagagc
    56521 gccacgtgtt ttcgtagcct gggaagagtt cttctaaaat ttccacgtgt ttctttgtag
    56581 gtcctttggc agaaagcttg gtttcttgga tagcaatgat atcagcattt tcagcgacca
    56641 aggtttgtag gacttcttgg gacaatttgg cacgagctga gtcactagtt agggcagcgt
    56701 ttagggaatc aatattccat gagataagtt tcataaagtt accttttcat tcagattata
    56761 gattttatta taccaaaaaa agatctattt ccccaacgta tggtttgaaa aattactctc
    56821 tttcgtttat aattaagaat gattttatga aagggagtga aaatacatga aattctactc
    56881 ttatgactat gtactcagcc aaatcggtca gcaaaatggt atcatggttg gctttgggat
    56941 tgttctatta gctatgacag tttttttgct ttcaaggcat accatgataa aaagggaacc
    57001 gaatttcgtg agttggtcat gatttcagct ctggccttat ttagctctgc ttttggtcag
    57061 catcacgact tatcaaaaca atcaagtttc taacaataaa tttcaaactt cacttcattt
    57121 catcgaggtt gtttccaaag atttgggagt agacaagtca gaagtctatg ttaatacttc
    57181 cacaaacaca gatggcgcac ttatcaaggt gggagatcgc tattatcgtg ccctaaacgg
    57241 aagtgagcca gacaagtacc tgttagagaa agtcgaattg tataagacag acgcaattga
    57301 actggtggat gtgaacaaat gacacttaat tatatcgaaa ttttaatcaa actggtcttg
    57361 actctcaaat agctcaacaa caatgttcac tttgtgaaac gtttgattga tggtaagcca
    57421 actctcctta tcaaaaatgg gaatattgac ccataagcct gtcgttcagt tggtttgtct
    57481 gcatcggatg tagccctcaa acttcgtggc caagggattt tccagatgaa gcaagtcaaa
    57541 cgagctgtgc aagagcaaaa tgggcaactc atcgttgtgc aaatgggaga tgaaaattct
    57601 aagtatccag ttgtgactga cggtgtgatt caagtagatg tcttggaatc gattggtcgt
    57661 agcgaagagt ggttgcttga taacctcagt aaacaagggc atgacaatgt agccaatatc
    57721 tttattgctg aatatgacaa gggtgctgtt acagtcgtaa cttatgaata agaaaaacct
    57781 ggggtcttgt actcttcgaa aatctcttca aaccgcgtca acgtcgcctt gccgtatgta
    57841 ggttactgac ttcgtcagtt ctatctacaa cctcaaagca gtgctttgag cagcctgcgg
    57901 ctagtttcct agtttgctct ttgattttca ttgagtattg gcttcaggtt tccatttgca
    57961 atcagaaagg gattttatgt ccattattca aaaactttgg tggtttttca agttagaaaa
    58021 acgccgttat ctagtcggga ttgtggccct ggtcttggtt tccgttctca atctcattcc
    58081 tcctatggtt atggggcggg tcattgatgc catcacatcg gggcaattaa cccagcagga
    58141 cctccttctt agcctatttt acttgctact tgcagccttt ggtatgtact atttgcgcta
    58201 tgtgtggcgt atgtatatcc ttgggacctc ttattgcttg ggacagatca tgcggtctcg
    58261 cttgtttaag catttcacaa aaatgtcatc agccttttat caaacctatc ggacgggtga
    58321 tctgatggca cacgcaacca atgatatcaa tgccttgact cgtttagcag gtggcggtgt
    58381 catgtctgcg gtggatgcct ctatcacggc tctggtgact ttgttgacca tgctctttag
    58441 catctcatgg cagatgactc ttgttgccat tctcccccta cctttcatgg cctatgcgac
    58501 tagtcgccta gggagaaaga ctcataaggc ctttggcgaa tcccaagctg ctttttctga
    58561 actcaataac aaggtacagg agtccgtatc aggtatcaaa gtgaccaagt ctttcggtta
    58621 tcaggcagac gagttgaagt cttttcaggc agtcaatgaa ttaaccttcc aaaagaacct
    58681 gcaaaccatg aaatatgata gtctctttga ccctatggtt ctcgtgtttg ttggttcgtc
    58741 ctatgtttta acgcttttgg ttggctcctt gatggttcag gaagggcaga ttacagttgg
    58801 gaatctagtc acctttatca gctatttgga tatgctggtc tggcctctta tggccatcgg
    58861 cttcctcttt aatactactc agcgagggaa ggtttcttac cagcggattg aaaatctttt
    58921 gtctcaggaa tctcctgtac aagaccctga gtttcctctg gatggtattg aaaatgggtg
    58981 tttggagtat gccattgaca gctttgcttt tgaaaatgag gaaacactga cggatattca
    59041 ctttagtttg gcaaaagggc aaacactggg cttggttggg cagacaggct ctgggaaaac
    59101 gtccttaatc aagctcctct tgcgtgaata cgatgtggat aagggtgcca tttatctaaa
    59161 cggtcacgat attcgggact atcgtctgac agaccttcgc agtctcatgg gctatgttcc
    59221 tcaggaccag tttctctttg caacttcaat cctagacaat atccgctttg gcaatcctaa
    59281 cttgcccctt tcagcggtcg aggaagctac taagctagcc cgagtttacc aagatattgt
    59341 agacatgcct caaggatttg atacgctgat tggtgaaaaa ggagtcagtc tttctggtgg
    59401 tcaaaagcaa cggttggcta tgagtcgggc tatgatttta gaccctgata tcttgatttt
    59461 ggatgattcc ttatccgccg tagatgccaa gacagagtat gcgattatcg acaacctcaa
    59521 ggagacgcga aaggacaaga caaccattat cactgcccat cgcctcagtg ctgttgtcca
    59581 tgcagatttt attttagttc tacaaaatgg tcaaattatc gaacgaggca ggcacgaaga
    59641 cttgctagcg atggatggct ggtatgccca aacctaccag tctcagcagt tagaaatgaa
    59701 aggagaagaa gatgcagaat aaacaagaac aatgggctgt attgaagcgc ttgatgtctt
    59761 atctcaagcc ttatagactc ctgacctttt tggcactcag ttttctccta gcgacgacgg
    59821 tcattaaaag tgtcataccc ctcgtggctt cccactttat cgaccagtat ctcagcaatc
    59881 ttaaccaact agccgttacc gttttgctgg tctactatgg tctctacatc ctacaaactg
    59941 tagttcagta tgtaggcaat cttctctttg cgcgcgtgtc ttacagtatt gttagggata
    60001 ttcgtcggga tgcctttgcc aatatggaga aactgggcat gtcttacttt gacaagacgc
    60061 cagcaggttc tatcgtttct cgtttgacca acgataccga gacgattagt gatatgtttt
    60121 ctgggatttt atccagcttt atctcagcag tttttatctt tctgacaacc ctttatacca
    60181 tgttggtgct ggattttcgt ttgacggctt tagtcttgct ctttctccct ttgattttcc
    60241 ttttggtcaa tctctatcga aaaaagtcag tgaaaatcat cgagaaaacc agaagtctct
    60301 tgtcagatat caatagtaag ctggcagaga atatcgaggg aatcaggatt attcaggctt
    60361 ttaatcaaga gaagcgcctg caggcagaat ttgatgaaat caaccaagaa cacttggtct
    60421 acgccaaccg ttctgtagcc ttggatgccc tctttttgag acctgccatg agtttgctga
    60481 aacttctagg ctatgcagtc ttgatggcct actttggcta ccgtggtttt tctatcggga
    60541 taacggtcgg gaccatgtat gcctttatcc agtacatcaa ccgccttttt gaccccttga
    60601 ttgaggtgac gcaaaacttt tcaactctgc aaacggctat ggtttctgca ggtcgtgtct
    60661 ttgccctgat agacgagagg acctatgaac ctcttcaaga aaatgggcaa gccaaagtcc
    60721 aagaaggcaa tatccgtttt gaacatgtgt gtttctcata tgacggtaaa catccgattc
    60781 tggatgacat ttctttctct gttaataagg gtgaaaccat tgcctttgta ggtcatacag
    60841 gttcagggaa atcgtctatt atcaatgtcc tcatgcgctt ttatgaattc cagtcaggga
    60901 gagttctctt ggatgatgtg gatatcaggg atttcagtca agaagagctg agaaaaaaca
    60961 tcggtttggt cttgcaggaa cccttcctct atcatggaac tattaagtcc aatatcgcca
    61021 tgtaccaaga aaccagtgat gagcaggttc aggctgcggc agcctttgtg gatgcagatt
    61081 cctttattca agaacttcct caggggtacg actcccctgt ttccgagcgt ggtttgagct
    61141 tctctactgg gcaacgccag cttcttgcct ttgctagaac agtcgccagc cagcctaaaa
    61201 tcctgatttt ggatgaagcg acagccaata ttgactctga aacagaaagc ttggttcaag
    61261 cttctctggc gaagatgaga cagggccgaa caactattgc tatcgctcac cgcctttcta
    61321 ctattcaaga tgccaactgc atctatgtct tggataaggg acgcattatc gagagtggaa
    61381 cccatgagga actcttggct ctgggaggaa cctatcacaa gatgtatagt ttgcaggcag
    61441 gggccatggc cgatactctt tgaaaatctc tttaaaccat gtcagcttta tctgcaatct
    61501 caaagctgta ctttgatttt cattgagtac tagaaggaaa tccttcaaat tacagatttc
    61561 tttcaccgcc ttttccattt tgtggtataa tgaaaaatgt tgacaaatag tataataaaa
    61621 acaaaggaga acagcatgct gaaatgggaa gacttgcctg tggaaatgaa atcaagcgag
    61681 gttgagtctt actaccagct tgtctctaaa aggaagggtt cgctgatttt caagcgttgc
    61741 ttggactggg ttttggcctt ggtcttactg gttctgacct ctcccatctt tctcatcttg
    61801 agcatttgga tcaagttgga tagcaaaggg ccagtgattt acaagcaaga gcgtgtgacc
    61861 cagtacaacc gtcggttcaa gatttggaag tttcgtacca tggtgacgga tgcggataaa
    61921 aaaggaagtc tggtgacttc tgctaacgat agccgcatta ccaaggttgg aaatttcatc
    61981 cgacgtgtcc gtttggacga actgcctcag ttggtcaatg tccttaaagg tgagatgtcc
    62041 tttgtcggta cacgacctga agtgccacgt tatacagagc agtatagccc tgaaatgatg
    62101 gcaaccttgc tcttgcaagc agggattacc tctccagcca gcatcaacta caaggatgag
    62161 gacaccatca tcagtcaaat gacggagaaa ggtctgtcag ttgatcaggc ctatgtggag
    62221 catgttcttc ctgaaaagat gcactataac ctcgcctatc tccgagagtt tagtttcttt
    62281 ggggacatca aaatcatgtt tcaaaccgtg tttgaggtac taaaataaag tagtcataag
    62341 aaaatgagta cagataaaag gagcaaatca atgccaaatt acaatattcc attttcaccg
    62401 cctgatatca cagaagcaga aattgctgaa gtagcggata ccctgcgttc tggttggatc
    62461 acaacaggtc ctaaaacaaa agaactggag cgccgcttgt ctctttacac acagacacct
    62521 aagactgttt gtctcaactc tgcgacagcc gctctggagt tgattttacg cgttttggaa
    62581 gtgggacctg gtgatgaagt catcgttcca gccatgacct atacggcttc atgtagtgtc
    62641 attacgcacg tgggagcaac ccctgtcatg gtggatatcc aagcagatac gtttgagatg
    62701 gactatgacc tgcttgagca agctatcact gagaaaacta aggtgattat cccagtagag
    62761 ctcgcaggga ttgtttgcga ttatgaccgt ttgttccaag tcgtggagaa aaaacgtgac
    62821 ttctttactg cttcaagcaa gtggcaaaag gcctttaacc gtattgtcat tgtctctgat
    62881 agtgcccacg ctttgggatc tacttataaa ggacaacctt ctggttctat cgctgacttt
    62941 acttccttct cattccatgc cgttaagaac tttacaacgg cagaaggtgg aagtgcgact
    63001 tggagagcca atccagtgat tgatgacgaa gagatgtaca aggaattcca aattctttcc
    63061 cttcacgggc aaactaagga tgctcttgcc aagatgcaac tggggtcatg ggaatacgat
    63121 atcgttacac cagcctataa gtgcaacatg accgatatca tggcttcact tggtttggta
    63181 caattggacc gctatccaag tttgttgcaa cgccgtaagg acattgtgga ccgctatgat
    63241 agtggttttg caggttctcg catccatcct ttggcacaca agactgaaac tgtcgaatct
    63301 tcacgccacc tctacatcac ccgtgtagaa ggagcaagcc tagaagaacg caacctcatc
    63361 atccaagaat tggctaaagc aggaattgca agtaatgttc actacaaacc gcttcctctc
    63421 ttgacagcct ataagaatct tggatttgat atgacgaact atcctaaagc ctatgccttc
    63481 tttgagaatg aaattaccct ccctcttcat actaaattaa gcgatgaaga agtagactat
    63541 atcattgaga ctttcaaaac agtttctgaa aaagtgctaa ctttatcaaa aaaatgacaa
    63601 actacagtca agcgaaagtg atcctgtccc taaaaagtct aattgagtgt aaaaactgtt
    63661 gttttcaatt gataatagtt tacacctgta gttgaggcct ctttctcctc agagagagaa
    63721 tttttatagg attttccttt cttgtgggag tcccgtggtt tgaaataaga tgtgagcaat
    63781 ttggtgtagc atttagaatc cttactagac atcatttaga aaatctagtg tcttgttcta
    63841 gttttcaatt caccctattt tttgaaagac gtgagtttcc atgagtgaga ttgtggaaac
    63901 tcgcgtcttt tttttgtttt cagaatattg ttcaaagttt tgtgcctgtc tttcatgttc
    63961 tagtcattct tttgcatgat agaatttata acatgttgat attataataa tgcaaatatt
    64021 ctatatgttt agtgatgctt gctatacatc attagatctc ctgcgagaca atctataaaa
    64081 cacttgtcta ctattaccta tatgccctat tccagtattt tagaagcact gcatctattt
    64141 ttatcgaggt taaatctagc ttttatagaa ggtctattta agaaatatat tgtagtgttt
    64201 tagtttcaat ccgccatatg agcgatattc atgtaaatat ccctggcgaa tgcttgtatg
    64261 acaaggtatt tgttctttca tttataattt acaacatatc aataaattta aatatagtaa
    64321 atgggatatt ttatattcaa gctaagaaag atagcatcac ttttgaatgg aaggctaaag
    64381 agcaaactag gaagttggct atagatagct caaaaccctg ctttgaggtt gtagatatag
    64441 taaaaggaaa taagaatagg acaaatcgat cgggacagtc aaatcgattt ctaacaatgt
    64501 tttagaagta gaggtgtact attatagttt cagtctacta tagaactgac caagtcagta
    64561 acctagactt agggcaaggc ggcactgacc tagtttgaag agatttccga agagtataaa
    64621 ttttaatatt ttcttgtgtt attccttgac aattcaattt ggaaaatata tgataaagat
    64681 aatgacagcg gtgtcaatct atctatttta agaaaagtaa taatcaattg ttaaaaatag
    64741 taaaaaaatt ggaggttctg atgaaatatt ttgttcctaa tgaggtattc agtattcgta
    64801 aattaaaggt ggggacttgc tcggtactat tggcaatttc aattttggga agccaaggta
    64861 ttttatcgga tgaagttgtt actagttctt caccgatggc tacaaaagag tcttctaatg
    64921 caattactaa tgatttagat aattcaccaa ctgttaatca gaatcgttct gctgaaatga
    64981 ttgcctctaa ttcaaccact aatggtttag ataattcgtt aagtgttaat aatatcagct
    65041 ctaatggtac tattcgttcc aattcacaat tagacaacag aacagttgaa tctacagtaa
    65101 catctactaa tgaaaataag agttataagg aagatgttat aagtgacaga attatcaaaa
    65161 aagaatttga agatactgct ttaagtgtaa aagattatgg tgcagtaggt gatgggattc
    65221 atgatgatcg acaagcaatt caagatgcaa tagatgctgc agctcaaggg ctaggtggag
    65281 gaaatgtata ttttcctgaa ggaacttatt tagtaaaaga aattgttttt ttaaaaagtc
    65341 atacacactt agaattgaat gagaaagcta caattctaaa tggtataaat attaagaatc
    65401 acccttccat tgtttttatg acaggtttat ttacggatga tggtgcgcaa gtagaatggg
    65461 gcccaacaga agatattagt tattctggtg gtacgattga tatgaacggt gctttgaatg
    65521 aagaaggaac taaagcaaaa aatctaccac ttataaattc ttcaggtgca tttgctattg
    65581 ggaattcaaa taacgtaact ataaaaaatg taacattcaa ggatagttat caagggcatg
    65641 ctattcaaat tgcaggttcg aaaaatgtat tagttgataa ttctcgtttt cttgggcaag
    65701 ccttacccaa aacgatgaag gatgggcaaa tcataagtaa ggagagcatt cagattgaac
    65761 cattaactag aaaaggtttt ccttatgcct tgaatgatga tgggaaaaaa tctgaaaatg
    65821 tgactattca aaattcctat tttggcaaaa gtgataaatc tggggaatta gtaacagcaa
    65881 ttggcacaca ctatcaaaca ttgtcaacac agaacccctc taatattaaa attttaaata
    65941 atcattttga taacatgatg tatgcaggtg tacgttttac aggattcact gatgtattaa
    66001 tcaaaggaaa tcgctttgat aagaaagtta aaggagagag tgtacattat cgagaaaacg
    66061 gagcagcttt agtaaatgct tatagctata aaaacactaa agacctatta gatttaaata
    66121 aacaggtggt tatcgccgaa aatatattta atattgccga tcctaaaaca aaagcgatac
    66181 gagttgcaaa agatagtgca gaatatttag gaaaagtatc agatattact gtaacaaaaa
    66241 atgtaattaa taataattct aaggaaacag aacaaccaaa tattgaatta ttacgagtta
    66301 gtgataattt agtagtctca gagaatagta tattcggtgg taaagaagga attgttattg
    66361 aggattcaaa gggtaaaata accgttttaa ataaccaatt ttataattta tccggtaagt
    66421 atatatcatt catcaaatct aatgcaaatg ggaaagaacc tgttatacgt gatagcgatg
    66481 gtaatttcaa tattgtaacg gagaatgggc tttacaaaat tgtaacaaat aatttaagtg
    66541 ataaaaacga aaaagaaaaa aacaaagagg aaaaacaatc taattcaaat aatgtaattg
    66601 atagtaacca gaagaacgga gagtttaact caagtaaaga taatagacaa atgaatgaca
    66661 agatcgacaa taaacaagat aataagacag aagaagtaaa ctataaaata gttggagatg
    66721 gcagagaaac tgaaaatcat attaataaat ctaaagaaat agtagatgta aaacaaaaat
    66781 taccaaagac tggttcgaac aagattatgg aactattctt aacagtgaca ggaattggtt
    66841 tacttttgac actaaaaggg ttgaagtatt atggtaaaga taaataaaat ttgttcgata
    66901 caaggaagtt ccgtagaaaa tgaggatatt gtaggttcac aaaatcagta tttttggatt
    66961 attggtggag ctacagattt atataattct aaagaggaga taggttattc agtctcagaa
    67021 gttgtacata ttttatcaga aagtttgtcg gttaattgta aagaatcaaa aactcttaaa
    67081 caaatatttg aaactgcttt actcgaggtt aaagatgaaa tcggtttaaa ctcatatgaa
    67141 ttaacagagt atagtaaaat gaaataataa tagaacaaat caatcaggac agtcaaatcg
    67201 atttctaaca atgttttaga agtagaggtg tactattcta gtttcaacat actatattat
    67261 cgcttaccaa tatttgctaa actttcagaa aaaaagttgg agtatatgat gctaggtgac
    67321 tgcgtcatgt tagtaaacga aatggaaata actgatcata gagtagataa cttatttgaa
    67381 aaagggaaaa atgagataaa agatccatgt agtagattta gcaataggac atataaaagc
    67441 tttagaaaaa gtatctgaaa aaacagatgt ttatatctat aacctatgct cgggagaagg
    67501 cactagtgta ttacaacttg taaatacatt tgaaagtgtt aataagatcc ctattcctta
    67561 taaaatagtt ccaagacgtt caggagacgt tgcaacttgt tatgcaaatg cagacaaaga
    67621 gcatataagg aattaaattg gaggacaaca aaatcgattg aagacatgtg tagagataca
    67681 tggaattggc aatcaaaaaa tcccaatggc tataattgat gatactgtct atatgagtgc
    67741 tgtattttgg aaaaattact taacctttta atgaaatgca tatttaatga aagataaatt
    67801 aaaaaaaatg tttgacagcg cttgacaaag gaaacggttt cattgtataa tgtaaacata
    67861 gtgacaccga tgtcaaatat aaaaaagaag gtctttatat gaaaaactta acaaaaatta
    67921 agttcaaaga gaatggggaa tttaatcatt tccctgggaa tacagttgta gcaaatcttt
    67981 atactaaaca agatttgatg gaagttgttg atattattca atcacgttat agagaattac
    68041 catttatcga taagtttact ttaactccaa ggaattctat tcacatgact gtaattgaat
    68101 tgttgtgcca tgaaaatcgt gaaacggagt tttggagcag taatcttcct ctagatacac
    68161 ctttacagga aatacatgat tactttgcta aacaacttga aatttttcca ttgttggatg
    68221 aagaaattca tatgcgtata actgaaatgg gaaaacaaaa catactagtt gaacctgcag
    68281 atgaagcttc tgcaaagaga ttagaagaaa ttcgtactta tgtctcagaa aaagcaggtg
    68341 tttgtttccc taatcatgat agatatcaat tccatatttc aattgggtat cttcggattc
    68401 ctctaaccga agaggaggaa gaagagttta ctaaagtcag agcagaatta actgaaattt
    68461 tattagagaa gattccaact attactgtaa accgtattga ctatactgta tttgaagata
    68521 tgagacaatt tgttccatat cacgaaaaat ttaaataaaa taataaaaaa ggagaactta
    68581 tcatgaaaaa aatgaaagtt tggtctactg tacttgcaac gggagttgct cttactacac
    68641 ttgctgcttg ctctggaggt tcaaattcta cgactgcttc ttcatctgaa gaaaaagctg
    68701 ataaaagtca agaattagtt atctattcga actcagtctc aaatggtcgt ggtgattggt
    68761 taactgctaa agcaaaagaa gctggtttta atataaaaat ggttgatatc gctggcgctc
    68821 aattagcaga ccgtgttatt gctgagaaga ataatgcagt tgcagatatg gtatttggaa
    68881 ttggtgctgt tgactcaaat aaaattagag atcaaaaatt actagtacag tacaagccta
    68941 aatggttaga taaaattgat caatctttat cagataaaga taattattat aatcctgtga
    69001 ttgttcaacc attagtttta attggggcgc ctgatgtaaa agaaatgcct aaagattgga
    69061 ctgaattagg tagtaagtat aaaggtaaat attcaattta tggtcttcaa ggtggtacag
    69121 gacgggcaat tctagcaagt atcttagttc gttaccttga tgaaaaagga gatttaggcg
    69181 tatcagaaaa aggatgggaa gttgcaaaag aatactttgc aaatgcctat actcttcaaa
    69241 aaggtgaaag ctcagttgtt aaagcgttag ataaagaaag cccaattcaa tacggtatga
    69301 tctggggttc tggagcgtta attggacaaa aagaacaaaa tgttgaattc aaagttatga
    69361 ctcctgagat tggtgtacca tttgtaactg aacaaactat ggttttaagc actagtaaaa
    69421 aacaagcgtt agctaaagaa tttattgatt ggtttggtca atcagaaatt caagtagaat
    69481 atagtaaaaa atttggatct attcctgcaa ataaagatgc cctaaaagag ttacctgaag
    69541 atacgaaaaa atttgttgat caagtgaaac cacaaaatat tgactgggaa gctgttggaa
    69601 agcatttgga tgaatgggta gaaaaagctg aattagaata cgtacaataa gaaataagag
    69661 ttatttttta tgtccaagtc tctctattat ttctaaattt aaggaagaaa taaagagagg
    69721 cttttggttt agtaatagag ggagttagtg agatgattaa atttgataat attcaaatta
    69781 aatatggtga ttttgttgca attgataatc tgaatttaga tatacatgaa ggggaattct
    69841 ttacatttct tgggccttca ggatgtggta aatcaactac tttgagagca ttggtaggtt
    69901 ttttagatcc atcatcagga agtattgaag ttaatggaac agatgtcact catttggaac
    69961 ctgaaaagcg tggaattggt attgtatttc aatcttatgc gctatttcca actatgactg
    70021 tttttgataa tattgcattt ggtttaaaag ttaagaaggt agctccagat gttattaaag
    70081 ctaaagtatc agcagtggca gcaaaaatta agatctctga tcaacagtta cagcgtaatg
    70141 tatcagaatt atctgggggt caacaacaaa gggtagcatt ggctcgtgct ctggttcttg
    70201 aacctaaaat tctttgtcta gatgaaccat tgtcaaacct tgacgcaaaa ttacgtgtag
    70261 atttgagaaa agagttgaaa agacttcaaa aagagttagg tattactact ttatatgtta
    70321 ctcatgatca agaggaagcc ttgactttat ctgatagaat tgcagtcttt aacaatggat
    70381 acatcgaaca ggtcggtaca ccagtagaga tttatcataa ttctcaaact gaatttgtat
    70441 gtgattttat tggagatatt aatgttttga ccgatgaaac agtccacgaa gtattattga
    70501 aaaatacaag cgttttctta gaggataaaa aaggatacat tcgattagag aaagttcgat
    70561 tcaatcgtga aactgaacaa gattttattc taaaagggac aattattgat gttgagtttt
    70621 ctggagttac aattcactat acaataaaag tttctgaaag tcagattctt aatgtaacaa
    70681 gtattgatag tcaggctgct attagatctg tcggagaaag tgtggaatta tttatcacac
    70741 catcagacgt tctgcaattt taaggaggtg cagtatgcgt cataaattaa atttaaaaga
    70801 ttggcttatt cgtttaggat taatctggtt cttagtaaca tttattattt atccaaactt
    70861 tgatctagta gtgaatgtat ttgtaaaagg aggagaattt tcccttgatg ctgtacatcg
    70921 tgttctaaaa tctcagaggg cacttcagag tattatgaac agttttaagt tagcattttc
    70981 actcattatt acagttaatg tcgtaggtat tctttgtgtt ctatttacag agtactttga
    71041 tattaaaggt gctaaaattt taaaattagg ttatatgacc tctttaattt atggaggagt
    71101 ggttttagcg actggatata aatttgtcta tggtccttat ggattgatta caaaattttt
    71161 acaaaatgtt atcccttctt tagactctaa ctggtttatt gggtatggtg cagtcttatt
    71221 cattatgaca ttttcaggaa ctgctaatca tacattgttt ttaacaaata caattcgaag
    71281 cgttgactat cacactattg aggctgctcg aaatatggga gcaaaaccat ttactgtttt
    71341 ccgaaaagta gtgttaccaa ccttaattcc aactctattt gcacttacta ttatggtttt
    71401 tcttagtggt ttatctgcag tagcagcacc catgattgtt ggtggtaaag aatttcaaac
    71461 tataaatcca atgattatta catttgcagg gatggggaat tctcgtgatt tagctgcctt
    71521 acttgcaatt attttaggta ttgcaactac aattttgctt actatcatga ataagataga
    71581 aaaaggtgga aattatattt ctatctctaa gactaaagcg cctcttaaaa aacaaaaaat
    71641 tgcgtctaag ccttggaata tcattgctca cattgtagca tatggattgt tcacagtttt
    71701 catgcttcca ctaattttta tagtattata ctcatttaca gatccagttg caattcaaac
    71761 aggtaactta acattatcaa actttacttt agaaaattat cgcttattct ttagtaatag
    71821 tgcggcattc tctccattct tggtcagctt tatttattct attattgctg cgacaacagc
    71881 aacaattctc gcagttgtat ttgctcgtgt tgtcagaaaa cataaatctc gttttgattt
    71941 cttatttgaa tatggtgctc tacttccttg gttactacca agtacacttt tagcagtaag
    72001 tttattattt acttttaatc agccacaatt tcttgtcttg aatcagattt tggtaggtag
    72061 tttggtaatt ctacttattg catatatagt tgtaaaaatc ccattttctt atagaatggt
    72121 acgtgctatt ttatttagtg ttgatgatga gatggaagat gcagcaagaa gtatgggtgc
    72181 ttcacctttt tatactatga tgaaggttat cattccattt attttaccgg ttgttctctc
    72241 tgttattgct ttaaacttta actctttatt aactgacttc gacttatctg tattccttta
    72301 ccatccccta gctcaaccat taggtattac gattcgatct gcaggtgatg aaacagcaac
    72361 atctaatgca caagctctgg tatttgttta tacaattgtt ctgatgatta tttctggaac
    72421 ggtattatac ttcacacaaa gaccggggcg taaagtaagg aaataatcat gacagccact
    72481 agtcttgggt tatcaaatat tgaaatagtt gtcaggattg ttttatcagt agtcattggt
    72541 agtataattg gtttagagag agggagcaaa tcccagcctg caggcatccg aacttatagt
    72601 attgtttgtc tagctgcatg tttgattatg atgacgaatg aatacgtatc ttataaattt
    72661 gggacaggag atcctacacg attaggagct caagttatat caggtgtggg ttttctaggc
    72721 gctggaacga ttcttattac agataaaaag aaaattacag gtctgacaac tgcagcaggc
    72781 atttgggctt cggcaggaat tggattagct attggagtag gtttttatga gggagctctt
    72841 ttagtagcca tttctgtttg gggtgtgata tccatgttcc aaccactaaa aaaatatctg
    72901 caaaatcgtt ctaaaatgat tgaattgtat atagtagtta aatctacaga agcctataat
    72961 cgtgtattgg tttattgtgc agaaaatggt atcagaatga ccgattcaag aacagcgttt
    73021 ggagatgtta attctgacag aattgaatac tttgatgttc cggacaaaaa aatagcgtca
    73081 tttattactc tggaattatc aggtagattt gaacatcttc gactgatgga agaaattgct
    73141 aatattgtag gtgttattta tgtcgaagaa attagctgaa atttagtaaa caaagggaca
    73201 gatatttttg tccttttgtt ttttagatgt tttaatcatc taatttttga gtagattttt
    73261 gctcagaggt ttttatgaaa gattataaaa tcaattttga tttaggtaaa atagaatatt
    73321 ttgataataa ttgtttgata caagtataca aatttatttc tttttatgat atttgtgaaa
    73381 tggtgtttgc ctttcattta cctcctgatg agttgataac aaatgttatc tttaaagaaa
    73441 aaattaactc tatgttaaaa tgttaaattg acaggctatt atatgttttt ataaatccta
    73501 cacattttac tgaaaaagtt aatctacaat tttatggtag ttttttctca tatgaattta
    73561 tttgtcgtga agttggaaac attcttaaaa ataaaggtgt gaaatgcaat ttaaactttt
    73621 ttgaagggaa agaatatttg taaaattaat tttgtgaatt tgtggatctt aaataattta
    73681 ctaaattctc ttgttaaaaa aaattaaata ttgtatagta atattagaat gttcgtaatg
    73741 gaggactgaa atgaaaaata taaatgggaa aaaggtaact atttatgata ttgcacgttt
    73801 atcaggtttt tctccaaaaa cagtttcacg agttattaat ggtggagtaa atgttaaaga
    73861 agaaacttat caagcgattc aaaaagttat agaggaattg tcgtatattc caaatgcgta
    73921 tgcaaaaaat ttaactaaaa aagaagctat aaatatattg atttctgtaa aaaaaatcga
    73981 ctcttttcct ttaatttggt ttcatacgct gttagataaa gtgttacgga cgtgtaaaga
    74041 atttggtgtt aatgctatag ttgagtactt tggagaggag gatacaatta gtaattcaat
    74101 tatatcaagc acaggtagcc tagtagatgg tgttattgtt ttttatgaaa gtgtagatga
    74161 tatcagaatt cagtatttaa agaagaacca tatgcctttt cttgttttcg gtgaatctca
    74221 aacgtctgga gtagtctatg tatctaataa taattttcaa gctacttatg atatgatgaa
    74281 agctgtaact gaagaaaaat ttaaaaatat gtggttgctt atgggaggag aatcccatgt
    74341 taataaggat cgtgaaagag gtgtgcgttc ttttctgaat gataaaaatt actttatgga
    74401 tttaaaagtc atttatggct tatctacaat tgattcagtt tattcttatg caatgcagca
    74461 cttgactacc caaaattatc cggacattat ttttgtttca ggagatgaaa aggttcaggg
    74521 cttgattcgt gcgtgctatg agaaaggaat tcttattcca gatgatattt ctatcattgg
    74581 atttgataat attcctattt ctcagtatta tactccagct ttgtctacaa ttgctcccaa
    74641 ttatgttaaa ttggctaaag aaatgataga aggtgtttta gcaattatta aaggggaaag
    74701 tgtcacatct gttgaagttt ctcctaaatt tgttaggaga cagagtttct agtattgttt
    74761 aattcttgaa aatcctagtg gaaaagatgg agtgttctaa aataagttct gtttagcctc
    74821 cattcagttt ctattgagtt ggatccaatt tctaacgagt gggacatgtt catgttcgat
    74881 ctaaggaaga catggtcaca ttcgaatgat attttcaaaa aaatcgtaaa aaagtcttga
    74941 caaagaaaaa acaaagtatt aaaataagtt caacaaatca gaaaagtaac tatttttgat
    75001 cttcagggag cctgtggtga ttgtgaatag gtggttggaa gtagtgaaag tgggctgatt
    75061 ttgaaaatga atttgaaaca atgaaaattc ggtgcgcaca ccttacagtg cagcttgttg
    75121 ttaaacaagg cagagatgta aagggatagt ccctttataa ttgaggtggc atcgcgttac
    75181 caacgccctc acacggaagt atattctgtg tgtgggcttt tttctatccg tcgtttggtt
    75241 tatcttttat tagggcctta agtcgctttg atgaacttga gttctatcta cagctccttg
    75301 cctactacta aaagcaaaca aaaaggctgg actaatacga aaaaagctag taatactcaa
    75361 tgaaaatcaa agagcaaact aggaaactag ccgcaggctg ctcaaaacac tgttttgagg
    75421 ttgtggatag aactgacgaa gtcagctcaa aacactgttt tgaggttgca gatagaactg
    75481 acgaagtcag taaccatacc tacggcaagg cgacgttgac gcggtttgaa gagattttcg
    75541 aagagtataa aggtgtaccg agatgaacat ctcttcatca atgtctctgg tcgtggaggc
    75601 aaggacctag ctgcgattgc agactactag aagctaaaaa ataatagatg gaaaaattac
    75661 agttctttct ctcacagaga gcttgtggtt gctgaaaaca agcagagaaa gctgtaaagt
    75721 tgggttcatc tgaaacgaga gaagaaaaca tcattctcaa gggagtgccc tttatcgcac
    75781 agcctgttac aggagatatc tgagacagga atgagagata ggagaaatcc tataattgag
    75841 gtggcaccgc gaatttcgtc ctcacgcaag ttattttgcg tggggatttt tcatacagtc
    75901 gctacgaact agaattagaa ctgaaaggga aattacaatg gaacgaatca ttcatggaga
    75961 tgtcttatca ccaatcttgg cttatatgcg cttaaagggg caacacaagg ttatcttaga
    76021 gagtattccg agagacaagg aaacagctcg tttttctatc ctagcctata atcctgtttt
    76081 tgagattaag tttgaaaatg gagttcttta tcaaaatggt caagtgattg atcgggatcc
    76141 cttggatttc ctttatgaag tgattcataa gagtcagcac cattcagagc taccttttgg
    76201 tggtggagcc attggttttg tgggttacga tatgatttcg ctttatgaag aaattggtca
    76261 aatccctgag gatacaattg ggacgccaga catgcatttc tttgtctatg agagctatat
    76321 agtctttgac cacaagaagg agaagataca tgtcatagag gatgcacttt atagtgagcg
    76381 cagtcaagag gccttggaaa aatccttgaa ccaagtgctt gaggaattac gcattcctgc
    76441 tccaaatgaa tttgaagact tggatttatc accacttgac ttcaaaccgc atatcgctcc
    76501 acataagttt gaggtaatgg tagaaactgc tcgcgacttg attcgtaatg gtgatatgtt
    76561 ccaatgtgta ctcagccagc gtttctcagc agaagttact ggaaatccat ttgacttcta
    76621 cagaaatctc cgcgtgacta atccttctaa ttacctttat ttctatgatt ttggggatta
    76681 tcaaatcatc ggagctagtc cagaaagttt ggtttctgtc aaaaatggca tcgtgacaac
    76741 caatccgatt gcagggacgc gaccaagagg ggctacggat gaagaagaca aggccttggc
    76801 gactgacctc ctctctgatg agaaggaaac agcagaacat cgaatgttgg tagacttggg
    76861 gcgtaacgat attggccgca tctctgaaac ggccagtgtc caagttacta agtatatgga
    76921 ggtggagctc ttccgctacg tcatgcattt gaccagtgtg gtcaagggac gtttgcttgc
    76981 agaactcact gccatggatg ccttgaaagc aacgcttcct gctggaaccg tttctggagc
    77041 accaaaaatt cgagctatga gacgcatcta tgaactggaa acggaaaaac ggggcgtata
    77101 tgcaggagca atcggctact tgtctgcgac gggtgatatg gatttggcca ttgccatccg
    77161 aaccatgatt ctcaaaaatc aaagagccta tgtgcaggct ggggcaggga ttgtctacga
    77221 ctctatcgcc caaaacgaat accaagaaac cattaacaaa gcaaaatcta tgactagaat
    77281 tggagaacta agaccatgat tttattgatt gacaactatg attcttttac ctataacttg
    77341 gcccaataca ttgggaattt tgcagaagtt caggttctga gaaatgatga ttccaagctg
    77401 tatgaagaag ctgaaaaagc agatggtctg gtcttttctc ctggtcctgg ttggccagtt
    77461 gatgctggaa agatggaaga catgatttgt gattttgcag gcaagaagcc gattctaggg
    77521 atttgtttgg gtcaccaagc cattgcagaa gtctttggtg gtaagctagg tttggctcca
    77581 aaagtcatgc atgggaaaca gagcaatatc aactttgaag cgccatctgt tttgtatcaa
    77641 ggtattgagg atggacgtgc ggtcatgcgt tatcacagta ttttgattga ggaaatgcca
    77701 gaagactttg aagtgacagc tcgttcgact gatgaccaag ccatcatggg gattcaacat
    77761 aaaaacctac cgatttatgg cttccagtac catccagaga gcattggaac gccagacggc
    77821 ttgtcttcta ttcggaattt tatcgagaag gttgtaaagt gaggaaacta ggatgaaaga
    77881 gattattgaa aaactagcaa aatttgaaaa tttatcaggt gtggaaatga cggatgtcat
    77941 tgagcgtatc gtaactgggc gtgtaactga agcgcagatt gcttctctcc tcttagctct
    78001 caagatgaag ggggaaacac ctgaagaacg cacagccatt gcccaagtca tgagaggaca
    78061 tgcccagcat attccaactg agattcatga tgccatggat aactgtggta caggtgggga
    78121 caagtctttc agttttaata tttccacaac tgcagccttt gtcttggctg gtggcggtat
    78181 tcacatggcc aagcatggta accgctcgat ttcttctaaa tctggttccg cagatgtcct
    78241 cgaagccttg ggaatcaatc ttgatctcaa accagctgaa ctaggtaagg tctttgataa
    78301 aactggaatc gtctttctct tcgctaaaaa tatgcaccca gctatgaaat acatcatgcc
    78361 agctcgtttg gaattgggaa ttccaacgat tatgaacttg actggtccac tgattcatcc
    78421 aatggcttta gaaacacagc ttcttggaat tagtcgtcca gaactcctag aaagtacagc
    78481 tcaggttttg aaaaatatgg gtcgcaaacg tgccatcgtg gttgctggac cagaagggtt
    78541 ggatgaagct ggcttgaacg gaacaaccaa gattgcactt cttgaaaatg gcgaaatcag
    78601 cttgtcaagc tttactccag aggatttggg aatggaaggc tatgctatgg aagatattcg
    78661 tggtgggaat gctcaggaaa atgcagaaat tttgcttagc gttctgaaaa acgaagcaag
    78721 tccattcttg gaaacgacag tcttgaatgc tggtcttggt ttctatgcta atggtaagat
    78781 tgatagcatc aaggaaggag ttgccttggc ccgtcaagtg attgctagag gcaaggccct
    78841 tgaaaaactc agactgttac aggagtacca aaaatgagtc aggaattttt agcacgaatc
    78901 ttagagcaga aggcgcgtga ggtggagcag atgaagctgg agcaaatcca gcctctgcgc
    78961 cagacctatc gcttggcaga atttttgaag aatcatcagg accgcttgca ggtaatcgct
    79021 gaggtcaaga aagctagccc tagtttggga gatatcaatc tcgatgtgga tattgtgcaa
    79081 caggcccaga cttatgaaga aaacggagca gtgatgattt cggtgttgac agatgaagtt
    79141 ttctttaaag gacatttgga ttatctacgg gagatttcca gtcaggtaga gattccgacg
    79201 ctcaacaagg actttatcat cgatgaaaag caaatcatcc gcgctcgcaa tgcaggtgcg
    79261 acagtcatct tgctcattgt ggcagccttg gcagaagaac gtcttaagga actttacgac
    79321 tacgcgacag tgcttggtct ggaagtcttg gtggaaactc acaatctagc tgaactagaa
    79381 gtggctcaca gacttggtgc ccagattatc ggggtcaata accgcaactt gaccaccttt
    79441 gaggtcgact tgcagaccag tgtagacttg gctaaacatt tcaaagatga ttgcttgtac
    79501 atttctgaat ctgctatttt cacaaggcag gatgcggaac gactagcccc atactttaac
    79561 ggaattttgg tagggacagc tcttatgcag gcagaaaatg tggtccagag aatcaaggag
    79621 ttgcagattg acaaaggtta aaatttgtgg actatcgacc gaagaagcgg tggaaacagc
    79681 cgtttcagca ggagccgact acatcggttt tgtctttgca cctagtaaaa gacaggtgac
    79741 tttagaagag gcagctgagt tggcaaagct tattccttca gatgtgaaaa aggttggagt
    79801 atttgtttca ccaagtcggg tagaactgct ggaagcgatt gacaaagttg gcttggactt
    79861 ggttcaagtt cacggtcagg tggcagatga tttatttgag aatttgcctt gtgccagtat
    79921 tcaggctgtg caggtagatg gaaatgggca tgtccccaat tctcaggcag attatctact
    79981 ctttgatgcc cctgtggcag gaagtggcca gccctttgat tggggtcaac tggatacgac
    80041 tggactagca cagcccttct ttatcgcagg tggccttaat gaagataatg tagtaaaagc
    80101 aattcaacat tttactccct atgcagtaga tgtatcgagc ggagtggaga cagatggaca
    80161 aaaagatcat gaaaagatta gaagatttat agagagggta aagcatggca tatcaggaac
    80221 caaataaaga tggattttac ggaaaattcg gcggacgttt tgtcccagaa acattgatga
    80281 cagcagtttt ggagttggag aaggcctatc gtgaaagtca ggcagaccca agtttccaag
    80341 aggaattaaa ccaactcttg cgccagtatg tggggcggga aactcctctt tactacgcaa
    80401 aaaacttgac ccagcatatt ggcggagcca agatttatct caaacgggaa gaccttaacc
    80461 atacaggagc ccacaagatt aacaatgcct taggacaagt ttggcttgcc aaacgcatgg
    80521 gtaaaaagaa aattatcgca gaaaccggtg ctggtcagca cggtgtggca actgcaactg
    80581 ctgcggccct ctttaacatg gaatgtacca tctacatggg tgaggaagat gtcaaacgcc
    80641 aagccctcaa tgtcttccgc atggagcttt tgggagccaa ggtcgaggct gtaacagatg
    80701 gttcgcgcgt gctcaaggat gcggtcaatg cagcccttcg ttcatgggtg gctaatatcg
    80761 acgataccca ctatatcctt ggttctgcct tggggcctca tccatttcca gaaatcgttc
    80821 gtgacttcca aagtgtcatc ggtcgcgaag ctaaacaaca gtatcgcgat atgacaggtc
    80881 aaaatctgcc cgatgctcta gtagcctgtg ttggtggtgg atctaatgct attgggctct
    80941 tccatccctt tgtagaagat gagtcagtag ctatgtatgg aactgaagca gcagggcttg
    81001 gtgtggatac agagcaccac gctgctacct tgaccaaggg tcgtccgggt gttcttcacg
    81061 gttctctcat ggatgtgctc caagatgccc atggtcaaat tcttgaagcc ttctctatct
    81121 cagcaggttt ggactatcct ggtattggtc cagaacattc tcactaccac gatatcaaac
    81181 gtgccagcta tgtccctgtg acagacgaag aagccttgga aggattccaa ctcttgtctc
    81241 gtgtggaagg gattatccca gccttggaat ctagccatgc tatcgctttt gcggtgaaat
    81301 tggccaaaga acttggacca gaaaagtcta tgattgtctg cctatcaggt cgtggggaca
    81361 aggatgtggt tcaagtcaaa gaccgcttgg aagcagatgc agcaaagaag ggagaagctc
    81421 atgcctaaga cactaacaga aaaattgaat gctattaaag cagctggaaa aggaattttt
    81481 gttccctata tcatggctgg tgaccacgag aaaggtttgg acggtcttgc tgaaacaatt
    81541 cactttttag aagatttggg tgtctctgca attgaagtgg gtattccctt ttcagaccct
    81601 gttgcagatg gacctgttat cgaagaagct ggcttgcgca gtttagccca cgggacctct
    81661 acccaggctt tagttgaaac cttgaaaacc attgaaacag agattccact ggtcatcatg
    81721 acctacttca accccctctt tcagtacggt gtggagaact ttgtcaaaga tctggctgat
    81781 acagctgtga agggcttgat tatcccagac ttgcctcatg aacatgccaa ctttgtagaa
    81841 ccatttttgg cagatacaga tatcgccttg attcctttag taagcttgac cacaggaatt
    81901 gagcgccaga aagagttgat tgaaggggcg gagggattca tctatgccgt tgccatcaat
    81961 ggagtgacag ggaaatcagg caattaccgt gcagatttgg acaagcactt ggcgcaactt
    82021 catcaagtgg ccgacatccc agtcttgaca ggttttggtg tatctagtca agccgatctg
    82081 gaacgcttca atgcggtgtc agatggtgtt atcgtcggtt cgaaaatagt aaaagctctc
    82141 caccaaggag agccgattca ggactttatc aaacaagcag tagcttacca aaaataatca
    82201 aacaagtagc aagtaagagg aaaggcacga aaggaagtct ttcctttttc ttttgcagga
    82261 gaaaggccag gatacccgtc gcagaagcga actgaatcaa gatcagtaac tccgttacgc
    82321 taaagacgag agcacaagaa gctaaaaaaa ggaaatcccc tgcacccatg cggatatcga
    82381 taaaatgagc caaaattcca agtatgagga aggagaccat gaccagattc cagccagagg
    82441 aagctattag gattaggtgg aaagtcatcc agaccagtaa gggatattcc tgatggtgaa
    82501 agtcgtagat acccaaggtc aaaccagcgg tgattaggac gacttgcccc aaggaaagca
    82561 actcccaaga gtaaagcaga aagaggagtc ctaagcctag ttcaaagagg gcataccaga
    82621 caggatagcg gaccttgcag tagcgacagc aaaagcgatt gaagacctgt gagagaatcg
    82681 gaatcaaatc taagggacgc aagcgagtct gacaggaatc gcagtgactg actgaactga
    82741 taatggattg ctctggaaaa cggtcaatga ccaaaccaag aaaggaagcg agaatgctcc
    82801 cgacgagaaa aaaataaaaa tcaatcatac ttatctattc gtaaaaaatg ggagaaatag
    82861 tataatggag aaacatagat aagatggtga ggaaaagatg acaattcgtt ttgaagaaaa
    82921 ggtgagtata gaaaacgctc aatttgtatg ccagtggtcc aactccctag gcaaatcctt
    82981 tcaagaacaa tggatgggac caaggattcc ttttctactg acccttcaag ccttggaagg
    83041 agtcttttca atctttgatg aacaagagtt tgtgggattt atccagaaaa tcaggctaga
    83101 agacagcaat cttcatatcg ggagattttt tatcaacccc cagaaacagg agcaaggctt
    83161 aggtagccag gctttaagga aatttgttag tttggccttt gaaaatgaag atatatatag
    83221 tatttctcta aatgtcttcg aggcaaatca aagagctcag aatctttacc aaaaagaagg
    83281 atttgaaatc gttcaaatgg ttgaagcacc tgtacgaaaa tatagtatat tgaaactaga
    83341 atagtacacc tctacttcta aaacattgtt agaaatcgat ttgactgtcc cgatcgattc
    83401 gtcctgttat tatttcattt tactatacat tatgaaaaag gggagatagg agtataattc
    83461 caaatataaa gaaagcgaac aaaacagaat tctgattttc agaaaacagg tttgttcgct
    83521 ttttatgata tactccctct ttttagccta tttattaaat gtaatagaaa attaggaatg
    83581 tagaattgta tgatacaaac aaagtgcaat agctgagtgt gcggctgtaa aatcattgta
    83641 aggttcaata atgacttcag gtaggcgatt atagagcagt ttgggtttgt agttcatttc
    83701 actatatagt ttttggatga tgtgttgatt tgttagtaaa ggactatgta ggtagatttt
    83761 ttgagagtca atcatcatac tgatatttaa aatggtttga ctaagataga gtaaggcttg
    83821 atggataagt gtgattattc cagtgtcacc taattgataa gcggttaaaa taacttggat
    83881 atcaatatca tcggcatttt tgactaaact aggaagtaga gaatagggag attgatgata
    83941 tagaattttt gattttttga ttaaccaaga ttctccagca aaagtttgta agcatccctt
    84001 gcgcccgcaa ctacattctt ctccctcaga tgaaacaact gtatgcccta tttctccaat
    84061 cattagattt ccttttccat aaatgtttcc gtcgtagata taagaacagt gcatacctct
    84121 agcaaaatga aaataagcaa aattagggtc attctgttgg cgactaaata ggcgtttacc
    84181 tatagccata cagttaacat tgttagagaa aaacaaaggc ttatcaaagt gggattgaat
    84241 catttctaag tcgatatgtt gccataaagg attgtttgtt gttattttat aatcatctaa
    84301 atagcgacca ggtagcgcga ttccaattgc ttctatttca taatcagagc agttatttaa
    84361 gaattgcttt agtgtctggc taatgagttg atttcccttt tcttggatta actgtttagt
    84421 aacaatttct ttctcttcct ttaagatatt tcctagatta tctcctaaag caaaagtgaa
    84481 atgtttttca gatagttcac aaccaatgta gtaaaatcgt ttagcttgaa tgtctagcag
    84541 gatttttttt ctccctacgc ttgtatcgtg ttcgtcttca ccaagttcta agagaatgtt
    84601 ttctttaatc agatcatttg tgatactgct agttgttgca ggtgttattc ctgttttagt
    84661 agcgatttca attcgtgaaa tgggacctaa tgtgtaaact gtttccagta ttttagctcg
    84721 tagttgtaat tgtttcttag ataaggtcat attagttttc ttcctagttg tcagattctt
    84781 aaaatcctat gattttttgc tatggataaa tgtagatgtt aatcttttta agcttttcat
    84841 tgcttactgg tctcttttta ttatatattg ataataaaaa ataatcaaat atttacacaa
    84901 atccttgaca aggctttctt atagttgtaa aatataaata acaaaagata atcaaataac
    84961 aacttgacgt caaaaaataa agataattga taacttttga taataaaata tatttaagag
    85021 gaaaaggtta tggaaaaatt attacaagaa aagttacttc cagtagcggc tagattgggt
    85081 aataataaag cgttggtttc tattcgagac ggtattactc taactatacc tttattgttg
    85141 ataggttcat tactaatggt tattgcaagt tttcctattc caggatggga aaaatatctg
    85201 ggtgatattg gtgttgctga ctatttatgg aagggtgttg atagtagttt tggattactt
    85261 ggtcttgtag ctagttttgg tatcgcttac tttatggcta gacaatacaa agttgatggt
    85321 attcctgctg gtattgtgtc attatcatct tttattacag ttacgccttt cattagagga
    85381 gaggctggag caggaatgcc taccgctttc atggcatcaa aaggtttatt tgttgctatg
    85441 attttaggat tgattaatgg ctatatctac caatggttta taaatcataa tatacagata
    85501 aaaatgccgg atggtgttcc accagcagta tctaaaagct ttagtgccat tattcctggt
    85561 gcagtgacta ttgttggttg gttgattgtt tatgcaactt tagataaatt aagtttacct
    85621 aatcttcatg aaattgctca agtagctttg ggaggtccac ttggactttt aggaaataat
    85681 gttattggtc ttcttatctt aattttcctt aatagtagtt tttggtttgt aggattacac
    85741 ggaggaaatg ttgttaatgc agttatgaaa ccgttatggt tagctaatct agatgcaaat
    85801 aaagtagctt atcaaactgg agaaactctt ccaaatattt ttactagcgt atttatggat
    85861 aattttgtat tcataggtgg cggtggtgca accataggtt tagttcttgc gttaggatat
    85921 ttagcacata agaagaaagc tagtaaacaa ctaaaaactt tggcacctat aactgttata
    85981 cctggattat ttaatataaa tgaaccagca atgtttggcg tttctattgt tttgaacatt
    86041 ttgttactag ttccatttat cttagctcca atgtttaact tactagtagc gtggggagca
    86101 atggcatcag gtttggttcc gctaacttat acagatccag gttggactat gccacctgtt
    86161 ataagtggtt tacttgctac aggaagtatt tctggttcat tattacaaat tgtattgatt
    86221 gttttggatg tcttacttta tttaccattt gtaatagcta ttgaaaaacg gtttaagtta
    86281 ttggaggatt gagaatgaaa cgtttaatta gtgcaaatcc atctgagata ttacagatga
    86341 atgctgaaga attaaaacaa agtattttag caagtgaagg tagagttgtt ctatctgaaa
    86401 atgtagttac tcgtgagaca tttgttgggg atataactaa ttctgaaatt gctagagctt
    86461 ttggagctga tatgatttta ttgaattgtg ttgatgtttt tgagcctaaa atttatgctt
    86521 tggatagttc aggtgatgat gttattcatc gcttacacca gcttgttgct tgtccaattg
    86581 gtgtaaattt ggaaccgatt gacccatctg caaagatgct agaggaaaca caggaaattg
    86641 ttgcgggtcg tgttgctagt gttgaaacat tgaagcgaat agaggagtta ggttttgact
    86701 ttgtctgttt gactggaaat cctggaacag gagttagcaa tcgagaaatc attaagactg
    86761 ttcaaactgc taaggaaaac ttttctggtt tgattattgc aggtaagatg cacggggcag
    86821 gagtgaatga gcctgtggca gagctttctg tcgcagagca attgttggaa gcaggtgcgg
    86881 atgtgatact tgttccagca gttggaaccg ttccagcctt tcatgaccaa gagttgcgtg
    86941 aagtcgttga tctcgttcat agtaagggtg ggctagtact gagtgctatt ggtactagcc
    87001 aagaaacatc tgatacagat actatcaagg aaattgcact tagaaataaa atttgtggag
    87061 ttgatattca acatataggt gacgcaggat atgggggact ggcaacagtc gataatattt
    87121 atgcattgag caaggcaatt agaggagtga gacatacagt atctcgcttg gctaggtcag
    87181 taaataggtg ataaaggagt aagctatggc taaagtaaca attatgttag catgtgcagc
    87241 aggtatgagt acaagtctgc tagtgacaaa gatgcaaaag gcagcagaag ataaggggtt
    87301 ggatgcagaa atttttgcag ttccagctcc tgaagcagaa gaaattgtag caacaaaaga
    87361 agtaaatgtg ttgcttttag gtcctcaagt tcgctattta ctaggggact ttcaagaaaa
    87421 actaaaagat agacagattc ctgtggcggt tattccgatg acagattacg gaatgatgaa
    87481 tggttctaaa gttttagatt tagctgaaag tttattagac taagattgag gagaatgcta
    87541 tgaatgaaag taatttagaa tctgtaatgg ggctaattat gtatggtggg gaagccaaaa
    87601 gtaatgctat ggaggctatt caggcagcaa aaaaagggga tttctctaaa gccaatcgaa
    87661 gattagctga tgcgaatgct gccttattac aggcgcataa ggctcaaaca gaaatgttga
    87721 caagagaggc acagggggaa gaaacatcaa ttagcctctt gatggtacac gcgcaagatc
    87781 atttaatgac gagtctgact tttgttgact tggcgaaaga agtggtagaa gtatacgaac
    87841 gatttgaaaa aaattaggaa tttgctatga atacaatgtt ggataaaatg caagaaaaac
    87901 tttctccaat tgcaatgaaa gttgggaatc agaagttttt agttgcttta cgtgattcat
    87961 ttgtggggac tatgcctgtt attatgacag gttccattgc tttgttatta aatgcttttc
    88021 tagtggattt accacaacaa tttcacctag aaagtattac gaaaaccttt cagtggcttg
    88081 ttgacatcaa taatttggta ttcaagggaa gtataccaat tgtttccttg ttgttcatct
    88141 attgcttggg agtgaatatc gctaagattt ataaggttga tacagtttct gctggtttgg
    88201 tatcgcttgc ttcgtttgtc atttcgattg gaagtacagt tacaaagagt ttccctttgg
    88261 caaatgtagg agatgtgaaa ttagatcaaa tcttacaagg aattgataat ctagcatttg
    88321 atggtaaaaa tctgatggta actattggga atgtgattcc aggaaaccat attaatgcca
    88381 gaggctactt tacagccatg atgattggat ttttagcctc tattattttc tgtaaagtaa
    88441 tgaaaaagaa ctgggtaatc aagttaccag attcagttcc ccctgcgatt gctaagccgt
    88501 tcacttctat cattccagga tttatggcga tgtatatagt agctatcttg acttatgttt
    88561 tccatttact tagcaatgac ttattgattg attgggttta caaggtgtta caaacgccat
    88621 tactaggttt gtctcaaagt ttctttgcag ttattctgat gatctttttg aataagttat
    88681 tctggttttt tggtctccat ggaggaaatg tattggctcc catcatggaa gggctgtttg
    88741 gagttgctat gttagcgaat ctggatgctt tccaaaaagg tgaaccgatt ccttatatat
    88801 ggacaagtgg gtcttttggg gcgtttgtct ggtttggagg attaggatta gtacttgcta
    88861 ttttaatttt ttcaagaaac agtcattatc gaaaagttgc taaacttggt ctagcaccag
    88921 ttctgtttaa tattggtgag ccggtcaatt atggtttacc agttgtcttg aatcctttgc
    88981 tatttatacc atttgtactt agcccggttt tcatggcaac ggtagcttac tgggcaacaa
    89041 gctggggtct tgtttcatct gttacacaaa atgttacttg ggtaatgccg ccaattttat
    89101 atggtttctt ctctacagca tttgattggc gtgccatcat cttatcagtt gtttgtttga
    89161 ttattagtgt cttgacttat ttcccatttg tgaaaatggc agataaaact gaattgagtt
    89221 aatggtctta cttgtgtttt ttgtgataaa atagaaatag attacgtgta agatgagtta
    89281 ggtgtaggat ttcttatctc cactaaaatt gttattagac aaaggtttat aatttattga
    89341 agttggaata gtacactgta acttctaaaa cagtactaga aaatgatttg aatttcctaa
    89401 tcgatttagt catattttag ttcatttttc tataaaacat aacaagaatg ttattgtttt
    89461 atatagagag attgatatag aaaggggtgc agtaaaggta gatatcttct tgtgcctctt
    89521 ttgccatatt agaaaggaga ttttatggtt cagacaaaac agccaaatat tattttgatt
    89581 gttgtagatc aaatgagagc agacgcctta tccttgaata gtaaggataa gctagttagc
    89641 actccaacat tagatatgat ggctagtgta ggttataatt ttgaaaatgc ctattctcca
    89701 gttccttctt gcgttcctgc tagggcagct ttattgactg gcttagacca agataaaagt
    89761 ggacgagttg gttatcaaga tgaggtgcct tggaatttta ctaatactct tccaaaagtc
    89821 tttaaagata tgggttatca aacagagtgt attggtaaga tgcatgtttt tccttccaga
    89881 cagagacttg ggtttgatca tgtcttactt cacgatgggt atctacatgt tgatagaaag
    89941 tatgataagg cttatggaag tcaatttgat tatgctagtg actatctagc ctttttaaag
    90001 ggtaaagttg gttatgatgt tgatttgatt gatgacggaa tggattgtaa ttcttgggaa
    90061 gctagacctt gggataaaga tgagaagtta catccaacaa actgggttgt gagtgagtcc
    90121 atttcatttt tacaaagaag agatccaacg gttccttttt ttctcaaaat gtcttttgaa
    90181 aaaccacatg ctccattaaa tcccccaaaa tactattttg atatatatat ggaacgcttg
    90241 cctcaatttc tcgatttgca tatcgggaat tgggaagtat tagaaaagca aattccgtct
    90301 atttatgctt taagagggaa attaaaggaa gatgatcaaa gaagaatggt tgctgcttat
    90361 tttggattga ttactcatat agaccatcaa attagtcgct ttttgactgc cctaaaagaa
    90421 tttcgtcatg ataaagatac gattatctgg tttgtttcgg atcatggaga tcagcttggt
    90481 gaacattatc tgtttagaaa gggatatcct tatcagggaa gtatccacat tccttcgttt
    90541 atttacgatc cggctggatt gatagctggt aataggggaa caatcaagca attagtgaaa
    90601 attcaagata tttttccttc actcgtggat ttggcaggag gaactactac agatgaacta
    90661 gatggacgga gtgttaagaa tttattattt ggacagtacg aggggtggcg aacagaattt
    90721 catggtgaac atgctttagg aaaagattct agtcaatata ttttgacaga ccagtggaaa
    90781 tttatctggt ttcctgtttt aaatcattat cagttatttg atatgaaaaa agatccgcat
    90841 gaaatgaatg atttgtatcc aagtgaaaaa tatcaaccta ttgttcgtca gatgaagaaa
    90901 aaattagtag actttcttag atatagagaa gaaggttttg ttgtggatga agagttagtt
    90961 cctgttgaac tttctaaaat aacgccaact ctaacgaaaa cgggggatag tcaatcatga
    91021 aaatgaaaaa aatcaagggt gggacattta tgatgggaac aaattctgaa gagggctttt
    91081 tagatgattt tgaaggtcct caagtcgctg ttagtgtaaa ggatttttcc attgcggata
    91141 ctccagttac gaatcaagaa tttgctcaat ttgtgaaaga aacaggctat aaaacactag
    91201 ctgagcgaca agagtggtct tttgttttta tattgttcgt tccggaggca gaaagggagg
    91261 gatatcctca tcctgctggg gctccgtggt ggttacaagt ttcgaacgct tgctggaaac
    91321 atccctacgg tgagaacagt aatctagtgg gtttagaaga ccatccagta gttcatgttg
    91381 ctttagaaga tgcattggct ttctgtaatt ggagcggaat gtctttaccg actgaagcac
    91441 agtgggaata tgctgctaga ggaggaagac aatctgaata tccttgggga gatactcttt
    91501 tagaaggtgg atattatcat gccaatactt ggcaaggaag atttccttat gaaaatactg
    91561 ccttagatgg atttatagga acggctcctg tctatgaatt tttacctaat gattttggtc
    91621 tatatcaaat gattgggaat gtttgggaat ggtgtcgcaa tccgagatat accttattag
    91681 ctagttttaa tgaagatgac tatgagttac caaaatatgg gatacaagat gaagagtatg
    91741 ctatcagagg aggttccttt ttatgtcatt gttcttattg taatcgatac cgagtagctg
    91801 ctagaaatgg atgtatttct acttccacta gtagccatct aggttttaga tgtttgaaag
    91861 aataggatgg acttaaaaag tggttgagat tatttatttt ctaatcatta taatagctag
    91921 tggattgggt tctatatcag gcatgggtgg tggaattata attaagccac ttatggatag
    91981 ttttggatac cattcggtca gtgatattgc tttttattct agtttctctg tttttataat
    92041 ggcgattatt tcaacaatca aaagattttc acaaagtaaa gagataaaat ggagattgat
    92101 ttttacggta tccttttctt ctgttttagg agggtttcta ggtcatctta tttttcaagt
    92161 tttgttatct caattatcag tacggctagt atccattgtt caaatgattt tactatttgt
    92221 gatgctactt gtatcatttg ttttaacaga ttttaaaaaa acttatcaat ttgataagat
    92281 aggattctat atgatttgtg gtcttctatt gggcttgatt tctagttttt tagggattgg
    92341 tggtggtccg ctcaatgtat ctttattgat ggtgtttttt tctatttcga taaaagaagc
    92401 aacgatgtat tctcttgcaa ttattttctt ttcccagttg tctcatttgg ctacaattgt
    92461 tgtggttaca ggtttaaatc agtatcattt agcacctgtt ccagttattt ttcttgcttc
    92521 tatatgcgga ggggtattgg ggacggttgt atcaaaagtc ttacctgaaa attgggtaag
    92581 atactgtttt aaagggatgt tattctttgt catggaaatg actttatata atttatttca
    92641 tattttgtaa ggtcagtgtg aaaatattta aatagacttc ctgtaaaaac tggatttaac
    92701 gccctccatt tgtcaaatta agctagacag tcttaccaac tcagaaaata cctgataagg
    92761 atttaggtgg gatgtgattt cttgaggctg ggaaaaagtc tttaaaatta aaaaatgcat
    92821 aatatcaggt gttggaaaaa ctttgatact atgcgtttta ttgtgggaat atttatttca
    92881 ttttctcctg aaattgagtt tttgtccagc ctaaaattct tgactgactt cgttgaaatc
    92941 tgtctgcttt ggcaagtcat gacaccttaa aagtctattt gaatgttcgt tgagacaccg
    93001 ctgtcttgaa catcctagat tcgcaaaaaa gctctcacta tcgtgatgat tggaaatatc
    93061 tttccatttt gaaaactctt ttccacagtc aaacgtaata gatttaaaga ggttcactag
    93121 aaattgtgcc agccaccctt ggatggattc tgccatatcc tttgccttac gactcttggt
    93181 cttcaaactg acaatcaatt gactatacct gttcgctcac aaataggaga gaacttttta
    93241 cgaaaatcta atgaatatgc cacaagaaca ttataccgca acgtgtacta tttttggttc
    93301 attttattat agaaactatt gaagcaccgt acgaaaatat atcatgaaaa aggggagata
    93361 gaaagcaaac agccttgaaa tcaatgttga ctgcgattat gaacctgaat cagcccctca
    93421 aaagggactg tatatgaatg aacgttacca gtgtttaaaa actaaagaat atcaggcact
    93481 tttatcttcc aagggtagac aaattttcgc taaacgtaag attgatatga aatctgtctt
    93541 tgggcagata aaggtttgtt tgggttataa gagatgtcat ctgagaggta agcgtcaagt
    93601 gagaattgac atgggattcg tactcatggc caacaacctg ctgaaatata ataagagaaa
    93661 gaggcaaaat taaaaagcta gagttccgca attgggaatc tctagctttt tgttttctga
    93721 gaatcatctt gactcagact cttttgacta atgttactaa aaagataaag taacttttaa
    93781 ccttatttat cgtcgccact caacatgttt ttaacacctt ctacagcacc ttctacagcg
    93841 tctttagcgt cttcggcaac ttcttttact ttagaaacaa ctttttcagc tgctccttct
    93901 ttttccattt tttcatcacc gatggctttc ccaacacctt ctttaataga acctttagct
    93961 tgatttaatt tttcttctac tgacatgata atttctcctg ttatatttat tttatcttag
    94021 tttacacgag tgttttcgtg agatactaca ccatttgctg cacctttaac agcttctaca
    94081 ccttcgctaa ctttttcttg aacagttgag aaaccagatc caagaccaga tttagctttt
    94141 tcgaattgtt ctgaagtgaa ttctcctgtt gattcagcaa cgtcagatac gcgatcttga
    94201 aggcttactg agtctgcttc atgctgttct ttagttttga tgtcgacaac gtttacgttg
    94261 atttcaacaa tttccaagtc agtcatttta gcaacttctg aagatacgat ttctctgatt
    94321 tctgaatata aagctggaac atttttttgg tactcaacaa taacgtttaa gtcaactgca
    94381 acttgtgttt taccaacttc tacgttaaca ccacttgtta cgtcatcgct gttaacgatt
    94441 ttttctttaa gatttgagaa gaaaccacca tcgattccca aaagacctga aacgttttct
    94501 agtgaaagac caatgatttt ttggataact ttatcttcgt aagtaagttc ccctttgatt
    94561 tcgtgagcta caacagtagc atctttcttt tctacgttag tgtttgtgtt tttttcgttt
    94621 gacatatgaa actcctttaa ttaaattagt aatttttatt tttttattta tctatatagt
    94681 ttttttcgat atataatcca gctgcaactc ccagtgctcc taaaatcaat acaaatattg
    94741 ttttgaagaa gccaaaggag acaatcaaac aagccagaaa tacgcctatg agaccagcga
    94801 taattggata tcgatattgt ttaagccatt ccatttttta cttccttact tcacacgact
    94861 aacagtcttt ttgttttgag gttttggttg gtaatttttt actgcaactt caagttttac
    94921 ttgacgctca ataccaaaaa actgcttcaa tccattagtt atttcatttt gaattatttg
    94981 gcatctgtca gcgatgttgt ctgaaggaag aattttacct tctacatgaa cgaaacattt
    95041 attttttcgt aaatttacat gaacagttgg gttcttgatc aatctatgat cactcaccaa
    95101 acttctaaca aaaccttcga ttgccgaatt ctttaatttt aatgtatcgt ttttagtttc
    95161 aagttggatt tccaagtaac gtttaggata aaacatcaca actaaaatgg ataataaaac
    95221 taaagttgat agaaccactg tcccccaaaa gacatatcta gcaagataga attcaactac
    95281 ggagttctgt ctccagctaa gtagatgaat acctagatca ctaacttgat gataatctat
    95341 caaaacagga aggaaaattg tcaagattaa aatacagaaa ataatgaaac atattttctt
    95401 tgcttttgac atatacaatc ctttcgattt aacatttaaa ctatttttcc cgtcattgat
    95461 ttaaaaatag tttgctaact ttactggcga aaagtttact ttctacctgt aaagaatgac
    95521 actacagtaa tcacaatcgc tgcacctaca atagatggga gcaaagccat tccagcgatt
    95581 gatggacccc aactacctaa aagagattgt cctgcagatg ccccgactaa accagcgaat
    95641 acatttgcga tgattcccat agaactactt ttttagtgat tttacctgcc aagagaccaa
    95701 taagacctcc agcaataatt gatcacaaca ctgcctaccc tcctttttat tttaatatca
    95761 aaaaatcaat ttctttgatt attgctatta tataacttta atatagaaaa gtcaattatt
    95821 tcgattgtta ttattatata attttaaaaa atcaaattct ttaattgttg ctattatata
    95881 atttttaaaa ttaaaaatat aatctttaga cttgaatttg attctgtatt cacgccctca
    95941 atagacggta aaataagaaa attgtttata tattgtctcc gtagtgttat tatacgaaat
    96001 aaaagatttt aggaaaagtc gttatatcat gctataccta ttctttgtgg tataattgca
    96061 agaggtttaa tccgataatt tataaagaga gaaagatatt catgagagat ttattatcta
    96121 aaaaaagtca taggcaatta gaattattag aattattatt tgaacataaa cgttggtttc
    96181 atcgttctga actagcagag ttattaaatt gtacagaacg tgcagtcaaa gatgatctat
    96241 cccatgttaa atctgctttt cctgacttga tttttcattc ttctactaat ggtatacgca
    96301 ttattaatac cgatgatagt gatattgaaa tggtttacca tcatttcttt aaacattcaa
    96361 ctcatttttc gattttagaa ttcatcttct ttaatgaagg ttgtcaagct gagagtattt
    96421 gtaaagaatt ttatatcagt tcatcttcgc tctatcgtat tattagccaa atcaataaag
    96481 tgattaaaag gcaatttcaa tttgaagtca gtctgacccc tgttcaaatc attggaaatg
    96541 agagagacat tcgttacttt tttgcacaat atttttcaga aaaatattat ttcctagaat
    96601 ggccatttga aaatttttca tcagagccac tatctcaatt gttagaattg gtttataagg
    96661 aaacaagctt tccaatgaat ttgtcaacgc atagaatgct aaagttgctc ctagttacga
    96721 acctatatag aataaagttt ggtcatttta tggaagtaga taaagattct tttaacgacc
    96781 aaagtttgga ttttttaatg caggcagaag gaatagaagg tgttgctcag agttttgaat
    96841 cagaatacaa tatctcttta gatgaagaag ttgtttgcca attatttgtg tcttactttc
    96901 aaaaaatgtt tttcatagat gaaagtctct ttatgaaatg cgtaaaaaag gatagttatg
    96961 ttgaaaaatc ttaccatcta ttgagtgatt ttattgatca gatttcagtc aagtatcaga
    97021 ttgaaatgga gaataaggat aatctgattt ggcatctgca taataccgca catctgtatc
    97081 gtcaagagtt gtttactgag tttattttat ttgatcaaaa agggaataca atcaggaact
    97141 ttcaaaatat ttttccaaaa tttgtttcag atgtaaaaaa agagctttct cactatttag
    97201 agactcttga ggtttgttct agttcaatga tggtaaatca tctatcttat accttcatca
    97261 ctcataccaa acatttggta attaatttgc tacaaaatca gcctaaacta aaggttttag
    97321 ttatgagtaa ttttgatcag tatcatgcaa aattcgttgc agagacactt tcttattact
    97381 gtagcaataa ttttgaactg gaagtttgga ctgaattaga attatcaaag gaatctttag
    97441 aagattcatc ttatgatatc attatttcta attttattat tcctcctatt gaaaataaga
    97501 gactcatcta ttcaaataat ataaacacgg tctcactcat atatttgtta aatgccatga
    97561 tgtttattcg attagatgag taaccaaaaa taacaaaaaa acgctatttc gcgtttgaac
    97621 tgtacctcaa aagttagaca gaaaaatcta atttttgggg tgtttttgtt aagaaaagac
    97681 cttcaatcat ttaagcaaaa tgtacatcta gatttatagc cctctaaaac tcttgctttt
    97741 tttgtagaag atacgaaaaa agccatgaaa ccaaggcttt tcctgtttta tgtagatgtt
    97801 tacacatgaa aattgaagta ttttcaaaag ctaattggag tgattttatt catgatggga
    97861 taaatgatct ggccaaaaat gattgagaaa tagttgctta aaaagcattt gcatgatact
    97921 atatattgaa aggaggtgat aatatggtag aacaaagaaa atcaattacc atgaaagatg
    97981 ttgctttaga agcaggagtt agtgttggaa ctgtttcacg tgtaattaat aaagaaaaag
    98041 gcattaaaga agtaactttg aaaaaagtgg aacaagcgat taaaactttg aattacattc
    98101 cagattacta cgctagagga atgaaaaaaa atcgaacaga aacgattgca atcattgtac
    98161 caagtatctg gcatcccttc ttttcagaat ttgctatgca tgtggaaaat gaagtctata
    98221 agagaaataa caaattactc ttatgttcta tcaatggtac aaatagagag caagactatc
    98281 tggagatgtt gcgtcataat aaagttgatg gagtggttgc cattacctat agtccaattg
    98341 aacattactt gacgtcagga attccctttg ttagtattga ccgcacatac tcagatattg
    98401 ccattccttg tgtttcatca gataatgatg caggtggaag agaagcagct aaacaattaa
    98461 ttagtaaagg atgtcagcat ttagcctttg tgggcggaca taatacaacc attaatgaaa
    98521 ccaaacgttg tagaatttca tttgaaaagt atgtccaaga gcataaaata cctcttagta
    98581 tttttgattt ggatgagaca gttactgact attatggaaa gctagagagt ttcttggaag
    98641 aaaattcttc tatagatgga atttttacaa tcaacgattt tacagctttg gatgtgattg
    98701 aaatactaga aaaaaatggt aaacgtattc ctcatgatgt ccaaattatt ggatacgatg
    98761 gaattaaaat ggctggagat agagattatc tactttcaac tattgaacaa ccattggaag
    98821 aaatggcaaa agaagcggtt cgtattttgt ttgatataat tgatggaaag actgttaatt
    98881 tgcagacaat cctaccagta aaatttgttg aaggaaaaac aacaaaaaat gaaaataagt
    98941 cttgacagaa agcgctatca atgatagaat gaattcagat aaaaaagatt tatttttaaa
    99001 acaaaaatga aacgtttcaa aaaagaaata aagagacagc gccaagcgct atcttttcta
    99061 gaaaaaaatg aaacgtttca aaaaggaggt tgctatgaat agcaaagcga agcaagtttc
    99121 tctttgggaa agaatcaaga aacaaaaact cttgttattg atgactgtcc ccggtttagt
    99181 tttaaccttt atctttaaat acatccctat gtatggggtt ttaatcgcat ttaaagatta
    99241 caatccttta aaaggaattt tagggagtga ttggattggt ttttctgagt ttacaaaatt
    99301 catatcctct cccaactttg gtatcttgtt agccaacaca ttaaaattaa gtatctatgg
    99361 tttattgctt ggctttttac caccaatcat tcttgctatt atgctcaatc aactcttgag
    99421 tgaaaaagtc aaaaaacgaa ttcagctcat tttatacgca ccaaacttta tctcagttgt
    99481 tgttattgtc ggtatgattt tcctcttctt ttcagtggga ggaccaatca acaattttct
    99541 ttctatgttt ggaatgaagg ctgacttctt gacaaatcca gacttcttta gacctttata
    99601 catctttagt ggtatctggc aaggaatggg ctgggcttca acgctctaca cggcaacatt
    99661 ggtaaatgta gatccagcct tagtagaagc agcccgactg gatggagcca atatcttcca
    99721 acgaatctgg cacattgata ttccagctct taagcctatt atggttatcc aatttgtttt
    99781 agctgcaggt ggaattatga atgtcggata tgaaaaagca ttcttgatgc agacatcgtt
    99841 aaatttgcca acttctgaaa ttatctcgac atatgtctat aaagttggtc ttgtatcagg
    99901 agactattct tactcaacag cggttggttt gtttaatgca gtgattaacg tagtattgct
    99961 tgttgcagtt aaccaaatcg ttaaacgcat gaataatggt gaaggaattt aaggaggaaa
   100021 gtatgaaaaa ttcgattatg gatacaaaat ttgatagacg tatcttactc ttaaataaaa
   100081 tcattattgt ctttatcgtt ttgatgactt tgcttccttt actttatatc gtcgtagcat
   100141 cctttatgga tcctaaggtt ctggttagta gagggattag ctttaatcca gccgattgga
   100201 ctgtagaagg ttaccagcgt gtattcagtg accaatctat tctaagaggt tttatcaatt
   100261 ctctactata ctcttttgga tttgcagctt taacagtatt gctatctgtg tttacagctt
   100321 atcctctttc taagaaagac ttggttggac gtcgttggat taactacttt ttgattgtga
   100381 ctatgttctt tggtggtggt ttagtcccaa cttacttgct cgtaaaagaa ttgggaatgc
   100441 tcaatactcc atgggctatc attgttccag gtgctgtcaa cgtttggaat attattcttg
   100501 ctagggccta tttccaagga ttgcctgaag aattagttga agctgctgtc attgatggtg
   100561 caaatgattt acagattttc ttcaaaatca tgcttcctct tgcaaaacca attatgtttg
   100621 ttctcttcct ttatgctttt gtaggacagt ggaactcata ctttgatgca atgatttata
   100681 tcaaggatcc aaacttggaa ccattgcaac ttgtacttcg taaaattctc attcagagcc
   100741 aaccaggtca agacatgatt ggagcacaag cggctatgaa tgaaatgaaa cgtttagctg
   100801 aattgattaa atacgcaact attgtcattt ccagcttgcc attgattgtt atgtatccat
   100861 tcttccaaaa atactttgat aaaggaatta tggctggttc acttaaagga taaaaaaaga
   100921 aaaaataaaa ggagttttct catgaaattc aaaacattct caaaatcagc agttttgttg
   100981 acagctagtt tagcagtact tgcagcctgt ggctcaaaaa atacagcttc aagtccagat
   101041 tataagttgg aaggtgtaac attcccgctt caagaaaaga aaacattgaa gtttatgaca
   101101 gccagttcac cgttatctcc taaagaccca aatgaaaagt taattttgca acgtttggag
   101161 aaggaaactg gcgttcatat tgactggacc aactaccaat ccgactttgc agaaaaacgt
   101221 aacttggata tttctagtgg tgatttacca gatgctatcc acaacgacgg agcttcagat
   101281 gtggacttga tgaactgggc taaaaaaggt gttattattc cagttgaaga tttgattgat
   101341 aaatacatgc caaatcttaa gaaaattttg aatgagaaac cagagtacaa ggccttgatg
   101401 acagcacctg atgggcacat ttactcattc ccatggattg aagagcttgg agatggtaaa
   101461 gagtctattc acagcgtcaa cgatatggct tggattaaca aagattggct taagaaactt
   101521 ggtcttgaaa tgccaaaaac tactgatgat ttgattaaag tcctagaagc tttcaaaaac
   101581 ggggatccaa atggaaatgg agaggctgat gaaattccat tttcatttat tagtggtaac
   101641 ggaaacgaag attttaaatt cctatttgct gcatttggta taggggataa cgatgatcat
   101701 ttagtagtag gaaatgatgg caaagttgat ttcacagcag ataacgataa ctataaagaa
   101761 ggtgtcaaat ttatccgtca attgcaagaa aaaggcttga ttgataaaga agctttcgaa
   101821 catgattgga atagttacat tgctaaaggt catgatcaga aatttggtgt ttactttaca
   101881 tgggataaga ataatgttac tggaagtaac gaaagttatg atgttttacc agtacttgct
   101941 ggaccaagtg gtcaaaaaca cgtagctcgt acaaacggta tgggatttgc acgtgacaag
   102001 atggttatta ccagtgtaaa caaaaaccta gaattgacag ctaaatggat tgatgcacaa
   102061 tacgctccac tccaatctgt gcaaaataac tggggaactt acggagatga caaacaacaa
   102121 aacatctttg aattggatca agcgtcaaat agtctaaaac acttaccact aaacggaact
   102181 gcaccagcag aacttcgtca aaagactgaa gtaggaggac cactagctat cctagattca
   102241 tactatggta aagtaacaac catgcctgat gatgccaaat ggcgtttgga tcttatcaaa
   102301 gaatattatg ttccttacat gagcaatgac aataactatc caagagtctt tatgacacag
   102361 gaagatttgg acaagattgc ccatatcgaa gcagatatga atgactatat ctaccgtaaa
   102421 cgtgctgaat ggattgtaaa tggcaatatt gatactgagt gggatgatta caagaaagaa
   102481 cttgaaaaat acggactttc tgattacctc gctattaaac aaaaatacta cgaccaatac
   102541 caagcaaaca aaaactagag gttgattatg ggagataaga aatacacagt agaaaaagcc
   102601 aatcgtttta tagcagaaaa taaacatctc gttaatactc aatataagcc tgaagaacat
   102661 ttttcagctg agattggttg gatcaatgat ccaaatggat ttgtttattt tcgtggagaa
   102721 taccatctct tttatcaatt ctatccatat gatagtgttt ggggacctat gcactgggga
   102781 catgctaaaa gtaaggactt ggtgacttgg gagcacttgc cagtggcact tgctcctgat
   102841 caagattatg accgaaatgg ttgtttctca ggctctgcca ttgtcaagga tgatcgcctc
   102901 tggctcatgt acactgggca tatcgaagaa aaaaccggtg tccgccaagt gcaaaatatg
   102961 gcattttcag acgacgggat tcactttgaa aagattgaac aaaatccagt tgcaacagga
   103021 gcagacttgc cagatgagtt gattgctgct gatttccgtg atccaaaact ctttgaaaaa
   103081 gatggacgct attactccgt agtagctgcc aaacacaagg ataatgtggg ctgtatcgtt
   103141 ctactagggt ccgataacct agtagaatgg cagttcgaat ccatcttttt aaaaggggta
   103201 gaacaccaag ggtttatgtg ggaatgccca gattacttcg agttagatgg gaaagattgc
   103261 cttattatgt cacccatgcg ttatcagcgt gagggagact catatcataa catcaactca
   103321 tcgcttttgt tcacgggtaa ggtagattgg agagaaaaac gttttatccc agaatcagtt
   103381 caagaaattg atcatggcca agacttctat gcgcctcaaa cattgttgga cgatcaaaat
   103441 cgtcgtatcc tgattgcttg gatgcagaca tgggggcgta cccttccaac ccatgaccaa
   103501 gaacacaaat gggcatgtgc catgacttta cctagaattc taagattgga agatggcaaa
   103561 ctgagacaat tccctgttaa aaaaggccaa tatcaaatcc aaatagataa agattgtcat
   103621 taccacttag gaaatgatat agattatctt gaatttggtt atgacagtaa tgcgcagcaa
   103681 gtttacattg atcgtagcca tcttattcaa aaaattctag gtgaagaaga acaggacact
   103741 agtcgacggt atgtagatat tgaagctaaa gaattggaag ttgttctaga taaaaattcc
   103801 atcgagattt ttgtcaatca aggtgaagca agcttgactg caacttatta cttaacggtg
   103861 ccagctgagc tatcacgaat tgattaaaaa ttaagttatt tctcctaaag aaaaagttct
   103921 ctttctaaaa tagtggaaag aggacttttt gtgttttggg tatataagct tagtttatgg
   103981 tatttgtaaa attggtgttg gattatgatt taagctagtt ttctaaagaa tttgaaaaaa
   104041 attttattta agcaaaaaaa ccttggttcc aaggcttttc ctgttgtatt tagatgcccc
   104101 ctacagggat cgaacctgtg acccacggat taagagtccg ctgctctgcc agctgagcta
   104161 aggaggcaaa gaaaaaagct gtattggtgc cgaaacttca cggtttgtat tgaacccgcg
   104221 caattaagca ggtgggcaac tcgctctaac tgaagctgtt tccgtgtgag acggcctaca
   104281 tgctgttaga agacttttgt ttccctaata atacaaaaaa tagtcggtca acacttaagt
   104341 gtgaagtcgt acaccacagc gtttctatat ttatatgata ccactttttc aaaaaaaatc
   104401 aagaggaaag tgcaattttt tgaaaaggat ttcagatttt tcgcaaatgg tcgatagctt
   104461 cctttctttg agccaaagcc cgttcatatt taccagtatc ttctgcttgg aaatagtgat
   104521 gattacgaat tttttctggc agatagtctt gcttgaccca atttccagga tagttgtgtg
   104581 gatagagata gtcttgggca ttccccagtt ccttgcttcc actgtagtgc ccatcacgca
   104641 ggtgtcgcgg aataggcaag tgccctgatg ttttgaggtc agcaagtgcc ttatccatag
   104701 ctacataggc tgagttggat tttggagaaa gggccaaatc aatcacgaca ttggcaatga
   104761 gaatgcgggc ttctggaaac ccaatcttct gggcagcatc cagagcagtc acggtatgaa
   104821 tctgggcctc aggattggct aagccgatat cttcataggc gataacagtc aagcgacgag
   104881 cgagactagg cagatcccca gcctcaatca agcgggcagc atagtggaga ctggcatcca
   104941 catctgagcc acggatagac ttttgcaggg cagatagaac atcatagtga ccgtctccat
   105001 ccttgtccat agtgatgtag cttctctgaa gactattttc catgatgtct aaggtgatgt
   105061 ggcgaatgcc ctcgtcattc tcaggggtag agagaacagc caagtccagt gagttaaagg
   105121 cagagcgaag gtctccgttt gtagaggttg cgatgaaatc cagcgcatcc tcatctagtt
   105181 ctattggaaa atcaaaacca cgttcagggt tacttagagt tatctgcagg gcctctttga
   105241 cgtcttggtt agacagaggt tccaactcga aaatttgaac tcggctacga atggcaggag
   105301 tgacagagaa gaaaggattt tcagtcgttg ctccaatcat gatgaccagt ccactttcca
   105361 agagaggcaa gaggaagtct tgcttggtct tatctagtcg atgaatttcg tctagcaata
   105421 ggacgagacc accagaaaat ttagcttctt ccgagatttc ttgcagtcgc tttttactat
   105481 caactgtcgc attgaaagtt cgaaaggcat acttggtcgt tccagcgatg gcagaggcaa
   105541 tactggtttt gccgattccc ggagggccat atagaatcat ggaggacagg cggttggctt
   105601 ccaccatgcg gcggatgatt tttccaggtc cgaccagatg ctcctgaccg atgacctggt
   105661 cgatggtttt agggcgcatg cgaagcgcga gattgtctgg catagcagtc ctttctagcg
   105721 tggatttgag tagaatgact catctactat atcttactat gtccattcta gcctattagt
   105781 tgtgatattt caatggtttt gtaataatca gggagtgaga tagaatcttt tttactattt
   105841 aatttaatga ggagaggtat cagcatgaga gatttgattt tccttaaagc tcaaaatagg
   105901 atagttgagc ctaaagaagt ggaagtgctg acttgagaaa taatattgct gaatgtcatt
   105961 gtatgaacta taatgaaaag agaggtgata agcaatggaa atgatggacc aagtcaggaa
   106021 attttgattt ttacaaaaca aattcgtcat tggattctta gtgatcaagt tatttcaggg
   106081 aaaagaaaac ttttcttccg ggaagatact ccaaaagaga ttttagattt gtacgaaaac
   106141 attaaatcta aacttgattt tgcttaccaa gaagttcatt ctaataatgg gttgaaaaaa
   106201 tatgaaaaat agaataattg atgtttttga agtagtaaat cgcctccttg taataactgt
   106261 tgaaaatcct gatttcgaag acttgagagt taatcatact caatgaaaat caaagagcaa
   106321 actaggaaac tagccgcagg ctgtacttga gtacggtaag gcgacgttga cgtggtttga
   106381 atttgatttt cgaagagtat cagtttgtaa aaattggaga taaaaaatat agagtacgca
   106441 gtgttcctat gattcattca actccgcctc aatctgtctt agatcgagat acttttacaa
   106501 ttgactatac agatgatgaa ttgctcgata aagaagcagt ttttactact cattagaaaa
   106561 ataggtctga ataaattggc ttcccttaga accacatcta ggggctttta tgtataatag
   106621 aataataagt atcactcctt tacaatacgt gtaacacgtg ttataatggt gttgtcagga
   106681 ggtaaaagcg ctatgcctat gacacaaaaa gagatggtta aactccttac ggcccatggt
   106741 tggataaaga ctagaggcgg taaaggctcc catattaaaa tggagaagca aggggaaaga
   106801 cttatcacaa tccctcatgg tgagctgaat aagtacactg aaagagggat aagaaagcaa
   106861 gttgggttgt aaaattcagc ccctgttttt tgatatggag gtagtgaaat gttagttacg
   106921 tatccagctt tattttatta tgacgacaca gacggaacag aagcgactta ttttgtccat
   106981 ttcccagatt ttgaatactc agctacacaa ggagagggga tttctgatgc tttggctatg
   107041 gggtcggagt ggctagggat aactgttgca gatttgatag agagtgatgg agagttacct
   107101 cagccatcag atatcaatag cttgtcttta attgataatg atccttttaa agatgatgaa
   107161 gatttcgtgt caacctatga ccttgataaa tcttttattt ctatggtatc tgttgatgta
   107221 tcagaatacc taggaagtca ggaacccata aaaaagactt tgaccatacc aaaatgggca
   107281 gataagttgg gacgagaaat gggacttaac ttttctcaga ctttgacaga cgctattgca
   107341 gataagaaag ttcaagccta agattaagcg tagtatcgtg gtaatagtca ataaaaaagc
   107401 acgtccactt gtgctagtta ctcgcctatt gattttatag atttattagc cctttcgcgg
   107461 gctttttata ttgattttta tgagaaatga agaaatcaga cttttaagaa aatcactgat
   107521 accaagggtt taaatgaggt aatatggtat aattaggaca taaaataatt ttgtggtaag
   107581 atggtagtat ctattttagc atatttccga gcaatcgggg cgattaaaga gtcgcataga
   107641 aagaggacaa aatggcaaca tacggatttt tagatgtttt agaggaagag ttggacaaga
   107701 actttccctt tgactttgag attagctggg acaaacgcaa ccatgcggta gaagtgagtt
   107761 ttctattgga agcgcaaaat gctgcaggtg tggagatggt ggatgaagac ggagaggttt
   107821 tatcagatga cattcttttt gaggaagcgg tccttttcta caatcctgcc aagtcaacag
   107881 tcaatgagga agactatttg actgttattc cttacctgcc taaaaaagga ttttcccgtg
   107941 aatttttagt ttattttgcg cttttcctta aagatactgc tgaggttggg ctagatgtcc
   108001 tcatggactt tttggaagac ccagaagcag aggaatttgt catggaatgg aaccaagaag
   108061 tctttgaaga aggaaaagtt ggcttggaag agggagaatt ttacccttat ccgaggtatt
   108121 agaaaagatt ctaagtggac atttttaaat aatgaattca aggagaaggg ggagattatg
   108181 ctagaaaaag tcaaacagtt tttcaggagc aggtcagcta aaactgagcc gtcagttgat
   108241 attcttcccc gcaatcgctt tgcggatcta gatttcgaga gagtattgaa gtcaggagct
   108301 cgtcgccttg ttaatgagga aggacgctat gctgaggatg ggaaaatcac agaacttgaa
   108361 tttcctgaag attttgcgga atttgaattt ctagttggtt ttaagacgga ggaagaagag
   108421 cagtttcagc aactattagc tcgtttaaat agtattgaca atgctattca gtcctatttg
   108481 gaaagtgaga tgcaacaacc catccctcag tatgccaagg atctcggcta tactcagaag
   108541 aggtgggaga aaacctttta cttccatcct tggatattaa gtggtgagga aaacccgcct
   108601 aatcttcgct atgttgcaga ttatgtaaat gatgagttta cggtttattt tgctaaaaaa
   108661 catggcagat ggcaagcata ctgggatgca gagtgccaaa aagtaatcga agaaagctag
   108721 ctcgtatttt cctagagagt aattgttatc atagaaaaga gtaaatatca tggaattatt
   108781 gaatagcaga atggatttcc aaggttgcaa gattgccctc ttttgtgggg ataagctact
   108841 gacgattttg cgtgatgaca aggacgatat cccttgtccc aacatgtggg agttgccagg
   108901 tggtggccgt gaaggggacg aaagcccttt tgaatgcgct cggcgtgaag tttatgagga
   108961 actgggaatt catttagatg aagactgtct gctttggagc aagatttatc ctagcgtaat
   109021 ttttaaaggc aagaaatcgg tctttatggt tggtcagcta agacaagaac aatttgacaa
   109081 tatcatcttc ggagatgaag gacagggcta taaattgatg cctattgagg aatttctcaa
   109141 ttctaaacag gcagtgcctc agttgcaggg aagattgaga gattatttgg aggaaagttt
   109201 atgataacac ttgttcgagc gggagcagag gatttagaaa ctattattgc aattcagaga
   109261 gccagcttta aggctgttta tgaaaaatac catgatgaat atgaccctta tctcgaggac
   109321 tgcgaacgaa ttaagtggaa attagtcgag cgtcccaata gctattacta ctttgtaaaa
   109381 gaagatgaag aaaacattgg atttttacga gttcagacca atgccgagtt aacgaaagct
   109441 tggttgggaa cggcagcgat tttgcctcag tatcaaggaa aagggtatgg atctaaaggt
   109501 ttaagcttac tggaaaaaga atttccaacc atcacacaat gggatttgtg tacggtgtta
   109561 caggatgcag gcatggttgc tttttacgag aaaaacggct atcgtaaaat ccacattgag
   109621 gctgaaaaag aaggcatgga tatggtctac atgaaaaaat tgatagagaa atagaaagga
   109681 tggttcggtt aaatttctaa actgaacccg ccctaaacac ggtgccaaaa agataaactt
   109741 ctcttagaca caaacgtctt cagagagttt cctattttgg ctttgtgttt tacgggcttg
   109801 gtatcttaat aatggaaaca tggcaagagt taaaagttac agtgaagcgt gagggagagg
   109861 agttggtttc caatctcttg attgagttag gtgcccaagg ggtagcaatt gaagacagca
   109921 tggactatgt gggaaatgtg gaccgattcg gtgaaatttt cccagaggtg gagcaacagg
   109981 aagaaatcgt agtgaccgcc tactaccctg aaacggttga tgtagcagca gttgaagcgg
   110041 atttgcaggc tcgtctggca gaattgaccg actttatgga cctaggagaa gtcaagatgg
   110101 gcacgactgc cttggctgag gaagactggg cagataactg gaagaaatac tatgagccag
   110161 ctcgtatcac tcatgatttg accattgttc cctcttggac agactatgag gcgactgcgg
   110221 gggaaatgat tatcaagctg gatcctggca tggcttttgg tactggaacc cacccaacta
   110281 ccaagatgag cctttttgcc ttggaacagg ttcttcgtgg tggcgaaacg gtgctagatg
   110341 tggggactgg ttcaggggtt ctctctattg ccagctcgct tctgggggct aaagaaattt
   110401 tcgcctatga cctggatgat gtggcggttc gtgtggctca ggaaaatatt gagctcaacc
   110461 ctggcatgga aaatatccat gtagcggctg gagatttgct taagggtgtg gaaattgagg
   110521 cagatgtgat tgtggctaat atcttggcgg atatcctcat tcatctaata gacgatgcct
   110581 atcgtttggt caaggacgaa ggctacctga tcatgagtgg cattatcaag gataagtggg
   110641 acatggtgcg cgagtcggct gaatcagctg gatttttcct tgaaactcac atggttcaag
   110701 gggaatggaa tacctgtgtc tttaagaaaa ccaaggatat ctctggtgtg attggaggct
   110761 agcatgcagc agtattttgt aaaaggcagt gctatctctc ctgtcactat cgaggacaag
   110821 gaaaccagta agcatatgtt tcaggttatg cgcttgaaag aagaggatga ggttacctta
   110881 gtctttgatg atggcatcaa gcgcttggcg cgcgtgctgg atatggaaaa tcgtcagttt
   110941 gagttggtcc aagaattaaa tgacaatgtg gaactaccag tccaagtgac catcgcatct
   111001 ggatttccca agggagacaa gctggagttc atcgctcaaa aagtaaccga actgggtgct
   111061 agccaaatct gggcctttcc tgcagactgg tcagttgcca agtgggatgg caagaaattg
   111121 ggtaaaaaag ttgaaaaact agaaaaaatt gcccttggag cagccgagca aagcaagcgt
   111181 aatattgtac caagtattaa acttttcgag aaaaaagcag attttctagc tcagctggac
   111241 cagtttgact ctatcatagt agcctatgaa gaattagcta aagaaggaga agccgctgcg
   111301 cttctgcaag cagtcactga tcttgaaaca ggagccaaac tgctctttat ctttggtcca
   111361 gaaggcggtc tctcacctgt agaaattgaa agttttgaag ctaagggagc cgttttggta
   111421 ggcctaggtc ctcgtatttt gcgagcagaa acagcaccgc tttacgcctt atcagccctt
   111481 agtgttttag tagaattaga gaaataagag gaagaaaatg gaacaaaaac accgttcaga
   111541 atttccagag aaggaactct gggacttaac agccctatat caagaccgtg aggatttctt
   111601 gcgtgcaatc gagaaagctc gcgaagacat caaccagttt agccgtgatt acaagggcaa
   111661 tcttcacact tttgaggatt tcgagaaggc ctttgcggaa ttggaacaga tctacattca
   111721 gatgagccat attggcaact atgcttttat gcctcagacg acggactata gcaatgacga
   111781 atttgccaat attgcccaag ctgggatgga atttgaaaca gatgccagcg tagccttgac
   111841 cttctttgac gatgccttgg tggtagcaga cgaggaagtc ttggaccgtt tgggtgaatt
   111901 gcctcacttg acggcagcta ttcgtcaggc caaaatcaaa aaagcccact atctaggggc
   111961 tgatgtggag aaggccttga ccaatctcgg tgaagttttc tatagtccgc aggacattta
   112021 tactaagatg cgagctgggg attttgaaat ggctgacttt gaagcccatg gcaagaccta
   112081 taaaaacagc tttgtcacct atgagaattt ctaccaaaat cacgaggatg ctgaggttcg
   112141 tgagaaatcc ttccgttcct tctcagaggg acttcgtaag caccaaaata cggctgcagc
   112201 agcctatctg gctcaggtca agtctgaaaa actcttggct gatatgaagg gatacgactc
   112261 tgtctttgat tatcttctag ctgaacaaga agtggaccgt gtcatgtttg accgccagat
   112321 tgacctcatc atgaaggact ttgcaccagt cgctcagaga tacctcaagc atgttgccaa
   112381 ggtaaatggt cttgaaaaga tgacctttgc agactggaaa ttggacttgg acagcgccct
   112441 caatcctgaa gtgactattg acgatgccta tgatttggtc atgaagtcgg tagaaccttt
   112501 ggggcaagaa tattgtcagg aagttgctcg ttaccaagaa gagcgctggg tggactttgc
   112561 tgctaacagt ggcaaggatt ccggtggtta tgcggcggac ccatatcgcg tacaccctta
   112621 tgtcctcatg agctggacag gccgtttgag cgatgtctat accttgattc atgaaatcgg
   112681 gcattctggt caattcatct tttcagacaa tcatcaaagt tacttcaatg cccatatgtc
   112741 gacctactat gttgaagcac cgtcaacctt caatgaattg ctactcagtg attacttaga
   112801 gaaccaatct aatgacccac gtcaaaaacg cttcgctctg gctcatcgct tgacagacac
   112861 ctacttccat aactttatca cccacctctt ggaagcagcc ttccagcgta aggtgtatac
   112921 attgattgaa gaaggagaaa ccttcggagc aagcaaactc aacagcatta tgaaggaagt
   112981 tttgacagat ttttggggcg atgccattga aatcgacgac gatgcagctt tgacttggat
   113041 gcgccaagct cactactata tgggcttgta tagttacact tactctgctg gtcttgtcat
   113101 ctcgacagct ggttaccttc atcttaaaaa ctcagaaact ggagctgaag actggctcaa
   113161 tctcctcaaa tcaggtggta gcaagacacc acttgagtca gccatgatta tcggtgcgga
   113221 tatttcaaca gacaaaccac tccgtgatac tatccaattc ttgtctgaca cagttgacca
   113281 gattatctcc tatagtgctg agttgggaga gtaaggggat agagaggttg ttatagaatg
   113341 ggtatggata gttatttgct taaaagtcca tgtttaaatc ccccattcct tttcgaggaa
   113401 ttctttgccc ttctctgtaa tggtaagtga acgtggcgtt tgtgcaggga tgaccaattg
   113461 tttttcactg aaaaattcta aaagagcatt gccgagagct ccgccgacat gatttttacg
   113521 ttcgctccaa tccaaacatt tagggcaaaa tttccgtttt ttctttttca attcatccgt
   113581 atcaatgtgt aattttcttt ggaaataaga cttcccagct tcagtgagtt ggaagtcttt
   113641 ttctgattcg ctgaggagat tttcttgcaa gagataattg gtaatggaaa tgccaagctc
   113701 accagcaata tggtcatagc aggtgcgagc gacctttaat tcctttttgt gaatgtgttg
   113761 tttataactt ttgacatcac gctgaggaga gtagaagctg agaaattcca gcatttctgc
   113821 aatggcagca ctttttaaag aataataatg aaaacgtcca taggtttgta gagtggttac
   113881 ctgcgcttcg gtaagtaatt tgaggtgata gctgacagta tgttgcttga ttttggtaaa
   113941 gctggcaatt tcgttaaccg tgtgagcttt tccatccatt agaatatcta aaatgtgcat
   114001 ccgagaaggg tctgataaga gttttgtgat gatgaaaata tctggttcca taaaaatttt
   114061 ctccaaattt catatatcga tgattttcta tcttttatta tactataatt aaagcacaag
   114121 aaaaatagat tttaaaaatg ttttactaga gaatatttta aattttattg tctgagttta
   114181 aatagaggta aaattacaaa agtaattgca gcagtatcca cagttgaagg acgttaatct
   114241 taagattaca ttctcaacat tttttcaaaa gtgagatgaa ttaacaaagt atccaacatg
   114301 ctctatttgt gggggaaaga aagagtgaag aagttaagtg ttaaaaatct aaaaaagcaa
   114361 tatggttctt atgaagctgt caagggaatt agctttgaat tgggagaagg agagtgtttg
   114421 ggtatcttgg gaatcaacgg tgctggcaaa acatccactt taaagatgat ttactcactg
   114481 acctcaattt cctcaggaga gattgatatc ttggggcaaa atattgaaac caatcgtcgt
   114541 aagagtaaat cttgtctggg tattgtaggg caggaggata tgctggacat gaccttgaat
   114601 gtttatgata atctttttgc tcacggtcta tgctatggta tctcatctgt cgaacttagg
   114661 aagagaatcg attctctctt ggattttgtt caactgagca aacatgcgca aaagatggtg
   114721 aatcagctgt cgggtgggat gcgacgacgt cttgtcttgg caagagctct catcaatcgg
   114781 cctgatatta tcattttaga tgaaccgaca gttggtttag acattcaatc ccgcaatatt
   114841 atttgggata aacttttgga gttgaaggaa ttaggtgttt ccatcattat tacttcccac
   114901 tatatgaatg agattgaata tttgacagat agggtgctga tgctccacca agggactatc
   114961 aaagaagaag gaactgtaga agacttgctc atcaagtatg atgctgacaa ccttgagacg
   115021 ctttttttgg ggttgactgg gacagagaag gaggacttgc atgtttaagt tatcatttca
   115081 ctccatcgga cacgttgtgg tacgcaacta catgagtttt agaaatttat ttaaaatttc
   115141 aattgtcccc aatcttatcg accccctctt ttatctttta gcaatgggat ttggagttgg
   115201 tgcttatttg acgcatgtta acggtatgct ctaccgtgat tttgtcatta caggtttaat
   115261 tgctgcgact gccatgtctg cggccaccgc agaaacaacg gtcaatgcct ttatccagta
   115321 taagattgaa aagacttatg atgctatgtt gatgacgcca atcaatacga atgatattgt
   115381 ggtgggtcag gctatctggg caggtattcg tgcagtgatt tttggtggga ttttttggct
   115441 gatttccata cttatcacag cgcattttca tgtcttgatg ttattgattc ctctgatttt
   115501 atttatagtg ggttatttgt ttggtgtttt aggactaatc tttacctact tggcgccgtc
   115561 tagggaattt ctgaattact acaatgtttt ggcaatccgt cctctttata tgttttcaga
   115621 taccttcttt cccattactt ccttgccccc aatacttggt gatttgactt ggttttctcc
   115681 cttgtatcac gctacccgca tgattcgtat tatatgggga ggtgaggtga caggtttgta
   115741 tcttcatctt atctggttga tagccttggc gctcttgata acggtgcttc ctatgtatat
   115801 gttacatcgt agatattata gatagtctaa ttatttgtga ttttatacta aacgttattc
   115861 gaatttggac aggtatggga actgtgccta tcaatattgt aatttatgga agttgaaata
   115921 gtacggttca gtttttaaaa tattgttaga aattgtttta aattccctaa tcaatttgta
   115981 tagtttttat ttcactttat tataactagt ttttcgcaat ttttgagaca ggaatgtgat
   116041 ttttgtgata aggctctatc attacaagtt tatttgttgt aatatggaat aaatcattta
   116101 tatatctttt cagaaatatg ctgtttctct gaatataaat gtctttttct ttttaactta
   116161 attttacaaa ttggtaaggt catttaagac tgcctttttg aacagttgct agaaatgtag
   116221 aggtattgac catgtatcaa gatttactaa gaaaaatagc agaagaaaaa ccaaattata
   116281 accaggagga aatccagtgg ttgcttgatc atttgggaga tccttctcca gaaattcgtg
   116341 atgatcttgt ttttacaagc tttgctaagg agattcagga agagctattt acacaggaac
   116401 aatttcattt cattgctgag gtggtcttag ctgatggagg gttagataaa gagattgata
   116461 aggtaggctt gtcaacactt gaacgttctt ttagggcact tatttatgca aatctcttgt
   116521 ctgcagatgc taaccagcaa tcggtttttt atcagggatt acaatcagaa attcgtaatg
   116581 tccttttaaa tcaaggcttg cactatcttt caaaagaaaa ggatacaaca ggtttctcaa
   116641 gtcagtatgg ttgggttcat tcttttgcac atggagccga tttactgaaa gaggtggttt
   116701 gtcatccaga ctttcctaaa aacagagttc atgaagtatt tgatatactt ggccaactat
   116761 ttaaaagaat gtcgattcgc tttacagatg atgaggattg gcgtttagca agagtgatct
   116821 atgaacctat tttacaaggg aagttggagc aagaacaagt agcttcttgg ataaaaactg
   116881 ttgattttcc gatagaagaa agggaggatt tttacaaatt ttccaacttt agatcctgtc
   116941 tggtggaagt ctatgtccaa cttgaccaga gaaatagttt acaagatgag ttgaaagaag
   117001 ctatccagtc ttttcaatac tagagattag ctaatagttc tatgattttc aaaaaatttc
   117061 caatcaattt tcttgaaacc ctttcctact tttgatagac tagtatctag tttttgaaaa
   117121 aaggagaaag aaaatgaaaa aatttgttgc tgagttaatc ggtacgttca tgcttgtgtt
   117181 cgttgggaca ggagctgttg tttttggaaa tggtcttgat ggccttggtc accttggaat
   117241 cgcctttgcc tttggtttgg caatcgtggt ggcagcctac tcaatcggaa ctgtttcagg
   117301 tgctcacttg aacccggctg tttcgattgc tatgtttgta aacaaacgtt tgtcatcttc
   117361 agaacttgta aactacatcc ttggtcaggt tgttggagct ttcatcgctt ctggcgctgt
   117421 cttcttcctc ttggctaact caggtatgtc aactgctagt cttggtgaaa atgccttggc
   117481 aaacggtgtc actgtctttg gtggtttctt gtttgaagtc atcgcaactt tcttgtttgt
   117541 attggttatc atgactgtga cttcagaaag caagggcaat ggcgcgattg ctggtttggt
   117601 aatcggtttg tcattgatgg cgatgattct tgtcggattg aagattactg gactttcagt
   117661 aaacccagct cgtagcttgg caccagctgt cttggtaggc ggcgcagccc ttcaacaagt
   117721 ttggattttc atccttgcac caatcgctgg tggagttctt gcagcccttg ttgcaaaaaa
   117781 tttccttgga acagaagaat aattgaaact caaaaagcct tgctcctcat cttgaggaac
   117841 agggcttttt cgtatgatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc
   117901 cgtaggtatg gttactgact tcgtcagttc tatccacaac ctcaaaacag tgttttgagc
   117961 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagcaacct gcggctagtt
   118021 tcctagtttg ctctttgatt ttcattgagt attattaaga caatatgagg agaaagatga
   118081 aagaaaaagg attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca
   118141 gtatcggcct ggcctgtggg actatcggtg cgccctatgt gacacctgtt gagatgggct
   118201 tgatgagtct ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgtgg
   118261 ttcaagctcc tgtggcagct attgctatga cggtttttct aatcaacttg cgtctctttt
   118321 tgttgagttt acacgcatcg acttatttcc gtcataccag tctttggtac aatatcggta
   118381 tgtctagtat cttgacagat gagacctatg gcgttttgat gggtgaattg gcccatacag
   118441 acaaggtaaa tcctatgtgg atgcacggaa acaatcttaa cagctatgtg gcttggtttg
   118501 tggggacagt agtcggaacg gatctgggtg gcctgctacc aaatccagaa atctttggct
   118561 tggattttgc cctggttggg atgtttattg gtatttttgc ttcgcaattt cagatgatgc
   118621 aaagacggat tcctgtccgc aatctgctca ttatcctagc agttgttgcg gtgtccttct
   118681 ttttgctctt gacagtggtg tctcagtcac tagctgttct gtttgcgacg ctacttggtt
   118741 gtagcatggg ggtggtttta gatggtcagt aagtatcttt tattagcagt tattttctct
   118801 ggcttggtga cttggattct ccgtatgatt cccttcatct tagtcaagta taagggcttg
   118861 cctgcaatcg ttgagcgttt tttgaagttc ttgcccgttt ccattatctt tgccttgatt
   118921 ctttcaagcg tagtgacagg taaggttggg agccttcctc aaattaaatg gctagacttc
   118981 ttagccgtct ttccaacagc ttgggtagcc tttcgctacc gcaatctagt cggaacagtt
   119041 ctctttggag tggtcttgat tgccatcttg cgtttggtct tttaaattac ccataaaaaa
   119101 aacttatcac agagatagat atcatataat ggcgtaaatg ctctttttct gttaagatta
   119161 taaggtattc tattttggag gaaatgacat gaaaaaaatc gttaaatact catctcttgc
   119221 tgccctagga cttgttgctg caggtgtgct tgcggcttgc tcagggggtg ctaagaaaga
   119281 aggagaagca gctagcaaga aagaaatcat cgttgcaacc aatggatcac caaggccatt
   119341 tatctatgaa gaaaatggcg aattgactgg ttacgagatt gaagtcgttc gcgctatctt
   119401 taaagattct gacaaatatg atgtcaagtt tgaaaagaca gaatggtcag gtgtctttgc
   119461 tggtcttgac gctgaccgtt acaatatggc tgtcaacaat cttagctaca ctaaagaacg
   119521 tgcggagaaa tacctctatg ccgcaccaat tgcccaaaat cctaatgtcc ttgtcgtgaa
   119581 gaaagatgac tctagtatca agtctctcga tgatatcggt ggaaaatcga cggaagtcgt
   119641 tcaagccact acatcagcta agcagttaga agcatacaat gctgaacaca cggacaaccc
   119701 aactatcctt aactatacta aggcagactt ccaacaaatc atggtacgtt tgagcgatgg
   119761 acaatttgac tacaagattt ttgataaaat cggtgttgaa acagtgatca agaaccaagg
   119821 tttggacaac ttgaaagtta tcgaacttcc aagcgaccaa caaccgtacg tttacccact
   119881 tcttgctcaa ggtcaagatg agttgaaatc atttgtagac aaacgcatca aagaacttta
   119941 taaagatgga actcttgaaa aattgtctaa acaattcttc ggagacactt atctaccggc
   120001 agaagctgat attaaataat ttcttgaaat catccattct gagtaaggtg ggtggtttct
   120061 cagtttttag ggatatagtt ttaaactata tatctgatta tctaataaca atttgtgaaa
   120121 tcaaacaaat tgtgagatac tagtacggta ttatttttaa ggagaaagaa tcatgaaaat
   120181 caaaaaatgg cttggtctag cagcccttgc tacagtcgca ggtttggctc ttgcagcttg
   120241 cggaaactca gaaaagaaag cagacaatgc aacaactatc aaaatcgcaa ctgttaaccg
   120301 tagcggttct gaagaaaaac gttgggacaa aatccaagaa ttggttaaaa aagacggaat
   120361 taccttggaa tttacagagt tcacagacta ctcacaacca aacaaagcaa ctgctgatgg
   120421 cgaagtagat ttgaacgctt tccaacacta taacttcttg aacaactgga acaaagaaaa
   120481 cggaaaagac cttgtagcga ttgcagatac ttacatctct ccaatccgcc tttactcagg
   120541 tttgaatgga agtgccaaca agtacactaa agtagaagac atcccagcaa acggagaaat
   120601 cgctgtaccg aatgacgcta caaacgaaag ccgtgcgctt tatttgcttc aatcagctgg
   120661 cttgattaaa ttggatgttt ctggaactgc tcttgcaaca gttgccaaca tcaaagaaaa
   120721 tccaaagaac ttgaaaatca ctgaattgga cgctagccaa acagctcgtt cattgtcatc
   120781 agttgacgct gccgttgtaa acaatacctt cgttacagaa gcaaaattgg actacaagaa
   120841 atcacttttc aaagaacaag ctgatgaaaa ctcaaaacaa tggtacaaca tcattgttgc
   120901 aaaaaaagat tgggaaacat cacctaaggc tgatgctatc aagaaagtaa tcgcagctta
   120961 ccacacagat gacgtgaaaa aagttatcga agaatcatca gatggtttgg atcaaccagt
   121021 ttggtaataa gaaacaggga ggtgggagag aaaattccac ctcttgcttt tgtatagagt
   121081 atagattgta aagaagacta ttcgttcata gaaaggtaga gagaatatgg tttttcctag
   121141 cgaacaagaa cagattgaaa aatttgaaaa ggatcatgta gcccagcatt attttgaggt
   121201 tttgcgtacc ttgatttcta agaaatcagt ctttgcccag caggttggac tcaaggaagt
   121261 cgcaaattat ctgggtgaga ttttcaagcg tgttggagct gaagtggaga ttgatgagag
   121321 ctatacagcg ccctttgtca tggcacattt caagagttcg cgtccagatg ccaagacctt
   121381 gattttctat aaccactatg acactgtgcc agcggatggg gatcaggtct ggacagagga
   121441 tccttttacg ctttcggtcc gcaatggctt catgtatggg cgtggggttg atgacgacaa
   121501 gggtcatatc acagctcgct tgagtgcttt gagaaaatat atgcagcacc atgatgattt
   121561 acctgtcaat atcagcttta tcatggaggg agcggaggaa tcggcttcaa cagacctaga
   121621 taagtatttg gaaaagcatg cagacaaact ccgtggggcg gatttgttgg tctgggaaca
   121681 agggaccaaa aatgccttgg aacagctgga aatttctggt ggcaataagg ggattgtgac
   121741 ctttgatgcc aaggtaaaaa gcgctgatgt ggatatccac tcgagttatg gtggtgttgt
   121801 ggaatcagct ccttggtatc tcctccaagc cttacagtct cttcgtgccg cggatggccg
   121861 tatcttggtt gaaggcttgt acgaagaagt acaagagccc aatgaacgag aaatggcctt
   121921 gctagaaact tatggtcaac gaaacccaga ggaagttagt cggatttatg gattggagtt
   121981 gcctctctta caggaggagc ggatggcctt tctaaaacgt ttctttttcg agccagcgct
   122041 taatatcgaa ggaatccagt ctggttatca aggtcagggt gttaagacta ttttacctgc
   122101 agaagccagt gccaagctag aggttcgtct ggttccgggc ctagaaccgc atgatgttct
   122161 ggaaaaaatt cggaaacagc tagacaaaaa tggctttgat aaggtagaat tatactatac
   122221 cttgggagag atgagctatc gaagcgatat gagcgcacca gccattctca atgtgatcga
   122281 gttggccaag aaattctatc cacagggcgt ttcagtcttg ccgacgacag cggggacagg
   122341 acctatgcat acggtctttg atgccctaga ggtaccaatg gttgcattcg gtctaggaaa
   122401 tgccaatagc cgagaccacg gtggagatga aaatgtgcga atcgctgatt attacaccca
   122461 tatcgaatta gtagaggagc tgattagaag ctatgagtag agatattatc aagttagatc
   122521 agatcgatgt gacttttcac caaaagaaga gaaccatcac agcggttaag gatgtgacca
   122581 ttcacatcca agaaggggat atctacggaa tcgttggata ttctggagca gggaaatcaa
   122641 cccttgtacg ggtgattaat ctcttgcaaa aaccatctgc agggaaaatt accattgacg
   122701 acgatgtgat ttttgatggt aaggtcacct tgacggcaga gcagttgcgt cgtaaacgtc
   122761 aagatatcgg gatgattttc cagcatttta acctgatgag ccaaaagaca gcagaggaga
   122821 atgtagcctt tgcccttaaa cactctggac tcagcaagga agaaaagaag gctaaagtag
   122881 ctaagttgtt ggacttggtt ggtttggcag atcgtgctga aaactaccct tcacaactat
   122941 ctggagggca aaaacagcgt gtggcaattg cgcgtgcctt ggccaatgat ccaaaaatct
   123001 tgatttcaga cgagtcaact tctgcccttg accctaagac aaccaagcag attttggcct
   123061 tgttgcaaga tttgaaccaa aaattaggct tgactgttgt cttgattacg catgaaatgc
   123121 agattgtcaa agacattgcc aaccgtgttg cagttatgca ggatgggcat ttgattgaag
   123181 agggtagtgt gcttgaaatc ttctcaaacc ctaaacaacc tttgactcaa gactttatct
   123241 caacagctac aggtattgac gaagccatgg tcaaaatcga gaagcaagaa atcgtggaac
   123301 acttgtctga aaacagtctc ttggtgcaac tcaagtacgc tggagcttca acagacgagc
   123361 cacttttgaa tgaattgtac aagcattacc aagtaatggc taatattctc tatgggaata
   123421 tcgaaattct cgatggtact cctgttggag aattggtggt ggtcttgtca ggtgaaaaag
   123481 cagccttggc aggtgcccaa gaagccattc gtcaagcagg tgtacaacta aaagtattga
   123541 agggagtaca gtaagatgga atcattgatt caaacctatt taccaaatgt ctataagatg
   123601 ggttgggctg gtcaggcagg ctggggaacg gctatctact taactcttta tatgacagtt
   123661 ctttccttca ttatcggagg cttcttgggg ctagtggcag gtctctttct cgtcttgaca
   123721 gcgccaggtg gtgtcttgga gaataaagtc gtattctgga ttttagacaa aattacctca
   123781 atttttcgtg cggttccctt tatcatcctc ttggcaatct tgtcaccact ttctcacttg
   123841 attgttaaaa caagtatcgg gccaaatgca gcccttgtcc cactttcttt tgcagtcttt
   123901 gccttctttg cccgtcaggt gcaggttgtc ttggctgaat tggatggcgg tgtcattgag
   123961 gcggctcaag cgagcggagc gactttctgg gacatcgtgg gtgtttacct atcagaaggt
   124021 cttccagatt tgatccgtgt gacgactgtg accttgattt cccttgttgg ggaaacagct
   124081 atggccggtg cggttggagc tggtggtatc ggtaacgtag ccatcgctta tggatttaac
   124141 cgctacaatc acgatgtgac catcttggca accattatta tcattttgat tatctttgca
   124201 atccaattct tgggagattt cttgactaag aaattgagcc ataaataaaa aagagccgcg
   124261 tggctctttt taactgatca gattttctgg gcaaattttt tactcaaggc ttgtccaatc
   124321 aaggcaccca ctagggctcc gatgacaata cttgcgataa atagaaggac agttccaggg
   124381 tttggagcga ccatgatacg gtcgatatat tcttgggatt ttcctcttgc cagaagagta
   124441 gccatatagg ctttgggcgc aatccacata agcaagattg gtcctgttgt actaaaggcg
   124501 aaaataatga aagaaaggaa gttctttgtt ttgtccttgt attttcctaa atgagctact
   124561 ccatctgcta ggaggccaca gataattcca ggaaggaagg aaccagcacc gtgtttagtt
   124621 cccaagaaaa agagggcaat gacaaggccg atagtggtaa tggctccaaa gcgcggaact
   124681 tttgcgacta ggatcatata gacgctaccg ccgacaaggg cagtaaaggc aggcgcataa
   124741 aacatgtttc cagtttggtc aaagagattg cccaaaagga caccaatccc catgcagagg
   124801 aagtaaagaa ctgcaaaaag cagtgtagtt aagatagatt tcttcatgaa ttgtctcctg
   124861 ataatttttt cacaattctc attttatcat ggtttggtgg gattgtaaat ggatactaga
   124921 agtttttgaa aacgcttgaa atatgatata atggtttcat agttattttt aggggaatat
   124981 catgggtaga tttttagact ttgtctttaa tcgtttcttt ttagggatga ttgcgacagc
   125041 cttcttttgg ctattaactt tagcaggagg gattatcctt ggtctagcgc cggctagtgc
   125101 caccttgatg agcttatatg cagaacatgg ttatagcttt cgggaataca gtttgaagga
   125161 ggcttggtct ctttacaagc aaaattttgt ctcaagcaac ctgattttct atagcttttt
   125221 aggtgtgggt ctagttttga cctatggttt gtatctcttg gtgcaattgc ctcatcagac
   125281 cattgttcat ttgattgcga cccttttgaa tgtcctagta gttgccctga tctttttggc
   125341 ttatacagta tctttaaaat tacaagttta ttttgccttg tcctatcgaa atagtctcaa
   125401 attatccttg attggcatct ttatgagtct agcagctgtg gctaaggttc tccttgggac
   125461 tgtgctactt gtagcaattg gttattatat gcctgccctg ctattttttg taggaattgg
   125521 gatgtggcat ttctttatca gtgatatgtt ggaacctgtc tatgaaatca tccatgaaaa
   125581 attggcgaca aaatagaatg aagcagtttt ggctacatac gcttctaaga acctatagtt
   125641 cagtgatgat cattatcatt gcgagttttg caatcttact ctcttacgct gactgggatt
   125701 cacgtgaaaa ggaagcccag agagtagccc agcgtgtaac tgctagaaca gtgagtgaaa
   125761 ttgaatatta ccatagagag tcaacccaga tagctcaggc tttagttgaa aatcaagctc
   125821 gtattgaggg aatctataaa tactttagcc ttagcatgcc agactatttt tactggcaat
   125881 tagagcggaa agcttcgcct tatatatcag tctctctgta tgaaaatgtt gatgacctct
   125941 atgttcgaaa tgattttgta actggagtgg ccattgcttt tcaagattac aaggaagtct
   126001 atgtttctac taaagacaaa cgtagtggag aaaaaatcag ggctgaggat ttcaaaccag
   126061 caggaaatag ttttgccatt ccggtgtcag atccagtgtc agatcaagat ttaggagtga
   126121 tttacatctc cttggatcct gctgttttat accatgccat tgataatact agaggtcata
   126181 ctccgatggc agtaacagtg acctcacctt ttgatacgga gatttttcat attggtgaga
   126241 cagttgataa ggagagtgaa aattggctag ttggcttaac ttctcatgga tatcaggttc
   126301 aggtggcagt tcctaaaaac tttgttttac aaggaacagt gactagctct gctttgattg
   126361 tgggtttgag ccttctcttt attgtcattc tttatctgac tttgaggcag acttttgcta
   126421 attaccaaaa gcaggtagtg gatttagtag aatccattca agtcattgct caaggcgaag
   126481 aggggcgtcg gattgacatt tccgagaaag atcaggaatt actcctaatc gcggagacga
   126541 ccaatgatat gttggatcga ttggaaaaga atatccatga tatttaccag ttagagctta
   126601 gtcaaaaaga tgccaatatg cgagccttgc aggcgcaaat caatcctcat tttatgtata
   126661 atacgctgga gttcttgcgc atgtatgcag ttatgcagag tcaagatgag ttggcagata
   126721 tcatttatga attcagtagt ctcttgcgta acaatatttc cgacgaaaga gagaccctcc
   126781 tcaaacagga attagaattt tgccgtaaat acagctatct ctgcatggtt cgctatccca
   126841 agtccattgc ctatggtttc aagatagatc cagagttaga gaatatgaag attcccaagt
   126901 ttaccttgca accgctggta gaaaactatt tcgcgcatgg tgttgaccac aggcggacag
   126961 ataatgtgat tagcatcaag gctcttaaac aggatggttt tgtggaaatt ttggtggtcg
   127021 ataatggtag aggaatgtcg gctgaaaagt tggcaaatat ccgagaaaaa ttaagtcaga
   127081 aatattttga acaccaagtc agctacagtg atcaaaggca gtctatcggg attgtcaatg
   127141 tacacgagcg ttttgtgctc tattttggag accgctatgc cattactata gagtctgcag
   127201 agcaagccgg tgttcagtat cgtattacaa ttcaagatga gtagaaaggg agaaaatgta
   127261 taaagtatta ttagtagatg atgagtacat ggtgacagaa ggtctgaagc gtttgattcc
   127321 ctttgataag tgggatatgg aggtcgtcgc aacagccagt catgccgatg aagctctaga
   127381 atatgttcag gaaaatcctg tcgatgtcat catttccgat gtcaatatgc cagacaaaac
   127441 agggcttgat atgattcggg agatgaaaga gatcttacca gatgctgcct atatcctgct
   127501 ctcaggttat caggagtttg attatgtaaa aagagcaatg aaccttagtg tggtggacta
   127561 tttggtcaag cctgttgata aggtagagct gggaaatctg ctggagaaga ttgcaggtca
   127621 gatcggcgag agagggaaga aaagtcagac tcttagtcaa gaattagacg aggctggatt
   127681 tgttagttat ttaggggata aggagaattg gtggataggt ctatccaagg aaaaacaagg
   127741 ttccttcacc attccctact atgtcttggg tcaagactgg cagattttca tttctgatca
   127801 acccctagat ggcttagtcg ttactccctt tgaagctccc tatcaagaac actttgaacg
   127861 ctggaagcta aatgctgaga aaaccctctt ttacggttct gtaaatttgc agcagtctga
   127921 gagtctcttt gcctattacg aaccgattta tagggttatc attcagggaa atctcaatca
   127981 aatcgtagaa gagttaaatc tcttggagaa ggtagttctt gaaaatacgc cgcgtgttcc
   128041 gattactaaa cagcttttta ttcagtttgt catggatgtt ttccatttat ttgaacatct
   128101 caaagctgat gacctgacag acatcgtcaa aaccattcat gctattcaat ccttcgatga
   128161 attggttcct tatatcaagg aaactctgac cagctttttc ggtcaatacc gtatgaatga
   128221 aaatgtggtc agtgtgctgg aagtcattgg tcgtgattac caaaaagagc tttccctcaa
   128281 ggatatcagt aaggctctct ttatcaatcc tgtctatcta gggcagttga ttaagcgtga
   128341 aaccgattcg acttttgcag agttactaaa caaacaacgt attaaggctg cccaacaact
   128401 tttgctttca actagtgaca gcatcgaaga tatttgttat gctgttggtt acagtaacct
   128461 tggatatttc tataaagttt tccgaaaatt gtgcggaaaa tcgccaaaag cctaccgaaa
   128521 acaggtagaa actatactat aagatttgta ttcctttaca aaatgtgcta taatattatc
   128581 aggaggttct atcatgaaaa agaaaccaat ttatctatgg gtcttgctaa tcttgtctgc
   128641 ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta aagaagccct
   128701 tcgtgctgct cagaaacaag ttgcaggggt caatgctcag caattagaag accagcttaa
   128761 ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt tgattgtgct
   128821 atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt tgcaatatgc
   128881 aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt atggctatgt
   128941 tggtttacaa gacgctgtgc agttggttca agatgagacc atgcgtttga cagtgagtat
   129001 tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc tagcccttgt
   129061 cttctataag atgtggcgac aacagaaagc cttggcagaa gaagaggaaa cagaagagct
   129121 tgcctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg ttttttgatt
   129181 atagataaaa tcatggaggt acatatgaag acaatttctt tagtttatat tagtttgagt
   129241 ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca gtacaaaggg
   129301 attgaggttc aaaagattca tatcaaggat ttagtcaagg aaggcaaaaa tttctatgaa
   129361 atggaccatc cctatgtcgc ttttttgccg acctatctcg aaggtgggaa tggcgtggat
   129421 aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta tggtaacaat
   129481 gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa ccaatactgc
   129541 ctaacagcca agcaatacag tcaacgcttt ggcttccctg tattggctga ctttgaaatg
   129601 cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt gtatgagttg
   129661 gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct agtcgcaggt
   129721 tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag agattctcga
   129781 atagtataaa gttcttataa gaggtggttg aagttgttca actgtttttt gagtataaac
   129841 agtctttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt cttatgcttt
   129901 ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt catctcgcgc
   129961 ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg gcgaagccaa
   130021 agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga tttttgtttt
   130081 cacgcgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg aaagagccaa
   130141 tcatggcaaa gcggagcatg gttgaaacct gaccagcgaa gaacttgata atgacgatac
   130201 cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattgtcc tctttttgac
   130261 tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata acagttataa
   130321 ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac cattcgccaa
   130381 gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca gcttcaaccg
   130441 cctgccctgt aggatactga atcagtgctc ccagtgccac aaagaagacg gctaggatag
   130501 ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta aagttgacgg
   130561 tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata ggagccggca
   130621 tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt gtcttctcga
   130681 caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgca agaacagtcg
   130741 caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg tagcctccaa
   130801 agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta atgctaagtc
   130861 caatcattgg gaaggcactg gcgatgatag ctgagcacag aatggcaaca ccagccgtgt
   130921 tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt tttccttttt
   130981 cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca ccaaaacgga
   131041 aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac caaccgtaag
   131101 aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca gttgccatta
   131161 ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt aaggaaatag
   131221 cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata tgtaatctat
   131281 attctacaaa aaattttgga aaaatgcaag agtattttga aaaaagatag aaaatttaca
   131341 aagaaaatct gaaataactg ttatgatata gaggattgaa actagaatag tacacctctg
   131401 cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttatcc tgttcttatt
   131461 tcatttcact atagtaaggt gcagcaggat aaagaaaaac cgagaagttt ctttctcgga
   131521 tttgcttatt atgaggttcc tattttctat gctccaagag ttgattgatg tgatctactt
   131581 ttttagcctc tcttttatag agaatagccc agatgatgag atagacaatc gcaaactcga
   131641 taatgagctg gaggtagaaa atccagtgga aagggaacca accagcaaga gttgctagtg
   131701 ggacaaagcc agccagcata aggaagaaat gagtcagagt ggcacgaagc atgctccagt
   131761 cacggctaaa taagcggttg ccaaagttga agagcatacc gatggttgcc cagataagtg
   131821 tgcagtagag caagaccagg gcaccgtgaa cctgatgctg atccatcact tggccgatga
   131881 gagagtaggg atttagtggt gcgtaggtat ttggtgcata aatgagtgaa aagaggatag
   131941 agaggatgag gccgataaga acaccggcag ctgcatcgtg aaatacttgt tttttcatag
   132001 ttctaatttc tccttgatgg tttttagata acggcgtgaa gagtaggtga agctttcgtt
   132061 tttcaagaaa atttctatca gaccgtttgg cgtgagcttg aggtgagaga tggaatcgat
   132121 attgatgatt tctgattggg aaatttggat aaaattggtt ggcaagagtt taagaacctg
   132181 atagagtcgc aaatcaatgc tgtaggtctg actcgcggtt tctgctagaa ccttccgatt
   132241 ctcgatatag aagcgctgaa tcttgccaat ctcaactaga tagacctgat catcgatttt
   132301 ccctttgatt ttttctcttt ggtccagatt ttctgcgaac tcgatgactt tctgaacttt
   132361 atctgtcggc tgaggtgctt ggacaatcag cttttcctcc tcgtaagtct cactaatctg
   132421 taattctact ttcataaatt tctctccttg tttttcatac aaaattaatc tcacttcttg
   132481 tacaccttta ttaatactct tcaaaaatct cttcaaacca cgtcagcgtc gtcttgccgt
   132541 aggatagttg ttgactttgt cagttttatc tacaacctca aaacagtgtt ttgagctgtc
   132601 tgcgcctagc tttctagttt g
//
LOCUS       DAVDHC010000002       128607 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVDHC010000002 DAVDHC010000000
VERSION     DAVDHC010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 128607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 128607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..128607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.002"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(181..1929)
                     /locus_tag="VUR43_000140"
     CDS             complement(181..1929)
                     /locus_tag="VUR43_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411893.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1931..3655)
                     /locus_tag="VUR43_000141"
     CDS             complement(1931..3655)
                     /locus_tag="VUR43_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411894.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRYILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISTELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3713..4651)
                     /gene="msrB"
                     /locus_tag="VUR43_000142"
     CDS             complement(3713..4651)
                     /gene="msrB"
                     /locus_tag="VUR43_000142"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET5411895.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4946..5815)
                     /locus_tag="VUR43_000143"
     CDS             complement(4946..5815)
                     /locus_tag="VUR43_000143"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET5411896.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(5817..7103)
                     /locus_tag="VUR43_000144"
     CDS             complement(5817..7103)
                     /locus_tag="VUR43_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET5411897.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITCALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7254..7991)
                     /gene="mecA"
                     /locus_tag="VUR43_000145"
     CDS             complement(7254..7991)
                     /gene="mecA"
                     /locus_tag="VUR43_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET5411898.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8191..9225)
                     /locus_tag="VUR43_000146"
     CDS             complement(8191..9225)
                     /locus_tag="VUR43_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET5411899.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9253..10686)
                     /locus_tag="VUR43_000147"
     CDS             complement(9253..10686)
                     /locus_tag="VUR43_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET5411900.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(10702..11688)
                     /locus_tag="VUR43_000148"
     CDS             complement(10702..11688)
                     /locus_tag="VUR43_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5411901.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11690..12793)
                     /locus_tag="VUR43_000149"
     CDS             complement(11690..12793)
                     /locus_tag="VUR43_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET5411902.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12783..13628)
                     /locus_tag="VUR43_000150"
     CDS             complement(12783..13628)
                     /locus_tag="VUR43_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET5411903.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13907..15181)
                     /gene="psr"
                     /locus_tag="VUR43_000151"
     CDS             complement(13907..15181)
                     /gene="psr"
                     /locus_tag="VUR43_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET5411904.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15178..16026)
                     /gene="pheA"
                     /locus_tag="VUR43_000152"
     CDS             complement(15178..16026)
                     /gene="pheA"
                     /locus_tag="VUR43_000152"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET5411905.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAENPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(16023..16499)
                     /locus_tag="VUR43_000153"
     CDS             complement(16023..16499)
                     /locus_tag="VUR43_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET5411906.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIENRLGMSIANFFA
                     EKGETAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLRADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16492..17775)
                     /gene="aroA"
                     /locus_tag="VUR43_000154"
     CDS             complement(16492..17775)
                     /gene="aroA"
                     /locus_tag="VUR43_000154"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET5411907.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLINPNSHLVLQNVGINETRTGIIDVIRAMGGKL
                     EVTEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17867..18205)
                     /locus_tag="VUR43_000155"
     CDS             complement(17867..18205)
                     /locus_tag="VUR43_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET5411908.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18216..19319)
                     /locus_tag="VUR43_000156"
     CDS             complement(18216..19319)
                     /locus_tag="VUR43_000156"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET5411909.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19329..20495)
                     /gene="aroC"
                     /locus_tag="VUR43_000157"
     CDS             complement(19329..20495)
                     /gene="aroC"
                     /locus_tag="VUR43_000157"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET5411910.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20505..21572)
                     /locus_tag="VUR43_000158"
     CDS             complement(20505..21572)
                     /locus_tag="VUR43_000158"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET5411911.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21591..22445)
                     /locus_tag="VUR43_000159"
     CDS             complement(21591..22445)
                     /locus_tag="VUR43_000159"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET5411912.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(22435..23112)
                     /locus_tag="VUR43_000160"
     CDS             complement(22435..23112)
                     /locus_tag="VUR43_000160"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET5411913.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23109..24272)
                     /locus_tag="VUR43_000161"
     CDS             complement(23109..24272)
                     /locus_tag="VUR43_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET5411914.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24957..26591)
                     /locus_tag="VUR43_000162"
     CDS             complement(24957..26591)
                     /locus_tag="VUR43_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5411915.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(26572..27321)
                     /locus_tag="VUR43_000163"
     CDS             complement(26572..27321)
                     /locus_tag="VUR43_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411916.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            27500..28954
                     /locus_tag="VUR43_000164"
     CDS             27500..28954
                     /locus_tag="VUR43_000164"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET5411917.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(29044..31662)
                     /gene="alaS"
                     /locus_tag="VUR43_000165"
     CDS             complement(29044..31662)
                     /gene="alaS"
                     /locus_tag="VUR43_000165"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET5411918.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(31684..32169)
                     /locus_tag="VUR43_000166"
     CDS             complement(31684..32169)
                     /locus_tag="VUR43_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET5411919.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32444..32683)
                     /locus_tag="VUR43_000167"
     CDS             complement(32444..32683)
                     /locus_tag="VUR43_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5411920.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(32928..33998)
                     /locus_tag="VUR43_000168"
     CDS             complement(32928..33998)
                     /locus_tag="VUR43_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5411921.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33995..34768)
                     /locus_tag="VUR43_000169"
     CDS             complement(33995..34768)
                     /locus_tag="VUR43_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5411922.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34765..35571)
                     /locus_tag="VUR43_000170"
     CDS             complement(34765..35571)
                     /locus_tag="VUR43_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5411923.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35552..36709)
                     /locus_tag="VUR43_000171"
     CDS             complement(35552..36709)
                     /locus_tag="VUR43_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411924.1"
                     /translation="MKKSIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36870..37775)
                     /gene="murB"
                     /locus_tag="VUR43_000172"
     CDS             complement(36870..37775)
                     /gene="murB"
                     /locus_tag="VUR43_000172"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET5411925.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(37887..38639)
                     /locus_tag="VUR43_000173"
     CDS             complement(37887..38639)
                     /locus_tag="VUR43_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET5411926.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38649..39380)
                     /gene="budA"
                     /locus_tag="VUR43_000174"
     CDS             complement(38649..39380)
                     /gene="budA"
                     /locus_tag="VUR43_000174"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET5411927.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIGEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39522..40793
                     /locus_tag="VUR43_000175"
     CDS             39522..40793
                     /locus_tag="VUR43_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET5411928.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40813..41628)
                     /locus_tag="VUR43_000176"
     CDS             complement(40813..41628)
                     /locus_tag="VUR43_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET5411929.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(41785..42438)
                     /gene="phoU"
                     /locus_tag="VUR43_000177"
     CDS             complement(41785..42438)
                     /gene="phoU"
                     /locus_tag="VUR43_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET5411930.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42450..43208)
                     /gene="pstB"
                     /locus_tag="VUR43_000178"
     CDS             complement(42450..43208)
                     /gene="pstB"
                     /locus_tag="VUR43_000178"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET5411931.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43221..44024)
                     /gene="pstB"
                     /locus_tag="VUR43_000179"
     CDS             complement(43221..44024)
                     /gene="pstB"
                     /locus_tag="VUR43_000179"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET5411932.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(44035..44919)
                     /gene="pstA"
                     /locus_tag="VUR43_000180"
     CDS             complement(44035..44919)
                     /gene="pstA"
                     /locus_tag="VUR43_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET5411933.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44909..45826)
                     /gene="pstC"
                     /locus_tag="VUR43_000181"
     CDS             complement(44909..45826)
                     /gene="pstC"
                     /locus_tag="VUR43_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET5411934.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45826..46704)
                     /gene="pstS"
                     /locus_tag="VUR43_000182"
     CDS             complement(45826..46704)
                     /gene="pstS"
                     /locus_tag="VUR43_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET5411935.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKELGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47278..48582)
                     /locus_tag="VUR43_000183"
     CDS             complement(47278..48582)
                     /locus_tag="VUR43_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET5411936.1"
                     /translation="MQFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGHLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48583..49356)
                     /locus_tag="VUR43_000184"
     CDS             complement(48583..49356)
                     /locus_tag="VUR43_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET5411937.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRSLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRSVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49346..49624)
                     /locus_tag="VUR43_000185"
     CDS             complement(49346..49624)
                     /locus_tag="VUR43_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET5411938.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(49624..50025)
                     /locus_tag="VUR43_000186"
     CDS             complement(49624..50025)
                     /locus_tag="VUR43_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET5411939.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50235..50852)
                     /locus_tag="VUR43_000187"
     CDS             complement(50235..50852)
                     /locus_tag="VUR43_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET5411940.1"
                     /translation="MKTKLIFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLCLKSRRK"
     gene            complement(50842..51615)
                     /locus_tag="VUR43_000188"
     CDS             complement(50842..51615)
                     /locus_tag="VUR43_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET5411941.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51626..52363)
                     /locus_tag="VUR43_000189"
     CDS             complement(51626..52363)
                     /locus_tag="VUR43_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET5411942.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52368..53498)
                     /locus_tag="VUR43_000190"
     CDS             complement(52368..53498)
                     /locus_tag="VUR43_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET5411943.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53582..53971)
                     /locus_tag="VUR43_000191"
     CDS             complement(53582..53971)
                     /locus_tag="VUR43_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET5411944.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53987..54370)
                     /locus_tag="VUR43_000192"
     CDS             complement(53987..54370)
                     /locus_tag="VUR43_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET5411945.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54371..55159)
                     /locus_tag="VUR43_000193"
     CDS             complement(54371..55159)
                     /locus_tag="VUR43_000193"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET5411946.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYHQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55152..56087)
                     /locus_tag="VUR43_000194"
     CDS             complement(55152..56087)
                     /locus_tag="VUR43_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET5411947.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56217..56393)
                     /locus_tag="VUR43_000195"
     CDS             complement(56217..56393)
                     /locus_tag="VUR43_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET5411948.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56534..57241)
                     /locus_tag="VUR43_000196"
     CDS             complement(56534..57241)
                     /locus_tag="VUR43_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET5411949.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57392..58420
                     /gene="queA"
                     /locus_tag="VUR43_000197"
     CDS             57392..58420
                     /gene="queA"
                     /locus_tag="VUR43_000197"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET5411950.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(59089..60216)
                     /locus_tag="VUR43_000198"
     CDS             complement(59089..60216)
                     /locus_tag="VUR43_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET5411951.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDVDNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(60931..61482)
                     /locus_tag="VUR43_000199"
     CDS             complement(60931..61482)
                     /locus_tag="VUR43_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5411952.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61880..62704)
                     /gene="nadE"
                     /locus_tag="VUR43_000200"
     CDS             complement(61880..62704)
                     /gene="nadE"
                     /locus_tag="VUR43_000200"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET5411953.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62701..64161)
                     /locus_tag="VUR43_000201"
     CDS             complement(62701..64161)
                     /locus_tag="VUR43_000201"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET5411954.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMHNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILIYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64277..64765)
                     /locus_tag="VUR43_000202"
     CDS             complement(64277..64765)
                     /locus_tag="VUR43_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5411955.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64755..64964)
                     /locus_tag="VUR43_000203"
     CDS             complement(64755..64964)
                     /locus_tag="VUR43_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5411956.1"
                     /translation="MVKNLKLKLARVELDLTQGQLADAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDKLFWEEEDEK"
     gene            complement(65350..66078)
                     /locus_tag="VUR43_000204"
     CDS             complement(65350..66078)
                     /locus_tag="VUR43_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5411957.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVTSNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(66094..66885)
                     /locus_tag="VUR43_000205"
     CDS             complement(66094..66885)
                     /locus_tag="VUR43_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5411958.1"
                     /translation="MNFALNKGEIVGLAGRNGVGKSTLMKILVQNNKPTSGNIISSDN
                     VGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQEIFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67321..68049)
                     /locus_tag="VUR43_000206"
                     /pseudo
     CDS             complement(67321..68049)
                     /locus_tag="VUR43_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(68309..68620)
                     /locus_tag="VUR43_000207"
     CDS             complement(68309..68620)
                     /locus_tag="VUR43_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5411959.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCLFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(68635..69921)
                     /locus_tag="VUR43_000208"
     CDS             complement(68635..69921)
                     /locus_tag="VUR43_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET5411960.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFATKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDAVQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQSGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            70545..70727
                     /locus_tag="VUR43_000209"
     CDS             70545..70727
                     /locus_tag="VUR43_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET5411961.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLCFNEKFGTENT"
     gene            70737..71102
                     /locus_tag="VUR43_000210"
     CDS             70737..71102
                     /locus_tag="VUR43_000210"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET5411962.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            71099..72289
                     /locus_tag="VUR43_000211"
     CDS             71099..72289
                     /locus_tag="VUR43_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET5411963.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSIRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGDYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(72365..73927)
                     /gene="guaA"
                     /locus_tag="VUR43_000212"
     CDS             complement(72365..73927)
                     /gene="guaA"
                     /locus_tag="VUR43_000212"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET5411964.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            74069..74767
                     /locus_tag="VUR43_000213"
     CDS             74069..74767
                     /locus_tag="VUR43_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5411965.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(74810..75706)
                     /locus_tag="VUR43_000214"
     CDS             complement(74810..75706)
                     /locus_tag="VUR43_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET5411966.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(75715..76650)
                     /locus_tag="VUR43_000215"
     CDS             complement(75715..76650)
                     /locus_tag="VUR43_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET5411967.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(76647..77372)
                     /locus_tag="VUR43_000216"
     CDS             complement(76647..77372)
                     /locus_tag="VUR43_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET5411968.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESIEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(77456..78091)
                     /locus_tag="VUR43_000217"
     CDS             complement(77456..78091)
                     /locus_tag="VUR43_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET5411969.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(78093..78920)
                     /locus_tag="VUR43_000218"
     CDS             complement(78093..78920)
                     /locus_tag="VUR43_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5411970.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAKTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINTLFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(78942..79868)
                     /locus_tag="VUR43_000219"
                     /pseudo
     CDS             complement(78942..79868)
                     /locus_tag="VUR43_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809127.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            80519..81130
                     /locus_tag="VUR43_000220"
     CDS             80519..81130
                     /locus_tag="VUR43_000220"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET5411971.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            81175..81903
                     /gene="rlmB"
                     /locus_tag="VUR43_000221"
     CDS             81175..81903
                     /gene="rlmB"
                     /locus_tag="VUR43_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET5411972.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(81942..82853)
                     /gene="trxB"
                     /locus_tag="VUR43_000222"
     CDS             complement(81942..82853)
                     /gene="trxB"
                     /locus_tag="VUR43_000222"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET5411973.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVTGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRSFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(82919..83143)
                     /locus_tag="VUR43_000223"
     CDS             complement(82919..83143)
                     /locus_tag="VUR43_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET5411974.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(83221..83964)
                     /locus_tag="VUR43_000224"
     CDS             complement(83221..83964)
                     /locus_tag="VUR43_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5411975.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(83964..84764)
                     /locus_tag="VUR43_000225"
     CDS             complement(83964..84764)
                     /locus_tag="VUR43_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5411976.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAVFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDIVQTDVKGDLR"
     gene            complement(84922..85278)
                     /locus_tag="VUR43_000226"
     CDS             complement(84922..85278)
                     /locus_tag="VUR43_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET5411977.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(85272..85802)
                     /locus_tag="VUR43_000227"
     CDS             complement(85272..85802)
                     /locus_tag="VUR43_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET5411978.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(85802..86296)
                     /locus_tag="VUR43_000228"
     CDS             complement(85802..86296)
                     /locus_tag="VUR43_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5411979.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            86431..86877
                     /locus_tag="VUR43_000229"
     CDS             86431..86877
                     /locus_tag="VUR43_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET5411980.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            86874..87521
                     /locus_tag="VUR43_000230"
     CDS             86874..87521
                     /locus_tag="VUR43_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET5411981.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     NQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(87542..88123)
                     /gene="pdxT"
                     /locus_tag="VUR43_000231"
     CDS             complement(87542..88123)
                     /gene="pdxT"
                     /locus_tag="VUR43_000231"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET5411982.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(88124..88999)
                     /gene="pdxS"
                     /locus_tag="VUR43_000232"
     CDS             complement(88124..88999)
                     /gene="pdxS"
                     /locus_tag="VUR43_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET5411983.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(89151..90530)
                     /locus_tag="VUR43_000233"
     CDS             complement(89151..90530)
                     /locus_tag="VUR43_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET5411984.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            90824..91747
                     /locus_tag="VUR43_000234"
     CDS             90824..91747
                     /locus_tag="VUR43_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET5411985.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            91807..92412
                     /locus_tag="VUR43_000235"
     CDS             91807..92412
                     /locus_tag="VUR43_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET5411986.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            92431..93675
                     /locus_tag="VUR43_000236"
     CDS             92431..93675
                     /locus_tag="VUR43_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET5411987.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(93792..94049)
                     /locus_tag="VUR43_000237"
     CDS             complement(93792..94049)
                     /locus_tag="VUR43_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET5411988.1"
                     /translation="MDPKKIARINELAKKKKTEGLTLEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(94091..96127)
                     /locus_tag="VUR43_000238"
     CDS             complement(94091..96127)
                     /locus_tag="VUR43_000238"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET5411989.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(96339..97256)
                     /gene="glyQ"
                     /locus_tag="VUR43_000239"
     CDS             complement(96339..97256)
                     /gene="glyQ"
                     /locus_tag="VUR43_000239"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET5411990.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(97449..98209)
                     /locus_tag="VUR43_000240"
                     /pseudo
     CDS             complement(97449..98209)
                     /locus_tag="VUR43_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
     gene            complement(98482..99324)
                     /locus_tag="VUR43_000241"
     CDS             complement(98482..99324)
                     /locus_tag="VUR43_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET5411991.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKLLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEEVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(99438..100829)
                     /locus_tag="VUR43_000242"
     CDS             complement(99438..100829)
                     /locus_tag="VUR43_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET5411992.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEKEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(101064..101441)
                     /locus_tag="VUR43_000243"
     CDS             complement(101064..101441)
                     /locus_tag="VUR43_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET5411993.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREDDTHQSYKHIAPV
                     YAIAIVDSNYFSDDLASHSFIVK"
     gene            101674..102651
                     /locus_tag="VUR43_000244"
     CDS             101674..102651
                     /locus_tag="VUR43_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET5411994.1"
                     /translation="MLKLGIIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIKFEAEK"
     gene            102648..103730
                     /locus_tag="VUR43_000245"
     CDS             102648..103730
                     /locus_tag="VUR43_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5411995.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(103796..104835)
                     /locus_tag="VUR43_000246"
                     /pseudo
     CDS             complement(103796..104835)
                     /locus_tag="VUR43_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(105219..106415)
                     /gene="tuf"
                     /locus_tag="VUR43_000247"
     CDS             complement(105219..106415)
                     /gene="tuf"
                     /locus_tag="VUR43_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET5411996.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(107326..108195)
                     /locus_tag="VUR43_000248"
     CDS             complement(107326..108195)
                     /locus_tag="VUR43_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET5411997.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(108419..109096)
                     /locus_tag="VUR43_000249"
     CDS             complement(108419..109096)
                     /locus_tag="VUR43_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5411998.1"
                     /translation="MVSKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLASLVLGFF
                     KKKEDEK"
     gene            complement(109054..110133)
                     /locus_tag="VUR43_000250"
     CDS             complement(109054..110133)
                     /locus_tag="VUR43_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET5411999.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDIVEPSRTVVEKIIPKLNIPEEEKKKKTSELAE
                     LISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKEGSQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(110244..110498)
                     /locus_tag="VUR43_000251"
     CDS             complement(110244..110498)
                     /locus_tag="VUR43_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412000.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPIWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(110838..111371)
                     /locus_tag="VUR43_000252"
     CDS             complement(110838..111371)
                     /locus_tag="VUR43_000252"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET5412001.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(111358..111573)
                     /locus_tag="VUR43_000253"
     CDS             complement(111358..111573)
                     /locus_tag="VUR43_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5412002.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(111540..111683)
                     /locus_tag="VUR43_000254"
     CDS             complement(111540..111683)
                     /locus_tag="VUR43_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET5412003.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            111917..113635
                     /locus_tag="VUR43_000255"
     CDS             111917..113635
                     /locus_tag="VUR43_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET5412004.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEKLGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNETAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            113746..114093
                     /locus_tag="VUR43_000256"
     CDS             113746..114093
                     /locus_tag="VUR43_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET5412005.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     ADTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(114372..115208)
                     /locus_tag="VUR43_000257"
     CDS             complement(114372..115208)
                     /locus_tag="VUR43_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5412006.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(115221..115850)
                     /locus_tag="VUR43_000258"
     CDS             complement(115221..115850)
                     /locus_tag="VUR43_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5412007.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(115860..116501)
                     /locus_tag="VUR43_000259"
     CDS             complement(115860..116501)
                     /locus_tag="VUR43_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5412008.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(116647..117876)
                     /locus_tag="VUR43_000260"
     CDS             complement(116647..117876)
                     /locus_tag="VUR43_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET5412009.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLVL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(117866..119032)
                     /locus_tag="VUR43_000261"
     CDS             complement(117866..119032)
                     /locus_tag="VUR43_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET5412010.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKINRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            119176..120189
                     /locus_tag="VUR43_000262"
     CDS             119176..120189
                     /locus_tag="VUR43_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET5412011.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDSVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(120234..120653)
                     /locus_tag="VUR43_000263"
     CDS             complement(120234..120653)
                     /locus_tag="VUR43_000263"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET5412012.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(120664..122070)
                     /gene="atpD"
                     /locus_tag="VUR43_000264"
     CDS             complement(120664..122070)
                     /gene="atpD"
                     /locus_tag="VUR43_000264"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET5412013.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(122156..123034)
                     /locus_tag="VUR43_000265"
     CDS             complement(122156..123034)
                     /locus_tag="VUR43_000265"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET5412014.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(123050..124555)
                     /locus_tag="VUR43_000266"
     CDS             complement(123050..124555)
                     /locus_tag="VUR43_000266"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET5412015.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENAMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(124570..125106)
                     /locus_tag="VUR43_000267"
     CDS             complement(124570..125106)
                     /locus_tag="VUR43_000267"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET5412016.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(125106..125600)
                     /gene="atpF"
                     /locus_tag="VUR43_000268"
     CDS             complement(125106..125600)
                     /gene="atpF"
                     /locus_tag="VUR43_000268"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET5412017.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(125614..126330)
                     /gene="atpB"
                     /locus_tag="VUR43_000269"
     CDS             complement(125614..126330)
                     /gene="atpB"
                     /locus_tag="VUR43_000269"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET5412018.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(126365..126565)
                     /locus_tag="VUR43_000270"
     CDS             complement(126365..126565)
                     /locus_tag="VUR43_000270"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET5412019.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(126640..127647)
                     /locus_tag="VUR43_000271"
     CDS             complement(126640..127647)
                     /locus_tag="VUR43_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET5412020.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHEKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRPEAINLRLENGHCEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            complement(128093..128491)
                     /locus_tag="VUR43_000272"
     CDS             complement(128093..128491)
                     /locus_tag="VUR43_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412021.1"
                     /translation="MENKESHKSQEIGNLIRVHNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSELLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT        38460 a        28437 c        23485 g        38225 t
ORIGIN      
        1 ctgacttcgt cagtcttatc tacaacctca aagctgtgct ttgagcaacc tacggctagc
       61 ttcctagttt gctctttgat tttcattgag tattacagtg aacaattttt ctagctattg
      121 taacaaaaaa gtcactcgaa ggcaactttt ttcgtccata aactttcaaa agagaatggc
      181 ttattcagaa ctaaaagccg cagctttttg catttggtaa tacttaccct ttctatccat
      241 gagttcttga tggttaccat attcaacaat atcaccatct actaagacaa gaattaaatc
      301 cgcatcctga atggttgaca aacggtgagc aatgatgaag cttgtgcggc ccttcatgag
      361 ttttgcaaag gcatcctgta ccagcacttc tgtccgtgta tcaatggaag aagttgcctc
      421 gtctaagata agaatctttg gaatagccag aaagactcgg gctatggtca agagctgagc
      481 ttggccgaca gagagagatt ctccagcatt ttccaacttg gtatcgtatc cctgtggcaa
      541 ctgttgaatg aaaaagtctg cattagctgc tttggcagca gcaattactt gctctcgact
      601 ggcttcagga ttgccaaagg caatattatc atgaatggtc ccttgtgtga gccaggtttc
      661 ttgaagcacc ataccaaact gctgtctcaa tgatactcgt gtataatcat aaatggattg
      721 cccatccagc aagatatctc ccgagctaat gggataaaaa cgcataagga gattgataag
      781 agttgatttt ccagcacctg tcggaccaac gatggctacc ttactaccag ctggaatatc
      841 gatagacaag tccttaatca aaattttttc aggatggtag ccaaaagaga catgtttaaa
      901 ggaaatagct cccttaactt ggtcactggt caagacttcc ttacctgttt cagctacttc
      961 agggctatct aagactccat agatacgctc tacgcaagcc agagcacttt gcaactcagc
     1021 tagcactgaa gaaatatcgt taaagggctt ggtgtattgc tgaacatagt tcaaaaaagt
     1081 cactaaacga ccgacggtca aggttgaacc catcatgata cgataagctc ctactccagc
     1141 taaaagggca taaatgagtg catttacaaa gcgagtcgaa ggattgaccg ttgaagaata
     1201 aaagatggct gactgagaat agcctgagta gttgtcatga gcctcacgca atctttggat
     1261 aaactctgtt tgagcattga aggactggat tatagtctgc tggctaagcg attcttcaat
     1321 caactgggtc tgaatccccc tcgtctctgt ttgcttctgg aagagatgat aggatctctt
     1381 ggcaataaag cgtgaaatca ccatggacag tggcgtcaac agcaagacta agagagtcat
     1441 gaggagatga atttggagca tggctagaat actaaccaaa atcatcaaaa caccaatgaa
     1501 aaattggtta aaaatcatgg tcaagccagc tgccaactgt tcgatatccg tggttacacg
     1561 actgaccatc tctccattgc cttgccgatc cgcaaaagca atcggtaacc gatggagttt
     1621 atggatgatt cgctctcgta aatctctggt ataagagaag attagacgat tatagaggag
     1681 aggattggcc cattgtacca gagtatttcc tattaccacc aagagcatct ggagaaaaat
     1741 ctgccaaaaa actggtgatg aaccagccac taggacttgg tcaatgacct gcccaatcag
     1801 aataggtagg taaattgata agccaacttg ggcaatagtt cctagaaagg ctaggaaaag
     1861 gaggaaggga tggtttgcta aatctacggc taaacgtttg agcgtctggt ttacagtttg
     1921 tcgtttcatt ctagtcctcc tttccatgtt gggatgcatt gatttcacga tagacttggc
     1981 tggatttcat caagtcatcg tgcttgccaa cagctagcaa ctcacctttt tccaagagga
     2041 gaatctggtc cgccatctgt aaagttgagg ttcgttgaga gatcaaaatt aagctcgtgt
     2101 ttggaaaatt ttctctaata gctttcaaga gcttggactc tgtaatggta tccagtgccg
     2161 aggttgcatc atctaggatg agaaacggag cttggcgcaa gactgctcgg gcgatagaca
     2221 acctttgttt ttgtccacct gagaaatttc gacctcctgc ttcaactaga gcatccaaga
     2281 gtccttcctt atcactgaca aaatccttag cttgagcaat ttccaaggct tgccagagtt
     2341 cttgatcagt cacttcttga tttaaaccta aagtcaagtt ggaacgaata gttcccttaa
     2401 agagttcgac cttttgaggt acataggcaa tccaagaccg ccactgctcc aaattaagag
     2461 gactacgtcc attttgataa aggtcaatgt tccccttgtc tactggataa agtccaagta
     2521 agagttgcac caagcttgat ttaccagaac cagttccccc gatgatacct agaatttgtc
     2581 cttgagtcat atcaaaggaa atgtatctca gagaaggctg ggccgcatca ggataggtaa
     2641 aggtcaattc ttggacttgt aaaaccttat ctctggtagc ttgcttttgt tctaactctg
     2701 aatggatatc ctctggagcc tcaacaaaga cttcctcgat tcgcttggct gagatatagg
     2761 actggttgag agaatttatc aacatggcta gcttgaccaa ttccaccaaa atctgtaaga
     2821 ggtaattgat aagagcaatg agagcacctt gactgagcac tcctccttga attgaaatat
     2881 agccttgcca gataataacg agaagagttc cattgacaat cagataggtc agaggtgtta
     2941 ataaactaga ccagaaacct gtcttttctt gtaatctagc ataaacttgg ttaagggttt
     3001 gaaaaatctg taactctcgt ttttcttgac caaaagcacg aataacccgc atcccttgca
     3061 attgctggcg cgtttcctga accagttggt ccgttttctt tctgagacta ctgtagagag
     3121 gattgaccaa tcgagataac cctacaatga caatggtcaa aatggcaacc atgactaaga
     3181 accagaaagt caactcagtt gagattcgat aagccataaa aatggcacca aaaacgataa
     3241 tgggcgctcg caaaaagaga cgcaggaatt gattgatacc agtctgaatc tggtaagtat
     3301 ccgaagtcaa gcgagtgacc aaactagatg ttgtcagacg gtctctgctg tccttgggca
     3361 aggaaagaat ataacgataa agatcgtttg tcaattcctt agcaaaacct actgctgcct
     3421 ttgctgagta aaattgagct atcaaggcca ctaaaacgcc aattactgca aagataagga
     3481 gcaggccaat ctgcatccag agatgacctt gatctccctg aggtaaagat tggtcaacaa
     3541 tcccagcaat caccatggga accaagagct caaaaacagc ttctaacagc ttgaacaagg
     3601 gggctaaaat tgattccttg atgtagggtt tgaagtaaga taataggtgt ttcataaatc
     3661 ccttctattc atattctaga aatgaagaaa gtgggaagcc ccactctctg ttttatttgt
     3721 ttaagtaagg caatagatag ccatatcctg ctttttccat ctcatccttg gccacaaagc
     3781 gtaaagaagc agaattgata cagtaacgga ggccgcctaa ctcccgcggt ccatctgtga
     3841 aaacatgacc caagtgagca ctgcctgaac gagaacgaac ttcaattcgc tccattccat
     3901 ggctcagatc cttgtaataa tgaatcaact ctttggaaat cggacggcta aaacttggcc
     3961 aaccacaacc tgaagcaaac ttatccttgg caaaaaagag tggctcacct gtcgtaatat
     4021 ctacataaat cccctcttca aaggtttggt cataggcatt ggtaaatgga gcctctgtag
     4081 cagcttcttg tgtgacacga taagactctt cagatagact ggccttcaac acctcttgac
     4141 taggcttttc atagtttgct gcatcaatca atggcttatc agcatcggtc acatcgatat
     4201 gacagtaacc tgaaggattc ttcctgagat aatcttggtg gtagtcttca gccagaatgt
     4261 agtggcgtaa ttgctccact tctactgcaa tctttcgacc cagcatgcgt tcctgctcct
     4321 gtaccactgt gtagatagct ggcaaatctg cttcatcctg ataataaatc ccagttcgat
     4381 attggcgacc acggtcattc ccttgttgat tgatagatag aggatcgata actcggaaat
     4441 aataaagtaa aatctctctg agtgacactt ccttctcatc gtaaatcact tggaccgttt
     4501 ctgcatggtc tgtttccttg atcaactggt aattggtcgt ttcgacttga ccattagcgt
     4561 agccaacact ggtttctagc actccagaaa tgcgtgaaaa atattcctct aggccccaaa
     4621 aacaaccacc tgctagataa atttctgcca tctttatttc tcctttatca cgtttttaac
     4681 taatactctt cgaaaatctc ttcaaaccac gtcagcgtca ccttaccgta tatatgttac
     4741 tgacttcgtc agttctatct gcaacctcaa aacagtgtct tgagctgact tcttcagttc
     4801 tatccacaac ctcaaaacac tgttttgagc agcctgcggc tagcttccta gtttgctctt
     4861 tgattttcat tgagtataaa cttcttttca caaaaaggat atgaaaccct ctggtcaaga
     4921 gtttccccat cctatcttct attctttatt ttgcttctac acggacacct tgggtatcaa
     4981 ctctcaagtc atgcagtttt cctttgaaag gttgcttttc caattctgcc ttaattgttg
     5041 gcatcttgtc atgagaagcc agaaccataa ctgtcggccc agcaccagaa aggtaggttg
     5101 cataggcccc attttctttg gtcacttgct taatcatcgc aaattctctt accaagtcct
     5161 gacgatagcg ctcatggaag agatctccct cgattgcttg cccagcggtc accatgtctc
     5221 ctgccaacaa ggcagcaacc gctacattgg cgatagaact tgcagcaaca gcttccttat
     5281 aagacaattt tttaggcaag acactacggc tgtcgcgagt acgtaattca tagtttggaa
     5341 tgtaagctag aaaatcacac tctggaaagt ctgctacgat agcagagact tgcccttcaa
     5401 cagaacttgc aataacgaga ttaccataaa tggctggagc cacattgtca ggatgccctt
     5461 caatcttggt cgctaactgc aatttttcat ggtctgataa gttgagttga cccagttggt
     5521 tggctagttc aatcccagca acgataaccg agctggaaga acccaaaccg cgcgccaaag
     5581 ggacatcact ggtcattttc aagcgtcttg gttgcaagtc tggtacaatt tgcaaagcga
     5641 ttttgagcaa gagattacgc tcatcatgtg gaatccattt gccaatctgg tgttcaatca
     5701 gccactcatc tcgttcttcg cagacctcaa tttgaagata cttggttaca gctacaccga
     5761 ccgagtcaaa acctggcccg atattggcac tggttgcagg tacaataatc ttcatcttat
     5821 tctcctagca ccttgaaggt attcaagagg tcgaattctg aaaccttctt caattcagct
     5881 gagacatttt caagctgggc tttattaatc ttgtgtgtga tgataacgac acgcgccttg
     5941 tcaccctctt tgccatcttg aaggatttgc ttaaaggaaa tatcttgagc attgaagatt
     6001 tcagccaact tcaagacctg accttttgag tctagagcca agattgagaa atagtagttt
     6061 gctttgacat cttcaggatt tgccaagacc aagtcacggc tatattcgtt gaagtctttg
     6121 ccaatagtac catcattcaa acgacgaacg atacggacaa tatcagctac aacacttgtt
     6181 gcagttggtt tttgacccgc acctggtccg tagtacatag actcaccaat accgatagat
     6241 tctacaaaga cagcgttcat tacgccattc acactagcaa gtgggtgcgc tttaggtagg
     6301 aaggttggag tcacttctgc agcaatacct gaagaagttt cctcaataga accaaccaat
     6361 ttcactacgt aaccaagctc ttgagctaca gctacgtctt ctggtgtgat attgcggatt
     6421 cccttgtggg ctacatcatc aaaggcaatc ttcatgccaa aggcaaattg gctcaaaata
     6481 accatcttgt aggctgcatc aatcccatct acgtcattcg tcggatcgct ttctgcaaat
     6541 cctagacgtt gtgcttccgc aagagcatca tcgtaagacc agccttcttc caccatcttg
     6601 gtcaccatga agttggaagt tccgttgact actccaagca cgcgcgtaat tttatcagaa
     6661 gccaaggaat ttgctaaagt acgaagaatt ggaatcccac cagcaactgc tgcttcgtag
     6721 taaagtgcta ccttgttagc ttgagcgatt tctagcaatt ctgcgccatg gacagctaaa
     6781 aggtccttgt tagcagtaac aacgtgtttt ccagcttcca aggcacaagt gataaaggtt
     6841 ttagcaggct caatacgccc catcaattcc actacgatag taatatcctg gtctgataaa
     6901 atatcatcca cattggttac aaagttaaag tcattccctg ctgcaagcaa gcgatttttt
     6961 tcatcttcat ccttgaccaa taccttagca actttgatat ctgaatgtgc tgattgattg
     7021 atttttcctc cattttcctt taggaggaaa ggcacaccac ttgcaacggt accaaatcct
     7081 agtaaagcaa ttttaactgt catctttatc tcctcgaaat tttctaatat agccattata
     7141 acagaatttt gtgaaaattc ctattatagt aaatcactat ttcagtataa aaagaaaaaa
     7201 cgaatcagac gattcgctct tcttaaaatc tgaaaatagc tttccagaaa ggattagccg
     7261 attttttgca gattgagcac tgcatcgtga ctcatcaaga cttgaccata ctcttgtaag
     7321 actgagcgac tgatatcact atcgtctgca aactcgcgca tacgggccaa cagccaagct
     7381 ggatatgggc ttggatgatt ttcaatatcc actaaaatgg tcaaataata gcgctcgttc
     7441 attttgtaga gttcagaagt ttccatttca aaagtcactg tcttggcaaa agctaccaag
     7501 tcagccaact tagcaaaaga aaggatgtag tagatgtaag gttctttctt actctcagct
     7561 tcttgttcag cctgctcttg ctcttcttcc ttggcttcaa cttgctcaag agattgaatg
     7621 gcttcgatat catccttggt tttgtctgcg atgctttttt ccagggtttt gataaattca
     7681 tctggagaca tttgagccaa ttcttccata tctggcaaat ccgataagtc ttcaaaatct
     7741 agattttggt caatctttga cttggtcaca aagacatcta ccttatcagg ttttggagtc
     7801 acacggaagc tcaacatgcc tgtatccaga aagctatcag gcatctctag ctcatccaag
     7861 atagcataaa agaactcttc tgttttttct tgaggaacga gaaagtcagc aatctccatt
     7921 ccacgatcca tcaaatcctc taaagacatc gtgattttta aagttgtatc actaatttgt
     7981 ttcattttca ttgctagtaa cctcatactt tcagttctat ctattatact agatttttac
     8041 gattttatca aaagaaggct cctctatacg gatagatttt ccctagggtc tttctatagg
     8101 agactccaag agaaaatttc tgcagacaga tagaaaaagc cttcaaaatc ggctaagagc
     8161 cgattttgaa gaccttatac atcagaatac ttataattta aaggttgcta caccgaggat
     8221 agaacgattt aagtttctga gaatttgaag actttgctca aatttcttat aacgagtcac
     8281 tccgtactct tcaacaagaa ggactgtatc tctttccaaa agagatgata catcctgcaa
     8341 atctacaaaa tgcattcctt ttaaagcttc ttgactctgt ttcaatttat ctaggatagc
     8401 tttatttgag ctaacgatgg tcaattcctg tccagtattt ttgtatgaca aaacatctgc
     8461 taggttagca attgttgtaa tctctgttac aaaatcaatt tgatactgag aaaaatcacc
     8521 tactctattg attgttggat taaagagata aactaacaca tttcccatca caaccaaaat
     8581 cacacaaacc actccaataa caactaaacg aagaatcaga tttttcacat ttaagccaag
     8641 cgctgtttca ccatttgcgt tcaattcttt agagttgatg gtttccagtt tttcaatttt
     8701 cacatttgca taagcatgtt taaatttctc aatcaaccca tcaatttttt tctctaacaa
     8761 gtcattggca tctttacttg atgtcaaaat tttcacacca acccctgcat cgtcaatcat
     8821 atagtagacg gtcaattttt tccaccaata gtcattcgtt gaatttttca aggttgtttc
     8881 cgtcgtgtct aattcactgg caattttttt caactcactg ggttctacat cattgaaaag
     8941 ataagctcca ttcaaattac catcaatcaa tttcccataa aaatcactat aaccaccaat
     9001 ttgatgattc aaaatcgttt tggccgaatc ttctggagga gtgattttat agataagata
     9061 agttgaataa cttgttgtat ctttgacagt gtttttattc ctaactgctt taattgtaaa
     9121 tggtacagca atgagagcaa ataaagcgat gagagctaaa atatttgctt ttcgtttttt
     9181 ataaagattt gcaaacaaat cagctactga ataatgttca aacatgattt tttctccttt
     9241 gtttagtaga tactagtttt cctttgtaag catttttgct acaaatataa tcacaagaac
     9301 aattccccag aattgcattg taaataaatt gaagaaactt tctgaaaagc tgcttcttgg
     9361 cataaagaat agattattca agatgagtag ggataaagca aataggattg tccttgagcg
     9421 ataggctact tgcagcatgg ctataaataa tacgccgagt aagaaactaa gcagaaagac
     9481 tccaatcata ccatagtcgg tatacaactc catgatataa ctacttccga taccatgccc
     9541 tttcaagtat tccttgttca agacaagata ggatagattg tgggcataac tattactatc
     9601 aatagctagt tccacactat tggttgtatg ttcaaaggct tttcctccga aaatggctcc
     9661 caaactcccc cttgcaaaat aatcaagaac aggaccaaaa gtaaaattac ggaaatctcg
     9721 gtaagggagg ctactgttaa atagaaaacc tcgagccaga acaccaaaac tagttccttg
     9781 tttatagata aagtcaagta agatatccca gaaacctgta tgggaaactt ggacattatc
     9841 ccgtacataa ttaagtactc ccatcgctaa catgagaata ggagaaccta caaaaatcgc
     9901 taacttttct ttaaacccaa tccattttcc tttttcagtt tgctcccgca taaagtaata
     9961 aacaaaagca aataaaatac ttaaaataaa gggatttcgt gtcccaattg ccaaatgaat
    10021 agtattagct gcaataaagg agacaagcac tgctgtggcc tgcaatttct ttggcttggt
    10081 tgccagatac atacacattg catagaccgt aaaggtagac aaaatgtagg taaaataagg
    10141 cagtttactt tcaaaatttg catagtaggc atagtaggaa gtctgcaaac gatacaagag
    10201 ccgttcaaat aaccgaatga aatagaaagg ataggttaga agaaaaactc ctagtgatac
    10261 aaagcgtaac cgcttgatat aaacctcttt tagagaattt cctatatttg ctacttttat
    10321 tttcttccta gctatgaagt aacgagccag aatgcctcct gtggtcaagc ccagaatcga
    10381 aaccatgaca actataaagg caaaacgata ggctattgga tgataggtat ccaaagcacc
    10441 atccctaaaa taatcaatgg tcggtcttga taccagaaat acaaaaatgg ttaaatagaa
    10501 aataaaatgg attaagtaat acttgatatc attccaacaa gcaatcaagc tactaaccaa
    10561 caagaacaat aaagtagaaa gtaagctaac attattatta ttaaacagat acacaattcc
    10621 acttactagc gtcaaggcat aactgactat ggtcaaacta aataataatc gtttcccatc
    10681 aatcacttgg tcacccccgt tctaatgtaa ttttttagat ttttcaatat ttttcagtaa
    10741 taagaatcga tataaggaaa tatttatgaa tagggccaaa gcactaattc ttctcccctt
    10801 acggaaaatt ggattcctag aaatagcaaa ggcatggcct tttaaaaaac gatgaatctg
    10861 agaataggct tcaaactgtt tatactgatc atctagcaac atcttatcca gaataaagaa
    10921 gtgggcatag gccaatctga aaaaagcgac ctctttcaag tcaggatagt ttttcacaac
    10981 ttcattataa aacttttggt agatatcaat ataggctaaa tccttctctg catagggttt
    11041 ggtcgtaata ctatcccctc tatggaaata gtaataatag ggtttagtat taaccacata
    11101 cttcttggcc aacttgatta aatcaaaatg gtaataggca tcttcgtaaa tcaacccctt
    11161 aggaaaggat aggtcagttg caatctgtct cttgattagc ttattgcaaa tcgtcccagg
    11221 tattttttca cctatgaggt attcctttag aaatgtttga gaatcacaga caaaatagtc
    11281 atcctgattg gctgactgtg ggctttcatc attagcatag acattcatga caccacagct
    11341 cgaaacatcc gcatcttctt gaactaattg ctcatataag ctctgaatca tttctggatg
    11401 gatataatca tctgagtcaa taaaaatcag ataatccccg tgagcctgct tcatcccatc
    11461 atttcgtgct tgcgacaatc cttcgttctt tttatgaagc actgacaccc tgtcatcttg
    11521 ttcagcgatt gaatcacaca agcgaccact ttcatctgtt gcaccatcat caacaagaat
    11581 aatttccaga ttttgatagg tctgcttctg aatggaagct atcgattttt ctaggtactg
    11641 cgccacatta tagactggca caatcacact aattaatgca gtttccatgc tactcctcta
    11701 atagtttttc tacttgttcg atttgttttg taattgtaaa ttgttgaatg aattggctag
    11761 cctcatcgac atcaaagttt gaggcagaag tcatgtaatt agtaatcgcc tgagctgcct
    11821 cttgattgct ctcaatgatt tgtccaaatc gtccttcttg ggataattcc tcagcccctc
    11881 caacgtccgt agagataaaa gggagtccca gactcaaggc ctccacatac actccaggaa
    11941 aaccttcttg tttagacata gacaaaagaa ctttcgtctg agatagatac tgataaggat
    12001 ttttttgata accaaggaaa tgtacatagt cctcaatccc atactctttg actcgttttt
    12061 tcagttcctc ttccatatca ccagccccga taaaatagag atgatagttt tttccctctt
    12121 ggtgtaataa tcgtatcact tccactacac ggtcagaacc cttattttcc tcaatccgtc
    12181 cgatagtaca gatactttga ggagcaatct cgatatcgat cttctcttga gatttttcta
    12241 gaatagtctg aaaatcatat ccattgtaga ttgtctgtaa tttagaagta taatctggat
    12301 aaacttcctt gatagaattg ctggtctttt ttgaaatccc tacaattgta ttcgcagcat
    12361 ccaactggct tctatgtgat tctcttttag agctatcctt aagaagttct tcaatacttc
    12421 catgaatcca agatatcttc ttgacttctc ttcttttaga gaacaacagt ggtggattca
    12481 taatggtaaa agaaacttca acatcataat catcttttac aagcaaacga cgagccagtc
    12541 ttggaaaata aattctcatt ctccacaaaa aagctcgtaa ccatctggtt tggcgataat
    12601 cttgaaggga ttttaaaatg cgtacatgct ttggaacaga ttcatatccc ttgtcaaagt
    12661 gctccatttc aagaatatca atatcatact tttctggatc cagatttgaa acaatggttg
    12721 atagaatctt ctctgcacca cctccaagag aaaaagacca cataaaaaat aagatttttt
    12781 tcttagccac catattctcc cttgtattct gtataagact tatccatatc agcgatgaca
    12841 gcatcatgat gcggtacctg cttgtctgct ggtggaggcg tcatataatc cccaaaagca
    12901 gttctgagat agacatcata gccgattgga ataggcatct ctgttccttc aaatggcaag
    12961 aaaagattgt cttcaaaaga tgtgattggg tacttgtttc tcatgtagcc aggacctgag
    13021 cataattctg taatgccatc acaatcagcc aaatcatact tagtcatttc tttctcagct
    13081 tttttccaga tgcgataaca gagagatttt ggagtcaaac ccagtaaaat gcgacttccc
    13141 catttcatga gagcaccatg cttttctgga atagtttgcg cacaaaagag tgaataaatc
    13201 aaggcccaac gaacctgttt tttccgctca gctggatttt tcggataata atccaaaggc
    13261 aaaacatcca aggccagacc atgtggcaaa tccaaatcct gctgataagg cttgatacag
    13321 gtggtttcct tgtcacgaat ggtaataaaa agattacgat caacaaaatc cttgtgactc
    13381 tttgacaaga aataacgttc atctgcataa cgaggccata attctgctaa tttctcataa
    13441 tctttacgag gcataaaaaa gtctaggtcg tcgtcccaag gaataaatcc cttgtttcga
    13501 agggcaccaa tagcgcctcc gccacagaga taacagagca aatcatgttc tttacaaaag
    13561 gccacaaaat attcagccat ctccagacta cgagcctgaa ttgcttttaa atcagtcata
    13621 ttgttcatta ttctttctat cgtatcgttt cattatacca caaacaaggg gtgaaaatct
    13681 attgcagact gtaaaaaatc aaagcctgac tgctatccaa atagctatca aactttgatt
    13741 tttctgtctt atactcttcg aaaatctctt caaaccacgt cagcttcacc ttgccgtagg
    13801 tataggtaac tgacttcgtc agtcttatct acaacctcaa aactgtgttt ttagcagcct
    13861 gcggctagct tcctagtttg cactttgatt ttcattgagt attatcttat ctcaagccca
    13921 tttgagcgag cttggtttga tatttgtttt gatcaaccag caagcccaag cctccataaa
    13981 catcataggc atctacccag tcacccagtt ctggaatcgt caatttttca ataccatttt
    14041 ttgctccatc caaaacagat aaaccgtttg ttaggaggaa agtatagggt acgttggttg
    14101 aggtcatagc aaaaaccttt ccaagagctt cagaaccagt gaaaagttta gtgggatctt
    14161 taatttgctc taaaattgct gttaaaactt gttgctgtct ttttgtacgg ccgtaatctg
    14221 cctcatcatc atcacggaaa cgagcataat tgagcagggt cgagccattc atctgctgtt
    14281 ttccgacttt aatggtttgg gttggagact cagtctcggt agcgtataaa tcatctccga
    14341 ctgtagcttc tgttagggga cgcccattca atgttgaaaa ttgagcatca atcgtcaccc
    14401 catcagggaa aagcgtgtca atcgctgtgg caaaggcctg gaaatcaacc aaggcgtagt
    14461 acttaatgtc caagtcaaaa ttatctttca agacttggcg aaccatttct gccccttttt
    14521 gcccctcttg ttctcctaac tcgtaggcta cgtttaactt gttatctgtc tgttttctac
    14581 cgttaatcac ttgactataa ccatctatat agaccaaatt atcacgcatg aaactgacta
    14641 gcttcatttt cttatctgag cccccgacat ttaataccat aatagagtca gttcgtgtct
    14701 caacactgtt ctggccgatt cgaccatcag tacccatgat taaaatatta actccatctc
    14761 tagtgtcctg accattaaag acttctactt gagctgcccg agcatcagca gttttctttg
    14821 cgctagcatc ttggtaacca cgcaaaaaca tgaataccat ggccaaagcc acacagacca
    14881 aaagtgaaaa aatcaccata aaaattcgtt taagacggag cttccgtctt ttcttttttg
    14941 gaggggaaga gagtgcttgt gatttggatt gtgagcgact ccggttcgca tagcttggta
    15001 agtcaacctg ctcttctctt tcttgttcca agctagagct actatttccc ctagcaagag
    15061 ttagcttttc ttgcaaatag gcaaactcat ttttttctct ctcattgaga tagtgaatat
    15121 tttttagcaa ataatcataa cgcaactgct catgatgact taagggattt tctttactca
    15181 tcttctctcc tttccatggt ctgatattgg ataaatagga taggcaccca gaattttata
    15241 ctggattcca atcgcttcta attctttttg ggcaaagtgg accaagtcct tatcggtata
    15301 atccacatcg ataatgaaaa agtattcacc cagtgctgtc ttgagtggac gactttcaat
    15361 ttttgtcaag tcaattcctc gccaagcaaa ggtcgacagg gccttataaa gtgcacctgg
    15421 aaggttgtca ggtaatgtca aggccaaact catcttttca gtttgtgctt gcaagggaat
    15481 actaggattt tcagctccta gaacccagaa acgtgtgaaa ttggcttcca tttcctgaat
    15541 atcctcggca atcagttcca atccatattc ttcagcagaa cttctaggtg caactgctgc
    15601 aaagggctgg tctggatgtt cggaaataaa acgggccgca taagctgtac tagctgttac
    15661 ctcgatttga gcctctggat attgttcatc gatgaatttc tttccttgag ccaaggcctg
    15721 tggatgtgaa aaaatctttt caatcttagt atggcctgga accaccatca actgctgatg
    15781 aataggctga acgatttctg ctactgcttg gatgtgagcc tgatgaaaaa gatagtccaa
    15841 ggtttcatga acactaccct caatagaatt ttcaactggc accacagaat agttcactaa
    15901 tccttgctca taagccttga tgacatctgt aatgttggca aaagcctgca attcctcatg
    15961 aggaaaagct gtctgcacaa cgtggtgtga aaatgatccc ttgggaccta gataagcaat
    16021 tttcatctta gttcctctat aatttcctct gggcttagct tggtcacatc caaaacccga
    16081 ctagccactt cctcatacca agcctgtctt tcttggaaaa tagctactag ttcttccttg
    16141 ctattattta gaaaaagcgg tcgctgattg tccttatcag ctgcgatacg ttggtagagg
    16201 gtttcaaaat ctgctctcag gtagatgtta tctgtattag tcttgagtaa gtcacgattt
    16261 ctctgagaaa taaccactcc tcctccagtt gacacgactt ggtctgtttg tagtaaatca
    16321 gctaggactt ctgattctac ctgacgaaag gctgtttctc ccttttcagc gaaaaaattc
    16381 gcaatggaca tacctaggcg attctcaatc agagcatcca tatcaaggta attagggtcc
    16441 aagcctcttg caatagtcga ttttccagcc cccataaacc ctaataacac cttagccatg
    16501 aatcaagctc tccaaatcat caaagaaact aggatagctg gtattgatgg cttctgcacg
    16561 gtcaagctcc acctctccat ctgcaaccaa gagggctgcg atagctgtca tcatgccgat
    16621 acggtggtca ccaaacgtat tgactctagc accgtgaaga gctgattttc ctttgataat
    16681 catcccatct gccgtaggag taatatctgc tcccatacta tttaaggcgt ctgccacaac
    16741 ctgaatacgg tctgtttcct tgaccttgag ctcctcagca tccttgataa ctgttacacc
    16801 ttgggcttgg gtcgcaagta gggcaataat gggcaattca tcaatcaatc gtggaatcaa
    16861 agcgccacca atttctgttc ctttcaagtc agaagactca acagtcaagg tagaagattt
    16921 agcgactgga tcgatttcag taacttctaa ttttccaccc atggcacgaa tgacatcaat
    16981 aataccagta cgcgtttcgt tgattcccac attctgcagc actagatgag aatttggatt
    17041 aatcaaacct gcgactaacc aaaaggctgc actggaaata tctcctggta cgaccacctt
    17101 ctgtcctgtc aatttttgtg gcccttggac tgtgattttc ttaccgtcca cacttaaatg
    17161 accaccaaat tgtttcaaca tatcttcagt atgattacgg gtgcactctt tttcgataat
    17221 aactgactcc cccttagctt gtaaggctgc aaacatcaag gctgacttga cttgggcaga
    17281 ggcaattggc aactcataat gaataggtct taggtttttc gtccctttta agcgaagggg
    17341 aggcaagtct cgttcagttt gccctgaaat gctgacgccc atttttttca gtggaagggt
    17401 cacacggtcc ataggacgtt tggaaagact atcatctcca aacatctcta cttcgaaatc
    17461 tgcaccagca aggacacctg aaatcaggcg aatcgaggtg ccagaatttc ccatattaag
    17521 ggcattttgt ggcgctttta agccagccat gcctacacct tgaatggtaa taaccccatc
    17581 tttatcctca atttcaacac caaggtcacg aaaaacctgc atggtcgaaa gaacgtcttc
    17641 acctcgcaga atatcataaa ccttggtctc accctcagcc aaacttccaa agataatgga
    17701 acggtggctg atagacttgt cacctgggac gcggatacta ccatgtaaat ggcgaatgtt
    17761 tgtttttagt ttcatactgg acctcatact tgcaatactt ttacctattt tatcataaaa
    17821 agccagaaat tccttaaaaa ttcctgactt taggatcgtt cttttcttat ttcagcaatt
    17881 ctgaaactgg ttcaaaaaca attttttcaa tgtcagaaag gtaaatggcc aattgttgtt
    17941 gcttggtaaa gaattctgac aagaggctat ttccttgaat ctgtttacca aagccttcca
    18001 tcttagcttg gaaggacgca tctggcattt gacctgtctg tgctagtttt tgaatttcct
    18061 cttgaaaggc aagatattct gtaaagattt tgcttgcctc agcatctgct gcaatcgcat
    18121 ctttagctgc tttaacagcc ttgtattctg gtaatccgcg tagaccgcga ctgagttcgt
    18181 ttgcactatc gtaaatattt gacatgttct tctccttatt tgatgacgac tgtatagtcg
    18241 gtattttctg ttatgagatg ctcagctctt tccaagtctt gagcattttt aaatgaaatt
    18301 tgtaggattc cgtgaatatc ctcacgattt tcctcgttga tgtggatgtt aaccaaggaa
    18361 gttccacgta gcagttccaa aatccgcagg atgacatctt cttcatcagg aacgtcaaca
    18421 tagaggtcgt aagagctatc cacaccacca cgcttatgga tttccatggt ctggcgttgt
    18481 tcacgcgctt ggttaaaaaa gttccaaatt tgctcttcat ctcccttact aatggcctga
    18541 ccaatcactt ccaaacgttc cttgaaatcc tcaattctat ccagaatggt ctcgctattg
    18601 gacaagagaa tggaggtcca cattcctggc tcgctttccg caattcgggt catatctcga
    18661 aaaccacctg ccgcaaagcg ccttgccatc tcatgctctt gagcatagac cgcagtctgc
    18721 tccatgagac tagaagccaa aatatgagga aaatggctaa tctgagaagt gacacgatca
    18781 tgctccttgg catcaatctc gataaaacga gcatgaagac ctgaaagcag atccttcatt
    18841 tccttaagcg tgtcctgact tgtcaggctt gaaggtgtaa agatataata ggcattttca
    18901 aaaagattga catctgccga agcagcccct gtcttgtgac taccagccat gggatgggcc
    18961 ccgacaaagc gaacagactt gccagccaaa tactgctccg ccgcatccac aatggttgac
    19021 ttggtcgaac cagcatctga aataataacg ccttctcgca aatccaaatt ggccaactcc
    19081 ttaatgaaag caatagtttg tttgattggc aagctgagga taatgacatc tgccaaagga
    19141 gcaaaactag caaaatcatc cgttgcacgg tcaatcatac cttctttcaa ggcgatatct
    19201 ctcgaagctt gactacgatt ataacctaaa atttcataat ctggatgatc gcgtttgata
    19261 ccaagtgcca tagaggctcc aatcaaccca agacctgcga tatagattgt ttttgccata
    19321 ggaactcctt aatagttctt tgtatagtct cggtgtttgg ctaccgcttc ttttagttcc
    19381 tcaagattat ctgatgagaa tttttcgagg atttcttgcg ccagaaccgt tgctacaact
    19441 gcttccatga ccattcctgc agctggaaga gcagtcggat cacttctctc cacggttgcc
    19501 ttgtaaggtt cgtgggtttc gatatccaca ctcataagag gtttataaag agtaggaatg
    19561 ggtttcatga ccccacgaac aacgatgggt tgcccattag tcataccacc ttcaaaacca
    19621 cctagattat tggtacggcg agtataaccg tcttctttag accagagaat ttcatccata
    19681 acttggctgc ctttacgata accagcctca aagccaagac caaattccac ccctttaaag
    19741 gcattgatag agacaacagc ttgagccaat cttgcatcca attttctatc ccattggaca
    19801 taggaaccaa gaccaactgg aactcctccg acgactgtct ccacaacccc accgatggta
    19861 tcaccatcac gtttgatttg gtcaatatag tccttgattt cctgttctcg ttcttggttg
    19921 acaatagaaa cttcagactg ggcagctctt tgcttaattt cagcgactgt cagattttca
    19981 ggaacatcta tttccttacc accaaagacc acgacatggt tggcaatctc catatccagc
    20041 tcagccaaga ggcgtttggc tactgcacca actgccaccc gcatggtggt ttcacgagct
    20101 gatgaacgct ccaaagaatt tcgcaaatca tcaaaacggt acttaatccc cccaaccaaa
    20161 tcggcatgac ctgggcgagg atgagtaatt ttccgcttgc ttttaaggcg gtcttcaatg
    20221 tcctccgcag acatgatgtc cagccatttc tggtggtcct tattgatgac atccatagta
    20281 ataggcgccc ctgtcgtctt cccgtggcga acacccgaag taaagacaac ctggtcactc
    20341 tcaatcttca tacgaccacc acgaccgtag ccaccctgac ggcgtctaag atcctcattg
    20401 atatcctcag ctgtcaatgg aagtccagct ggaattccct caataatagc tgttagacgg
    20461 gggccgtgtg attctcctgc agttaaatat ctcatacact ctccttattt taccaagtag
    20521 tctttcatct cttccagaga aactgggtga atggtcgctg aaccaagctc tggcaccaag
    20581 accaatttca aggtgttacc acgcgctttc ttgtcatgag taagagcctg ataaagcttg
    20641 tcaactttcc aattttcata gtcaacaggc aagccgaatt tctgacacat ctctgtgata
    20701 gattgggtaa tgccagctgg catgaggcct ttttcctcag caaccttgga aatctgtacc
    20761 attcccatgg caacagcctc tccatgcatg accttgccat aaccggcagt cgcttcgatg
    20821 gcatggccaa tagtgtggcc aaaattgagg taaagacgaa taccattgtc caactcatct
    20881 tcaaccacca tcttgcgctt cacctgacaa gaatgttcaa tcaaggtctc tgcatgttcc
    20941 aaaatactct caacagaacc attcagtccc gtcaagagag cccacagttc tggatcctca
    21001 atcaagccat acttgataac ttcacccatc ccttcaatca actctctttt tccgagggtt
    21061 tcaagaacaa gtggatcaat cagaacccca tctggttggg caaaggtccc caccatattt
    21121 ttagcaaatg gtgtgttaac gcctgtcttt ccaccgatag aagaatcaac ctgagctgtc
    21181 aaactagtcg gaatctgaac aaagtgaata ccccgcatat aggtagaggc tacaaagcca
    21241 gccaggtccc caacaacgcc accaccaaga gcaacgattc catcgctacg agtcagacct
    21301 tgcttgacta gaaattcata gactttctga acagtagtta aattctttct ttcttcacct
    21361 tctaagaaat caaaaacagc tacctgaaaa ccagcatctt ctaggctgag cttgaccttc
    21421 tctgcataga gagaggctac atggttatct gtcacaatga ctaccttttg cggttgccag
    21481 agttctcgca accactgacc agcctgggcc atacaacctt tttcaatctg aatatcataa
    21541 ggatgatgag gaatatcgat tctgattttc ataggagagt ctccctttct ttattggtat
    21601 ttttctgtta aagactgcca aatctcttct gtcggcattt ccttgcctgt ccacagttga
    21661 aaagcttctg cagcttgata gagcaacatt cccagaccat tgactgctgg attgccctga
    21721 cttctagccc atttcaaaaa cggtgtttca aagggttggt atatgatatc tgcaactaaa
    21781 agagtttctg gtaagactat gttttcagga acaggagagg attggccatc catgcccaca
    21841 ctggtggcat taactagcaa atccgactcg gcaatccttg cttgcagttc agaaacatat
    21901 tctaaagcac acaaatccac tttaaagcct gtctgctcct gtaacttgtc taggtaaggt
    21961 cttgtttttt ccatagaaac ggaacgaaca aagaccgaaa tctgactgac gccatccaaa
    22021 atagcctgtg ccaagattga tttagccgca ccacctgcac ccagcagggt catcttttta
    22081 cctgaaattg taaaagaagg caagcactta aaaaatccct tgccatctgt attatatcca
    22141 attaaattgc cattctcatt gacaaccgta ttaaccgcac caatcaagcg cgcttcatcg
    22201 ctcagcttat ccaaataagg aatcacctgc tccttatagg gcatggacag attgatgcca
    22261 aacatctggt agcgacgaat attggccact gtttctacca agtcactcgc ttcaatctcc
    22321 caagccacat aagcaccgtt ggtagctgtc gcctcaaagg ctctattgtg gatgaaggga
    22381 gaaatagaat gcttaatagg attggcaaca actgcagcta aacgtgtata gccatcaagc
    22441 ttcatccaaa atctccctga tttttttcat gctagctaga gaaatctgcc caggggcact
    22501 aacctcatcc agactggcaa aagaccaact cgaaccagtc acatccgcag tgatacgaga
    22561 gaccttgccc accttaccca tagaaatggt cacatattcc tgttcaggat tgagggtttt
    22621 aaagcctcgt gtatagttca tcaagtctaa gacatcctgc tccgtgtgag ccatcaccgc
    22681 aaccttaaca agttttggat ttaggatcgt caactctgac aagatttcca tcatgttctc
    22741 aggtgtttct tggaaattat ggtaactcaa aacaagattt gggaagtcca gcatttcctc
    22801 aaaaacatcc ttgtagctat agtactcaaa atcaatatag tctggttgat agaattgcgc
    22861 aacttccttg attagatgga tatactcttc tggagaaagg tcgatttctc caccttcgga
    22921 gcgagttcgt agcgtgaaaa ccaactcacg gcctgcgaat ttttcaaaaa tggctggagc
    22981 tacctgcaaa atcgcttctt taggcagata gtcggcacgc cattcaatga tgtcggcatc
    23041 caggtacctc gtggcatcca gagcctgagc ctcctctaaa cttcttggca ttactgaaac
    23101 gattaatttc atttactaac cttcatacta atcaccttga ggtaattact actttcatct
    23161 tttttattat aggcaaaatc tgctggaaga ccatatttgt ttaaaatctg gtaacttctt
    23221 cctgcaaaac ctttatcaat ttgttctgta aatttctgac gggaaacatt ggcagcattg
    23281 gtactggcaa tgataatccc tcccggattt aaaatctcaa gactctggga aatcaacttg
    23341 tgataatcct tggccacaga gaaagtttgt tttttattcc gagcaaagct aggcggatct
    23401 aggacaatca catcgtaggt caagtctttg cgtttggcat atttgaaata ctcaaagaca
    23461 tccatgacta taaaacgatg ctcgtctgtg ctgagcccat ttgcctgaaa atgcgcttga
    23521 gacaattctc gtgaacgttt ggctagatca acagaagttg tctggctagc tcctcccatg
    23581 gccgcagcta ctgaaaaagc cgctgtgtag gaaaacatat tgagcaagga tttacccata
    23641 gccaagccgt caactaaact accgcgaacc tcatgctggt ctaggaaaat tcctgtcatc
    23701 aagccatcat tcataaagac ttgatacagg acaccatttt ctaaaacagt gaaaaagtca
    23761 ggtgcttctt gaccataaac atgggcagat tcatagtcaa aacccttaaa gcggattttc
    23821 tcataagccc ctaaaacctc agggaaaacc tgtctaaagg cttctgatat agtctgacga
    23881 atctgataaa cataagagtt ataccaagaa aagacggcgt agtcgccata aaggtccact
    23941 gtcagacccc caaagccatc tccctcttga ttaaagagac gaaaggcagt tgtcaaatca
    24001 tcttgatagt aggcgtttct cttttctttg gcttttctaa acaacgtttc aaagaaagtt
    24061 tgattgaagg ccaccttgtc tttgctgaca aaccagccca agcccttgtt ttgctgagaa
    24121 aggtaggcag tcccaagaaa gtttccttcc tgaccctgca cctctacttc ctgatcctta
    24181 agattgacat tctcaagatc actggcttct agtaaaacta gccccttagc aagcttcttt
    24241 tcaacccttt tgctgactct tattctattc ataactacca ttatatcaaa cttttagaca
    24301 attctcaaaa aagaaactac ccttgctttt ttactcttct tttaaaaaat ggtatactag
    24361 acttcctgca aaactaggaa gtaaatgtgt aagaatcaca ataaaaaatg ctcttccgtc
    24421 ttggaggagc atttcttttt atcaacgaaa atcaaataac aaactatgaa actagcctca
    24481 ggttaactgt gagattatag gtagagaggt tgaatcagca atatgtgtct gtcaaattta
    24541 gtgacaaagg tagtagaaga aagatgaaga aataaatctg cttcaatagg tatctggaaa
    24601 atttgatttt atagagaagc cttttgttac aaactcaata tactatcaat aaataatatt
    24661 atagaagcaa caataattat aatttcacct atctgcatca ttctatttcg aattctaaat
    24721 atatgttcta tcaagaatac ttggaacaca cacattatag taattaacgt ttttgaaatt
    24781 gaaaaatatc caaataaata aactataaac aacaaaaata gaactatgtt atatttctta
    24841 ttcaaaacat tcctccctat atttttgatt accaatctta atcatttaca actacattct
    24901 aacaaactat aaaagcgttt gtcgaattga atttatcaag caagcgacca accagctcat
    24961 cttttttcta tttctgccaa tatgcgtgac aggtaataat gatagccaaa aatagcaaga
    25021 gcaagcagga ggataagagc tcctactccc aagctgatgg caaggatagt ggagagagac
    25081 tgaaccaaga atatgctccc aattacaagg gccatcagga ttgcactata aataaacaat
    25141 aaaactatgg cgactatgcc atttgaacga ttcaccaggt ccgtaatgct actccaattg
    25201 gttgacagat ttttaacgtc cttaaagtaa tggtggcaag aaaggatgac actggcaagg
    25261 atccatgcca caataaggta aatcatcgaa atgatgggca agcctagata tagagaaaga
    25321 ccaagcaaag tcagaactgg taaaaaggac tggacagcat atataatcca aaatttcact
    25381 ttcacataac gagcaaagtc aaagggtaaa ctcttaagaa aatcaacatt ttccctctcc
    25441 aaggacaagg caattgaatg caggctggtg atattgttat tgacaactgc tataaacact
    25501 cctacaaaaa acaagggtaa ccagtatgga ggatgaatgt ctggaactat ctgagaatct
    25561 cggattttgg aaatcagacc gatcatcatg agataaggaa agaaagcact tgtaaaaagc
    25621 actgtaacca cgccagtacc ctgtcccaag agggtgaggt ggtagcgtaa aaccatgcgg
    25681 aaaaatccct ttttagtggt tgaaattctc tccttgctgc gacgttcttt tttgaccttc
    25741 tcctcactat taagcaggat cacgtcataa aaacgaggaa ggaccttctt tttggtcaga
    25801 taaagcagga agagagttag tcctatccaa gcgagcagac ccaatatggc ttctgtcgaa
    25861 aaaggctcca ctgctatttt gtaaaagata tgaagaggat aaaggagaaa tggaatgtct
    25921 ctaactttgt caacaatact tccaaaagtc gactgaagaa agaagataaa tattaaaggt
    25981 atgagaactc ctatcccaat catcacattc gaaaaaatag actgatactt tctgaagacc
    26041 gtagtttgag ccaagaaatg tactgccact accatcacta aagtaacaga gacaaataat
    26101 aaggtcaagg acagtagcat caaaggcaaa cccaaccaca gagaaggtgc tagcctaatg
    26161 tagaggacca gaaaataagc taggattggt acaattccag ctagagctgg caagaggaca
    26221 gacagacctt tggccattat aatctctgat tctttaaagg catagggcct ataggaggcc
    26281 aggtccttac tctcataaaa gacattgtaa aatgcagtga aagaagttga aaaggccagc
    26341 accagtaaaa tagcaaccat cgagctaaaa taaataggta tttcctcaaa aggaaaatga
    26401 atggctatat tactaaaaca gatgagcatc aagagactgg aaaaaatgta agaacttagg
    26461 actctagcgg aaacatttac ttttttccca ggattcttag cctgcttctt tcgtagatta
    26521 gccagattag cttcttgaga tgaatagagg atattgatat caactaattt tttaatgacc
    26581 ttgagacgca tctgaaacct cctcttttct accagcaagg ctaaggtaga tactttccaa
    26641 agactggtct gggttgtctt ttctcaagtc ctctacctta ccacaataaa tcaaatgccc
    26701 ctttttcaaa atagcaatcc gatcacagac ttgctcagct acctctagca catgagttga
    26761 aaacaaaact gtcttacctt tttgcgcatg ctccttcatc atttgcttca aatcaaaggc
    26821 ggcctgggga tccaaaccag tcaagggttc gtccaaaacc caaatatcag gatcagacaa
    26881 gagtgccccg atgacaaaga ctttctgacg cattccatga gaaagagttt caataacctg
    26941 atagcgattt tcagcaaaat caaaaacgtt caatagccta gctagactag cctccaagtc
    27001 agatctactc agatcatagg atgaggcgat caattcccaa aattcattgg ccgttaagcg
    27061 taaaaataag tcaggcgagt ctgctacgta gccaatcttt cgtttaatag ccaagcgatt
    27121 ttccgataac tcctgaccgt ctaccaaaat acgaccactg ctgggtgaaa tgatactgac
    27181 tagggatttt atagtggtcg attttccagc cccattatgg ccaatcaagc ccataatctc
    27241 tccattttca atctgcaaat tgagattact caaggccttt ttatcaccat acaacttact
    27301 aacattttga aattcaatca tgggacaact cctatcttta tctgtattat atatcgctat
    27361 actagaactt tgatacaaaa aaatcaatac tttattttaa gtagttaaaa tagtttcctt
    27421 ctatcttacg caaacgtttg cgctaataga tactttatga tagaataaag aacaagattg
    27481 acaagtaaga ggaaacatta tgcaaaatca aacactcatg caatactttg aatggtatct
    27541 gccccacgac ggtcaacact ggacgcgtct ggctgaaaat gctccacacc tagctcatct
    27601 ggggatcagt cacgtctgga tgccaccagc cttcaaggca accaacgaaa aagatgtcgg
    27661 ctatggggtc tatgacttat ttgacttagg agagttcaac caaaaaggga ctgtccgcac
    27721 caagtatggt ttcaaagaag actatcttca agccattcaa gcccttaaag cgcagggaat
    27781 tcaacctatg gccgatgtgg ttctcaacca caaggctgct gctgatcaca gggaagcctt
    27841 tcaggttatt gaagtggatc ctgtagaccg tacagttgaa cttggagaac ccttcaccat
    27901 caatggctgg actagtttta ccttcgatgg tcgccaagat acctacaatg acttccactg
    27961 gcactggtac cacttcacag gtacagacta tgatgccaaa cgccgtaagt ctgggattta
    28021 tctgatccaa ggggacaaca agggctgggc taacgaggaa ttggtcgata acgaaaacgg
    28081 aaactacgac tacctcatgt atgccgacct agactttaaa catcctgaag tcatccaaaa
    28141 catctatgac tgggctgatt ggttcatgga aacgactggt gtagctggtt tccgtttgga
    28201 tgccgttaag catattgact ctttctttat gcgcaacttc atccgcgata tgaaggaaaa
    28261 atacggtgac gatttctatg tttttggtga attttggaac ccagacaagg aagccaatct
    28321 ggactatctc gaaaaaacgg aagaacactt tgaccttgtc gatgttcgtc tccatcagaa
    28381 tctctttgaa gccagtcaag ctggcgcaaa ctatgacctt cgtggcattt tcacagatag
    28441 cctggttgaa ctcaagcctg acaaggctgt gacttttgtc gacaaccacg atacccaacg
    28501 aggacaagcc cttgagtcta ccgttgaaga atggttcaag ccagcagcct atgccctcat
    28561 tttgttacgc caagacggcc ttccatgtgt cttttacgga gactactatg ggatttcagg
    28621 ccagtatgct caagaagatt tcaaagaaat ccttgaccgc ctcctagcca tccgaaaaga
    28681 tttggcctat ggagaacaaa atgactactt tgaccatgct aactgtatcg gttgggtacg
    28741 ttcaggtgct gaaaatcaat ccccaatcgc agtccttatc tcaaatgacc aagaaaacag
    28801 caagtcaatg tttgtcggtc aagaatggac taatcaaacc tttgtagatt tacttggtaa
    28861 ccaccaaggt caagttacaa ttgatgagga aggttatgga caattccctg tctcagctag
    28921 atccgtaagt gtctgggcag tcaataccat ctaatagctc ataataacca agctaggtcc
    28981 aagcggattt ggcttttttg tattcacaaa aagacctacc caaatggata gatctttact
    29041 tgattacaat ttacctgcta ctgcatccaa caattcttgg atcttaggtt ggttgcttcc
    29101 tcctgccatg gccatgtctg gtttaccacc accacgtcca tcgatgattg gtgctaattc
    29161 tttgacaagg tttcctgcat gaaggtcttt tgtcttgctt gctacaagga cattgacttt
    29221 gtcaccgata gcggcaacta ggacaagaag atcagagtag tctttttgtt tccagttatc
    29281 tgcaaaggta cgaagggcac ctgcatcgga tacagacact tgactagcaa tgtaacgatg
    29341 accgttgact tccttaacat ctttgaagat atcgcctgcg gctgcagctg cggctttttc
    29401 tttcaactca gcattttctt tttgaagttg acgaagttgt tcttgaagtc cttctacctt
    29461 gtgaggtact tccttgactt gaggtgcttt caaggttgct gcgacagctt taagagcatc
    29521 ctcttgttca cgataggctt caaaggcttc cttaccagtc actgccaaga tacggcgagt
    29581 tcctgaaccg attccttctt ctttgacaat tttgaagaga ccaatctcag aagtgttgcc
    29641 aacatgagta ccaccacaaa gttcaataga gtagtcacca atagtcacga cacgaacttc
    29701 cttgccgtat ttctcaccaa agagggccat cgctcccatt tctttagcag tgtcaatatc
    29761 cgtttcaact gtcttaactt caagagcttc ccagattttt tcgttgactt gctgttcaat
    29821 cgcacgcaat tcttcagcag ttacagcttg gaagtgggta aagtcaaagc gaaggaattc
    29881 aacttcgtta agagatcctg cctgtgttgc gtggtttcca aggatattgt gaagggcagc
    29941 gtgaagcaaa tgagtcgcag tgtggttttt catgacacgg tgacggcgat tgctatcaat
    30001 tgccaaggta tattcttggt tcaaggcaag cggtgcaagg acttcaactg tatgaagggc
    30061 ttgaccattt ggggctttct gaacattggt cacagtagcc acaaccttac ctgactcatc
    30121 caagatttgt ccgtggtcag cgacctgtcc acccatttca gcatagaatg gcgtttccgc
    30181 aaagataagt gaggtagttc cttctgatac agcttctact tctgcattgt cagcaacgat
    30241 agccaccaat ttagaagaca attggctagc attgtggttg aagacacttt ctacagtgat
    30301 gttttgaaga gtttcatttt gcatacccat tgagccaccc ttgacagctg acgcacgcgc
    30361 gcgttcttgt tgttctttca tggctgcttc aaaaccttca cggtctacag tcataccagc
    30421 ctcttcagca atttcttcag tcaattcaac tgggaatccg tatgtatcat agagtttaaa
    30481 gacatcttga ccagcaatga cagattgacc tttttctttc aagtctgcca caatgccttg
    30541 ggcaaagtgt tgacctgagt gaagggtacg ggcaaatgat tcttcttcgc tcttaacgat
    30601 tttctcaata aagtcacgtt tctcaagcac ttctgggtag tagctttcca tgatttttcc
    30661 aacagttgga acgagtttgt aaaggaaagg ctcgttgata cccaattttt gaccatgcat
    30721 agaagcacga cggagaagac gacgaagaac ataaccacga ccttcatttc ctggaagggc
    30781 accatcaccg atagcaaatg aaagagaacg aatgtggtct gcgataacct tgaagctcat
    30841 gttgtcgcca tcttggtcat aaaccttacc agacaatttc tcgacttcac ggataatcgg
    30901 catgaagagg tccgtttcaa agttggtctt agccccttgg ataacggcca ccaaacgctc
    30961 caaaccagcg cccgtatcaa tgttcttatg tggtaattcc ttgtattcgc tacgaggaac
    31021 agcagggtct gcgttaaatt gtgacaaaac gatgttccag atttcgatgt aacggtcgtt
    31081 ttcaatatct tctgcaagca ggcgaagacc gatattttct gggtcaaagg cttccccacg
    31141 gtcaaagaaa atctctgtat ctggtccaga aggtcccgca ccaatttccc agaagttgtc
    31201 ctcaattgga atcaagtgac ttggatccac tcccacttca atccagcggt tgtaagaatc
    31261 tttatcatct ggatagtaag tcatgtaaag tttctcagct gggaagtcaa accattcagg
    31321 gcttgtcaaa agctcataag cccaagtgat ggcttcatca cggaagtaat ccccgataga
    31381 gaagttcccc aacatttcaa acatggtatg gtgacgcgca gtcttcccta cgttttcgat
    31441 gtcgttggta cggatagcct tttgggcatt ggtaatacgt ggattttcag ggataatggt
    31501 cccgtcaaag tatttcttga gggttgctac cccagagttg atccacaaaa gagttgggtc
    31561 atttacagga accaaactta ctgatggttc tactgagtga cctttggtcg cccagaaatc
    31621 aagccacatt tggcgtactt gtgcactaga tagttgtttc atattgtctc cttatttact
    31681 tgtttaatgt gattggcttt ccagcatttc cacatagtca atcgcgacac agagggaaat
    31741 gactaggtct gcataagcgt cttcaagaac cgttacggta taggtagagg tcagatggaa
    31801 gagttccttc ttaatttccg caatcaactg atcgcgatca tccagcaatt tgaaattcaa
    31861 atcccagata ttgccctcga tacgaagacc tagattatca aactcatact tatctcgcca
    31921 gaaggtcaac ttcttacgaa tgacaaaact cgagccatcc cgaagctgaa tctcaaaacg
    31981 aggaagcaag gtcaagattt ctttactaat ctcactgact tgttcaccag ccgcatcata
    32041 gatggtaaag gttttaggaa tcttaaaaaa tgatccctcc acctgatagg caatttctcc
    32101 cctgtcatcc ttgatagcga agcgttcgcc tccaagacga aacttttgtt tgacaagaaa
    32161 tgttttcatc aacacctcca aaaatcaaaa gacaagctca tatcacgaag ggcgaaaaac
    32221 cgcggtacca ccttcattca atgaacttgt cattctcttg ttcttatgca attgtatgat
    32281 tgagtagcat gacttcctag cttagatggc tcgcagcacc gccatttctc tggactaaga
    32341 caagtgaaaa tcaattctca actttcttat tataacgttt ttttaagctt gcgtcaactg
    32401 gaaatgatct ccgttgaatt agaccaattc cctacatctc tgattacttt ttcaggatat
    32461 attttttctt actgccgttt ttctttttat cccaaatttt catattacta aacacagcta
    32521 ctagaatatt tccaaatata aaggtgccta tcacccaata tatggactca gttgttaggt
    32581 attgtcgatc caagccatcc tttaaatggg atagtataac agtttggtta acaatcataa
    32641 aggttggcca gaaacttttt ttgaaaaaag tagacatttt cattatttgt tgccgctttc
    32701 tgtaaggtta atactcaata aaaatcaaaa agcaaactag gaagctagcc tcaagctgta
    32761 cttgagtacg gcaaggcaac gctgacgtgg tttgaagaat ataggcttag tatactacta
    32821 ggcaagcaaa taagcaacta gaatagaaaa agatagggtt ctaaaaactg acttctattc
    32881 cttaaaaacg aaccagcttg actgattcgt cttcttacgt ttatctccta cttccgatac
    32941 attttaaact gtaggaagag gtcgctatat ttccctgtcc atttatggtc aaatttctca
    33001 taaacttcta ggtgtttcat ggtttcaaca tctggataga aggccttatc ttcctttgtt
    33061 tcctctggga gcaattcctt cgctggtagg tttggtgttg aatagccgac atactccgca
    33121 ttttggagag cgttttcagg tttcaacata aagttgataa aggcataggc tgagtcttgg
    33181 tttttaactg ttttgggaat gaccatattg tcaaaccaaa gattgctggc ctctgtcggt
    33241 accacataac gtagattttc atttttttct aacatttggc tggcttcacc agagaaggtc
    33301 acgccgattg caacattatt ctgaatcatg tagcccttca tctcgtccgc aacgatagcc
    33361 ttgatatttg gagtcagttt gtagagctta tccactgtct cttccaactg ctgcggatcc
    33421 ttggagttga ggctgtagcc gagggaattg agtcctagtc ccagcacctc acgcgcccca
    33481 tcaaaaagca tgatagaatt cttatactcc ggcttccaaa ggtcatccca atgctcaggc
    33541 gcttcatcta ccatggtttc gttgtagaca attcctaagg ttccccagaa gtaagggatg
    33601 gagaatttat tacctgggtc aaaggactgg ttgagaaact ctggtccgat attttcgatt
    33661 ccttcaattt ttgaataatc aagcggaacc aagaggtctt cgtccttcat cttgttaatc
    33721 atgtattcac ttggaatggc aatatcgtag gtcgttccac cctgctttat cttagtgtac
    33781 atggcttcgt tggagtcaaa agtctcgtac tgaacttgaa ttcctgtttc ttctgtaaac
    33841 tgagtcaaga gttcaggatc gatatagtct ccccagttat agataaccaa tttttgacta
    33901 tctcgactat tgattttact atctaaatga gtcgcaattc cccacaagac aaggataatc
    33961 gctgcaattc ctgctaaaaa tgaatagatt tttttcatgc ttgctcctcc ttctcacgag
    34021 agataaagta ataacctaca actaggataa tactaaagag aaagactaga gcagacaggg
    34081 cattgatttc taaggaaatc cccttgcgag cacgagagta aatctcgact gatagggttg
    34141 aaaagccatt tcctgttaca aagaaggtca cggcaaagtc atctaacgaa taggtgaagg
    34201 ccatgaaata accagtaatg atagacggag tcaggtaagg aagcatgatt tccttgaaca
    34261 tctgaaattg actagctccc aagtcatagg ccgcatgaat catgtcgcca ttcatttcct
    34321 tgagtcgagg caagaccatc aagaccacga taggaatgga gaaggccacg tgactagata
    34381 gaacggtcaa aaagccaagt gaaaacttga gttgggtaaa gagaatcaag aagctagcac
    34441 caatcataac gtcaggcgca accatgagga tattattgag tgatagaaag gcttcttggt
    34501 atttcttacg agactggtag atgtaaatgg caccaaaagt cccgataatg gtcgctatca
    34561 aggctgatag gaaggccaag aaaaatgtct gagccaaaat cagcatgagt ctcccatctc
    34621 caaacatggt ttcaaagtga gtccagctaa aacctgtaaa gctattcata tcatcaccag
    34681 cattaaaggc atagccaatc aagtaaaaga taggcaggta gaggaccaga aagaccagtc
    34741 ccagataaag gttggcaaat tttttcatcg ttctctcctt tccttagtca cccacatggt
    34801 gatgaacatg gtcaggatga gaatcacacc gatagttgaa cccataccat agttgtcatt
    34861 ggttagaaaa ttctgctcaa tagccgtccc caaggtgata acgcggttcc caccaatcaa
    34921 acgggtcagc atgaagagac tcaaacttgg gataaagacc gactgaaccc cacttcgcac
    34981 accgttcata gatagaggga agatgacatg acggaaggtc tcccacttag ttgcaccaag
    35041 gtcgtaacta gcattgatga gattattatc catatcgtct aagacattga aaatcggcaa
    35101 aatcataaag gggagctcga tgtagcttgc gacaaagata aatgagaaat cagtaaatag
    35161 caactgctgt gaaccaattc cgataaattc caagaattgg ttaatagagc cattctgacc
    35221 aaaaatcccg ataaaggcat aagccttaag aagaaggttg atccaagttg gcagaataat
    35281 cagcataatc cagagttgac ggtgtttgag acgggtcaaa aagagggccg tcggataact
    35341 gataagcagt gtcacaaagg tcacaatgcc tgcataaagc actgagttga aactcatttt
    35401 aagataggtc aagttttgtg acgcaaagta agatttgtaa ttttctaaac tgaactggcc
    35461 ttcgatgttg aaaaaggatt gaccgaaaat caagaccaag ggtgccaata caaagagggc
    35521 aatccaaagc atgtagggta ctacaaagag tttagagctt gttttcttca tctctttcct
    35581 cctcgattgc attgatcaaa cctgcttctt gctcttcgat ttctacgtac tcctcaatac
    35641 gagcatcgaa ctcttcttcg gtttcattga gacgcatgat gtggatgtct tctggttcaa
    35701 agtccagacc gatttcctca cccacgatgg ccttacgggt tgagtggatc atccattcat
    35761 ttccaagttc gtcataggcg ataatttcat aatgcacccc acggaagagc tgggtatcga
    35821 ccttaacttg aagcttgcct tcttcaggaa gggtaatgcg caagtcctct ggacgaataa
    35881 cgacctcaac aggttcattt ggcttcatcc caccatcaac cgcttcaaag cgtttgccgt
    35941 taaattcgac caagtagtcc tcaatcatgg tacctggcaa gatgtttgac tccccgataa
    36001 aggtggcaac aaagtggttg attggctcat cgtagatgtc cacaggggtt ccagactgga
    36061 caatctcgcc atcattcata acgaaaatcc agtcactcat ggcaagagct tcttcctgat
    36121 cgtgagtgac aaagacaaag gtaatgccca atcgttgttg cagttcacgc agttcgtact
    36181 gcatgtctgt tcttaatttc aagtccagcg ctgacaaggg ctcatccaac aaaaccacac
    36241 ggggttggtt gatgatagca cgggcgatag ccacacgctg acgttgtcct ccagaaagtt
    36301 tgcggatgga acgtttttca taaccttcca actgaaccat cttgagaact tccgctacac
    36361 gttgctcgat ttctttctta tcaatgttac gcaagcgaag tggaaaggca acattttcaa
    36421 acacattcat atgtgggaac aaggcatagg attggaagac agtatgtacg tcgcgcttgt
    36481 tggttggaat atcattgata cgaacaccgt ctagcatgat atctcctgtc gtcgcatcca
    36541 gtaaacctgc aataatgttt aggatagttg atttccccga accagatgca cctagaaggg
    36601 tgtagaattt cccttcttcc aactcaaagt tgatgtcttt gagaaccttg gtgttgctgt
    36661 cttcaaaaac tttagagacg tttttgaatt cgataattga ttttttcaat tggcataaat
    36721 tccttctttt tcatagatta accgatcggg gctctgtcag gtcgccacta cctcttgcag
    36781 ggagtaaaac cacctgcata catcttcgct accaataggc tttcaccccc ctttccatga
    36841 catagcagca gcttttcaaa tacagcttcc tacttgcttt cacccaagat ccggacttct
    36901 ctttcaagcg taatacctga gtgttccttg actttttcga taaccgattg gatcaagtcc
    36961 tcgtagtctt tggccgttcc atctgcgaca ttgatcataa atcctgcatg cttttctgac
    37021 acttctacgc caccgatacg atagcctttc aagccagctt ctgaaattaa ctgacctgca
    37081 aaatgcccga ctggacgctt aaagaccgag ccacaagatg ggtattccaa aggttgcttg
    37141 agttcacgta ggtgcgtcaa gcggtccatt tcctgcttga taacctgatg ggttcctggg
    37201 gctagggcaa atttaactga caagacaact gcaccagact cctgaatagc tgaatggcgg
    37261 taaccaaaag ccaagtcttt agcagacagg gtttcgattt ctccatcctt ggtcaagacc
    37321 ttacaagact gcaagatgtg agcaatctcg ccaccatagg cacccgcatt cataaagaca
    37381 gcaccgccaa cgcttcctgg aataccacaa gcaaactcaa agccagtcaa actatgacgg
    37441 agggcaatgc gagttgtttc aatcaagtta gccccagctt ctgcttcaat ggtatagcca
    37501 tcaacagaaa cgttattgag cttgtcacac aagatgacaa atccacgaat cccaccatca
    37561 cgaacgatga tattgcttgc attgccaaga accatccaag ggatattttc ttggttggca
    37621 aatttcacaa cgcgagccaa ctcaaaacga tttcgtggaa agaccaaata atcagcctct
    37681 ccacctactt ttgtataact atagctatgc aagggttcct taaaacggat atcaattcct
    37741 tctaagattt caagcatttt ttctcttaca gacatgtcac tcttcctttt acaaaattca
    37801 ttccattata ccatttttag agacatttga cgaccataaa aataccttgt ttggattttg
    37861 cataagaaaa agaggttccc ccctttttat gattttttac aaaagatttc cttggttcca
    37921 taggcaacca gaacgagctc cagtgctaga atcacttcaa ccaagactgg atttgtcaac
    37981 cagcctactt ggaaaagaga tggtgccaga tcaaagaagg catgcaagcc ataggctgct
    38041 aggagataaa tccatttctt ctggcgaaca gcttggtaaa cccaaactgt caaaagtaat
    38101 tggaaaccaa gcgccaagat tcgctcaaaa ccaagcaaat aaatctgcca gaccgaaagt
    38161 gactgaatgg tttttaacat attttcagac agtaattgca taacctgtgg attctgagtt
    38221 tgaactgccg aaagaacgat gtaaagattg agtaaactaa taaggcctag aaaaatcaac
    38281 tccaagccac catgccctag gccataggcc aaggcatctg ccttttccaa acttctcttt
    38341 ttctccaacc atttgaagaa aacaagacga gccgtttcct caaaaaatgc tgccatggct
    38401 aggccataga taatatagat aagcggatga tcttgcaaga gggcaatact accgtctttt
    38461 tgaggatgca aaatcaagat atgcaccagt ttttccaaaa tctgcgaaga gacaaagaaa
    38521 gcgactgcac ccaagcccaa gacagctaga ttaatctggt atttcttttt ggcaaaccaa
    38581 atgcttccta tcagaaaagc tagcaacagc aacatggtaa taatgatatg aatggtcatt
    38641 ttcttctcct attctgcctt ttcaatatct tttttcatct cgtcaacatt gaacttagca
    38701 aacaagtatt gacggtcttg gactgggaaa cgttggtcca actggtcaac tgctcccacc
    38761 tcgataatgc cttccttgat gacaaaatcc atgacatgtc caccgaaggt caaatcatct
    38821 gatatgaagt gcagatggta gcctgccaca ctgaccccat ggaaaatctc aggcgtccag
    38881 aaaccaacaa tagtccccgc aacattgtca cgactatatt ccggttgatg ggttgcgaca
    38941 tcagcaaact tggtatcggg tgttgactta ggaatcatac gcacatgcat atgtgaaaat
    39001 tccccccgaa tcttgataga gcggaaaaga ttttccccat cataataaga ctcaattcgt
    39061 tctttcaatt ccttgtctgt catctcaaag cgctggcgga aaatgacctc tgcctgatgc
    39121 ggtaccactg cagcgtaagg aataagggca tctggtgaca cttccccaat ttctggctgg
    39181 tctcctgacc ctttggcctg ataagccttg ccatccaaga caatcaattc cccatcaatg
    39241 gaatccaagg ttcccaaacc aaggtcacca tgttctagca attctcctac tgtcatagta
    39301 ccaccataaa ggccagccat caaggctcca agggtattgt attgaaataa tttcactggt
    39361 tcctgcacgt tcttatccat tcactttctt gtctgttatt ctataaatct tactcctaag
    39421 tataccacat ttgcccctag atgtgaacga gagaaacgct ctagacattg ccaagaagga
    39481 aaaaaaaagg tacaatgtaa caaaatcaag ggaggtctgg aatgaagaaa caaagcaagt
    39541 acaaagaggt cgtttcctat ctgaaaaatg gtatcgagtc tggacgattt ccgacgggta
    39601 gtcgcctgcc ttctatccgt caactgagcc ttgactttca ctgcagcaag gacaccattc
    39661 aacgagccct gctggaatta cggcacgaac aatacctcta tgccaagcct cagagtggct
    39721 actatgtatt agaacaaggg caacatcaag acctagaaat cgaggttacc gacgaacatg
    39781 ccagtgccta tgacgatttc cgactctgtg tcaatgaaac cttgattggc cgagaaaact
    39841 acctcttcaa ctactatgac aatcaagaag gattagaaga cctaagacag tccattcaca
    39901 aactcctctt tgagcaagct ctctactgca aggctaacca actagtactg acttctggaa
    39961 cccaacaagc cttatttatc ctctctcaaa tatcctttcc tagacaagcc aaggaaatct
    40021 tggtggaaca gccaacctac catcggatga atcgcctctt gattgcacag gggctggact
    40081 atcaaacgat tgaacgaggc attgatggga ttgacttgga ggagctggaa ggccacttca
    40141 aaacaggaaa aattaaattt ttctacacca ttcctagatt tcactatcct ctgggacatt
    40201 cctattctga gcaagacaaa cgatctattc ttaacttagc tgccaagtat gatgtctata
    40261 tcgtagagga cgattatctg ggtgatttgg actccaagaa gggccaaacc ttccactatc
    40321 ttgatacaga ggagcatgtc atttatatca agtccttctc gaccagcctt tttcctgccc
    40381 ttcgtattac agcactcatt cttccaaatg ctatcaaaga agcatttgtg gcctacaaaa
    40441 atatcctaga ctacgacagc aacctcatta tgcaaaaggc cctgtcactc tatattgaca
    40501 gtcaattgtt tgaaaaaaat cgtttggctc gcttgaccaa tcatgaatct taccaaaaac
    40561 aaatcgagga aaggataact aaaacacctt gtccccttcc tcattatccc ctacacgatg
    40621 gtttattgct agacctgaga cagtatccta aaatcgccag tctcaaacac agtcaaccgg
    40681 gcttggactt ctttgaagag gcctatttaa gtacctgtcc ttatcaattt gccaaggtgt
    40741 ccctagacaa tctggaaaat gttttaaact atttaaaagc agaattggaa tgacatccaa
    40801 ctctgctttt tcttattctt caacttcagt tagacttgct gctttttcaa gatagctttg
    40861 gtaaattcct tcatccttaa gtttttggat gaccttgtct accacttctt tcaaatcatc
    40921 actatttttt ctaagagcaa cggcattggc gtcgccgtcc ttcatcttca agctgacagt
    40981 tgcgacagct aagccagcgt ttttagcagc ataactaagt gcaacaggct catccatatg
    41041 aacagcatct acttttccag cctgcaattc attgactgct tcacccatat tagttaggga
    41101 agttaattga gcttttggca attgttcctt gaccattgat tctggaacag tccctttttg
    41161 ggctgcaata ttagcacttt ctaggctagt taaatccttg tatttttcca catcagcctt
    41221 acgaaccaag aaactaatct tgttttcata gtatgggatt gaaaaatcaa agacttcttt
    41281 tctctcgtca gtagcactaa ttcctgcaac tgctaggtca gccttaccag tttgaagact
    41341 ggtcaaaaca ttgtcaaaac tcatgcttga gatttccaac ttaaccccaa gttcatcagc
    41401 gatagcctga gccatgtcga tgtctgcacc gactacctgg ttctttccat caaccaatga
    41461 ttgaaattca aagggtgcat agtcaggact ggttgccaca actaatttcc ccttttgctt
    41521 aatggcctca acagctgact gagaaccatt agaacctgac tggcaagcta ctaagaagaa
    41581 acttgcaaga aaattacata aaacaaatat ccattttttt gatttcataa ataaacaacc
    41641 tctctgttaa ttttgtataa ttataacgat atccaagtta cttgtcaagt gttttttaaa
    41701 tttttatctc aaaaatattt tttcgttcaa aaaaaggagc catcagttga tttcaagctc
    41761 ctttttatac agaattaaac tattttatag ttcgacaatc ttacctgttt caaagtagac
    41821 aacccattca cagatatttt tagcatagtc accgatacgc tccaagtagg aaataacttg
    41881 gaaataatca cgacccgtaa caatggcttc tggatttttc ttaatctctt cagtcgcaag
    41941 gtcacggata gtttcaaaat agtggttaat ttgctcatcc atggaggcca cccggtatgc
    42001 gtcgtcaaca gaaccattaa gataaagatc aagtgctgct tccacaacgc ttttaacttc
    42061 acgtcccatt tttttaattt cttcctctac agctgggatg cgttcttccc ccttcatacg
    42121 gatggttgcc tgggcaatgg ctacagcgtg atcccccata cgctccacat ctgatacagc
    42181 cttaaggaca gtcaagactg tacgcaaatc ttgagagact ggttgttgga gtgcgatcat
    42241 ttcaaatgat ttcttttcca gtttcacttc gtattcattt acttctgcat catcttcgat
    42301 gacctctttt gccaggtcac ggtcatgcgt gacaaaagca cgtaccgtac gattgatttg
    42361 tgagagcact tcttgtccca tagcgtagaa ctggttatgt aatttctcta aatcttcttc
    42421 aaattgagat cgtaacatct ttcatctcct tatccaaatt ttcctgtaat atagtcttcc
    42481 gtttccttgt gttggggatc aaggaacatc tgcttggtat cattaaattc aatcaaatct
    42541 ccatctagga aaaatcctgt cttatcagag atacgtgaag cttgctgcat ggaacgggtt
    42601 accagaagca tggtgtactt gtcttttaga ccatacaagg tttcctcaat tttaccagct
    42661 gaaatcggat ccaaagccga agttggctca tccaagagga tgattttagg actagttgcc
    42721 aagacacggg ccacgcagac acgctgctgt tgaccacctg acaatccaat agctgaatca
    42781 tatagacgat ccttgacctc atcccagata gaggcacctt gcaaggcttt ttctacggct
    42841 tcatccagaa cctgcttatc cttaattcca ttgatacgaa gcccgtagac aacattctca
    42901 tagatagtca tagggaaagg attaggttgt tggaaaacca ttccgatttc cttacgtaat
    42961 tcaaccgtat ctgtacgcgg actgtagatg ttgtggccat tgtacaccac ggatccagtt
    43021 gtggtcacct ctggattgag atctcccatg cggttgagag acttgaggag ggttgacttc
    43081 cctgatccag atggaccaat caaggctgta atttccttag gttggaaaga tagggaaaca
    43141 ctattcaaag ccttcttttt attataataa acggacaggt ctgatacctg taaaatcgca
    43201 tctgtcatac ggtttccttt ctaaccaaag tgaccagata catagtcatt ggtggactgt
    43261 agcttggcat tttggaaaat agttgcagtc ttgtcatact caatcaaatc acccaagtaa
    43321 aagaagcctg tatagtcact tgcacgagca gcctgctgca tattatgcgt tacaatgatg
    43381 atggtaaagt ttttcttgag ctcaaacatg gtctcttcta gttgcatggt cgcaatcgga
    43441 tccaaggctg aggctggctc atccattaag aggatatctg gcttaacaga gatggcacga
    43501 gcgatacaga gacgttgttg ctgaccacct gataaggtca aggctgactt gtggagatcg
    43561 tctttaacct gatcccagag ggcagcctga cgaagggagg tttctacgat ttcatctagg
    43621 acttgcttat ccttaactcc agcacgttca tgcgcaaagg taatattacg gtaaattgac
    43681 ttagcaaatg gattggggcg ttgaaaaacc attccaatgt gtttacgcat ttcataaacg
    43741 ttgatttctg gacggttgac atcaattcca cgatagagaa tctgcccagt tactttagca
    43801 atatcaatgg tatcattcat gcgattgaga ctgcgtaagt aggtagattt ccccgatccc
    43861 gacggaccaa tcaaagctgt aattttattt ctttcaaatt gcatatcaat ccccttaatg
    43921 gattcatttt taccatagta aacatggaca tccttagtag aaagggctac tttttcttca
    43981 ggaaaggtaa ggatatgctt ctcatcccag ttatatgttg acatggcttc tcctttaggc
    44041 agcggttaat ttcttgtgta gatagcttcc gaacttacga gctccaaagt taaaaatcag
    44101 gataaagatc aggagcacag cggcagaacc tgctgataca atggttccat ctggaatagt
    44161 gccttcacta ttgactttcc agatatggac agccaaggtt tctgcttgac ggaagataga
    44221 gatggggcta gtcacactaa ggatattcca gttagaccag tcaagagctg gcgccgattg
    44281 ccctgctgta tagatcagag ctgcagcttc gccaaagata cgaccagatg ccaagacgac
    44341 acccgttaca atacctggaa gcgcttctgg aataacaaca tgaaccactg tctcccagcg
    44401 agaaatccca agagccagac cagcctcacg ttgggtatgg tgaacgtgtt tcaaactatc
    44461 ctctacatta cgcgtcatct gaggcaagtt aaagactgtc aaggccaagg cacctgaaat
    44521 gattgaaaat ccatactcaa actggactac aaagatcaag taaccaaaga gacccaccac
    44581 cactgatggt aaagaggaca agatttcaat acaagtccgc acaaagttgg taacaggacc
    44641 ttttttagca tattcagcca agtaaatccc agctcccata gaaagaggta cagaaataat
    44701 caaggtaatg accaatagga aaaaggaatt gtaaagctga atgccaatcc caccacctgc
    44761 ttgaaaagca gaagaccttc cagtcaagaa agaccaagag atatggggca agccccgaac
    44821 caagatatag agaatcaagg aagccaagat tgtcacaatg atgctagcaa tcgtatagag
    44881 gacagctgtt gcaagtttat ctaatttctt agcgcgcata atttttcttt cctctttctt
    44941 tcgtaatcaa tttaatcaca ctgttaaaaa ctaaactcat caagagcagt accaaggcca
    45001 gtgaccagag aacattatta tttacagttc ccatgacagt gttcccaatt cccatagtta
    45061 atatagaagt taaagttgca gctggtgtgg tcaaggaagt tgggataaca gctgagtttc
    45121 cgacaaccat ctggatagct aaagcctcac caaaggcacg cgccatccca aagaccactg
    45181 cagtgaaaat accagaacgg gccgccttca agatcacacg ccagatagtc tgccagcgag
    45241 tggctcccat agcgaaactg gcttcacgat aataacgagg aaccgcacgc aagctatccg
    45301 ttgtcataaa ggttacggtc ggcaaaatca tgacaaagag gacggaaatc cctgacaaaa
    45361 tcccaaaacc agtcccacca aagacactgc gaacaaaggg aacgacgact tgcaagccaa
    45421 taaatccata cactactgaa ggaatcccaa ccaggagttc aatagctggt tgcaaaatct
    45481 tcgccccttt tggtgatact tcggtcataa aaactgctgc accaatagca aagggtgttg
    45541 cgataagggc tgagagaatg gtaacgataa aggaacccaa aatcatagga agggcaccaa
    45601 attctttact agaaggattc caagttcctc ccaaaagaaa gtcaaagata ttcacaccat
    45661 tgacaaagaa ggtcgacaag cctttttgcg ctacgaaaac caaaatcatg gccacaagga
    45721 tgactatcaa agaaagacag gcaaaggtca aaccttttcc taatttctcc agacgagaat
    45781 tctttgatgg aagcaacatt ttcttagcta attcttcttg attcattatt gtctcccttc
    45841 caacactgtc acagttccgg cagcatcttt ttcaaccttc atttccttaa tcggaatata
    45901 cttcaatcct ttgacaatcc cttcttgggt ctcatccgag agaacaaaat tgagaaattc
    45961 tgcagccaac tcattgggct gccccaatgt atacatatgc tcataagacc acaagggcca
    46021 attattgcta cttatatttt ctggacttaa gtcatagcca ttcaacttca tgcttttgac
    46081 cgaatcatct atataggtaa gagataaata agagatagct cctggacttt ttgatacgat
    46141 tgattttacc gctccatttg aatcctgctc ctgactttgc atggcagact gaccttccat
    46201 aatgacagta tcaaaggtag cacgagaacc agagccggct gcccgattga taacagagat
    46261 gggtaagtcc ttaccaccaa gctctttcca attggttacc tcacctatga agatttgacg
    46321 aagttgctct gtcgttaggt tatcaacatc aacctcctta ttgacaatca gagccaagcc
    46381 agctaccgcg accttgtggt caacaagagc agaagcatca attccgtctt tttcctcagc
    46441 aaatacatct gagtttccta tatcaactgc cccagactga acctgggaca agcctgtacc
    46501 agaacctccc ccttggacat tgaccgtttt tccaacatgg atcgtgccaa attcatctgc
    46561 cgctacttca accaagggtt gcaaggcagt tgagccaaca gccgttatgg attctccacg
    46621 atcaatccag ctagcacagc ctactaaaca agccgtcagc caaaaagcga taagagacag
    46681 agcaagcttt tttctttttt tcactgtttt tctcctcgaa aataattatg aatactgtga
    46741 attttttaag tagttcttta tgagttgacg catgaattct taccaaattt ctgcgcaatt
    46801 gattatttat ataatatagg ctatattact ctttcctaac ctcctttttt catatgtgga
    46861 taaaatctct tgtctatccc ttcccccatt gtcacccatt atagtcattt cgtgtctctt
    46921 tttccccttt ttaatgcaag ggaaattact ctccttagat gataatccaa aagctagaaa
    46981 ggtatctcaa acctctctac tctcccagac tagtttacaa ctaaaaggaa aagattctat
    47041 tttatgagaa atctagttta caagcggtaa gaacgctaat aactaaactt cttgtactct
    47101 ttgaaaatct cttcaaacca gtgttttgag ctatctatgg ctagcttcct agtttgctct
    47161 ttgattttca ttgagtagta aaactacatg taatggcaat caagatatca agaatcatcc
    47221 tactaaaaaa atccatactt tcactataac atagaataag atatttgact agcattttca
    47281 tttgaatctg aggccttttg gaaaataatt tttcaaaaca tttccagtaa cctttgcaaa
    47341 gcccaagcca ttgcctttaa ccaaaacttg gtaccaacca tttggcagac tttctgccag
    47401 ctgaacgatt tctccagccg catacttgac aaacgcttct tggccaattt caaccgactg
    47461 ttcgacctga ctcggtttca aggctaaacc aagagcgaaa ctgggctcaa agcgtttctt
    47521 cttaaaagtg cccagatgca gtccattgcg agcaatcttg agcttcccta aatctggcaa
    47581 aagttctggc aagagataaa gctggtctcc aaaagtctgc aagatacccg gtagattgac
    47641 cttcaaatgg ttttgggcaa attcctgcca caaggcaact tgttcacggc tgaggttact
    47701 cttacttgcc ttaaatttag gagctggatt gttaccctta aactgtagat gggcaacaaa
    47761 ctgaccctct cccttaaact gatgaggata catccgagcc gtttctggca ggtcaatacc
    47821 agctaccatt ccattgatat gctctactgg caacaagtca aaatcatact cttccagcaa
    47881 ccaattgaca atctcttcgt tttcctcggg tgcccaggta caggtcgaat aaaccagatg
    47941 accaccttca gctaacatgg tcactgcatc ctccagaatt tctctttgca agctagcaca
    48001 ttgactcgga taatctaagc tccaatagtc catagcatca ggttgcttac gaaacattcc
    48061 ttcaccagag caaggggcat caagaacgat taagtcaaaa tagcctttaa agaccttgac
    48121 caagcggtcg gcagattcat tggtcaccac gacatttgtc gctccaaaac gctccatgtt
    48181 ttcaaccaaa atcttagccc gtttgcttga aatttcattg gaaacaagta gcccctcccc
    48241 tgctagatag gctgccagtt gagttgattt gccccccggt gcagcagcca agtccaagac
    48301 cttcatacca ggactgggtt gggctacttg agccaccatt tgagcagcag gttcttgcga
    48361 ataaactaaa cctgtagcat gctcaggcga tttccctgaa accttcccat agtggcccca
    48421 aggggtttga gtaatggcat cagaaaagga aagttgctct tcttttaagg gattgacccg
    48481 aaaggccgaa accgcttcct cctcaaaaga ggcaagaaaa tctcttgcct catctcctag
    48541 tatctcttta tatttttcaa caaatccttc tggaaattgc atttaagttc ttttcctttc
    48601 gtaaatatag gactgaattt cctcctgcat ctcaagaggc accatcatga ccggctgtct
    48661 ggtttgaaaa tcaggagctt caccaaaaag ggtcacaacc cgatagccca gactttcccc
    48721 taaaatacta gctgcggcat aatcccatgg ttgcagataa gtgagatagg tcaacaaacg
    48781 ccctgacaaa atcttggcaa aactaatggc cgcacttcca tagacacgaa caccaagaac
    48841 cgatcggctc aaatcagcca gcccccattc attggtttcc agcataccac tattccctgc
    48901 aatgagaaaa tctccaagtg gtttagtttt aaaaggagct agggacctat catttagaca
    48961 aactggaaat tccccaccac cgtggtaaca atcccctttg accacatcat aaatcagacc
    49021 aaactgtccc tgaccatttt caaaataagc catcataaca gcaaaatctt cctgctgggc
    49081 tacaaaatta ttggtaccat caatgggatc aatgacccaa accttgccct cttgaaccga
    49141 ggctcgcaga caaccttctt cagcacaaat cttatcctca ggataacggg acaaaatctc
    49201 accaaccaag agttcctgaa cttctttgtc cagtctggtc accaaatctg ttggagagga
    49261 cttggtttca acacgcaagt cttcctgcat atggtcaaga atgtactgac ctgctttctt
    49321 aacaagctct ttagcaaatt caaatttact ttccaagaga aatctttcct tccccttttt
    49381 ctttggcagc ctgaactgct cggtaaagtg aatagccact aaccgtttca aattctcgtc
    49441 ccaaacgttt ctcttcgctc ttgcttggca cgaccgcttt gaatccctta taggagtcca
    49501 gtaacttttt agcctctact ttgccttcat aggcagcttc aacatcatta aaaaaagaaa
    49561 gcactgaagc aagttcttca gtgctccacg acaaatctag tgggtaacta tactgtttgt
    49621 tcattaacta ataccagctc tcattcttgc ttcttttagt tcttgcttac gataactacg
    49681 agggagaaaa gcacgaatct catcttcatt aaaaccgatt tgcatacgct tggcatcaat
    49741 aataattgga cgacgcaaaa gactaggata ctgctcaatc aaatgaagca attccgatac
    49801 cgaaatactc tctacatcaa tattcaattt ttgaaaaatt tttgaacgag ttgaaatgat
    49861 gtcatcagta ccattttcgg tcaaggaaag gatgtgttgc aattcttttc ttgttaaagg
    49921 actggtcata atattgtgtt ccacaaaggg aaccttatgt ttttctaacc aggccttagc
    49981 cttacgacat gatgtacagc tcggtgatag aaatagtgta atcatgcttt tctcttctta
    50041 tctatacttt gctacttcta ttatacaaaa aaataaggcg cttgactagg gatttttaga
    50101 aaaaaagcct attttttcag gaaaaatagg ctgtttgcga acgattgaca caattggatt
    50161 tggttaattc actcttaacg atggttttaa acgatatata tatttatata tgtaaattaa
    50221 aaacatcttt cctttcactt cctacgactt ttcagacaca gatagccaaa gaagttttca
    50281 tagagggcaa aaaagaggag gaaggcatga agaaagaagg tctctggcaa aatcataata
    50341 acaggatcct tggctggatc aaaaagccag gtatcatctc ccacaaagag aatttgatgg
    50401 aaaagagtaa agaattggtc aaaaccaatc aaaactcccc caagtccaat cattacaggt
    50461 aaaactacta gagccaggag actttttcga taaagagaca aaaagtcctt tttcacaatc
    50521 ctattgacaa agacatagaa acttggcagt gtcactagag ctactagctg aaccaaatga
    50581 aagagattct tgaccactgc gaaatggtgc agaccagctg ctgacgaacg aaaatcaggc
    50641 atctgtaaga cctgactaaa aggattggtc agataattca tcaagatatg aaaattgtat
    50701 tgaatggttt ctggttttag atagactcga ttcgttaagt ttagccactg aatctccata
    50761 ggatagaaaa tccaagccag ataaatggtc agaaggatgg agagggagag gagaaagagc
    50821 atagagcccc aaaagatcaa tttagttttc atcaaaatcc cactccgcaa ggctagaaac
    50881 cacatgtgtc ggtgcgattg gcaggccagc tacttcttct gccttagtaa aacctgtcgt
    50941 caccaagagc gttggaatgc cattgtcaat cccagcccga atatcagtca aataattgtc
    51001 cccaaccatg attaactctt cacgttccaa acctaagtgc tcaaccgcct tgtccataat
    51061 gatggcattt ggttttccga tataaaccgg cttcactcgt gtcgctactt caagcagcgt
    51121 aatcagtgag ccagcacctg gcaaaagacc gcgttccgtc gggatgttga ggtcaggatt
    51181 ggttccgata aaatgggcac ccttttgaat agcaagagtt gctgtggcaa atttttcata
    51241 gtcgacttgc caatccagac caactaccac gtaggcaggt ttttccttgt cttccacata
    51301 accagccgcc ttgatggctt ccttgagtcc tgcttctccg acgacataga cggtcttttc
    51361 aagccccaaa tcattcatat agtcgatggt tgccaaagtc gctgtgtaga cagtcgatag
    51421 gggcgtatcg atattaaaat tctgagccaa catctcctta acactctctg gagtgcgggt
    51481 tgtattgttg gttacaaaga gatagggaat gtcccgcttt tgcaattcat gaacaaaagt
    51541 ctctccagca gggattcggt ctttcccctt ataaatggtt ccgtctaaat caattaaata
    51601 gcctttatat ttcatctatt tctccctaag ccttttttat ttcttgccaa gtaatgattg
    51661 cttgggcatt gataacccca tcacttgtaa tttcatgctt gctttccagt ccagtccgtt
    51721 caacagccga tgtaatcacc ccacctggtc gaacttcctt gacatacttg aggttgattt
    51781 tcttgggaat atagtgggtc aaaaaatccg ctcccatgac ctcaaaaatc cagtccaagt
    51841 atttactgtt attgacatga ccattcatat ccaagtcgta aaaacgaaca tggtaatcct
    51901 tgctgatcgg ttcttccaag gactcatact tcggtccacg gataagtttt ttatcaaaat
    51961 cagactggta aggagccaca atctcaggtt caacagcatg gacttttcga ctgtcgcggt
    52021 ccatgagaac aaaggtcgcc atcatatgga tgagctcctg ccccgcttca ttataaatag
    52081 taaagcgacg gtagcaaaaa agtcgattgt agctcaaggc ttccgtttcg atggtaattt
    52141 cttccgcaaa acgaggcaaa cgaaccacct caatatcata ttctgcgata atccagacca
    52201 gattatagtc ttccaaaatg gccttatcac taactcccag ttcaatcgac tgcatccctg
    52261 aaacttgcag tgacagcaaa atcacatctg gaagtttgat atgaccgttc atatcagcca
    52321 tatcaaaagg aattttcatt ttcatttgat aagttaagcc catgatccta ctccaaaata
    52381 aatcgttctg ctacagtatc tcccaaaaag agacctctct ttgtcatgcg aacgtggtca
    52441 ccctcaatct gcatgaggcc ttgttgaacc aaatctctga caatttctcc ataaagtcca
    52501 gcaaaagact gtccaaattt ttcctcaaat cgcgccatgg aaaccccgga tttcttgcgg
    52561 agtcccaaga acatttcttc ttccatttgc tccttttgac tcaggtgatc ttctgtaata
    52621 caagcattgc cttcctcaac cgcactgaga taatgacgaa tgggaccatg atttttatag
    52681 cgtactccat tgacataacc agatgcccct gcaccaatac catagtattc agcattgtcc
    52741 cagtacatga gattatgacg actttcaaag ccgggtttgg agaaattaga aatctcataa
    52801 tgctcaaaac ccgctcgctc cagctctgca atgatgtact caaacatctc cgcttctagt
    52861 tcctccttag gcagaggcaa tttcccacgt cgcatccggt tcataaagac cgtatggttt
    52921 tctaaaatca aactatacaa actcatgtgg ggaatatcca gtccaatggc tttagccaca
    52981 ttttccttta cttgctccat ggtctgacca ggcagagcat aaatcaaatc aatggagatg
    53041 ttgtcaaaac cagccagttt caggcgatcg atattttcat aaatatcctt ctccaaatga
    53101 ctgcgcccaa tctttttcaa catcttatca tcaaaggtct ggacacctag cgaaacacga
    53161 ttgacagccg aatttttcaa aacagctatc ttatccgcat ccaaatcgcc tggattggct
    53221 tcaatggtca actcttctaa gacagacaag tccaaatttt tagtcaagcc attcagtaaa
    53281 acctccagtt gcggagccga cagggctgtc ggtgttccgc caccgatata aagggttgac
    53341 aacttttcaa tatcataaga acgaaactct tccagcagat gctctaaata gctgtcgact
    53401 ggctgatttt tgatgaagac ctttgaaaaa tcacaataat aacaaatctg ggtacaaaat
    53461 gggatgtgca cataggctga cgttggtttt ttctgcatag taattattat accacaaaga
    53521 ctagattcca gataaaaatc accatcccca gatacatagt ccgtccggag atggtgatgg
    53581 tttattcttc tgttatatca atcacaatct cttctgagtc atcaagagct tcggcttttt
    53641 cttgccattg ttccttgaga ttatttaatt gattttttga tgcttctgtc gcttgaaaag
    53701 cataggattt agcttgagca agtatactgt ccacagtgat ttcacctgac tcaacctgtt
    53761 cttttgtttt cagaacaaaa tctgtagcct gctccttaac ttctgtcagt ttttcacaga
    53821 cttgctcctt ggcatactcc ggatcttctc tcaaatcatc tagaaaatct tgagcctgac
    53881 tgcaaacttg tttgccctta tcacttgtta aaaacaaggc aagagctgca cctgaaacgg
    53941 ttcctaaaag gattgaggat aatttaccca taaggattct ccttttttat tttttgaaaa
    54001 atttacttgc aagacgaaga gctgacagac ttgcaccagt cttgagtgtt tttgaaccag
    54061 ctgatgaagc tttcttgctc aagacacgcg catggtcatt gaggtctgaa acagatagag
    54121 ataaatctgc aacagcactg aagagtggat caatcgtagc caccttgaca ttgatatcat
    54181 ctgccaagac attgacctta gccaacaact cattggtgtg atgcaaggtc acatccacat
    54241 ctgaagtcaa ggttttaatc gtcttttctg tttcatcgat gacacgacca agcttttgta
    54301 cagtaatgat cagatagacc aaaaagacaa tcacagctag ggcaacaaga atatatgcaa
    54361 cttctaacat ttagttttcc tcctctgtaa tatagtaagg ggccttcttt cgattttgat
    54421 aaataacgat cattataccg agaccgataa agacaactga cagccattgg gacactcgaa
    54481 ggccgaagaa catgagacta tctgttcgca taccttcgat gaccatacga ccgaaaccat
    54541 accaaatcaa gtaaaaggcc gtgatatgac ctcgtctgag actcttccat ttccgtctaa
    54601 aaatcagaat caaggcaaag ccaagcagat tccatagaga ctcataaagg aaagtcggtt
    54661 gatggtagct cccctcaata tacatctggt cacggataaa gccaggtaga taatccagat
    54721 tatccactgt tgcaccataa gcttcttggt taaagaaatt accccaacgc cccaaacttt
    54781 gagcaatcat aacgctaggc gccgcaatat ctagaaaatc ccaagtattg atgagtttac
    54841 ggtcagcaaa gatatagagc acaagagccc cagttatcaa accaccgtaa atggccaaac
    54901 caccattcca aatggcaaaa atctctccta aattctgact atagtaatca aatcggaaaa
    54961 taacatagta gagacgagct cctaaaatag ccaagggaaa ggctactaag ataaaatcta
    55021 aaatatcgtc tggtatgatc ttctttctag gtgcttcttt catggtcaaa taaaccgcaa
    55081 gaatcaagcc tgtcacaata cataaggcat accaacgaat ggctaggggt cctagttgaa
    55141 tagcaattgg atcaagcatt ttgcacctca tttcgagcta tgagacttgt cagtcgttcg
    55201 tcgaacaaac gggtagcatc aaagcccatt tccttggcac gataattcat ggcagctgcc
    55261 tcaatcacaa cagagatatt acgacctgtt ttaactggaa tacgaatacg aggaatggct
    55321 acgccagaaa cttcaagttc ctctgcattg tttccaagac gatcaaaggt cttatgcgta
    55381 tcgtaatttt ccaaatagac agcaagctga acctgtgaag aatccttgac agcactcgca
    55441 ccgtagagac tcataacatc gataatacca accccacgaa tttcaatcaa gtgtttcaaa
    55501 atttcagctg gttcacccca gagagtaatc tcatccttgg caaagatatc gacacggtca
    55561 tcggctacca aacggtgacc acgtttgaca agctcaagac ctgtctcgct cttaccaatt
    55621 ccactatctc cctgaatcaa gacgcccatc ccataaatat ccatcaagac accgtgcaca
    55681 ctggtacgtt ctgccaaacg agaatccaga tagctagata actctccaga taaacgactg
    55741 gtagctgcac ggctggttaa aatagcaatc ttacattctc tagcagcctt taacatctcc
    55801 tctggaacca ccaaaccacg ggcaacaatg actgctggtg tctcaggtag aaacattttt
    55861 ttcaaaactt cataacggct gttggaaggc atgctgatca gataagacca ctccttcatc
    55921 cccaaaagtt gaatccgctc tggtgtatag tagtcaaaat agcctgtcat ttcaagacca
    55981 ggtcgcgtaa tatccgctgt attgatttcc ttttcaagca attctggttc accatagaca
    56041 atgtctagtc taagcttttc aatcacttct tttactaaaa ccgacatcat ttcctccttc
    56101 aaatgagttc ttctctctat tatatcaaat tgtaggagga agtttcagat ttttgcaggc
    56161 tttggagtat ttatttaaaa gaaaaaggac tagatttctc tagcctttca tttcaattag
    56221 aattttttac gtttacgagc tacttctgat ttacgtttac gttttacaga aggtttttca
    56281 tagaattcac gtttgcgtgt ttcttgaaga gtaccagctt tagtaaccgc acgtttgaaa
    56341 cggcgaagtg cgtcgtcaag agattcattc ttacgtacta ctgttttaga catttttttc
    56401 actcccttca agttcaatat ctatttcatt ctacacgtaa aaggaataat tgtcaagcaa
    56461 aaatgcggtt taattttgat ttttttcttc catttataca agagttgaaa gcgttcaata
    56521 gaacattgct tttttatttt tcgagtaagc taagcgcttc agcatctgcg atgatggtta
    56581 catcagggtg attttggagg ctacttgcag gtaggttctc agtcactggg ccagatactg
    56641 ttccggcaat ggcttctgct ttcgactcac cgtaagcaaa aagaataata gacttggcat
    56701 ccaaaatgtt tttaatcccc attgaaatag cttgggttgg gacgtcttca atcttggcaa
    56761 agaagcgtgc attagcttcg atagtagact ggtcaagttc tactagatgc gtttgactgt
    56821 caaatggagt accaggctca ttaaagccga tatgcccatt gcgaccgatt cccaagattt
    56881 ggaggtcaac tggatggtca gccaaaattt ggttgtagcg ttcaacttca gcttcagcat
    56941 tgtccttaac accacgaggc aagaaacttt ctttaaatgg tttttggttg aacaagtttt
    57001 cttgcatgaa gtaacgataa gactgtggat tgtccccatc aaggcccaca tactcatcaa
    57061 ggttgacact ggttagattt gaaaaatcaa ggtcactctc aacaatttcc ttgtaaaatt
    57121 caagtgggct acttcctgtc gcaagtccta gagtttgagc tccattagcc aatttttcct
    57181 tcaaaatctc aaaagcaact tttccacctt gaacttggtt ttcaacttta ataactttca
    57241 tcttttcatc ctccatttct gtctatattt attatatggt atagaccaat ttttgtcaag
    57301 tgaaaacgat ttaatttcta aaaaaagagc gtccaaactt gaaacgtgtt ataatggata
    57361 ggattagaac ttagaaagaa tgaacagata tatgaataca gctgattttg atttccactt
    57421 gccagaggaa ttgattgccc aaacgcccct tgaaaaacgt gatgcctcca aactcctcat
    57481 cgtcaaccgt gagacaggag aaatgcaaga taaacacttc cactctatta ttgatatgct
    57541 ggaacctggt gatgcccttg tcatgaacga cacccgagtt ctccctgccc gcctctatgg
    57601 tcaaaaagtg gagacaggag gtcatgtgga acttctcctc cttaagaaca ctagtggaga
    57661 cgagtgggaa gttctggcta aacctgccaa acgcctcaag gtcggtactc gtatcagttt
    57721 tggtgatggc cgcctcagcg ctgtcgttac agaagaattg acccacgggg gacgcattgt
    57781 ccgctttgaa taccaaggaa ttttcctaga agtcttggaa agtctgggag aaatgcctct
    57841 gccaccttat atccacgaaa aattagatga ccgtgaacgt tatcaaaccg tctacgccaa
    57901 ggaaagcggc tctgctgcag caccgactgc tggtcttcac ttcaccaaag aactgctggc
    57961 agaaatccaa gctaagggtg ttcatctagt ctatctgact ctccatgtcg gactcggaac
    58021 ctttagacct gtttctgtgg ataatctgga cgaacacgaa atgcactcag agttctatca
    58081 actttctgag gaagctgctg ccacccttcg ctctgtcaaa aaaaatggtg gtcgtgtcat
    58141 cgctgtcgga accacttcta tccgcacctt ggaaactatt ggttccaagt ttgatgggca
    58201 aatccaagca gattctggtt ggaccaatat ctttatcaaa cctgggtatg agtggaaggt
    58261 cgtggatgcc ttctcaacca acttccatct gccaaaatca actctggtca tgttggtttc
    58321 tgcctttgca ggccgtgaat tagtcttaga tgcctaccac catgccatcc aagaacacta
    58381 ccgcttcttc agttttggtg actccatgtt tatttattga gaaagaattt ctctaaatct
    58441 tctaatacca ataaatcgct aagatattat ttcaaagaac atctacaatt gaaactctag
    58501 ctagctgtag aagacgccta gtacattgaa attaaaatgc ttccccctag cttcgaaaat
    58561 attgccatag attgcgttga ctctccaaat tgattcatct atattttatt tcagcttcct
    58621 atattttctt cgctgtttgt aaatcaaaat gcaagacaca tgagtagcac catatttgtt
    58681 actcttatct gtcctctcaa gagactatta tgagttattt cagaatcatt cactactttg
    58741 accctgactc tccttagtct caaaatcaaa gacttatact cttcaaaaat ctcttcaaac
    58801 cgcgtcaacg tcaccttgga ttatatatgt gactgacttc gtcagttcta tctacaacct
    58861 caaagcagta ctttgagcaa cctgcgacta gttttctagt tttctagttt gctctttgat
    58921 tttcattgag tattaaacaa aaagtgaaca aatctgaatt ctaatgtaca gaagactagg
    58981 cttgttcact tttttatagt cgctataaga tgaccttatc tatagctttt tatatataat
    59041 tatatattca gacatactat tatcaatttt gtctcaggga ggaatctgtt aacgcaccca
    59101 ttcaccatta tcattgactc tatagccatc tatacttgta ttgaccgcta actcacccga
    59161 tgcatttaca taataccatt taccaccaac ttggaaccat tgattaactt tcatagaacc
    59221 gttgctgttg aggtagtacc atgaaccatt aacttgtacc caacctgttg ccatggaacc
    59281 atcagtatta taaaaatacc acataccatt ttcttgtttc cagcctgttg ttggagcaac
    59341 tgctttagct ggttctactg ctacatctgt tccttggtta gatgtaacag atacaggata
    59401 cgaaggaata gatgattgct caggaacaac aactttttca ggttctctcg tccctctcct
    59461 tatacgtctt tttaccatct ctttagtaat ttgacgagaa gtagtttctt caattgttcc
    59521 atcacgttca tctacagcat agattgtagt aagagtaatt ttaccaattt ctcctacttc
    59581 ttgaccttta tcaagagttg ggtcatcgag atattctgtt tcgattggaa tttcttggac
    59641 aagaacttgg ggcttggttc cttttttaac aactcttgtt tgagagtctt ttttttgact
    59701 taaagtactc tcagttactt gtccactctt tccatctaca ttataagtta tcgttgtaac
    59761 tgttttccca ttctttccta gagtaatctc ttgctcctgt cctgcagaaa ggtcattgtc
    59821 tgcttcatat ttagtagcaa atggaacaag aacttcttca accttgcttt tagctggaac
    59881 tttgataact gtatccgtgg cttcttttct atcaacagta acctgttcgg taacataacc
    59941 agtctctgga ttaacatcgt aggtccttgt cgtagttaca tagccatcct ctccatcaat
    60001 tgtaacagga ttttcactac ggtcttttgt ttcatctttt tcataacgaa ttcgcgtact
    60061 tgaaattttc ttggttacta ccttaggttt agtcgctact tttacaataa tatccccatt
    60121 gtcaacgtca tcatactcta ttccctcttc tttatctcta gtatcatctc tgacatattg
    60181 aatcccatca gcagcatgaa caaaacttgt attcagattc ctcctaaaaa taaagttagc
    60241 ccgattaccg cagaaccaaa aatctttccg agtttacgta ttgcatagcg cttattagta
    60301 ttagattttg ccattacatc ctacttctag tatagcatct tttctatcaa acattaaaca
    60361 atatacttta tatataaaat agacttagaa tgatatattg attattgaac taacacttta
    60421 actatatcgt aatcaatctc atatataaag gattgcagac atcttatcta aatacatgct
    60481 aatatattta gatacaaaca ttccaacttg ataactttca ctcatctttc atcattcctt
    60541 atacaactat gcagtataaa tagaatagtt ttctcatcag aatgagacta ttttaatatt
    60601 agatattttg atagaaaaaa cataaataaa attggttgaa tttaattccc taactcgata
    60661 gaggattcta ttttaaattt aacaacagct aggattacac tataaaaagc acattaccac
    60721 ctgttcggct ggagaatcta gtcgattagc tccctcttag ttacaagctt caagcgattt
    60781 tttaactaat actaaaccag attaaagaag gaactagaac atctgtcttg tactaatcaa
    60841 tatgctattt taaagtttca aataaacttg gaatgctaat tattatattt acaataaata
    60901 gttgacttcg atagaaacag aaaatagaat tcaacattct tccctactta taccataata
    60961 aataagatcc gcaagatagc cttttctctc tacaccatta acaatggttt gtagatagga
    61021 cattccagcc ttttccatga cacgacctga agctgggttg agactggcat aacgtgctct
    61081 gaccttttga aaacctgctt gagtaaaaca aaagtccaag atagctttca aagtctctgt
    61141 catcatacca tttccccagt aagccttgcc taacacatag ccaatttcac agcttaaatc
    61201 agcctcgtct atcttaacaa tgctgatatc tcctatcact tgctctgggt tttcttttag
    61261 acaaatggcc catttataat agttgagatt agtataggaa gcaacccaat tgcaaatcga
    61321 gtttcgagtg atttcgacat caggatgggg atcccaggta acataggtca gattctcagc
    61381 ggatgaagcc caattttgaa acatggcttc tgcatcactc tccacaaatc ttcttaaaat
    61441 caaacgttct gtctgtaata tttgcgtacc gatagatttc atgatgctac ctcacttcct
    61501 tatttctata ctcgtagtaa aaaggctcaa ctcagtaaca gctagaaaac gagtttgtct
    61561 tctaatttct tgacgcagtt gctgcctggt ttgaaatgcg ctctagcaag ctttttcaaa
    61621 cctagtcatc gttgcagggg taagacgatg aaatcgaact cttcgagtta ctgaatctgc
    61681 ctcattttct tatttctaaa ctcggggttc aagatccccc agaccttctc tcactttctt
    61741 atttcaagat gagaggctga aaacctccag tggaggtttt tcttgctttt taatttcagg
    61801 gcaagaagct aaaaagtccc ccggaccttc ttcgctttct catttctagg ctcagggtaa
    61861 aaacctccaa tggaggtttt tactcccaaa agtcatcaaa tacagtgatg ggtaagtggc
    61921 gtttgtgttg gcctttgtgc caccagtttt caatggtcgc ttgagcttct gggctgattg
    61981 ttttgccttc taggtagtcg tcaatctctg cgtaggtgac tccaagtgcg acttcgtcag
    62041 ctaggcctgg tttatcttct tctaggtctg ccgttgggat tttttcataa agggctggct
    62101 ctgcgccaag tttctgcaag agctgttttc cttggcgttt attgaggcgg taaagaggga
    62161 gaatatccgc accgccgtca ccaaacttgg taaagaaacc tgtgatattt tccgcggcgt
    62221 ggtctgttcc aatgaccgct ccgctatggg aaccagcaag ggcatactga gcaatcatac
    62281 ggcaacgtgc cttgatattc cccttgttga agtctgaaac aggactacct gtcgcttcaa
    62341 ctgcagctgt catggcatca gctgattcct tgatattcac aaccaagctg acatctggct
    62401 ggatgaaggc tagagctttt tgagcatctg cttcatcagc ttgcactccg tatggcaggc
    62461 ggacagcgat aaatttgtag ctgtcgtctc ccgtttcagc tcgcagttct tccatagcta
    62521 attgcgccaa acgccctgcc aaggttgagt cttgtccccc agaaatccct agtacaaagg
    62581 tttttaggaa gggatgtttt ttcagatatc tttttaagaa atcaatagaa cgacggattt
    62641 cttcctgggc atcaatcact ggtttgacac ccagctcttg gataatcgtt tcttgcaaac
    62701 tcattcttct tctccttcac caagggcttc cttgcgcatc ttatcaatca agtccatctt
    62761 atcttgccat acatcacgag ccaaatccac tggatagtgc tgcggattga gcacacgctt
    62821 atactcatcc cacaacttgt caaattcctt acgggcataa tcctgaatgt cagtcaaact
    62881 aggcaagttg taaattaata ttccttcttt gaagatatcc accaagagag gaacggcatc
    62941 aaaattacga accgtcttct tgatgtatgt ataggtcgga tggaacatct tgatttctgt
    63001 catgtcgcta atatccacac catcataagt gatatagtcg ccttctgact tgcctttttc
    63061 acgactggta atgcgccaca cctgcttctt acctggcgtc gacacttttt ccgcattatt
    63121 agacagctta atcgtattgt gcatctgacc agtttcatct tcaattgcaa caatcttgta
    63181 aaccgcccca agagccggct ggtcataggc tgtaatcagc ttggtaccca caccccagac
    63241 atcaatcttg gccttttgca tcttgaggtt aaggatggta ttttcatcta gatcattaga
    63301 agcataaatc ttagcctctg taaatccagc ctcgtccagt tgctgacgga ctttcttaga
    63361 aatgtaggca atatccccag agtcaatccg cacacccata aagttaatct gatcacccag
    63421 ctcacgcgcc acctgaatgg cagctggtac accgatgcga agggtatcat aggtatccac
    63481 aagaaagaca caatttttgt gggtcgcagc gtaagccttg aaagcctcat agtcattgcc
    63541 ataaacctgt accaaggcat gggcatgggt tcccaaaaca ggaatgtcaa agagcttacc
    63601 cgcacgcacg ttgctggttc cattggcgcc accaatcacc gctgcgcgtg ttccccagat
    63661 ggccgcatcc atttcttgag cccgacgtgt cccaaactcc atcaagggtt catcttcgat
    63721 aaccgaacga atacgagctg ccttcgtcgc caccaaggtc tggtagttga cgatgttcaa
    63781 aagagccgtt tcgaccaact gacattgggc tagaggtcct tccacctgca caatcggttc
    63841 attagcaaaa accaaatccc cttcttgggc agaacgaacg gtcaactcca acttgaaatt
    63901 gcgaaggtaa tccaagaacg ccccatgata accaagcgac tccaaatagg ctatatcact
    63961 atctgaaaaa cgcaagtctt caagatagtt cacaattctt tccaaacctg caaaaaccgc
    64021 atagccgttc ttaaaaggct gttggcggaa atacacctca aagaccgcct tcttattgtg
    64081 aatcccttgg tcaaagtaaa cctgcatcat gttgatctgg tacaagtccg tgtgcaatgt
    64141 caaactatca tctggataca tacttttcct acttccttag ctagaaaccc atgaaaattt
    64201 tcaagaactt tcatgtattc caataaatta gtactattat atcacatttt agctggattg
    64261 agaaaagagt aacaagctat tctccactct ccaattcatc catatcttgt tcaaattttt
    64321 tctgagccca ttcgccatag ctcttaagac caagattgcc aataaagatc cacggaaggt
    64381 aaatgatata agtaatgacc caagcagaca ggtatttaaa attcaaagga ttgtgctgat
    64441 aaatttctat gttgaattga taattctgca acatcaaaag agccgtaata gccaaggtta
    64501 ggaaaaaaca acccaaaatc gtaaaatgaa aacgactata gtaggtcact cccagataac
    64561 gggcacgatt gaaaaagtaa aatgtcccta tgatgataac gattagcagc atattagaat
    64621 taaaaaggct tggtgctaat actgaaatga tataagatag gagcgacaaa gcgatgcaga
    64681 tatagaaact ttcagagccc gctttattga acagttgttc ttctctttcg tctagtaatt
    64741 gataataata aaatctattt ttcatcttct tcctcccaaa atagtttgtc tagggttttc
    64801 cctaaacatc tgcaaatgga ctggcagagc gagagactgg gattgtattt ccccgcctct
    64861 atcaaaccaa tagtctggcg cgtcaccccg acagcatctg ctagttgacc ttgagttaaa
    64921 tcaagctcta cccgagctaa ttttaatttt aaatttttaa ccaccttcgt cctccttata
    64981 attttaatat tcatctactc ttaaaaaatt ccaaactaac acaagctgtc agctatttat
    65041 tataacccca ttaatttgca ctccagtatt atcttcagcc gaaaatcagt attttaggtt
    65101 gtttgaaata aacttcctag tttactcttt tatttttatt tagtattagc tttagtagga
    65161 gcttttaaac gagtttttat tgcttatatt tcttgtttag tttagttggt ttcatatcac
    65221 tattatataa tgcttttgaa aatgagccta gtataagtca aaaacgtgtt gaatagtgaa
    65281 agcaggagca taccaagatg actgattttt ttactgtatt ttaggtatgc aaaataatac
    65341 taaatgaaac taaaatgaat acttcttgct tttcttgaga gtgaaaaagt acaataaaat
    65401 gattgtagtg attagcacaa gatactgact aatagacatc gtatttgaag tcacaaatac
    65461 aggtaaagaa taaaaaggaa gaagttcaat tgctttgata aacaaatcat tactagtatt
    65521 catcatcatc gtatttaata tattagggat aaagagtagt aaagctacta aaataccaaa
    65581 taccaagcca cttttcaatt tgtataaata gaaaatgtaa gataatagaa aataaaacag
    65641 gactaacaaa attgtattga ctacaatagc tactataaaa tctaatccta aatcacctgg
    65701 aatacccaat ttacttacta tgactagtaa cacaatgcca ttcaaagcat aaataatgga
    65761 aactgagatg gcatatagaa aattagacaa gacgtaaatc atccgattct tctgttgatt
    65821 ataaaacaaa cttaccgtat tgtgggaaaa atctctacta atgactcgat tagcatgtat
    65881 aacagccatt aacataccga gcatagcata aaagtttgaa atatgcttaa taccaagcga
    65941 tgtcccttga gtctttagaa taaagaatgt aaccaatatc ggcggtataa acgagataag
    66001 caaaccgaga tatattacgc ctgatgaata taaatttctt atattttcct taagaaaatt
    66061 caatttattt aatttcatga ttataacctt cctttatttt gaacgattta ggtaaatatc
    66121 tttaagcgtc tcttttttag tttcaaaatc aactacttta atagagtttt cgttaaaaaa
    66181 tttaaaaagc tcactacttt gaatattccc agacatagta attctcaatc cctcttcctg
    66241 aacaatatcc ccaaattctt gtttggtaat gaaaatgtct ctatctgtag ctgatgaaaa
    66301 agctatctca aacaagaaat tatgactatc ttttcctact ttttgaaatg tcaaaagccc
    66361 gttctccaag aaaagaactc tctcacaaat ttcttcaatg tcttctaatt tatgactcga
    66421 tattaaaatt cccacatttt catgtaaagc taaatttttt agaaccgcta aaactatttg
    66481 tgatgattca atatctaaac cattagtcgg ttcatctaaa atcaatatat caggttccgt
    66541 aacgagagtt agaagcaaag ctaatttttg ttttgtaccc aaagaatagg tctttacttt
    66601 tttattaata gactgagtca aatctaactc ttggatcaaa cttctaaata tttcttgatt
    66661 gtagtcaaca ccatataaat ttgacaaata ttttaaattc tctaaacctg ttttagataa
    66721 aaataatttt ggttcttcga ttaaataccc aacattatca ctgcttataa tattacctga
    66781 agtcggttta ttattctgaa caagaatttt catcaacgta ctcttaccaa ctccatttct
    66841 ccctgctaga ccaacaattt cacccttgtt aagtgcaaaa tttatatctt tgagaatgat
    66901 tgaataacca taatgcttac ttacatttat aacttacatt ttttattcct ccattaatat
    66961 tcatggtttg ctctttgatt cttattgagt ttaaaaagtt gcacctcttt ttaacaatat
    67021 tatatcatat atctaactta atgcaatata taaatgtcat tttgtaaaat tttattaaca
    67081 aaaaactctc tacaacaaaa taatagagag ttttctgctt attaattttt ttcaaaatat
    67141 ctaagacatc gcttctttgt ttaatttgat aggctttaat acctaagctc cgactttatc
    67201 acttaaaaaa taaaaaagga cagctaatct cttgcgcatc aagggatttc gccattcttt
    67261 aatctcgttt aagtgttgta tatggagctt tgcataattt tttaaaacta aacaactaca
    67321 ttaagcacga actgtgacgc tggttccatc ttccttataa agattgataa gcccctcttt
    67381 aagagctcga accatgtctc cagcttgaac aggttgtggg actttaatag tcaatagttc
    67441 cattggattt ggagcgcggt cgattttatt gcctttggca tcatgcaaat cttcaatata
    67501 ggtttcaaaa tgacggaaac ctggaccata aaactcaact tggtcccctt cgttaatgac
    67561 gttttgttga cgaatagttg ctgtttgtgc cgcatcatca taagaaacca cttcagcgac
    67621 aaacttgtac tcagggattt tacgacgagc accaaacaac tgctcatttt cagatggtgt
    67681 accatagtaa aatcctgtag ccagttcacg ttgggcaacc ttccacatct cgtccaccaa
    67741 gtcttgtttg atagcttcaa acttttcagg actttcaaga taggcatcca cagccgcctt
    67801 gtagcagttg gttactgttg atacatagtg aatagactcc atacgtcctt cgatttttag
    67861 actgtccaca ccattttcaa tcatatctga gatatggtca atcatagaca tatcaacggc
    67921 tgacattgaa aattcttctg gaatctcacc ctgcaaactc ttacgttctt tcccaaatgg
    67981 catatcgtaa aggtcgtact tccaacggca tgactgagaa catccaccac ggttggcatc
    68041 acgcatactc tagacggatt gttttgacaa ttctaacctt ttagactttg cataataact
    68101 gttaaacagt cgaaaattac cccagtttta acaagtagtc aaaataccag ataaagtaaa
    68161 aaggggctag gaaaaaagtc tttaaaatct taaaaacgca tagtatcagg tattgaacaa
    68221 tcttgatatt atgcgtttta ttgtgggaag atttacttca ttttctcttg gaattgagtt
    68281 ttctcctact tcaaaactag atgatttgct atttaaaata gcgttcctta tgattttggc
    68341 aacctggatt aaagcgagaa aaacaaaaga ggcaacttaa gctttcttta tattgcttat
    68401 atgttaatag ttttagacaa acaccacata aaataggctt atcctgtatc aaagataagg
    68461 gataaggctc aaaagggtga ttttctaatg aatcatgaca ccgataacaa gcatagtact
    68521 ttttacaatc atagcattgt aaagcaataa tatccaactt gctatggtaa tgaatgcatc
    68581 ttgtttgctt atccactaag aaaccctgtg cctctatcat ttccttttcc tttcttaagc
    68641 tcgaactgtg acgctggttc catcttcctt ataaaaattg atgagtcctt cttttaatgc
    68701 acgaaccatg tctcctgatt gaacgggttg tgggacttta atagtcaata gttccattgg
    68761 atttggagcg cggtcgattt tattgccttt ggcatcatgc aaatcttcaa tataggtttc
    68821 aaaatgacgg aaacctggac cataaaactc aacttggtcc ccttcgttaa tgacgtttcg
    68881 ttgacgaatg gttgctgttt gtaccgcatc atcataagaa accacttcag cgacgaactt
    68941 gtactcagga attttacggc gagcaccaaa caactgctca ttttcagatg gtataccgta
    69001 gtagaaacct gttgccaatt cacgttgggc aaccttccac atctcgtcca ccaagtcttg
    69061 tttgatagct tcaaactttt caggactttc aagataggca tccacagccg ccttgtagca
    69121 gttggttact gttgatacgt agtgaataga cttcatacgt ccttcgattt ttagactgtc
    69181 cacaccattt tcaatcatat ctggaatgtg gtcaatcata gacatgtcaa cggctgacat
    69241 tgaaaattct tctggaatct caccctgcaa actcttacgt tctttcccaa atggcatatc
    69301 gtaaaggtcg tatttccaac ggcatgactg agaacatcca ccacggttgg catcacgcat
    69361 actcatgtgg tttgaaagag tacaacgtcc agagtatgaa atacacatag ctccatggac
    69421 aaaggcttca atttcaacat ctgtacgttt gcggatttca gctaattctt ccattgaaac
    69481 ctcacgcgct aaaacgacac gagtcaagcc tagctctttc cagaactcaa gggtttcata
    69541 gttagtggca ctggcttggg tagaaaggtg gatttcaagg cctggtgctt cagtcgctgc
    69601 aatcataatc aaggctgggt cagatacgat aactgctgca atcccgatat cacgcagttt
    69661 acggaaccac tcaccagcac cagcttcatt tccttcgtgc ataaccatat tagccgctac
    69721 atagaccttg gcaccatact tggtcgcaaa ctgcacgcct tcttccatct gttcgaaagt
    69781 aaagtttccc gcacggctac gaagaccata ggcctgacca ccgataaaga cagcatctgc
    69841 tccatactga acagctacct ttagcttctc taaagtccct gcaggtgata aaacctcagg
    69901 acgttttaat gtttttgtca tgatttctcc tatttgcaat ataaaagttt gacatttttc
    69961 cttctcattt tatagtaaat aaaggataaa atcaagccta gacggattgt tttgacaatt
    70021 ctaatctttt agactttgca taataactgt taaacagtcg aaaattatcc cagttttaac
    70081 aagtagtcaa aaagtctaga aaagtaaaaa ccagtatcca aagatactga ctcgtaaaaa
    70141 tacataaatt agtccttaga tgactactcc cactctgttg ctcctataat ggaaaaggat
    70201 tgatacagtc tagaatatcg cttttttatt tattattctg atataaaact gttagaattg
    70261 attttttgtt ttatacccaa atatgaatag aaacgtagct aataagttga ataacatatt
    70321 tggaaaaatg agaaatagca atattactag aacttttaga aacaatcaat attttaaaaa
    70381 aaaaaagctc aaagaattta ttaaaccatg ttataataga tatagctata attttattta
    70441 taacaagagg atagaaatga ccgaattaga aagaaaaaat cgaaaaatta gctaagaaat
    70501 attctgataa cttaaacatc aaagttcaag agagagttcg tgaaatggca aatgataata
    70561 agagccatta tttgatatac agagttttag gtatttcatt tgaagaagga gaaaatatcg
    70621 atttgtatca aaataaaggt cgttttttat acaaatatgc tggttcattt ttagaagaag
    70681 ctgcagtact atgctttaac gaaaaatttg gtacagaaaa tacttaaaaa gttaacattc
    70741 ctaattctga aagtacaaaa cctaagactt ttgaaattga ttgtttagtc ggagaaaaac
    70801 acgcatacga aataaaatgg tgggatgcaa ctacagatgg agaccatata actaaagaac
    70861 acactagaat aaaagttatt cataacaaag gatatatacc aattcggtta atgttctact
    70921 atccaaatag aactcaagct ataaaaattc agcaaacttt agaaacattg tataacggta
    70981 ttggagggaa atattattat ggagattctg cctgggaaca tttaagagca gtgaccggta
    71041 ttgatttact tagtattcta acagatattg caaataaaaa aacaggggta aaatcaaaat
    71101 gacagtatta aaaggagata acttagaaat attaaaaact attgaatcct caagtattga
    71161 tttaatctat atggaccctc ctttctttac acagaaaacc caaaaattat ctaataacaa
    71221 aaatattatg tattcattcg aagatacgtg gacttcgatt gaggattaca aagaattttt
    71281 gtctataaga ttagaagaat gcaaaagagt gctaaaaaat agtggcagta ttttcgttca
    71341 ttgtgataaa attgcaaatc atcatattag attaatttta gataatatct ttggagcaga
    71401 tatgtttcaa agcgaaatta tatggaacta taaacggtgg tctaattcaa aaaagggatt
    71461 attgaacaat catcaaaaca tttactttta ttcaaagtca aaagatttta aatttaatac
    71521 aatttttaca gagtattctt ctactacaaa tatcgaccaa atactagtag aacgaaaacg
    71581 aaatggaaac tctaaaacta tatataaagt tgataataat ggtgactata ttctagcaaa
    71641 agagaaaaat ggagttcccc tttcagatgt ttggaatata ccatttctta atccaaaagc
    71701 taaagaaaga gtaggttatc ctacacaaaa acctattctg ttattagaac aaattataaa
    71761 gattgctact gataaaaatg atatagtttt agacccgttt tgtggaagtg gaactacttt
    71821 agtagcctcc aagattttga atagaaatta tatggggatt gatttatctg aggaagctat
    71881 caatataact cagcaacgtc tggaaaatgt tataaaaaca agttcaaatt tattgaataa
    71941 aggaatcgaa gcatatagaa ccaaaactga ggaagaggaa aacattctta aattattaca
    72001 ggcaaaaatt gttcaaagaa ataaaggaat tgatggtttt ttacctaaac attttcaaaa
    72061 aaaaccgata cctataaaaa ttcaaaaaaa taatgaatgt ctgaatgaga gtatctcttt
    72121 attacagaat gctataaact ccaaaaaact tgattttgga gtagttataa aaactcattc
    72181 agataattta ttatttgatt ttgatacgat tcctgaaaat ataatagtag ttgaccattt
    72241 tgaacttaca atcgaaaaat ggttaagtaa aagtcaacag ttactatagt ttgcaaatta
    72301 tttacagaaa gaacaaaaaa tgctctgaaa cactgatttc aaagcatttt ttgttagttt
    72361 aaaattattc ccactcaact gttgcaggtg gtttacttgt aatatcgtag acgatacggt
    72421 taacatgatc cacttcattt acgatacgta ctgagatttt ttgaagtact tcccatggaa
    72481 ttttggcaaa atcagcagtc ataccatcga tagaagtgat agcacggatt gcaatcgtgt
    72541 agtcatacgt acgaccgtca cccataacac cgactgaacg aacgcctgtg ttaacagtga
    72601 agtattgcca aatatcgcgg tcaagtccag ctttagcgat ttcttcacga agaatagcgt
    72661 ctgattcacg aacggtttca agtttctctt cagtgatttc acccatgaca cggatagcaa
    72721 gtcctggtcc tgggaatggt tggcgccata cgatatggtc tggcatacca agctctgtac
    72781 caagagcacg aacttcatcc ttgtaaagag tattgagtgg ttcaatcaat tcaaactgca
    72841 tatcttctgg aagaccaccc acgttgtggt gtgacttgat agtttgagct gtatccgtac
    72901 cagactcgat aacatctgta tataaagtac cttgagcaag gaatttcaca tctttgagct
    72961 tgcttgcttc gtcatcgaat acatagacaa actcgttacc gatgatttta cgtttttgtt
    73021 cagggtcaga aacgccagca agtttgtcaa ggaaacgttt agcagcgtct gctttgacaa
    73081 tattcaaacc aaacttacca ccgagcatgt ccataacttg atcagcttcg cctttacgaa
    73141 gaagaccgtg gtctacgaag atacagatca attgatcgcc aatcgctttt tggagaagaa
    73201 ccccaacgac agatgagtca acaccacctg atagaccaag aaggacacgt ttatcaccga
    73261 cggtttcacg aatttttttg atctgcatgt caatgaaatt atccattgac cagtcacctt
    73321 tagccttaca aatgttaagg gcaaagttac gaaggatatc atttccgtat acagaatgac
    73381 gaacttctgg gtggaattgg ataccgtaaa tgtgtttatc tgggttttcg atggctgcgt
    73441 atgggcagtc agctgatgta cctgtacgaa caaagtcagc aggaatctca gtaaccgcat
    73501 caccatggct catcaaaaca gtctgttcat caggtgttga ttcaaaaagc gctgatggtg
    73561 tgtgagttag ggttgattga ccgtattcac gatttccagc atcacctgca ggaacaactt
    73621 ttcctccaag tttatgggtc aataactgca taccataaca gattcccaaa attggaattc
    73681 cgagttcgaa gatttctggg tcaatatcaa atgaaccatc ttcatataca gaatttggac
    73741 cacctgatag aataattcct acaggattga cttcacgaac ttcagcagct gaaattttat
    73801 ggctttttag ttctgaaaaa acaccaatct cacggatacg gcgtgaaatc agctggttgt
    73861 actggctacc atagtccaat acgatgattt tttctacatc ttgcaaatca gttgaaatgt
    73921 tgctcatctt tttcctttct caaaagaaat atcttttctc aatattctat cacaaataag
    73981 ggcgaattac caactaaaca aggcgaagtt tgactttttc tagtttattg gggtacaata
    74041 gagaaaagat agaaatgaag tgaaaaatat gctacctgct tatatgaaaa tccatgatca
    74101 gataaaaaag gatattgacg agcaccgttg ggctattggt gagaggcttc ccagtgaaag
    74161 agatttagct gagcagtttg cggtcagtcg catgaccctc cgccaagctg tatctctatt
    74221 agtcgaagaa ggcgtcttag agcgccgtgt aggaagcggc acttttgttt ccagtactcg
    74281 agtacaagaa aagatgcgag ggacaaccag ttttactgaa attgtcaaat cccaaggtaa
    74341 agttccctct agccagctca tttcctacaa aaaaaccatt cccaatgagc aagaagttgc
    74401 caagctagga atttttccaa cggacaatat tatccgaatg gagcgggtcc gttatgccga
    74461 ccaagttccc ctagtttatg aagttgcttc tattcctgaa aaattcatta aggactttaa
    74521 aaaagaagaa atcaccagtc atttcttcca aaccttgcaa aaatatggct atcgtatcgg
    74581 caaatctcaa cagaccatct atgctcgcct tgctaaagaa aagattgccc actatttgga
    74641 agttgaaaaa ggacatgcta ttcttggatt gacccaggtt tcctacctag aagatggtac
    74701 tgcttttgaa tacgtaaaaa gtcaatatgt aggcgaacgc tttgaatttt atcttgaaaa
    74761 taattagatt accacgcaaa aactctctgt cacggacaaa gagtcttttt tatttttcta
    74821 agaataaatc tttcaaagaa atcaaagtta cagcaaacaa tatcattgcc ataccaagaa
    74881 aatcaatggg ataaaattgt tcattcatta ttaagaaggc aaagaaaatc gccgatattg
    74941 gctcaattga agccaacaag cttgacttga ccggtcctat cagactggct cctttaagga
    75001 aagctgtata ggcaaagaca gtcccgataa ggataatgcc tgcaaacgca aggagaaaat
    75061 caagactagt cgggatatcg gcctgtagaa cccctgtaaa aggaagagcg accaaacctg
    75121 ctatgaccat tcccacacca atgaccaagc tgctccccca ctttttaatc aaggctatgg
    75181 gtaaaatgat atacagagca taagtaaagg cagaaaagag accccagaac agaccagcag
    75241 gtgtcatgga taactggtcc aactgcccat gtgttgcgat caggaaggtt cctccgatgg
    75301 cgaatatgat ggaaactatc tctcccagtg tcggtgccac cctatccttg atacagctat
    75361 aaattaaaat tccgacagga caaacatact gaagcaccgt cgctgttccc gcattggtct
    75421 cctgaatagc agacagatag gcgaattggt tgagaaaaag accaatcaga gcaaaaataa
    75481 gaagagacag caaactcttt ctatccttta aaaagaccag tattttatcc tttgcagtag
    75541 cataagccaa gagcatgaga attccaccag cgattaaaag acgcaagttg gtcaagacca
    75601 gagccgaaat tccgtgtgcc attaggtatt ggccactcgt tcctgacaac ccccaagcaa
    75661 taccagccac aactgttagt aaagtccctt ttaaactatt tgacatgtct ctccttactc
    75721 ttctttgcga atcaagttca tcacttgatt gcggtctaat atccattgag ctctctcgtc
    75781 cttttcatag gtacgattcg ataggaaaat agtggcttct tgcttctgac gattccacat
    75841 gataaaggta cctgtatagc ccgtatggtc tagccaatct ccttccaaat tccatgctaa
    75901 agaacgttcc ttgtcatcca aaggagaaaa attttgactt aagtctcttg caaaatcatc
    75961 tgctaaatag tgttctaaaa agatttgtaa atcctttata gtcgaaaata aaccagcact
    76021 cccagcatgt ctacccagga gacgagcctt gggatcatgc actatgcctg cctctacacc
    76081 tctaactgtt ggaacagcaa gctcaactga cccaaacttg gtttccgtca ttccccaagg
    76141 tttccagact tgatccttta aaatcacatc caaatcttga ttaaaaattc tttccaaaat
    76201 aaagcccaac agcaaaaaat ggacatccga ataaagaaag gctggctgac ttcgtctgtt
    76261 gagatgaaac atcgcttcct ttaattcagg ggctgttaaa agatcacgat taggaataaa
    76321 aggatcaagg tctgttgcat gagtcaagag ctggcgaata gtgatgtctg gataatcact
    76381 ctcaggtaaa aaatctatta ccagtctatc aatatctaat tgacctattt cccacaagaa
    76441 ggtacaaact gtgccaaccc caacaacctt gctgacacta gctaggtcat aaactagtcc
    76501 tgcctcagtc tgcaagccat gctctgggtc actctggcct aaatagaact ctgtccattg
    76561 attgtcctta aaatacgcaa aagaggctcc gggataaatc cctgcctcga tttgttcttc
    76621 tattttttta atgatcttgg tccacttcat acttcttcaa accacaattc aacattattt
    76681 ctatctttac caaggaagaa tttttcagac ttaggaataa aatattcaat agactcaaac
    76741 ttctggcgaa gacttgctat gtctaattca ttgaccaaga acttgagcat agataagtcc
    76801 caggtaaccg tattgtccac agtcaaatcc tgcccctgag ctggaataaa atcaagggat
    76861 gccccaattt cagatgattc caagaaactt tcgatatcag ttgggagatg taattccata
    76921 gaaatctcaa atttacttaa agaaattgat gccaaatctg tttgaaattc aggcttttct
    76981 cctacttcta ctagacttgc tctgtcatct tccgcatgaa tcaaaatcaa atcatcttct
    77041 ggtgagaaaa tttcaaaagc gtagccattt tgacctttat ataatcgatg aatcgaatct
    77101 gttttagata agattccttc aatttctaag ggattttcca ccttgacaat caatctagct
    77161 agtttttttc ttccctctac cttacgagta cgcatactgg gagcttcttc taaaaccagc
    77221 ttttcaagac ccgtttggtc acctagtgac agaaaggccg attcttctaa caaggccttc
    77281 attccaaggg tttcaatata aaatgtttca tttaattttc tattattagc ttttaaagta
    77341 ggaataatcc gtacaatctg atttacattc ataaattcct ccgtcacttt ttattttaaa
    77401 ggattttaga attttttaca agatattatg ctcaaattta acattattta gctatttagt
    77461 aaagatagtc tttcaaggct tttgacaaag cctgataacc agcaatactg aggtgcagtc
    77521 catcagttgt atattctttt ttgagttggc ctgcttggtc tgtcaaacaa tcaaatactg
    77581 gcacaaattc cacctgcata taggcagatg caagctcttg ataggcttga ttccagttct
    77641 gaattttttc attcgagcgg atatagactg cctgctggta ctcctctccc tcattgacag
    77701 gcaaaatgga aagcaattta atctctgtca atggataatc gcgagcaacg gattgaatga
    77761 tagcttcgag attattgaga gcctcattca caggaacatc ctttccgata tcatttgtcc
    77821 caatcagaag aaaaatttta tctactgctc caccatatag atgagcatca aggttctcta
    77881 gtaacagtcc tgtctgatag ccacgaattc ctcgattgac aatcgtcttt gaagtcccaa
    77941 atagctcctg tagaggataa tactcgacaa tggaatcccc aataaaaaga atgtttggtt
    78001 ctacaacaga aatgtgattt aggtgacgat acttggtttg aattttttct tgttccttta
    78061 ggagccaatt ttctaataac tgtactgcca cttcattctc ctttttctaa ccagttttcc
    78121 aagacttgat aaactcctcc ttggctgttg gctggtgcta gagcagtcgc cacagctttg
    78181 gctttctcat cagcattttc catcgcatag gcaattccag ccatttcaag catttcaaca
    78241 tcattttcac tatcaccaaa agccatgatt tcttgggatt tcaagtccca gcgcttgagt
    78301 aattcctcca agccccatgc tttatgaatc ccagcttgga ggatatcaat gcaaccatag
    78361 ccactggata cagctcggac acggccatca aagagagtat tgatttcttc caaaaccgaa
    78421 ctcaaacgtt cctcaccaac aaccatgctc atcttgagca caccaccaaa gaggtcagat
    78481 gttaattcat ccacaaattg catccgttgg tagaattttt caatcatttc tggagtcata
    78541 aaactttcaa gatctgtaaa aatcgtacct tccttgacaa aatcaccctt catccccgtt
    78601 acaacaaact ggtcctgaca cgctcgaccc ttgaaatgag ccaaagcctt gttgacaatg
    78661 gcgtcatccc atgtcttagc ctgaatcaat tcattgtttt caaaaatacg agcgccatta
    78721 gcaacaacca gaaccactcg atccaccaag ggactcagta gttgtctcat gcggtgaatt
    78781 tcattgcccg tcgcaatgac aaaacgaatg cccctttgat ccaactgatc taaaatcttt
    78841 tccaatcgtg ggagatcaag ctgacctcta gcatccagca aggtcccatc catatctgtc
    78901 gcaattacct taatcatcat ttactttcct ctggattcaa gctaatacca cttcaatccc
    78961 acatgttcat tcatttcttt ataggctgta tcaattcgtt ccttagtcgc ttcatctaac
    79021 tggtcacgat gactgccatc ctctataaaa tcttccaaaa tataagtttg gtaatgatac
    79081 aagggatatc cttctggtga aaaggttccc tttggtgttc gattgaccca agtaggatga
    79141 gctttagctg ttccgatagt tgtttttcca tccttcttct tgatggtgac atccatgaga
    79201 acaccacgtt cagtccactt agcattctct tcatctccca tagattcaat tcgttgattg
    79261 gaaatgaagt tccccattta atagacaatg agcttcttat ctccatcttt ttccaccgtt
    79321 tcagatggtt caacaacgtg aggacgccct ccaaagataa tatccgctcc ccaatcgatc
    79381 atcttgtgat aaagagcttt ttgttcttca gttggttcca atcgatactc aacacccatc
    79441 tgaggcatga taatggtgat atctgcttcc ttctctgccc gttcaatttc agccttcatc
    79501 ttatcttcgt ttaaatctga aagataacga ttatagtctt cctgagaaat atactgctca
    79561 attccattga aaccatagga ataggctaac aatgcaacct tgataccatt cacttcctta
    79621 atgaccagcg gagcctgaac acgtggttcg tgcgtataaa ctccgattgg agtgattcca
    79681 gctttctcaa taatatcggc cgttgaaata actccctcaa tttgcgaatc caaaatatga
    79741 ttatgagcta aatccagcac atgataacct gcctccttaa tagcatccat aacttcaaca
    79801 ggagcattaa agagaagata acccgctaaa taatgatcct tattaatggt tccttcaaaa
    79861 tcaccaatag ctaaatctgc tgcttagtcc ccttgcttga gccaaggagt cacatactca
    79921 aaattttcat gaaagtcata ggtaccgtct tcttttttaa ctgaaaagaa aagtccatcg
    79981 tggtagagca aatccccgtg ggccataatt ctggcagttt tttcctcttc ctactcctga
    80041 gacttttgct tagtcccctc ttgagaaata gtatctcgtt tttgactagt caagggattc
    80101 cttggaagct ttcaaacaac aagaccaagc ccattgataa accaactgct agcaagagta
    80161 tcgccacaaa tcccttattg ctccacttgc gataactcct aaaaagttta ccaagccctt
    80221 cataaaacga aaagctaaac caccctgatt tcgattttgt cttctttgta tcttcattct
    80281 ccctactttc ttatgcaagc cttttctttt tattatatca cagataagta tttctttcac
    80341 aattgaattg aacttcccat ctattttcta taaatcctaa atgccataat gctttcaatt
    80401 cttgtcattt tgtgatatca tgtagaggaa atgaactaat ccacagtggc ttattccaag
    80461 tataccactt gggctttggc agtagctaac tgcactaaac ataatataag gagagaaaat
    80521 gtctgcaata gaacgtatta caaaagctgc tcacttaatt gatatgaacg atattatccg
    80581 tgaagggaat cctactctac gcgcgattgc tgaggaagtc actttccccc tatctgacca
    80641 ggaaatcatc ctaggcgaaa agatgatgca attccttaaa cattcccaag atcctgtcat
    80701 ggctgaaaaa atgggactcc gcggtggtgt tggactggct gctccccagt tagatatctc
    80761 aaaacgcatt atcgctgttt tggtacctaa tattgttgaa gaaggcgaaa ctccacagga
    80821 agcctacgat ttggaagcca ttatgtacaa tccaaaaatc gtctctcact ctgttcaaga
    80881 tgctgctctt ggcgaaggag aaggttgcct gtctgttgac cgtaacgtgc ctggctatgt
    80941 tgttcgccat gcccgcgtta ctgttgacta ctttgacaaa gatggagaaa aacaccgtat
    81001 caaactcaaa ggctacaact ccattgttgt tcagcatgaa attgaccaca ttaacggtat
    81061 catgttttac gatcgcatca atgaaaaaga cccatttgca gttaaagatg gtttactgat
    81121 tcttgaataa agaaaatccc gttgcaagac ggggttttgt gttataatag aggcatgaaa
    81181 acaaatgata ttgtctatgg tgtccacgcc gttaccgaag ccctccttgc aaatacagga
    81241 aacaaactct acctccaaga agatctccga ggtaagaatg ttgagaaagt caaggaacta
    81301 gctacagaaa agaaggtgtc catttcttgg acatcaaaaa aatctctctc tgagatgact
    81361 gaaggtgctg ttcatcaagg ttttgttcta cgagtgtctg aatttgccta tagcgagcta
    81421 gattacatcc ttgcaaaaac acgccaagaa gaaaatccac ttctattgat tctagatggt
    81481 ctaaccgatc cccataatct gggttctatc ttgcgaacag ccgatgcgac caatgtttca
    81541 ggtgtcatca ttcccaagca ccgtgctgtc ggagtaactc ctgtcgttgc caaaacagcc
    81601 acaggtgcta ttgaacacgt tccaattgcc cgagtgacca acctcagtca aaccttagat
    81661 aaactcaagg atgaaggctt ctggaccttt ggaacggata tgaacggtac tccttgccac
    81721 aagtggaata caaaagggaa aatcgccctc atcatcggaa atgaaggaaa aggcatctct
    81781 agcaacatca aaaaacaggt cgatgaaatg attaccattc cgatgaatgg acatgttcaa
    81841 agcctcaatg ccagtgttgc tgcagccatt ctcatgtacg aagttttccg aaatagacta
    81901 taaaaaagtt tccagtcatc tgattggaaa cttttttatg attaactatg ttctgtgata
    81961 aacttgtagg cttcttgacc agcgatagct ccatctccaa ctgctgttgt tacttggcga
    82021 aggtctttca agcgaacatc tccaactgca aagataccgt cgactgcagt cttcatgtgg
    82081 ctatctgtca caatccagcc tgcctgatct tggatattca attctttaac aaaatcgcta
    82141 agagggtcca aaccaacata gataaagaca ccaccgaagg cttgctctgt cacttgacct
    82201 gttttcacat tttcaaatac gactgattct actcggtttt cacccttgat ttcccttact
    82261 acagaatccc agataaagct gattttttca ttcgcaaagg agcgatcttg taaaaccttt
    82321 tgggcacgaa gttggtcacg acggtgaaca atggtaacag tcttagcaaa acgagtcaag
    82381 aagagggctt cttcaacagc tgaatctcca ccaccaacta ccaataaatc ttggtcacgg
    82441 aagaaagcac catcacacac agcacagtaa gaaacaccac gactgttcag ttcttcttct
    82501 ccagttactc ccaaaggacg gtgtttagaa ccagttgcta cgataactgt acgtgtttca
    82561 tatgtttggt catcagtcat cactttctta aaatcaccat ggtcttcgac attttcaaca
    82621 taaccataaa tgtgctcaac accaagattt tcaagtggtt caaacatctt ttcagccaat
    82681 tcaggtccac taatattagc gtatcctggg taattttcga tatcagatgt attattcatc
    82741 tgaccacctg gcagaccacc ttcaatcaaa gctactttta gattgcttcg agcagcatac
    82801 aaggccgcag tcatccctgc aggtccagca ccgataataa tagtatcgta catatagatt
    82861 ccttctttct tgttgtaact atctttattc taactctttc ttgtcaatca cgcaaggatt
    82921 atgccttgaa aacaagaatt aaactcataa ccgcaaagga taatactggg acaaccaaga
    82981 ctccaatcat aatcatatca tagagatggg cttggcgagc cttggctgtc ttatcaactc
    83041 ccgacatggc tctcagacca atccaaatcc ctaaaaaaat cagaacaagg atggtggtca
    83101 agatcaaact ctcgaaatat aaagaaaata gttgcagtag catgatttct ctcatttcta
    83161 tcttttttaa agagtaaact cagctagtcc aactaactga gttttccttt atctattata
    83221 tcaaatataa gtccgtttgt aactagcgaa gaattctttt gtccgctctt ctttaggggt
    83281 gtggataatc tcatctggag ttccagactc gatgattttc cccttatcta agaagagaat
    83341 cttatccgca acttgggcta caaaggacat gtcatgactg accaaaatca tggtctgacc
    83401 tgacttagca gcatctgcaa tagacttttc tacttcaccg accaattctg ggtcaagggc
    83461 tgaagttggt tcgtctaaga gcaaaacatc tggtttcata gcaagcgcac gcgctagggc
    83521 aacccgttgc ttctgtccac ctgataaatg gcgaggataa tggttttcac gatccgaaag
    83581 cccaacctta gccaactctt ccttggcaat cttagtcgct tcttggtcag ataatttctt
    83641 gacaacaacc aagccttctt tcacattatc aagtgctgtt cggcgttcaa acaaattaaa
    83701 ctgttggaaa accatagaca acttacggcg tagggcaagg atttcttctt gagtgatttt
    83761 agaaaaatca actgaaaaac catcaatctg aatagagcca ctgtcaggtg tttcaagata
    83821 attgagactg cgaagaaagg ttgattttcc agctcctgaa gaaccaatca aggctacgac
    83881 ttctcctttt tgaatatcca agttcagatg atccaagaca gtctgtcctg aaaaggattt
    83941 gcttaaattc gaaatcttaa tcattaacga aggtctcctt tcacatctgt ttgcactata
    84001 tcaggtgcag aaatagccat ttttctctcg atgaaacgac cgaggctttc aattccgata
    84061 ttgactaccc aataaacaag ggcaacggag atgaagcgtt caaaatagcg ataatcagct
    84121 ccacctagaa tctgagcttg ggcaaagact tccacaacac ccgcactaaa agctagagat
    84181 gttcccttgg tcaaaccgat aagggaatta atcaaggttg gagtagctac caccgctgca
    84241 ttaggaataa tcactcgtcg ataaacttgc gctcgggtca tacccagact gcgtgccgcc
    84301 tcaatctcac caggattaac tgagagaatg gctgcacgaa tggtttcact agcataagct
    84361 gcctcattaa aggcaaaggc gacaatcgca aaaactgcag ctggaatcgc attgatattg
    84421 agaccagttc cccattgctg attgagggct ttcaaagcca aagggattcc gtagtaggtc
    84481 aacatgagtt gcaccaaaat cggtgtccct tttaagaaac taacaaagaa ggcctgcaag
    84541 ggatataaaa tcttgacacg attgatcttc acaatggcaa aaagaagcgc caaaaccaag
    84601 ccaaaaaggg caccaccaat tgtcaacata attgttgttg gaagttgttg gacaattcta
    84661 gggattccat caaagaccga acgtaggcta aacagcttgc catccggaat caattgcatc
    84721 aagttttggt accaatctga tgctaaaatc gttgtaacat tcataaaaac atcctcttct
    84781 gataatgatt cattctacca tgcttctgcc gtcaatgaaa ttatttgcta cggtcagata
    84841 cagactttgt ctacctacta gtttatcata ctttgaaaca gggaagttat atattttatc
    84901 tatcaaagag atagataaaa actatttcag tcccagttct tcataagatt ttcgataacc
    84961 gatttgctta acagttccat tttctactaa aatgggccgt tttaacaaca taccgtcact
    85021 tgctagcaac tcagccgctt cttggtttga caaacttcct accttatctt ttagccctaa
    85081 ttcacggtat ttgataccac tggtgttgaa aaattgcttc aattcaaatc ctgaggtttc
    85141 tagccaattc aaaatgactt cttggctagg tgtttcttcc acgatatgga cggctttata
    85201 gtccacacct aattgattta attcttgttt tgctttttta caagttgaac atttggggta
    85261 ttcgataaat tctaacatgt gcttctcctt ctattgtttc tatctttaaa atctactcct
    85321 tcatgctcca agagccaagc tttcttttcc actcctgcag cataacctgt cagacgcttg
    85381 cctgctccca acacacgatg acaaggtact aggatagacc aaggattgcg tcccactgct
    85441 ccaccaattg cttgagcaga agccacttgc aggtcttgag caatttgtcc ataggtcact
    85501 gtctgaccat aaggaatgcc ctgtaaatag tcccaaactc tcttttcaaa attcgttccg
    85561 attggcgcca agagcaagtt ggataaatcc tgaggcttgc ctttaaagta atcatctaag
    85621 caagcaataa ctgggtctaa aataggatga ctaacaactt cttctatcgt ttcatctcct
    85681 agtcccctct caaaatgctt ctgctcctga acccaaattc catacaaata atggtcatca
    85741 gctacaagtg atagaatacc aattggtgag gagtagagga tttttacata cttcttttgc
    85801 attatttctt taatttttga taggccaagc gttcgccatc tactggcacc ttaccaactt
    85861 gtttaaaacc aagtttttca aaaatatgtt gcataacctt gttttcagca tgcgtatctg
    85921 agcgaaaatc aagataatca aaaccttcaa tcaagccctc taagaaggtt tgagcaactc
    85981 cttttccctg cacatctgct gccacagcaa tacggtgaaa gactagatac tctgactctc
    86041 cagcttgcca gtttccctca taaatagctt cataggcctc ctctggactc ttggtcacag
    86101 cagcataggc tagcagttct ccctcttcca aggctacgta ggcttgccct gagatgatat
    86161 catcgataat aacatctgca tttggatagc cattttgcca ctggtcacta ccagcatctg
    86221 ctaaacattt tttggcatcc tctatcacct gcatgatggc atctacttca tttggaaaag
    86281 ctaaacgaat ttccatcttt tttcctcatt tctgactagt ttctcccatc atagcataat
    86341 ttaagtattt ctacaagcag ttaaaacttg actttgtgtt tttgttattt tataatctag
    86401 ttatcaaaac tatataaaaa ggagttgaaa atgaaaacta ccttttccta cccaaaatgg
    86461 gcagaaattc caaacattga cctctatctg gaccaggttt tgctctatgt caatcaggtc
    86521 tgcgccccta tctctcctaa taaagacaag ggcctaacag catctatggt caacaattat
    86581 gtgaaaaatg gttacctgac aaagcctgac aaaaaaaaat accaacgcca acagattgcc
    86641 cgtttgattg ctatcacaac cctcaagtct gtattttcta ttcaagaaat agcccagaca
    86701 cttaatactc tacaaactca agcaagttca gaccaactct acgatgcttt tgtggactac
    86761 atgaaccaag gaattgaccc agctaaccct attatccaaa ccagctgcca aaccgttaaa
    86821 ctttatcatc aaactctaga cttaatcgat catactcaag aggaggtaat ccaatgaaca
    86881 ctagtcttaa actcagcaaa caactcagtt ttggagagga gattgctaat agcgtgaccc
    86941 atgctgtggg tgcagtcatc atgcttatct tgctgcctat ttcatccatc tatagttatg
    87001 aagcacacgg atttttatcc tctatcggcg tttccatttt cgtcatcagt ctctttctca
    87061 tgttcctatc atccaccatt tatcactcta tggcctatgg ttcgacccac aaatatgttt
    87121 tgcgaatcat tgaccattct atgatttacg ttgccattgc cggctcatac acgcccgttg
    87181 tcttgacctt gatgaataac tggtttggct atctgattat tgtcatccaa tggggaacga
    87241 ccatctttgg tattctctat aaaatctttg ctaaaaaggt caatgagaaa tttagccttg
    87301 ctctttacct gattatgggc tggttggttc tggctatcat tcctgccatt atcaatcaaa
    87361 cgacacccgt tttctggagt ctcatggtaa ctggcggact ctgttataca gttggagctg
    87421 gattttatgc caagaaaaaa ccttatttcc acatgatttg gcatctcttt atcctagctg
    87481 cgtccgtact ccaatacatc gctattgttt attacatgta aaaaagttga gaaattcaat
    87541 ctcaactttt ttctttacac atattgataa agtactggtg caagcgcaca tcatcagtca
    87601 attctggatg aaaagaactt accaacatat ttttttcttg ggctgcaaca atttgattgt
    87661 tcactgttgc tagaatttct acaccctcac caacactact gataatcgga ccacggataa
    87721 aggtcattgg aatcttgcca actcccttac attctgcttc cgtgtagaaa cttcctaatt
    87781 ggcgcccata agcattacgc tcgaccacca tatccatagt tcctagatga ctctctttct
    87841 gagaagtgat ttccttagcc agcaaaatta agcccgcaca ggtcccaaac actggtaagc
    87901 cagatagaat ggcttctcgg atgggaagta gcatgttctg gtcacgtaag agcttgccca
    87961 tggttgtaga ctcaccacca ggcaaaatca aacccgacaa gtcactctga tcttgctgaa
    88021 aatcatctag atttctgagt tctacactct cgacacctaa ttgatctagc acttttgcat
    88081 gttctgcaaa ggccccttgc aaggccaata ttccgatttt catctatttt cctcgttcag
    88141 ccatgagaat ttggatttca ttttcattaa taccaaccat ggcttctcct aaatcttcag
    88201 agatttgagc taggatttga ggattacgga agttagtcac agccttaaca atggcactcg
    88261 ctcgtttaac aggatctcct gacttgaaaa tacctgaacc gacaaagacc ccctctgccc
    88321 ctaattgcat cattaacgca gcatctgctg gcgttgcaac acctccagca gcgaaattta
    88381 caactggcaa ttttccatgt tcatgaacat attggaccaa ttctacaggg acttgcaaat
    88441 ccttggcagc aacataaagc tcgtcctcac gtaagttttg aatgcggcga atttcctgat
    88501 tcatcatacg catatgacga acagcttgga cgatatcccc tgtccctggt tctcctttgg
    88561 tacgaatcat ggaagcacct tcagcgatac gacgcaaggc ttcacccaaa tccttagcac
    88621 cacagacaaa aggaacttgg aattctttct tatccacatg gaaacggtca tcagctggag
    88681 atagaacttc actctcgtcg atataatcaa tttcaatagc ctctaaaatc tgagcttcaa
    88741 caaaatgccc gattctgacc ttagccatta ctggaatact aaccgcttct tggatttcct
    88801 taatcatctt tgggtcgctc atgcgggaaa ctcctccagc tgcacgaata tcagccggaa
    88861 ttcgttccaa ggccatcaca gctgccgcac cagcagcttc tgcgatacga gcctgttcag
    88921 gattctgcac atccataata acaccaccct tgagcatctg tgccaagttt ttatttagtt
    88981 cataacgatt ttcagtcatt tgttttatcc tcatcatttg tattggtagc taccttttca
    89041 ttttaagtca gaacagaatg aagcacaaga taaaaaaact ataattgtat ggggacagat
    89101 tggctaaaaa ctatctgacc ttaacttaag gccagatagc tcattcattt ttatttttca
    89161 gccgtaaggg cagccattgt gatgtagttg tatggtttat tgaagtgtgg caagaagaag
    89221 aggtctgtca atgccaattt atcaattgtc acatgctctt ggatagcaag tgagaacatg
    89281 tggattccca tgctaattgc aatatcatgt gaaaccattt gggcaccaag aatttcacgg
    89341 ctatctttgt caaagacaat cttaattgct acttcatggt tgtcatgttt catgaattct
    89401 ggtttttgaa gatcgttaaa gcctgtttca gttgcgttgt aaccagcagc tttcgctttt
    89461 tcaagagtca aaccagttga aaccatgtga agaccgtaga ttgagatacc atttgaacct
    89521 tgaacaccga ttccttccaa ttcatgtcca caagcattgt aggcaccaac gataccagtg
    89581 cgaacagcat ttgaagcaag agcgatatag cttgtatctt tacgagcatt gtcataaaca
    89641 gtcgcacagt caccaacagc gtaaacgcct gggatagatg tttcttgttt cttgtctaca
    89701 aggaaggcac cgttgcggaa gagttcgatc ttaccatctg caagggctgt gtttggacgg
    89761 aaaccaactg caaggataac catatccacg tcaaagcttt ctttgtcagt aatcaagcgt
    89821 tcaactttac cgtcaccttc gattgcttta acagtttgac ctagagccaa gcggatgttg
    89881 tgatcttcca agttcttcgc catcatttgt gtgaagtctt tgtcatagta accgttcaag
    89941 acagtatcaa cgatatcaac aaggacaact tcttttccaa gacgttcaaa ggcttcagca
    90001 agttcaacac cgatgtaacc accaccaaca acggcgatac ggtcgaggtg ttggctcttg
    90061 tcagaaagtt tattgataac ttcttcagca ttttggtaca atttcacgaa ttgtacgttt
    90121 tcaagagttg ctttaaattc gcggtttcct ttaacaattt caacaccttc gattggtggc
    90181 aagattggtg tagaacctgt agcgaaaatc aatttttcgt atgattcttt gtgctctttt
    90241 ccttcaactt ccgctgtaac tactttgtta tcatagtcga ttgaaagaac aggtgagttc
    90301 atgtaaactt tagcaccttt agcttccaat ttttctttat cagaatagaa caagccttca
    90361 gcaccgtcaa tttgttcacc aatccaaaga gccattccac atcctaggaa agagatgtta
    90421 gagttttggt caaatacaac aatttcgttc tcatttccaa aattatccaa catggtattg
    90481 atacatgctg taccagcgtg gttagcaccg actacaacga ttttactcat aaaaatttcc
    90541 tgccttcatt ctaaatttac cttactagta taccatttac cgttagcgtt tacaaggggg
    90601 ctactattat ttcagcattt tttatcaaaa ataattcccc atttatcctg ttttcaagcc
    90661 tcatgaattt tatgagcata tttcttgact ttttccaaat tttgtttgtg aaaattctaa
    90721 ctttatggta ttataataac atgaaaatga aatgtaaggg cttcaattta gatgattatt
    90781 ttatattaca acttattttc tataagagaa aggagttggt agcttgactc ttcgttcaca
    90841 ttctgaacgg ctaatgggga ctactatcac tatttcatta gtggatgagc aagccgatat
    90901 ctttctccaa aaatcctttg acttgctcaa agagcttgaa taccgcttca atgccaatag
    90961 tcaagaatca gagttgatgg aaatcaatta tcaagcagga atagcccccg tcacggttca
    91021 tccagacctg tttgagctga tttcacttgg gttagagcat agcctagcgc tctctagcca
    91081 cctcaatatc agcattggtc ccttaattca aacctggcgt atcggttttt cagatgccaa
    91141 ggtcgcccag cctcaagaaa ttgaatcggt gctgcctcta atcaatcctc atggtatcga
    91201 gttagattct tctacttcta ctgtgttttt aaaacagaaa ggaatgaaga tcgatctagg
    91261 ttgtttagcc aaaggataca gtgcggataa ggttgcccaa tttcttagga aagagggggt
    91321 gacttctgcc ttgatcaatc tgggagggaa tatcctgacc attggaaaaa atcaggcaag
    91381 aggggataac ccatggcaaa tcgggattca agacccagcc aatcctaggg gaaatcattt
    91441 aatgaccatc cctgttgtca ataaatctgt cgtgacttca ggcatttatg aacgtcacct
    91501 gaccgtcgat ggacaagatt accatcacat ttttgacagt caaacaggat atcctgttga
    91561 aacggaacta gcgagtctaa caatcatctc tgataaatca gtcgatggcg aaatctggac
    91621 gactcgactc tttggagaaa gacctgcttc tatcctctgg caagtcgaaa gtttggaggg
    91681 catcgaagtc atcctcatcg ataaagaagg ccacctaagc tgttcttcag gaattcctac
    91741 tctatagaga caactgtttc aatggaattt taaaattgta ttatgtaaaa agagaaagga
    91801 aatctcatgt taaaacttat tgctattgtt ggaacaaatt caaaacgttc tacaaaccgt
    91861 caattgcttc aatacatgca aaaacacttt gctgacaaag ctgaaattga gcttgttgaa
    91921 atcaaggcca ttcctgtctt caacaaacca gctgacaagc aagtacctgc tgaaatattg
    91981 gaaattgctg ctaaaatcga agagacagat ggcgttatta tcggtactcc tgagtatgat
    92041 cactctattc cagctgtttt gatgagcgct cttgcttggt tgtcttatgg tatttaccca
    92101 cttttgaaca aaccaatcat gattacaggt gcttcttacg gtacgcttgg ttcatctcgt
    92161 gcccaattgc aacttcgtca aatcttgaat gctcctgaaa tcaaggcaaa tgttcttcca
    92221 gatgaattct tgctctcaca ctctcttcaa gcatttaacc caagtggcga cttggttgac
    92281 cttgatgtta tcaagaaatt ggatgccatc tttgatgact tccgtatctt tgtaaaaatc
    92341 acagaaaaat tacgtaatgc acaagaatta cttcgcaaag atgctgaaga ctttgactgg
    92401 gaaaatttgt aagataggag accaaaaaga atgaaatttg ttggacttgt tggatcaaac
    92461 tacgatcaat catataaccg taagctcttg gaatttatcc gtcgctactt caaactcaaa
    92521 tttgaattag aagttcttga aattgacgaa gttccaatgt ttaaccaaga tgaaaaatgg
    92581 gatgaaagtt tccaattacg ttatttatat aacaaaatta ctcgtgcaga tggtgttatc
    92641 attgctactc ctgagcataa ccacactatc tcagcttcac tcaaatctgt acttgaatgg
    92701 ctttcatacg aagttcatcc atttgaaaac aagcctgtta tgattgtggg tgcatcatac
    92761 tatgaccaag gaacatcacg tgctcaagtt caccttcgta aaatccttga tgctccaggt
    92821 gttaatgcct acacgcttcc aggtaacgaa ttccttcttg gtaaagctaa ggaagctttt
    92881 gataacaacg gaaatatcac caacgaaggc actgttaaat tccttgaaac ttgcttagat
    92941 aactttgtta aatacgtagg agtcgtttcg aaattgaaaa aaccaaaacc aatcgaatca
    93001 gaagacttgg attgtggaaa accaatcgct acaaccatca cagaagttga ccctgacgat
    93061 ccagaatggg tagaaaaagt tgcagcaatc actggtgctg tttctggtga tacctatgtc
    93121 aaattggacc acggtatcct aacagttaac caaattgata tgttcttgaa agctatgcca
    93181 tttgaattga catacgctga cgataacaac caattcctct actacaacaa cgctcaccaa
    93241 gacccagaca ctatgttcgc taaacgtgta ccacctcaat caggtagccg tatgtcgact
    93301 gttcatggtt ctcttccacc agcacgtatg aagaacgtag agtgggttat cggaacactt
    93361 cgcaacggaa accaagaata cgtccgtacg atcgttccag gttctcctgc aggtgttatc
    93421 aacactcaca actaccaagc aatgtactat cctgatggat catacgctgg tatcaatgaa
    93481 atcgtcttta acttccaacc atggcttgac tggtacctaa aagagactgg tcaacgtttg
    93541 gtgggtggta gcggaccatt tgctcctgct gccggaggtc atggagacgc cgatgctact
    93601 tctggcgctt ctgattcagg ggatgctgga ggccacggtg gtgacgcaga tgctacagcc
    93661 ggtgcaagtt actaatgata gtttttagga accattatgg ttcctttttt agcgaaaaaa
    93721 gactagcaaa cacaaactgc tagtctcttt gttatcgttt catctatctt tgtttaaaaa
    93781 aagagtacat attatgaatt tgggtcatca agactacggc catgtaatcc tttttcacgt
    93841 tgtacttggc gtagtttttc tggtgtaaca tcgtttcctt cttcgtccac aattttgatt
    93901 ccttcaatgt gatgacgaac agcgcgacga taaccttcga tgtactcctc acgtagtttg
    93961 gcttgttcca ctttttcttc tagtgttaag ccttctgttt ttttcttttt agcaagctca
    94021 ttgatacgag caattttttt cggatccatt tcttctcctc tgtaataaga taaagtccgt
    94081 ttatcaaatt ttatttagtg ttaatttggt taaaacaagc aaacttagct gctttcttgg
    94141 ttagttgtga caagattgcc aaacgatttt gacggacagc ctgatcttca gccattacca
    94201 tagtattttc aaagaaagca tcaatgactg ggctaagcgc aaagagttgt ttcaattgct
    94261 gacttgcagg tcctgataaa acgagtgttt ctactgcttc tgccaaagct ttttcttggt
    94321 cattctcaaa tagtgctgaa tcaaccgtag caaccccttc tgccttctca gccaggttaa
    94381 aggcacgaga aagtgattca acagatggtt taaaatcttc ttccttgctt acttctacga
    94441 gagcacttgc tgcttccaac atatctgcca caacaaagtt tgaacctgca agaactgctt
    94501 ccttgatatc ttttggagta gagcccatca tcttatcaac acgagccttg ataaagtcca
    94561 taacctctgc tttattttca taagtcaaac tgtcaaattt caatgcataa aggctatcaa
    94621 tcagctcatc catagcaatg tgccaaccaa aggcatccaa gatacgaacc acaccttgag
    94681 ttgcacgacg aagggcataa gggtcattag aacctgatgg aatcaatcct actgagaaga
    94741 aactcaaaat cgtatccaat ttgtctgcaa tggctagaac tgcaccgacc ttgctctctg
    94801 gaagttctcc ttcagctgat gtaggcatgt agtgttcacg aatagcagct gccaccgctg
    94861 gagtttcacc agcaagaagg gtgtattttt cacccataat tccttggagt tcgtcaaatt
    94921 caccaaccat acctgtcaac aagtcaaact tgtaaatggc tgctgcacga gcaaggtcaa
    94981 ctgtttcatc cactgacaaa ccagcttttt ctgccaaaag tacagtgatt tgacccgtac
    95041 gaatcatgtg ttcacgaagg gaaccaatct tctcatggaa ggtgacattg tttaattttt
    95101 caacaagatc tgaaatcacc aatttttggt cttcacgcca gaagaattct ccgtcttcca
    95161 agcgggctac caagactttt tcatttcctt tgatgacatt tttcaaacgc tctgcgtttc
    95221 cgttacgaac agaaatgaag tttggcaaga gttttccatc ttgatcacga acaacaaagt
    95281 aacgctggtg ttccttcata gaagtcacca agacttcttc tggaacttca aggtatttag
    95341 catcaaaact tcccatgaag gcagttgggt attcaaccaa attcaagact tcattcagca
    95401 aatccgcatc aatttcgata cgtacaccat gttttgcctc aattttcttg atttggtcaa
    95461 caatcatttg ctcacgttca catggatctg cgattacaaa ctgcttacga aggtcttctt
    95521 catagctcaa tgctgactga attttggttt ctttccccaa gaaacgatgg ccacggctca
    95581 cacgacttcc cttgatatca aggaaatcca agtcaaactc ttgctcatcc aagagaacag
    95641 ttaaagtgtg aacagggcgg atgtattcaa agctatttcc cgcccagtgc atgctgacag
    95701 ggaaagtcaa tgacttcaag acatctacaa caccaggaac aatggcttca actgcttgac
    95761 caacttcttc cttagtgaca tagacatatt cttcaccctt gatttcacgg aattcgatat
    95821 cttcaacagt caagcctttt ccacggacaa atccttgagc tgctttggtg aagtttccat
    95881 cactatccaa ggcaattttc tttgctggtc ccttgaaatc ttctgtcaaa tcagactgtt
    95941 tgtctgataa accagtcaca cgaacagcca aacgacgtgg tgttgagaag gtttgaatgg
    96001 cttcaaaaga caggcggttt tccttgagga aggctgccat tttttcgcct agttgttttt
    96061 cacttggtgt gacaacatag gctggtaatt cttcaagacc gagttctact aataagtttt
    96121 ttgtcatgtt ttttctccga aaagtatctt tttattttcc agtttgcctt atgtgattgg
    96181 cacgcaagca accaacttcg ttgtttcatt gctaaaattg gagccaaaag tctccaattt
    96241 tgcctagtat ccttagtttc actaaggata ccttcatcac tgcggcaact ggctcagggc
    96301 tcactctgtt cgcccatttt cgtaatttgt cactctcttt attctgcgtc ttctgctagg
    96361 agtttagctc ttgtttcttc atccaaaagt gggtagccta ggcgtttgcg ttctgcgaca
    96421 aaggttttgg ctacgacacg ggccaagtta cggatacgag cgatatagcc tgcacgctct
    96481 gttacagata cggcaccacg cgcgtcaagc agattaaagg tatgtgaaca tttgagaaca
    96541 tagtcatagg cagggtgtac caagccttct tctaatgcac gaccagcttc tttttcaaac
    96601 ttatcaaagt tttcaagcaa catttcttgg tccgaaattt caaatgaata ttttgagtgc
    96661 tcatactcag gctggataaa gatttctccg tattttacac catcagccca ctcgatatca
    96721 tagacagagt ctacttcttg aatgtaagaa gccaagcgct ccaaaccata ggtaacttcc
    96781 gcagtcacag ggccagttgc caatccaccg acttgttgga aataagtgaa ctgagtgatt
    96841 tccattccgt caagccaaac ttcccaacca agaccagctg aaccagttga tgggttttcc
    96901 cagttgtcct caacaaaacg aatatcgtgc tccaaaggat tgattcccaa tttttccaaa
    96961 gactcaaggt aaagttcttg gatatttgat ggagaaggct tcatgaccac ctggaattgg
    97021 tggtgttggt agagacggtt agggttttcc ccataacgac cgtcagcagg acgacgtgat
    97081 ggctctacat aagctgcatt ccatggctca ggtccgatag cacgaaggaa agtgtaagga
    97141 ctcattgttc ccgcaccttt ttcattatca taagcctgca taagcataca accttggtca
    97201 ttccaaaatt gttgcaaagt aaggatgatt tcctggaaag tcaatttctt agacattgtt
    97261 tactcctttt tatataaatt acttgcgaca tgagtctgcc tcgtcgatca tacgaggcaa
    97321 gacgagttag tactgcgtct agctcaggca ctctagtgct gagcgtgggg cagtccgact
    97381 gtaaggaggt ttctgccact gatgcagtga aatgttaatt tctcagacat tgaatactcc
    97441 tttagttttt atatttcttt ttcaattaat ttctgctgaa caaaccaatc taacaaggga
    97501 aaagtttttt ctgtatttgc ccataaatga taagaatcta agaccgcttg tacactacct
    97561 aaattttcta ccaacttatc tactgtcaaa aagctgcgcc agtattcata aaaaatactt
    97621 gcatagttct tatcataagt cgaagaacca aaatcattca atgaatgcca actatacttc
    97681 ttctgaaaaa gttctacgag agattgatta caaatttttt ccgcttgaaa ttcctcttct
    97741 gtcaagaaat acttgcgact aatatattca accatcccct cttcgaacca gatataagag
    97801 tcataaccat caaaatcatc taaaaaatgt ccgaccaatg agctaactca tgtcctacaa
    97861 tctgtaagag gaaattttca gataaagaat gatagtgact ttctattgct tgagtttgct
    97921 cagaacactc gtagtccatc aactgataca aatacaactc tttccaaaca gctaaatcag
    97981 gcgtcataac cactcgtcta ttatttgtat aggttggaac agcactttcc ctaataatct
    98041 gtgtagcagc attaaaatct gaccaaataa cggcttgcgg taaatcacag actgcaagtt
    98101 cattctttaa aaaagattga taatctttca acttttcagt atttcttact acaaaatcac
    98161 gaaatgtagc tagttgacta tcgtctttta caagataaag gttgtccacg gctctccttt
    98221 ctttcacaca atagactgaa taagcaaaag aaccacatct gacaatccta ggttgattta
    98281 acctaggggc gtcagaaacg cggttccacc ctaatttatt acttcattgt ttttgaaaat
    98341 actacagaaa gcgccagccc tttattttgc cctacttggc tcccactatc ccaagctcgc
    98401 ttgaagaacg ccataagact ttctttcctg ctgactatta tatcaaaaat tagaataatg
    98461 tacaattctt tttatgattt tctagaaatc cacatcatca actcgtggag cacccgattg
    98521 aacagcaatc gtttttaagg tttctctctc ctcatgactc agttcaattc caaagcaatc
    98581 aagattagct tgaatacgag aggttgtgac agattttgga agtggtaaaa atccttctgc
    98641 caagctccag gccaaggcta tctgagcaac cgattttccg tgatttgctg ctatttcttg
    98701 gacttgcttg ctatcaaaca gttctccctg accaaaaggc ccccaagctt ccaataaaat
    98761 tcccttttca cgacagtaag ctacgacttc ctcttgatac acacctggcg ccaagcgaac
    98821 ttgattgacc gcaggaacga tagttgcagt ttcaagcaag gcatccaaat gatggggaag
    98881 aaaattgcta acgccgatag cacggatttt cccttcttga tagaggtctt ccatcgctct
    98941 ccaaacttcc gcattgcgag ttttccatgc gtcattttct ctgagcagtt ttgggttcgg
    99001 ccaatgaatc aaatacaaat ccaaataatc caagcccagt ttttctatag atttttccaa
    99061 agcttgacga gtttgctcat aggtttgctg actattccaa agcttggtag ttacgaacat
    99121 ttcttcacgt ggaactccgc tatctttgat tgcttgacca acactttctt cattctgata
    99181 aatcgccgcc gtatcaatat gacgataacc agccttcaag gcttctaaca ctgcacgata
    99241 ggcttcttct ccatccttag ccttaaaagt tccaaatccc aatactggaa tttctactcc
    99301 attatttaat tgataggtat tcatatgctt ctccttctat tttattcatc aattatagca
    99361 taaaacattt tttaagtagt actatattct gtaaaaaata agtctgtcaa atatctaaca
    99421 gacctatttt ttcttgctta ttcatcacga ctatagtaca gctcatgagc ttttaggcga
    99481 gtattgagca tctctggtat ggtcacaaag gtataacctt gatttttcaa atactcaatg
    99541 acccttggca aggcattgac tgtcggactg tgaatatcat gcatcaaaac gatagagccg
    99601 ttagctactt gatgctgaat ttctgtcaaa atagatgctt catttttact cttccagtcc
    99661 agactatcca catcccacat gataaagctc aaatccaagc tattgcgaat atcatctgta
    99721 atagcaccat aaggtggacg catgagttta gaactagaac ccagcacttt agttagcaca
    99781 tcctcagtat cagtaatctg ctttttagct tcatcaagag agagttgcga gagaatcgga
    99841 tggctccaac tatggtttcc aacaacatga ccttcagatt ttatcctctt caccaagtcc
    99901 tcattcccag aaacattttt cccaagcaca aagaaagtcg ctttaatatc atatttagct
    99961 agggtctcta atacctgcgg ggtcgttgct ggatttggac catcatcaaa ggttagagcg
   100021 acaacttttt gatgtttctt atcaaagtaa gattggtaca aggccgcatc tttttcgagt
   100081 aagtacgaag attggataac atcaaagaaa gcagatactg gcaaggctat ctcttctaaa
   100141 ttttcaacca caggacttgg ataaaggata atctgactat ccttgtaatc aaaattccat
   100201 gcagacaagt cttggtcaga gaagtttttt acaatctgct cactctggtc ttgctctatt
   100261 tttttatcct ctatgaagga ggtcaactct tttatcagct gttccttagc cttactagca
   100321 tctgaaaaca gttggtcaag tgtaaaaggt tgcccatctt ctgttaagtg aacctttcct
   100381 agactggtct tttcagtctc ttcaatctta aaagcaacta aatcatagat ttgtttggtc
   100441 acattacgat taacgactcc ctttaaacct gactcttctt tctctgtata gtagaaaaca
   100501 agattgtcct tactttctag cttgtcctta acatcttgat ttatcagctc cctaacagag
   100561 gaaatcactt tctccccttg gagaggataa taggcaatca cttcggcttg cccctgacga
   100621 aaatgctcct tctgatttcc ctcactcaat tgatcatctt tctctttttt gagcgattca
   100681 atcttttgct caaaactttt ttgctggtag atcttaaaag caataaatcc gcctaatagg
   100741 caaatagaaa ttgctaaaat accaatcaaa gccaataata catgtctcgt tttcccgtgt
   100801 ctgccacgtc ctagtctact tttattcata tttatatcat aacaaatttg agcaataatt
   100861 tcaatgatac aatttggcaa tccacaattc ctctagcaag ccaaagcatc ttacatcaac
   100921 tccaacatcc gtatctgtag agattatgta gttttctatc tatggaattt ctagtagatt
   100981 gaagctagaa tagtagacct atacttctaa aacattgtta gaaatcgatt taactgtcct
   101041 gatcgatttg tcctgttctt atttcatttt actataaaac tatgagaagc taggtcatct
   101101 gagaagtaat tactatcgac aattgcgata gcgtatactg gtgcgatgtg tttgtagctc
   101161 tggtgggtat catcttcacg ttggcgaatt ttttctaggt tttgattaac ctgactgcac
   101221 agataagccc ataggcgatt gatgaaaaaa ttctgatgat gaacctgaat ttcgatgata
   101281 acttgggttc cattatctaa ctccgccaag acgtctatac tagtatagaa atcctgcgct
   101341 gagtagggca tggaaggcaa gacgtgaatg ttacttccct ccaaaatcgt cacatttttt
   101401 gctggcaagt ccagcatatc gcggataaat tgacaaatca ttagttgggc tgatacccgg
   101461 atgtctgaga atactccttt tcctccttct attatagcac atttttaaat ctaggtttgc
   101521 tagattctat gcttctatct atttattcgg aaaagaaagc ttttcttcag aagaaagcta
   101581 atagcttatt tgaaattttc tcctctctgt tggatagtcc cgtctatcta tgttataatg
   101641 aaagaaggat ttaaaatcgg aaaaggagta tttatgctaa aattaggtat catcggaact
   101701 ggcgctatca gccatcattt catagaagca gcccatacca gtggagaata ccaactggtc
   101761 gcaatctatt ctagaaaact agaaactgca gcaacctttg cttctcgcta tcagaatatc
   101821 caactattcg atcaattaga agtcttcttc aaatcttctt ttgatttagt ctatatcgcc
   101881 agtccaaact ccttacattt tgctcaggca aaagctgcct tgtctgctgg taaacatgtt
   101941 attcttgaaa agccagctgt cactcaacca caagaatggt ttgatttgat tcaaacagct
   102001 gaaaaaaata actgttttat ctttgaagca gctcgtaatt atcacgagaa agcctttact
   102061 actatcaaaa actttttagc agataagcaa gtgttaggag cagatttcaa ctatgccaaa
   102121 tactcttcca agatgcctga cttattggct ggacaaacac caaatgtctt ttcagaccgt
   102181 tttgctggtg gagccctcat ggatttgggg atttatcccc tctatgctgc tgttcgtctt
   102241 tttgaaaaag ctaatgacgc gacttaccat gctcaacagc ttgacaatag cattgaccta
   102301 aatggagatg gtatcctctt ctacccagac tatcaagttc acatcaaggc tggaaaaaac
   102361 atcacttcca atcttccttg cgagatttat acaacagatg gaaccttgac tctcaacacg
   102421 attgagcata ttcgctcagc tatttttacc gaccaccaag gaaatcaagt ccagcttcct
   102481 atccaacagg ctcctcatac gatgactgag gaagtcgctg catttgcaca catgatccag
   102541 caaccagatc tgaatctcta ccaaacttgg ctgtatgatg caggctctgt tcatgagcta
   102601 ctatatacca tgcgccagac tgctggcatt aaatttgagg cagaaaaatg aaaaccaaac
   102661 taccgactga atggcaagaa ctgagtgacc aactcggttt ccaagaattc acccccattc
   102721 aaactcaact atttgagccc cttcttgctg gagaaaacct cctaggagtg agccaaaccg
   102781 gaactggtaa gaccctagcg tatctcctac caagtcttct cagactacaa aagaaaaaag
   102841 cccaacaact cttgattcta gcaccaaaca cggaacttgc tggacagatt tttgatgtat
   102901 gtaaaacgtg ggcagaagct atcggattga ctgctcaact cttcctttca ggttcaagtc
   102961 agaaacgaca aattgaacgt cttaaaaagg ggccagaaat tctgattgga actcctggcc
   103021 gtatctttga actcattaaa cttaaaaaaa tcaagatgat gaatgtggaa accatcatcc
   103081 tggatgaatt tgaccaatta ctagatgatt ctcagattca ctttgtagag aaaatcactc
   103141 actacgcacc tcgtgaccac caactggtct acatgagtgc cacgaccaag tttgaccaag
   103201 aaaagattgt gccgaataca cgcactattg atctctctga tcaaaaattg gacaatatcc
   103261 agcatttcta catgcaggta gaccaacgtc atcgagtgga tatgctacga aaactggctc
   103321 atgtagagga tttccgtggt ctagtcttct tcaatagcct gtcagacctt gggaatgccg
   103381 aggaaaaact acagtatcgt gatatattgg ctgtttccct cgctagtgat gttaatgtta
   103441 aatttagaaa aatcatctta gaaaagttta aagataacca actaaccctg cttcttgcaa
   103501 ctgacctttt ggctcgtggg attgatatcg atagcctaga atgtgtcgta aactttgata
   103561 ttcctagaga tagcgaaacc tacacacacc gtgctggccg tactggtcgt atgggcaagg
   103621 aaggttatgt tatcactctc gtcactcatc cagaagaaat caaaaaactt aaaaagtttg
   103681 caagtatccg agaaattgtc ctaaaaaacc aagaactcta tatcaaataa agccccattg
   103741 ctctatacac atccagtgta tggagagctt ttttataagc aattcaattt tatactcatc
   103801 tgctttcaaa aagcattcta gtccatctcc gattaacgat gaactttatc acctccttct
   103861 ccaatccttg tatgacatct tgaagttgat tcatgacatc ttccaaaatt cgaaaggctt
   103921 tattcttaaa tccacgttta cgaatctctt tccacacttg ttcaatgggg ttcatctctg
   103981 gtgtgtatgg aggaataaat gcaaaaccaa tattagtcgg aatctttaag atacttgatt
   104041 tatgccatgt agcattgtcc ataacgagta aaaaataatc atctggataa gcttgtgaaa
   104101 gctcttctaa aaaggcgttc attcactcag tattacatct accagctatt aagaaaaatg
   104161 attcgcctgt atgggtccat aacaatagcg aaattctcgt atatagtgac tatggatatg
   104221 tggacctact cctattggag cccaacaaga tcccagttta ctgattctac cgaaaccagc
   104281 ctcatcttgg tacatcaagc gaaccttatg aaaaggtcta ctggttttaa agcgctttct
   104341 tgtcttcttg aattgagatt ttatttttag atgcgacaat ggtttgagcg tctgctttcc
   104401 taggatgttc tggacgtggc gtaatatttc gccaaccatg gcgcttcaac aattgataga
   104461 aggcatcacg tgtgtaggaa cgacctaact cctttttata agcctgaaat aaggcatcaa
   104521 ttgtaacaaa ttctcctgcc tctgcagcct tcaaatggcg agcaagaaag gctttctctt
   104581 cctcaactgt catatatgca tggttacgac caccacgtgt ttcttgaagg agagagtcga
   104641 gtccgaactc ctcatatttt tttacatttc gccaaatcat tgtttgatta cagtctaaaa
   104701 gttctataat ctctttataa gatttgccca tatcaaacga aatagaacgt tttgaagacg
   104761 tttatgatat ttagctgtac gagagtcttt taaaagtgtt ttgatggttt ggatttcttc
   104821 tttaattgat ttcatattac tattgtataa tgctttttga ttttagttta gtattatact
   104881 cttcgaaaat ctcttcaaac cgcgtcagct tcgccttgtc gtatagatgt tactgacttc
   104941 gtcagttcta tctacaacct aaaaacagtg ttttgagcag tctgtagcta actttctata
   105001 gtaaaatgaa ataagaacaa gacaaatcga tcaggacagt caaattgatt tctaacaatg
   105061 ttttagaagt agatgtgtac tattctagtt tcaatctatt atagtttatt ctttgatttt
   105121 cattgagtat tagttcaata tctaaaaaaa gaaccttgcc aagcaagatt cttttagtgt
   105181 ctgacttaaa taattgttct tctgggaact aaatcgaatt aagcttcgat ttctgtaacc
   105241 atacctgaac caacagtacg tccaccctca cggatagaga atgtagtacc ttgttctacg
   105301 gcgattgggt gaatcaactc aacgtcgatt gtcacgttat caccaggcat taccatttca
   105361 gtacctgctg gaagttcgat tgaacctgta acgtcagtag tacggaagta gaattgtgga
   105421 cggtagttgt tgaagaatgg agtgtgacgt ccaccttctt ctttagtaag gatgtagact
   105481 tcacctttga atttagtgtg tgggttgatt gaacctggtt tagcgataac ttgtccacgt
   105541 tcgatttcat cacgttgaac accacgaaga aggacaccta cgttatctcc agcaagacct
   105601 tcgtcaagtt gtttacggaa catttcaaca ccagtaacaa ctgctttttg agtttcttct
   105661 ttgataccaa cgatttcgat ttcgtcgttg actttaacga taccacggtc tatacgtcct
   105721 gaagcaactg taccacgtcc agtgattgag aatacatcct cgactggaag aagcaatggt
   105781 ttgtcagtgt cacgttctgg ttctgggata tactcatcaa ctgtgttcat caattccata
   105841 acgatgtctt cgtatttaga gtcaccttca agagctttaa gtgctgaacc ttggataact
   105901 ggaagatcgt cacctgggaa gtcgtattct gacaataggt cacggatttc catttcaacc
   105961 aattcaagca attcttcgtc gtcaaccaag tcaactttgt tcatgaagac gataaggtgt
   106021 ttaacaccaa cctgacgtga aagaaggatg tgctcacgag tttgtggcat tggtccgtca
   106081 gttgaagcta ctacaaggat agctccgtcc atttgagcag caccagtgat catgttttta
   106141 acgtagtccg cgtgtcctgg agcgtcgatg tgagcgtagt gacgtttttc agtttcgtac
   106201 tcaacgtgcg cagtgttgat agtgataccg cgttcgcgtt cttctggagc agcatcgata
   106261 gacgcatagt ctttaggttg gttaactgat gaaggcaagc gacgtgccaa aacagttgtg
   106321 atagctgcag ttagggtagt tttaccgtgg tcaacgtgtc cgatagtacc aatgttaacg
   106381 tgtggtttac tacgatcgta tttttctttt gccatttgag taaaagcctc caataaaata
   106441 tattttatag atagacagta ggcaatacag tctaactttc cttactattt tatcaaattt
   106501 cagctaaatt gcaagtgttt tacaatgttt ttgtgaatta ttcttggtaa aaatttaact
   106561 aattaataga aagtactaaa tagacttatc cttcaaggag ttttcagcat tatccatcca
   106621 ctcacttgct gaaaatgtaa acagtctctg gtttatatag taaaatgaaa caagaatagg
   106681 gcaaatcgat caggacagtc aaatcgattt ctaacaatgt tttagaagtt gaggtgtact
   106741 attctagttt caatctacta tacaacctca aaactgtgtt ttgaacaacc tgcggctagc
   106801 ttcttagttt gccctttgat tttcattgag tataaaattg cagataaaac gataacaatc
   106861 ataggactca gcagagtcaa tgtaggtcga agaatagccc tcctaatcgc ttattttata
   106921 gcaaaatgaa atagaaactg aacattttgt tgaggaaggt aaatcgattc ctcacaatgt
   106981 ttgagaaaga agggaggact attccaactt caacccacta taaagcagac ttacaagata
   107041 gggaacccat ctccgataat atatagtaga atgaaaactg cacaatttga ttggagaatt
   107101 caaaccaatt tctaacaatg ttttagaaac aagggtctat tatttcaact gcaacctact
   107161 atagcccatt gaagctggaa tagcccactg aaacttctaa accactgctg gagaggagtt
   107221 tgtttagagt ttctttcatt tccctaaaaa atcaaaaaga gagaaccagt ctgatcctct
   107281 cttacttata gatggtgctc actcaaatgt taaaggagct atttcttaga gataaaggaa
   107341 tttgaataca gctactgccg caattgctgc tgcgataggt gctactactg gtacccaaga
   107401 ataccaccat tttgaatcgc ctttatgctc accaagaact gattttggaa ggaaagcatg
   107461 aaggagacgt ggtcccaagt cacgggctgg gttcaaggca ggtcctgtag gtcctccaag
   107521 tgatgttacc aaagccataa cgaggaatcc aagtgccaag tgagccacag aaagtcctga
   107581 agcagtgtgt ggagccacct gtgctttaat agccaagtca gaaaaatcaa ctgtttgtcc
   107641 tgcttctatt gccttttgtt tcatgaattg aagcacttca gcaccaaaga agtttttagt
   107701 caaaccaaga gctgcaaaga acaaaacaaa tgaaccaaca aactcattaa tcaaaccatt
   107761 gacagttgct gcatagcgac tttcttttgt accatggtca atacttgaaa tagttgagaa
   107821 agttcccaag atgttatttg gtttttcagt tttcaagtag aatggacggt atgttgccac
   107881 aactaaggct tggccaaaga tagcccccaa gacttgcgcg ataatgtaag gtaccacttg
   107941 tgcccaaggg aaaagaccgc taactgcaag ccctagagtg aaagcagggt tgatgtgatt
   108001 cccagatacg ttaccaaaca tcaaggctgg gatcataacc cccataccat aaccaacagc
   108061 gatgacgatc cagccacttt ggtgaccttt tgtaccttta agttcaacgt tggcaactgc
   108121 accattccca agaatgatca aaatggcagt tcccaaaaat tcagtggcat acttcagtgc
   108181 ccatgtgaaa tccatttgct agattctcct taaaattttt tagatattcc ttattttatc
   108241 aatttttacc ctatttagca actgatttct ggaaatattt ttaaaaaaat aggattcata
   108301 gtttcccagt ccaacgtact tgtaagcgtt tttattcttc acgaaagacc tcgttctcaa
   108361 aaccaggaaa aaagcccaca tctgtgagct tttcctggtt cctagattct aaaatctatt
   108421 atttttcatc ttcttttttc ttgaagaatc ctaatactag actagctaac aaggtcatga
   108481 taccagcact agccaaggta gcattagctt ctgtacctgt gtttggcaat tcctctctct
   108541 tacctgtctc ataagtcgga acttctgggt ctggattcac tggagtttca gtttttggag
   108601 tacctggttc tggagttggc tctggtattg gagtctcttg atttggtagt tctgggtttg
   108661 gtgtcggaac acttggatgc tctggatttg gttgtgggat tggtttttct ggagtcggtt
   108721 cacctggagt acctggttcc tgaggacttg gaatttctgg tttttctgga gttggtttat
   108781 ctggtgttga taaacggtca taccttaccg ttatttcttt atcactagag tctgacgtaa
   108841 cttcttgtga ttcaactgtt ggaatatctg gatctttgta cttgtcaatc ttaccagata
   108901 taacctcgtc ccagtttcct gttgtccatt caccgtaggt tacaactccc gtgaccttgt
   108961 tctcagtttt tgtacggctt aaggttacag gttgaacaac atcttctttt acattttggt
   109021 tcgtaacttt atcaacgtaa tgaatgatac gcgttatagt cttcgtctca gtagaggttg
   109081 ctgttttgga aaccactgtt tcctcaacat tctcacggta gtaatagtca actgttgcac
   109141 cgtcttctgg tacgcatttg caggagttgc taccaaggtg tatgttgttt tccttgtgat
   109201 aactcggtct tctttgtcct cagttgttgt tttcccttca atagtttttg attctgtggt
   109261 atactcagaa cctatcgcta aatcagcttt tataacagac tctgccaact tctcttggct
   109321 accttcttta tagtaattgg ctgttactgt agcagtggtt ggcgcttcgc tttctctata
   109381 aactaaggtc actgttctac cttcgcttac aatattccca gttaaacttg cagaatttgt
   109441 atctgcttct ttaaaagtat aatattttcc gtcagtagta gtcatgctac tgagtttttt
   109501 atctgtgaca ttatagctgg taccaatcag ttgtttttta ttggtaatgt aagttccgtc
   109561 actttctttt tctccaattc cagtatcatt tttcaatgat agcaaacgcc cttgttcatc
   109621 aacatagcga actttcacat tttctgagat tagttctgcc aattctgagg tttttttctt
   109681 tttctcttct tcgggaatat ttagttttgg aatgattttt tcaacaacgg ttcgtgatgg
   109741 ttccacaata tcttggatga ctgaaaagtc agctagaatt gggagattat actgaacacg
   109801 gtgactttga gtgtttactc ctactctttc attattctct gaaaatactt gtacggtata
   109861 agaaacaaca tcttttccta atagaacatc cccagtagag aaatagccgc cttttcctag
   109921 tttgctatct ccagagtcca cttctttcct aatcttatca gatagttttt taccagtcag
   109981 tacattcgtt cgcacaatcc ctttgtctac ccctacaaag tgggagaact ttttgaactc
   110041 ttcagaacca gatctagccc aaccattatt aagggcattt gcttttgtat ttgtattctc
   110101 tctcaaaggt ttggcgatta gaattatatt catcggcact tagagttgct gctatatctg
   110161 actcttgaat accaacttcc ttactaccat ttctagcggc agtatatgtg tatttatctg
   110221 tttctacttc tagctgatta tccttaacat gataggtaat tttctcctgg tataagagtc
   110281 ttcagtagtt tatatgctct gtcatcatct ttagctttag aagcagctga gtttagccaa
   110341 attggggtat taggagtatc tttatcagcc tgtttcaaga cattattcaa gtcatttgct
   110401 aacctattgg ttgtcctcac tgtgaaagtt ttcttccagt ctgaaccact tttattagac
   110461 ttagatatgc tcatgaaatc ctggtcaaca ttcaacacaa tatcgccttg ttttttagca
   110521 tcttccgttg cttctgcttc aaattgatca tggagttttt gttgctctgg tgtatagttt
   110581 ttttatttac acgatttaat gtactatttt ttattttagt attaagaact ccattaatac
   110641 gatttttaaa ttctgcttca aaaaatccct taatttgttg gtgcgcaagt tcaacattca
   110701 aacctttctt atacaagtct tcattctgaa cgatttcggc tacacggtga atggtttgat
   110761 cgtataccgt cttctcttaa ccagcagtat ccttagtttt aatgactact cgataggttc
   110821 ctttagaacc gttatagtca tctagtttta aaaaagcatt ccaaacattc aaaaatagtt
   110881 ggaacttccc ttaataaatc cgtcactttc tttttcaaga tagcccaagc ttgctcaata
   110941 ggattcaaat ccggtgaata aggtggtaga ggtaagaaaa agtgtttatc ttggatgcag
   111001 agttcatcca aaatgttctt gggatgaaaa ctagcattgc ccatgacaat aacatgaggt
   111061 gtcttcaaag caggtaggag ttgcgttttg aaccactcca caaagaaatc gcttgtcatg
   111121 cttttcttgt aaatcatggg agctataaac tctccgtcta cttgtcctgc aacaattgaa
   111181 gttcgctcaa aacgacgtcc gctaatcttt tcatagactt tctcccctct aggagcccct
   111241 gcataaggac gatagaggta gcggtcgatt cctgtttcgt caatatatac gattggtaaa
   111301 tcttttaggt tatccaaaat atcaagaaac tcagcgactt tctctggctc ttgttcctta
   111361 aagctcgtca tcttttttta aagtgacctt aatctgcttt aaagctgccc atactgaagg
   111421 aacagcacaa tcaaaatgtg ccgcaatttc ccgtaaaaaa gcatctggat gagcctctac
   111481 aaaggctttc aattcctcta aaggaatctt tcggtttttg acgactcgct ttttcctctc
   111541 tatgtgtcct tgttcacatc tttcttttcc cacgtgaaga gagttctgac gccaacacca
   111601 aaaaacttgg ctgcctcgac atggctgtgc ccctctttga tgtaatctaa tgctcgctgt
   111661 ttaaaatcag tactatatgc catagcttta ttataatatg cttgtttaaa actaagcaac
   111721 tatatcaatg ttttgttatt agaagactta ctttttttac tgaaatcgaa tttttcctaa
   111781 cctcaacatc atataacccc aaaattcaat ctgacctggt ttgaagagat gttcgaagca
   111841 gataaggttt tactaaaact aaaaaaaatg atataatcaa actgattaaa tgttttaaaa
   111901 ataaaggaga atttgaatgt cttaccaaga aaattaccag aaatgggttg attttgtgga
   111961 gcttcctgac taccttcgtc aagatttgga aaatatggac gaaaaaacta aggaagatgc
   112021 cttctataca aatcttgaat ttggtactgc aggtatgcgt ggcttggttg gtgctggtac
   112081 aaaccgtatc aacatctacg ttgttcgcca agctactgaa ggattggctc gtttgattga
   112141 gtcaaaaggt ggaaacgaga aagaacgcgg tgtagcaatt gcctacgata gccgtcactt
   112201 ctcacctgag tttgcctttg aatctgcggc agttcttgct aaacacggca tcaaatctta
   112261 cgtatttgaa agccttcgtc caactccaga actatcattt gcagttcgtc atctcaactg
   112321 tttcgcaggt atcatggtca cagccagcca caaccctgct ccatttaacg gttacaaggt
   112381 ttacggtgaa gacggtggac aaatgcctcc acacgatgcg gacgctttga ctacttatat
   112441 ccgtgcaatc gaaaacccat ttgcagttga agttgctgat gtggaaactg aaaaagcttc
   112501 tggcttgatt gaagttatcg gcgaagctgt tgacatagaa taccttaaag aggttaagga
   112561 cataaacatc aacccagcct tgattgaaga atttggtaaa gacatgaaga ttgtctacac
   112621 accacttcat ggtactggtg aaatgttggc tcgtcgtgct cttgcccaag caggatttga
   112681 ctctgttcaa gttgttgaag cgcaagcaac tgctgaccca gacttctcaa ctgtaacatc
   112741 tccaaaccca gaaagccaag cagcctttgc ccttgctgaa aaacttggtc gtcaagttgg
   112801 tgcagatgtt cttgtcgcaa ctgacccaga cgctgaccgt gttggtgttg aagttcttca
   112861 aaaagatggt agctacctca acctttcagg taaccaaatc ggtgctatca tggctaaata
   112921 catcttggaa gctcacaaaa acgctggaac tcttcctgaa aatgccgctc tctgcaaatc
   112981 tatcgtttca actgacttgg taacgaagat tgctgaaagc tacggcgcaa ctatgttcaa
   113041 cgtcttgaca ggtttcaaat ttatcgctga aaaaatccaa gaattcgaag aaaaacacaa
   113101 ccacacttac atgatgggat ttgaagaaag cttcggttac ttgattaaac catttgtacg
   113161 tgataaagat gccatccaag ccgttcttgt cgttgctgaa cttgctgcct actaccgttc
   113221 tcgtggtttg acacttgctg acggtatcga agaaatctat aaagaatatg gctactacgc
   113281 agaaaaaaca atctctgtta ctctttcagg tgtcgatggt gctgaacaaa tcaaagcgat
   113341 tatggctaaa ttccgcaaca atgctccaaa agaatggaac gaaacagcta tcactgtcgt
   113401 agaagacttc aaggcacaaa ctgctactgt tgctgacggt actgttacaa acttgacaac
   113461 tcctccaagt gatgtgttga aatacacact tgctgacggt tcatggattg ccgttcgccc
   113521 ttcaggtaca gaaccaaaaa tcaagttcta cattgcagtt gtaggggaaa ccaacgaaga
   113581 atcacaagct aagattgcta acatcgaagc agaaatcaat gcatttgtaa aataaagacc
   113641 tataaaagat gagaccaacc aacctcatct tttttcgtat caaatctaag caattttaga
   113701 aactttatgg catactagac ttatcaatga aagcgaggta atctcatgga acaattttta
   113761 gataacatca aagaccttga agtcactaca gttgtgcgtg cgcaagaagc tcttgataaa
   113821 aaagaaactg caaccttctt tatcggtcgc aaaacttgcc cttactgccg taaatttgca
   113881 gatacattgt caggtgtcgt agctgaaacc aaagctcaca tttacttcat caatagtgaa
   113941 gaaccaagcc aactcaatga tttgcaagca ttccgctcac gctatggaat cccaactgta
   114001 ccaggttttg ttcatattac agatggacaa atcaacgtcc gttgcgactc ttcaatgtca
   114061 gcacaagaaa tcaaagattt cgcaggattg taaaaaatca gctaacaagt cttaaaatca
   114121 caaaaacgca taatgtaagg tgcaaaaacc ttgatattat gcgttttatt gttcctgaaa
   114181 cagttacatc agcatttcat tacagaacat tttaattttg gaagtcaaat caatttttaa
   114241 caatgtttta gaaatcacag tgggctattc catattcaat tatccagatt caatcgctat
   114301 tatcgttttc ctagattaca aaaaaaacta cgttttgcta atcaaaacgt agtctcagcc
   114361 actattttat cttactgtcc ttcttttact tctttggttg ctacatcttc tccaaaccat
   114421 ttttggctga tttcttggaa cttgccgtcc ttgtaaagac tagaaaaagc ttcatttatc
   114481 ttcttaacca aggttgtatc ttccttacgg gctccaaccg caaaagcttc tgtttctagt
   114541 ccaactgtaa agacattata atcgtttaaa acaccttctg cttctaaata atagtttgca
   114601 tagacacggt caatcaatag accatcaatt cgatcgtttt tcaaatcaat caaggcttca
   114661 ttaaaggttt ggtattgatt cgcttcctta ttagcgacaa tattcttcaa aatttctgga
   114721 tttgcttcaa agtccgcata accagatgaa ccagcttgag ctcctaatgt ctttccagtc
   114781 atatcctttg cagtcgtgat accagatgat ttcttcgtaa ccaatacctg ctcattcttc
   114841 atatatgagt tactgaaagc caccttttca cggcgttcgt ctgtagcgga atagccattc
   114901 caaatcagat caatcgttcc ttttgtcaat tcagcttctt tcaaatccca atcaatcggt
   114961 tgccaattta ccgtgattcc gtatttttca aaaacagctg tagctaaatc aatatcaaat
   115021 cctgcataag aaccatcttt ctgagcaaat cccattggaa caaaagtact atcaaatcca
   115081 atagtaatag acttgttaga ctggtacttt gaccaattat ctccactagt ttcgctagaa
   115141 tttttcccac aagctactaa gaacaaagca gtcatcagac tgactaatac aagcatccat
   115201 tttttcatcc atttttcctc ctatttaggt tctactttca ataatacatc tgcgatattt
   115261 tcagcaaact gcaaatcatg ggtaaccaca atctgggtca tcccaagttc cctattttgc
   115321 aagattagct tctccacttc caaacgtaat tctggatcca gggcagaagt tggttcatcg
   115381 tagccaatga tttctgggtc aatcatcata gcacgcgcca aagccacccg ctgcttttgc
   115441 ccaccagata gtgagaaagg ataggcctct gcgtgtcctc ctagtcctaa ctgttccaag
   115501 agtccactcg ccttcttctc agcctcttcc tgcttcattc ccatggtctt cacaggcgat
   115561 aaagtcaaat tttccagaac tgatagatga ggaaatagtt gaaaatcttg gaatacaaat
   115621 cccagtagat tgcgcttctg caattcatcc agctctaaag gttgtccatt ataaaagatt
   115681 tgccctgaat caatggtttc aagacctgca agcatacgta aaagagttgt cttacctcca
   115741 ccagaaggtc caacgatagc caggatttgc ttttcaggaa tacttagact gaaattagac
   115801 aggatttgtt tgtctccaaa gactttattg atatttcgta attctaacat ggcagcctcc
   115861 tatctataat aactgtactt tttctcaact tttttggaaa taattgtcac aatcccaatc
   115921 aaaatcaaat aaatggctcc tgccaagaac ataggaacta gactagcatc gcggttagca
   115981 gctgttcgac tagccaagat aaggtctgaa attccgagag catagaccaa agaagtatcc
   116041 ttgaccaaac tcataacttc attaaagaca ctaggaagaa cgatcttggt cacttggggc
   116101 aagataatat agcgcactct gtcaaaaggg ctaaacttca agaccttggc ggcctcatac
   116161 tgtcctcttg gaatagtgtc aattccccca cggaaaattt ctgcaaagta agctgcatag
   116221 ttgagaacaa aggcaataat agctgcagga aggcggtcta aacgaatccc aatacttggg
   116281 agcacataat agataaaaat cagttgcaag agtaaggggg ttcctcgcat aacccagatg
   116341 taaatgttaa tcagataatg gaggggcttc caatggactt gcaaggcaaa agcaatcaaa
   116401 acgcccaagg gaatcgaaaa tagcaagacc agtgcaaaga cctgtacagt cgtgctcgca
   116461 ccattcagta aactcggtaa tatctcaaat aaataagaca tactgcacct cctaaaagta
   116521 attgttccta ttatagcatg aataaacaag attaccaagt atttttgtaa aaagattcta
   116581 ccatatacaa ataaaaaccg tagctatcaa aagagataaa ctacagttct atatgtttaa
   116641 acattcttac aatctctcaa acagttcttg catttgcaca tcatctggaa ccagttttaa
   116701 gtaagtgtga gcatggactt ttgcttcttc aaaatgtccc aattcacgca agagatagat
   116761 atagtgttcc agaaattctg gattgtcctt caaatctcct gtcaactctt gataatgctc
   116821 ataagcagta tccaaatcgt ccatttcttg ataagaacga gcaatcatcc acttggtcaa
   116881 aagattttct ggctcctcac tctgcaagtc tagaatatcc tcataacgct cctgctccag
   116941 ataaatagtg gctaaacgaa gcaagatttc ttctgtatcc tcagcgtctt cttttgcagt
   117001 aaggagataa ttttctgcac cactagcatc atgcaattca taagaaaatt gtgaagcagc
   117061 tagcaagagg cgagtttcaa agggattttt ctctaatcct tgcttagcga tacgcagggc
   117121 ttcttgaact tgatgttcct tatgtaaagc ctgactgtac ccatactcat agccttcaaa
   117181 gtcaggagaa atggtatcaa gctgcttaaa gtagagggtg gctttttgat attcttcttg
   117241 atcaaaataa agactggcca actcaaaagc tgttaagtca tcgtattcta actccagggc
   117301 tttttctaaa aactcagtag ccgtttcaaa tttccctaac tgagcatagg caaagccaat
   117361 tcgttgatag gtggaaatgc ccgtttgctc ataaatcgag cgattatcta actgggcata
   117421 ggcttgaata gccgcttggt aattttccaa ctcactatcc aactctgcca aacccaatat
   117481 caagagagaa tcctctgagt aggtcaaggc ctccaataat ttctcacgtg ccacatctgt
   117541 caaaccttcc agctggtaaa ggtctgcctt caaaaccaaa gacgagacat accagtcact
   117601 gtcagcttgg atttcctcaa gataggtaaa ggcttcttct atttgaccat cctcgctagc
   117661 aattgcagct agattaagat gaacctctgg aaaatcctct acaattttca ggtaaatttc
   117721 cttggcctga ggatagaaac caatcccttc aagataagtt gccaactcat acagaagatc
   117781 acttgaatca ttttctaaag ctttggcgaa ataatgctca gccttagtta aatcttgctc
   117841 ctccaaagcc tgtaacatct gttgactatt gttcactctt gacttcctca ccctctaatt
   117901 catatagacc actgactacc ttataccatt cgaaaatggc tgaaatgaca accttagcag
   117961 aggcataaac cggaatacca agtaaaactc cccagatacc aaacatagat cctgaagtta
   118021 acaaaacaaa gagaacatta ataggatgga tgtttaattg acttcccaaa atcaatggag
   118081 agacaaaacg gccttcaata gtttgttcta caataaagac aatcactact ttcaaaagca
   118141 tgactggacc agcaatcaaa cccaatacta gggcaggaag catggctaga aagctaccaa
   118201 gataagggac cagatttaaa ataccagcag taacccccag cgtaaccgca tagcgtagac
   118261 caataatctt gaagaagatg ataaacatta ctgctacaat aatagccact gtcacttgcc
   118321 ctcgaacata gttggacaac tgttgattca catctgatag aacttgtcca acaggttcct
   118381 tcaattttct tggaatgaat tgggtcaaat agttacgcaa gcctttccca tcacgcaaga
   118441 gataaaagag catgaaagga acgataatca aggcaacaat cacttgagaa gctccgctaa
   118501 taaaggcact cacccagttg actgcctgag atgaaacctt acttgccaaa actgtagcct
   118561 ggctagaaaa attggtcaaa acttgctcta attgaggtct gaaatcatct ggcaggtgct
   118621 gggctaccaa tccattaaca atcctatcta tatcttctaa gtaaacagga acgtttcttg
   118681 caaaggtcaa aacctgacgt tgcagatttg gaatggcgac tgccaagccc caaatgataa
   118741 agagagcgat gataacaaag acaatagtga tagctataac acgattaatc ttatgcttct
   118801 ccatccaatc aacaatagga ttcaacaaat aatataacaa accagacaaa atgactggca
   118861 acatcacaac tgctataaag tctaaaacag gtgaaaatag aaaactaatc ttacttaaaa
   118921 taaaaagatt caatcccaat aataaggtta ctaaaaatac cgtaattgcc ttgttatcta
   118981 aaaaccactt gaaaaaccaa gataggctaa aatgtttctc tttttgctcc ataaatactt
   119041 cctttctatt gttctctcat tataccattt ttgaaacaaa ataactcttt tttaaagtgc
   119101 ttacatctaa ttggatatct ttaatttact tgtttttgtg atataatagt cttatcttta
   119161 cacagaggta tagtaatgaa agaaactgtt tattttggaa cttatacacg tcgtacttct
   119221 caagggattt acaaggcaga ctttgataca gaaactggtc agctttcaaa tctagaactt
   119281 tttgcagctg agccaagtcc aacctacctt gcctttgacc agcaccaaca tttatacact
   119341 gttggtagcc aagacgataa ggggggaatt gcagcctatc aaactgacgg gactgtgtta
   119401 aatcatgttg ttgaagaagg agctccccac tgttatgttg ctgtcgatga aaagcgtgat
   119461 tcggtttacg cagccaacta tcacaaggga caagtccttg tttataaacg ccaggaagat
   119521 ggtagtcttc tacttagtga tatggatcaa cacagtggcc aaggtccaca tgaaaatcaa
   119581 gcttcccccc atgttcacta tacagattta acacctgacc actatctagt gacctgcgac
   119641 ttgggaactg accaagtcat cacctatgac ctcgatcaag aaggaaaatt atctaagctc
   119701 tatacctatc acagcaagcc aggagcaggc tcacgccata tcattttcca taaccactat
   119761 aaaatcgctt atctcatttg tgaactcaat agtactatcg aagttttaat ctacgatggc
   119821 gttggcgaat ttgaacgtat gcaggttatt tcaactttac cagaagctta cgaaggcttt
   119881 aatggaaccg ctgctattca tctctctaaa gacggtaaat acctctacgc ttctaaccgt
   119941 ggccatgatt ctatcgcagt atataccatc cttgcggacg gtagcttaga gttattagaa
   120001 atcgttccaa cgcatggtca gactccacgt gattttgatt tgacacccga ccaaaaattt
   120061 ctcattgttg tccatcaaga ctctgacaat gcaactgtct ttaaacgtaa ttgtgacaat
   120121 ggtcgtctag cagaactctc caacgacttc catgttcccg aagcagtctg catccgtttt
   120181 gctccttaaa acaccataaa aaatgaactt ggtattttca agttcatttt ttcttatagt
   120241 ctatttccga cattaatacg gttaatagca cgttgcaaag caatcttagc acgacgttct
   120301 tggtcaatca aatgtttgtc ttgtgcttct tcaattgcac gttctgcacg aagtttggca
   120361 cgttctgcac gactgatatc gatatcacga gcacgttctg cagagtcagc gacgattgtg
   120421 atcatatcat tggcaatttc aataacgcca ccgtttactg caatccagtt cacgtgatct
   120481 ttatcatcga tacgttttac ctttacttca tcaactgcta aaaccgcaat catattttca
   120541 tgtcgtggca agatccccat ctcaccatcc agagttcgaa ccgatacata gctggcatgg
   120601 tgatcataga cgagaccatc tggtgtcacg atctggacag ttaactgagc catagatcac
   120661 ctcttaaaat cccatttttt cagcttttgc aatcacatct tcgatagaac ctacaccacg
   120721 gaaggcatct tctggcaagt ggtcgtattt accatcaagg atttccttaa agccacgtac
   120781 agtttcagca actggaacat aagaacctgg ctgaccagta aattgttccg caacgttgaa
   120841 gttttgtgac aagaagaact ggatacgacg ggcgcgagca accaaggtct tttcttcatc
   120901 agaaagctca tccataccaa ggatagcaat gatatcttgc aattcatggt aacgttgaag
   120961 gacacgtttt acttcagcag caactgcata gtgctcttct ccaacgattt caggtgccaa
   121021 ggcacgtgag cttgaagcaa gtgggtcaac ggctgggtag atacccaatt gtaccaactt
   121081 acgttccaag tttgttgttg aatccaagtg agcgaaggct gttgctggcg ctgggtcagt
   121141 atagtcatcc gctggcacat agatagcctg gatagaggtt acagaaccct tcttggttga
   121201 tgtgatacgt tcttgcaatt gacccatttc cgtagcaagt gttggttggt aaccaacggc
   121261 tgatggcata cgacccaaaa gggcagatac ttctgaacca gcctgagtga aacggaagat
   121321 attatcgata aagagaagca cgtcttggcc ttccacatca cggaagtatt cagcgattgt
   121381 caaaccagta agggcaacac gcatacgtgc tcctggtggc tcattcatct gaccaaagac
   121441 catggctgtt ttctcgataa cgcctgattc tttcatttcc cagtaaaggt cattcccctc
   121501 acgagtacgt tccccaacac cagtaaatac tgaaatacca ccgtgctctt gggcaatgtt
   121561 gtgaatcaat tcttggatta agacggtttt accaactccg gcaccaccga aaagtccaac
   121621 tttaccacct ttaaggtaag gggcaagaag gtcaataacc ttgatccctg tttcaaggat
   121681 ttcagaagag gtagacaact catcaaaagt tggagctttt ttatgaattg gctgacgctc
   121741 tgcgtcttct gtaaaaggag cttccaaatc aatggtatct cccaaaacgt tgaagacacg
   121801 tcccaaagtt tctttaccta ctggtacaga gattggacga cctgtgtcca atacttccat
   121861 tccacgagtc aacccatctg ttgattccat ggcgatagta cgaaccatac catctcctaa
   121921 ctccaaggct acttcaagga cgatttttgt ttttctttcg tcatttttgt agacgacaag
   121981 tgcattgtta atctcaggaa gtttttcccc tgctgcaaac aaaacgtcta caacgggacc
   122041 gataacctga gcaattttac ctgaactcat ctccttctcc tattctatat aagatactgt
   122101 cggttcctag ctcaactagg tcctaagttc attttcatac gagctggact agagcctatt
   122161 ctaaggcact agcacctgct acgatttctg taatttcttg tgtaatcgcc gcctgtctgg
   122221 cacggttata ctgaattgtc aaatcattga tgactttctt agcattatct gtcgctgttt
   122281 gcatggctgt catacccgca gcattctcag ctgtcttggc atcgataatg gcaccgtaaa
   122341 tcatactttc tgcaaactga ggcaacaact gctccagaat ttcttctcgg ctggtttcca
   122401 attcaaaagt caagctgtac tcttcatccg cttcatttgg atccaagtca acaatcggaa
   122461 gcatttgttc cacacgcatt tgactggtta gcgtattgac atggtggttg tagcaaacat
   122521 aaagctcatc aaagagttca ttttggtaca tttcaacagt ttttgaaata atcttacgaa
   122581 cttgatcaaa gctaggttgg tctgccaagc cacgtaattc ataaagtggt tgaataccgc
   122641 gagccttaaa gaaatcagct cccatcccac cgatacagat catttcaaaa cctttaccgt
   122701 ctgggtggta ttcttctttc aactccataa cagctttcaa aatagaggaa ttataacctc
   122761 caaccaaacc gcggtctgaa gtgataacga tatagcctgt cttcttcaca gaacggctaa
   122821 tcaacatcgg attagttgaa gcaccagctc cattaccatg aaggatatct gtcaaaagtt
   122881 tacgcacttt ctgagcgtaa acttggaagt tgcgagcagc ttcttcagag cgacctaact
   122941 tagcagccga taccatttgc atggcattag tgatttgact cgtatttttt gttgaggcga
   123001 tttttgtttt aatatcattt agagacactg ccatctgaca cctctattct tattggaagc
   123061 tagattgatt gagaaactct gtaatcgcag catccaagac tgcttcttct ggcaagtctt
   123121 ttgtatcacg aatggtttcc aaaatctctg gatgttgagc atcaaagaag gcatggaact
   123181 cttcctcgaa acgaacaata tcatctactg gaacagtatc caagaaacca tgtgtcaaag
   123241 cataaagaat ggttacttgt ttctcaacag gtaatggttt gtgaacaggt tgtttcaaga
   123301 cctcaacggt acgacgtcca cggttcaact tagcctgtgt tgctgcgtcc aagtcagaac
   123361 caaacttagt aaaggcttcc aactcacggt atgaagcaag gtcgatacga agtgtaccag
   123421 caaccttctt catggctttg atttgtgcag aaccacctac acgagataca gatgaacccg
   123481 catcgatggc tggacgaata cctgcattga agaggccatc gccaaggaag atttgtccat
   123541 cagtgataga aatcacgttg gttgcgatat aggctgagat atctcctgct tgtgtctcga
   123601 taaatggtag ggctgtaatt gatccaccac caagttcatc agaaacttta gctgagcgct
   123661 caagcaaacg gctgtggaga tagaaaacat cccctgggaa ggcttcacga cctggaggac
   123721 gacgaagcaa gagcgatagt tcacgataag ctaccgcttg ttttgataga tcatcgtata
   123781 caatcaaaac atgcttacct tgatacataa attcttccgc catagcaacc ccagtataag
   123841 gagctaggaa gagcaatgga gatggttgtg aagcagaggc tgtcacaacg attgtgtagt
   123901 ccaaggcacc gtactgacga agtgtttcta cttgcgtacg aactgttgat tctttttgtc
   123961 caatcgcgac gtagatacag atcatatctt gatctttttg gttcaagatt gtatcaatcg
   124021 caatggttgt tttccctgtc tgacggtcac cgataatcaa ctcacgttga ccacgaccaa
   124081 tcggtacaag ggcgtcaata gctttcaaac cagtttgcaa tggttctgaa acagacttac
   124141 gttgcataac accaggagct ggtgcttcta ctggacgagt tttatcagtg tggatttctc
   124201 caagaccgtc aactggacga ccaagcggat ccacaacacg accaatcaga ctttcaccta
   124261 cagggacttc catgattttc cctgtacggc ggattgtatc gccttcacgg atatctgtaa
   124321 agtcacctag gatgataata ccaacgtctg ttgactccaa gttttgagcc ataccataag
   124381 agccgttttc aaaattcaac aactctccac tcatggcatt ttcaaggcca tgagcacgcg
   124441 cgataccgtc cccgatatag gttacaacac ctgtttcagt cacatcaaaa ttgggtttga
   124501 aattttcaat ttgttgctta attaaagcgc tgatttcttg tgcgttaatt gccaaaagaa
   124561 caccactttc tatttcaaat tttctttaac aactttaagt tgttgtttaa tactcacatc
   124621 aattgtcttg tgattggcaa aaatgacaaa accaccaatg agactttcat cgatttgttc
   124681 ttttacactc cttactttca gagacatttt tttctcaatc aaagggagca aacgagtctt
   124741 ctgttcatca gttagaggat gagcagacgt aatcgtcact tcaaatcgat ttgtttcttt
   124801 ttcaagtcgg ttcaagcaat ctacaagcac atcataaaaa agatttgctc tgtgattgta
   124861 ggccagaacc tggataaagt tttgtaataa aggcgacaca gaatcttgga aaaaagcaat
   124921 tgttttttcc ttatccgact cgtctactgc cacttgtttt aaaaaagaag gcagacctgt
   124981 tttttcaaca acttgcttga tttgagtcaa gtctgaaaag atacggtctt cttctccttt
   125041 ttcaagtacc aattggacaa aaggcatgct gtatttttca attaccttta ctgttttctt
   125101 gtccattaag cttctcctag ctgatcgata tactgatcaa tgagtgcttt atgggcatga
   125161 ctgtcaaggt tttgtgagat gattttacca gctaagctga tggtcaaatc tgcgacctca
   125221 cccttaacac tctgtaaagc ttctacttta ttttgagcaa tttcttgatt ggctttttct
   125281 tttaagtgtc ctgcttctag tttagcatct gctaagatat tagccttact ttgctcagct
   125341 gtttcctttg cattttcaat gattgtctta gcttctttac ggctaccagc caattcatct
   125401 tcgcgttttt gagccaatac ttctgctttt tgacgggctt cttcagctct gtcaatatct
   125461 gaagcaattt tttcagctct ttcttcgaaa atgcctgtaa tattagacca tgcaaatttt
   125521 ttaatcaaga ctagcaaaag aataaaagag ccagtgatta aaataaaatt accaattaat
   125581 tcacctactg ttacgtgcat cagttactcc tttctattcc tcttcaatat taatcttatt
   125641 ccctaaatac acagatgtca aaagagtaaa aacataagct tggatgcagg aaataaagac
   125701 agaaaatgca gtccaagcca aattagctcc aaaggctact ggataccaat aaatagcttg
   125761 gtgggaaaga agaagtaaca aactcgtcat gacctctcct gcaaagatat tcccaaaaat
   125821 ccgcaaagcc aaagataaga agtttgtaaa ttcttccaag atattcatcg gtatgacaaa
   125881 aacaggactc ataaaagatt ttatactttt tttaaatcca cgacgacgaa cgctttctat
   125941 atgtgtcaac aaaatgacaa gaaaagataa ggttaagtca tactgtaaat tagcggttgg
   126001 cgaactccac cagttagtcc catcgatcgt ttgaagcttt gtcattaagc caaggttatt
   126061 ggcaatcacc atgaaaagga ataaacaaag gaaaaagagt gagtaatctt tcatgtagcg
   126121 cgaaccaatg ttaggttctg taaatccaat aacaaagtca tagacatact caagtacatt
   126181 ttgctttcct ttgggtttca aggtcatatt gcggcttgcc caataaataa agacaaaaat
   126241 aactcccaca atcaacaaag tcatggctaa catagtcaga ttgaagataa caggaccaat
   126301 agagatgatt ggattaatac tttcttccat ctaaaatcct cccttttctt ctcgttccat
   126361 gtatttattt gataataaat gagaagacaa gagttacaaa gaaagttcct tcaataaagg
   126421 caacacctaa aaacatcaaa ctacgaaact cagaaagcat atctggttgg cgtgctactg
   126481 atttaaacag tccattcatc aataaacctt caccgacaga tacgcccata caggcaatac
   126541 ataagcctaa aaatgttaaa ttcataacaa attctccttt aaaataaaat ttacttactt
   126601 agtgtagtcc taaaatttaa atttgtcaac ttttaaccgc tattggaagc gtttaataaa
   126661 aattatttcc attttgctaa atttcaagtt caagttagcc atccagaagt cttctctggg
   126721 tgacttgtag tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac
   126781 ttctttggga gtcattttct tggttccctt aggtaaccat ctacgaatga gcctgttgtg
   126841 attctcatta gttccccttt cccaagaggc ataggggtgc gcataataga tgtgctcctc
   126901 agaaaataca tcaaacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat
   126961 cttgtgttgt tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg
   127021 aatcaatcgg atgatctgat gtctactctt tcgatccgtc aagacaagca agcagtagtt
   127081 tttcgctctc gtaagtagaa ccgtatcaat ctcacaatgc ccattctcca agcgaagatt
   127141 gatagcttca ggccgctgtt cgatggattg accagcaggt ttaaagttgg tgctagcctg
   127201 tttcttaagc gcttttcctt ttctagggta aagcagatcc tgtttgctta accccaattt
   127261 ttcatgatga atccaatagt aaatggttga aattcccacg ttaacccctt tagccataac
   127321 catcatttca ggcgaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt
   127381 ggtcaagctt gatttcttga ccgagcgctt gcgattgttt tcataagact gttgagcata
   127441 gtcggcagaa taaacctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg
   127501 cttgatttca gtgtggatag tttgaggaac ttttccaagc agagaggcaa tttctctatt
   127561 tgatttccct tcttttttcc atctttcgat taagcgacgg ctatcgattg tcaaatgttt
   127621 ggcttttgta gtataattgt cttgcatctc tgtgcctttc ttgtgtttgt ggttgaacaa
   127681 caagtataac acagaggtgt tttcttatgc ctacaagagc tttcattatt tccattttct
   127741 ttcagatttc actctattct gaaaaacttg tgtatattta ctgaagctag caagtcttac
   127801 ctgtaaattt aatgaaagca acacaaaatc cgagagggga atctcggatt aatagataga
   127861 gagtttttag tttaaataaa ttgttttaaa atatcaacaa catcacttct tttcttaacc
   127921 tgataagcct tgattcctaa ttttggggct acgattatat tgtcctcaat atcgtctaga
   127981 aagacacaat ttctaggtta taactggtat ttatcgatag ttactcatat acatcagtcc
   128041 acctccatac ttatgtgcga gcctctcttt gtattatacc tccatactca ccttacagat
   128101 tcttttggta ataatatctt tgcctaatgt agagatagtc ttgcaaagaa aaaacttcct
   128161 tgtagccatg tttctgataa aagtccggtg cctggaactg gtaagtattg acaaaggcaa
   128221 aacaacaatt tcgattctta gcttcacttt ctgcctgttg caatagttct gaaccgattc
   128281 cttgccctcg cagttcctct tttacaaaca aatactcgat ttctagccaa tttccaaaag
   128341 tctctgctat caaacctgcc aggagattgc ccttttcatc ttcgacataa agattaagtg
   128401 gctcactttc agcctcttct ctttttgaac ggttatgaac acgaatcaga ttccctattt
   128461 cttgcgattt atgtgattcc ttattttcca atctaaagta tagtgaaatg aaataaaaca
   128521 tgcgcaaatc gattaaggaa tttaatctaa tttctaacaa tgtcttagaa atcaaagtgt
   128581 actattttaa cttcaatgca ctataca
//
LOCUS       DAVDHC010000003       106011 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVDHC010000003 DAVDHC010000000
VERSION     DAVDHC010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 106011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.003"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            68..2899
                     /gene="uvrA"
                     /locus_tag="VUR43_000273"
     CDS             68..2899
                     /gene="uvrA"
                     /locus_tag="VUR43_000273"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET5412022.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            2892..3953
                     /locus_tag="VUR43_000274"
     CDS             2892..3953
                     /locus_tag="VUR43_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET5412023.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            4085..4483
                     /gene="spx"
                     /locus_tag="VUR43_000275"
     CDS             4085..4483
                     /gene="spx"
                     /locus_tag="VUR43_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET5412024.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            4549..5118
                     /locus_tag="VUR43_000276"
     CDS             4549..5118
                     /locus_tag="VUR43_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5412025.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVITKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            5205..5471
                     /locus_tag="VUR43_000277"
     CDS             5205..5471
                     /locus_tag="VUR43_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET5412026.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            5475..5894
                     /gene="ruvX"
                     /locus_tag="VUR43_000278"
     CDS             5475..5894
                     /gene="ruvX"
                     /locus_tag="VUR43_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET5412027.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            5910..6215
                     /locus_tag="VUR43_000279"
     CDS             5910..6215
                     /locus_tag="VUR43_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET5412028.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            6571..7821
                     /locus_tag="VUR43_000280"
     CDS             6571..7821
                     /locus_tag="VUR43_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET5412029.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            7818..8360
                     /locus_tag="VUR43_000281"
     CDS             7818..8360
                     /locus_tag="VUR43_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET5412030.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            8506..10038
                     /gene="cls"
                     /locus_tag="VUR43_000282"
     CDS             8506..10038
                     /gene="cls"
                     /locus_tag="VUR43_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET5412031.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            10116..10259
                     /locus_tag="VUR43_000283"
     CDS             10116..10259
                     /locus_tag="VUR43_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412032.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            10296..11834
                     /locus_tag="VUR43_000284"
     CDS             10296..11834
                     /locus_tag="VUR43_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET5412033.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRGVRRSRRETPVSLWSRFFKGNLYLLVFGLVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDTIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            11954..14161
                     /gene="nrdD"
                     /locus_tag="VUR43_000285"
     CDS             11954..14161
                     /gene="nrdD"
                     /locus_tag="VUR43_000285"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET5412034.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            14173..14313
                     /locus_tag="VUR43_000286"
     CDS             14173..14313
                     /locus_tag="VUR43_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412035.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            14357..14863
                     /locus_tag="VUR43_000287"
     CDS             14357..14863
                     /locus_tag="VUR43_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412036.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            14856..15446
                     /gene="nrdG"
                     /locus_tag="VUR43_000288"
     CDS             14856..15446
                     /gene="nrdG"
                     /locus_tag="VUR43_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET5412037.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            15443..16060
                     /locus_tag="VUR43_000289"
     CDS             15443..16060
                     /locus_tag="VUR43_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET5412038.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            16327..16635
                     /gene="rpsJ"
                     /locus_tag="VUR43_000290"
     CDS             16327..16635
                     /gene="rpsJ"
                     /locus_tag="VUR43_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET5412039.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            16852..17478
                     /gene="rplC"
                     /locus_tag="VUR43_000291"
     CDS             16852..17478
                     /gene="rplC"
                     /locus_tag="VUR43_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET5412040.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            17503..18126
                     /gene="rplD"
                     /locus_tag="VUR43_000292"
     CDS             17503..18126
                     /gene="rplD"
                     /locus_tag="VUR43_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET5412041.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            18126..18422
                     /locus_tag="VUR43_000293"
     CDS             18126..18422
                     /locus_tag="VUR43_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET5412042.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            18440..19273
                     /gene="rplB"
                     /locus_tag="VUR43_000294"
     CDS             18440..19273
                     /gene="rplB"
                     /locus_tag="VUR43_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET5412043.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            19377..19658
                     /gene="rpsS"
                     /locus_tag="VUR43_000295"
     CDS             19377..19658
                     /gene="rpsS"
                     /locus_tag="VUR43_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET5412044.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            19670..20014
                     /gene="rplV"
                     /locus_tag="VUR43_000296"
     CDS             19670..20014
                     /gene="rplV"
                     /locus_tag="VUR43_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET5412045.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            20027..20680
                     /gene="rpsC"
                     /locus_tag="VUR43_000297"
     CDS             20027..20680
                     /gene="rpsC"
                     /locus_tag="VUR43_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET5412046.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            20684..21097
                     /gene="rplP"
                     /locus_tag="VUR43_000298"
     CDS             20684..21097
                     /gene="rplP"
                     /locus_tag="VUR43_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET5412047.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            21107..21313
                     /locus_tag="VUR43_000299"
     CDS             21107..21313
                     /locus_tag="VUR43_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET5412048.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            21338..21598
                     /gene="rpsQ"
                     /locus_tag="VUR43_000300"
     CDS             21338..21598
                     /gene="rpsQ"
                     /locus_tag="VUR43_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET5412049.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            21624..21992
                     /gene="rplN"
                     /locus_tag="VUR43_000301"
     CDS             21624..21992
                     /gene="rplN"
                     /locus_tag="VUR43_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET5412050.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            22070..22375
                     /gene="rplX"
                     /locus_tag="VUR43_000302"
     CDS             22070..22375
                     /gene="rplX"
                     /locus_tag="VUR43_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET5412051.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            22399..22941
                     /gene="rplE"
                     /locus_tag="VUR43_000303"
     CDS             22399..22941
                     /gene="rplE"
                     /locus_tag="VUR43_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET5412052.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            22959..23228
                     /gene="rpsN"
                     /locus_tag="VUR43_000304"
     CDS             22959..23228
                     /gene="rpsN"
                     /locus_tag="VUR43_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET5412053.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            23513..23911
                     /gene="rpsH"
                     /locus_tag="VUR43_000305"
     CDS             23513..23911
                     /gene="rpsH"
                     /locus_tag="VUR43_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET5412054.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            24103..24639
                     /gene="rplF"
                     /locus_tag="VUR43_000306"
     CDS             24103..24639
                     /gene="rplF"
                     /locus_tag="VUR43_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET5412055.1"
                     /translation="MSRIGNKVIVLSAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            24723..25079
                     /gene="rplR"
                     /locus_tag="VUR43_000307"
     CDS             24723..25079
                     /gene="rplR"
                     /locus_tag="VUR43_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET5412056.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            25097..25591
                     /gene="rpsE"
                     /locus_tag="VUR43_000308"
     CDS             25097..25591
                     /gene="rpsE"
                     /locus_tag="VUR43_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET5412057.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            25563..25787
                     /gene="rpmD"
                     /locus_tag="VUR43_000309"
     CDS             25563..25787
                     /gene="rpmD"
                     /locus_tag="VUR43_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET5412058.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            25932..26372
                     /gene="rplO"
                     /locus_tag="VUR43_000310"
     CDS             25932..26372
                     /gene="rplO"
                     /locus_tag="VUR43_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET5412059.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            26385..27695
                     /gene="secY"
                     /locus_tag="VUR43_000311"
     CDS             26385..27695
                     /gene="secY"
                     /locus_tag="VUR43_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET5412060.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDKTE"
     gene            27846..28484
                     /locus_tag="VUR43_000312"
     CDS             27846..28484
                     /locus_tag="VUR43_000312"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET5412061.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMVNQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKEGLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     KLGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            28601..28819
                     /gene="infA"
                     /locus_tag="VUR43_000313"
     CDS             28601..28819
                     /gene="infA"
                     /locus_tag="VUR43_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET5412062.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            28844..28960
                     /gene="rpmJ"
                     /locus_tag="VUR43_000314"
     CDS             28844..28960
                     /gene="rpmJ"
                     /locus_tag="VUR43_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET5412063.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            28978..29343
                     /gene="rpsM"
                     /locus_tag="VUR43_000315"
     CDS             28978..29343
                     /gene="rpsM"
                     /locus_tag="VUR43_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET5412064.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            29361..29744
                     /gene="rpsK"
                     /locus_tag="VUR43_000316"
     CDS             29361..29744
                     /gene="rpsK"
                     /locus_tag="VUR43_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET5412065.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            29787..30722
                     /locus_tag="VUR43_000317"
     CDS             29787..30722
                     /locus_tag="VUR43_000317"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET5412066.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            30734..31120
                     /gene="rplQ"
                     /locus_tag="VUR43_000318"
     CDS             30734..31120
                     /gene="rplQ"
                     /locus_tag="VUR43_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET5412067.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            31385..31651
                     /locus_tag="VUR43_000319"
     CDS             31385..31651
                     /locus_tag="VUR43_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET5412068.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            31661..32998
                     /locus_tag="VUR43_000320"
     CDS             31661..32998
                     /locus_tag="VUR43_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET5412069.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            33242..33934
                     /locus_tag="VUR43_000321"
     CDS             33242..33934
                     /locus_tag="VUR43_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET5412070.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(34037..35682)
                     /locus_tag="VUR43_000322"
                     /pseudo
     CDS             complement(34037..35682)
                     /locus_tag="VUR43_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(35732..36295)
                     /locus_tag="VUR43_000323"
     CDS             complement(35732..36295)
                     /locus_tag="VUR43_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412071.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRIPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEDLQKDNRIRLRINTQK"
     gene            complement(36319..36761)
                     /locus_tag="VUR43_000324"
                     /pseudo
     CDS             complement(36319..36761)
                     /locus_tag="VUR43_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(36774..37790)
                     /locus_tag="VUR43_000325"
                     /pseudo
     CDS             complement(36774..37790)
                     /locus_tag="VUR43_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(38007..38150)
                     /locus_tag="VUR43_000326"
     CDS             complement(38007..38150)
                     /locus_tag="VUR43_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET5412072.1"
                     /translation="MAESPNSPLSAISDQVGFSDYKYFAKVFKKHLHISPKELKLLGR
                     IVK"
     gene            complement(38249..38482)
                     /locus_tag="VUR43_000327"
     CDS             complement(38249..38482)
                     /locus_tag="VUR43_000327"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HET5412073.1"
                     /translation="MQYGAVDFLSKPIDTKELTECLQKIVLRLQISTSQETPFLEEYQ
                     TLLTSIQQVDTQNQIIQQIISFVHKHYAEHYYC"
     gene            complement(38531..38758)
                     /locus_tag="VUR43_000328"
     CDS             complement(38531..38758)
                     /locus_tag="VUR43_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HET5412074.1"
                     /translation="MFKLIIVEDEHLIRKWLEIAVDYSALGIQVVGTASHGQEGMKLI
                     QEKETHICLNRHHNANYGCFYDVQSHSYSFL"
     gene            complement(38762..39145)
                     /locus_tag="VUR43_000329"
     CDS             complement(38762..39145)
                     /locus_tag="VUR43_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5412075.1"
                     /translation="MIHKIRFEHFSYDIVCPETVDNQPIPKLFLLPLVENAIKHGMQY
                     RIDLHIDIHITLEADSLTFLVKDNAGGLTKQERFAILDSLESPHTQHGIMNSYKQLSN
                     FFSDVQLDLGVNRQGETWVKFVTKD"
     gene            complement(39478..40254)
                     /locus_tag="VUR43_000330"
     CDS             complement(39478..40254)
                     /locus_tag="VUR43_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET5412076.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            40376..41122
                     /locus_tag="VUR43_000331"
     CDS             40376..41122
                     /locus_tag="VUR43_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5412077.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            41135..42115
                     /locus_tag="VUR43_000332"
     CDS             41135..42115
                     /locus_tag="VUR43_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET5412078.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            42310..42630
                     /locus_tag="VUR43_000333"
     CDS             42310..42630
                     /locus_tag="VUR43_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5412079.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            42676..42984
                     /locus_tag="VUR43_000334"
     CDS             42676..42984
                     /locus_tag="VUR43_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5412080.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            43001..44299
                     /locus_tag="VUR43_000335"
     CDS             43001..44299
                     /locus_tag="VUR43_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5412081.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGTIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            44450..46888
                     /locus_tag="VUR43_000336"
     CDS             44450..46888
                     /locus_tag="VUR43_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET5412082.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            46907..47575
                     /locus_tag="VUR43_000337"
     CDS             46907..47575
                     /locus_tag="VUR43_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET5412083.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            47593..48681
                     /locus_tag="VUR43_000338"
     CDS             47593..48681
                     /locus_tag="VUR43_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET5412084.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            49136..51637
                     /locus_tag="VUR43_000339"
     CDS             49136..51637
                     /locus_tag="VUR43_000339"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET5412085.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGDVKEAAYTEDGLHVNSDFLDELNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            51937..52173
                     /locus_tag="VUR43_000340"
     CDS             51937..52173
                     /locus_tag="VUR43_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET5412086.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELTSIDLLEGRYARIEALSVEKHA
                     EDLLAVYGPDTLQEMWTYFFQEPVADMEELVSLL"
     gene            52273..52735
                     /locus_tag="VUR43_000341"
                     /pseudo
     CDS             52273..52735
                     /locus_tag="VUR43_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398415.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            52747..53133
                     /locus_tag="VUR43_000342"
     CDS             52747..53133
                     /locus_tag="VUR43_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412087.1"
                     /translation="MITIRKQEIVKFEDVLHLYQAVGWTNYTNQPQMLEQALYHSLVI
                     YLALDGDAVVGLIRLAGDGFSSVFVQDLIVLSSYQRQGIGSSLMKQALGNFKEAYQVQ
                     LATEQTEKTWDLIVLWALKSYPPIIG"
     gene            complement(53789..53881)
                     /locus_tag="VUR43_000343"
     CDS             complement(53789..53881)
                     /locus_tag="VUR43_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET5412088.1"
                     /translation="MIELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            54042..55013
                     /gene="ruvB"
                     /locus_tag="VUR43_000344"
     CDS             54042..55013
                     /gene="ruvB"
                     /locus_tag="VUR43_000344"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET5412089.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            55102..55566
                     /locus_tag="VUR43_000345"
     CDS             55102..55566
                     /locus_tag="VUR43_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET5412090.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            55797..56555
                     /locus_tag="VUR43_000346"
     CDS             55797..56555
                     /locus_tag="VUR43_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET5412091.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            56564..57367
                     /locus_tag="VUR43_000347"
     CDS             56564..57367
                     /locus_tag="VUR43_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET5412092.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            57389..58648
                     /gene="rseP"
                     /locus_tag="VUR43_000348"
     CDS             57389..58648
                     /gene="rseP"
                     /locus_tag="VUR43_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET5412093.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTASTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            58661..60514
                     /locus_tag="VUR43_000349"
     CDS             58661..60514
                     /locus_tag="VUR43_000349"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET5412094.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            60614..61993
                     /gene="bglA"
                     /locus_tag="VUR43_000350"
     CDS             60614..61993
                     /gene="bglA"
                     /locus_tag="VUR43_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET5412095.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            62186..63994
                     /gene="glmS"
                     /locus_tag="VUR43_000351"
     CDS             62186..63994
                     /gene="glmS"
                     /locus_tag="VUR43_000351"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET5412096.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEVKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            64113..65162
                     /locus_tag="VUR43_000352"
     CDS             64113..65162
                     /locus_tag="VUR43_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET5412097.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(65262..69059)
                     /gene="spuA"
                     /locus_tag="VUR43_000353"
     CDS             complement(65262..69059)
                     /gene="spuA"
                     /locus_tag="VUR43_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET5412098.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDINTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYRTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGPVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRNESVENSSKENIPATPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            69476..69889
                     /gene="rpsL"
                     /locus_tag="VUR43_000354"
     CDS             69476..69889
                     /gene="rpsL"
                     /locus_tag="VUR43_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET5412099.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            69909..70379
                     /gene="rpsG"
                     /locus_tag="VUR43_000355"
     CDS             69909..70379
                     /gene="rpsG"
                     /locus_tag="VUR43_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET5412100.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            70804..72885
                     /gene="fusA"
                     /locus_tag="VUR43_000356"
     CDS             70804..72885
                     /gene="fusA"
                     /locus_tag="VUR43_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET5412101.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            72989..77380
                     /locus_tag="VUR43_000357"
     CDS             72989..77380
                     /locus_tag="VUR43_000357"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET5412102.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKNLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     EEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            77482..77745
                     /locus_tag="VUR43_000358"
     CDS             77482..77745
                     /locus_tag="VUR43_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET5412103.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            77738..78016
                     /locus_tag="VUR43_000359"
     CDS             77738..78016
                     /locus_tag="VUR43_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET5412104.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARN
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            78037..78189
                     /locus_tag="VUR43_000360"
     CDS             78037..78189
                     /locus_tag="VUR43_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412105.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            78211..79452
                     /locus_tag="VUR43_000361"
     CDS             78211..79452
                     /locus_tag="VUR43_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET5412106.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            79462..79692
                     /locus_tag="VUR43_000362"
     CDS             79462..79692
                     /locus_tag="VUR43_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET5412107.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            79713..79787
                     /locus_tag="VUR43_000363"
                     /pseudo
     CDS             79713..79787
                     /locus_tag="VUR43_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            79960..80682
                     /locus_tag="VUR43_000364"
     CDS             79960..80682
                     /locus_tag="VUR43_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET5412108.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            80900..82234
                     /gene="pepC"
                     /locus_tag="VUR43_000365"
     CDS             80900..82234
                     /gene="pepC"
                     /locus_tag="VUR43_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET5412109.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(82290..83201)
                     /locus_tag="VUR43_000366"
     CDS             complement(82290..83201)
                     /locus_tag="VUR43_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5412110.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(83225..84028)
                     /locus_tag="VUR43_000367"
     CDS             complement(83225..84028)
                     /locus_tag="VUR43_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET5412111.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(84056..85045)
                     /gene="manX"
                     /locus_tag="VUR43_000368"
     CDS             complement(84056..85045)
                     /gene="manX"
                     /locus_tag="VUR43_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET5412112.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(85278..86297)
                     /gene="adhP"
                     /locus_tag="VUR43_000369"
     CDS             complement(85278..86297)
                     /gene="adhP"
                     /locus_tag="VUR43_000369"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET5412113.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(86636..87448)
                     /locus_tag="VUR43_000370"
     CDS             complement(86636..87448)
                     /locus_tag="VUR43_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5412114.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            87638..89056
                     /locus_tag="VUR43_000371"
     CDS             87638..89056
                     /locus_tag="VUR43_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET5412115.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGI
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIYWDDMSEAVPVFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            89109..89816
                     /locus_tag="VUR43_000372"
     CDS             89109..89816
                     /locus_tag="VUR43_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5412116.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            89911..90885
                     /gene="folP"
                     /locus_tag="VUR43_000373"
     CDS             89911..90885
                     /gene="folP"
                     /locus_tag="VUR43_000373"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET5412117.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLI
                     FPHFGFGQAFTEEELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEEIGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            90887..92209
                     /locus_tag="VUR43_000374"
     CDS             90887..92209
                     /locus_tag="VUR43_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET5412118.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLFDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTIRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            92190..92744
                     /gene="folE"
                     /locus_tag="VUR43_000375"
     CDS             92190..92744
                     /gene="folE"
                     /locus_tag="VUR43_000375"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET5412119.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            92787..93599
                     /gene="folK"
                     /locus_tag="VUR43_000376"
     CDS             92787..93599
                     /gene="folK"
                     /locus_tag="VUR43_000376"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET5412120.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLET
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(93644..93961)
                     /locus_tag="VUR43_000377"
     CDS             complement(93644..93961)
                     /locus_tag="VUR43_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET5412121.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            94317..94763
                     /gene="rplM"
                     /locus_tag="VUR43_000378"
     CDS             94317..94763
                     /gene="rplM"
                     /locus_tag="VUR43_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET5412122.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            94782..95174
                     /gene="rpsI"
                     /locus_tag="VUR43_000379"
     CDS             94782..95174
                     /gene="rpsI"
                     /locus_tag="VUR43_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET5412123.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(95436..96617)
                     /locus_tag="VUR43_000380"
                     /pseudo
     CDS             complement(95436..96617)
                     /locus_tag="VUR43_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678337.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(96577..97245)
                     /locus_tag="VUR43_000381"
                     /pseudo
     CDS             complement(96577..97245)
                     /locus_tag="VUR43_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            complement(97332..97802)
                     /locus_tag="VUR43_000382"
     CDS             complement(97332..97802)
                     /locus_tag="VUR43_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412124.1"
                     /translation="MTRVYKSVRLAYEAKVWIDELIQEKERKIQELNKEDFLDKLEKT
                     LLKNHYDELNGLSFNIILKASIGSVIEESYRNTKHYQIDKWQKLRQQMERDVKNVNPN
                     LETTVTPRIYLDEDVLAGLDDFRYVLMKEDCATRLPRLSYIIKLVVYSYWKEQH"
     gene            complement(97799..98689)
                     /locus_tag="VUR43_000383"
     CDS             complement(97799..98689)
                     /locus_tag="VUR43_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412125.1"
                     /translation="MDNTKVIEWLNYCDQNDIKPWLWDFKNCYSSELTADNISNFLKY
                     KNGELVNPSTFCITKQVGSNADCDKEALPLYNVLGWQHSERDIIRGETLNSYITTFTQ
                     AITNDPNYKEICKKIGVNLNEYLNKQYPILHHNKNYQNFKMIQKNLKEFEAFAKLTHT
                     IGNFTVLPHWMNTGRYNFSKDYWDITMLSLQEWLTNLSPQAWKNFIDTYYLQPYVDNN
                     YQTEVFWETHNYEYIYPKKTEDFSIFLKRVNERIEERGKFIIKQICDKLNKKDFHFYK
                     EIENMDKIKYSNEFEQERKQ"
     gene            98892..100103
                     /locus_tag="VUR43_000384"
     CDS             98892..100103
                     /locus_tag="VUR43_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412126.1"
                     /translation="MKKVIEMFPEFHQEKLETTDIKDENNLIVVDTNFLLQILELPID
                     IATKYVDSLKSIKRNLYIPYLVALEFHFNKSNKKKTKKRNADSYFKQVESALNQLKSS
                     VQNTDLIKMDIENGKLKHLIGNLEFFTDDFLAKVNLFVRDEITDKEDEVYKELLNIIS
                     DSIGDVYEQEWIYEIEKEGEKRFAEAIPPGFNDENKDGIRKYNGISYHQKYGDLIIWK
                     DILKKATEQPRGDKVIFITNDGESNKKSDLIYKTSNMKVGPSIFLMNELYMCSRKKLY
                     ILNNTTLVNMITELSEDEIDRIEAQEEKKYVVTFPKWILDKAEKDVRARNESNNSSVV
                     YYIDSENRLASIDIDEVEPLELISLLENPDVKKMLKEEILKKMLDGYYSKLPRHIIKD
                     IINSYQEKNIQ"
     gene            complement(100658..101059)
                     /locus_tag="VUR43_000385"
     CDS             complement(100658..101059)
                     /locus_tag="VUR43_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5412127.1"
                     /translation="MLFFSISNDLLQLLTSWKEQQRYELAKFGILSNPEQFVFTYIDT
                     KGNINKPLHADYLNNKMKSIRKRHKELTHATPHKLRHTGATLAKKAGMSLEAISKALT
                     HSDTGTTQIYVNTSNVVPMTVGEFALKSLKQ"
     gene            complement(101435..102643)
                     /locus_tag="VUR43_000386"
     CDS             complement(101435..102643)
                     /locus_tag="VUR43_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5412128.1"
                     /translation="MNYIKRPHYLDFLRRHRDRQIIKVVSGVRRAGKSVLFQLYKEEL
                     IATGVDEDQIISINFEDLSYYDLRHFQTLFAYIKEQLIGEKTYYIFLDEIQHVEKFEL
                     VADSLFILPNVDLYLTGSNAYFMSSQLATNLTGRYVEIEVLPLSFEEYLSGQSLTENL
                     NTTEIFNNYLFSAFPYLLQTSSYAEKIDYLRGIYNSILLNDIVTRLGNPNPTIIERIV
                     RTLLSSTGSLISTNKIRNTLVSQNVSISHNTLENYLTTLTDSLLFYSVPRFDVKGRAL
                     LQRLEKYYPVDLGLRHLLLPDHKEDIGHILENMVYLELRRRYSQVYVGNLDKYEVDFV
                     VVTDLGHYAYYQVSETTLAPETLERELRPLDAIKDQFPKYLLTMDTIQPTANYNGIEK
                     KNIIDWLLEK"
     gene            103048..103224
                     /locus_tag="VUR43_000387"
     CDS             103048..103224
                     /locus_tag="VUR43_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412129.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            103625..105838
                     /locus_tag="VUR43_000388"
     CDS             103625..105838
                     /locus_tag="VUR43_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET5412130.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
BASE COUNT        32042 a        19093 c        23352 g        31524 t
ORIGIN      
        1 ttttgggtaa tagaatctca ctttttttgg tataatggta agcaataatg gactagaaag
       61 aacaaagatg caagataaaa ttgtcattca tggggcgcgt gcccataatt taaaaaatat
      121 tgatgtggag attccgcgag acaagttggt tgtcgtgact ggcttgtcag gttcagggaa
      181 gtccagtctg gcttttgata ctctctatgc ggagggacaa cgtcgctatg tagagagttt
      241 gtctgcctac gctcgtcagt tcttgggaaa tatggaaaaa ccagatgtag atgccattga
      301 tggtctcagc ccagctattt ccatcgacca gaaaacgact agtaaaaatc ctcgctcgac
      361 ggtgggaacg acgactgaaa tcaatgacta tctgcgtctc ctctacgcac gtgtggggac
      421 gccttactgt atcaacggac atggagctat caatgcttct tctgtggagc aaatcgttga
      481 taaggttttg gagttacctg aacgccagcg cttgcagatc ttggctcctg tcatccgcaa
      541 gaaaaaaggc caacataaga gtgttatcga gaaggttcag aaagacgggt atgttcgtgt
      601 tcgtgtggat ggggaagtct atgatgtgac cgaagtgcca gagttgtcta agagcaagca
      661 acacaatatc gatgtcgtgg ttgaccgtat tgttatcaag gagggcattc gtagccgtct
      721 ctttgattcc attgaagctg cccttcgtat cgcagaaggt tatgtgatta tcgacaccat
      781 ggacgactct gagttgttgt tctctgagca ttatgcctgt ccagtttgtg gatttactgt
      841 cccagagtta gaacctcgtc tcttctcttt caatgctccc tttggctctt gtagtgagtg
      901 tgacggcttg gggattaagc tggaggtgga tactgatttg gtagtgccag atgccagcaa
      961 aaccttacat gagggagcgc tggcaccttg gaatcctatc tcatccaact actatccaaa
     1021 catgttagag caggccatga aagtctttgg agtggctatg gataagcctt ttgaggacct
     1081 gtcagaagaa gataagaact tgattctcta tgggtcagat ggtaaggaat tccatttcca
     1141 ctatgagaat gaatttggtg gcgtgcgcga tatcgacatt ccgtttgagg gagttatcaa
     1201 taatatcaaa cgtcgttacc atgaaaccaa tagcgattac actcgcactc agatgcgtct
     1261 ctacatgaat gagctgacct gcggaacctg tcaaggctat cgtctcaatg accaggcctt
     1321 gtctgtccgt gtgggcggcc agcaagggcc acatattgga gaaatctcag acctgtctat
     1381 cgctgaccac ttggacttgg tgagccagtt aactttgtct gaaaatgaag ccatcattgc
     1441 tcgtcccatt ctcaaggaaa tcaaggatcg tttgaccttc cttaataatg tgggtcttaa
     1501 ctatctaacc ctgtcacgtt cagcaggaac cctttcaggt ggggaaagtc agcgcattcg
     1561 tttggcaacc cagattggtt ccaacctatc aggcgtcctc tatatcctag acgagccgtc
     1621 aatcggtctt caccagaggg acaatgaccg cctgattgcc agtctgaaaa agatgcgtga
     1681 cttgggcaat actcttatcg tggtggaaca cgacgaagat accatgcgtg aagctgatta
     1741 tctgattgac gttggtcctg gtgccggtgt ttttggtggt gagattgttg cagcaggtac
     1801 acctaagcaa gtggctcgca acagcaagtc tatcacaggt cagtacttgt caggcaaacg
     1861 tgtcatccca gtaccagaag agcgccgtgt cggaaatggt cgttttattg aagtgatagg
     1921 agcgcgtgag aacaacttgc aaaatgtcac ggctcgcttt ccactaggaa aatttatcgc
     1981 agtgacaggt gtgtcgggtt cagggaaatc gactctaatc aacagcattc tcaaaaaagc
     2041 cattgcccag aagctcaacc gtaattcaga caaacctggt aagtttaaga ctattacagg
     2101 gattgagcat gtcgaccgtt tgattgatat tgaccagagc cctatcggac ggacgccgag
     2161 atctaaccca gctacctata caggagtttt tgacgatata cgtgaccttt ttgctcagac
     2221 aaatgaagcc aagattcgag gctacaagaa ggggcgcttc agtttcaacg tcaagggagg
     2281 tcgctgtgaa gcttgctcag gtgacgggat tatcaagatt gagatgcact tcttgccaga
     2341 tgtttatgtg gcttgtgaag tttgccacgg aacccgctat aacagtgaaa ccctagaagt
     2401 tcactacaag gaaaagaata tttcgcaggt cttggatatg acggtcaacg atgcggtaga
     2461 atttttccaa cacattccga aaattcaacg caaactccag accatcaagg atgtaggtct
     2521 aggctatgtg accttgggac agccagctac caccctttct gggggagaag cccaacgtat
     2581 gaagttagct agcgaactcc acaaacgctc gacaggaaaa tctttctaca ttctggatga
     2641 gccgacgaca gggcttcata cagaggacat tgctcgcctg ctcaaggttt tagctcgctt
     2701 tgtagacgac ggcaatacag tcctcgtcat cgagcacaat ctggatgtta tcaagacggc
     2761 agaccatatc attgacttgg gacctgaggg cggtgtcggt ggtggaacca tcatcgtaac
     2821 aggaactcca gaagaagtag ctgccaacga agccagctat acaggacact atttgaaagg
     2881 aaagttacat catgaataaa cgcgtacaag catttctagc taaaatgcaa gaaaaagaac
     2941 tagatggtat catcatcaac aatcttaaaa acgtctatta tttgactggt ttttggggct
     3001 caaacggaac agtctttatc agccgtgacc gtcaggtctt agtgacagac tctcgctata
     3061 tcatcgcagc taagcaagaa accagtggtt ttgagattgt ggctgatcgt gatgaattgg
     3121 ctgtcattgc aggaattgtt aaggacatgg gcttgactcg tatcggtttt gaagatgaga
     3181 tttcagtgtc ttattaccac cgtatgcagg cagcttttgc aggtttgaac ttgcttccac
     3241 aaactcagtt tgtggaaggt cttcgtatga ttaaggatga ggcagagatt gcagcgattc
     3301 gcaaggcttg ttctatctca gaccaagctt tccgcgatgc gcttgacttt atcaaaccag
     3361 gaaaaactga aattgagatt gccaacttcc ttgatttccg catgcgtgag ttgggagcat
     3421 ctggcttatc ttttgatacg atcctagcta gcggtatcaa ttcttctaaa ccccatgccc
     3481 atccaatgca caaaccagtg gagttgggag aagccattac catggacttc ggctgtctct
     3541 atgaccacta tgtcagtgat atgacccgga ctatctatct agggcatgtt agcgatgagc
     3601 aggcagagat ttacaatacg gttctaaaag ctaaccaagc cttgattgac caagctaagg
     3661 caggcttagg tttccgtgac tttgacaaaa tccctcgtga tattatcatt gaggcaggtt
     3721 atggtgacta ctttactcac ggcattggcc acggtattgg tctggatatc catgaggaac
     3781 cctactttag tcagacttct acagaaacta ttaagacagg tatggccttg accgatgaac
     3841 caggtatcta tatcgaaggc aaatatggcg ttcgtatcga ggatgatatc ctgattacag
     3901 agacaggttg tgaattattg accctagctc caaaagagtt gatagtcatt tagttgtttg
     3961 tcaagaaaaa agtacgaaaa tgacgaaaaa agtcaaaaaa aattaaaaat aggtcgcaag
     4021 tcggatgttt tttatggtat aatagactaa actgatagta acatgtagcg aaaggggtag
     4081 gtacatgatt aaaatttata cagtctcaag ttgtactagc tgtaaaaaag caaaaacctg
     4141 gctcaatgcc caccagttaa gttataaaga acaaaacctt ggtaaagaag gaattacgag
     4201 agaagaatta ctggatattc taaccaaaac agataacgga atagccagca tcgtttcgtc
     4261 taaaaatcgc tatgccaaag cccttggagt ggatattgaa gatttgagtg tcaatgaagt
     4321 tctcaatctg attatggaaa caccgagaat tttaaagagc ccaatccttg tagatgaaaa
     4381 acgcctgcaa gttggctaca aggaagacga tattcgtgcc ttcctaccac gctctgtccg
     4441 taatgtagaa aatgcagaag cacgtttgcg tgcagctcta taaacatcaa ggctgggagc
     4501 acttcccagt cttattctat tttaatttca aaaagaaaga agaaagaaat gaaaaaaata
     4561 gttcttgtta gtctagcttt cctttttgtc ctggttggtt gcggacagaa aaaagaaact
     4621 ggaccagcta caaaaacaga aaaagatacg cttcagtcgg cattgccagt tattgaaaat
     4681 gctgagaaga atacagttat aactaagact ttggtcttgc ccaagtcaga tgatggtagc
     4741 cagcagacac aaacaattac ttacaaagac aagacttttt tgagtctagc tatccaacaa
     4801 aaacgtccag tctctgatga gttgaagact tatattgacc aacatggagt ggaggaaact
     4861 caaaaagctc ttcttgaagc ggaggagaag gataagtcta tcattgaagc tcgtaaattg
     4921 gcaggtttca aacttgaaac aaaactattg agcgcaacgg aacttcaaac aacgactagt
     4981 tttgattttc aagttctgga tgtcaagaag gcttcccagt tggaacatct gaagaatatt
     5041 ggtttggaaa atcttttgaa aaatgaacca agcaaatata tttcagatag attggcaaat
     5101 ggcgcgacag aacaatagaa aatccaaata aatagactgc ctgaattgta gaaggtaagg
     5161 aattatgcta taatggtact attctaagga aagagggtgt tagaatggga tttactgaag
     5221 aaacagtacg ttttaaattg gacgattcca ataaaaaaga aattagcgaa actttgacag
     5281 atgtttatgc ttcgttgaac gataagggtt acaacccaat taaccaaatc gtaggttacg
     5341 tattgagtgg agaccctgcc tacgttcctc gttataataa tgcacgaaat caaatccgta
     5401 agtatgagcg tgatgaaatc gttgaggaat tggttcgcta ctacctcaaa ggacaaggag
     5461 tcgatctata acctatgaga attatgggat tggacgtcgg ttcaaaaacg gtaggggtgg
     5521 cgattagcga tccgcttggt tttacagctc aagggcttga aatcatccag ataaatgaag
     5581 aacaaggcca atttggtttt gaccgcgtta aggaattggt tgatacttac aaggtggaac
     5641 gatttgtagt gggcttgcct aaaaacatga acaatacaag tggaccgcgc gtagaagcta
     5701 gtcaagccta cggagcaaag ctagaagagt tttttggttt accagtagac tatcaggatg
     5761 aacgcttgac aacagtggct gctgagcgca tgttgattga acaagcagat atcagtcgca
     5821 ataagcgcaa gaaagtcatt gataagttag cagctcagct gattttacaa aattatttag
     5881 atagaaaatt ttaatataaa ggagaggcta tgtcacacga tcataaccac gaccacgaag
     5941 aacgtgaact aatcacacta gtagatgagc aaggaaatga aaccttgttt gaaatccttt
     6001 tgacaattga tggaaaagaa gaatttggta aaaactatgt tcttctagta ccagttaatg
     6061 cagaagaaga cgaagacgga caagttgaaa tccaagctta ctcattcatc gaaaacgaag
     6121 atggaacaga aggcgaattg caaccaatcc cagaagactc agaagacgaa tggaacatga
     6181 ttgaagaagt cttcaacagc tttatggagg agtaaaaacg tccgggggac gtttttagcc
     6241 ctgcgctaga aattagaaac gcaggtagtc tgggagactg tatcagccca actcccagaa
     6301 atggggaaga gttggaacat ccagtggatg tttttagccc agttccttta aataagagag
     6361 aactggtagg ttcgggggac gtttttagcc tgacgctaaa aataaaaacc gtcagtaagt
     6421 ccggggggcg tttttagccc acgttcacat tcatagtagc tagttattag ctaaccaggt
     6481 aagaggtcgg gacgaaaatc ctggccttgt ttttattagt aaccatactt taatgcgata
     6541 attgattgga cttttgtcaa ggagatgtgt atgtttgaag tagaagaatg gcttcatagt
     6601 cggattggtt tgaattttcg atcaggtttg ggccgaatac agcaagcggt ggatttgtta
     6661 ggaaatcctg agcagtctta ccctattatc cacgtaacag ggactaatgg gaaaggatct
     6721 accattgctt ttatgaggga attatttatg gggcatggca aaaaagttgc gacctttacc
     6781 tcccctcata tcgtatccat caatgaccga atttgcatta atgggcaacc tatagcagac
     6841 gcagacttta tccgtttggc tgatcaggta aaggagatgg agaaaacgct tctgcaaact
     6901 cctgaccagt tgtccttttt tgaattgctg accttggttg cttttcttta ttttagggag
     6961 caggaggtgg atttggtttt attagaagtg ggaattggtg gcttacttga cacgaccaat
     7021 gtggtaactg gagagcttgc tgtcatcacc tccattgggc ttgaccatca agaaaccttg
     7081 ggtgatagtc tagaagcaat tgcagagcag aaagctggta ttttcaaggc tggtaaaaag
     7141 gcagtgattg cgaaattgcc tccagaagct agacttgtct gtcagaaaaa agccgaatct
     7201 ttagctgttg acctttatca ggcaggtcaa gatttttcag tgctgaatgg tgatttttca
     7261 agctctttac taaatctttc acagctgaac ataggcttag aaggagccta tcagcaggag
     7321 aatgcggcct tggcgttgca aacttttctt ctttttatgg gagaaagaaa ggaagctatt
     7381 gatgaacagg ctgtaagaaa ggccttggaa cagacccatt gggctggtcg cttggagcgt
     7441 attcgcccac agatttactt ggatggtgct cataacctcc ctgccttgac tcgcttggtt
     7501 gagtttatca aagaaaaaga gcaggaaggc tatcgacctc aaatcctctt tggatccttg
     7561 aaacgtaagg attatcaagg gatgttgggt tatctgactg aaaatttacc tcaagtggaa
     7621 ctcaaaatga ccggctttga ctatcaaggg tctttggacg agacagatgt aacaggttac
     7681 catgtaattc cctcttaccg agaatttatc agcagtttcg aagaaagggc agacgctcaa
     7741 gacttgctgt tcgttacagg gtctctctat tttatctcag aagtacgggg ctacctgctg
     7801 gaccgtgagc agataaattg accccctttt ttgaacttgt tatactaggg gaattgctgg
     7861 ttagagaaaa tttctctaaa ttggtagcag aaaggaaatt catcatgaaa ttaaaaagat
     7921 tcacactttc tcttgcttct ctagcaagtt ttagtctctt agtagcttgt tcacaaagag
     7981 ctcaacaggt tcaacagcct gttgctcagc aggtccaaca gcctgctcaa cagaatacca
     8041 atactgcaaa tgcaggaggt aaccaaaatc aagcggctcc agtacaaaac caacctgttg
     8101 ctcaaccgac cgatattgat gggacttata ctggtcagga tgacggagac cgtatcactt
     8161 tagtggtaac tggaacgact ggtacatgga ctgagctcga atctgacggg gatcagaaag
     8221 tcaaacaggt tacatttgat tcagcaaatc aacgcatgat tattggcgat gatgtcaaaa
     8281 tttacactgt aaacggtaat caaatcgtcg tagatgatat ggatagagac ccatcggacc
     8341 aaatcgtttt aactaaataa gactatgcaa gtagaaaggg ctggattttt cagccttttt
     8401 acttttacct agaaaataat cataaatact tgccttctac cgaatacctg cgttatacta
     8461 gtatcaatta cttgttttta gcattcaaac tatcaaggag gggatatgaa atataggaaa
     8521 tttcaattat tgatgtccaa gtatggcttt agtctttcga ttatgctact tgaactttgt
     8581 cttgtttttg gtctctttct ttatttagga cgcatggctc ccattttatg gattactgtc
     8641 ctcattctac tgagtatcat cacaatcatt tcgatagtca accgtaatac gactcctgag
     8701 aataaggtaa cctggttgtt agtagccttt gtgccagtat ttggtccctt gctctatctg
     8761 atgtttggtg aaaggcgatt gtccaaaaaa gaaattaaac aactgaagaa gctaggctct
     8821 atgcatttcc aagaagcaaa tagccagcta ctaaaagaga aattaaaaga aagtgacaag
     8881 gcagcttatg gagtcatcaa gtccttattg agtatggata ccaatgctga catctatgat
     8941 caaactgcct ctacattttt tcctaacgga gaagctatgt ggaaaaagat ggtagaagat
     9001 cttaaaaagg ctgagaaatt tattttcttg gaatattaca ttatagaaga aggtttgatg
     9061 tggaatcgca tactagatat actagagcaa aaggtagctc agggtgtaga ggttaagatg
     9121 ctctatgatg atatcggctg tatggctact ttaacaggag attatgcaca tcgacttcgt
     9181 cagctgggca tcgaggccca taaattcaat aaagttattc ctcgtttgac agtggcttat
     9241 aataacagag atcatagaaa aatattgatt gttgatggtc agatagccta tactggtggg
     9301 gtcaatctgg cagatgagta cattaaccac gtcgagagat ttggttattg gaaggatagt
     9361 ggaattcgct tagacggact agcagtaaaa gctctgacac gcttattttt gaccacttgg
     9421 tacattaatc gaggagaaat tagtgatttt gatcaatatc atttagaaaa tcattctatc
     9481 ccgagtgacg gtttaaccat tccatacgga agtggaccca agccaatttt tcgagcgcag
     9541 gtagggaaaa aagtttatca gagtttaatc aatcaagcaa cagaatcggt ctatattacg
     9601 acaccttatt tgattataga ttatgattta acagagacaa tcaaaaatgc agctatgaga
     9661 ggggtcgatg ttcgaattat caccccttac ataccagata agaagttcat tcagttagtc
     9721 acgagaggag cttatcccga ccttctttct gctggtgttc ggatttatga gtatagtcca
     9781 ggttttattc atagtaagca gatgttggta gacgaagatt ttgcggtggt ggggacaatc
     9841 aatctcgact accggagctt ggtacaccat tatgaaaatg cagtcttact ctataaaact
     9901 ccttctataa gggaaatcgc ccgagatttt cgaaatatat ttgcagattc tcaggaagtc
     9961 tatcctcatt ctatcaaaac gagctggtat caaaagcttg taaaagaaat cgcccagcta
    10021 ttcgccccta tcttataaga aatctagaac ttaggataca aaccagacct atttttcttg
    10081 tcttttacga atagaaagaa agaggagggg aattcatgct aactaaggaa gaagtgaatg
    10141 atatgattga gttcaaacag acacatttac accgctttcg ggaaattgaa acctttgtga
    10201 aactatgcaa aaaatcactc aaacagccat cgcaagctga caatcctagg actttttgat
    10261 atactaagac agataaattg aacaggagaa acgatatgag tgtgtatggt agagtagaag
    10321 aagttcataa ggagaatcgt gaacctctag aataccaaat cgaacaagaa tcgcatcatc
    10381 gtgaatcaag tcgtcttcct ttggtgaaaa ttttactatg gagtacgctt gtaacgggga
    10441 taactctagg agtaccgcta ttactcgact taatgagtgc acaagaagtg caggattttt
    10501 atgcaggttg ggcgcttcat cagacaggga agatttacag cgactattat ggaagtcaag
    10561 gtttgcttta ttatttgctg acttacgtga gtcagggcgg atttttcttt gccatctttg
    10621 agtggttagc cttggtagca ggaggatttt tcctttttag atcagcggac accttgacag
    10681 agcaaggaga ccaagctgga catctggtga ctatttttta catgctagtt acaggtcttg
    10741 cttttggtgg aggctatgcg actcttttag cgcttccttt cttattcgca gcctttagtt
    10801 tagttgcggc ttacctaagc aatccaagcc atgataaggg atttgtacgg attgggctag
    10861 ctttggcagg cggatttttc tttgctccct tatcatcgct cctgtttatt gctgtagtga
    10921 gtttaggctt gttggtcttt aaccttgggc atagacgctt tgcgcatggg ttttatcagt
    10981 ttcttgcagt ggctttaggt ttttcacttg tcttttatcc aactgcctac tatagtgctg
    11041 caacaggaag ttttggggat gcgattagtg gtattcgtta tcctattgac agtattcgct
    11101 ttgattttac ttctaaaatt ttagagaata tgttttttta tggcttgttg tcccttggtt
    11161 tgggatttgt ggtttgtatc tttttaggtc tctttcaatc caaacccttt aaactatacg
    11221 tcatttcggt tcctgcaagt cttgtggtaa ttttaggttt gattttactt ttcttttcac
    11281 aagagcctct gcacgcttct tatttgatgg tcgtcttccc tgttttccta cttttattgg
    11341 taaccaatat taagagtcaa cagagggggc gtggtgttag aagaagccga agagaaacgc
    11401 cagttagcct atggagtcgt ttcttcaaag gaaatctata tctgctagtt tttgggcttg
    11461 tctatctttt gtctgttcct tttttgatga agtttgtcct ttatccggta ccttatcaag
    11521 aacgtaatcg tcttgctgat ttggtaaaag aggagacaaa tacggaagat actatctatg
    11581 catgggatga tactgcgact ctttatcgta agagtgagcg cttgtcgcca tcggcgattt
    11641 tgtccccgtt gcactataca gcaactgagg aaaatcgtaa taagttactt aatgacttga
    11701 aagaaaaaca acctaaggtg attgtggtaa atgacaaggt ggtagtctgg tctgaagtgg
    11761 aaacactctt aaaagaaaat taccaacaag taaagactga ttactcagag tttaaagtct
    11821 ataaaattaa ataaccaaat caatatcttg tgtattttta aaaattttag gatttttaac
    11881 acaagatatt gatttttctt tttagagtgg tataatactt tttagaaaga acattttaga
    11941 aaagagcatg catatgattg cactagaaga aaaaattaca attttgccaa ctctcttcgt
    12001 cgagaaacga gatgggagac gtgttgtatt tgatgtggac aagattgaca aggctctcca
    12061 caaggcggct gacaaggtta tggatgtgac acccctggtt gaaaaacgcc tcaatgatct
    12121 gactgagcga attattacag aaattcatag tcgctttcca cagggaatta agatttacga
    12181 aattcaaaat atcgtagaac atgaactcct tgaagccaaa gaatatgcgc tggctgagga
    12241 gtatattact tatcggacac agagggattt tgagcgctca aaagcgacgg atatcaactt
    12301 tagtattcat aaacttctca acaaagacca gacagttgtc aatgaaaatg ctaataaaga
    12361 cagtgatgtc tttaacactc agcgtgattt gacagcaggg attgttggga aatcaatcgg
    12421 actgcaaatg cttcctaagc acgtagccaa tgcccaccaa aagggggata tccactatca
    12481 cgatttggac tacagtccct atacccctat gaccaactgc tgtttgattg attttaaggg
    12541 tatgttggaa aatggtttta agattggaaa tgcagaggta gagagtccca agtctatcca
    12601 gactgcgaca gcacagattt ctcaaatcat tgccaacgtt gcttctagcc agtacggtgg
    12661 ctgttcagct gaccgtatcg atgaaatttt ggcgccttat gcagagaaga actatcaaaa
    12721 acatctcaaa gatgcagaag agtgggtatt gcctgaaaaa cgggaagatt acgcttggaa
    12781 gaaaacgcaa aaggacatct acgatgccat gcaatctctt gagtatgaaa tcaatactct
    12841 cttcacttca aatggacaaa caccttttac ttcgttaggt tttggtctgg gaaccagtcg
    12901 ttttgaacga gaaattcaaa aagctatttt aaacattcgc atcaagggtc ttggttcaga
    12961 acaccgtacg gctatctttc ctaaacttat ctttacgctt aaaagaggcc tcaacttaga
    13021 ggaaggaact cccaactatg acatcaagca gttggctcta gagtgtgcaa ccaagcggat
    13081 gtatccagac gtcttgtctt atgataagat tgttgatttg acaggttctt tcaaagttcc
    13141 tatgggctgc cgttctttcc ttcaagggtg gaaggatgaa aatggtgtag aagtcaattc
    13201 aggtcgcatg aatctgggtg ttgtgacggt taatctgcct cgtattgctc ttgagtctga
    13261 aggtgatatg aataagttct gggaaatctt caacgagcga atgaatatcg cagaagatgc
    13321 tcttgtttac cgtgtcgaac gcactaaaga ggcgacacca gcaaatgctc ctattcttta
    13381 tcagtacggt gcttttggcc atcgtctagg taaagaagaa agtgttgacc agctctttaa
    13441 gaatcgtcgt gctaccgttt cgctgggcta tatcggcttg tatgaagtag cgacagtttt
    13501 ctttggtaac agctgggaaa gtaatccaga tgctaaggaa ttcacgctag acatcattca
    13561 cgatatgaaa cgccgtgtag aagagtggtc agaccaatat ggctaccatt tctctatcta
    13621 ctcaacacca tccgaaagtc tgacagaccg tttctgccga ctagatatag acaagtttgg
    13681 ctctattcct gatatcacag acaaggaata ctacaccaac tctttccact acgatgttcg
    13741 taaaaatcca acaccgtttg aaaaattgga ctttgagaaa gtctatccag aagcaggtgc
    13801 gtcaggtggt ttcatccatt attgtgagta tccagtcctt cagcaaaatc caaaggcctt
    13861 ggaagctgtc tgggattatg cttatgaccg tgtaggctat ctaggcacca atactccgat
    13921 tgaccgttgc tacaagtgtg actttgaagg ggattttgaa ccaactgaga gagggtttgc
    13981 ttgtccaaac tgtggcaata gcgatcctaa aacagtagac gttgttaaac ggacttgtgg
    14041 ctatcttggc aatcctcaag cgagaccaat ggttaacggg cgtcacaagg aaatcgctgc
    14101 gcgtgtcaaa catatgaatg gttcaacgat taaaatagct gggcatcaag taacaaatta
    14161 gaaagaaatg aaatgggaaa atatcaacta gacgataagg ggcgcgcaca agtgacccgt
    14221 tatcacgaga agcactctaa aggtggagct ggtaagaaag aacgcttgct tagcttcaga
    14281 gaacaatttt taaacaagaa caagaaaaaa taaaagtgag agccagctct cgcttttctc
    14341 atagtgggag gtagggatgg aattacgcag accaagatta gcggataaga aagctgtttt
    14401 agatatgatg acagagtttg aaaaatttca gtcgcctcac gacggcggtt tctgggatac
    14461 agagaacttt gtgtatgaag actggttaga aagcaatcag gaacaggaaa tggggattaa
    14521 tctgcctgaa ggatgggttc ctgcaattca gttagtggct ttttctgaga aaggtcaagc
    14581 agttggattt cttaatctcc ggttgcgcct cagtaacttt ttactagaag aaggtgggca
    14641 cattggctac tccatccgtc catctgaaag aggcaagggt tatgcaaaag agactctccg
    14701 tcagggcttg caagttgcta aggaaaagaa catcaagaaa gctctggtga cctgtagcgt
    14761 gaataatcct gctagcagag cagtcattct agcaaatggt ggaatatttg aggatgctcg
    14821 caatggagtc gagcgttatt ggatagaggt agcgaatgaa taatccaaaa ccacaagaat
    14881 ggaaaagcga ggaacttagt caaggtcgta tcattgacta caaggccttt aactttgttg
    14941 atggcgaagg cgtgcgtaac tctctctatg tatcaggctg tatgtttcac tgcgagggat
    15001 gttataatgt tgcgacttgg tcttttaatg ctggcattcc ctatacagca gaattagaag
    15061 agcagatcat ggcagacctt gcccaaccct atgttcaagg cttgactttg ctgggagggg
    15121 aaccttttct caatactggc attctcttgc ctctagttaa acgcatccga aaggaattgc
    15181 cagacaagga catttggtcc tggacgggct acacttggga agaaatgatg ttggaaactc
    15241 cagataaact ggaactctta tcattgattg acattcttgt cgatggaaga tatgatcgaa
    15301 ctaagagaaa tctcatgctc cagtttcgag gttcgtccaa ccaacgaatt atcgatgtgc
    15361 aaaaatcgct caaaagtggg caagtagtga tttgggacaa gctcaatgac ggaaaagaaa
    15421 gctatgaaca ggtgaagaga gaatgaagaa aaaagactta gtagaccaac tagtctcaga
    15481 gatcgagacg gggaaagtca ggacactggg aatatacggt catggagctt caggtaaatc
    15541 aacctttgca caggaattgt accaagcttt agattctact acagtaaatt tgctagagac
    15601 agatccttat atcacctcag gacgccatct ggtagtaccc aaggacgcgc cgaatcaaaa
    15661 ggtgacagcc agtctgccag tggcgcatga actggagagt ttgcagagag atatccttgc
    15721 cttgcaggcg ggtatggatg tcttgacaat tgaagaacct tggaaggcta gtgaggtctt
    15781 gtctggagcc aaaccaattt tgattgtcga agggatgtct gttggctttc tacccaagga
    15841 actctttgaa aaaaccatct gtttctacac ggatgaggag accgaattaa agcgacgcct
    15901 tgctagagat acgactgtga gaaatcgcga tgcatccttt atattggcta gccatcagat
    15961 gagacgggag cagtatctgc gatactataa agaaactgag tctaaggcgg atatcttagt
    16021 ggaccaatca gaagataaat ttgatgtcaa gaggacttaa cttatgtata gaagaaatat
    16081 agaagaaaat ccctaatttt agaaagaaaa agtaggaaaa cagtttcatc ccaaaaaaac
    16141 gaaaaaacag caacaaatcc cttgcaatcg caggggcttt gtgttattct attatggtgc
    16201 tgtaaattac agccttagtt ttgatgcaag aggttgcgac acgctcggtt gcattgccac
    16261 gcaacaccgc gtcggttttc ttgtggagct agcctattat cttaaataga cgaaaaggag
    16321 aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca ccgtacgctt
    16381 gacacagcgg ctgcaaaaat cgtagaatca gctactcgta caggtgcaca agttgcgggt
    16441 ccaatcccac ttccaactga acgtagcctc tacacaatca ttcgtgcgac tcacaaatac
    16501 aaagactctc gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga tatcgttaac
    16561 ccaactcaaa aaacagttga tgccttgatg aaattggatc ttccaagtgg tgtaaacgta
    16621 gaaatcaaac tttaatctaa aatataaaag agcagaggct ggtgtttcaa tctaattgaa
    16681 cacgggctaa actcggtgtg aaaaagataa acttcctagt gtctgctaga cactgcgtca
    16741 gtttcctatt ttcacgttga gtttgacgcc ctttgtatct tagacttgag cataaaaaac
    16801 gctcgttaaa aactttttga ataaaaaata tagaaaagga actattttct catgacaaaa
    16861 ggaatcttag ggaaaaaagt gggaatgact caaatcttca ctgaagctgg cgaattgatc
    16921 cctgtaacag ttattgaagc aactccaaac gttgttcttc aagttaaaac tgttgaaaca
    16981 gacggataca acgctatcca agttggtttc gatgacaaac gcgaagtatt gagcaacaaa
    17041 cctgctaaag gacatgtagc gaaagctaac acggctccta agcgcttcat tcgtgaattc
    17101 aaaaacgttg aaggcttgga agttggtgct gaaattacag ttgaaacatt cgcagctgga
    17161 gacgttgttg acgtaactgg tacttctaaa ggtaaaggtt tccaaggtgt tatcaaacgc
    17221 cacggacaat cacgtggacc aatggctcac ggttctcgtt accaccgtcg tccaggttct
    17281 atgggacctg ttgcacctaa ccgcgtattc aaaggtaaaa accttgcagg gcgtatgggt
    17341 ggcgaccgcg taacaattca aaaccttgaa gttgtacaag ttgttccaga aaagaacgtt
    17401 atccttatca aaggtaacgt accaggtgct aagaaatctc ttatcactat caaatcagca
    17461 gttaaagctg gtaaataata aagaaagggg aaatcagtca caatggcaaa cgtaacatta
    17521 tttgaccaaa ctggtaaaga agctggccaa gttgttctta gcgatgcagt atttggtatc
    17581 gaaccaaatg aatcagttgt gtttgatgta atcatcagcc aacgcgcaag ccttcgtcaa
    17641 ggaacacacg ctgttaaaaa ccgctctgca gtatcaggtg gtggacgcaa accatggcgt
    17701 caaaaaggaa ctggacgtgc tcgtcaaggt tctatccgct caccacaatg gcgtggtggt
    17761 ggtgttgtct tcggaccaac tccacgttca tacggctaca aacttccaca aaaagttcgt
    17821 cgcctagctc ttaaatcagt ttactctgaa aaagttgctg aaaacaaatt cgtagctgta
    17881 gacgctcttt catttacagc tccaaaaact gctgaatttg caaaagttct tgcagcattg
    17941 agcatcgatt ctaaagttct tgttatcctt gaagaaggaa atgaattcgc agctctttca
    18001 gctcgtaacc ttccaaacgt gaaagttgca actgctacaa ctgcaagtgt tcttgacatc
    18061 gcaaatagcg acaaacttct tgtcacacaa gcagctatct ctaaaatcga ggaggttctt
    18121 gcataatgaa tttgtatgat gttatcaaaa aacctgtcat cactgaaagc tcaatggctc
    18181 aacttgaagc agggaaatat gtatttgaag ttgacactcg tgcacacaaa cttttgatca
    18241 agcaagctgt tgaagctgct ttcgaaggtg ttaaagttgc caatgttaac acaatcaacg
    18301 taaaaccaaa agctaaacgt gttggacgtt acactggttt tactaacaaa actaaaaaag
    18361 ctatcatcac acttacagct gattctaaag caatcgagtt gtttgctgct gaagctgaat
    18421 aatctaagga ggaaatatcg tgggaattcg tgtttataaa ccaacaacaa acggtcgccg
    18481 taatatgact tctttggatt tcgctgaaat cacaacaagc actcctgaaa aatcattgct
    18541 tgttgcattg aagagcaagg ctggtcgtaa caacaacggt cgtatcacag ttcgtcacca
    18601 aggtggtgga cacaaacgtt tctaccgttt ggttgacttc aaacgtaata aagacaacgt
    18661 tgaagcagtt gttaaaacaa tcgagtacga tccaaaccgt tctgcaaaca tcgctcttgt
    18721 acactacact gacggtgtga aagcatacat catcgctcca aaaggtcttg aagtaggtca
    18781 acgtatcgtt tcaggtccag aagcagatat caaagtcgga aacgctcttc cacttgctaa
    18841 catcccagtt ggtactttga ttcacaacat cgagttgaaa ccaggtcgtg gtggtgaatt
    18901 ggtacgtgct gctggtgcat ctgctcaagt attgggttct gaaggtaaat acgttcttgt
    18961 tcgtcttcaa tcaggtgaag ttcgtatgat tcttggaact tgccgtgcta cagttggtgt
    19021 tgtcggaaac gaacaacatg gacttgtaaa ccttggtaaa gcaggacgta gccgttggaa
    19081 aggtatccgc ccaacagttc gtggttctgt aatgaaccct aacgatcacc cacacggtgg
    19141 tggtgaaggt aaggcaccag ttggtcgtaa agcaccatct actccatggg gcaaacctgc
    19201 tcttggtctt aaaactcgta acaagaaagc gaaatctgac aaacttatcg ttcgtcgtcg
    19261 caacgagaaa taatattaaa ctagtcgctt aagcaactag taaatccgcc agctcggtag
    19321 cgctccatag gagtgcaagc cgctgtggta caacatttaa aggagaaaat ataaaaatgg
    19381 gacgcagtct taaaaaagga cctttcgtcg atgagcattt gatgaaaaaa gttgaagctc
    19441 aagctaacga cgaaaagaaa aaagttatta aaacttggtc acgtcgatca acgatcttcc
    19501 caagtttcat tggttacact attgcagttt atgacggacg taaacacgta cctgtttaca
    19561 tccaagaaga catggtaggc cacaaacttg gtgaatttgc accaactcgt acttacaaag
    19621 gtcacgctgc agacgacaag aaaacacgta gaaaataagg agaacataaa tggcagaaat
    19681 tacttcagct aaagcaatgg ctcgtacagt acgtgtttca cctcgtaaat cacgtcttgt
    19741 tcttgataac atccgtggta aaagcgtagc cgatgcaatc gcaatcttga cattcactcc
    19801 aaacaaagct gctgaaatca tcttgaaagt tttgaactca gctgtagcta acgctgaaaa
    19861 caactttggt ttggataaag ctaacttggt agtatctgaa gcattcgcaa acgaaggacc
    19921 aactatgaaa cgtttccgtc cacgtgcgaa aggttcagct tcaccaatca acaaacgtac
    19981 agctcacatc actgtagctg ttgcagaaaa ataaggaggt aaaatcgtgg gtcaaaaagt
    20041 acatccaatt ggtatgcgtg tcggcatcat ccgtgattgg gatgccaaat ggtatgctga
    20101 aaaagaatac gcggattacc ttcatgaaga tcttgcaatc cgtaaattcg ttcaaaaaga
    20161 acttgctgac gcagcagttt caactattga aatcgaacgc gcagtaaaca aagttaacgt
    20221 ttcacttcac actgctaaac caggtatggt tatcggtaaa ggtggtgcta acgttgatgc
    20281 actccgtgca aaacttaaca aattgactgg aaaacaagta cacatcaaca tcatcgaaat
    20341 caaacaacct gatttggatg ctcaccttgt aggtgaagga attgctcgtc aattggagca
    20401 acgtgttgct ttccgtcgtg cacaaaaaca agcaatccaa cgtgcaatgc gtgctggagc
    20461 taaaggaatc aaaactcaag tatcaggtcg tttgaacggt gcagatatcg cccgtgctga
    20521 aggatactct gaaggaactg ttccgcttca cacacttcgt gcagatatcg attacgcttg
    20581 ggaagaagca gatactacat acggtaaact tggtgttaaa gtatggatct accgtggtga
    20641 agttcttcca gctcgtaaaa acactaaagg aggtaaataa ccaatgttag tacctaaacg
    20701 tgttaaacac cgtcgtgaat tccgtggaaa aatgcgcggt gaagcaaaag gtggaaaaga
    20761 agtagcattc ggtgaatacg gtcttcaagc tacaactagc cactggatca ctaaccgcca
    20821 aatcgaagct gctcgtatcg ccatgactcg ttacatgaaa cgtggtggta aagtttggat
    20881 taaaatcttc ccacacaaat catacactgc taaagctatc ggtgtgcgta tgggatctgg
    20941 taaaggggca cctgaaggtt gggtagcacc agttaaacgt ggtaaagtga tgttcgaaat
    21001 cgctggtgta tctgaagaga ttgcacgtga agcgcttcga cttgctagcc acaaattgcc
    21061 agttaaatgt aaattcgtaa aacgtgaagc agaataagga gaaggcatga aacttaatga
    21121 agtaaaagaa tttgttaaag aacttcgtgg tctttctcaa gaagaactcg cgaagcgcga
    21181 aaacgaattg aaaaaagaat tgtttgaact tcgtttccaa gctgctactg gtcaattgga
    21241 acaaacagct cgcttgaaag aagttaaaaa acaaatcgct cgtatcaaaa cagttcaatc
    21301 tgaagcgaaa taatagacta gggaaggaga aatttcaatg gaacgcaata atcgtaaagt
    21361 tcttgttgga cgtgttgtat ctgacaaaat ggacaagaca atcacagttg tagttgaaac
    21421 aaaacgtaac cacccagtct atggtaaacg tattaactac tctaaaaaat acaaagctca
    21481 tgatgaaaac aatgttgcca aagaaggcga tatcgtacgt atcatggaaa ctcgcccgct
    21541 ttcagctaca aaacgtttcc gtcttgtaga agttgttgaa gaagcggtca tcatctaatc
    21601 aaacctgaaa ggagaaaact gaaatgattc aaacagaaac tcgtttgaaa gtcgcagaca
    21661 acagcggtgc tcgcgaaatc ttgactatca aagttcttgg tggttcagga cgtaaatttg
    21721 caaacatcgg tgatgttatc gtggcatctg taaaacaagc tactcctggt ggtgcggtta
    21781 aaaaaggtga cgttgttaaa gcagttatcg ttcgtactaa atcaggtgct cgtcgtgctg
    21841 atggttcata catcaaattt gacgaaaacg cagcagttat catccgtgaa gacaaaactc
    21901 ctcgcggaac acgtatcttt ggcccagttg cacgtgaatt gcgtgaaggt ggcttcatga
    21961 agatcgtgtc acttgctcca gaagtacttt aatttttagg aacaaactag tcccctagct
    22021 tcaagctagg gtgcccttat gggcgtaaga aaaatcaagg agaaacctaa tgtttgtaaa
    22081 aaaaggcgac aaagttcgcg taatcgctgg taaagataag ggaacagaag ctgttgtcct
    22141 tactgccctt ccaaaagtaa acaaagttat cgttgaaggt gttaacattg ttaagaaaca
    22201 ccaacgtcca actaacgagc ttcctcaagg tggtatcatc gagaaagaag cagctatcca
    22261 cgtatcaaac gttcaagttt tggacaaaaa tggtgtagct ggtcgtgttg gttacaaatt
    22321 tgtagacggt aaaaaagttc gctacaacaa aaaatcaggc gaagtgcttg attaatcacg
    22381 aaggaaagga gaagtataat ggcaaatcgt ttaaaagaaa aatatcttaa tgaagtagtt
    22441 cctgctttga cagaacaatt caactactca tcagtgatgg ctgtgcctaa agtagataag
    22501 attgttttga acatgggtgt tggtgaagct gtatcaaacg ctaaaagcct tgaaaaagct
    22561 gctgaagaat tggcacttat ctcaggtcaa aaaccactta tcactaaagc taaaaaatca
    22621 atcgccggct tccgtcttcg tgaaggtgtt gcgatcggtg caaaagttac ccttcgtggt
    22681 gaacgtatgt acgaattctt ggataaattg gtatcagttt cacttccacg tgtacgtgac
    22741 ttccacggtg ttccaacaaa atcatttgat ggacgcggga actacacact tggtgtgaaa
    22801 gaacaattaa tcttcccaga aatcaacttc gatgacgttg acaaaactcg tggtcttgac
    22861 atcgttatcg taacaactgc taacactgac gaagagtcac gtgcattgct tacaggcctt
    22921 ggaatgcctt ttgcaaaata atataggagg taaatctaat ggctaaaaaa tcaatggtag
    22981 ctagagaggc taaacgccaa aaaattgttg accgttatgc tgaaaaacgt gctgcattaa
    23041 aggcggcagg ggactacgaa ggtttatcta aattacctcg caacgcctca ccgactcgtt
    23101 tacataatcg ttgtagagtt acggggcgcc cacattcagt ttaccgcaaa tttggtctga
    23161 gtcgtatcgc ttttcgcgaa cttgcgcata aaggtcaaat tcctggtgta acaaaagcat
    23221 cttggtaatt taagatatca agagcgtcaa aactccaagt aaaaatagga aacttgacga
    23281 agaaactaaa gtttctagga aagtttatct ttttcacaca gagtttagcc cgggttcaat
    23341 tgggcttgcc aatttgaaca cgagctacag ctttggaaaa aaagaccaat ttgctttgga
    23401 gcattgcttt tgcattaaat tgtctatttt tgctcgtgct gttacgctct ttgtatcatg
    23461 tattaactag caagtgcaac ttgcaaacta ctagtaagag gagaaaaaca aaatggttat
    23521 gactgaccca atcgcagact tcctaactcg tattcgtaat gctaaccaag ctaaacacga
    23581 agtacttgaa gtacctgcat caaacatcaa aaaagggatt gctgaaatcc ttaaacgcga
    23641 aggttttgta aaaaacgttg aaatcattga agatgacaaa caaggcgtca tccgtgtatt
    23701 tcttaaatac ggaccaaatg gtgagaaagt tatcactaac ttgaaacgtg tttctaaacc
    23761 aggacttcgt gtctacaaaa aacgtgaaga ccttccaaaa gttcttaacg gacttggaat
    23821 tgccatcctt tcaacttctg aaggtttgct tactgataaa gaagcacgcc aaaagaatgt
    23881 tggtggtgag gttatcgctt acgtttggta aaatcaagat acaaagctcg taaagaacaa
    23941 agcaaaatta ggaagttgga gaagtttgtt tacaaacaag ccaacttatc tattttgcac
    24001 agttcttaga gcgtgttcag ttcagctctt gaactaaata agtatctgaa ccccgtgaaa
    24061 actggccgtt ctggcctgac aatttaacag gagaaaataa acatgtcacg tattggtaat
    24121 aaagttatcg tgttgtctgc tggtgttgaa ctcgctaaca atgacaacgt tgtaactgta
    24181 aaaggaccta aaggagaact tactcgtgag ttctcaaaag atattgaaat ccgtgtggaa
    24241 ggtactgaaa taactcttca ccgtccaaac gattcaaaag aaatgaaaac tatccacgga
    24301 actactcgtg cccttttgaa caacatggtt gttggtgtat cagaaggatt caagaaagaa
    24361 cttgaaatgc gtggggttgg ttaccgtgca cagcttcaag gatctaaact tgttttggct
    24421 gttggtaaat ctcatccaga cgaagttgaa gctccagaag gaattacttt tgaacttcca
    24481 aacccaacaa caatcgttgt tagcggaatt tcaaaagaag tagttggtca aacagctgct
    24541 tacgtacgta gccttcgttc accagaacca tataaaggta aaggtatccg ttacgttggt
    24601 gaattcgttc gccgtaaaga aggtaaaaca ggtaaataat gttgagtggt tgatcatcaa
    24661 ccaccaacct attttccaac tttgtgcata gcacacgatt taaaactaaa gaggtgaaaa
    24721 ctgtgatttc aaaaccagat aaaaacaaac tccgccaaaa acgccaccgt cgcgttcgcg
    24781 gaaaactctc tggaactgct gatcgcccac gtttgaacgt attccgttct aatacaggca
    24841 tctacgctca agtgattgat gacgtagcgg gtgtaacgct cgcaagtgct tcaactcttg
    24901 ataaagaagt ttcaaaagga actaaaactg aacaagccgt tgctgtcggt aaactcgttg
    24961 cagaacgtgc aaacgctaaa ggtatttcag aagtggtgtt cgaccgcggt ggatatctat
    25021 atcacggacg tgtgaaagct ttggctgatg cagctcgtga aaacggattg aaattctaat
    25081 aggaggacac tagaaaatgg catttaaaga caatgcagtt gaattagaag aacgcgtagt
    25141 tgctgtcaac cgtgttacaa aagttgttaa aggtggacgt cgtcttcgtt tcgcagctct
    25201 tgttgttgtt ggtgaccaca atggtcgcgt aggatttggt actggtaaag ctcaagaagt
    25261 tccagaagca atccgtaaag cagtagatga tgctaagaaa aacttgatcg aagttcctat
    25321 ggttggaaca acaatcccac acgaagttct ttcagaattc ggtggagcta aagtattgtt
    25381 gaaacctgct gtagaaggtt ctggagttgc cgctggtggt gcagttcgtg ccgttgtgga
    25441 attggcaggt gtggcagata ttacatctaa atcacttggt tctaacactc caatcaacat
    25501 tgttcgtgca actgttgaag gtttgaaaca attgaaacgc gctgaagaaa ttgctgccct
    25561 tcgtggtatt tcagtttctg atttggcata agaaagggga taaaatggct caaattaaaa
    25621 ttactttgac taagtctcca atcggacgca ttccatcaca acgtaaaact gttgtagcac
    25681 ttggacttgg caaattgaac agctctgtta ttaaagaaga taacgctgct atccgtggta
    25741 tgatcacagc agtatctcac ttagtaacag ttgaagaagt aaactaatga agttttaggg
    25801 gatgtgcact gtaccatccc ctaaaactag atatagtcat ctatgatgac atcgtatagg
    25861 cgagttgatg ggggagacaa ccttttctcc cttatcggcg ctagcatttt acaaaagagg
    25921 agaaaataaa aatgaaactt catgaattga aacctgcaga aggttctcgt aaagtacgta
    25981 accgcgttgg tcgtggtact tcatcaggta acggtaaaac atctggtcgt ggtcaaaaag
    26041 gtcaaaaagc tcgtagcggt ggcggagttc gccttggttt tgaaggtgga caaactccat
    26101 tgttccgtcg tcttccaaaa cgtggattca ctaacatcaa cgctaaagaa tacgcaattg
    26161 tgaaccttga ccaattgaac gtctttgaag atggtgctga agtaactcca gttgttctta
    26221 tcgaagcagg aattgttaaa gctgaaaagt caggtattaa aattcttggt aacggtgagt
    26281 tgactaagaa attgactgtg aaagcagcta aattctctaa atcagctgaa gaagctatca
    26341 ctgctaaagg tggttcagta gaagtcatct aagagaggtg acctatgttt tttaaattat
    26401 taagagaagc tcttaaagtc aagcaggttc gatcaaaaat tttatttaca atttttatcg
    26461 ttttggtctt tcgtatcgga actagcatta cagttcctgg tgtgaatgcc aatagcttga
    26521 atgctttaag tggattatcc ttcttaaaca tgttgagctt ggtgtcgggg aatgccctaa
    26581 aaaacttttc gatttttgcc ctaggagtta gtccctatat caccgcttct attgttgtcc
    26641 aactcttgca aatggatatt ttacccaagt ttgtagagtg gggtaaacaa ggggaagtag
    26701 gtcgaagaaa attgaatcaa gctactcgtt atattgctct agttctcgct tttgtgcaat
    26761 ctatcgggat tacagctggt tttaatacct tggctggagc tcaattgatt aaaactgctt
    26821 taactccaca agtttttctg acgattggta tcatcttaac agctggtagt atgattgtca
    26881 cttggttggg tgagcaaatt acagataagg gatacggaaa cggtgtttcc atgattatct
    26941 ttgccgggat tgtttcctca attccagaga tgattcaggg catctatgtg gactactttg
    27001 tgaacgtccc aagtagccgt atcacttcat ctatcatttt cgtaatcatt ttgattatta
    27061 ctgtattgtt gattatttac tttacaactt atgttcaaca agcagaatac aaaattccaa
    27121 tccaatatac taaggttgca caaggtgctc catctagctc ttaccttccg ttaaaggtaa
    27181 accctgctgg agttatccct gttatctttg ccagttcgat tactgcagcg cctgcggcca
    27241 ttcttcagtt tttgagtgcc acaggtcatg attgggcttg ggtaagggta gcacaagaga
    27301 tgttggcaac tacttctcca actggtattg ccatgtatgc tttgttgatt attctcttta
    27361 cattcttcta tacgtttgta cagattaatc ctgaaaaagc agcagagagc ctacaaaaga
    27421 gtggtgccta tatccatgga gttcgtcctg gtaaaggtac agaagaatat atgtctaaac
    27481 ttcttcgtcg tcttgcaact gttggttccc tcttccttgg tgtgatttcc attttaccga
    27541 ttgcagctaa agatgtattt ggtctttctg atgttgttgc ctttggtgga acaagtctct
    27601 tgatcattat ctctacaggt atcgaaggaa tcaagcaatt ggaaggttac ctattgaaac
    27661 gtaagtatgt tggtttcatg gacaaaacag aataaaagta tttactgaat cagtaaatac
    27721 tgagggagtg gaggtttaaa ctctgacatt tgtaagagtt ggatctcccc tcttctattt
    27781 tgtttttaaa taggggtgaa aagacttttt gcttctattt aaaaataaaa taaggagatc
    27841 aaatcatgaa tcttttgatt atgggcttac ctggtgcagg taagggaact caagcagcaa
    27901 aaatcgtaga acaattccat gttgcacata tctcaacagg tgatatgttc cgcgctgcaa
    27961 tggtaaatca aactgaaatg ggtgttcttg ctaagtcata tattgacaag ggtgaattgg
    28021 ttcctgacga agttacaaat ggaatcgtaa aagaaggtct ttcacaagat gatattaaag
    28081 aaacaggatt cttattggat ggttacccac gtacaattga acaagctcat gccttggaca
    28141 aaacattggc taaacttggc attgaactag aaggtgttat caatattgaa gtgaaccctg
    28201 acagcctctt ggaacgtttg agtggccgta tcatccaccg cgtaactgga gaaactttcc
    28261 acaaggtctt taacccacca gttgactata aagaagaaga ctactaccaa cgtgaagatg
    28321 ataagcctga gacagtaaaa cgtcgtttgg atgttaatat tgctcaagga gaaccaatca
    28381 ttgctcacta ccgtgccaaa ggtttggttc atgacatcga aggtaatcaa gatatcaatg
    28441 atgtcttctc agatattgaa aaagtattga caaatttgaa ataaagcgtt tttcacactt
    28501 gcaaaaatcc gctacaaatg ttatactgag atagtctgac ttataattgt tgtctctgtg
    28561 tctagaggca tcgaatcgaa atttatggag gtgcttttgc gtggcaaaag acgatgtgat
    28621 tgaagttgaa ggcaaagtag ttgatacaat gccgaatgca atgtttacgg ttgaacttga
    28681 aaatggacat cagattttag caacagtttc tggtaaaatt cgtaaaaact atattcgtat
    28741 tttagcggga gatcgtgtta ctgtcgaaat gagtccatat gacttgacac gtggacgtat
    28801 cacttaccgc tttaaataat cgaaaaactt ggagggataa gaaatgaaag taagaccatc
    28861 ggtcaaacca atttgcgaat actgtaaagt tattcgtcgt aatggtcgtg ttatggtaat
    28921 ttgcccagca aatccaaaac acaaacaacg tcaaggataa gatagaaagg agaaaacatg
    28981 gctcgtattg ctggagttga tattccaaat gacaaacgcg tagtaatctc attgacttat
    29041 gtttatggta tcggacttgc aacatctaag aaaattttgg ctgctgctgg aatctcagaa
    29101 gatgttcgtg tacgtgatct tacatcagat caagaagatg ctatccgtcg tgaagtggat
    29161 gcaatcaaag ttgaaggtga ccttcgtcgt gaagtaaact tgaacatcaa acgtttgatg
    29221 gaaatcggtt cataccgtgg tatccgtcac cgtcgtggac ttcctgtccg tggacaaaat
    29281 actaaaaaca acgctcgcac tcgtaaaggt aaagctgttg cgattgctgg taagaaaaaa
    29341 taatatagga ggtaaaagtc ttggctaaac caacacgtaa acgtcgtgtg aaaaagaata
    29401 tcgaatctgg tattgctcat attcacgcta catttaataa cactattgtt atgattactg
    29461 atgtgcatgg taatgcaatt gcttggtcat cagctggtgc tcttggtttc aaaggttctc
    29521 gtaaatctac accattcgct gctcaaatgg cttctgaagc tgctgctaaa tctgcacaag
    29581 aacacggtct taaatcagtt gaagttactg taaaaggtcc aggttctggt cgtgagtcag
    29641 ctattcgtgc gcttgctgcc gctggtcttg aagtaacagc aattcgtgat gtgactccag
    29701 tgccacacaa tggtgctcgt cctccaaaac gtcgccgtgt ataatcatcg cattacactg
    29761 cttttcgttt aagagggagt aactaaatga tcgagtttga aaaaccaaat ataacaaaaa
    29821 ttgatgaaaa taaagattat ggcaagtttg taatcgaacc acttgaacgt ggctacggta
    29881 caactcttgg taactctctt cgtcgtgtac ttctagcttc tctaccagga gcagctgtga
    29941 catctatcaa cattgatggt gtgttacatg agtttgacac agttccaggt gttcgtgaag
    30001 acgtgatgca aatcattctg aacattaaag gaattgcagt gaaatcgtac gttgaagacg
    30061 aaaaaatcat cgaactggat gttgaaggtc ctgctgaagt aacagctggt gacattttga
    30121 cagatagcga tattgaaatt gtaaatccag atcattatct ctttacaatc ggtgaaggtt
    30181 cttctctaaa agcgactatg actgttaaca gtggtcgtgg atatgtacct gctgacgaaa
    30241 ataaaaagga taatgcacca gttggaacac ttgctgtaga ttctatttat acaccagtta
    30301 caaaagtcaa ctatcaagtg gaacctgctc gtgtaggtag caatgatggt ttcgacaaat
    30361 taacccttga aatcttgaca aatggaacaa ttattccaga agatgcttta gggctttcag
    30421 cacgtatttt gacagaacat cttgatttgt ttacaaatct tactgagatt gctaagtcaa
    30481 ctgaagtgat gaaagaagct gatactgaat ctgacgaccg tattttagat cgtacgattg
    30541 aggaactgga cttgtctgtg cgttcataca actgtttaaa acgtgccggt atcaatactg
    30601 tgcatgattt gacagaaaaa tctgaagcag agatgatgaa agtacgaaat cttggacgca
    30661 agagtttgga agaagtgaaa ctcaaactca ttgatttggg tcttggatta aaagataaat
    30721 aaaggaggaa tacatggctt accgtaaact aggacgcact agctcacaac gtaaagcaat
    30781 gcttcgcgat ttgacaactg accttttgat caacgaatca atcgtgacaa ctgaagctcg
    30841 tgctaaagaa atccgtaaaa ctgttgaaaa aatgattact ctaggtaaac gtggtgattt
    30901 gcatgcacgt cgtcaagcag ctgctttcgt acgtaatgaa atcgcatctg aaaactatga
    30961 tgaagcaact gataagtaca cttctactac agcacttcaa aaattgttct cagaaatcgc
    31021 acctcgttat gctgaacgta acggtggata cactcgtatc cttaaaactg aaccacgtcg
    31081 tggtgatgca gcgccaatgg cgatcatcga attagtataa aatcatcaat tttgttgagt
    31141 gttatgatga tggagtcttg tgctcttagt ctagctctgg tctaccgcta ggatttcggt
    31201 cctagcggga acactcatca taagttggga tagtagacgc ttgtttacga aattgttttt
    31261 ttcttaagaa caacttcgta agcaggcgtt tttgagtatt ttcgttagaa ttatgctata
    31321 ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat tttaagaaga attggagttt
    31381 acttatgaaa gccattataa ctgttgttgg taaagataaa tctggaattg ttgcaggtgt
    31441 ttctggtaaa attgcagaat taggattgaa tattgacgat atctctcaaa ctgtattgga
    31501 tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa aagcaagatt ttacctatct
    31561 tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta aaaatcaata ttcagagtgc
    31621 agcgattttc gaagctatgt ataatatcta ggaggtcatc atggatatta gacaagttac
    31681 tgaaaccatc gccatgattg aggagcaaaa cttcgatatt agaaccatta ccatggggat
    31741 ttctcttttg gactgtatcg atccaaatat caatcgtgct gcggagaaaa tctatcaaaa
    31801 aattacgaca aaggcggcta atttagtagc tgttggtgat gaaattgcgg ctgagttggg
    31861 aattcctatc gttaataagc gtgtatcggt gacacctatt tctctgattg gggcagcgac
    31921 agatgcgacg gactacgtgg ttctggcaaa agcgcttgat aaggctgcga aagagattgg
    31981 tgtggacttt attggtggtt tttctgcctt agtacaaaaa ggttatcaaa agggagatga
    32041 gattctcatc aattccattc ctcgcgcttt ggctgagacg gataaggtct gctcgtcagt
    32101 caatatcggc tcaaccaagt ctggtattaa tatgacggct gtggcagata tgggacgaat
    32161 tatcaaggaa acagcaaatc tttcagatat gggagtggcc aagttggttg tattcgctaa
    32221 tgctgttgag gacaatccat ttatggcggg tgcctttcat ggtgttgggg aagcagatgt
    32281 tatcatcaat gtcggagttt ctggtcctgg tgtggtgaaa cgtgctttgg aaaaagttcg
    32341 tggacagagc tttgatgtag tagccgaaac agttaagaaa actgccttta aaatcactcg
    32401 tatcggtcaa ttggttggtc aaatggccag tgagagactg ggtgtggagt ttggtattgt
    32461 ggacttgagt ttggcaccaa cccctgcggt tggagactct gtggcacgtg tccttgagga
    32521 aatggggcta gaaacagttg gcacgcatgg aacgacagct gccttggccc tcttgaacga
    32581 ccaagttaaa aagggtggag tgatggcctg taaccaggtc ggtggtctat ctggtgcctt
    32641 tatccctgtt tctgaggatg aaggaatgat tgctgcagtg caaaatggct ctcttaattt
    32701 agaaaaacta gaagctatga cggctatctg ttctgttgga ttggatatga ttgccatccc
    32761 agaagatacg cctgctgaaa ctattgcggc tatgattgcg gatgaagcag caatcggtgt
    32821 tatcaacatg aaaacaacag ctgttcgtat cattcccaaa ggaagagaag gcgatatgat
    32881 tgagtttggt ggtctattag gaactgcacc tgttatgaag gttaatgggg cttcgtctgt
    32941 cgacttcatc tctcgcggtg gacaaatccc agcaccaatt catagtttta aaaattaaga
    33001 aaataggaga aattttaagt tctatttaag attagacgtg tatactataa tcattaaata
    33061 aagacctcct aatattattt gaaacagata acactgaatt agtttgaatt tgattttcat
    33121 ctaatatctt tatttaatga actcctaaac tttttcataa taatctcctt caaaagtcgc
    33181 ctgtatgggt ggcttttatt ttatcattca tgatataata gaagcaaacg gaggacggaa
    33241 aatggtaaaa gtacgattgt atttggtacg tcatggcaag accatgttta acacgattgg
    33301 tcgcgcgcaa ggttggagcg atactccctt aactgctgaa ggtgaacgag ggattcaaga
    33361 gttaggaatt ggtttgcgag aatctgatct acagtttgag cgcgcttatt cgagtgattc
    33421 tggtcgtacc attcagacca tgggaattat ccttgaagaa cttggcttgc aggggaaaat
    33481 cccttatcgc atggacaagc gtatcagaga atggtgtttc ggtagttttg atggagccta
    33541 tgatggcgat cttttcatgg gcattattcc tcgtatcttt aatgtggacc acgttcacca
    33601 attgtcttat gctgaactgg ctgagggctt ggtagaggtc gatacagctg gttgggctga
    33661 aggctgggaa aaactcagtg gccgaatcaa ggaaggcttt gaaatgattg caaaagaaat
    33721 ggaagatcaa ggtggaggta acgcccttgt tgtcagccat ggaatgacta ttggaaccat
    33781 tgtttatctg attaatggca tgcatccgca tggtctagat aatggtagcg tgacgattct
    33841 tgaatatgag gacggtcagt ttagggttga agttgtcggt gaccgtagtt accgagagct
    33901 aggacgtgag aagatggaag aaggctctat ttaatcagtc tagacttgct tgccatgagc
    33961 tagggatttg ataagaatat caagataaga aaaaacagcc gagggtactc ctttcggctg
    34021 tttttgatgt ggaaaactaa agtgtaatgc tattgctttt agagattttc ataaacaaga
    34081 gcaaggaacc tactgttaga acagtcagga tagttgacaa ggctgcggct acaccgtaat
    34141 ttcctctgag aacctctgta taaatagcta cagtcattgt tcttgttttg acattgtaga
    34201 ggaggataga agtagagagt tttgaaatca ttgtgaccca agataagatg gctccagaaa
    34261 tgataccaga tagcatcatt ggagttgtaa tcttagcaaa ggtattgaga cgactacttc
    34321 ctaagctttc agcagcttct tcaatacttg gtgctatttg ttgtaagcta gcaacagatg
    34381 agcgaatagt ataaggtaat cttctgacag atagagacat aatcaagatg aaagcagtcc
    34441 ctgtaatcat aagaaatcca cttccaaata gaccagtatt gaaggaagaa atgaaggcaa
    34501 tccctagaac ggttcctggt acaatataag gtaccatact gaggctgtca attaagtttg
    34561 taaacaaatt ccgttttcta acggctaggt aggagataaa tgtcgcaaat agaacaacta
    34621 gaactaaggc aatcaaaggg atacgaatgg tattgaaaat agcagatccc atacgatgga
    34681 aagctacctt gtaactgttt ggagaataac ctttaacaga taccatacct gatgttttta
    34741 ggaaagaggt ataaattaag tagatttgag gtaaaacaga gataaagata attccgtaga
    34801 ctgttgcata aatggcagct atttttcctt ttgtagtttt tttaggctca attggatgga
    34861 gcagattcat gctgaaactg tagcggtttg caatgtgttt ttggataagg aaaattgcca
    34921 aggcaatgat aatcgccata attgcaaaag cagaatttcc tccaacctcg ctaataaatt
    34981 gggtataaat caggacaggg aaagtccgat atccttcgcc aatcaacata ggcgttccaa
    35041 agtctgagaa tgctctcata aatacaagca aggagctgct agtaaggttg gaactaggag
    35101 aggtaaaaca accgttacga tacgcttaaa tccgaaggac cccatgcttt cagctgcttc
    35161 aagtagagaa ttgtcaatac tgttcattgt tccagcaaca tatagaaata ccagtgggaa
    35221 tagttgcagt gtaaagacaa gtacaattcc tttgaatcca taaatatcga tagctggaag
    35281 atgaagggca tttgtcaaaa atttagtgat gacctcattt cgtcccagca agagaatcca
    35341 ggagtaggct cctacgaaag gagctgacat ggaagcaatg ataatcaata tttgtaggaa
    35401 tttcttcccc ttgaagtcat acatagagaa gagataagct aatagggttc ctacaactaa
    35461 ggaagtgaca gtagcggtaa tggaaaccct gaaactgttg actagtgtct cagagtagta
    35521 ggttttacta aagaaagtga caaaattagc tagtgagaat tatccttcat gtataagtgc
    35581 ttacttgagc acggtaacga taggataaac gagaaagaca agataggtaa gaaagatgaa
    35641 gaaagaggag gctgtccaaa tatttagttt tttacattcc atggttgact ccttttatca
    35701 ggttttggga accatctgca gaaaagatgt ttcatttttg tgtattgatt cgtagacgaa
    35761 tacgattgtc tttttgtaga tcttcttcaa aagttgattc ttcactaact tgaatttttg
    35821 aggcaaaacc tgtctcaatg aaatactccg tatttagtcc aagatagacg ctatcgctaa
    35881 tagttccttc gatatctcca gattcatctt tgataaactc ttcgggacga atgcttacat
    35941 gaatagcttg ctcctcaacc tgatcaagag ctggtattcg aagggcatag ccatctgaaa
    36001 agacgatata agcgccgtcg ctccgttttt caagattggc agggataata tttgtgcgtc
    36061 cgataaaggt tgctacaaac tcattagctg gtttatgata gagttctttt ggtcggccga
    36121 tttgttggat caccccatct ttcataacag caatttgatc tgaaatagcc atggcttctt
    36181 cttggtcgtg ggttacataa acagttgtaa ttcccacttc gtgttggatt tctcggatgg
    36241 cttgacgcat atccaagcga agtttggcct ccagattact aagtggctcg tccatgagga
    36301 gaacacttgg attaaccgct aaggcgcatg ccaaggtgac acgttgttgt tgtccaccac
    36361 tgagtttatc gggctttcat ccgcatattg agcaatttgc atgagttcaa gatacttgtt
    36421 ggtctgttga atcaattctt cttttggaac cttcttttgc ataagaccaa aagcaacgtt
    36481 gtctcggaca gtcaaatgtg ggaaaatagc gtagttttgg aaaaccatcc cgatattgcg
    36541 tttgctgggt tccatattat tgatttttgt atcatcgaag taaaattctc catctttgat
    36601 actgttgaaa cctgcaatca tacgaagaag ggtcgttttc ccacatcctg aaggtccaag
    36661 aagggtaaag agacttcctt ttggaattgt aatgttcaaa ttctcaataa cagggacatc
    36721 gtggtagatt ttttggcgtt aataattttg atctcactca tagtgaacct tttttactgt
    36781 ttagattgga tatctgtaaa gacttcgttg tatttcttaa cgatatctga tttattcttg
    36841 atgacataat cataatcttc agtgagtgtt ttgattttgt caattggttt catgttttcg
    36901 cttgttttag catttttacg aacaggacgg ttagtagtgg ttgtaccaag tgtatcttgt
    36961 acttcttgag agataataaa atcgataaat ttcttggcat tttccatatt tttagatttt
    37021 ttaacgatag cagcactagc aggtaggaag acggttcctt cttttggata gactacctta
    37081 atgttagctc cgtcatttaa gagcttaact gctggatctt cataagagag accaacagtc
    37141 atttctccat cagcgactgc tttatagaca ccagatgaac ttaaaccgat tttaccatca
    37201 ataagtgtga aaagatcttt tacataagac caagccttat catctttgta accaccttga
    37261 gcttgtagca tatttgttaa ttgagcaaag gcgctagaag agtttgctgg gtcagcagtt
    37321 gcgatttttc cttttagttc aggtttgaga agaacgttat atccttcgat gttcatgcct
    37381 ttagttaaat cagggttgac gattaaaaca ctaccatcta gtgtataagg agtagagtag
    37441 ccagttgtgt tttgatattc tttgataaca ttatcatttt cttttgaagt atagttttca
    37501 aagagttctc cgtgggtagc atattgtgta taagaaccac caaagataac atcagctaca
    37561 ggaacttctt tttctgactc tagttttttg aaaagttctc cagtaccagc ttgaatcagt
    37621 tctattttga taccatattt ttcttcaaag gcaggaatag ttgctccaat taagccttct
    37681 gagtttggtc aataaacgac tagcgaacca ccgtctcctt tatcagatga actgtcatcg
    37741 gcagattcat tagaagaaca agcagcataa tacatccatt tctttttcat gatggatacc
    37801 tccgttgtgt tatttaagtt tattttaaaa caatgtaagc gtttttaaaa cctacaattc
    37861 tattctatag tgtattgaat ctataacagt acactttgac tgctaaaata tttctataaa
    37921 ttaatttgac tttcctgata gagatgttca catcttattt caattcacta tattagagta
    37981 aaattctcta caaaaagaag aatagcctat tttactattc ttccgagtaa tttcaattcc
    38041 tttggggaaa tatggagatg ctttttaaat actttggcaa aatatttata gtctgaaaat
    38101 ccaacttggt cagagatagc gcttaaaggg gagttgggag attcagccat cttatctata
    38161 gcttgtttca ggcgatattg taagatatat tcatttagag tcatctttga taaccttata
    38221 tagatagctt tcgttatagt ttaaagcttc agcaatagta atgctctgca tagtgcttgt
    38281 ggacaaagga gataatttgt tgaatgattt ggttttgtgt atcaacctgt tggatagagg
    38341 tgagtaaagt ttgatattct tctaaaaaag gagtttcttg agatgtgcta atttgtaatc
    38401 gcaaaacaat tttttgaaga cattctgtca attccttggt atcaattggc ttggataaga
    38461 aatcaactgc tccatattgc atggcttttt ggcattttga aaatcgttat aacctgataa
    38521 gataactttt tcataagaaa gagtacgagt ggctttgaac atcataaaag catccataat
    38581 tggcattgtg atgtctgtta agacaaatat gagtttcttt ttcttggatg agtttcattc
    38641 cttcttgacc gtgactggca gttcctacga cttggatgcc taaggcagag tagtctacgg
    38701 caatctctag ccattttcgg atgaggtgtt catcttctac aataatgagc ttaaacatga
    38761 gttagtcttt cgttacaaat ttgacccaag tttctccttg gcgattgact cctaaatcta
    38821 gctggacatc agaaaagaaa ttgctcaatt gtttgtagct gttcatgatg ccatgctggg
    38881 tatgagggct ttctaaagag tctaaaatag cgaatcgctc ttgtttggtg agtcctccag
    38941 cattatcctt gactaaaaaa gttagagaat ctgcttccaa ggtaatgtgg atatcaatat
    39001 gaagatcaat acggtattgc atcccatgtt ttatagcatt ttctactaga ggaagcaaga
    39061 aaagtttagg gataggctga ttatcgacag tttctgggca gacaatatca taggaaaagt
    39121 gctcgaaacg aatcttatga atcataaggt aatcctctat aatctttaaa tcctgacaaa
    39181 tggttgtttc tttttctaaa tcggtgatac tgtatcggag aatgcgcgtg aggtcacaaa
    39241 ggctgcgata gagcttctat ggagaatttc tttttggaga gattttttaa aggaatgaga
    39301 catccgctac ctcattggaa ggtttttttg tgataagtat agcagtttaa aaattctaga
    39361 gcaaggtaaa atagaaaagg tttggctaaa attttttagc taaacctttt gaaaagttaa
    39421 gtatgtatta tagatgcttg ttatctgcaa atagctagag catttcaagg aaatgaacta
    39481 gaaataacaa ttaatatggt ggttcagaaa taccttttga taatcaataa gatcttcagg
    39541 atgaagtgcg ttgattccat ccatttcata tttccgattt aataaacgat atttgttttc
    39601 accaaattga tgaaaaggga gtagttgaac ttggtcgata tttaatgagt taaatagagt
    39661 agcgaatttt tctgcatcct ctaaactatt gttaaaatta ggaataactg ggattcttaa
    39721 aacgatagtt ttattttgag aaaaagcata atgaatgttt ttaataatca tttgattaaa
    39781 aaccccagtc acttttttat gttttataga gttataatgt tttaggtctg tgtagataaa
    39841 atccacatat tgaattaaat cgataaattt ttcatgatca acaaaggcag tagtttcaat
    39901 ggcagtgtgt atgtgatgtt ctttagctga ttttaagatg gctttagcaa attcaaactg
    39961 agcaaatatt tcacctcctg ataaagttaa acctccaccg gattcttcgt aaaattcttt
    40021 gtcttttaat acctctgtaa taatttcttc tacagtcttt tcttcaccga ctaaggtgaa
    40081 tttctctcgt tgagcatctt tcattttttc aggtttcatt ctttgagatt caggattaga
    40141 acaccatgga cagcgcagag gacatccttt taaaaaaaca gttgtacgaa tacccgggcc
    40201 gtcatgaatt gaaaagtgtt gaatattaaa aataattcct ttagatattt ccataagagt
    40261 tcctcctctt cataagtcta tcctatcaca aaaacgaaag aaaaacaatt acgaacgaaa
    40321 gtttaatttg ttgttttttg ctttttattt tggtagaata aaacggaggt gtaaaatgaa
    40381 aagattggaa caaattatta aattagtatc agaatatgaa aagatcgacg ttaatacatt
    40441 atcggaaaaa ttaaatgtat cgaaagtaac gattagaaaa gatttagata aattagaatc
    40501 aaaaggttta ttacacagag agcatggata tgctgtatta aatagtggag atgacttaaa
    40561 tgtacgtttg tcgattaact atgaaattaa gagaaaaatt gttcaggaag cagtaaaatt
    40621 ggtgtcagat aatgaaacaa taatgataga atctggatcg acctgtgctt tacttgctga
    40681 ggaaatttgc aagcaaaaaa gaaatgttac gattgtaaca aattcatttt ttatagcaaa
    40741 ttttgtgaga gcttatgatt catgtcgtat tattgttctt ggtggagagt ttcagaagga
    40801 ttcacaggtt actgtgggac ctttattaaa agaaatgata cagacttttc atgtgcgtca
    40861 agcttttgtt gggacagatg gctacgataa agagatgggc tttacaggaa aagatttaat
    40921 gcgcagtgag gtagttcaat atatttcagc agcgtcggat aaagtcattg tactaactga
    40981 ctcaagtaaa tttgataaaa ggggtacagt aagaagattt gctttaagtc aagtctatga
    41041 agtaataaca gacgaaaaac tttctaaaca aaatatagct acattagaaa atgctgggat
    41101 aatggttaag gtagtttcgt aagaggttaa gtgtatgaat caagatagga ataaactgct
    41161 ttctaaaatt gcttatctgt attatattga aaacttaaat cagtcacaaa tagcagcaaa
    41221 attaggaatt tatagaacct ctattagtag aatgttaaca gaagcaagga atgcaggaat
    41281 tgttaaaatt gaaatagaga attttgatac aaatatgttt aagttggaaa attatgtaaa
    41341 agaaaaatat ggtctggaaa gtttagaaat tattccaaat gaatttgatg ataatccaac
    41401 aattttatct gaaagaattt ctcaagttgc agcaggtgtc cttaggaatt taattgatga
    41461 taatatgaaa attggctttt cttgggggaa aagtttaagt aatttagtag atttaattca
    41521 cagtaaaagt gtccgaaatg ttcacttcta tcctctagca ggtggtccta gtcacataca
    41581 cgctaaatac catgtgaata cactgattta tgaaatgtct agaaaatttc atggagagtg
    41641 tacatttatg aatgcaacga ttgtgcaaga aaataaattg ttagcagatg gtattttgca
    41701 atcaagatat tttgaaaatt tgaaaaatag ttggaaagat ttagatatag ctgtagtcgg
    41761 aattggtgat tttagcaata aaggaaaaca tcaatggtta gacatgctta cagaggatga
    41821 ctttaaagaa ttgaccaaag ttaaaactgt aggagaaatt tgttgtcgat tttttgattc
    41881 aaaaggtaaa gaagtctatg aaaacttaca ggaaagaacg atagcaatct ctttggaaga
    41941 tttaaaaaat attcctcaaa gtttagctgt tgcttacggt gatacgaaag tatcttcgat
    42001 tctttctgtc ttgcgtgcta atttagtaaa tcatttgatt acagataaaa atacaatttt
    42061 aaaagttttg gaagaagatg gggatttgac ttttagagag attctaggtg agtgaaaatg
    42121 atagactgat cagtttatcg ttttttcttt ttagtcgatt gcacatttgt gctcatataa
    42181 acaaaaatag tttatctgtt gtttttggat tgacaacttt attatgtagt tgtattctat
    42241 agttacaaaa gaaaatttta aaatttcaaa tgaaaaaagc tttttacata gtgaaatgag
    42301 gaggaattta tggaaattat tgttccagat caaattatca tgggtttaat tttatatgct
    42361 ggtgatgcga aacaacatat ttataaagcg ttagattaca taaaaaatgg tacatgtgaa
    42421 cggtgtgaag aagaaatcca gttagctgat gccgccttat tagaagctca taatctacaa
    42481 acaaaatttt tggcacagga agcgtctggt acaaagacag aaattacagc tctctttgtt
    42541 cattcacaag atcatctcat gactagtatg acggagatta atttaatcaa agaaattatt
    42601 agtttgagaa aagaacttca taaaaaataa tactagagta ttatcattgt tattaacata
    42661 gaggaggaaa acataatggt gaagattggt ttgttttgtg cagcaggttt ttctactggt
    42721 atgcttgtaa ataatatgaa aattgcagcg caagctagtg gagttgaggc agaaatagag
    42781 gcgttttctc agtctaaatt agcggattat gcgccaaata tagatgttgc actattgggt
    42841 ccacaagttg cttatacatt agataaatca aaagaaattt gtgataagtg tgatgttccg
    42901 atagctgtta ttccgatgat ggactatggt atgttagatg ggaaaaaagt attagatttg
    42961 gccctatctt tgattagtgg gtaagaaaag gagatttatt atgtcaaaga tggatgttca
    43021 gaaaatcatt gcaccgatga tgaagtttgt gaatatgcgt ggcactatag ctctaaaaga
    43081 tgggatgtta gcaattttgc cattgacagt agttggtagt ttgttcttga ttatgggaca
    43141 attgccgttc gaaggattaa ataagagcat tgctagtgtt tttggagcta attggacaga
    43201 gccgtttatg caagtatatt caggaacttt tgctattatg ggtctaattt cttgtttttc
    43261 aattgcctat tcttatgcta agaatagcgg agtagaggct ttaccagctg gagttctatc
    43321 tgtatctgca ttctttattt tgctaagatc atcttatatc cctaaacaag gtgaggcgat
    43381 tggggacgct attagtaaag tttggtttgg aggccaagga attatcggtg ctatcattat
    43441 aggtttggta gtaggaagta tttatacctt ctttataaag agaaaaattg ttattaagat
    43501 gccagaacaa gttccacaag ctattgccaa acagtttgaa gcaatgattc cagcatttgt
    43561 aattttctta tcttctatga ttgtatatat tttagcgaag tcattgacta atggcggaac
    43621 attcatagaa atgatttatt ctgctattca agttccgttg caaggtttaa ctggatcttt
    43681 gtatggtgct attggaattg cattctttat atcatttttg tggtggtttg gtgttcatgg
    43741 gcaatcggta gtaaatggag tagtgacagc tctgctttta tctaatcttg acgctaataa
    43801 agctatgtta gcctctgcta atctatcatt agaaaatggt gcacatattg ttactcaaca
    43861 atttttagat tcatttttaa ttctatcagg ttcagggatt acgtttggtc ttgtagttgc
    43921 catgcttttt gcagcaaaat caaaacaata ccaagcctta ggaaaagttg cagcttttcc
    43981 agcaatattt aacgtaaatg agccagttgt atttggattt ccgattgtca tgaatccagt
    44041 tatgtttgta cctttcattc ttgttcctgt acttgcagct gtgatagtat atggagctat
    44101 tgcaacaggt ttcatgcagc cattctcagg ggtaacattg ccttggagta caccagctat
    44161 tctatcagga tttttggtgg gtggatggca aggtgttgtg actcagttat tagtattggt
    44221 gatatctaca gtggtttact ttccattctt taagatacaa gatcgtttag cttaccaaaa
    44281 tgaaatcaaa caatcttaga ggtatttgtg tgttactgtt aaactcacac atttgtgcta
    44341 aaaattagag agttaaaatt tttctagtta aaagcttgaa aatttctata aaaatcggta
    44401 ttatattttc gaaagaaata aaaatatttt cgaaagaaag gtgcttacga tggtaaatac
    44461 agaagtagca agaacaacaa tcaagacaga atattttggc agccttactg aaaggatgaa
    44521 caaatatcga gaagatgttt taaataaaaa accttatatt gatgctgaga gagcagttct
    44581 agcaacacgc gcctatgaac gatacaagga acaacctaat gtcctaaaac gtgcatatat
    44641 gctgaaagaa attttggaaa atatgtctat ctatattgaa gaagaatcta tgattgcggg
    44701 aaatcaagct tcttccaata aagatgctcc tatttttccg gaatatacgc tagaatttgt
    44761 tctcaatgag ttggatcttt ttgaaaagcg tgatggagat gttttctata ttacagaaga
    44821 aacaaaagaa caacttagaa gtattgctcc gttttgggaa aataataatt tacgtgctag
    44881 agctggtgcc ttattacctg aagaagtgtc agtttatatg gaaacaggat tcttcggtat
    44941 ggaaggtaag atgaattctg gagatgctca cttagcagtt aactatcaga aacttttgca
    45001 atttggttta agaggttttg aagagcgggc tcgtaaagca aaagtagctc tagatttaac
    45061 agatccagca agtattgata aatatcattt ttacgactct atatttatcg taatcgatgc
    45121 tattaaagta tatgcaaagc gctttgttgc tcttgctaaa agtttagccg aaaatgcaaa
    45181 tcctaaacgt aagaaagaat tacttgagat tgcagatatt tgctctagag tcccatatga
    45241 accggcaact acttttgcag aagctattca atcagtttgg tttattcaat gtattttaca
    45301 aattgaatct aatggccact ctctttcata tggccgtttt gatcaatata tgtatccata
    45361 tatgaaggct gatttagaaa gtggtaaaga aacagaagat agcattgttg aacgtctgac
    45421 aaatctttgg attaagacaa ttacaattaa taaggttcgc agtcaatcac atacattttc
    45481 ttcagcagga agtcctttat atcaaaatgt tacaattggt ggacagactc gagataagaa
    45541 ggatgctgtt aacccattat cttatttggt attaaaatca gttgcacaaa cccatctacc
    45601 gcaacctaat ctaactgtac gttaccatgc aggtttagat gctcgtttca tgaatgagtg
    45661 tattgaagtg atgaaacttg gttttggtat gcctgcattt aataatgatg agattattat
    45721 tccttctttt attgcaaaag gagtattgga agatgatgct tatgattaca gtgccattgg
    45781 atgtgttgaa acggcagttc cagggaaatg gggctatcgt tgcacaggta tgagttatat
    45841 gaacttccct aaggttctac ttatcacgat gaatgatgga attgatccgg cttcgggtaa
    45901 acggtttgca ccaagctttg gtcattttaa ggatatgaag aacttttctg aattagaaaa
    45961 tgcttgggat aaaacactaa gatatttgac acgaatgagt gttattgttg aaaattctat
    46021 tgatttatca ttggaacgag aagttcctga tattctatgt tcagcattga ctgatgattg
    46081 tattggtcgt ggaaaacacc ttaaagaagg tggagcagta tatgattata tatcaggatt
    46141 gcaagttgga attgcaaatt tgtcggattc attagctgca attaaaaaat tggtgtttga
    46201 ggaagaacgt ataagcccaa gtcagctttg gcatgcactg gaaacagatt atgccggaga
    46261 agaaggtaag gtcattcaag aaatgttgat tcatgatgca cctaagtatg gtaatgatga
    46321 tgattatgct gacaaattgg ttactgctgc ttatgacatt tatgttgatg aaattgctaa
    46381 atatcctaat acacgttatg gaagaggtcc aattggagga attcgttatt caggaacatc
    46441 ttctatctca gccaacgtag ggcagggacg tggaacatta gcaactccag atggacgcaa
    46501 cgcgggtaca ccgttagcag agggttgttc accatcacat aatatggatc aacacggccc
    46561 tacatctgtt ttaaaatctg tttcaaaatt accaacagat gaaatcgtag gtggggttct
    46621 cttaaatcag aaagtaaatc ctcaaacgtt agccaaagaa gaagataaat taaaactaat
    46681 tgctttgtta cgaacattct ttaatcgttt acatgggtac catattcaat acaatgttgt
    46741 ttccagagag acgctgattg acgctcagaa acatcctgaa aaacacagag acttaattgt
    46801 tcgtgttgca ggatactctg cattcttcaa tgttctttct aaggcaaccc aagatgacat
    46861 tataggacgt actgagcata ctttgtaaaa taaagaggtt ctttttatgg aatttatgct
    46921 tgacacatta aatttagatg agattaaaaa gtggtctgaa attttgccgc tagctggggt
    46981 aacttcaaat cccactattg caaaaagaga gggttctatt aatttttttg aacgaatcaa
    47041 agatgtaaga gaattgattg gctctacacc ctctattcat gttcaggtga tttctcaaga
    47101 ttttgaaggc atcttaaagg atgctcatga aattcgaaga caagcaggag atgatatatt
    47161 tatcaaagta cctgttactc cagctggatt acgtgcaata aaggtgctaa aaaaagaggg
    47221 ctaccatatc actgcaacag ctatttatac agttattcag ggattattag ctatcgaagc
    47281 aggagctgat tacctagctc catattataa tagaatggaa aatctgaaca ttgattcaaa
    47341 ttctgtcatt cgtcaattag ctcttgctat tgatagacag aactctccta gtaagatttt
    47401 agctgcatcc tttaaaaatg tagcacaagt aaataatgct ttagctgcag gtgcgcatgc
    47461 tgttacagca ggagcagatg tttttgaatc agctttcgcc atgccatcta tccaaaaggc
    47521 ggttgatgat ttttctgacg attggtttgt tactcaaaat agtcgttcca tttagataga
    47581 gaggaaatat atatgagaat ttttgctagt ccttctagat atattcaggg ggaaaatgcc
    47641 ttgtttgaaa atgccaaatc aattttggat ttgggaaatt accctattct attatgcgat
    47701 cagttggttt atgatattgt tggaaaacga tttgaagatt acctacatag gtatggtttc
    47761 catattgttc tggcgctatt taatggtgaa gcttctgaca atgaaatcaa tcgagttgtt
    47821 gccttggctg agaaagaaaa ttgtgatagt attatcggtc ttggtggggg aaagacgatt
    47881 gatagcgcaa aagctattgc agatttgatt gaaaagcctg ttattattgc tccaacaatt
    47941 gcatcgaccg acgcacctgt atctgcttta tctgttattt atacagatga aggtgcattt
    48001 gatcattatc tattttattc taaaaatcca gatttagttt tggttgatac aaaagttatt
    48061 tcacaagccc ctaagcgttt attagcgtct ggtattgcag atggtttagc aacttgggtt
    48121 gaggcgcgtg cggttatgca ggcaaatgga aaaactatgt tgggacaaca gcaaacattg
    48181 gctggagttg caattgcgaa gaaatgtgaa gaaacgctgt ttgcagatgg tttacaggct
    48241 atggcagctt gtgaagctaa agtggtgaca ccagcattag aaaatattgt tgaagctaat
    48301 actttattga gtggtctagg ttttgaaagt ggaggattag ctgcggcgca tgcaattcat
    48361 aatggtttta ctgcattgac aggtgacatt catcatttaa cacatggtga aaaagtagct
    48421 tatggaactt tagtacaact attattggaa aatagaccta aagaagaact tgataagtat
    48481 attgagtttt acaaaaaaat tggtatgcca acaactctaa aagaaatgca tttggatcaa
    48541 gttggatatg atgatttaat aaaagttggt aaacaagcaa ctatggaggg tgagacaatt
    48601 catcagatgc cgtttaagat ttcgccttca gatgttgctc aagctattat cgctgtagat
    48661 gcctatgtaa attcaaaata aacaataagg actactgttt tccaaatggt agtcttttat
    48721 tgatccctgt attgaattct atagaagatt gaaataggat gagaacaaat cgattgggaa
    48781 agtaaaatta atttctataa atgttttagc aattgtttcg tactatttca gattcagtct
    48841 actatacgtt cttcataaat caaaaagcga cataggttgt cggctattta ttgtgaatac
    48901 attaattagc attccagttt tatcttcggt ctaaagtaag tattttgtgc tatacgagat
    48961 aagcttcttg acttactcct tgatttactg cataacaatg ggataaaaag tgggagatag
    49021 agcaattcat agtcatcaaa attaatgaga tacagtatac agttttttct ttaaacacat
    49081 ttcaaattcc ctcaaaaatg gtataatagt aacatcacaa aattggagag agaccatgag
    49141 tttttataat cataaagaaa ttgagcctaa gtggcagggc tactgggcag aacatcatac
    49201 atttaagaca ggaacagatg catcaaaacc taagttttat gcgcttgata tgttccctta
    49261 tccgtctgga gctggtctgc atgtaggaca cccagaaggt tatactgcaa ccgatatcct
    49321 cagtcgttac aaacgtgcgc aaggctacaa tgtccttcac ccaatgggtt gggatgcttt
    49381 tggtttacct gcagagcaat acgctatgga tactggtaat gacccagcag aatttacagc
    49441 ggaaaacatt gccaacttca aacgtcaaat caatgcgctt ggattttctt atgactggga
    49501 tcgtgaagtc aacacaacag atccaaacta ctacaagtgg actcaatgga ttttcaccaa
    49561 gctttacgaa aaaggcttgg cctatgaagc tgaagtgcca gtaaactggg ttgaggaatt
    49621 gggaactgcc attgccaatg aagaagtgct tcctgacgga acttctgagc gtggaggcta
    49681 tccagttgtc cgcaaaccaa tgcgccaatg gatgctcaaa atcacggctt acgcagagcg
    49741 cttgctcaat gacttagatg aattagattg gtcagagtct atcaaggata tgcaacgcaa
    49801 ctggattggt aaatcaactg gtgccaatgt aactttcaaa gtaaaaggaa cagacaagga
    49861 atttacagtc tttactactc gtccggacac acttttcggt gcgactttca ctgtcttggc
    49921 tcctgaacat gaattagtag acgctatcac aagttcagag caagcagaag ctgtagcaga
    49981 ctataaacac caagccagcc ttaagtctga cttggctcgt acagaccttg ctaaggaaaa
    50041 aactggtgtt tggacaggtg cctatgccat caaccctgtc aatggtaagg aaatgccaat
    50101 ctggattgcg gactatgttc ttgctagtta tggaacaggt gcggttatgg ctgtgcctgc
    50161 ccacgaccaa cgtgactggg aatttgccaa acaatttgac cttccaatcg tcgaagtact
    50221 tgaaggtgga gatgtcaaag aagctgccta cacagaggat ggcctgcatg tcaattcaga
    50281 cttcctagat gaactcaaca aagaagacgc tattgccaag attgtggctt ggttggaaga
    50341 aaaaggctgt ggtcaggaga aggttaccta ccgtctccgc gactggctct ttagccgtca
    50401 acgttactgg ggtgagccaa ttccaatcat tcattgggaa gatggaactt caacagctgt
    50461 tcctgaaact gaattgccgc ttgtcttgcc tgtaaccaag gatatccgtc cttcaggtac
    50521 cggtgaaagt ccactagcta acttgacaga ttggcttgaa gtgactcgtg aagatggtgt
    50581 caaaggtcgt cgtgaaacta acaccatgcc acaatgggca ggttcaagct ggtactacct
    50641 ccgctatatt gatccacaca atactgagaa attggctgat gaggacctcc tcaaacaatg
    50701 gttgccagta gatatctacg tgggtggtgc agagcatgct gttcttcact tgctttacgc
    50761 tcgtttctgg cacaaattcc tctatgacct cggtgttgtt ccgactaagg aaccattcca
    50821 aaaactcttt aaccaaggga tgattttggg aacaagctac cgtgaccacc gtggtgctct
    50881 tgtggcaacc gacaaggttg aaaaacgtga tggttccttc ttccatgtag aaacagggga
    50941 agagttggag caagcgccag ccaagatgtc taaatcgctc aagaacgttg ttaacccaga
    51001 cgatgtggtg gaacaatacg gtgccgatac ccttcgtgtt tatgaaatgt ttatgggacc
    51061 actcgatgct tcgattgctt ggtcagaaga aggtttggaa ggaagccgta agttccttga
    51121 ccgagtttac cgtttgatta caagtaaaga aatccttgcg gaaaacaatg gtgctcttga
    51181 caaggtttac aacgaaacag tcaaagctgt tactgagcaa attgagtctc tcaaattcaa
    51241 cacagctatt gcccaactta tggtctttgt caatgctgct aacaaggaag ataagcttta
    51301 tgttgactat gccaaaggct ttattcaatt gattgcacca tttgcacctc acttggcaga
    51361 agaactctgg caaacagtcg cagaaacagg tgagtcaatc tcttatgtag cttggccaac
    51421 ttgggatgaa agcaaattgg ttgaagatga aattgaaatt gtcgtccaaa tcaaaggaaa
    51481 agtccgtgcc aaactcatgg ttgctaaaga tctatcacgt gaagaattac aagaaatcgc
    51541 tttagctgat gaaaaagtca aagcagaaat tgacggtaag gaaatcgtga aagtaattgc
    51601 ggtaccgaat aaactcgtta atatcgtcgt taaataacga gtttattagc tctatctgcc
    51661 accttcaata gtccactgga ctattgaagc caactaaatt agttaacatt gttgtgaaat
    51721 aagataggaa tccttcagag tagaatctgg aggatttttt gaatcttctt atgaaagtag
    51781 gatatatagt agactgaatc taaaatagta cgaaacaatt gctaaaacat ttatagaaat
    51841 taattttact ttcccaatcg atttgttctc atcttatttc aatacgctat actatgggca
    51901 actataaagt ttgaaaagcg aaacaaggag aaagttatac cagtaaacga atatggtcag
    51961 atgattggtg agtcaatgga aggttataca ccaggtgagc tgacttctat tgatctctta
    52021 gaagggcgtt atgctaggat agaggctctt tcagtggaaa agcatgcgga ggatttgcta
    52081 gctgtttatg gtcctgatac tcttcaggag atgtggacct acttctttca ggagccagta
    52141 gcagacatgg aggaactggt cagcctttta tagcaaaatg aaataagaac aggacaaatc
    52201 gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gtataagtgt actatttcag
    52261 tttcaatcta ctataaatca gatgttggct cgtaaggacc gtttttacta tgcaatcata
    52321 gacaaggcaa ctggtaaggc tttgggaact ttttctctca tgcgtattgg ccagtaacgg
    52381 agtaatagaa gtgggagctg ttactttttc tccaaaactc agggggacac ggatagggac
    52441 agaagcccaa tatctactgg ctcgctatgt ctttgaagag cttaactatc gttgttatga
    52501 gtggaaatgc gatgctctta acctgccatc cagacgtgct gcggagcgtt tgggctttat
    52561 ttatgaagga accttccgtc aggcagtggt ttataagggg cgtacgagag atacggattg
    52621 gttgtctatg attgataagg actggcccaa agtcaaagat cgtttggaaa catggttgcg
    52681 tcctgaaaat tttgataaaa atggacagca gtacaagagc ttgagagagt tttaagaggt
    52741 gttgacatga tcactattag aaagcaagaa atcgtcaagt tcgaggatgt tttgcatctc
    52801 tatcaggctg tcggttggac aaattataca aatcaacctc agatgctgga gcaggccttg
    52861 tatcattcat tagtaattta tctggcactt gatggtgatg ctgttgtggg cttgattcgt
    52921 ttggctggag atggtttttc atcagttttt gtacaggatt tgattgtttt gtctagctat
    52981 cagcgccaag ggattggtag ctccttgatg aaacaggctt taggaaattt taaagaggcc
    53041 tatcaagtcc agctggcgac agaacagaca gaaaaaacgt gggatttaat cgttctatgg
    53101 gctttgaaat cttatccacc tataattgga tagggatgac ttggatgaat cgtaaaaaat
    53161 aacaaaactt gttttttctt aagcaaaatt taaggatggt ctagtattat ataatcatta
    53221 aataaagacc tcctaacttt atttaataaa atcctaaact tttctttttc ataataatct
    53281 cccttaactc cacccaatca ggtggagttt tttagctcta tttcaggctt ttggggacta
    53341 ttctaaaaat aatttttcga tatttttcgg tatttttcgg attttggtcg gggaattggc
    53401 ggggactttt ttagcgaata tgactaagaa ataggtctgt ggtcgcttca gctagttcaa
    53461 actcaatttg attgtaagtg actgttaatt gaaggactgg aactactgta ataatgattt
    53521 tgcttgtcta gtagtggcgt attaaatgag aagtgacatg taagattgtc tcttcgttta
    53581 cgaaatcaaa atttctatga aattgataga atccctaacg ttctcttaat cttaaccgtc
    53641 ttgtcgtaca gcggttgaag aaaatgtaaa cctttgacaa aattcgtgaa ctatgggata
    53701 ataaaaagga attgagtact agttctatat cataggctag aaaagacccc aagctcacga
    53761 ccaaataagc ttgaggtctt ttttgacact atttgtcctt gtttagccat ttatcgacta
    53821 tacgaagaac gacaccgacc acaattggtc cgatgatagt tttgagtact aattctatca
    53881 tgggctatct cacctccttt cgtaggcggt gtagaagtgc cgtataatat tataccacat
    53941 aagtgctaaa cttaggagtc acccaatcag gtggcttttt tgtttgtggc ttgttttttt
    54001 gatataatag agccatgagt agaattttag ataatgagat gatgggtgat gaggagttag
    54061 tagaacgcac gctccgtcct cagtatttac gtgaatatat tggtcaggat aaggttaagg
    54121 atcagcttca gatctttatc gaagccgcta aaatgcggga tgaagcgctg gatcatgtgc
    54181 tcttatttgg ccctccaggg cttgggaaaa caaccatggc ttttgtcatt gccaatgaac
    54241 tgggagtcaa tctcaagcaa acgtctggtc ctgttatcga aaaagcgggt gatttggtag
    54301 cgattttgaa tgagttagag cctggagatg tcctctttat tgacgagatt catcgcttac
    54361 ccatgtcagt ggaagaagtg ctttatagtg ccatggagga cttctacatc gatattatga
    54421 ttggggctgg tgaaggcagt cgcagtgttc atttggagtt gcctcctttt accttgattg
    54481 gtgcgacgac tcgggctggt atgctctcaa atccactacg ggcacgtttt gggattacag
    54541 gtcatatgga gtattatgcc catgctgact tgacagaaat tgtcgagcgg acggcagata
    54601 tttttgagat ggaaatcact catgaggcag catctgagtt ggccctacgt agtcgtggaa
    54661 cccctcgtat tgccaatcgt ctcctcaagc gcgtgcgcga ttttgcccag ataatgggga
    54721 atggggtaat cgatgatatt attaccgata aggctttgac tatgctggat gttgaccatg
    54781 aaggtttgga ctatgtggat caaaaaatcc ttcgtaccat gattgagatg tacagtggag
    54841 gacctgttgg tctaggaact ctttctgtca atatcgccga agagcgtgag acagttgaag
    54901 acatgtatga gccttacttg attcaaaaag gttttatcat gcggacacgg tctggacggg
    54961 tggcgactgc taaggcatat gagcacttag gttatgaata cagtgaaaaa taagcaagaa
    55021 atcttagagg cttttagaga aaatccagat atgatggcca ttctgacgat catccgagac
    55081 cttggtttga aagactcgta gttggcagca ggttctgtca gaaatttcat ctggaatctt
    55141 ttgtcagaca aatccccttt tgatcatgaa acagatatag atgtgatttt ctttgatcca
    55201 gatttttctt atgaggaaac cttattactg gagaaaaagc tgagagagga ttttcctcag
    55261 taccagtggg aattgaaaaa tcaggtctat atgcatcagc acagtcctca cactgcttcc
    55321 tataccagtt ctcgtgatgc tatgagtaag tatccagaac ggtgtacggc agttggactg
    55381 cgcttgaatg aagaatcaga ttttgaactc tatgcacctt atggtttgga ggatattttg
    55441 aattttcaag ttcgtccaac tcctcatttc ttagaaaatg aagaccgaat ggaactctat
    55501 caaacacgtt tatccaagaa aaattggcag gagaaatgga aaaatttgat ttttaaaaat
    55561 acttaaggaa actttaagct agggagtgta cactaagttc ataagttaag aagaccttaa
    55621 cttaaactcc taaaactttt tcataataat ctccctataa aaataaagtc gcccaatcag
    55681 gcggcttatt tttttgaaaa atgggcatgg tgcctgagaa taaatagctt agtgatagaa
    55741 gaaaatgggg aaatatggta taatgaaacg atagattttt gaataggaat aagatcatgt
    55801 ttggattttt taagaaagat aaggctgtgg aagtagaggt tccgacacag gttcctgctc
    55861 atatcggcat catcatggat ggcaatggcc gttgggctaa aaaacgtatg caaccgcgag
    55921 tttttggaca taaggcgggc atggaagcat tgcaaaccgt gaccaaggca gccaacaaac
    55981 tgggcgtcaa ggttattacg gtctatgctt tttctacgga aaactggacc cgtccagatc
    56041 aggaagtcaa gtttatcatg aacttgccag tagagtttta tgataattat gtcccggaac
    56101 tacatgcgaa taatgttaag attcaaatga ttggggagac agaccgcctg cctaagcaaa
    56161 cctttgaagc tttaaccaag gctgaggaat tgactaagaa caacacagga ttgattctta
    56221 attttgctct taactatggt ggacgtgctg agattacaca ggcgcttaag ttgatttccc
    56281 aggatgtttt agatgccaaa atcaacccag gtgacatcac agaggaattg attggtaact
    56341 atctctttac tcagcatttg cctaaggact tacgagaccc agacttgatt atccgtacta
    56401 gtggagaatt acgtttgagc aattttcttc catggcaggg agcctatagt gagctttatt
    56461 ttacggacac cttatggcct gattttgacg aagcggcctt gcaggaagct attcttgcct
    56521 ataatcgtcg tcatcgccga tttggaggag tttaggagga aatatgaccc aggatttaca
    56581 gaaaagaacc ttgtttgcag ggattgccct ggctattttc ctaccaattt taatgattgg
    56641 gggcctcttg cttcagatag caatcggaat catagccatg ctagccatgc atgaactttt
    56701 gaagatgaga ggtctagaga ccatgacgat ggagggcctc ttgaccctct ttgcaacctt
    56761 tgcattgacc attcccttgg agaattacct gacttttttg ccagttgatg ggaatgtggt
    56821 tgcctatagt gttttgattt caatcatgtt aggaacgacc gtttttagca agtcttatac
    56881 gattgaggat gcggttttcc ctcttgctat gagcttctac gtgggctttg gatttaatgc
    56941 tttactagat gctcgtgttg caggtttgga caaggctctc ttagccttgt gtatcgtctg
    57001 ggcgacagac agtggtgcct atcttgttgg gatgaactat gggaaacgaa agttagcacc
    57061 aagggtatcg cctaataaaa cccttgaggg tgccttgggt ggtattttag gagcaatttt
    57121 agtaaccatt atctttatga tagttgacag tacagttgct cttccatatg gaatttacaa
    57181 gatgtcagtc tttgctattt tctttagcat tgctggacaa tttggtgatt tactagaaag
    57241 ttcgatcaaa cgtcattttg gtgttaagga ttctgggaaa tttatccctg gacatggtgg
    57301 tgttttggat cgtttcgata gtatgttgct tgtatttcca atcatgcact tatttggact
    57361 cttttaatca aaagacggag gaaacgctat gctcggaatt ttaaccttta ttctggtttt
    57421 cgggattatt gtagtggtgc acgagttcgg gcacttctac tttgccaaga aatcagggat
    57481 tttagtacgt gaatttgcca tcggtatggg acctaaaatt tttgctcaca ttggcaagga
    57541 tggaacggcc tataccattc gaatcttgcc tctgggtggc tatgtccgca tggccggttg
    57601 gggtgatgat acaactgaaa tcaagacagg aacgcctgtt agtttgacac ttgctgatga
    57661 tggtaaggtt aaacgcatca atctctcagg taaaaaattg gatcaaacag ccctccctat
    57721 gcaggtgacc cagtttgatt ttgaagacaa gctctttatc aaaggattgg ttctggaaga
    57781 agaaaaaaca tttgcagtgg atcacgatgc aacggttgtg gaagcagatg gtactgaggt
    57841 tcggattgca cctttagatg ttcaatatca aaatgcgact atctggggca aactgattac
    57901 caattttgca ggtcctatga acaattttat cttaggtgtc gttgtttttt gggttttaat
    57961 ctttatgcag ggtggtgtca gagatgttga taccaatcag ttccatatca tgccccaagg
    58021 tgccttggcc aaggtaggag taccagaaac ggcacaaatt accaagattg gctcacatga
    58081 ggttagcaac tgggaaagct tgatccaagc tgtggaaaca gaaaccaaag ataagacggc
    58141 atcgactttg gatgtgacta tttctgaaaa ggggagtgac aaacaagtca ctgttacacc
    58201 cgaagatagt caaggtcgtt accttctagg tgttcaaccg ggggttaagt cagattttct
    58261 atccatgttt gtaggtggtt ttacaactgc tgctgactca gctctccgaa ttctctcagc
    58321 tctgaaaaat ctgattttcc aaccagattt gaacaagttg ggtggacctg ttgctatctt
    58381 taaggcaagt agtgatgctg ctaaaaatgg aattgaaaat atcttgtact tcttggcaat
    58441 gatttccatc aatattggga tttttaatct tattccgatt ccagccttgg atggtggtaa
    58501 gattgtgctc aatatcctag aagccatccg ccgcaaacca ttgaaacaag aaattgaaac
    58561 ctatgtcacc ttggccggag tggtcatcat ggttgtcttg atgattgctg tgacttggaa
    58621 tgacattatg cgactctttt ttagataatc gaggaatatt atgaaacaaa gtaaaatgcc
    58681 tatcccaacg cttcgcgaaa tgccaagcga tgctcaagtt atcagccatg ctcttatgtt
    58741 gcgtgctggt tatgttcgcc aagtttcagc aggtgtttat tcttatctac cacttgccaa
    58801 ccgtgtgatt gaaaaagcta aaaacatcat gcgccaagaa ttcgaaaaga ttggtgctgt
    58861 tgagatgttg gctcctgccc ttcttagtgc agaattgtgg cgtgaatcag gtcgttacga
    58921 aacctatggt gaagaccttt acaaactaaa aaaccgtgaa aaatcagact ttatcttagg
    58981 tccaactcat gaagaaacct ttacagctat tgtccgtgat tctgttaaat cttacaagca
    59041 attgccactc aacctttatc aaattcagcc caagtatcgt gatgaaaaac gcccacgtaa
    59101 tggacttctt cgtacacgtg agtttatcat gaaggatgct tatagtttcc acgctaacta
    59161 tgatagtttg gatagtgttt atgatgagta caaagcagcc tatgagcgta ttttcactcg
    59221 tagtggttta gacttcaagg ctattattgg tgacggtgga gccatgggtg gtaaggatag
    59281 ccaagaattt atggccatta catctgctcg tacagacctt gaccgctggg ttgtcttgga
    59341 caagtcagtt gcctcatttg acgaaattcc tgcagaagtg caagaagaaa tcaaggcaga
    59401 attgctcaaa tggatagtct ctggtgaaga taccattgct tactcaagtg agtctagcta
    59461 tgcagctaac ttagaaatgg caacaaacga gtacaaacca agcaaccgtg ttgtcgctga
    59521 agaagaagtt actcgtgttg caacgccaga tgttaaatca attgatgaag ttgcagcctt
    59581 cctcaatgtt ccagaagaac aaacgattaa aaccctcttc tacattgcag atggcgagct
    59641 tgttgcagcc cttctagttg gaaatgacca actcaacgaa gtcaagttga aaaatcactt
    59701 gggagcagat ttctttgacg ttgctagcga agaagaagtg gcgaatgttg ttcaagcagg
    59761 atttggttca cttggaccag ttggcttgcc agagaatatt aaaattattg cagatcgtaa
    59821 ggtgcaagat gttcgcaatg cagttgtcgg tgctaacgaa gatggctacc acttgactgg
    59881 tgtgaaccca ggccgtgatt ttactgcaga atatgtggat atccgtgaag ttcgtgaggg
    59941 tgaaatttcc ccagatggac aaggtgtcct taactttgcg cgtggtattg agatcggtca
    60001 tattttcaaa ctcggaactc gctattcagc aagcatggga gcagatgtct tggatgaaaa
    60061 tggtcgtgct gtgccaatca tcatgggatg ttacggtatc ggtgtcagcc gtcttctttc
    60121 agcagtgatg gagcaacacg ctcgcctctt tgttaacaaa acgccaaaag gtgaataccg
    60181 ttacgcttgg ggaatcaatt tccctaaaga attggcacca tttgatgtgc atttgattac
    60241 tgttaatgtc aaggatgaag aagcgcaagc cttgacagaa aaacttgaag caagcttgat
    60301 gggagctggt tatgaagtct tgacagatga ccgtaacgaa cgtgtcggtg ttaaatttag
    60361 cgatagtgac ttgattggtc ttccaatccg tatcactgtt ggtaaaaaag cggccgatgg
    60421 cattgtagaa gttaagatca aggcaactgg tgacaccatt gaggttcatg cagataacgt
    60481 gcttgaaacg cttgaaatcc taagcaagaa ataaaaacta taatcagaag aaaaacaagg
    60541 aaaaaatgta actagttttt accttgtttt ttctgtataa tgggagaaat gagtagataa
    60601 agaggtaaat gttatgctaa gatttccaaa ggattttgtc tggggatcct ctacttctgg
    60661 accgcagaca gaaggacgtg tagctggtga cggtaaggga gacaatctct gggattactg
    60721 gttccaagtg gagccaaatc gttactataa tgggattggt tcagataaga catcgacttt
    60781 ttatgaaaat tgggagcggg atattgagct tttgttagag actggtcaca cagtctttcg
    60841 gacttctatt cagtggtcac ggatttttcc acaaggctgt gggaaagtca accctcaagg
    60901 tgtggatttt tatcgtaagg tctttgaggc tattaaggct aaaggaattc gtctgttagt
    60961 caatctctat cattttgatt taccttttgc ccttcaagag gatggtgatg gttgggaaaa
    61021 taaggcgaca gtctcagcct atgaagacta tgctcgtttt tgttttgaga cttatggaga
    61081 tttagtggat caatggatta cctttaacga gcccatcgtt cctgtagaat ttggttattt
    61141 ttatgatgcc cattatccac ataaggtgga tgcagaggca gctgttaagg tagcctatca
    61201 tacacaattg gccagcagcc gggctgttaa ggcttgccat gaacttttgc ctgattccaa
    61261 gattgggatt gtcctcaact tgacaccggc ttatccacgt agccagcatc ctgctgatgt
    61321 caaggcagct cgtattgcgg ccctttttca ggcccaatct ttcttagatc catctgtctt
    61381 ggggacttat ccacaggagt tggtagaaat cttgcatgaa cacggtcttt tacctgatgc
    61441 tacagaggaa gagttggaac tcattcgtga taatacggtg gacttccttg gtgtgaacta
    61501 ctatcaacct ttgcgtgtta tggctcctcg atttgctaag catccagaga gtccactctt
    61561 accagaacat ttttacgagc cttatgtgat gcctggacgt aaaatcaatt ctcaccgtgg
    61621 ttgggagatt tatgagcaag ggatttatga catcgcccaa aatatcaagg aaaattatgg
    61681 caatattgaa tggatgttga ctgagaatgg tatgggtgtt gaaggggaag aaaaattccg
    61741 tcaagatgga atgattcaag atgattaccg tattgacttt gtaaaaggtc atcttcgtga
    61801 acttcaccgt gccattgaag atggtgccaa ctgtaagggc tacttgattt ggacctttat
    61861 tgactgctgg tcatggctca acagctataa aaatcgctat ggtttggtcg aattagactt
    61921 ggaaacgcaa gaacgtcgtc tgaagaaatc aggccactgg ttcaaagaat taagcgataa
    61981 taatggattt taaaaaggac tctgactgat tatcccaatc ggtcagagtt tttatgctta
    62041 caggagctta atttgaacta taccaatttt tactcttgac aagtgaaaga aacaagtata
    62101 tactgttttt gctgattcta taaaagatga attagactat accaatttta aggagaaagc
    62161 acagcttgcc tgtgtcgtat atactatgtg tggaattgtt ggtgttgttg gaaacacaaa
    62221 tgcaactgat attttgattc aagggcttga aaagcttgaa taccgtggct atgattctgc
    62281 gggaattttt gtcctagatg gtgctgataa ccatttggtg aaggcggttg gtcgtattgc
    62341 agaattgtct gccaagacag ctggtgttga gggaacaact ggtatcggac atactcgttg
    62401 ggctactcac ggaaaaccaa ctgaggacaa tgctcaccca caccgctctg agacggaacg
    62461 ttttgtcttg gtgcataatg gggtgattga gaactatctt gaaatcaagg aagaatacct
    62521 tgcaggtcac cacttcaagg ggcagacaga tactgaaata gccgttcatt tgattggaaa
    62581 atttgcggaa gaagaagggc tctcagttct tgaagccttc aaaaaagccc ttcacatcat
    62641 ccgtggttct tatgcctttg ccttggttga ctcacaagat cctgaagtca tctacgtagc
    62701 taaaaataaa tcaccacttt tgattggtct tggagaaggc tataacatgg tctgctcaga
    62761 cgccatggct atgattcgtg aaactaacca atacatggaa atccatgacc aagagttggt
    62821 aatcgtcaag gctgatagtg tggaagttca agactatgat ggaaatcgtc gtgagcgtgc
    62881 tagctacact gctgaacttg acttgtcaga tatcggtaag ggaacttacc cttactacat
    62941 gctcaaggaa attgacgagc aaccaactgt tatgcggaaa ctcatccaag cctacacaga
    63001 tgaggctggt caagttgtcg tagacccaga tatcattaag gctgttcaag acgcagaccg
    63061 catctacatc cttgcagctg gaacatctta ccatgcagga tttgcttcta agaaaatgtt
    63121 ggaagaattg acagatacac cagttgaact tggaatctca tctgagtggg gctacggtat
    63181 gccacttctc agcaagaaac cactcttcat ctttatcagc caatctggtg aaacagcgga
    63241 tagtcgtcaa gttttggtca aggctaatga aatgggaatt ccaagcttaa cagtgacaaa
    63301 cgttccaggt tcaaccctct cacgtgaagc caactatacc atgctccttc acgcaggtcc
    63361 tgaaattgcc gtggcatcaa ctaaagccta tacagcgcaa atcgcagccc ttgccttcct
    63421 tgcaaaagca gtcggagaag caaatggtaa tgctaaagcg caagcctttg acctggttca
    63481 tgaattgtca atcgtagctc agtctatcga atcaactctt tcagagaaag aaaccattga
    63541 agtcaaggtt cgtgaacttc ttgaaacaac tcgtaacgcc ttttacatcg gacgtggtca
    63601 agattactac gtagccatgg aagcaagtct caaactcaaa gagatttctt atatccagtg
    63661 tgaaggcttt gctgcaggag aactcaagca cggaaccatt gccttgattg aagaaggaac
    63721 gcctgttttg gctctcttgt cagatccagt tcttgccaat catactcgtg gaaatatcca
    63781 agaggtcgca gcccgtggtg ccaaagtcct cactatcgca gaagagaatg tagccaaaga
    63841 taccgacgat atcgtcctta cgaccgtaca tccatacctc tcaccaattt caatggtcgt
    63901 accaacgcaa ttagtcgctt actttgcaac cctccaccgt ggcctcgatg tggacaaacc
    63961 acgtaacctt gccaagtcag taacggtaga ataagctaaa aaagtctagt tatctaggct
    64021 ttttctaatg agcaaatcgg ttgcttgtac tcaagattcg tgttagaata atttttcaaa
    64081 ttgaagtaca gagatagata aggagaatca caatggtaga attgggaatt tcaacatttg
    64141 gggaaataac ggagcttgaa gggactggac aaacttacag tcatgctgaa cgcattcgcc
    64201 agttggtggc agagattgag ctggctgaca aggttggttt ggatgtatat gggattggtg
    64261 agcaccatcg ggcggatttt gcagtatcag ccccagagat tgttctggcc gctggggcag
    64321 tcaataccaa gaaaatccgt ttgaccagtg cagtcagcat tctgtcaagc atggacccga
    64381 ttcgtttgtt ccaacagtat gccactatcg atgctttgtc aaatggacga tcggagatta
    64441 tggctggaag gggctctttc acggaatctt tccctctgtt tggttatgac ttgaaagact
    64501 acgactctct ttttgatgag aaattagact tgcttcagtt agtcaatgaa aagaccaagt
    64561 tagactggca aggtcgattg actcaaacga ttgctggtaa agaagtttat cctcgtccag
    64621 ttcaggacaa attgcccttg tggatagcta caggtggtca tgtcgaatca acagtgaaga
    64681 ttgctcaggc tggtctaccg attgtatatg ctattattgg tggtaatcca cgttatttta
    64741 aaaagttgat tcaggcttat cgtgagattg gaagcgaagc gggccatgct gacaaagact
    64801 tgaaagtggg agcccattct tgggggtgga ttgcggaaga tggtgagcag gcggtgaaag
    64861 attatttcca tccgactaag caagtggtgg atgctatttc caaagaccgt ccgcactggc
    64921 aggaattgcg ttatgagcaa tatttggagc aggtagggcc aaatggcgcc atgtttgttg
    64981 gcaatccaga tcaggtggcc gaaaaattga ttcgcatgat agaggattta ggattggacc
    65041 gcttcatgct tcatctaccg cttggttcta tgcctcatga ccaggttctg agagctattg
    65101 aactcttcgg aacacaagtt gcacccaaag tacgagctta ttttgctatg aaagaggctt
    65161 aataaaaaat cctaatcaag tttattagga caacaaatat tgtacaaaaa ttaatccccc
    65221 gagctataat gcttggggga tttttctata ggagggctag tttagttctc ttttttattt
    65281 tttagtaaga aaccgagacc aaggagcgca aggaggctga ttcctgcaaa taggagtttg
    65341 ttttcgtttt tgattcctgt atttggaagt tcagcttgtt tatctggggt tgcaggtata
    65401 ttttccttgc tagagttttc taccgattcg tttcgaaccg cttcttttac agatgatgct
    65461 tgtgcttctt gtgctggttg ttcagcttgt gaatcagctg tagcttggct aggtttattt
    65521 tccgcatcag ctactttggc atctggttta gtagaatcag gtctagcttc tggagctggg
    65581 tcttgatgtg cagggtgaga agcttcattt tgatgttcag gcttggaagg ggttgagtct
    65641 ggtttctctt ctgcagttga ctcatggcta gttccatttt gagagactcg aagaacagta
    65701 gctgtaaggg cattcaattt caagcctttt tcagtccatt caagtccttt cgggttggca
    65761 attccgactg gtcctgcttg gttttcatct gccaaaactt ccgcatttct tagatgtgca
    65821 aaggcagttc ccaaattaaa ttcgcgagct ttttcatccg cattgacaaa gactgcgtag
    65881 atatcgccgt ttggagcagt gatttggtag ccaatcacta catcctcttt ttccacacca
    65941 ttttggcctg ggacagtgat gaggtggaca cggtctttga tatcttgaag actcttaagt
    66001 cggaaggcat ctgtagattg acgaagggca atcaaacctt tcatatagtc acggctcttg
    66061 acattttcag gataagcttt accatctgta gccttagtcc agtcaaactt gttgactgca
    66121 tcgctagaat cgtaagaatc atgaatgaag taaggatagt caaatgggtt gccgtcctta
    66181 tcacgcaaca agtgagattt gtttggaacc ttatcctctg ctacaggagt tctgtaggct
    66241 gggtcacgga attgtttggt acgtccatat tcctggccag agtggataaa cggagttcct
    66301 tgagctgtca agaccatgag atttccaagt ctcaaacgac ggtggatttc agcatagttc
    66361 tcagccttgc ttgggtcttt tttgatagac tgggcaatga tgtcaaagag ggtcaagtta
    66421 tcatgggctg cgatgtattg gatgacatct ccaggactgt ctgcttcaaa gttggttggt
    66481 tgagcaatga ggtttttgaa gatagtgttg atatcacgct tgccacctgt gataaaggca
    66541 ggttgacctt cgtttggata accagacttg aggttgttac ggatgtcatc tgagaagaca
    66601 gcaacagtat cggtatgttt catccaatct tggtcagcag ccttagtagg catattttca
    66661 tcaccagcat aggttctcca accttcaccc agcatgatga ggtttggatt gagggcgcgt
    66721 gcagccttgt aagcttcttc gatagaagcg gcatcatggt ctcccatcat atcgaaacgg
    66781 aagccatcca ctttgtaggt atcaactagg tatttgatag agtcaattag gagccgtttg
    66841 gtcatatggt gggttgtccc caagcgtcca ccaccaaagc tagttcgagg tgtgccatcg
    66901 gcatccataa agtggtagta gtttggttcc aaatcttcaa agagatcgac tttggctgtg
    66961 tggttataaa cgacatctag gatagctccc ataccacgtt tgtggatttc gttgatgagg
    67021 tttttaaatt ctgcgattcg tttttctgga ttcttaggat cgcttgagta cataccagtc
    67081 aaggagaagt agttttgagg gtcatatccc cagttgtagt tgctgttgct tgaagcgtag
    67141 tcagacaagc gttcatggtt tttcaattca ttgacaaagt agtaagacaa gactggaagg
    67201 agctggatat gggttacacc caagtctttg agatagtcta gtttttcaat gaaggcttca
    67261 aaagtcccaa atggtttggt caagtctttt gcaatggcag gatctgaagt gaaatcacgc
    67321 acatgagctt cgtagataac ggcgtcttca cgagtcttga aattgtgaat cttaccataa
    67381 gtcaagtctt gaggtccgag tttagctgga tctacaaagg cggctttagc cactttatgg
    67441 gcatcgtcaa tcttggcatc gtcgctattc caagcagcaa gagatttagc gtaaggatcg
    67501 agtgcaagaa cagttttacc ttgacgctcg atttggtatt gataatagta gccagtgaaa
    67561 tctgtgattc cgagtttgtt tgtgctgtct agagtttgtt tccaagttcc tctttcccct
    67621 ttttcaagag cgacagttcc aactactttg tcagggtcat tcttgtcgta gacaacaaca
    67681 gaaaccttat cagcacttgg tgaccaaagg gtcaaatcaa cttgttttcc ttcttctttt
    67741 aggtcagctc ccagtttgcc atcatagctg tatgtctcat ctttcaggcg ccagcttgtt
    67801 ttggtagtga attggtcgga attgtagcta acagtataag gatgttttgt gtcagagaaa
    67861 tctccgctgt aggtcacttt cttaccagct tcatcgattg caacatcggt aatagttacc
    67921 ttgtttccta ggtgattagt gatgttggag tgtttgagga tatcttcttt tttagcaccg
    67981 acaagtgttg aaaagctact ttcaatgcta gaagtgccta cgtgttgggc tcctgtcata
    68041 cggatatcat ggacatagta tggatttgtg taaatcgatt catcatcgtc ttttaggaaa
    68101 atttggctat gatttttcaa atctgtgaac ttataatttt ctttacggat tttcacgtcg
    68161 tctccttgtt tgctctcatc tagtaataaa aatccaaatt ctcttgcggc ttcattaaga
    68221 ggaatgtcga tatagcggcc atatttgcct gtagccgtaa agtctgttcc gtcaggccat
    68281 tgagcgctac ttggattttt cacatctccc cagtaccaga gagatttctt gtcatagttg
    68341 ccatctgtgc ggtagtagtt gacgcgaaca gttcctgcag gctgtggctc gtaagagaaa
    68401 accttgtaat cttggtctaa ccaagcctcg ttcatttttg gaactagttt ttctacagat
    68461 ttatcgccgg ttagattttt tccagctgta ttgttgatga ggaagctaat tttcttggct
    68521 tgttctccct ttaatttgac atctaggtaa tagccgtagt catctttctt ggcatccttg
    68581 aaggacaaag ctccgtttgg ccagttttca gatggttttt caacatcgtc ccaagtccat
    68641 agtccttgag catccttgtt ttcttcagga agttttttga catggatacg gaagtagtta
    68701 tcttcgatgg gctcttctgc cttagtttca gttgttactg gactagtaga agtagttggc
    68761 tctgttgcag gtttttcttc tgttttctct agggaagcgt ttgcatttct aggtgaagaa
    68821 atatcacttt cgttcttacc agagccagct gctgtatcag taagaggttg ggcaagggtg
    68881 gttgtatttc tgttgttggg ttcgttagtg gttggtgtac tttcgtcgga tgagatagtt
    68941 ggtgtagcca tggcaagcaa gacaaggctt gcgccgataa ggacagaacc agttccattt
    69001 ttgagggaac ggatgctgta gaccattttt ttctcagtgt gagatggtgt ttttctcata
    69061 atgattctcc aatcaataaa tttctatatc agtatagcat gtagtaaaac aatatgcaag
    69121 cgttttcttt gatttgtgaa aaaaattctt acttttgaga agttttctgt actattttat
    69181 atatcagtat aaatgacgga gataaaaatg tcacataagc caagccgtgt tattaggaag
    69241 atgatgtgtt ctcagctatt tttattcaga aattgatctc taacattacc aataaaaaag
    69301 aaaaatatct tgacaagcaa gggaaaattt tgttacaata atagacggta ctttttactt
    69361 ttggtctctc aagagtgtac agggacgtgc tgacaaatgt tgcaaaagta cacacagatg
    69421 atatctgtca ccaagtgtat catcaccaaa aataaaaaaa cacaggagaa tgtagatgcc
    69481 tacaattaac caattggttc gcaaaccgcg taaatcaaaa gtagaaaaat ctaaatcacc
    69541 agctttgaac gttggttaca atagtcataa aaaagttcaa acaaacgttt cttcaccaca
    69601 aaaacgtggt gttgcaactc gtgttggaac aatgacacct aaaaaaccta actcagccct
    69661 tcgtaaattc gctcgtgtac gtttgagcaa ccttatcgaa gttactgcct acatcccagg
    69721 tatcggacac aacttgcaag agcacagcgt ggtgcttctt cgcggtggac gtgtaaaaga
    69781 ccttccaggg gtacgttacc atatcgtccg tggtgcactt gatactgcag gtgttaacga
    69841 tcgtaaacaa ggccgttcta aatacggtac taaacgtcca aaagcataag gaaaggggat
    69901 aaagagaaat gagtcgtaaa aatagagctc caaaacgtga cgtattgcca gatccgctat
    69961 acaattcaca actagttact cgtcttatca accgcgttat gcttgatggt aaacgtggta
    70021 ctgctgcttc aatcgtttac ggtgcttttg agcaaatcaa agaagccact ggcaacgatg
    70081 cacttgaagt atttgaaaca gctatggaaa acatcatgcc tgtacttgaa gtacgtgcac
    70141 gtcgtgttgg tggttctaac taccaagtcc cagttgaagt tcgtccagaa cgtcgtacaa
    70201 cacttggact tcgttggttg gtaacaatcg ctcgtcttcg tggtgaacac acaatgcaag
    70261 accgtcttgc aaaagaaatc ttggatgctg ctaacaacac tggtgcagca gttaagaaac
    70321 gtgaagatac tcaccgtatg gctgaagcta accgtgcatt cgcacacttc cgttggtaag
    70381 ataggatgcg aaagcgttaa gaaagtccca gagaaaatag ggaatcgaag caggttgcgg
    70441 ttgcaaccaa tgagattcat ctttttctcc agacttttag cttgagctca actaaatcat
    70501 gatgctagga acggtaagga tgcaaggtga aaataggaaa ctgacgcagt attcgacgaa
    70561 tacaaggagt tttatctttt tcacgcggca tctcgttcca gctcacatcg gctaactaac
    70621 tttagcccgg gttcaaatta gctaaatcga ttagtattag ctataactca gcttaccatc
    70681 tcgtaagttg aaaccaacaa tagcatgaaa acattgagaa cgggtaggtc ctgcctatcc
    70741 gtttttatta aaatcgtgtt ataatagaat agaaatcaaa aataaatagg agaaacaaac
    70801 ctcatggcac gcgaattttc acttgaaaaa actcgtaata tcggtatcat ggctcacgtc
    70861 gatgccggta aaacaacaac tactgagcgt attctttact acactggtaa aatccacaaa
    70921 atcggtgaaa ctcacgaagg tgcgtcacaa atggactgga tggagcaaga gcaagaacgt
    70981 ggtatcacga tcacatctgc tgcgacaaca gctcaatgga acaaccaccg cgtaaacatc
    71041 atcgacacac caggacacgt ggacttcaca atcgaagtac aacgttctct tcgtgtattg
    71101 gatggtgcgg ttaccgttct tgactcacaa tcaggtgttg agcctcaaac tgaaacagtt
    71161 tggcgtcaag caactgagta cggagttcca cgtatcgtat ttgccaacaa aatggacaaa
    71221 atcggtgctg acttccttta ctctgtaagc acacttcacg atcgtcttca agcaaatgca
    71281 cacccaatcc aattgccaat cggttctgaa gatgacttcc gtggtatcat tgacttgatc
    71341 aagatgaaag ctgaaatcta tactaacgac cttggtacgg atatccttga agaagacatc
    71401 ccagctgaat accttgacca agctcaagaa taccgtgaaa aattgattga agcagttgct
    71461 gaaactgacg aagaattgat gatgaaatac ctcgaaggtg aagaaatcac taacgaagaa
    71521 ttgaaagctg gtatccgtaa agcgactatc aacgttgaat tcttcccagt attgtgtggt
    71581 tcagccttca aaaacaaagg tgttcaattg atgcttgatg cggttatcga ctaccttcca
    71641 agtccacttg acatcccagc aatcaaaggt attaacccag atacagacgc tgaagaaact
    71701 cgtccagcat ctgacgaaga gccatttgca gctcttgcct tcaagatcat gactgaccca
    71761 ttcgtaggtc gtttgacatt cttccgtgtt tactcaggtg ttcttcaatc aggttcatac
    71821 gtattgaata cttctaaagg taaacgtgaa cgtatcggac gtatccttca aatgcacgct
    71881 aacagccgtc aagaaatcga cactgtttac tcaggtgata tcgctgctgc cgttggtttg
    71941 aaagatacta caactggtga ctcattgaca gatgaaaaat ctaaaatcat ccttgagtca
    72001 atcaacgttc cagaaccagt tatccaattg atggttgagc caaaatctaa agctgaccaa
    72061 gacaagatgg gtatcgccct tcaaaaattg gctgaagaag atccaacatt ccgcgttgaa
    72121 acaaacgttg aaactggtga aacagttatc tcaggtatgg gtgaacttca ccttgacgtc
    72181 cttgttgatc gtatgcgtcg tgagttcaaa gttgaagcga acgtaggtgc tcctcaagta
    72241 tcttaccgtg aaacattccg cgcttctact caagcacgtg gattcttcaa acgtcagtct
    72301 ggtggtaaag gtcaattcgg tgatgtgtgg attgaattta ctccaaacga agaaggtaaa
    72361 ggattcgaat tcgaaaacgc aatcgtcggt ggtgtggttc ctcgtgaatt tatcccagcg
    72421 gttgaaaaag gtttggtaga atctatggct aacggtgttc ttgcaggtta cccaatggtt
    72481 gacgttaaag ctaagcttta tgatggttca tatcacgatg tcgactcatc tgaaactgcc
    72541 ttcaagattg cggcttcact ttcccttaaa gaagctgcta aatcagcaca accagctatc
    72601 cttgaaccaa tgatgcttgt aacaatcact gttccagaag aaaaccttgg tgatgttatg
    72661 ggtcacgtaa ctgctcgtcg tggacgtgta gatggtatgg aagcacacgg taacagccaa
    72721 atcgttcgtg cttacgttcc acttgctgaa atgttcggtt acgcaacagt tcttcgttct
    72781 gcatctcaag gacgtggtac attcatgatg gtatttgacc actacgaaga tgtacctaag
    72841 tcagtacaag aagaaattat taagaaaaat aaaggtgaag actaatccgt cctcactcta
    72901 gaaggaagtc acttagtggc ttccttttgt ctttagaaaa tacctctaaa tatggtaaaa
    72961 tagtagaaga ataatgtgag gaaaatgaat gtcaaatagt tttgaaattt tgatgaatca
    73021 attggggatg cctgctgaaa tgagacaggc tcctgcttta gcacaggcca atattgagcg
    73081 agttgtggtt cataaaatta gtaaggtatg ggagtttcat ttcgtatttt ctaatatttt
    73141 accgattgaa atctttttag aattaaagaa aggtttgagc gaagaatttt ctaagacagg
    73201 caataaagct gtttttgaaa ttaaggctcg gtctcaagaa ttttcaaatc agctcttgca
    73261 gtcctactat agggaggctt tctctgaagg tccatgtgct agtcaaggtt ttaagtccct
    73321 ttatcaaaat ttgcaagttc gtgctgaggg taatcagcta tttattgaag gatctgaagc
    73381 gattgataag gaacatttta agaagaatca tcttcctaat ttagccaaac aacttgaaaa
    73441 gtttggtttt ccaactttta actgtcaagt cgagaagaat gatgtcctga cccaagagca
    73501 ggaagaggcc tttcatgctg aaaatgagca gattgttcaa gctgccaatg aggaagcgct
    73561 ccgtgctatg gaacaactgg agcagatggc acctcctcca gcggaagaga aaccagtctt
    73621 tgattttcaa gcgaaaaaag ctgcagctaa acccaagctg gataaggcgg agattactcc
    73681 tatgatcgaa gtgacgacag aggaaaatcg tctggtattt gaaggggttg tttttgatgt
    73741 ggagcaaaaa gtgactagaa caggtcgtgt tttaatcaac tttaaaatga cggactatac
    73801 ttcaagtttt tctatgcaaa agtgggttaa aaacgaggaa gaggcccaga agtttgacct
    73861 catcaagaag aattcttggc tccgagttcg agggaatgtg gagatgaata acttcacacg
    73921 cgatttgact atgaacgtac aggatctgca ggaagttgtt cactatgagc ggaaggattt
    73981 gatgccagaa ggtgagcgtc gggttgagtt tcatgctcat actaacatgt cgactatgga
    74041 tgctttgcca gaggtcgaag agattgttgc aacagctgct aagtggggac acaaggcggt
    74101 tgctatcacg gaccatggga atgtccagtc ctttccacat ggctataagg cggctaagaa
    74161 agcgggaatc cagctgatct atggaatgga agccaatatc gtggaggacc gtgtccctat
    74221 cgtctataac gaagtggaga tggacttgtc agaagcaacc tacgtggtct ttgacgtgga
    74281 aacgacggga ctttcagcta tctataatga cttgattcag gttgcggcct ctaagatgta
    74341 caaggggaat gttattgctg aatttgatga atttatcaat cctgggcatc ccttgtcagc
    74401 ttttactaca gagttaactg gaattacaga tgatcatgtc aaaaatgcca aaccactaga
    74461 acaagttttg caagaattcc aagaattttg caaggatacg gtcctagttg cccacaatgc
    74521 tacctttgac gttggcttta tgaatgctaa ttatgagcgt catgatcttc caaagattag
    74581 tcagccagtt attgatacgc tggagtttgc tagaaacctc tatcctgagt ataaacgcca
    74641 tggtttgggg cctttgacca agcgttttgg tgtggccttg gaacatcacc acatggccaa
    74701 ctacgatgcg gaagcgactg gtcgtctgct tttcatcttt atcaaagagg tagcagaaaa
    74761 acatggtgtg accgatttag ctagactcaa cattgatcta atcagtccag attcttacaa
    74821 aaaagctcgg atcaagcatg cgaccatcta tgtcaagaat caggtaggtc taaaaaatat
    74881 ctttaagctg gtttccttgt ctaataccaa gtattttgaa ggagtgccac ggattccgag
    74941 aacggttcta gatgcccatc gagagggctt gattttaggt tcagcctgtt cagagggtga
    75001 agtttttgac gtggtcgttt ctcaaggtgt ggatgcggcg gttgaggtgg ccaagtatta
    75061 tgactttatc gaggtcatgc caccggctat ctatgcgccc ttgattgcta aagagcaggt
    75121 caaggatatg gaggaactcc agaccattat caagaatttg atagaggttg gagaccgcct
    75181 tggcaagcct gttttggcta cgggaaatgt tcactatatc gaaccggaag aagagattta
    75241 tcgtgaaatt atcgtccgta gtttgggaca gggtgcgatg attaaccgaa ctatcggtca
    75301 tggtgaacat gcccaaccag caccacttcc aaaggctcat tttcgaacga ctaatgagat
    75361 gttggatgaa tttgcctttt tggaagagga actggctcgt aaactggtta ttgaaaacac
    75421 caatgccttg gcagaaatat ttgaacccgt tgaagtcgtt aagggtgact tgtatacgcc
    75481 tttcatcgac aaggctgaag aaacagttgc tgagttgacc tataagaaag cttttgagat
    75541 ttatggaaat ccgctgccag atattgttga tttgcggatt gaaaaagaat taacatccat
    75601 actggggaat ggatttgctg tgatttatct ggcatcgcag atgctggtgc aacgttctaa
    75661 tgaacggggt tatttggttg gttctcgtgg gtctgtcgga tctagtttcg ttgcgaccat
    75721 gattgggatt acggaggtca atcctctctc tcctcactat gtctgtggtc agtgtcagta
    75781 cagtgagttt atcacagatg gttcgtacgg ttcaggattt gatatgcccc ataaggactg
    75841 tccaaactgt ggtcacaaac tcagtaaaaa cggacaggat attccgtttg agaccttcct
    75901 tggttttgat ggggataagg ttcctgatat tgacttgaac ttctcgggag aagatcagcc
    75961 tagcgcccac ttggatgtgc gtgatatctt tggtgaagaa tatgccttcc gtgcgggaac
    76021 agttggtacg gtagctgcca agactgccta tggatttgtc aaaggttacg agcgagatta
    76081 tggcaagttt tatcgtgatg cagaagtaga acgcctcgct caaggagcgg cgggtgtcaa
    76141 gcggacaaca ggccaacacc cggggggaat cgttgttatt ccgaactaca tggatgtcta
    76201 cgattttacg cctgtccagt atccagcaga tgatgtcacg gctgaatggc agaccactca
    76261 ctttaacttc cacgatatcg atgagaacgt cctcaaactc gatgtactgg gacatgatga
    76321 tccgactatg attcgaaaac ttcaggattt gtctggtatt gaccctaata aaattcctat
    76381 ggatgacgaa ggcgtgatgg cactcttttc tgggactgat gtgctagggg taacacctga
    76441 acaaattgga acgcctacgg gtatgttggg gattccagag tttggaacaa atttcgtacg
    76501 tggaatggta gacgaaaccc atccgacaac ctttgcggaa ttgcttcagc tgtctggtct
    76561 gtcccacggt actgatgttt ggttggggaa tgctcaggat ctgattaagc aaggaatagc
    76621 ggacctatcg actgttatcg gttgtcggga cgacatcatg gtttacctca tgcatgcggg
    76681 tctggaacct aagatggcct ttaccattat ggaacgggta cgtaagggtt tgtggctaaa
    76741 gatttcagaa gaggagagaa atggctatat cgaagcaatg aaggctaata aggtgccaga
    76801 gtggtatatc gaatcctgtg ggaaaattaa gtacatgttc cctaaggccc atgcggcagc
    76861 ctacgttatg atggccttgc gtgtagctta cttcaaggtt caccatccta tttattacta
    76921 ctgtgcttac ttctccattc gtgctaaggc ttttgatatc aagaccatgg gtgcgggctt
    76981 ggaggtcatc aagcgcagaa tggaagaaat ctctgaaaaa cggaagaaca atgaagcctc
    77041 taatgtggaa atcgatctct atacaactct tgagattgtc aatgagatgt gggaacgagg
    77101 tttcaagttt ggtaaattag atctctactg tagtcaggcg acagagttcc tcatcgacgg
    77161 ggataccctt atcccaccat ttgtagcaat ggatggtctg ggagagaacg ttgccaagca
    77221 actggtgcgg gcgcgtgaag agggagaatt cctctctaaa acagaactac gcaagcgtgg
    77281 tggactctca tcaaccttgg ttgaaaagat ggatgagatg ggtattcttg gaaatatgcc
    77341 agaggataac cagttgagtt tgtttgatga gttgttttaa aaaattgctt aataatctat
    77401 taaaagaggc taacgtatat ccaatagatt tacattagct ttcttttttg ttaaaatagt
    77461 ctatggaaag agggtgagag tatgtcaaag atgagtataa gcatccgtct ggatagtgag
    77521 gttaaggagc aggcccaaca ggtgtttagt aatctgggaa tggatatgac aacagctatt
    77581 aatattttcc ttcgtcaggc aattcaatat cagggattac cttttgatgt tagactagac
    77641 gaaaatcgga agttgctcca agcgttaacg gatttagacc aaaatcgtaa tatgagccag
    77701 tcttttgaat cagtctcaga tttgatggag gacttacgtg cttaagattc gttatcataa
    77761 acagtttaaa aaagatttta agttggctat gaagcgtggt ttgaaggcag aattattaga
    77821 agaagttttg aattttctgg ttcaagaaaa agaacatcct gccagaaatc gtgatcattc
    77881 attgacggca tccaagcatt ttcaaggagt tcgtgaatgc catacccagc cagattggct
    77941 tttggtttat aaagtagaca agtcggaatt gattttaaat ttgctgagga caggcagtca
    78001 cagtgattta ttttaatcta ttttaagggg gttctcatga aactaagaat atttgcggaa
    78061 gataagccgg ctaagaaggt atttgaatat caattagaac ttgctgatcg tacaattctt
    78121 ctatcgacag cactcttgtc aggtgctatt gctttagcag gaatcttttc tgctttgaaa
    78181 gaaaaataaa aatagaaaag agaaaacaga atggttttac caaattttaa agaaaatcta
    78241 gaaaaatatg cgaaattgtt ggttgcgaac ggaattaacg tgcaacctgg tcacactttg
    78301 gctctctcta ttgatgtgga gcaacgtgaa ttggcacatc taatcgtgaa agaagcttat
    78361 gccttgggtg cgcatgaggt catcgttcag tggacagatg atgtgattaa ccgtgagaaa
    78421 ttcctccatg ccccgatgga gcgtttggac aatgtgccag aatacaagat tgctgagatg
    78481 aactatctct tggagaataa ggctagccgt cttggagttc gttcatctga tccaggtgcc
    78541 ttgaacggag tggacgctga caagctttca gcttctgcta aagctatggg acttgccatg
    78601 aagcctatgc gtatcgcaac tcaatctaac aaggttagct ggactgtagc agctgcagca
    78661 ggacttgagt gggctaagaa agtcttccca aatgctgcga gcgacgaaga agcagttgat
    78721 ttcctttggg accaaatttt caaaacttgc cgtgtctacg aagcagatcc tgttaaggct
    78781 tgggaggaac atgcagccat tctcaagagc aaggccgata tgcttaataa ggagcaattt
    78841 tcagcccttc actacacagc gccaggaaca gatttaacac ttggtttgcc aaagaaccac
    78901 gtttgggaat cagctggtgc tgtcaatgca cagggcgaag aattcttgcc aaatatgcca
    78961 acagaagagg tcttcacagc gcctgacttc cgtcgtgcag atggttatgt cacttctaca
    79021 aaaccgctta gctacaacgg aaatatcatt gaaggcatta aggtgacctt taaggatgga
    79081 caaatcgtag atatcactgc tgagaagggt gatcaggtta tgaaagacct tgtctttgaa
    79141 aatgcgggtg cgcgtgcctt gggtgaatgt gccttggtac cagatccaag tccaatttct
    79201 cagtcaggca ttaccttctt taacaccctt ttcgatgaaa atgcgtcaaa ccacttggct
    79261 atcggtgcag cctatgcgac tagcgttgtt gatggagcgg agatgagcga agaggagctt
    79321 gaagctgcag ggcttaaccg ttcagatgtt cacgtagact ttatgattgg ttctaaccaa
    79381 atggatatcg atggtattcg tgaggatgga acgcgggtac ctcttttccg taatgggaat
    79441 tgggcaaatt aaggagataa tatgttagga agtatgttcg ttggtctcct agtgggattt
    79501 ttagcaggtg ctatgaccaa tcgtggagag cgaatgggat gttttggaaa aatgtttctc
    79561 ggttggatcg gagcctttct aggtcacttg ctctttggaa cttgggggcc agttttatca
    79621 ggaacagcta ttatcccagc gattttagga gccatgattg ttttagctat tttttggaga
    79681 cgaggaagtt aatttcctaa atctgatact caatgaaaat caaagagcaa actaggaaac
    79741 tagccgcagg atgctcaaag cactgctttg aggttgcaga tagaactgac gaagtcagct
    79801 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaacata tatacggcaa
    79861 ggcgacgttg acgcggtttg aagagatttt tgaagagtat gaaacgaaaa ggaggttggt
    79921 cattgtacta gcctcctttt gatatgatat aatagttcta tgagattaga taaattttta
    79981 gttgcctgtg cggtgggaag tcggactgag gtcaaaaact tgctcaaggc tgggcgcgtg
    80041 actgtaaatg gtaaaaaaga aaaatcagct aaattgcaga ttgatgaaaa aatagatgag
    80101 attcgctttg atgggcaagt gttggagtat gaagagtttg tctactacat gatgaacaag
    80161 cccaaaggag ttatctcagc gactgaggat cccaagcaca gaaccgttct ggacttgttg
    80221 gatgacttgg cgcggagtaa ggaagttttc ccagtaggac gcttggatat tgacacgcat
    80281 ggtcttttgc tcttgaccaa tgatggtcag ctggctcatg ttcttctttc gcccaagcgt
    80341 catgtggaca agacttatct ggcacaagtc aagggaatca tgacccaaga agatgtggag
    80401 acatttgctg agggtattcc tctcaaagac tttacctgtc aacccgctat actggagctt
    80461 gtatccatag atacagaaaa gaatcaaagc caaatccgtg tgaccattgc agaagggaag
    80521 tttcatcaga tcaagcgtat ggtgggctac tgtggcaagg aagtggtgga cttgcaacga
    80581 ttgactatgg gaactttagt attagatgag aacctagaac gaggggaatg gcgtcgcttg
    80641 accaaggaag aattagaaat tctccgcgct aatattattt aatttagttt aatactcaat
    80701 gaaaatcaaa gagcaaacta ggaaactagc cgcaggctgt acttgagtac ggcaaggcga
    80761 cgttgacgtg gtttgaattt gattttcgaa gagtataaat tcgaaaaagg tgagggacaa
    80821 tgtcctcgcc ttttatgttt tttagttgct tcctttgtga aaagagttat aatagactgt
    80881 agaataaaag gaggaatcta tgaacgcgat tcaagaatca tttactgata aactatttgc
    80941 caactatgaa gcaaatgtaa aataccaagc gattgaaaat gctgccagcc acaacggaat
    81001 ttttgcagct ctggaacgtc gccaaagcca tgtagacaac acacctgttt tctcattgga
    81061 tttaaccaag gacaaggtca ctaaccagaa agcgtctggt cgttgctgga tgtttgcggc
    81121 tctcaacacc ttccgccaca aactcatctc gcaatacaaa ttggagaact ttgagttgtc
    81181 acaagcccac actttcttct gggataagta tgagaaatca aactggttct tggagcaagt
    81241 cattgcgact tcagaccaag aattgactag ccgcaaggtt agcttcttac tccaaacacc
    81301 tcaacaagat ggcggtcaat gggatatggt cgtttccctc tttgaaaaat acggtgtcgt
    81361 gcctaagtca gtttatcctg agtctgtttc atctagcagc agtcgtgagc taaatgcgat
    81421 ccttaataaa ttgcttcgtc aagatgctca aatcttgcgt gacttgcttg tttctggtgc
    81481 agatcaagcg actgttcaag ctaagaaaga agacctcttg caagaaatct ttaactttct
    81541 tgctatgtca ttaggacttc caccacgcaa gtttgacttt gcttatcgcg ataaagataa
    81601 caactacaaa agtgaaaaag gaatcacacc acaagagttt tacaagaaat atgtcaatct
    81661 tcctttagaa gactacgttt ctgttatcaa tgctccaact gctgataaac cttacggaaa
    81721 atcttacaca gttgagatgt tggggaatgt ggttggtagc cgtgcagttc gctacatcaa
    81781 cgttccaatg gagcgcttga aagaattggc gattgcccaa atgcaagcag gtgagactgt
    81841 ttggtttggt tctgatgtcg gccagctcag caaccgtaag gctggcatcc ttgcgacaga
    81901 tgtttatgac tttgaatcaa gcatggacat taaacttact caagacaagg ctggacgttt
    81961 ggactatagt gaaagcttga tgacccacgc catggtcttg acaggtgttg acttggacga
    82021 aaatggtaaa tcaaccaagt ggaaggttga aaactcatgg ggagacaagg tcggtacaga
    82081 tggttacttt gttgcctcag acgcttggat ggacgaatac acataccaaa tcgttgttcg
    82141 taaggaattg ctgacagcag aagaacaagc tgcctatgga gcagaaccaa tcgtacttgc
    82201 accatgggat ccaatgggag ccttggctga ataaaagcat agaaaaaagg aatcagattt
    82261 tagaacctgg ttccttttta gttgcttgat tacatgatgt gaagaacatg tgccacaata
    82321 cccactgcga agagggcaag gataatagtg attggagata cttttttctt aagtaagtac
    82381 atgcaaagta aagtaaggag tagtcctgat aatccaggaa tcaacatatc caagttttgt
    82441 tggaaagtag taactttttc aggagtttga gacaatcctt gtcctacttg tgcgaatgct
    82501 tcttggatac ctttagaccc ttctggcaat ttatcccaat ggatataagc cttttcatct
    82561 agttgaactt tagaaacatc gaaagcaaat ttaatattta cccagcgttg aacaaggaca
    82621 gcaagaatga acatcccaag gatagaagct cctttagtga tatcttgaag gataccacca
    82681 gacatatctt tagtgatttc tgatccagcc ttgtatccaa tctcttgaac ataccacaag
    82741 aatgacatac gaatcaagtt ccatgcaaca aagaagagga gtggccccaa gatattgcca
    82801 gtaagggcaa gtgaagcacc gagagatcca aggattgggc gtactgtaaa ccagaatact
    82861 gggtcaccga taccagcaag aggtcccatc ataccgattt taaccccttg gatagcagcg
    82921 tcatcgattt ccacaccgtt agcacgttct tcttcaagcg caagagtaac ccccatgact
    82981 ggagcagcta cgtatggatg agtgttgaag aactcaaggt gacgctcaag agcagcgatt
    83041 tgatcttctt ttttagtata gagttttttg atagctggaa tgagtgtata agcccagccc
    83101 aagttttgca tccgttcaaa gttccaagac ccttgtaaga aggttgaacg ccaccaaact
    83161 tttttacgat ctgatttagt taattgaagt ttttcagtca tgatgttttc agtcctttct
    83221 tatcttagta gtcttctagg atatcgccga ttgggtcgtt agaagttgcg gctcctccgc
    83281 caccatttcc accagtttta gaaaggtgaa ggtagataag agcgatagca acgccgatag
    83341 caccgaatcc gattagagta atatctgaca cagcagcgag aacgaaacca agagcgaaga
    83401 atggccatac ttcacgagtt gccatcatgt tgataaccat ggcgtaacca acggcaacga
    83461 ccataccacc accgatagcc ataccatctt tgagccagtc tggcatggca ctaaggatac
    83521 tttgtacagt ttcagttggt accataagga gaagagctgc aggaagcgcg atacgaagtc
    83581 cttggaaaag tagcgcgatg aaatgcgcac gctccacagc gccgaagtca ccttttttag
    83641 cggcagcatc tgcagtatga accaaaccaa ctgaaattgt acgaacaatc attgtcaaga
    83701 aaagtccagc tacagcaaga gggatagcaa ccgcttgggc aacaccgata ccagtcttgg
    83761 taaagtcacc accaagaacc atgataatgg cagcagcgac agaagcaagt gcagcatcag
    83821 gagcgatagc agcaccgata tttgaccaac caagggcaat catttgaagc gatccaccga
    83881 ggataatccc tgcttccaag tgacctgtta caagcccaat aagggtacag gctacaagtg
    83941 gttggtgaaa ttggaactgg tcgaggatgc cttcaagacc tgcaaagaag gctacaacga
    84001 ctactaaaac catagaaata atagacatgt ttaaaatcct ttcataaata atggcttatt
    84061 tgacattggc tttgttaatc aagtcaaaca aatctttttt agaatcattt ggtactttac
    84121 ggacatcaaa ttcaacaccc aagtcacgca ttttttcaaa tgtagcaacg tcttctttgt
    84181 ccatagacaa aacggtattg accaatgttt tacctgttga gtgagccata gaaccaacat
    84241 taagagtctt gattggcacg ccgccttcga tggcacgaag ggcatcttga ggtgtttcaa
    84301 acaagataag ggcatgtgtt tctccaaaac gtgggtcttt tgaaatctca atcagttttt
    84361 gaattggaac cacgttagcc ttgacattac ctggagctgc ttgtttaatc aattctttac
    84421 gaaggtcgtc tttagccacg ttatctgaag caacgatgat acgatttgct tttgaatctg
    84481 gagtccaagc agttgcaacc tgaccgtgaa gtagacgtgt gtcaagacgg gcaagattga
    84541 ttttcaattt accgtctccg ataacagttc cttctgggat agcagtttgg gcaactggag
    84601 cagctgcagc gcttgcaact tcttcgactg gatttagctc ttctggaaga gctttgatgc
    84661 catctttggc ttctttaatg atattagcag cgactttttc tacacctgca gcagcgtcca
    84721 tgaggcgctc tgtgtaggct tgaatcaaca tcggtaagtt aagtcctgtg atgatggcaa
    84781 acttacgctc aggattttct cccatcacgc gactagcttg gttaaatgga gaaccactcc
    84841 aaaggtcagc caaaactaga acctcatctt ctgcgtcaaa tgcagcaaca gcgttattaa
    84901 acttagcgta tagatcatca ggaccttcat ttggcataaa ggtcacaact tgaacctttt
    84961 cttgttcacc aaagatcata gatcctgact gatgaatacc cgcagcaaat tcgccgtggc
    85021 tcgcaataat gattccgata ctcattattg tcattcctcc ttttttgttt tagttttcat
    85081 ttaagaaaac tttaagactg tttaagtata aaccgttttc ataaaaaaag caactattta
    85141 tcataaaaaa ttaaaaaatt tttatttttg tatgttgata tgttgagttt ttgaggagta
    85201 atcttgaatt cttatttaaa atttaatata aaaaagttgg aagaagcttc caacttttaa
    85261 aataggtttc tattagatta gtgggtgaag tcgagtacca tacgtccttg gatttggcct
    85321 ttttccattt cgtcgaaaat ggcaacagca tcttctactg gacgtttttg aacaactggg
    85381 actaccagac cttctgcacc aaattggaag gcttcttcta agtctttacg agttccgaca
    85441 agagaaccga tgacttggat tccatcgagg actgttttaa cgatgctgag ttccatcatt
    85501 tcagaaggaa gaccaacagc gacgacgcga ccaccagcac gaatggagtc aacagcctgg
    85561 ttgaaggcaa ctttagacac agcagttacg acagctgaat gagctcctcc atcagttttt
    85621 tctttaatga gtccagctac atcttcaact tcgaggccgt taatcacaat gtcagcgcct
    85681 acttcttttg caagggcaag tttgtcattg ttgatatcga ctgcgataac atgagcattg
    85741 aatacttttt tagcgtattg aacagcgagg ttaccaagtc caccagcacc gtaaagaaca
    85801 acccattggc ctggttcaac ttttgcttct ttgatagctt tataggttgt tactccagca
    85861 catgtgatag aagaagcttg ggctggatca agtccgtcag gaactttgac agcatagtca
    85921 gcagttacga tacattgttc agccatacca ccgtctactg agtagccagc atttttcact
    85981 gtacggcaaa gggtttcgcg accagttgta cagtattcgc aagtgccaca tccttcaaag
    86041 aaccaagcaa cgctgacgcg gtcaccgact ttaaggcttt tcacatctgg agcaatctct
    86101 ttaacgatac cgataccttc gtgcccaaga acacgtcctg ggacttgacc aaagtcacca
    86161 tgagcaacgt ggaggtcggt gtggcaaacg ccacagtatt caacttctac aagtgcttcc
    86221 ccagtttcaa gtggacggag tactttttct tcaatagcaa caccagtgct ttctggattt
    86281 acaacaacag ctttcatagc tatcctcctt gatattgacc gagaacaggg acaacgggac
    86341 tggattgatt ttttgtcaac agagtcgagt gtgacgagct ctcttgtatt tatatgtgaa
    86401 gtatatcaca aaagaaagcc ttttccaagg ttttggagac aaaaagtaga acaatcgatt
    86461 aactggttga tgagactgtg aaaagagcac aaagaccagc ttgcaagctg gtcatactct
    86521 tcgaaaatct cttcaaacca cgtcagcttc atctacaacc tcaaagcagt gctttgagca
    86581 acctacggct agcttcctag tttgctcttt gattctcatt gagtatcagt ataggttata
    86641 agaataagtc ttgtagggtt ttggcaaccc catcttggtc gttggtaagg gaaatttgct
    86701 catctgcata agggagtagc tctggattgg catttttcat ggcataaccc ttcccagcaa
    86761 aagcgagcat ttcggtatca ttgtgttcat ctccaaaggc aatcaaatct tttttgtcac
    86821 gattcattat cttgagcaag tagtccaaag caaaggcctt gttgacacct tttggggtac
    86881 attcaaggat attgagcgga cctccccagg tattgataga aagttgatgc tggtagaagg
    86941 cgttcatgtc ttttgccaag gcatatttgt cactggctct ggtctgcaag aggatacagt
    87001 tagggtcctt ggtcaccaat tcaggctgga attgatcttc aggctggaaa gcttctacac
    87061 caaatagttt gggattggca atttcttcat tgggatttgt aatgtagaat tttttacgat
    87121 attctccagc gataaaatcg gcttgaatgt cctctgaacg ttgaaccata tctagcagat
    87181 attttttgtc tacagtcaaa cacttttcaa aatcccaaac ttggtctggt aaatgagtaa
    87241 gggatccgtt gaagttaatc ataggagtgt ctaagcccag ttcacggtaa aaatcttttg
    87301 acatacggta agggcgacct gtcgtaataa taacctgatg gcctttttca gcaacttttt
    87361 tgatggtttt tttggtaaag tcagaaattt gactgtctga gttgagcagg gttccatcca
    87421 ggtcaactgc aataattttt ttcgtcatat ggacctttct agtgtgtttt cagataagat
    87481 gtcttctatt ataacagaaa gcaggcagaa aagcagattc caaacaaaaa atgaaattgg
    87541 attaatttct taaacaaatc aaacaaagac attgaaaaag tgaatgataa atgatataat
    87601 tctattattg ttcgtaaaaa ttaaaaggag attgatgatg gacaaattat ttaaactaaa
    87661 agagaacggt acagacgttc gtacagaggt tctcgctggt ttaacaactt tctttgcaat
    87721 gagctatatt ctctttgtaa acccacaaat actttcacaa acaggaatac ctgctcaggg
    87781 cgtcttccta gcgacgatta ttggtgcagt agcgggtacc ttgatgatgg ctttttatgc
    87841 taacttacct tatgcccaag cgccaggtat gggactcaat gccttcttta cctttacagt
    87901 tgtattcggg cttggttatt cttggcaaga agccctagct atggtcttca tctgtgggat
    87961 tatttcattg attattacct tgacaaatgt tcgtaaaatg atcattgaat cgattcccaa
    88021 tgctcttcgc tcagctattt cagctggtat cggtgtcttc cttgcctatg tagggattaa
    88081 gaatgctgga cttttgaaat tcacgattga cccaggcaac tatactgttg taggagaagg
    88141 ggctgacaaa gctcaagcaa cgattgcagc aaactcttca gcagttccag gattggtcag
    88201 ctttaataat ccagctgttt tagtggctct tgcaggactt gccattacta tcttctttgt
    88261 catcaaaggg attaaagggg gaattattct ctctatcttg acaacaactg ttcttgctat
    88321 tgcagttggt ttggttgatt tgtctagtat cgattttgct aataaccatg ttggtgcagc
    88381 ttttgaagat ttgaagacaa tctttggtgc agctcttggt tcagaaggtt tgggagcttt
    88441 ggtttcagat acagctcgct tgcctgaaac tctgatggcc attcttgcct tctcattgac
    88501 agatattttt gacacaattg gtaccttgat cggtacaggt gaaaaagttg gtattgtagc
    88561 gacaaatggt gaaaatcacc aatcagccaa attggataag gctctttact ctgatttgat
    88621 tggaacgaca gtcggtgcca ttgcaggtac ttcaaacgta acgacttatg ttgagtctgc
    88681 tgctggtatc ggtgcaggtg gacgtactgg tttgacagcc ttggttgtag ctatctgttt
    88741 tgcgatttca agcttcttta gcccgcttct agcgatcgta ccaacagcgg ctacagctcc
    88801 aatcttgatt atcgttggga ttatgatgct tggtagcttg aaaaatatct attgggatga
    88861 tatgtctgaa gcagttcctg tcttcttcac atctatcttt atgggattca gctactctat
    88921 cactcaaggg attgcagttg gtttcttgac ttacactttg actaagcttg tcaaaggtca
    88981 agttaaagat gttcatgcca tgatttggat tttggatgcc ttgtttatcc ttaactacat
    89041 cagcatggcc ttataataga atgacccagg gggattttcc ccctttttta atacaaagga
    89101 gataggtgat gaaagagaaa aatatgtgga aagaattgtt gaatcgtgca ggctggattt
    89161 tggtcttttt acttgccgtc cttttatatc aggttcccct agtggttacc tctattttga
    89221 ctttaaaaga agtagccctg ctacagtcag ggctgatagt tgctggcctt tcaattgtgg
    89281 ttctggctct atttattatg ggagctcgta aaaccaagtt agctagtttt aatttttctt
    89341 tttttagagc taaagatttg gcacgtttgg gcttgagtta tttagttatt gtcgggtcaa
    89401 atatacttgg ttctatcttg ttgcaactgt caaatgagac gacaacagct aaccagtctc
    89461 agattaatga tatggttcaa aatagttcgt tgatttccag tttcttcttg ctagccttgc
    89521 ttgctccgat ttgtgaggaa atcttgtgcc gtgggattgt tcctaaaaag attttccgag
    89581 gcaaggagaa cttgggattt gtagtcggta cgattgtgtt tgctttattg catcaaccaa
    89641 gtaatttacc ttctttattg atttatggag gtatgtcgac agttctatct tggacggcct
    89701 acaagaccca acgtttggaa atgtcgatct tgcttcacat gattgttaat gggattgctt
    89761 tctgtttgtt ggctcttgtg gtgattatga gtcggacatt aggaatttct gtttaaaagt
    89821 ttttatgtag gaaccgacct ctttctacta gggaaagatg aatgcaatcg tgtccatctt
    89881 tttcttttta tggtaaaata gaaaaataat atgatgaaaa tccttgaggg agtgaccgat
    89941 atgtcaagta aagccaatca tgcaaagaca gttatttgcg gaattatcaa tgtaacccca
    90001 gactcctttt cggacggtgg tcaatttttt gctcttgagc aggcactcca gcaggctcgt
    90061 aaattgatag cagaaggagc cagtatgctc gatatcggcg gagaatcgac tcggccgggc
    90121 agtagctatg ttgagataga agaggaaatc cagcgtgttg ttccagtgat caaagcgatt
    90181 cgcaaggaaa gtgatgtcct catctctatt gatacttgga agagtcaagt agcagaggct
    90241 gctttggctg ctggtgccga tctagtcaat gatatcactg gtcttatggg tgatgagaaa
    90301 atggctcatg tggtagctga agcgagagcg caagtggtca tcatgtttaa tccagttatg
    90361 gcgcgacctc agcaccctag ctcgctcatc ttccctcatt ttggttttgg tcaagctttt
    90421 acagaggaag agttagctga ctttgaaaca ttgccaatcg aagaattgat ggaggctttc
    90481 tttgaacgag cactagcgag agcggcagaa gctggtattg caccagaaaa tatcctgttg
    90541 gatccaggaa ttggctttgg tctgaccaag aaagaaaatc tgcttctttt acgggacctg
    90601 gataaactac atcagaaggg ctatccaatc tttctcggag tgtcgcgcaa gcgatttgtc
    90661 atcaatatcc ttgaagaaat tgggtttgaa gtcaatcctg agacagagct tggtttccgc
    90721 aatcgggaca cggcttcggc tcatgtaacc agtatcgctg cgagacaggg tgtagaagtg
    90781 gtgcgcgtgc atgacgtagc tagtcacagg atggcagttg aaattgcctc tgccattcgt
    90841 ctggctgatg aagcggaaaa tttagattta aaacaatata aataagatga aagaaattga
    90901 aaacaatcag tggattgcta actaccggac ggatcaaccg cattttggct tggaacgaat
    90961 ggtggaactg ttagctttgc gtggcaatcc ccatctcaaa ctcaaggtcc tccatatcgg
    91021 aggaactaac ggcaagggct cgactattgc ttttttgaaa aagatgctag aaaagctagg
    91081 gctgagagtt ggcgtgttta gctcgcccta tctcattcat tacacagacc agattagcat
    91141 caatggggaa tcgatctcag aagcgaggct agaagctctc atggcagact atcagtcttt
    91201 gctggaggga gaagcggtcg ccaatttaca gggcacaacc gagtttgaga ttatcacagc
    91261 cctggcctat gactactttg cctcagagca agtagatgtg gccatcatgg aagttggcat
    91321 gggtggactt tttgatagta ccaatgtctg tcagcccatt ttgacaggaa ttacaactat
    91381 tggcttggat catgtggcct tacttggtga cactttggag gccatagcag agcagaaggc
    91441 aggtattatc aaacaaggga tgcccttggt aacagggcgt attgctccag aagccttggc
    91501 tgtgattgac cgcattgcgg aagggaaaga tgcgccgaga cttgcctacg ggacagatta
    91561 tcaggttcgt catcaagaaa gtgtggtgac aggggaagtc tttgactata caagtgctgt
    91621 cagacaaggt cgcttccaga ctagcctgct tggtttgtac caaatagaga atgctgggat
    91681 ggccatagct ttacttgata ctttttgtca agaagatggt cgagagctag caagcaatga
    91741 ctttcttggt caagccttgg aagaaacaag ttggccaggg cgtttggaaa tcgtgtcaag
    91801 agatcccttg atgattttgg atggagccca caatccccat gctatcaagg ccttgttggt
    91861 aaccttgcaa gaacgttttg cggattatca taaggaaatc ctcttcactt gtatcaaaac
    91921 caaggccttg gaggatatgt tggacttgct gggagccatg ccagataccg agcttactct
    91981 aacacatttt gcggatagtc gggcgacgga tgaaagcgtg ctgaaagagg cagctaagtc
    92041 tagaaatctc agctaccaag attggcatga ttttctagag cagaatttga cagataaaaa
    92101 agaagagaaa caaacaatta ggattgtcac aggttccttg tatttcttga gccaagtgag
    92161 ggcctatctg atggagagga agaacgagaa tggatacaca aaagattgaa gcagctgtaa
    92221 aaatgattat cgaggctgta ggagaggacg ctaatcgcga gggcttgcag gaaacacctg
    92281 ctcgtgtagc ccgtatgtat caagaaattt tttcaggtct tggtcaaaca gcagaggaac
    92341 atttgtcaaa atcctttgaa attattgacg ataatatggt ggtagaaaag gatatctttt
    92401 tccataccat gtgtgaacac cacttcttgc cattttatgg tagagcgcac attgcctaca
    92461 ttccagatgg tcgtgtggca ggcttgtcta agctagcccg tacggttgaa gtttattcga
    92521 aaaaaccaca aattcaagaa cgtttgaata tcgaagtggc cgatgccttg atggactatc
    92581 taggtgctaa aggagccttt gttgtcattg aggcggaaca tatgtgtatg agtatgcgtg
    92641 gtgttagaaa accaggcact gcaaccttga cgacagtagc tcgtggtcta tttgaaacag
    92701 ataaggacct ccgcgaccaa gcttatcgtt taatggggct ataaaaagaa tccgcttcaa
    92761 gcggattttt ctagaaagga atcattatgg atcaactgca gattaaggat ttggaaatgt
    92821 ttgcctatca tggtcttttt cctagtgaga aagaattggg gcagaaattt gtcgtttcag
    92881 ccatcctatc ctatgatatg accaaggcag ctacagactt ggatttaaca gcctctgtcc
    92941 attacggaga attgtgtcag cagtggacga cttggtttca ggaaacgagt gaagatttga
    93001 ttgaaacggt agcctataaa ctggtggaac gtacctttga gtcttatcct cttgtccaag
    93061 aaatgaagtt ggaactgaaa aaaccttggg caccggtgca tttgtcacta gatacttgct
    93121 cggtaaccat tcatcgccgc aagcaacgag cctttatcgc cctaggaagc aatatgggag
    93181 ataaacaagt aaacttgaag caagccattg acaaactgcg agctcgtggc atccatattc
    93241 tcaaagagtc cagtgtctta gagacggagc cttggggtgg agtggagcag gatagctttg
    93301 ccaatcaagt ggttgaggtg gaaacctggc taccagcaca agacttgtta gaaaccttgt
    93361 tagccattga gtcagagctg ggacgggtga gagaagtgca ttggggacct cgtttgattg
    93421 atttggactt gctctttgtg gaggaccaga tcctttatac agacgacctc atattgcctc
    93481 atccttacat agcggaacgc ctttttgtcc ttgagtcctt acaggaaatt gcgcctcatt
    93541 ttatccatcc gatattaaaa caaccgatcc gcaacttgta tgatgctttg aaaaaataga
    93601 aaaactctag ttttcagtta cttgcaactg aaggctagag tttttaaaat aggtcatttt
    93661 cttctgggag gaggatagtt tctctaccgt ccatgtctaa aaccagtact cttgggggat
    93721 aacgagggtc gaaaggatgg ttaaagtcaa aatcaatggc tgtagggagg tgttgacttg
    93781 aaaagtggaa ggtaatcttt ccttggttat taagcaattg aaactcgagt tcttcttcca
    93841 attcaaagac attttttaag aaatggtcga tgatatacca aaaagagtca atgatgtcat
    93901 caggcaagct ggtaacaatg ccaaaactag cagatcgcat gtgggtattg gtaaaagcca
    93961 tatctctgtc ccctttcttt tcccttatca tacagcaaat aggattaaaa atcaagaaaa
    94021 ggtgattttt tgaaaaggat tttagttaca gggagaaata gggaaaaaat tcctaaaaat
    94081 ctaccgaagt taataggtaa attcccaaat taacttgatt atataacttt cagttacttt
    94141 gagaagttac cgaaaaatat ttttcatatc tattgacttt taggggtaaa atttggtatg
    94201 atagtaggcg gtattgttta ccccatttga aaggccccgg aaccttccaa atacttttcg
    94261 atgggaagga acacccatca ccgtaaacaa aaatcgaact atatatagga gaaatcatga
    94321 acaaaacaac atttatggct aaaccaggcc aagttgaacg taaatggtac gtagttgacg
    94381 caactgatgt accacttgga cgtctttctg cagtagttgc tagcgtactt cgcggaaaaa
    94441 acaaaccaac atttacacca cacactgata caggtgactt cgtgattgtt atcaatgctg
    94501 aaaaagttaa attgactggt aaaaaagcaa ctgataaaat ctactacact cactcaaacc
    94561 acccaggtgg attgaaacaa atctctgcag gtgaacttcg ttctaaaaat gcagtacgtt
    94621 tgattgagaa atcagttaaa ggtatgcttc cacacaatac acttggacgc gctcaaggta
    94681 tgaagttgaa agtatttgtt ggagctgagc acactcacgc tgcacaacaa ccagaagttc
    94741 ttgacatttc aggacttatc taaggaaagg aacaataaag tatgtcacaa gcacaatatg
    94801 caggtactgg acgtcgtaaa aacgctgttg cacgcgttcg ccttgttcca ggaactggta
    94861 aaatcactgt taacaaaaaa gatgttgaag agtacatccc acacgctgac cttcgtcttg
    94921 tcatcaacca accattcgca gttacttcaa ctgtaggttc atacgacgtt ttcgttaacg
    94981 ttgtaggtgg tggatacgct ggtcaatcag gagctatccg tcacggtatc gctcgtgccc
    95041 ttcttcaagt agacccagac ttccgcgatt cattgaaacg cgcaggactt cttacacgtg
    95101 actcacgtaa agttgaacgt aagaaaccag gtcttaagaa agctcgtaaa gcatcacaat
    95161 ttagtaaacg ttaattcgaa agaattacta tacttataca gagcaccttt cggggtgttc
    95221 ttttttatac tttcttacta aattggtgca attgacacag ttgttgcgac tttagtcgct
    95281 tacaaatgtg gctgcaacct gacaaggtca gttgcctcaa aacgttaatc aactcgatta
    95341 tatcaacgtt tcgaagcact cacaggtttg ccctatgggt gcttttttct atactttcta
    95401 caaaagtttg ccctaaaatt tgccctaaat tttccctact tgtttttaag atgttggtag
    95461 gcaacttgtc cagcaaataa tggaactatg tttgaagtat taacataagt cttcgttgta
    95521 attgtatcgc tatgagttaa tgcttcagaa atggcttcta agctcattcc tgctttttta
    95581 gcaagtgtcg ctcctgtatg tcgtaattta tgaggtgtag cgtgttttaa ctttgggtgt
    95641 cgtcttttta cggagttcat tttgttattg agataatcaa cgtgtagagg gctatttaca
    95701 ttacctttcg tatctatata ggtaaagact agttgatcgg atgtttgcat tataccaaat
    95761 ttcgctaact catatttctg ttgttttttc cattctgaaa gaagtgatac aaggtaacta
    95821 ggaattgaaa aaatcgtttt cttatttcct tttgttgact ttacattctt atatttgtca
    95881 agtgcatgcc ttaagtcaat ttgagcattt gccaagtcta tgtttttcca atgtaaagca
    95941 taggattctg attttctatc gctcaaaata aaggttgtaa agaataggac ataatctttt
    96001 agtgataatt tatcgttctc caaatcttct ctaaaagcat caaaccaatc ttgtaattct
    96061 tcactagata gatacaagtc ttcctcattt ttggattctt ggagttttag ctttttggta
    96121 gctttaattc gtttaattgt cttggataat cgatttgatt ctatgtactc caattcctca
    96181 gcccaatcga aaattgagtt tacatagctt cgaataactt tgaaattagc atactcttca
    96241 gctttagcag tcattaagtt tagtacgact tgcttattct gattcagaaa attgattgaa
    96301 taattaccga acattggtaa aatatgcttt ctgaaaacag tttcagtatt atcgatagta
    96361 gcctgtgttg gaggcttagt tgttgaagtt gtttgaccag ctttgtatga atcccaccaa
    96421 atattattaa agaactcaga gaaaagaata tcactagttt tagggagtgg gatatcctct
    96481 ccattttcaa gttgatgtat ctttgttaga atttctaatt cagcttcttt agcctccttt
    96541 cttgttttat agcgtttaac aaagtgattt ccttaaagat ataaatactg atttcccgct
    96601 tcctgtacct ccggcaacta gaatatgagg acacttgata ggattataat tcacaccgta
    96661 tcctaaatct atattaaggt tatctatctc ttgcttctgg ttgtgagatt gaagaactaa
    96721 cctgtcaggt ttcttgtaat agaaatggta ttccataaaa ctaggacgaa taattttgta
    96781 ttctagttcc agttcgagta ctccagcaag aacatcatca agtgattgta cccttttact
    96841 aaattcatca ccagtaatca gagctttgat aaagatatgc cccttttgtt tgtctaactc
    96901 gtattgtaag attgcgctcc tagagatttt ttcatatcct gagctatctt tatgtgttgt
    96961 ataaaggcgg tttgtatgta atacatacaa taagctttct ctgataatta ggtaataatc
    97021 taaattatat ctaaaatatt ttaattgacg atgaaatttg tatatgacaa atcctactag
    97081 aataagtaaa gggattttaa taaggtcagg ggctctaata tttgcaataa tagtaagcat
    97141 aatgcagata gagaggctta atattgacca atgagttact tttaatttgt tagttgaaat
    97201 gatataattt ctttttaagt cagcgacttt ctttaattta aacatagatt acctattttt
    97261 ctagatttat tagtagtaca acaaatatac attttaaaga aatgaaaatc taaacagtag
    97321 aactgattag attagtgttg ttctttccag taggaatata caacaagttt gataatgtag
    97381 ctaagacgag gtagtctagt agcacagtcc tctttcatca aaacatagcg aaaatcatca
    97441 agcccagcaa gcacatcctc gtctagataa atacggggag taactgtggt ttctaagtta
    97501 ggattaacat tttttacgtc cctttccatc tgctgacgta gcttttgcca tttgtcaatt
    97561 tgatagtgtt tagtatttcg ataggattct tctatgacac tccctattga ggcttttaga
    97621 atgatattaa atgaaagacc attcaattca tcatagtgat ttttaagaag tgttttttca
    97681 agtttatcta gaaaatcctc tttattaagt tcttgaattt tacgttcttt ttcttgaatc
    97741 aattcatcta tccatacctt tgcctcgtac gcaaggcgga cgcttttata tactctagtc
    97801 attgtttcct ctcttgttca aattcatttg agtatttaat tttatccata ttttcaattt
    97861 ccttatagaa atggaaatct tttttattta gtttatcgca tatttgttta atgatgaatt
    97921 tcccgcgctc ctcaatccgt tcattgactc tttttaggaa gatggagaaa tcttcggttt
    97981 tcttgggata aatgtattcg tagttatgag tttcccaaaa tacctctgtt tgatagttat
    98041 tatcaacata gggttgaaga tagtatgtat caataaaatt tttccatgct tgaggagata
    98101 aattagtaag ccattcttga agagaaagca ttgtaatatc ccagtaatct tttgagaaat
    98161 tgtatcgtcc agtattcatc caatgaggca atacagtaaa gtttccgatt gtatgtgtta
    98221 attttgcgaa tgcttcaaat tcttttaggt ttttttgaat catcttgaaa ttttgatagt
    98281 ttttattatg gtgtaagatt ggatactgct tgtttagata ttcatttaag tttactccaa
    98341 tctttttaca aatttcttta taattcgggt cattggtaat agcttgagta aatgtagtta
    98401 tataagaatt taaggtctca cctcttatta tatctctctc ggaatgttgc caacctaaaa
    98461 cattataaag tgggagtgcc tctttatcgc agtcagcgtt actaccaacc tgttttgtga
    98521 tacaaaatgt ggaaggattt acgagttctc catttttata ttttagaaaa tttgaaatat
    98581 tatctgcggt taactcgcta gagtaacaat ttttaaaatc ccataaccat ggtttgatat
    98641 cgttttggtc acagtaattt aaccattcaa taacttttgt gttatccata attctaccta
    98701 ttctattttg ttgtaaaaca actatacttt tattataact attttttcag aaaatgcaag
    98761 agatttagaa aaaaattttt tcaaatattt ttttgtggat tgtaagttat ggctatattt
    98821 aaatttcata gcgttaaatt tcagaatatt tgttataatg aactatataa gtaattgagg
    98881 taaatatata tatgaaaaaa gtaattgaaa tgttcccaga atttcaccaa gagaaattag
    98941 aaacaactga tataaaagat gaaaataatt taattgtagt tgatacaaat tttttattac
    99001 agattttaga gttgccaatt gatatagcta ctaagtatgt ggattcatta aaatcaataa
    99061 agagaaatct ttatatacct tatttagtcg ctcttgaatt tcattttaat aaaagtaata
    99121 aaaagaaaac taaaaagaga aatgcagact catactttaa acaagttgaa tctgcattga
    99181 atcaattaaa atcaagtgta cagaatactg atttaattaa aatggatatt gagaatggta
    99241 aactaaaaca tttgattggg aatttggagt tttttactga tgattttttg gctaaggtga
    99301 atttatttgt aagagatgaa attactgata aagaagatga agtttataaa gagttactta
    99361 atattatttc tgattctatt ggagatgtgt atgagcagga atggatatat gaaatagaaa
    99421 aagaaggaga aaaacgtttt gcagaagcta ttccaccggg atttaatgac gaaaataaag
    99481 atggaataag aaaatataat ggcatatctt atcatcaaaa atatggtgat ttaattattt
    99541 ggaaggatat attaaaaaaa gcaacggaac aacctcgtgg tgataaagtt atctttatta
    99601 ctaatgacgg agaatcaaat aaaaaaagtg atttaattta taaaacttca aatatgaaag
    99661 ttggtccaag tattttcttg atgaatgaat tatatatgtg tagtagaaaa aaattatata
    99721 tattaaacaa tactacactc gtaaacatga ttacagagtt atcagaagat gaaattgata
    99781 ggatagaggc ccaggaagaa aagaagtatg ttgttacgtt tccaaaatgg attttagata
    99841 aagcagaaaa agatgtgcga gcaagaaatg agtcaaataa ctcgagtgtt gtatattata
    99901 ttgattcaga aaataggtta gctagcattg atattgatga agttgaaccg cttgaactca
    99961 tatccctgct agagaatcct gatgtaaaaa aaatgttaaa agaagaaatt ttgaagaaaa
   100021 tgttagatgg ttattacagt aaattaccaa gacatattat taaagacata ataaatagtt
   100081 atcaagaaaa aaatattcaa tgaatttaat aataaaattt catcatttag ggcaaattac
   100141 tgataaagct gactcgtttt ggttggtttt gtagaaaaat ttgccctatt tagatgaaaa
   100201 tggttgaaat tagttgagaa ctagtaaata tttggtagtt aaaaatggtt tgattaaagg
   100261 taattgaaag aacttagtta ttaggttagc caaaccaggt cttaagaaag ctcgtaaagc
   100321 atcacaattt agtaagcgtt aattcgaaag aattactata cttatacaga gcacctttcg
   100381 gggtgttctt tttttatact ttcttactaa attggtgtaa ttgacacagt tgttgcgact
   100441 ttagtcgctt acaaatgtgg ctgcaacctg acaaggtcag ttgcctcaaa acgttaatca
   100501 atacgattat atcaacgttt caaagcactc aaaagttcac cttattttta tagtaaaatg
   100561 aaataagaat aggacaaatc gatcaggaca gtcaaatcga attctaacaa tgttttagaa
   100621 gtagaggtgt actattctag tttcaatcta ctatacctta ttgttttaga gactttaaag
   100681 caaattcacc tactgtcata ggaactacat tagaagtatt tacataaatc tgtgttgttc
   100741 ctgtgtcact gtgtgttaga gccttagaaa tggcttctaa gctcattcct gcttttttag
   100801 caagtgtcgc tcctgtatgg cgtaatttgt gaggtgtagc gtgtgtcagt tctttatgtc
   100861 gctttctaat gcttttcatt ttattgttca gatagtcggc atgtaaaggc ttgttgatgt
   100921 ttccttttgt gtcgatatat gtaaaaacaa attgttctgg attactgagg atgccaaact
   100981 ttgctagttc atatctttgt tgttctttcc aagaggtaag aagttgaagt aaatcattag
   101041 aaatagagaa aaataggata gcaaaagctc tatttcagga gaaaatgaag caaatatttc
   101101 cataataaaa cgcatattat caaggttgtt caatacctga tactatgcgc ttttctgatt
   101161 ttaaagactg attgctcagt ctctttttca ttataattca gttacaattt aatcttattt
   101221 gagaaagtgg gtgatgctat tctctaataa gactatgata ttaatttttg atagtacttc
   101281 cagaaattat agatcccctt tcatccccaa tttctatttt caagtgtccg tattatatag
   101341 cgtattcgaa attcactata tcttgttagg atttgggtag aatcattgat aacagactgt
   101401 tgcaaatcta attagctgta tgatttatat ttatctattt ttctagtaac caatctataa
   101461 tgtttttctt ctcgattcca ttgtaattgg ctgttggctg aatcgtatcc attgttaata
   101521 gatactttgg gaattgatct ttaatggcgt ctagtggtct aagttctctt tctagtgttt
   101581 ctggagcaag tgttgtttca ctgacttgat aataagcgta gtgaccaaga tcagttacaa
   101641 caacaaaatc aacctcatat ttatctaaat taccaacata tacttgtgaa tatctacgtc
   101701 tcaattccaa atagaccata ttttccaaga tatggccaat atcttctttg tggtctggca
   101761 ataagaggtg tcgtaaacct aaatcaacgg gataatattt ttctaagcgt tgcaataatg
   101821 ctctaccttt tacatcaaaa cgtggaacgg aataaaaaag caaactatct gtcaaagtcg
   101881 tcaaataatt ttccaaagta ttatgggaga ttgaaacgtt ttggctgacc agggtattgc
   101941 gaatcttatt tgttgatatt aagctacctg tactactgag aagggttcgg acaatgcgct
   102001 caataatagt aggatttgga tttcccaatc tagtgacaat atcatttaac agtatggagt
   102061 tatatattcc tcttagataa tcaatttttt cagcgtaaga tgatgtttgc aataagtaag
   102121 ggaaagcact aaagagataa ttgttaaaaa tttctgttgt attcagattt tctgtgagag
   102181 attgacctga tagatattct tcaaatgaca atggaagaac ttctatctca acataccgac
   102241 cggtcaagtt tgtagctaat tggctactca taaagtaggc gtttgatcca gtcaaataga
   102301 ggtcaacatt tggtagtata aatagactat ctgctaccag ttcaaatttt tcaacatgtt
   102361 gaatttcatc taaaaagata tagtatgttt tctctccaat taactgctct tttatataag
   102421 caaataatgt ttgaaaatgt cggagatcat agtaactcag atcctcaaaa ttgatggata
   102481 tgatttgatc ctcgtctacc ccagttgcta ttaactcctc tttatagagt tgaaagagaa
   102541 cagatttacc agctcgccta actccactca caactttgat gatttgtcgg tcacgatgtc
   102601 ttcttaaaaa atctaaataa tgtggtcttt tgatatagtt cataatagtt acctcaaaga
   102661 tagtataata caaatagatg ttattttcaa atatttagaa ataatgttta atttatttaa
   102721 ttatttctaa ttgtttagaa ataatatctg gaactattta aatatcttca agatagaaaa
   102781 agaaattgta cttgttgatg ttgaatcatt tgtgttaaca agtcatttag aagcatttaa
   102841 gaaattagtg aaatgaaaaa ctcatggcag aacaaattgt tgggtatatg gtctattact
   102901 aacaactact gctagtttat gagatagata tttaattatt ctcggataaa taggataagc
   102961 gtgctgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca tagaaacatg
   103021 gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga aaagatgaca
   103081 atcatgggaa tagcttttga aaacagatcc gtttttaaga gtgtttggta tgctttaagt
   103141 acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt acgagatgaa
   103201 gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgaatcttat gactatgttg
   103261 atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag caggaaggaa
   103321 aaaagcacgt gagcttgaat atcgtatgat tgctagtaag agtttgaaat tatttatcaa
   103381 tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag cttagaaaag
   103441 ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt tgtccactgc
   103501 attttttcaa ttgactatta tttgtcatag atataacaga tagaacattg cattcagaat
   103561 aatgaaaaac gcatcaaaaa tggtgcgttc tgtttttatg ctaccataaa aggaggaaaa
   103621 caaattgaaa atttttaagg gagagtttta tcgaatctct gtattaacag acaagctagt
   103681 aaggttagaa tactctcgaa ctggaaattt tgaggataga acgacacaac ttatctataa
   103741 tagagatttt ggccaaattt cgttagatta tatcgagaca tcaaatgtac tagatattat
   103801 gacggactat tttcatctgc actttaataa aggagaattt aacgccgaaa atttatttat
   103861 agaattaaaa ggaaattttg ccgtatatgg tagtcgctgg tattttggtg aatctattga
   103921 aacgttaaaa ggaacagctc ggactctgga taaggcagat ggagcaatct cgttagaaga
   103981 tggaattatt agccgaaatg gtatagcctt attggatgat tctcaaggat ttatttggga
   104041 tgaacagtct ggttatattg agagagaaaa tcaaattgac ctgtatttct ttgcctatgg
   104101 gcatgattat agaggagcaa tcagagactt ttaccatttg actggttcaa cacccttgtt
   104161 gccaagatat gctttaggca attggtggag tagatattgg ccttatacgt cggatgaata
   104221 cttggattta atagacagat ttgaaacaga gaaaattcca ttatctatcg gtgtgttaga
   104281 tatggattgg catataactg acattccagc tcgttttgga agtggctgga caggatatag
   104341 ttggaataga aacttaatac caaatccaga acagttattg caacaacttc atgatagaaa
   104401 gttaaaactc tccttaaatg tccatcctgc tgatgggata cgggcttatg aagaagctta
   104461 tcctcaaatc gcaaaacgat tggggttaaa tgtagaacta gaagaacctg ctatttttga
   104521 tttttttaat ccctctttta gggaagccta ctttaaagat gttcattatg agctagaaaa
   104581 gcagggagta gatttttggt ggattgactg gcaacaaggg acacaaggta tgctagatcc
   104641 actttggctt ttaaaccatt atcactatca agatagttgt aaaaatgcag aaggtggttt
   104701 gattttatca agatatgcag gtcctggtag tcaccgctac cctgttggtt tttcagggga
   104761 tactattatt agttggaatt ccttaagatt tcaaccctat tttacagcga cagcatctaa
   104821 tatcggttat agttggtgga gtcatgatat cggtggacat atgttggggg attatgacga
   104881 agagctacaa actagatggc tacagtttgg tgtttttagt ccgattactc gattacatag
   104941 ttctagaagt ccttttaata gtaaagaacc ttggttcttt tcagaaacaa catctaagat
   105001 tatgaagaaa taccttcgtt tgagacatca gatgattccc tatctatata ccatgaatgt
   105061 aaagacacat gaggaaggtg ccccattaat cagtccaatc tattatttct atccagagaa
   105121 tgatgagagc tataatgttc caaaccaata cttttttgga acagaactga tggtggctcc
   105181 cattgtagaa aagatggatt tgacattcca atctgcaaaa gtagatgtat ggttccctga
   105241 aggtgaatgg tatgacttct tttcagagaa aaaatacaca ggtggtgtga agttaagtgt
   105301 ttatagggac atctcgacta cgcctgtgtt tgcaaaaagt ggtgcaatca ttcccttggt
   105361 tggttctgag ataggtatgg gtgttgattt acctgaggtt gtagattggt atgtattccc
   105421 agggaaacaa cattcttttg aaatgcttga agatcaaaat ggtcaaagat ataaaacaag
   105481 attatcaatc gattgggaaa tgggaatggt agagttagca ttacaaggag attctagtat
   105541 cgttccaagc aatagaaaac atagaattca ttttaaagga acgaatgtgt ctataattga
   105601 attgccaaat aagaatgata cagctaaatt tgaatggaaa gataataaaa ggacatcttt
   105661 aaatgacgaa gtttttagac tactaaagac agcttctctt ccatatgaat taaaagatag
   105721 attgttaaat caattcatca atgcgaaaaa ctctcatgac ttaatgaata tcttgcatca
   105781 tcaggataag gaattgagag ggcgtttgtt ggaaatgata tttactagcc aaaactaatt
   105841 gatataatta gaaagtcatt tgtttagtgt atatgaagat tctgtatggt attcgttatc
   105901 actggtcaca ttgaaaatgt gaaataagca cctacaacat agactttaca acacttcatg
   105961 tttcatatca tggggtgttt ttctatttaa gtcaaagcca atcaaaaaag g
//
LOCUS       DAVDHC010000004        97558 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVDHC010000004 DAVDHC010000000
VERSION     DAVDHC010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 97558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97558
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.004"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            74..652
                     /locus_tag="VUR43_000389"
                     /pseudo
     CDS             74..652
                     /locus_tag="VUR43_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            665..835
                     /locus_tag="VUR43_000390"
     CDS             665..835
                     /locus_tag="VUR43_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412131.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(1331..2677)
                     /gene="gdhA"
                     /locus_tag="VUR43_000391"
     CDS             complement(1331..2677)
                     /gene="gdhA"
                     /locus_tag="VUR43_000391"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET5412132.1"
                     /translation="MTSAKEYIQSVFETVKTRNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKIYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            3017..3650
                     /locus_tag="VUR43_000392"
                     /pseudo
     CDS             3017..3650
                     /locus_tag="VUR43_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            3653..4324
                     /locus_tag="VUR43_000393"
                     /pseudo
     CDS             3653..4324
                     /locus_tag="VUR43_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            4380..4898
                     /locus_tag="VUR43_000394"
     CDS             4380..4898
                     /locus_tag="VUR43_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET5412133.1"
                     /translation="MLSPAGAQESLSSYFVKITDASKAVKNGDQAEVQKLVTKMASDF
                     ERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLAFEKEQNPVDLDAEKEKLVNR
                     LSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNSTAHYGRVETAISFLPS
                     SMETEPTDESGT"
     gene            complement(4955..5239)
                     /locus_tag="VUR43_000395"
     CDS             complement(4955..5239)
                     /locus_tag="VUR43_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET5412134.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(5293..6228)
                     /locus_tag="VUR43_000396"
     CDS             complement(5293..6228)
                     /locus_tag="VUR43_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET5412135.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            6332..6775
                     /locus_tag="VUR43_000397"
     CDS             6332..6775
                     /locus_tag="VUR43_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET5412136.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            6891..7157
                     /locus_tag="VUR43_000398"
     CDS             6891..7157
                     /locus_tag="VUR43_000398"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET5412137.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            7154..7528
                     /gene="crcB"
                     /locus_tag="VUR43_000399"
     CDS             7154..7528
                     /gene="crcB"
                     /locus_tag="VUR43_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET5412138.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            7522..7851
                     /gene="crcB"
                     /locus_tag="VUR43_000400"
     CDS             7522..7851
                     /gene="crcB"
                     /locus_tag="VUR43_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET5412139.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            7970..8317
                     /gene="rplS"
                     /locus_tag="VUR43_000401"
     CDS             7970..8317
                     /gene="rplS"
                     /locus_tag="VUR43_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET5412140.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            8359..8430
                     /locus_tag="VUR43_000402"
     tRNA            8359..8430
                     /locus_tag="VUR43_000402"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8392..8394,aa:Arg,seq:cct)
     gene            complement(8597..9595)
                     /locus_tag="VUR43_000403"
     CDS             complement(8597..9595)
                     /locus_tag="VUR43_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET5412141.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(9638..10444)
                     /gene="yidA"
                     /locus_tag="VUR43_000404"
     CDS             complement(9638..10444)
                     /gene="yidA"
                     /locus_tag="VUR43_000404"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET5412142.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(10457..11761)
                     /locus_tag="VUR43_000405"
     CDS             complement(10457..11761)
                     /locus_tag="VUR43_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET5412143.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSISFSQEDQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            11833..12210
                     /locus_tag="VUR43_000406"
     CDS             11833..12210
                     /locus_tag="VUR43_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET5412144.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            12301..12633
                     /locus_tag="VUR43_000407"
     CDS             12301..12633
                     /locus_tag="VUR43_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET5412145.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            12645..14216
                     /gene="ffh"
                     /locus_tag="VUR43_000408"
     CDS             12645..14216
                     /gene="ffh"
                     /locus_tag="VUR43_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET5412146.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(14411..15694)
                     /locus_tag="VUR43_000409"
     CDS             complement(14411..15694)
                     /locus_tag="VUR43_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET5412147.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(15948..16661)
                     /gene="rsmG"
                     /locus_tag="VUR43_000410"
     CDS             complement(15948..16661)
                     /gene="rsmG"
                     /locus_tag="VUR43_000410"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET5412148.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            16755..17315
                     /locus_tag="VUR43_000411"
     CDS             16755..17315
                     /locus_tag="VUR43_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET5412149.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            17317..18216
                     /gene="htpX"
                     /locus_tag="VUR43_000412"
     CDS             17317..18216
                     /gene="htpX"
                     /locus_tag="VUR43_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET5412150.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRIFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(18260..19819)
                     /locus_tag="VUR43_000413"
     CDS             complement(18260..19819)
                     /locus_tag="VUR43_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5412151.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYESYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTE
                     HGLELVNLEDV"
     gene            complement(20058..20375)
                     /locus_tag="VUR43_000414"
     CDS             complement(20058..20375)
                     /locus_tag="VUR43_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET5412152.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            20545..21087
                     /locus_tag="VUR43_000415"
     CDS             20545..21087
                     /locus_tag="VUR43_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET5412153.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            21087..21716
                     /gene="nth"
                     /locus_tag="VUR43_000416"
     CDS             21087..21716
                     /gene="nth"
                     /locus_tag="VUR43_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET5412154.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            21927..22448
                     /gene="pyrR"
                     /locus_tag="VUR43_000417"
     CDS             21927..22448
                     /gene="pyrR"
                     /locus_tag="VUR43_000417"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET5412155.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            22467..23390
                     /locus_tag="VUR43_000418"
     CDS             22467..23390
                     /locus_tag="VUR43_000418"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET5412156.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            23440..24519
                     /gene="carA"
                     /locus_tag="VUR43_000419"
     CDS             23440..24519
                     /gene="carA"
                     /locus_tag="VUR43_000419"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET5412157.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            24832..28008
                     /gene="carB"
                     /locus_tag="VUR43_000420"
     CDS             24832..28008
                     /gene="carB"
                     /locus_tag="VUR43_000420"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET5412158.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTRLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAIAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(28283..29092)
                     /locus_tag="VUR43_000421"
     CDS             complement(28283..29092)
                     /locus_tag="VUR43_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET5412159.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(29094..29897)
                     /locus_tag="VUR43_000422"
     CDS             complement(29094..29897)
                     /locus_tag="VUR43_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET5412160.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(29907..31394)
                     /gene="tacF"
                     /locus_tag="VUR43_000423"
     CDS             complement(29907..31394)
                     /gene="tacF"
                     /locus_tag="VUR43_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET5412161.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            31750..32457
                     /locus_tag="VUR43_000424"
     CDS             31750..32457
                     /locus_tag="VUR43_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET5412162.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVLHAEDLVDKYLPLHKERIIITKGGADRNTSIENIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIKLAQNHDAVDTVVEAVDTIVESTNGQFITGIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            32462..33484
                     /locus_tag="VUR43_000425"
     CDS             32462..33484
                     /locus_tag="VUR43_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET5412163.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLL
                     LVGSSRSGRIDFENAIQMMKVKKFANRLKNILYLEEPVREIKDIHRIFATDLNTAFKT
                     VFKWEV"
     gene            33501..34367
                     /gene="licA"
                     /locus_tag="VUR43_000426"
     CDS             33501..34367
                     /gene="licA"
                     /locus_tag="VUR43_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET5412164.1"
                     /translation="MEKIIKEKISSLLSQEEVLSVEQLGGMTNQNYLAKTTNKQYIVK
                     FFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSIK
                     TKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLEK
                     RLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTSQ
                     EEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGADFGYYGVNRYQRAV
                     KGLASYGGTDEK"
     gene            34357..35235
                     /locus_tag="VUR43_000427"
     CDS             34357..35235
                     /locus_tag="VUR43_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET5412165.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTVVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            35247..35936
                     /locus_tag="VUR43_000428"
     CDS             35247..35936
                     /locus_tag="VUR43_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET5412166.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            36032..36880
                     /gene="dprA"
                     /locus_tag="VUR43_000429"
     CDS             36032..36880
                     /gene="dprA"
                     /locus_tag="VUR43_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET5412167.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            37768..38811
                     /locus_tag="VUR43_000430"
     CDS             37768..38811
                     /locus_tag="VUR43_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET5412168.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            38978..41065
                     /gene="topA"
                     /locus_tag="VUR43_000431"
     CDS             38978..41065
                     /gene="topA"
                     /locus_tag="VUR43_000431"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET5412169.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNNEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            41171..41530
                     /locus_tag="VUR43_000432"
     CDS             41171..41530
                     /locus_tag="VUR43_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET5412170.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            41623..42255
                     /locus_tag="VUR43_000433"
     CDS             41623..42255
                     /locus_tag="VUR43_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET5412171.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVDGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            42299..42955
                     /locus_tag="VUR43_000434"
     CDS             42299..42955
                     /locus_tag="VUR43_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET5412172.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            42974..43606
                     /locus_tag="VUR43_000435"
     CDS             42974..43606
                     /locus_tag="VUR43_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET5412173.1"
                     /translation="MNFQLAKYSLLKKFSENIEFTAPEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVTNSLAAVKNGAGRVEGTINGIRERAGNAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGILKNPLTYENI
                     TPELVGVKIPLVKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKK"
     gene            43634..44068
                     /locus_tag="VUR43_000436"
     CDS             43634..44068
                     /locus_tag="VUR43_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HET5412174.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            44080..45117
                     /gene="leuB"
                     /locus_tag="VUR43_000437"
     CDS             44080..45117
                     /gene="leuB"
                     /locus_tag="VUR43_000437"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET5412175.1"
                     /translation="MAKKIVALVGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAAVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKPERISGVDFVVVRELTGEIYFGDHILEERKARDINDYSYEE
                     VEWIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIYGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            45114..45383
                     /locus_tag="VUR43_000438"
     CDS             45114..45383
                     /locus_tag="VUR43_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET5412176.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRTWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            45387..45746
                     /gene="leuD"
                     /locus_tag="VUR43_000439"
     CDS             45387..45746
                     /gene="leuD"
                     /locus_tag="VUR43_000439"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET5412177.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISLVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            45908..46530
                     /locus_tag="VUR43_000440"
                     /pseudo
     CDS             45908..46530
                     /locus_tag="VUR43_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Sua5/YciO/YrdC/YwlC family protein"
     gene            46693..48624
                     /locus_tag="VUR43_000441"
     CDS             46693..48624
                     /locus_tag="VUR43_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET5412178.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     PQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            48611..49927
                     /locus_tag="VUR43_000442"
     CDS             48611..49927
                     /locus_tag="VUR43_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET5412179.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            50102..51088
                     /locus_tag="VUR43_000443"
     CDS             50102..51088
                     /locus_tag="VUR43_000443"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET5412180.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            51152..51223
                     /locus_tag="VUR43_000444"
     tRNA            51152..51223
                     /locus_tag="VUR43_000444"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51185..51187,aa:Arg,seq:ccg)
     gene            51406..52104
                     /locus_tag="VUR43_000445"
     CDS             51406..52104
                     /locus_tag="VUR43_000445"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET5412181.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            52095..55634
                     /gene="smc"
                     /locus_tag="VUR43_000446"
     CDS             52095..55634
                     /gene="smc"
                     /locus_tag="VUR43_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET5412182.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAVLEDKRNS
                     LSQEKSDKESSLVLLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAASAGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARKVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVTDIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            55631..56425
                     /locus_tag="VUR43_000447"
     CDS             55631..56425
                     /locus_tag="VUR43_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5412183.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            56425..57243
                     /locus_tag="VUR43_000448"
     CDS             56425..57243
                     /locus_tag="VUR43_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5412184.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            57247..58524
                     /gene="ftsY"
                     /locus_tag="VUR43_000449"
     CDS             57247..58524
                     /gene="ftsY"
                     /locus_tag="VUR43_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET5412185.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETIE
                     ENNSEVLEPERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(58570..60057)
                     /locus_tag="VUR43_000450"
     CDS             complement(58570..60057)
                     /locus_tag="VUR43_000450"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET5412186.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATANKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(60206..60946)
                     /locus_tag="VUR43_000451"
     CDS             complement(60206..60946)
                     /locus_tag="VUR43_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5412187.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(60946..63111)
                     /locus_tag="VUR43_000452"
     CDS             complement(60946..63111)
                     /locus_tag="VUR43_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET5412188.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            63284..64237
                     /locus_tag="VUR43_000453"
     CDS             63284..64237
                     /locus_tag="VUR43_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5412189.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIVSSIILFLLILYLAYQLKKENERM"
     gene            64314..66302
                     /gene="uvrB"
                     /locus_tag="VUR43_000454"
     CDS             64314..66302
                     /gene="uvrB"
                     /locus_tag="VUR43_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET5412190.1"
                     /translation="MINRITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQTELEEQL
                     AVFDKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            66312..66875
                     /locus_tag="VUR43_000455"
     CDS             66312..66875
                     /locus_tag="VUR43_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412191.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            66841..67329
                     /locus_tag="VUR43_000456"
     CDS             66841..67329
                     /locus_tag="VUR43_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412192.1"
                     /translation="MTVIIKSMETPEEIEGKSFVHWQTWREAYDDLLPTEFQETMTLE
                     RCRLFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALIALDHFSKIFLWVLKDNKRAIAFYQKMGFTFDGQEKMLELGKPIKEKRMVFY
                     SK"
     gene            67402..67869
                     /locus_tag="VUR43_000457"
     CDS             67402..67869
                     /locus_tag="VUR43_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET5412193.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRSPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFYGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(67866..68381)
                     /locus_tag="VUR43_000458"
     CDS             complement(67866..68381)
                     /locus_tag="VUR43_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET5412194.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDKLGYLVKD"
     gene            complement(68393..68920)
                     /locus_tag="VUR43_000459"
     CDS             complement(68393..68920)
                     /locus_tag="VUR43_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412195.1"
                     /translation="MNTRKKTQFMTMTALLTTIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(69202..69765)
                     /locus_tag="VUR43_000460"
     CDS             complement(69202..69765)
                     /locus_tag="VUR43_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5412196.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILSLAIVPRLQTLKK"
     gene            complement(69749..70300)
                     /gene="coaC"
                     /locus_tag="VUR43_000461"
     CDS             complement(69749..70300)
                     /gene="coaC"
                     /locus_tag="VUR43_000461"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET5412197.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLSLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(70312..71001)
                     /gene="coaB"
                     /locus_tag="VUR43_000462"
     CDS             complement(70312..71001)
                     /gene="coaB"
                     /locus_tag="VUR43_000462"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET5412198.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPESHPNLSIREITNTKDLLIEMQERVQDYQILIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            71231..72901
                     /locus_tag="VUR43_000463"
     CDS             71231..72901
                     /locus_tag="VUR43_000463"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET5412199.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKLR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            73229..74404
                     /gene="mutY"
                     /locus_tag="VUR43_000464"
     CDS             73229..74404
                     /gene="mutY"
                     /locus_tag="VUR43_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET5412200.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISGLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            74459..75163
                     /locus_tag="VUR43_000465"
     CDS             74459..75163
                     /locus_tag="VUR43_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5412201.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            75156..76505
                     /gene="vicK"
                     /locus_tag="VUR43_000466"
     CDS             75156..76505
                     /gene="vicK"
                     /locus_tag="VUR43_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET5412202.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     LLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            76507..77316
                     /locus_tag="VUR43_000467"
     CDS             76507..77316
                     /locus_tag="VUR43_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET5412203.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            77407..77649
                     /locus_tag="VUR43_000468"
     CDS             77407..77649
                     /locus_tag="VUR43_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET5412204.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLEDE"
     gene            77651..77905
                     /locus_tag="VUR43_000469"
     CDS             77651..77905
                     /locus_tag="VUR43_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET5412205.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLKAPRQHGKVL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVAILEVGHRRDIY"
     gene            77952..78728
                     /locus_tag="VUR43_000470"
     CDS             77952..78728
                     /locus_tag="VUR43_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET5412206.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELHRMIKDLVEKIS"
     gene            complement(78984..79970)
                     /locus_tag="VUR43_000471"
     CDS             complement(78984..79970)
                     /locus_tag="VUR43_000471"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET5412207.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            80164..82632
                     /gene="gyrA"
                     /locus_tag="VUR43_000472"
     CDS             80164..82632
                     /gene="gyrA"
                     /locus_tag="VUR43_000472"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET5412208.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            82632..83375
                     /gene="srtA"
                     /locus_tag="VUR43_000473"
     CDS             82632..83375
                     /gene="srtA"
                     /locus_tag="VUR43_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET5412209.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            83618..84415
                     /locus_tag="VUR43_000474"
     CDS             83618..84415
                     /locus_tag="VUR43_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET5412210.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLVYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     GILANIFVNIAILSFVLVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            84563..85822
                     /locus_tag="VUR43_000475"
                     /pseudo
     CDS             84563..85822
                     /locus_tag="VUR43_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            85918..87192
                     /locus_tag="VUR43_000476"
     CDS             85918..87192
                     /locus_tag="VUR43_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET5412211.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            87202..88080
                     /gene="truB"
                     /locus_tag="VUR43_000477"
     CDS             87202..88080
                     /gene="truB"
                     /locus_tag="VUR43_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET5412212.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            88321..88623
                     /locus_tag="VUR43_000478"
     CDS             88321..88623
                     /locus_tag="VUR43_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET5412213.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            88731..89369
                     /gene="udk"
                     /locus_tag="VUR43_000479"
     CDS             88731..89369
                     /gene="udk"
                     /locus_tag="VUR43_000479"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET5412214.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            89497..90837
                     /locus_tag="VUR43_000480"
     CDS             89497..90837
                     /locus_tag="VUR43_000480"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET5412215.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLRDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQWDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEVKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            90815..91027
                     /locus_tag="VUR43_000481"
     CDS             90815..91027
                     /locus_tag="VUR43_000481"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET5412216.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            91024..91899
                     /locus_tag="VUR43_000482"
     CDS             91024..91899
                     /locus_tag="VUR43_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET5412217.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQIPFE
                     TESIVSVVESLRING"
     gene            91892..92707
                     /locus_tag="VUR43_000483"
     CDS             91892..92707
                     /locus_tag="VUR43_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET5412218.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            92700..93131
                     /locus_tag="VUR43_000484"
     CDS             92700..93131
                     /locus_tag="VUR43_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET5412219.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIDTFADKIFSCLTDDSSILVIARSGSLVEEIFEQVKNW"
     gene            93138..94805
                     /gene="recN"
                     /locus_tag="VUR43_000485"
     CDS             93138..94805
                     /gene="recN"
                     /locus_tag="VUR43_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET5412220.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            94807..95535
                     /locus_tag="VUR43_000486"
     CDS             94807..95535
                     /locus_tag="VUR43_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET5412221.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDYPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            95614..97437
                     /gene="lepA"
                     /locus_tag="VUR43_000487"
     CDS             95614..97437
                     /gene="lepA"
                     /locus_tag="VUR43_000487"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET5412222.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
BASE COUNT        29678 a        17432 c        21531 g        28917 t
ORIGIN      
        1 tttggattac gaatgaattt gagtgctggt attatcaatc atgaactagg attctagttt
       61 tgcaggaagt ctattatcaa aaataccatc aggattatat aagattgata caggaaaagt
      121 tttatttgat ggtgtaaata ttaatcaaat agataaaaaa atattaagtc aaaatttagg
      181 agtagttcca caggattcgt ttttattgaa cagaagtatt cttgataaca taactttaaa
      241 gcacgaagtt acttcacaaa agatagagga agtttgtaaa gcagttcaaa tctatgatga
      301 aatcatggct atgccgatga aatttaatac tatcatctca gagatgggtt caaatatttc
      361 aggtggtcaa agacaacgga tagcactggc acgtgcatta ataaataatc ctagtattgt
      421 aattttagat gaagcaacta gtgctttaga cactattaat gaggaaagaa taacaaagta
      481 tataaaaagt cagggctgta ctcaaataat tgtagctcat agattgtcaa cgattaagga
      541 tgcggatatt attgttgtaa tgaaaggtgg taagattgtt gagtcaggaa atcataagta
      601 cttaatggat cttggtggag agtactacag cttatataca aaaaggaaat gaggtgtaaa
      661 gaaaatgaag aaagaaaatg aatatgtaat tttaacaaca gcctcactag gggtgatgat
      721 tggaatagtg tttgcaattt ttttagattt tccagttgaa tatggtattt ctttaggctt
      781 attgaatgga atagtattgg gttcgctgat tgtttacaaa aacaataaga attaagcata
      841 attttttgct gtaaactaag gagtagagat ggctatagtt gaaattataa atctaacaaa
      901 aagctttaaa gatattgaag ttattcataa cacttaaata atagagcaac tacagtagta
      961 gcttaaaaac atgattaaat cgctattctt aggagtagcg gtttttcttt ttgtttaata
     1021 ctctttgaaa atctcttcaa accacgtcag ctttgccttg ccgtactcaa gtacagcctg
     1081 cgactcgctt cctagtttgc tttttgattt tcattgagta taaaaagggt taagtaagta
     1141 tagtaaattg aaataagata tgaacaaatc gattagaaaa gtcaaattaa tttctagaaa
     1201 tatgttagaa attggtttga attccgcaat caatttgttc agtttttatt tcatttaatt
     1261 agaatttccc aactgtctaa ctcaactaaa aatccccaat cgtagtgatt gaggattgag
     1321 taaataaatc ttaaacaata ccttgtgcaa tcatggcatt tgctacattt tcaaaggcag
     1381 caatgttagc tcctgcaagg tagtctttat caagaccgta tgtttctgaa gttgttttag
     1441 ctgtgttgaa gatgtttgtc atgatgtctt tgagacggtc atcaacttct tcacgagtcc
     1501 atgagaggcg aagactgttt tggctcattt caagagctga aacggctaca ccaccagcgt
     1561 tggcagcttt tgcaggtccg tataagatac cattttcttt gtaaattttg atggcatcaa
     1621 ggtcgctcgg catgttggca ccttcagata cacagataac gccttgagca accaaacgtt
     1681 tagctgcttc accgttgatt tcgttttgag tggcacatgg aagagcaatg tcatagtttc
     1741 cagcgtaagt ccatacagta ccttcgtggt aggttgcagt tgctttttca gctgcatact
     1801 cagtcaaacg agcacgacgt ttttctttaa catcaaccaa aagatcgaag tcgataccat
     1861 tttcatcgat gacataacca tttgagtcag aaacagaaat aacagttgca ccgagttcag
     1921 ttgctttttg aagagcatat tgagcaacgt taccagaacc tgaaataacg actttcttac
     1981 cagcaaagct gttaccgtta gctttgagca tttcttcagt atagtaaacc aaaccgtaac
     2041 cagttgcttc tggacgaatc aagctaccac caaatccaag aggtttacca gtcaagacac
     2101 cagcatcaaa ttggttaaga cgtttgtatt gaccgtaaag gtaaccaatc tcacgtccac
     2161 caacaccgat atcaccagca ggtacgtcaa gtgatggtcc gatgtgtttt tgcaattcag
     2221 tcatgaagct ttggcagaag cgcatcactt cagcatctgt tttaccttta ggatcgaagt
     2281 ctgatccacc tttacctcca ccgataggaa gtccagttaa gacattttta aagatttgtt
     2341 caaatccgag gaatttcaag atcccttggt ttacagttgg gtggaaacga agtccacctt
     2401 tgtatggtcc aacagctgag ttgaattgaa cacggtaacc acggtttact tgaatttttc
     2461 catcacggtc aacccaagga acacggaaag aaaccacgcg ctcaggctca gtaatacgtg
     2521 ccaagatatt ttcttcgata tactcagggt gtttttcaaa tacaggttcc aaagtgttga
     2581 aaaattcttc aacagcttgg aggaattcag cctcgtgccc gttacgagtt tttacagttt
     2641 cgaacacgct ttggatatat tctttagcag atgtcatatc gttctccttt tattgtcata
     2701 ttttattaca taagacatta tagcagaatt ttttttcact gtaaagaaaa aacagaaatt
     2761 ttctaaaaat tctttcaatt cagtttttgg gttttttgaa aatagataaa aaaacgaacg
     2821 tttttcttgg aaatatcttt ctcaaagaca aaatcttaaa gtatggtatg ctataagaaa
     2881 agaaaatgtt tagcaattca gaaatcactt gttaatttat ccgtgatatg ttagatttgc
     2941 cagtaaaact atgaccattt tggaggaaag caatatttat actagactaa aataaaaaag
     3001 tatatataat agtaatatga aatcaactaa agaagaaatc caaaccatca aaacactttt
     3061 aaaagactct cgtacagcta aatatcataa acgccttcaa atcgttctat agtaaaatga
     3121 aacaagaaca ggacaaatcg atttctaata atattttaga agtagaggtg tactattcta
     3181 gtttcaattt attatatttc gtctgatggg caaatcttat aaagagatta tagaactttt
     3241 agactgtaat caaacaacga tttagcgaaa tgtaaaaaaa tatgaggagt tcgaactcga
     3301 ctctctcctt caagaaacac gtagtggtcg taaccatgca tatatgacag ttgaggaaga
     3361 gaaagccttt cttgcccgtc atttgaaggc tgcagagtca ggagaatttg ttacaattga
     3421 tgccttattt caggcttata aaaaggagtt aggtcgttcc tacacacgtg acgccttcta
     3481 tcaactgttg aagcgccatg gttggcgaaa tattatgcca cgtccagaac atcctaagaa
     3541 agcagacgct caaaccattg tcgcgtctaa aaataaaatc tcaattcaag aagacaagaa
     3601 agcgctttaa aatcagtaga ccttttcata aggttcgctt gatgtaccaa atagtacgcc
     3661 catgcaaaag aatatctatt ttgttgtctt ggacctgcat acgacggata gagataaaat
     3721 tatccagcta ttcaaggatt ggacggatga cagttgggct caatcctcat cgtttgacgc
     3781 tgacttttgg tgtatctgca agtttcttga aaaggatgaa cttggaaaac aagcgccctc
     3841 gactgttcag ggatttacct ctatttccta aggagcaatt acgtgaaaaa tatactggtg
     3901 gagatattgt gattcatgct tgtgcagatg atgagcaaat tgcctttcac gctattcgca
     3961 atctcatccg taaggggaga aatgcggtgc cccctttggt aagaaaaatg agtttgatga
     4021 agtggatttg agtctcttac ctgatgattc gcatgtttgt ttggccaaag aagtggataa
     4081 gccactttta cgtcgttctt attcttactc agatggcatt gatgaaaaga ctggtcagtt
     4141 tgatacgggt ttgctcttca tttctttcca gaaggatcct gataactttg ttaaggttca
     4201 aactaaccta ggtgctactg ataagatgaa tgaatacatc actcacatag gtagtggact
     4261 ttttacttgc tttggtggtg tggagaaagg aggctacatt ggtcagaaat tattggaagg
     4321 ctaaaagctg gttgcttgtt ttagctttgt catttttaat tcttaattct taattcttaa
     4381 ttctttcccc agcaggtgcc caagaaagct tgagttctta tttcgtaaaa atcacagatg
     4441 catccaaagc ggttaaaaat ggtgatcagg ctgaggtcca gaaactcgtt acgaagatgg
     4501 catcagactt cgaaagagta gaaaataagg attctgaggt tggtaagatt gttaaggaaa
     4561 agttagctct atctggagat attactgaag ccaaactcac cgaaatttcc tcagctctat
     4621 tagcttttga aaaagaacaa aatcctgttg acctagatgc ggaaaaggaa aaattggtaa
     4681 accgtctaag tcctcgtttt gaaaccttag agcaggccat tgcctccaaa gatttggaaa
     4741 aagtccgaga agcttttaag aaaatgaatt ccacttggac catcaatgaa agtgtggttc
     4801 gtgacaatag tacagctcat tatggacgtg ttgaaacagc tatttccttc ctgcctagta
     4861 gcatggaaac cgaacctaca gatgagtctg gaacatgaaa acagcagttg atttcaagaa
     4921 acaaaaaaga acagccgaaa ctgttctctt atcattattt gagaccgtat tttttgttga
     4981 aacgatccac gcgtccatct gcttgagtga acttttgacg tccagtgtag aatgggtgtg
     5041 agtctgatga aatttccaca cggatcaatg ggtaagtttc gccttcgaac tcaactgttt
     5101 cgttagagcg ttttgttgaa ccgctaagga attggtaacc agtagttgtg tccatgaaga
     5161 caactgggcg atattctgga tggatatctt ttttcatttt gcaatatttc ctttctgcca
     5221 tggtctcttt gcgagccata gattgttacc atactagtct atcagattct gaaaagtttg
     5281 gcaagtattt tatcagtttt taagcaagtt ttttaacttt tggtagatga tttcgttttc
     5341 ttctaggcta taggaattag caccacttgc tagagggtgg cctccaccat catgctcctt
     5401 ggcaatttca ttgataggat ggactttact gcgtaagcga actcggtagt ggccatcagc
     5461 ctgttcgaca aaaattcccc agagactcac tctgtcaatg cgtccaggtg caccgacaat
     5521 ggctgcagtt tcagcatcgg ttacattgta ttgtttcaag acttcttgac tcaggataac
     5581 gcgagcagca ccattttcat ccacttccag atggtcgtag atgtagcctt gcagtttagc
     5641 aattttgtag ctcatagtgt ccattttgcg agtgagagcc gcaaagtcaa agttatgttc
     5701 tctcaaataa gcagccagac gaagagtccg tgcagtggta gaagggtaga ggaagcgacc
     5761 tgtatcaccg acaattcctg caaagagcaa ctcagcatcg cgatctgcca aggctagttg
     5821 ggttgtttgg gcaaataggg taatcatctc gctagcgcta cttgaactag tatcgaccca
     5881 agacaggtca ccgtatacat catcatttgg atggtggtca atcttaatga gaaaatcacc
     5941 ttgactatag cgcttatcat cgatacgagc agtattagct gtatcacaga cgatgacaag
     6001 tgcgccttgg taggctctat cttcaacaag atccatctca gccatccaag taagagttgg
     6061 ttcatcaaaa ccgacggctt tgatggtttt ttctgggaaa tgatgttcca gcaaggcttt
     6121 caatcccacc tgacttccca aggcatcagg gtctggtttc atatgacgat gaatgataat
     6181 ggtgtcgtat tctttaattt tttctaaaat ttgttggcaa atctccataa ataacctcaa
     6241 ttctttctca tttcattgta gcacaagaat ttttattttt aaaatgaaaa agatgtgata
     6301 taatggagaa agataaattg aggaggacga tatggcatta gcaaaaattg tatttgccag
     6361 tatgaccggt aataccgaag aaattgcaga tattgtagca gacaaattac gtgacttggg
     6421 cttggatgtt gatgttgatg aatgtacaac tgttgacgct tcagacttct tggaagcaga
     6481 catcgctatc gttgcgacct atacttatgg tgatggtgaa ttgccagatg agatgatgga
     6541 cttctacgaa gacctagcag atctcaactt gaatggcaaa atctacggag tggtcggctc
     6601 aggagatacc ttctacgatg aattctgtaa ggctgttgat gactttgacc gtgtctttgt
     6661 gtcaacagga gcagaaaaag gttcagagtg tgttaaagtt gatctttctg ccgaggaaga
     6721 agatattgaa cgcttggaac aattcgcaga agaattggtt gctaaagtag gataagcata
     6781 aaagtgcgct gatgtaatca atcagtgcat ttttcttatc gagagttggg attttactag
     6841 cctaattgat ggctttttga tacaataatt caaataaagg aggagactgt atggatttag
     6901 atattattcg tcaagaaatc gatcaaatcg acgaccaaat tgtcaaactg ttagaagaac
     6961 gaatgcactt agttgaagga gttgtcgctt ataagaaggc ttcagggaaa ccgattttag
     7021 atactaagag agaagcagtt atttttgaaa aggttagaag tcgtgtagag gacaagcgct
     7081 atcaggagac tattgtcgcg actttttcgg acatactcaa acgttcgcgt gattatcagg
     7141 atcaaaatat caaatgaaaa aagaacaatt ttatccgcta gggatttttc tagctgctat
     7201 gttgggcgga cttgtccgct acctagtttc cacttggtta ccagccagtc cagatttccc
     7261 ttggggcact ctctttgtca actatctggg aattttctgc ttgatttatc ttgtcaaggg
     7321 ctatctggtc tataagggga ctagtaaggg cttgatttta gcactgggga cgggtttttg
     7381 cggaggttta acaacttttt ccagcctaat gcttgatact gtgaagctgc ttgatacagg
     7441 gcgttatctt agtttgatac tgtatttgct tttgagtatc ggtggaggcc tgcttttagc
     7501 ttactatttg gggaggaaga aatggtaatc gtctatcttg caatcgcctg tggcttggga
     7561 gcactcgtac ggtatttctt ttctcgctat aatcaagctt ctaaattgcc actcggaacg
     7621 ctcatagcta atcttttagg ttgtttttta attggagtat tctacaatca tgtagagtct
     7681 aaggaagtat atgctattct agcaacagga ttttgtggcg gtttaacaac tttttcgacc
     7741 ttgaatgacg aacttcaaag actgctaagt gataagaagg tcttttattc ttacctgact
     7801 ttgacttaca taggtggttt ggttgcgatt tttttaggaa ttttgctata aatttcttta
     7861 ctttttttta gaaatttggt aaactatatc ttgtgtgtaa tggacgcaca aaaatacagt
     7921 ttatccgctg aggaagattc ctcaagattg acaaagatag gagaataaaa tgaatccatt
     7981 aatccaaagc ttgactgaag gtcaacttcg tacagatatc ccatcattcc gtcctggtga
     8041 cactgttcgt gtacatgcga aagttgtcga aggtaaccgt gaacgtatcc agatttttga
     8101 aggtgttgtt attgcacgta aaggtgctgg catctctgaa aactacacag ttcgtaaaat
     8161 ctctaacggt gtaggtgttg agcgtatctt cccaatccac actccacgtg ttgaaaaaat
     8221 cgaagttgta cgttacggta aagtacgtcg tgcgaaattg tactacttgc gtgctcttca
     8281 aggtaaggca gctcgtatca aagaaatccg tcgttaattc gactaaaaaa ctctgctttt
     8341 cagcagagtt tttatctagc tcccttagtt caatggatat aacaactccc tcctaaggag
     8401 tagttgcagg ttcgattcct gcagggggca tgtaattaga tatcaaagaa gtttgtcaaa
     8461 aagtctttga tattaaaaga acgcataata taggggattg tctccataat attatgcgtt
     8521 ttattattga aaaatttggg caatcatcag ataaaattga gactatatcg agtatataaa
     8581 tgtttgtata gtcaatttat tcaaaatcgt caagttctaa attatttaaa ggactataac
     8641 attcatattt ctttaagtaa ttgtttattt cttcagcagt ggaacgaggt aaattaactc
     8701 ttaaatagtc aatatcttcc ttagataaaa aatgatttgc attcaaaatt gagaagcgaa
     8761 ataatgcttc atcaaaagca aaatcataat cgtcatcaga taatgattcc attaatgttt
     8821 gaatatgttt tagtgagtag tcaggtatcg aatcgggata atatactgga taatcagtgg
     8881 ctgaaaaatt gttttctaat cctgaaatag taattatcaa agattctatg taatatatta
     8941 aagcatgttt aatattacct tcttgttcca aatgtcttcc ctgagccttt cgtgtgttag
     9001 ataagcatcc aaaatctcct gatacagtat tcctatgagc ttgtttattt aagagactcc
     9061 attttatatc accaaaagtt gctttaaaag agatattgtt tttttcttta caataatctt
     9121 ccatagttat gtctttatca tagtatgctt tgatatagtc actatgttcg ataataagat
     9181 tttgtgcttc ttttgttagt ttaaattcga acggaatatc taaattgtca atgttaacat
     9241 tattaattat tcttgtaatt aattctgctt tttttccaga agtagctaaa ttatgtttag
     9301 ataatatagt ttttaattct actactgtaa gatatgataa agtcttattt ttagtgaagt
     9361 atcctaattt gtataattga ttgtgtgtag attcagggtc aatttgaaga gagtatttaa
     9421 aatatcttgg gaaattataa tttctccctg ttttttgagt ccaatctatg agtatgagtt
     9481 gcccaggagt aaggccacat tctaattcgt ttaggtaaaa attgttacaa tcagaatttg
     9541 tgtctctatt atgattattt tgttttaaat taaatagttt gctaaaaaaa ttcattggat
     9601 tttattgcta atcaattctt attgaaaaat gatactttta cagtacccat gttcggatgg
     9661 cgtgggcaac gccggattcg tcatttgttt tagtgatgta tttggcgatt tttttgattt
     9721 ctggatttcc attttccatg acaacggggt ttccaacgac ttccagcatg gcacggtcat
     9781 tttcttcgtc accgattgcc atggtttcat ctttggtcaa tcctagtttt tcagctaagt
     9841 gagtaatagc tgaacccttg tctacattct ttttaaggag ttcgaggtag aaaggagcag
     9901 atttgttgat agagtagtgc tcgtaaaatt cggctggtat tttttcaatc gcagcatcga
     9961 ggatttctgg ttcatcgatg aacatacact tgacaatttc cttgccagcc atttcttcag
    10021 gggtacggta gaagataggc atgctgacga gggttgattc gtgtacagtg tattttccga
    10081 tattgcgatt tgcagtatag ataccgtcct tggtaatggc atgcatgtgg acaccgagct
    10141 tgcgactgag gaattccata tccagataat cctcataggt caaggattcg ctgataatct
    10201 catggccagt agcagtttct tggacaaggg caccattgaa ggtcaccaca tagtcacctt
    10261 ggtctctcaa ctgcaagtcg tccagaagtt tggcaacacc tgcgatgggg cggccagttg
    10321 caatcacgac tttgacacca gcttctttgg catcttggat ggcagaaaag acttcaggag
    10381 tgatttcctt ttggctgttg actagggttc cgtcaatatc gacggcgatt agtttaatac
    10441 tcataaattt cctcttttag tttttatttg gggtaaaatg atcgttctca atcaagtgta
    10501 aaaattgctg ggtgatgctt gcgaagatgc tgttttggtc taacatttct ttcgggaaat
    10561 aaaagcgatt atctccgtgg cgacttccag caagggattg gacgataggg gacaggctag
    10621 agagttctgc cagttctcca tttttttgta aaatctcaat ctgtgtccgt gggttttcag
    10681 attcgggacg atagatatca taagggaggt caaagttctt atgaatggca gtgtagtagt
    10741 cgggatcaaa gccgatatcc tcagctaatt ttctcatgct ggcgagttgg tcttgatcct
    10801 cttgcgaaaa gctaatggat ttaaagacct tgcggttgac aaagcgttgc gataaatctg
    10861 caagaatctt gtcaggactg gtcatccaaa gctggaagta ggtattcatc acgccatcat
    10921 ccagagccag atagtcagtc aaggtcacat ttttttcgaa gaaaggcagg aggtgtggag
    10981 aagttcgggc aaagaaatcc ttgtcctcag gatagagttc cttggcgcgt ttgagaagat
    11041 tctgtaggag aacttccatg gcgcgtgttg cggggtggaa ataaacctgc atgtacatct
    11101 ggtagcgact gaggacgtag tcttcgatgg cgtgcatgcc attgcgctga aaggcgatac
    11161 cattttcgat aggacgaatg actcggagga ttcgagtcag gtcaaattcc ccataggatg
    11221 ctcctgtaaa ataggagtcg cgcaagagat agtccatgcg atctgcgtca atctgactag
    11281 aaatgagctg cacgacctgc ttattaggat aggtatggtc aatgacactg gccacctttt
    11341 ctgggaaatc aggtgccact tgtagcagga cttggtgaat ctctgtctca ggattttgaa
    11401 taatctcctg agtaatggct tcatggtctg tatcaaagag attttcaaaa gtatgggagt
    11461 aggcaccatg cccaaggtcg tgtaggagag cagcggtcat ggtcaagaga gactcggcag
    11521 gattccattc ctcaggatat ttttcttcga aaatctctgt gatgcgtcgt gcaatttcat
    11581 agactcctag acagtgagag aagcgactgt gttctccacc gtggaaggta taactggaag
    11641 ttcccagttg tttgatccgg cgcaaacgct gaaattcttt tgtattaatc aagtcataga
    11701 tgatttgatt attgacatgg atgtagttgt gaacagggtc acggaatact ttttcgttca
    11761 tatgaccatt atagcaaaat cctgctcttt ttggtaaaat agtaggacaa gagacaagaa
    11821 agagggcctg atgtgaagat tcggatgcga aatacaattc agtttgatga gcagttggaa
    11881 gtgattgacc agctttatga tgtggaagtg catgaaaaag gagattatag ctacctgctt
    11941 ttctataatg aggaaaagga aaaagtagtg attaaatttc atggtcaaga acttgtgatg
    12001 agtcgatttt ccaatcccaa gaccattatg cgctttctaa aggatagtga tagtttagcc
    12061 tatattccca cacctatggg tatgcaggag tttaccatcc aaacgagcca ttatcaagtt
    12121 gataggcaaa agattgaact agattatcaa ctacaaaatc aagagggaca tccctttgcc
    12181 agctatcaat tggaaattac ttggggctag gctcatgtct ttttcaaatt tagctatcta
    12241 tcttcttgga tcggcttcct agtgtggtag attaggctaa tttttggtat aataaaagtt
    12301 atggaaatcg aaaaaaccaa tcgtatgaat gcgctctttg aattttatgc ggcgcttttg
    12361 acagataagc aaatgaatta tatcgagctc tactacgctg atgattacag ccttgctgaa
    12421 attgccgagg agttcggtgt cagtcgtcag gctgtctatg acaatatcaa gcgaacagaa
    12481 aagattctgg aagattatga gatgaaattg cacatgtact cggactatat tgtccgcagt
    12541 cagatttttg atcagatttt ggagcgctat cccaaggata actttctgca ggagcagata
    12601 gaaattttaa caagcattga taatagagaa taagaggaag aaaaatggca tttgaaagtt
    12661 taacagaacg tttgcagaac gtctttaaaa atctacgcaa aaaaggaaaa atctctgaat
    12721 ctgatgtcca agaggcaacc aaagaaattc gcttggcctt gctcgaggcc gacgttgcct
    12781 tgcctgttgt aaaggacttt atcaagaaag ttcgtgagcg tgcagtcggg catgaggtca
    12841 ttgatacact taatcctgcg caacagatta ttaaaatcgt tgatgaggaa ctgacagccg
    12901 ttttaggttc tgatacggca gaaattatca agtcacctaa gattccaacc atcatcatga
    12961 tggttggttt acaaggggct ggtaaaacaa cctttgctgg taaattggcc aacaaactca
    13021 agaaagaaga aaatgctcgt cctttgatga ttgcggcgga tatttatcgt ccagctgcca
    13081 ttgaccagct taagaccttg ggacaacaga ttgatgtgcc tgtctttgca cttggaacag
    13141 aagtaccagc tgttgagatt gtacgtcaag gtttggagca agcccaaact aatcataacg
    13201 actatgtctt gattgatact gcgggtcgtt tgcagattga tgagctcctc atgaatgagc
    13261 ttcgtgatgt gaaagcattg gctcaaccaa atgaaatctt gcttgtcgtt gatgctatga
    13321 ttggtcagga agcagccaat gttgcgcgtg agtttaatgc tcagttggaa gtgactgggg
    13381 tcatccttac caagattgat ggcgatactc gtggtggtgc tgctctgtct gttcgtcaca
    13441 ttactggaaa accaatcaag ttcactggta caggtgaaaa gattacggac attgaaacct
    13501 tccacccaga ccgcatgtct agccgtatcc ttggtatggg ggatatgctc actttgattg
    13561 agaaagcttc tcaggaatac gatgaacaaa aagcccttga aatggctgag aagatgcgcg
    13621 aaaacacctt tgattttaat gatttcatcg atcaattaga tcaggtgcaa aatatggggc
    13681 cgatggaaga cttgctcaag atgattccag gtatggccaa caatccagcc cttcaaaaca
    13741 tgaaggtgga tgaacgccag attgctcgta aacgtgccat tgtgtcttcg atgacacctg
    13801 aagagcgtga aaacccagat ttgttaaatc caagccgtcg ccgtcgtatt gctgctggtt
    13861 ctggaaatac attcgtcgaa gtcaataaat tcatcaagga ctttaaccag gctaaacagc
    13921 tcatgcaggg tgttatgtct ggggatatga ataaaatgat gaagcaaatg gggattaatc
    13981 caaataacct tcctaaaaat atgccaaata tgggaggaat ggatatgtct gcccttgaag
    14041 gaatgatggg acaaggcggt atgcctgact tatcagctct cggaggagca ggaatgccag
    14101 atatgagcca gatgtttggt ggcggtttga aaggtaaaat tggtgaattt gccatgaaac
    14161 agtccatgaa acgtatggct aacaaaatga agaaagcgaa gaagaaacgc aagtaagaca
    14221 agagattgat gcaaatctca tttgatgaga aaataaagta aaaatttcta tgataaaacg
    14281 tacagtatca aggttttaga atatctgata ttatacgttt tttgatttta ataattttgt
    14341 taagacactt ttattatggt atgcgaaaaa tccactcagc tgtctgagtg gattaggtgt
    14401 atttagactc ttagtcttta ttttcgtatg gcaagatcaa gttcaagatg attcctgtca
    14461 tggctgaaag ggcagtacct gaaagtgtaa ctggaccaag tttaaggata gctcctccaa
    14521 gtccaagaac caacatagca cttgcgatga tgaggtttcg catttgagcg aaatcaacac
    14581 gttctttaat caagactttc aaaccattgc tggcgataac cccatagaga aggattgaca
    14641 taccaccaag tacagcgttt ggaatagttg aaatcaaggc agtgaattta ccaaggaagc
    14701 tgagggcaat cgcgatgaag gcagcgttac ggataactga gacagaagcg atacgagtca
    14761 taccgataac ccctgtattt tctccgtaag ttgtattggc tggtccacca aggaaggcag
    14821 aaacagaagt tgcgataccg tcaccaagaa gagtacggtg aagacctggt tcttttaaga
    14881 attgacgacc acagatttga cccaaaacag tatggtctcc gatatgttca gaaattgtta
    14941 cgatagcgat tggcaagata gcgatggctt ctggaccaaa gtaaagattg tactctttaa
    15001 aggcaccacc tgtgctaaat ggcaagtaga aaccaggaat ttcgaaccag ttggctttaa
    15061 gaactggtgt aaagtcaacc aagccaagag ttagtgcgaa aaggtaacca ccgataatgg
    15121 caaagaggaa tggaatgatt cgtaggaagc cttttccttt tgtattgata aaggcagcaa
    15181 ttaggaaagt aacaacggct accagagcat ttttccaatt tccgtctgct acaagacctg
    15241 cattggtaac agctgaacct gcaagtccaa gaccgataac gatgatcata ggaccgataa
    15301 tgattggtgg caagagttta tcaatccatt ttgttcctac aaatcggatg ctggtagcaa
    15361 caaggacata gaccaaacca gtcaagataa cccctgtttg ggcagcagat acatcccccc
    15421 ccatttcttt catagccagt gacatagctg tgataaaggc aaatgaagaa cctagataaa
    15481 ctggaacttt aaaaccagta gcaatcatgt agatgagtgt tccaacacct gaagcaaaaa
    15541 gggcaacaga tacaggcatt cccaaaatca atggtaccaa gatggtcgca ccaaacatgg
    15601 cgaaaacgtg ttggaaacta aggagaattc cttttccatc cgaaggacgt tggtcaacgt
    15661 ctagtaacaa atcaacagtt gattcttgtt tcatataaac ctcacttttg ggcatcagaa
    15721 aagagcccat tattttacag caataggccc tcagagtaag acttctctaa aatctagact
    15781 ttaaagagtt tcaaatattt ctgcgtcttc gtcacctcac gggatgacat taaaaacctt
    15841 tgcttaggat agtatagcag aaaaaaatga ttttgtaaat cattttttcc cgagcctaga
    15901 aataaaagag cgaggctgat tttgtaaaca tttgtttact aaaaaattta aagtgggcgt
    15961 ttatttggca taccagcctt acgtggatat ttatttggtg tttctttttt cttttctacc
    16021 actgtgatat agcgcggatc tctattcggt agggcgtagc tgagattgtc ttcgacctta
    16081 ctaaaaagga gattgagggc attcttagct tctaataatt cctcaggcgc attgctagcc
    16141 ttgagtgcta atagtttgcc accaacctta aggtagggaa tagtcaattc agataggacc
    16201 tgcatacggg caaccgcacg agctgttaca aaatcatatt gagcacggaa gttcttgtct
    16261 tgggcaaaat cttcggcacg tccgtggtag aaatgaactc cgttcaaatc cagttcttga
    16321 gccaagagtt gtaggaagtt gatgcgctta ttgagtgaat caataatggt cacatctaac
    16381 tccggataga gaattttcat tggtagacta ggaaatcctg ccccagcccc gatatcaaga
    16441 agtttgatag tttcattggg aatcaaacct tgaagaatgg gtgcaatcga atcgtaaaaa
    16501 tgtttgagat aaacttcttc cttgtccgta atcgccgtca aattaatctt ctcattccac
    16561 tcgaccaaga gctcaaaata acgttcaaat tgttcttttt gctggtccga aagtggaaga
    16621 ttctgctcgg caagcaagtt gtaaaatgtt tttggtttca tagttatttc cttctttagt
    16681 atcatcttat tttaccacaa tcatagaaaa tttgatatac tggtactaat ctaaaagcag
    16741 aaaggactta tattatgact tggattattc ttggagtttt agctcttgtt gttatttttg
    16801 tgattgttag ctataacggt ttggttaaaa atcgtatgca aaccaaggag gcttggagtc
    16861 agattgatgt tcagttgaaa cgtcgcaatg atctcttgcc aaacttgatt gagactgtaa
    16921 aaggttatgc caaatatgaa ggttctaccc ttgaaaaggt ggcagaacta cgtaaccaag
    16981 tggcggcagc gacttcacca gcagaagcta tgaaagccag tgatgccctc actcgtcagg
    17041 tttcaggtat ttttgcagtt gcagaaagct atccagattt gaaagctagt gctaactttg
    17101 ttaaattgca agaggagttg acaaacacag aaaataaaat ttcttactct cgtcaactct
    17161 ataacagtgt tgtcagcaac tacaatgtaa aattagaaac tttcccgagc aatattatcg
    17221 ctggaatgtt tggatttaaa gcggcagatt tccttcaaac acctgaagag gaaaagtcgg
    17281 ttcctaaagt tgattttagc ggtttaggtg actaagatgt tgtttgatca aattgcaagc
    17341 aataaacgaa aaacctggat tttgttgctg gtatttttcc tactcttagc tcttgttggt
    17401 tatgcggttg gttatctctt tataagatct ggacttggtg gtttggttat cgcactgatt
    17461 atcggcttta tctacgcttt gtctatgatt tttcaatcga cagagattgt catgtccatg
    17521 aatggagcgc gtgaggtgga tgagcaaacg gcaccagacc tctaccatgt agtggaagat
    17581 atggctctgg tcgctcagat tcctatgccc cgtattttca ttattgatga tccagcctta
    17641 aatgcctttg cgacaggttc taatcctcaa aatgcggctg ttgctgcgac ttcaggtcta
    17701 ctagctatca tgaatcgtga agaactagag gctgttatgg gacatgaagt cagtcatatt
    17761 cgtaattatg atatccgtat ttcgactatt gcagttgccc ttgctagtgc tatcaccatg
    17821 ctttctagta tggcaggtcg tatgatgtgg tggggtggag caggtcgcag acgaagtgat
    17881 gatgaccgag atggaaatgg tcttgaaatc attatgctag tggtttccct actagctatt
    17941 gtactggcac ctctcgctgc aaccttggtt cagctcgcta tttctcgtca gagggaattt
    18001 ctggcagatg catctagtgt cgagctgact cgcaatcccc agggaatgat taatgcccta
    18061 gataagttgg acaatagcaa acctatgagt cgccacgtcg atgatgctag cagtgctctt
    18121 tatatcaatg atcccaagaa aggtgggggg ttccaaaaac tcttttatac ccacccacct
    18181 atctcagaac ggattgaacg tttaaaacag atgtaaaaga atccagaggt cgtctctgga
    18241 tttttgctat gttgcaaatt tatacatctt ctaaattaac taactccaaa ccgtgttctg
    18301 tcaagcggta gatgcttgaa cagacctctt ttaagaaacg acggtcatgc gaaacagtga
    18361 tgagaccgcc tggataggtt gcaaagagtt ttctgatttg gggttgagaa gtgggagaaa
    18421 agtttcgtgt gggttcatcc agcaggagaa agtttggttt gcgcaggact aaatccaaaa
    18481 gcaggagttt tccctgttgt ccgccagata aggagcgaat ttgatgctgc atttctggat
    18541 aactgaaatt gagactagct aggtgagatt ggattttctg tagttcctct ttttccccag
    18601 ttttgctgag gtaggctatt ggtgataaat ccaattgcag ttttttgtgg taatcttgtg
    18661 gcataaaacc aagggaaatc tctcttttat cattcagaag ttgctttaat ttggctaaca
    18721 gagttgattt cccaacacca tttggcccga taataccgat tttttcttgc ccacggacag
    18781 ttagttgtag tttttgaacc aaaactcggt cgtcaatgga caaattttct ttttccagtt
    18841 ggactaagac tttagaagct ggtaatggtt ggatgtctga aaagaaaagt tggatttgtt
    18901 cctcttcaag tggcttttga gtcatggact gagctgcctt ttcgtagcgt ttttcttgtg
    18961 agaggacagt tttcatcttt ttagccaata ggcgaccggc agtactgtct ttggtagctc
    19021 gaagcgcagt ttctacattt tgtttgactc tccgatgttt ttccatggtt ttatcgtagg
    19081 ctctttggtt gttagcagct tgctgacttt gtttggcaaa attagccttt ctctgctcac
    19141 tatagctttc atagtctaaa tgctctacta gcgtttccgc ttctttacgg tgtttgacca
    19201 gtcgcaagtg aacaatagtg tctgccgttt cagaaagaaa gtcttcatca tgggaaatga
    19261 aaataacggt ttgcctggtc ttttgaatct ggccttttag ccaatcaact gtctcaaggt
    19321 ctaggtcatt tgaaggttca tctaaaaata gaatctcaaa gggtttggct aactcatgga
    19381 taagctgaat tttcaaagct tctccccctg atagattgcc aatcttttgg tcacttgcga
    19441 aacgattgct atcaaaatgc aattcctccg ccaaacgata gaggatactg tagtctaaat
    19501 caatagaatc taaaaagaag tagtcgtgta aagttttctt tttcagctcc tcgggaagtt
    19561 tttgaggaat gtaggccagt gactgatagt cagattggat gtttcccttg atagtgaaat
    19621 cagacaaagc ttcccccatt aaaattttaa gtaaggttga tttgccattt ccttcttcac
    19681 caataatagc aaccttttcc ccgtcttgga tggtcatgct taggtcagat acaagatctc
    19741 gtaaatcttt gttttgtgtg atggttagat gattgatttt tatcatatga tttccctttc
    19801 tagaatgttc atagtgcata acaaaaagct ctactttacc tagtagagcc caaagtctat
    19861 gtcaaaaaaa ctctattaac atgccagaaa aagagcataa aagagcacac aaaaagagac
    19921 aaaaacaaga tctactaaat aaaggttctt tatttgatag acttagttgt tcatgtctcc
    19981 cttacctccg agtattagta tctttatatt atacctttaa ggaaattttg tcaacagaaa
    20041 actggaaatt ctatgctcta aaatccaaaa acaggtccat agagacttag tacgtgtttg
    20101 acatgctcgt aatggaattt atcatagttt cgccaagcag tgcgtgcttg atcgtttagt
    20161 tttaggctac ccagtccaat cagaagactg gtgggttggt aaaatttctc aagatcaatt
    20221 aagatactgt tgttcaactt ttccgttttt ttgagctctt gcatagtagt gtttagcagc
    20281 tcttgtagtc gaatatcatc tgccgtaccc tgtttacagt tttgatagct tttatttaac
    20341 ttggatagga gttgaatgag tttcttgtct tccatgtgag catcctcctt gatctgatgt
    20401 actctttccc tatagtatag cactaaaaaa caaaactgtc atagtaaata tgttaaaatt
    20461 ttgaatttta attacaaagt ttggtgtgct gatttgtagc cttttcatgg tataatcaag
    20521 agagtaaatc tttatggagg aagtatgaaa ttaaatattc aagaaattcg taagcagtct
    20581 gaaggtttga actttgaaca aacgttagat ttagttgatg acctgcgtgc acgtaatcaa
    20641 gaaattttag atgtaaaaga tatccttgca gttgggaaag tacaatatga agaccgtatg
    20701 tatttcttag attatcaact atcttatacc attgttcttg cttcgagtcg cagtatggag
    20761 ccagttgagt tagttgaatc ttatccagtc acggaagttt tcatggaagg tgcaactaac
    20821 catctaaatc aagaaatttt agatgatgac ttggtcttgc ccatcgaaaa tgaggcgctt
    20881 gaccttgctg agagtgtatc agacaatatc ctgctaaaca ttcctatcaa ggtcttgacg
    20941 gctgaagaag aagctggtca aggatttatc tcaggaaatg actggcaaat catgacagag
    21001 gaagaatacc aagctcaaaa agcagtaaag aaagaagaaa acagtccttt tgctggctta
    21061 caaggactat ttgacggaga tgaataatgg tcttgtcaaa aaaacgagca cgaaaggtgc
    21121 tagaagaaat cattgccctc ttcccagatg ccaagcctag tcttgatttt accaatcatt
    21181 ttgaactcct ggttgcggtc atgttatcag cccagacgac agatgcagcg gtaaataagg
    21241 ccacaccagg tctctttgtt gcctttccaa caccccaagc tatgtctgta gcgacagaga
    21301 gtgagattgc ttcacatatt tctcgcttgg gattgtatcg gaataaagct aaattcctta
    21361 aaaaatgtgc ccaacagtta ctagacgatt ttgatggtca agtccctcag acacgtgaag
    21421 aattggagag tttggcaggt gttggtcgca agacagccaa tgttgtcatg agtgtaggat
    21481 ttgggattcc agcctttgca gtggatactc atgtggagcg tatttgcaaa caccacgata
    21541 ttgtcaaaaa atcagcgacg ccacttgagg tggaaaagcg ggtcatggat atcttgccgc
    21601 ctgagcagtg gttagctgcc catcaggcca tgatttattt tggaagagcc atttgccatc
    21661 caaaaaatcc agagtgtgac cagtacccac aattatatga ttttagcaat ttgtaagatg
    21721 ctacattgaa actttttgct tgattttaag catgctttgt gctatagtaa atgataacta
    21781 aatattcctt taaacctgtc ccgtgaggca ggcaaggagc gcgataaagt agaagggtga
    21841 agtctatact gtgtgcagta gggctcgctt ggctataaat ttcaagtctc cttgtttaag
    21901 gagacttttc tttttggagg tttgtcatga aaacaaaaga agttgtagac gaattgaccg
    21961 tcaaacgagc gattacgcgt attacttatg agattatcga acgcaacaaa gatttgaata
    22021 agatcgtctt ggctggtatt aaaactcgtg gtgtctttat tgcccaccga atccaagaac
    22081 gtttgaagca gttagaaaat ctttcagttc ctgttgtgga attggatact aaacctttcc
    22141 gtgatgatgt taaaagtgga gaagatactt ctttggtttc tgtcgatgtg acagaccgcg
    22201 aagttatctt ggtggatgat gtgctctata caggtcgtac catccgtgct gctattgata
    22261 atattgtcgg tcatggtcgt cctgcgcgtg tgagtttagc agttctagtc gatcgtggac
    22321 atagagaatt gccaatccgt ccagattacg ttggaaaaaa tatcccaacc agtcgttctg
    22381 aagaaatcat cgtagagatg acagaacttg atgaccaaga cagagttctg attactgaag
    22441 aagcttagaa agttaaagga gtagccatgt cagaaaatca acaagcattg aaccatgtgg
    22501 tgtccatgga agacctcact gtcgatcaag taatgaaatt gatcaagcga ggaattgagt
    22561 ttaaaaatgg agcccagctt ccctatgaag accatccgat tgtttccaat ctcttctttg
    22621 aggattctac acggacacat aagtcctttg aagtcgcaga gattaaactt ggattggaac
    22681 gacttgactt tgatgtgaag actagttcgg ttaataaggg tgagacactt tatgacacca
    22741 ttttgactct gtctgcttta ggagtggatg tctgtgtgat tcgccatcca gaggtcgact
    22801 actatagaga attgattgct agtccaacga ttacgacttc catcatcaat ggtggagatg
    22861 gttcgggcca acaccctagc cagagcttgc ttgatttgat gaccatttat gaggaatttg
    22921 gccactttga gggtcttaaa gttgctattg caggtgactt ggaccactca cgcgttgcca
    22981 aatccaatat gcagattttg aaacgcttgg gatctgaact ctttttcgct ggacctgagg
    23041 aatggagaag tcaagagttt gcagactatg gacagtttgt aaccattgat gaaatcattg
    23101 atcaggttga tgtcatgatg tttctccgtg tgcaacacga acgccatgat agtggagctg
    23161 tattttcaaa agaagactac catgcccaac atggcttgac tcaagaacgt tacgatcgtt
    23221 tgaaagaaac agcaatcctc atgcacccag ctccaatcaa tcgtgatgta gaaatagcag
    23281 accacttggt tgaagcacca aaatcacgga ttgtccaaca aatgaccaat ggtgtctttg
    23341 ttcgaatggc aatcttagaa tccgtactag cgagtagaaa cgccaactaa aacacaagac
    23401 gttaaaagac gccagtgagc gtccacgaga ggtgaaaata tgacaaaaag aattctagta
    23461 ttagaagatg gcacagtttt tgaaggcaag gccttcggag cagatattga tgtaacaggc
    23521 gaaatcgtct ttaatacagg gatgaccggc taccaagaat ccattacaga ccagtcttat
    23581 aatggacaaa tcttgacctt tacttatcct ttggtaggaa attatggtat taatcgtgat
    23641 gattatgaat ccattattcc aacttgtaag ggagtcgttg tttttgaaga agcgcgtaga
    23701 gctagcaact ggcgcaacca aatgaccttg gatgaatttt tgaaagccaa gaaaattcca
    23761 gggatttcag gaattgatac gcgtgctctt accaagatta tccgtaagca tggtactatg
    23821 cgtgcaacct tgacccatgt tggggacagt atggaccatg tgacggacca gctccaagca
    23881 acagttttac cgacagacaa tatcaaacag gtttctacta aaacgtctta tccagctcca
    23941 ggagttggtt tgagcgtggt gctagtggac tttggtctca agcactcaat cctacgtgaa
    24001 ctttctaaac gcaactgtaa cgtgacagtt gttccttatt cgacaacggc tgaagaaatt
    24061 ctccatctca atcctgatgg agttatgttg tcaaatggtc caggtaaccc agaagacgtt
    24121 ccacaagcac tcgacatgat tcgcggtgta caaggaaaaa ttccaatctt tggtatttgt
    24181 atgggacacc aactctttgc aatggcaaac ggggctaaga cctataagat gaagtttggc
    24241 caccgtggat tcaaccatgc ggtacgtgaa atcgcaacag gacgagtaga cttcaccagc
    24301 cagaaccatg gttatgcagt cagccgcgag gatttgccag agcacttgat tattacccac
    24361 gaagaaatca atgacaagtc agtggaaggt gtgcgccaca gataccaacc tgctttctct
    24421 gttcaatacc acccagatgc agctcctggg ccacacgacg ctagctacct atttgacgag
    24481 tttatcgaga tgatggaagt ttttaaacaa tcaaactaag aacgagtaaa agctcgtcgg
    24541 agaatttatg taactgaaca cggacggaaa gctcagaatg tagagaaacc aacttggatt
    24601 gtcaatcctt ccttgatttt ctaaaattca atcgctttct attcgtcctt tgtatcttat
    24661 ttaatgtcgc cctgagaggc gacgaataga aaggagaagg gtgctccgta tttgctgaac
    24721 tgaatacggg ctacggatgg tgctaaaaag atagttattc ctagaactga cagttcttcg
    24781 tcataactcc tattttagct ttgtccgctt gacgccctta atatcttata tatgcctaaa
    24841 cgtactgata ttcaaaaaat tatggtgatt ggttctggtc cgattattat tggtcaggct
    24901 gctgagtttg actacgctgg gacccaggct tgcttgtcgt tgaaagagga aggttatgag
    24961 gttgttttgg ttaactcaaa tcctgcaacc atcatgacgg acaaggaaat tgctgataag
    25021 gtttacattg aaccgattac acttgagttt gtgacacgta ttcttcgtaa ggaacgtcca
    25081 gatgccttgc taccaacact cggtggtcag acaggtctca acatggccat ggaattgtct
    25141 aaaaatggca tcttagatga gcttggtgta gagcttctcg gtactagatt gtctgccatt
    25201 gaccaagcgg aggaccgtga cctctttaaa caattgatgg aagagcttga gcaacccatt
    25261 ccagaatctg aaattgttaa cacagtagaa gaagcaattg cctttgcagc gacaattggc
    25321 tacccagtca tcgttcgtcc agcctttacc cttggtggta ctggtggtgg tatgtgtgcc
    25381 aacgagaaag aattgcgtga aatcactgaa aatggtttga aattgtcacc tgttacccaa
    25441 tgtttgattg agcgttcgat tgccggtttc aaggaaattg aatacgaagt gatgcgtgac
    25501 tcagctgaca atgccttggt tgtttgtaac atggaaaact ttgacccagt tgggattcac
    25561 acaggggatt ccattgtatt tgcccctgcg caaaccatgt cagactatga aaaccaaatg
    25621 cttcgtgatg cgagcttgag cattattcgt gccctcaaga ttgaaggtgg atgtaatgtt
    25681 cagctagctc ttgatcctaa cagcttcaag tattatgtta tcgaagtaaa ccctcgtgta
    25741 tcacgttcgt cagcccttgc ttctaaagcg acaggatatc cgattgctaa gttggctgcc
    25801 aagattgcag taggtttgac cttggatgag gttataaacc cagttacagg ttcaacctat
    25861 gccatgtttg aaccagccct tgactacgta gttgctaaga ttccacgttt cccatttgac
    25921 aagtttgaaa agggtgaacg ccgtctcggt acacaaatga aggcgactgg agaagtcatg
    25981 gcaatcggtc gtaacatcga ggaatctctt ctcaaggcct gccgctccct tgaaattggg
    26041 gtgcaccaca atgaaatacc tgaacttgca gcagtttctg atgatgcctt gattgaaaag
    26101 gttgtcaaag cccaagatga ccgtctcttc tatgtgtcag aagccattcg ccgtggttac
    26161 acacctgaag aaattgcaga gcttacaaaa attgatatct tctatcttga taaactcttg
    26221 catatctttg aaattgagca agaattgggt gctcatccac aagatctaga agttttgaaa
    26281 acagccaaac ttaatggttt ttcagaccgt aagattgctg aactctgggg aacgactgat
    26341 gatcaagttc gccaacttcg tttggaaaac aagattgtcc cagtttataa gatggtagac
    26401 acttgtgcgg cagagttcga ctctgaaacg ccatatttct attcaaccta tggttgggaa
    26461 aatgaatcta tcagatctga taaagaatct gtacttgtcc taggttcagg tccaatccgt
    26521 atcggtcaag gggttgagtt tgactacgca accgttcact ctgttaaggc tatccaggca
    26581 gctggttatg aagctattat catgaactca aacccagaga ccgtttcaac agacttctct
    26641 gtatcagata agctttactt tgagccattg acattcgaag atgttatgaa cgtcattgac
    26701 ttggaacaac caaagggagt tatcgttcag ttcggtggtc aaacagccat caaccttgcg
    26761 gagccattgg caaaagcagg tgtgaccatc cttggtacac aggttgctga cctagaccgt
    26821 gccgaagacc gtgacctctt cgagcaagct ctcaaagaat tggatattcc acagccacca
    26881 ggacaaacgg ctaccaatga agaagaagca gctcttgcag ctcgtaagat tggcttccca
    26941 gttcttgtcc gcccatctta tgtacttggt ggacgtgcca tggaaatcgt tgaaaacgaa
    27001 gaagaccttc gttcttacat gcgaactgct gttaaggcta gtccagacca cccagttctt
    27061 gtcgactctt acatcgttgg gcaagagtgc gaagttgatg ccatttcaga tggtaaaaat
    27121 gtactcattc ctggtattat ggagcatatc gaacgtgctg gtgtccactc aggtgactca
    27181 atggctgttt acccaccaca aaccttgtcg caaaaggttc aggagaccat cgcagactac
    27241 accaaacgct tagcaatcgg tcttcactgc cttggaatga tgaacatcca gtttgttatc
    27301 aaggatgaaa aagtctacgt tattgaggtc aatccacgtg ccagccgtac agttccattc
    27361 ctatctaagg taaccaatat tcctatggct caagtagcga ccaagctcat tcttggtcaa
    27421 agtttatcag aacttggcta ccaaaatgga ctttaccctg aaagcacccg tgttcatatc
    27481 aaggcacctg tcttctcctt taccaaacta gctaaggtag acagcttgct cggtcctgaa
    27541 atgaagtcaa caggtgaagt tatgggttct gatgctactt tggaaaaagc tctctataaa
    27601 gcctttgaag cttcttatct acacttgcca acttttggta atgtcgtctt taccatcgct
    27661 gatgatgcca aagaagaagc cttgaacttg gctcgtcgtt tccaaaacat tggttatgga
    27721 atccttgcga cagaagggac agcagccttc tttgctagtc atggcttgca agcccaacct
    27781 gttggtaaga ttggtgatga tgataaggat atcccaagtt ttgtacgcaa aggaagaatt
    27841 caagctatca ttaacacagt aggaacaaaa cgaactgctg acgaagatgg tgagcaaatt
    27901 cgtcgttcag ccattgaaca cggggtgccc ctcttcacag cgctagatac agctaatgcc
    27961 atgcttaagg tacttgaaag tcgtagcttt gttacagaag cgatttaaat agaaaaataa
    28021 ggtatagcag actgaattta gaacagtaca cagggatact aaaatatttc tagaaattaa
    28081 tttgaatttt ctaattgatt cgttcgcatc ttatttcaat ctactataga aaaaagtctt
    28141 taaaattata aaacgcatca tatcaaggtt tttcaaaaac cttgatatga tgcgttttat
    28201 tgtgggaata tgtatttcat tttctactaa aattatgttt ttgaataacc tctatcttag
    28261 tagtttgtat aatacccctc aatcagtttt tgcgataagc tttaatgcta tgactatacc
    28321 actcttgcat ttcttttgat ggtggtgtca tataatcgcc atacatctgg gttaaaaatt
    28381 ggtcatattt tttgggaaca ggcaacatac ggccctcaaa ctcagttaaa atcagttctt
    28441 taaaggtatc aactgggaag atttctttca tcccttcctt accgatccca actcctcctt
    28501 catattgagg agtgttggtt acagcatttt tgactagttg atcaattttc ttgtaaaagt
    28561 agcgaggatt gacaaatcgg agagcgtacc agctacataa tctaagaaaa tcttttagtt
    28621 tgctatcacc gtgaactgct cgtgattttt tgatataagc tagttgacga agagccacat
    28681 acttatagct cttgtcgaca atgctcaagt ctgtaaatcg atcaattggg aagacatcga
    28741 tgaaaaggct ggtatcatga cgcttgtact taacatggtc ttctataaca gtagaagtgt
    28801 ccaaaatcga tgcgaaatta tggaagtacc aagaagatgt atcgtaggaa agaaccttgt
    28861 agcgagggtg attttcttct tcaataatct tcagtaaacg ctcataatcc tcacgataaa
    28921 gggaaatatc aatatcatca tcccaaggaa tcataccttt gtggcggatg gctccaagca
    28981 tggttccata actgagaaaa taaggaatat catatttctt acaagtctca tcaatatagt
    29041 ccagcagggc tagttgaatt tctttaattt cttttttttc taaatattgc atcctaatcc
    29101 tccaatttat aagcgtgaaa ttcatgactg tagaagcgtt tttcttctgg tggtagggtc
    29161 atataatctc cataaaattg tgtcaaaata gtatcaaatt tttcaggtgc aggaaggctt
    29221 aaattctcaa agggtaaatc gattgtttta tcaaaggtac cacttgggaa gacttccttt
    29281 tccttaaatt ttgaagggat aaaagccata tattgcccat tttcacgact atatttttga
    29341 atttctttct cgattttatt tgcaaaataa cgaggagaaa ccggtcgaag gagtaaccag
    29401 aaggctgttc gtatccaatc ttttaaaagg ctatccttat agacaatatt tttatgttta
    29461 ctgaaagaca gcagtttgaa gctttccagt ttataacaag tatcaatgac cttaggatca
    29521 tcaaagcgat ctatagggaa aatatcgata aagataccag actcataggt ttttgtattt
    29581 cgagtatcaa taattttagt cgtactgtcg gttatcttga taaagttgtt aaagtagttc
    29641 ttatcagttt ctaaggatag gagcttatac ttgctttttt ccttttgaaa aatgttaata
    29701 aatcgttggt agtcttctct aggcatggat aaatcaatat cgtcgtccca agggataaag
    29761 ccctcatgtc gaaccgcccc aatcagagta ccgtagttaa taatatagtt gatattgtgc
    29821 tttttacaga gagtatcaat ataatccaaa atttctaatt caatttgttt ggcatcttca
    29881 acggttagtt gtttcatttt aaactcctat gattttttaa atttattttt taaggctagg
    29941 acatggttta aaaattcata gaaaatgcta tcttttgtga agacaagtag actaatataa
    30001 gagatagctg atagcaagac aatcaaacca gtattaatca aaaatggcaa attaatgacc
    30061 atatccacag gatacacgaa attaatcagg aaataaattg ctacaaagga aagtgaaaag
    30121 agagagtatc gaacagtata gctaaagata tgtcccaagt ggatgagttg ttttctatgg
    30181 atgaaaatga tatagaaaac aagtagagaa gtctctgata acatagttgt cagtaagtag
    30241 tattcaggag ccacgatatg gttgaaaaag aggagactat tcaagcccaa attgagtagc
    30301 ccagcaaaga ctgtatagac tgtgatacgt ttttcatagc cattggtaaa gagaatttgg
    30361 gaaccaagaa tggtatctaa ggccaggata atcgtacgaa aagcgaagag agaggtcaag
    30421 atgccgcctc cgatatattt ttcactaccg taaagtagga tggcatttgg tcctaaaacc
    30481 atgagtccaa aactcagtgg aatgataaag aagttaaaga ttcgactacc tctattaacc
    30541 agagaaacat aggcttcttt gtctcctttc cccagatagt aactgagacg aggcacactc
    30601 actccaattg cacctgttac aaccccagct ataacggtca caattcgctg agctatggta
    30661 tagtaactaa cgttgacatc aatccctgtt ttaacgagga agaggcgatc taaaaaagtg
    30721 aagagcatat tggcattggc aaagactaac atggctgtca gagggagaaa gagtggttta
    30781 aaatcactta ggtgaatttt aacaagtttg atgtctcttt taatccaaaa ataactaatc
    30841 aggtagttaa tcagcgtcga taaactcatc acaagtgtat agacaacaat atcgtgttca
    30901 tttttaacaa ataagaaaat agagaccagc atcaggatac ggatgaaggc agttttgtaa
    30961 aagagaaaac tgtaattttc cagagcttca ttgacccatt cgattgaaaa aatctgggca
    31021 atgagttgaa tccccataac aaggtagacc tttttgacga ttggattatc agtaaagaag
    31081 agaggatagg ctaggatata gacagcagtg gtcaaaatcg tacaagcgat gcacaaataa
    31141 aaaagactag aaaaggttct gttaagatct tttttgttat ccttgacatt actgatagcc
    31201 cttaaaccgt agttatagac accataagtt gcaaagggca agaaaaatga caaaatagtg
    31261 tcgactgagt tgaagtaacc atagtcagtt cggtccaaga cacgcgcgac ataggttcca
    31321 gttaggatgg gaaaaataat attcaagaca cgaattccca tgtaagatag agcatttaat
    31381 tttatacttt tcattcaatt tacctcgttt ttcattatat cataaagtta gctaataaga
    31441 aatgaagggc agtaagtcaa gtaatcactt tgaagtttca aatcttaaat tttaagtttt
    31501 ctttaaggaa agtatattat tctgaaggac tctaaaattt cgcagtcatt tattagtaat
    31561 tgctacagaa ttcctagtca ttactagaaa taggcttgtt tctttgaata atagaactgc
    31621 ataattctcc tattctagaa ggggaggacc agtatttctt tcatgatagg actagattgt
    31681 ggtatatagg actagattgt ggtataatag agagaataag tttttttagt aagacaaagg
    31741 agaaaataga tgatttatgc aggaattctt gccggtggaa ctggcacacg catgggaatc
    31801 agtaacttgc caaaacaatt tttagagcta ggtgatcgac ctattttgat tcatacaatt
    31861 gaaaaatttg tcttggaacc aagtattgaa aaaattgtag ttggtgttca tggagactgg
    31921 gttttacatg cagaagatct tgtagataaa tatcttcctc ttcataagga acgtattatc
    31981 attacaaagg gtggtgctga ccgcaataca agtattgaga acatcattga agccattgat
    32041 gcttatcgcc cgcttactcc agaggatatc gttgttaccc acgattctgt tcgtccattt
    32101 attacgcttc gcatgattca agacagtatc aaacttgctc aaaatcatga cgcagtggat
    32161 acagtagtag aagcagtgga tactatcgtt gaaagtacca atggtcaatt cattacaggt
    32221 attccaaatc gtgctcacct ctatcaggga caaacacctc aaacattccg ttgcaaggac
    32281 ttcatggacc tttatggatc tctttctgat gaagagaagg aaatcttgac agatgcatgt
    32341 aaaatctttg tgatcaaagg aaaagatgta gccttggcca aaggcgaata ctcaaatctg
    32401 aagattacaa ccgtaacaga tttgaagatt gcaaaaagta tgattgagaa agactagtaa
    32461 aatgattaat caaatttatc aactaactaa acctaagttt atcaatgtca aatatcagga
    32521 agaggctatt gaccaagaga atcatatcct tatccgtccc aactacatgg ctgtctgtca
    32581 tgcggatcag cgttactacc agggaaaacg tgatcccaag attttgaata aaaagcttcc
    32641 aatggcaatg attcacgagt catgtggaac cgtcatttct gacccgacag gaacctacga
    32701 ggttggtcaa aaagttgtca tgattcccaa tcagtctcct atgcagagtg atgaagaatt
    32761 ctatgaaaac tacatgacag ggacccattt cttgtctagt ggatttgatg gctttatgag
    32821 agagtttgtt tctctcccta aagatcgtgt ggtggcttat gatgctattg aagatacggt
    32881 tgcagccatt acagagtttg tcagtgtggg catgcacgct atgaatcgtc tattgactct
    32941 tgctcatagc aagcgggagc ggatcgccgt tattggagat ggaagtttag cttttgtggt
    33001 tgccaatatt atcaattata ctttgccaga agcagagatt gtggttattg gtcgtcattg
    33061 ggaaaagttg gaactcttct catttgccaa agaatgctat attacggata atattcctga
    33121 agagttggcc tttgaccatg cttttgaatg ttgtggtggt gatggtactg gaccagctat
    33181 taatgacttg attcgctaca ttcgtcctca gggaacaatt ctcatgatgg gagttagcga
    33241 atataaagtc aatctcaata ctcgcgatgc cttagaaaag ggcttgctct tggttgggtc
    33301 atctcgttct ggtcgcattg attttgaaaa tgctatccaa atgatgaaag tcaagaaatt
    33361 tgccaatcgt cttaaaaata tcctttatct agaagaacct gtaagagaaa ttaaagatat
    33421 tcaccgtatc tttgcaaccg atttaaatac agcctttaaa acagtgttta agtgggaagt
    33481 ataagtcctg gaggttaatt gtggagaaaa tcattaaaga aaaaatttct tccttactta
    33541 gtcaagaaga agtcctcagt gttgaacaac taggtggaat gaccaatcaa aactatttgg
    33601 ctaaaacaac aaataagcaa tacattgtta aattctttgg taaagggaca gaaaagctta
    33661 tcaatcgaca agatgaaaag tacaatcttg aactactaaa ggatttaggc ttagatgtaa
    33721 aaaattatct ttttgatatt gaagctggca tcaaagtaaa tgagtatatc gaatctgcga
    33781 ttacgcttga ttcaacgtca atcaagacca agttcgacaa aattgctcca atattacaaa
    33841 ctattcatac atctgctaag gaattaagag gagaatttgc tccttttgaa gaaatcaaaa
    33901 aatacgaatc cttgattgaa gaacaaattc cttatgccaa ctatgaatct gttagaaatg
    33961 cagtcttctc cttagagaaa agactggctg acttaggtgt tgacagaaaa tcttgtcata
    34021 tcgatttggt gcctgaaaac tttatcgaat cacctcaagg acgactttat ttgattgact
    34081 gggaatattc atcaatgaat gatccaatgt gggatttggc tgccctcttt ttagagtctg
    34141 aattcacttc ccaagaggaa gaaactttct tatctcacta tgagagtgac caaacaccgg
    34201 tttctcatga aaagattgct atttataaaa ttttacaaga tactatttgg agtctatgga
    34261 ctgtctataa ggaagagcaa ggtgcagatt ttggttacta tggtgtgaat cgttaccaaa
    34321 gagctgttaa aggtttggct tcttatggag gaacagatga aaagtaaaaa cggagttcct
    34381 tttggccttc tctcaggtat tttctggggc ttgggtctaa cggttagtgc ttatatcttt
    34441 tcgattttta cagatttgtc accctttgtg gtggctgcag ctcatgattt tttgagcatc
    34501 tttatcttac tagcttttct cttggtaaaa gaagggaaag ttcgcctctc aattttctta
    34561 aatattcgca atgtcagtgt tatcatcgga gccttgctag caggccctat cggtatgcag
    34621 gccaatcttt atgcagttaa gtatatcgga agttctttag cttcatctgt atcggctatt
    34681 taccctgcga tttcagttct attggctttc ttctttttga agcacaagat ttcgaaaaat
    34741 actgtatttg ggattgtctt gattattgga gggattattg cccagaccta taaggttgaa
    34801 caggttaatt ccttctacat tgggattctc tgtgctttgg tttgtgctat tgcatgggga
    34861 agtgagagtg ttcttagctc ctttgctatg gaaagtgaac tgagtgaaat cgaagccctc
    34921 ttaatccgtc aagtgacttc gttcttgtcc tatcttgtga ttgtgctctt ctctcatcag
    34981 tcatttactg tagtagccaa tggacaattg ctaggtctca tgattgtttt tgcagccttt
    35041 gatatgattt cctacttggc ttattatatc gctatcaatc gtttgcaacc agccaaggct
    35101 acaggcttga acgtgagcta tgtagtatgg actgtcttgt tcgcagctct tttcttggga
    35161 acatcattag atatgctgac cattatgacg tcacttgtcg tcattgctgg agtttatatt
    35221 attattaaag aataaaggag attcgtgtga aagccattat cttagcagcg ggattgggaa
    35281 ctcgcttgcg tcctatgact gaaaataccc ctaaagcctt ggttcaggtt aatcaaaaac
    35341 ctttgattga ataccaaatt gagtttctca aagaaaaagg aatcaatgac atcatcatca
    35401 tcgttggtta tcttaaagaa caattcgatt atttaaaaga aaaatacggt gttcgcctcg
    35461 ttttcaatga taaatacgct gactacaata acttttactc tctctatctt gtaaaagaag
    35521 aattggccaa cagctatgtt attgatgctg acaattatct ctttaaaaat atgttccgca
    35581 atgatttgac acgttcgact tattttagtg tttatcgtga agattgtacc aacgaatggt
    35641 tcttggtcta tggagatgac tacaaggttc aagacattat tgttgatagc aaggcaggtc
    35701 gcatccttag tggtgtatcc ttctgggatg ctccaactgc agaaaagatt gtcagcttta
    35761 tcgacaaggc ttatgcaagt ggtgaatttg ttgatctcta ttgggacaat atggttaagg
    35821 ataatatcaa agagctagat gtctatgttg aagaattaga aggcaatagc atttatgaga
    35881 tcgatagtgt ccaagactat cgtaaattag aagaaattct taaaaacgaa aattaaagat
    35941 tccaacatct gacaaaatag tcggatgttt tttgattttt tacgaacttt tacgaataga
    36001 tagatgagta gaaaaagaaa tggagttatt tatgaaaatc acaaactatg aaatctataa
    36061 gttaaaaaaa tcaggtttga ccaatcaaca gattttgaaa gtgctagaat acggtgaaaa
    36121 tgttgatcag gagcttttgt tgggtgatat tgcagatatc tcaggttgcc gtaatccagc
    36181 cgtttttatg gaacgttatt ttcagataga cgatgcgcat ttgtcgaaag agtttcaaaa
    36241 atttccatct ttctctattt tagatgactg ttatccttgg gatttgagtg aaatatatga
    36301 tgcgcctgta cttttatttt acaagggaaa tcttgacctc ctgaaattcc cgaaggtagc
    36361 ggtcgtgggc agtcgtgctt gtagcaaaca gggagctaag tcagttgaaa aagtcattca
    36421 aggcttggaa aatgaactgg ttattgtcag tggtctggcc aagggcattg acacagcagc
    36481 tcatatggca gctcttcaga atggcggaaa aaccattgca gtgattggaa caggactgga
    36541 tgtgttttat cctaaagcca acaaacgctt gcaagactac atcggcaatg accatctggc
    36601 tctaagtgaa tatggacctg gagaacaacc tctgaaattt cattttcctg cccgtaatcg
    36661 catcattgct ggactttgtc gtggtgtgat tgtagcagag gctaagatgc gttcaggtag
    36721 tctcattacc tgtgagcgag caatggaaga aggacgcgat gtctttgcta ttcctggtag
    36781 cattttagat ggactatcag acggttgcca tcatttgatt caagaaggag caaaattggt
    36841 caccagtggg caagatgttc ttgcggaatt tgaattttaa aaatgaccta agctagaatt
    36901 ctaagaaaaa atcaatttta agagaaaatg aacccaacat ttccataata aaacgcatat
    36961 tagcaagttt ttaacacttg ataatatgcg ttttttctaa gtggattagt agagtagagg
    37021 attttttcat ataatactct tcgaaaatct cttcaaacta cgtcagcttc catctgcaac
    37081 ctcaaaacag tattttgagc tgacttcgtc agtcttatct acaacctcaa agcagtgctt
    37141 tgagcaacct gtggctagct tcctagtttg cgctttgatt ttcattgagt ataagggaaa
    37201 gtatagtgaa ttgaaataag atgtgaacaa ctctatcagg aaagtcaaat taatttatag
    37261 aaatatttta gcagccaagg tgcactgtta tagattcaat acactataat ttagtgtaat
    37321 tgagaaagga gaaatgattg tgattgatgt tggctaggtt atgttcaatg attcctaccg
    37381 tctcaaatct tgtcagtaag gaaaaataaa ttcttcaaaa gtagagatta caaggcttgt
    37441 ttaagaaaga attcaaagac cttgacaaat aaaaataaaa tggttattat aaaaaatggt
    37501 ctgaaataga tgatgatact tttcgaaaat ctcttcaaac tacgtcagct cagctttgcc
    37561 ttgctgtgtt ttgagcaagc tacggttagc ttccgagttt gattttcatt tactagaaat
    37621 gaaactgatg agagatatca gtagacattt gagtcaggat attatggaaa atgataaaaa
    37681 gagctcgtga gattggcata tcagactact aaagtattga gtttgttagg attttagcga
    37741 ctagttagct gggaaaggaa gatatttgtg acaaataata aactgtattc gttgatagaa
    37801 tttagaaata aaatatatga agaattagaa ctttccagaa gtgatttagc gattttacta
    37861 tgtgccatgc ttatcgcctc tatcggatta aatatggatt cgactcccgt gattattgga
    37921 gccatgttaa tctctccttt gatgacacct attctgggag tggggctctc tctagctata
    37981 tttgatttta aattgttaag aaaatctttt aaaatattag ctattcaaat tcttgccagt
    38041 ctaatagctt caacacttta tttttatctt tctcccattt cgtatgctag ttcggagatt
    38101 gttgctagaa cctctccgac tatttgggat gttctcattg cttttgtagg agggatagca
    38161 ggtattattg gtgctaggaa aaaagagacc aataatattg ttcctggtgt tgctattgca
    38221 accgccttga tgcctcctct ttgtacagta ggttatgcta ttgcttctgc taatctaaaa
    38281 tttatcatag gctcctctta cctattcctc atcaattgta gctttattgt cattgcgact
    38341 tatataggtg ttaggttgat gatggttaag aaacattatt ttaaagataa tgaagaagac
    38401 tctaaaatgc gtaggatttt gcttctagtt gctgttttgc tgatgattcc gagtttcatc
    38461 tctgcaacga ctttagtgag agaaacgttg aaaaaagagt cccttaagaa atttatatca
    38521 gagcagtttc aggggtataa tattttgaaa aaaacctatt ctaaaaagac tcatacccta
    38581 aagctaacca tttcaggaaa ttatttgaca gaagaagaac tcgatatgat ttcaagtaag
    38641 agaggtgact atggtttaag tgatgtttct gttcaagttt cacaattgtc tgattcagaa
    38701 caacttagta aggaagagct ggtggagtat ttcttccagt atatcaagga taaggaagca
    38761 aaagaaaagg agaaagccaa taaatttgat acagagtctg aggagcaata atttcttgag
    38821 aatagctggt ttctctcgtg agtcttctat gtatatcaaa ggaagactga ggttttaagt
    38881 ataaaacttt tcttctatta tagtagctaa gtcttgacag ggttcaaaaa atggtttaca
    38941 ctttataaag tttattactt tgaaaaggtg tgatactgtg gctacggcaa caaaaaagaa
    39001 aaaatcaaca gttaaaaaaa atctagtcat cgtggagtcg cctgctaagg ccaagacgat
    39061 tgaaaaatat ctaggcagaa actacaaggt tttagccagt gtcgggcata tccgtgattt
    39121 gaagaaatcc agtatgtccg tcgatattga aaataattat gaaccgcaat atattaatat
    39181 ccgaggaaaa ggccctctta tcaatgactt gaaaaaagaa gctaaaaaag ctaataaagt
    39241 ttttctcgcg agtgacccgg accgtgaagg agaagcgatt tcttggcatt tggcccatat
    39301 tctcaacttg gatgaaaatg atgccaaccg tgtggtcttc aatgaaatca ccaaggatgc
    39361 agtcaaaaat gcttttaaag aacctcgtaa gatcgatatg gacttggtcg atgcccaaca
    39421 agctcgtcgg atcttggatc gcttggtagg gtattcgatt tcgcctattt tgtggaagaa
    39481 ggtcaagaag ggcttgtcag caggtcgcgt tcagtccatt gcccttaaac tcatcattga
    39541 ccgtgaaaat gaaatcaatg ccttccagcc agaagaatac tggacagttg atgctgtctt
    39601 taaaaaggga accaaacaat ttcatgcttc cttctatgga gtagatggta aaaagatgaa
    39661 actgaccagc aataacgaag tcaaggaagt cttgtctcgt ctgacgagta aagacttttc
    39721 agtagatcag gtggataaga aagagcgcaa gcgcaatgct cctttaccct ataccacttc
    39781 atctatgcag atggatgctg ccaataaaat caatttccgt actcgaaaaa ccatgatggt
    39841 tgcccaacag ctctatgaag gaattaatat cggttctggt gttcaaggtt tgattaccta
    39901 tatgcgtacc gattcgactc gtatcagtcc tgtagcgcaa aatgaggcgg caagcttcat
    39961 tacggatcgt tttggtagca agtattctaa gcacggtagc aaggtcaaaa acgcatcagg
    40021 tgctcaggat gcccatgagg ctattcgtcc gtcaagtgtc tttaatacac cagaaagcat
    40081 cgctaagtat ctggacaagg atcagcttaa gctatatacc cttatctgga atcgttttgt
    40141 ggctagccag atgacagcgg ccgtttttga taccatggct gttaaattgt ctcaaaaagg
    40201 ggttcaattt gctgccaatg gtagtcaggt taagtttgat ggttatcttg ccatttataa
    40261 tgattctgac aagaataaga tgttaccgga catggttgtt ggagatgtgg tcaaacaggt
    40321 caatagcaaa ccagagcaac atttcaccca accgcctgcc cgttattctg aagcaacact
    40381 gattaaaacc ttagaggaaa atggggttgg acgtccatca acctacgcgc caaccattga
    40441 aaccattcag aaacgttatt atgttcgcct ggcagccaaa cgttttgaac cgacagagtt
    40501 gggagaaatt gtcaataagc tcatcgttga atatttccca gatatcgtaa acgtgacctt
    40561 cacagctgaa atggaaggta aactggatga tgtcgaagtt ggaaaagagc agtggcgacg
    40621 ggtcattgat gccttttaca aaccattctc taaagaagtt gccaaggctg aagaagaaat
    40681 ggaaaaaatc cagattaagg atgaaccagc tggatttgac tgtgaagtgt gtggcagtcc
    40741 aatggtcatt aaacttggtc gttttggtaa attctacgct tgtagcaatt tcccagattg
    40801 ccgtcatacc caagcaatcg tgaaagagat tggtgttgag tgtccaagct gtcatcaggg
    40861 acaaattatt gagcgaaaaa ccaagcgtaa tcgcctcttc tatggttgca atcgctatcc
    40921 agaatgtgaa tttacctctt gggacaagcc tgttggtcgt gactgtccaa aatgtggcaa
    40981 cttcctcatg gagaaaaaag tccgtggtgg tggcaagcag gttgtttgta gcaaaggcga
    41041 ctacgaggaa gaaaagatta aataagagga ggggcccgaa agtaaatttc aggctccttt
    41101 tggttagaac ttgacaaaat acatcatttt atgcgaaact agaagaagat tattttaact
    41161 aggagaagtt atgcgtctta tctatctgat aattggtttt ttatcactgg ccttggctat
    41221 tgttggggtt gttttaccct tgttgcctac aacacctttc cttttgttgt ctattgcttg
    41281 tttctccaga agttccaagc gattcgaaga ctggctttat cataccaagc tctatcaaac
    41341 atatgtagct gattttcgcg agactaagtc tattacgcgt gaacgaaaga aaaaaatcat
    41401 cgtatccatt tacattttga tggggatttc tatttatttt gcccctctct taccagtcaa
    41461 aatcggtctg ggtgctttga ccatctttat cacttattat ctcttcaagg tcattccaga
    41521 caaagaatag ttaaaacagt agttatttac cttgataaaa ttgaaagcat attcataaca
    41581 atatgatata ataaatttga agtaatattc aaggagaatc aaatgattta cgaattttgt
    41641 gctgaaaatg tgactttact tgaaaaagcg atgcaggctg gagctcgtcg gattgaactc
    41701 tgtgataatc tagcagttga tgggacaaca cccagctatg gagtgactaa ggcagcggtt
    41761 gaactggcag ctaactacga tacaaccatc atgaccatga ttcggccacg tggtggtgac
    41821 tttgtctata atgacctaga aattgctatc atgctagaag acattcgttt gactgctcag
    41881 gctggaagtc aaggggttgt atttggagct ttaactgctg ataaaaagtt ggataagcct
    41941 aatctggaaa agttaattgc tgcatcaaaa ggaatggaaa ttgtctttca catggccttt
    42001 gatgaactaa gtgatgaaga tcaaccggaa gctattgact ggctcagtca agccggtgtc
    42061 actcgtatcc taactcgtgc tggtgtgtct ggcgactcct tagaaaaacg ttttgttcac
    42121 tatcacagaa ttttggagta cgctaaaggt aaaattgaaa ttctaccagg tggggggatt
    42181 gaccttgaaa accgtcaaac ctttatcgac caggtggggg taacacaatt gcatggtact
    42241 aaggttgttt tttaaaaaat agaaaggaac tgctagcttt gggtagcagt tttcacttat
    42301 gtttgaaatt tttaaatcct atcaatttaa tcaagaaaag gctcatgatt atggttttat
    42361 agaaaatagc gaagtctgga catatagttg ccagattttg caaggtgact ttgtcatgac
    42421 tgtgtccatc actgctgata atgtgaactt tcaagtcttt gaccaagaga ctggtgacct
    42481 ctatcctcac gttcatatgg aaagcatgag gggaagtttt gtcggaaatg tccgtgaggc
    42541 ttgtctggag attctttacc agattcggaa ggcttgtttt gatgtgcaag attttatctg
    42601 tcatcagact aagcgtatca tgactcaagt tcaggaaaag tatggaaacc agttggagta
    42661 tctgtgggaa aaatcgcctg atacagctgt attgcgccat gaaggcaatc aaaagtggta
    42721 tgccgtcttg atgaaaatct cttggaataa gctggaaaag ggcagagaag gacaagtgga
    42781 agcagtcaac ctcaagcatg accaagtagc taatttactt tcacaaaagg ggatttatcc
    42841 agcctttcat atgagcaagc gctactggat tagtgtgtcc cttgatgata ctttatcaga
    42901 tgaagaagta ctggaattga tagaaaaaag ttggaactta acctctaaaa aatgaaatat
    42961 tttaataatt ttcatgaact ttcaattagc taaatattct ttactgaaga aattttcaga
    43021 aaatatagaa tttaccgcgc cagaggaata tggtgccatc ttcaaatacc tgattgagaa
    43081 tgtcaagacg gatcgtcaga tcatctattc gcctcactgt catgatgacc tcggaatggc
    43141 agtgacaaat agtcttgctg ctgtcaagaa tggtgcagga cgtgttgaag ggactatcaa
    43201 tggtattagg gagcgagctg gaaatgctgc tttggaagaa attgcagtgg ctctcaatat
    43261 tcgccaagat tactaccaag tagaaaccag tattgtccta aatgagacca tcaatacgtc
    43321 agaaatggtt tctcgcttct ctggtattcc agttcctaaa aacaaagccg tcgttggtgg
    43381 caataccttc tcccacgaat ctggtattca ccaagatgga atccttaaaa atcctctcac
    43441 ttatgagaac atcacacctg aattggttgg tgttaagatt ccgcttgtaa aattatctgg
    43501 tcgccatgct tttgttgaga aactgagaga attggcccta gattttacag aagaggatat
    43561 caaaccactc tttgctaagt tcaaggcact ggtcgataag aagtaagaaa tcacagatgc
    43621 agatattcga tctttggtag ctggaaccat ggttgaaaat ccagaaggct tccactttga
    43681 tgatttacaa cttcaaactc atgcagataa tgacattgaa gcgctcgtta gcctagccaa
    43741 tatggatggt gagaaagtcg aatttaatgc gacagggcaa ggttccgttg aagcaatctt
    43801 taacgctatc gataagttct ttaatcaatc tgttcgtttg gtgtcctaca ctatcaatgc
    43861 ggtaacagat ggaatcgatg cccaggatcg ggttttggtc actgttgaaa acagagatac
    43921 agaaaccatc tttaatgcag cagggcttga ttttgatgtg ttgaaggctt ctgctattgc
    43981 ctatataaac gctaatacct ttgttcaaaa agagaatgca ggtgagatgg gacgcagtgt
    44041 ttcttaccac gatatgccta gtgtgtaaag gagaaggcta tggcaaagaa aatagtagct
    44101 ctagtaggag acggaattgg cccagaaatc atggaggttg gtttagaagt tctggaggct
    44161 ctagctgaaa aaacaggttt tgactatgag attgacagac gaccgttcgg aggtgcagat
    44221 attgatgcag caggacctcc cttacctgat gaaaccctta aggcaagtag ggaagcagat
    44281 gctatcctac tagcagctat cggtagtcct cagtatgatg gagcagcggt tcgccctgaa
    44341 caaggcctga tggctctccg taaggaactc aatctttacg ctaatattcg tcctgtaaaa
    44401 atctttgaca gtctcaagta tttgtcacca ctcaaaccgg aacgaatttc tggtgtagac
    44461 tttgtcgtgg tgcgtgaatt gacaggcgag atttactttg gagatcatat tcttgaagag
    44521 cgcaaagcgc gtgatatcaa cgactatagc tatgaggaag tggagtggat tattcgcaaa
    44581 gcctttgaaa ttgcaagaaa tcgcagaaaa atccttacta gtatcgataa gcaaaatgtt
    44641 ctagcgacct caaaactctg gcggaaagta gctgaggaag tcgcacagga tttctcagat
    44701 gtaaccttgg aacaccagct ggtagactca gctgctatgc ttatgattac caatcctgct
    44761 aagtttgatg ttattgtaac ggagaatctt tttggagata ttttatctga tgaatcaagc
    44821 gtcttatctg gtacacttgg ggttatgcca tcagccagtc attctgaaaa tggaccaagt
    44881 ctctatgaac ctatttacgg ttcagcacct gatattgcag gtcaaggaat tgccaatcct
    44941 acttccatga ttttatcagt tgccatgatg ttgagagata gtttcggacg ttatgaggat
    45001 gcagagcgta tcaaacgtgc tgttgagaca agtctggcgg caggaatttt aacgagagat
    45061 ataggaggtc aggcttcaac aaaggaaatg acggaagcta ttattgcaag gttatgaagt
    45121 tagacgaaaa aattactcta gtccttttga tttggaatgt catcattttc ttgatttatg
    45181 gcattgacaa attcaaggca agaagaagaa cttggcgcat ccaagagaaa atcttactca
    45241 ttttagccct tacttgtggt ggttttgggg cctggttagc tggaatcact tttcaccaca
    45301 agactcgaaa atggtacttt aaaacagttt ggtttcttgg gatggtgacc acactagtag
    45361 ccttatattt tatttggagg taatggatgg cagggtcttc gagggaacac gctgcttggg
    45421 ctctagcgga ctatggtttt aaggtcgtga ttgcaggatc tttcggtgac attcattaca
    45481 ataatgaact caataatggc atgttgccaa tcgttcagcc tagagaggtt agagagaaac
    45541 tagcccagct aaaaccaacc gaccaggtaa ctgtggactt ggaacaacaa aaaatcatct
    45601 cactagttga agaattcacc ttcgagatag atagcgagtg gaaacataaa ctcctaaata
    45661 gtttggatga tatcggtatt accttgcagt atgaagagtt gattgctgct tatgaaaaac
    45721 aacgaccagc ctactggcag gattagaaaa aatagaaaag gaaatatagt aaactgaaat
    45781 aagatgtaaa caaatgaatt ggagcttaac atccatttcc agcaattttt tagaaactac
    45841 agtggactat tctggattca acacattata aaattatgac aaaacacatt cacaagaagg
    45901 ctacgacatt ttaaaaggtg agggcggatg tatcgtttgc cctactaaag ttggttacat
    45961 tatcatgacc agcaacaagg cagaacttga gcgtaagttc gcagccaaag aacgtaagcg
    46021 taacaaacca ggtgttgttc tctgcggtag catggatgaa cttcgcgctt tagcgcaact
    46081 caacccagaa attgaagcat tctactaaaa acattgggat gaagatattc ttcttggttg
    46141 tatccttcct tggaaaccag aagcctctga aaaactcaaa gcatacgggg atggccgtga
    46201 agaacttatg actgatgtac gtggtactag ctgttttgtt atcaagtttg gaaaagcagg
    46261 tgaacaattg gttgccaagc tttgggaaga aggtaaaatg gtctacgcct catctgcttc
    46321 aatgacaaaa cgattgaaac tcgctatgag caaggtgtaa tggtgtctat ggtcgataag
    46381 gacggcaaac tcatcccaga acaaggagga gcacgttcaa cttcaccagc tccagttgtg
    46441 atccgtaaag ggcttgacat tgataaaatc atgatgcacc tgtcagatac ttttaactta
    46501 tgggactacc gtcaggttga gtattattag gatagagaag aagtctagtg ttaaggacat
    46561 tacagctcat aatactaggc ttttttatag aaattctttt ctttttctat aggatatggt
    46621 attctatgta gaaaatatat gttaataagt aatgccaata tttaaacatc attagtaaaa
    46681 ggagttagat tgatgaataa aagaaaagtt agtttagaag atttttataa atggtatagt
    46741 ctaaataaag aagagttatt aaataaggca actgttggtg aaaagtttaa tgataaatta
    46801 aaagaagagt ttctccagga atggcctttg gataggattt taacaatgtc aatcgatgaa
    46861 tatgtaatag gaaagggaca gcaaaataag tctttatgct acgctcttga gaagggaaaa
    46921 tacaaaaatc tatttcttgg aatttctggt ggctcagctt caaaatttgg tatttattgg
    46981 aataaaaaaa caaacaaata taaagatcaa gctaataatg agatttcaga gttggatcag
    47041 cgattttcaa aattaaaatc agatttgtat gaaattatca aagaaggtat tcgttttaac
    47101 tttgaaaatc ctatttttga tatgaaaaga tcaacaaatg aatttattgg tcgttctgct
    47161 atggtgacaa aattactttg tatctatact gagggagatc ctttctttgg tgtaaatatt
    47221 aatagtcaga aagaattttg gaaccacttt gtttctcaga caaatcaagg tggaccttat
    47281 ctgcaaaatc ataaaataat tgaactggtg tccaaaactt atcctgagtt ggagccatcg
    47341 aaattaggaa ctatgctttt tgagtattct aagcttttta tggaaaataa ggaagacaat
    47401 agtacaatgg attcatcaaa caattttagt catcaattaa ctcaatctct attaaagtct
    47461 ccaaacctta tccttcgtgg tgctcctggc acaggaaaga cttatcttgc taaagaaatt
    47521 gccaaagaat taacggatgg caacgaagac caaatcggat ttgtacaatt tcacccatcc
    47581 tatgattata cggattttgt agaaggttta agaccagtat caaatgggga tggagctatt
    47641 gagtttaggc tacaggacgg tatttttaaa gatttttgtc agaaagcaaa agaaccccaa
    47701 ttgattggag gacaagataa ttttgatgag gcttgggatt cttacttaga atatataaat
    47761 gttgctgaag aaaaagaata tataacaaaa acatcttact tatctgttaa tagtagacaa
    47821 aatttgtcag taaattatga tagtggtgtt ccaggatggt cactacctag caaatatgtt
    47881 tacgagttgt ataaagataa aaattataat aagcaagaat actacaaaag tggtggaaaa
    47941 actgtcctag aaacattgag aaagagattt ggtttgaaag actatgtttc cccaacagaa
    48001 attgatactg ataagaaatt cgtcttcatc atcgatgaaa tcaatcgtgg ggagatttct
    48061 aagatttttg gcgaactctt tttctctatc gaccctggct atcgtggtga aaaaggaagt
    48121 gtttctaccc aatatgcaaa tctacacgaa actgatgaaa agttctatat ccccgaaaat
    48181 gtttacatca tcggaactat gaatgatatt gatcgttcag tggatacctt tgattttgct
    48241 atgcgtcgtc gttttcgttt tgttgaagtt actgccgagg gtcaagttgg catgttggat
    48301 aaagagctga atatccatgc agaagaagca aaaattcgtc taagaaactt gaacgctgct
    48361 atcgaaaatg ttcaggaatt aaacagtcat tatcatattg gaccaagtta ttttcttaag
    48421 ttgaaggatg tagattttga ctatgaatta ctctggtctg attatattaa gcctctccta
    48481 gaagactact tgcgaggttc ttatgatgag gttgaaactt tggaaacttt gaaaaaagca
    48541 tttgaactga caaataatga gcaaaaagat caggcagtag ctgatgacaa tgaaggcgat
    48601 gaaaacgatg atgcggatta ctgataatca acacaagatt attaaagaaa aatttgttga
    48661 agaatatcct aaactaagca atcttctttt agacagaacc ttggaaagtc tatcccaaga
    48721 tgaacgtatt ttcatttttc caaatgattt gactcatact cctgatttgg ataaggacca
    48781 aaagattttt gaaacagtca atcagaaaat caagacaggg aacgtgattg gttttcttgg
    48841 atatggtcag gaaagattaa cgatttcctc acgattttct gatgagagta atgaccattt
    48901 tttgcattat ctcttaaaca aggttcttca tatcaatctc actagtttag atgttgcttt
    48961 gtctcgtgaa gagaggcttt atcaactttt ggtgtatctc tttcccaagt atctacaagc
    49021 tgctattcga aaaggtcttt ataaggaata tcatcgattt tctcataacg acagtaatgt
    49081 taagggagtg attgatgtaa gaagccatct caagaaaaat cttcctttca cgggaaatat
    49141 tgcctacgca acgagagagt tcacctatga taatcccctc atgcagttgg tccgtcacac
    49201 tattgaatac attaagaatc agaaaagcat tggtcaaggg gtactagata atctctcaac
    49261 tagtcgtgaa aacgtatctg aaatcgtgcg tgtaacgccc tcttataaac tagctgatcg
    49321 tgctaagatt attcggggaa atcaatctaa acctatacgt catgcatact ttcacgagta
    49381 cagaaactta caagaacttt gtctgatgat cctaaaccaa gaaaagcacg gtttaggcta
    49441 tcaagatcaa aaaatctatg gtattctctt tgatgttgcc tggctttggg aagagtatgt
    49501 ttacaccttg ttgccaaaag gttttgtaca tcccagaaat aaggataaga cggatggaat
    49561 ttcagtattt tctgttggga aacgaaaagt atatccagat ttttatgaca gagaacgaaa
    49621 gattgttcta gatgcaaaat ataaaaaact ggaattgact gaaaaaggaa tcaaccgtga
    49681 ggacttattc cagctgattt cctattctta tattttaaaa gctgagaagg ctggactgat
    49741 ttttcctagt atggagcagt cagtaaatag tgaaatagga aaagtagctg gctatggagc
    49801 tcaattgaag aagtggtcta ttcgaatccc tcagaatgcc tcattctata gtacattttg
    49861 taaaatgatg gaaaattcag aagaaaattt taaagcgatt attgatgaag aagtggggag
    49921 aaaataattt cccctctttc ttttattttt aacacaagta aaacccgaac gatatatttt
    49981 aattcataaa ataatttgac aaaaactgta ctttggttta taataaatta aggaaacgtc
    50041 ggaaaaggcg tagtgatgca agagcatagg taggtcatta caaaagaaac gagacatcga
    50101 tatgttaaat gaatttccaa tttttgatta cgaagatatt caattgattc caaataaatg
    50161 tgtcattaaa agccgtgcag aagcggatac aagtgtcact ttaggaaatc acacctttaa
    50221 actacctgtt gtgccagcga atatgcagac gattttggat gaaaatgtag cagagcaact
    50281 ggctaaaggt ggttacttct acattatgca ccgttttgat gaggcaggac gcattccttt
    50341 tattaaacga atgcacgatc aagggctcat tgcttctatc tctgtcggtg ttaaggatta
    50401 tgagtatgat ttcgttagac agctcaaggc tgatgctcct gagtatatca ctattgatat
    50461 tgctcatggt catgcggata gcgtgatttc tatgattcaa cacatcaaga aagaattgcc
    50521 agataccttt gtcattgctg gaaatgtggg aacaccagaa gctgtgcgtg aattggaaaa
    50581 tgctggtgcg gatgctacta aggtcggaat cggtcctggt aaggtttgta tcaccaaggt
    50641 taagactggt tttggtacag gtggttggca gttggctgct ctacgctggt gtgccaaggc
    50701 tgcgcgtaaa ccgattatcg ctgatggagg aattcgtact cacggtgata ttgctaagtc
    50761 tatccgcttc ggtgctagca tgatcatgat tggttccctc tttgcaggac acattgaaag
    50821 tccagggaaa acgattgaag tcgatggtga acagttcaaa gaatattatg gttcagcctc
    50881 acaatatcaa aaaggtgctt acaaaaatgt ggaaggcaaa cgtatcttgc ttcctgctaa
    50941 aggtcatctg caagacactt taactgagat ggaacaagac cttcaaagtg ctatttctta
    51001 tgcaggtgga cgtcaggttg ctgaccttaa acacgttgat tatgtgatcg tgaaaaactc
    51061 catctggaat ggggatgctt cccactaaga cggggtcttt gaccaaaaaa cttgttatta
    51121 gagcaaattt ctgttataat aaaacaagtt tccaccctta gtgtaatgga tatcacgtaa
    51181 gattccggtt cttgagatgg gggttcgatt ccctcagggt ggatgtaaac atcctaaaaa
    51241 gcctttaata gggctttttt ctttatcctg acccaaattt gccgctaaaa ctgagaatct
    51301 ctgtctaaag aattcccaaa tgctttccag tcccgtttta gagtgactca gggggctttt
    51361 tttgatataa taaaaaggac tattatcagt tagaaagagg ttggtatgaa agaattacaa
    51421 actgtactaa agaatcattt tgcaatcgaa tttgcagaca aaaatttact ggaaactgcc
    51481 tttactcata cgagttatgc caatgagcac cgcctcttaa aaatttcaca caatgaacgc
    51541 ttggaatttt taggagacgc tgttctacag ttattgattt cagaatatct atataaaaaa
    51601 tatcctaaaa agcctgaagg tgacctatca aaactccgtg ctatgattgt ccgtgaggag
    51661 agtttagctg gttttgcgcg tgattgccag tttaaccagt ttatcaagtt gggtaaaggg
    51721 gaagaaaaat ctggtggtcg caatcgtgac accattcttg gtgatgcctt tgaagccttt
    51781 cttggtgccc ttcttttgga taaggatgtg gccaaggtca aggaatttat ctatcaagtc
    51841 atcattccta aggttgaagc aggcgagttt gagatgatta cagactataa aacccatctc
    51901 caagagttgc ttcaggtcaa tggtgatgtg gctattcgtt atcaggtgat ttctgaaaca
    51961 gggcctgctc atgataaggt ctttgatgta gaagttcttg ttgaaggtaa gagcatcggt
    52021 caaggccaag gtcgttctaa gaaattagca gagcaggaag ctgccaaaaa tgccgttgaa
    52081 aaggggctgg attcatgtat ttaaaggaaa tcgaaattca ggggttcaag tcttttgctg
    52141 ataagaccaa ggtcgttttt gaccaaggtg tgacggcagt tgttggaccc aatggatctg
    52201 gaaagtccaa tattacagaa agtctgcgtt gggctttggg ggagtctagt gtcaagagtc
    52261 tccgtggggg caagatgccg gatgtcatct ttgctggaac cgaaagtcgc aaaccgctca
    52321 attatgcttc tgtagttgtg actctggata atcatgacgg atttatcaag gatgcaggtc
    52381 aagaaatcag ggtggaacgc catatctatc gtagtggaga tagcgaatac aagattgacg
    52441 gcaagaaagt ccgtctgcgt gatattcatg acctcttctt ggatactgga ttgggacgag
    52501 attccttctc tattatttcc caagggaagg ttgaggagat ttttaattcc aagcctgagg
    52561 aacgacgagc tatttttgaa gaagctgctg gagttttaaa atacaagact cgcagaaaag
    52621 aaaccgagag taaactgcag caaactcagg ataatctgga ccgcttagag gacattatct
    52681 acgagttgga taatcaaatc aagcctcttg aaaagcaagc tgagaatgcc cgtaagtttt
    52741 tagacttgga aggacaacgt aaggctattt atttagatgt tctggttgct caaatcaagg
    52801 aaaataaggc agaactagag tcgacagaag aagagttggc tcaggttcaa gaactcttga
    52861 tgagttatta ccaaaagcgt gaaaaattag aagaagaaaa tcaaactctt aaaaagcaac
    52921 gccaagattt acaggctgaa atggccaaag accaaggcag tttgatggat ttgaccagtc
    52981 tgattagtga tttagagaga aaattagccc tatcgaaatt agaatctgag caagtagccc
    53041 tgaatcaaca ggaagcacaa gctcgtttgg ctgttttgga ggataagaga aattcactca
    53101 gccaagaaaa atctgataaa gaaagctctt tagtactttt agaggaaaat ctagtccaaa
    53161 ataatcaaaa actcaatcgt ttagaagctg aattgctagc tttttcagat gatcctgatc
    53221 agatgattga gcttttgcgt gaacgctttg tggcgctttt acaagaagaa gcggatgtct
    53281 caaaccaact gacccgcatc gagaatgagt tggaaaatag tcgtcagctt tctcaaaaac
    53341 aagcagatca actagaaaag ctgaaagagc aattagctac agctaaagag aaggctagtc
    53401 agcaaaaaga cgagcttgaa actgccaagg tgcaggttca gaaattattg gctgactatc
    53461 aagctattgc caaggagcaa gaggagcaaa aaacttccta tcaagctcaa caaagtcaac
    53521 tctttgaccg tctggatagt cttaaaaaca agcaggctag agctcaaagt ttggaaaaca
    53581 tccttagaaa tcacagtaac ttttatgcag gtgtaaagag tgttctccaa gaaaaagacc
    53641 gccttggtgg gattattggt gctgttagtg agcatttgac ctttgatgtg cattatcaaa
    53701 ctgccttaga gattgcactt ggagccagca gtcagcatat catcgtagaa gatgaagagt
    53761 cggcaaccaa ggcgattgat ttcctcaaac gaaatagagc tggtcgtgca accttccttc
    53821 cgttgacgac tatcaaggcg cgtacgattt ctagtcagaa ccaagatgtt atcgctgcaa
    53881 gtgcgggatt tctaggcatg gcagatgagt tggtgacatt cgatacgaga ctggaagcta
    53941 ttttcaagaa cttgctagct acgacagcga tttttgatac cgttgagcat gcgcgtgcag
    54001 cagcgcgcaa agttcgttat caggttcgta tggtgacttt ggacggtaca gagttgcgca
    54061 caggtggttc ttacgcaggt ggagccaatc gtcagaataa cagtattttc atcaagccag
    54121 aactggagca attacaaaaa gaaattgctg aagaagaagc aagtttgcgt tcagatgaag
    54181 tgagtttgaa gaacttgcaa gatgagctag ctagattgac agaaagatta gaagccatca
    54241 aatctcaggg agagcaggct cgtattcagg agcaaggctt gtccctcgcc tatcagcaga
    54301 ccagtcagca agttgaagag ctagaaactc tttggaaact ccaagaagag gaattaaatc
    54361 gtctttctga gggagaatgg caagcggata aggaaaaatg ccaagagcgc cttactacaa
    54421 tcactagtga aaagaataat ctggaagctg agattgaaga gattaagtct aataaaaacg
    54481 ccatccaaga acgttatcaa aacttgcagg aagagctagc tcaagctcgt ctacttaaga
    54541 cagaactgca agggcaaaaa cgttatgaag tgactgatat tgaacgctta ggtaaggaac
    54601 tagataatct tgatattgag caagaagaaa ttcagcgcct tcttcaagaa aaggttgaca
    54661 atcttgagaa ggttgataca gaattgctca gtcaacaggc ggaagaatcc aaaactcaga
    54721 aaacgaacct ccaacaaggt ttgattcgca aacagtttga gttggatgat atagaaggtc
    54781 agctggatga tattgctagt catttggatc aggctcgcca gcagaatgag gagtggattc
    54841 gcaagcaaac acgtgctgaa gctaagaaag aaaaggtcag cgaacgcttg cgccatctac
    54901 aaagtcaatt aacagaccag taccagatta gctatactga agctctagaa aaagcgcatg
    54961 aattggaaaa cctcaatctg gcagagcaag aagttaagga tttagagaag gctattcgct
    55021 cactgggtcc tgtcaatata gaagctattg accagtacga agaagttcac aaccgtctgg
    55081 actttctaaa tagtcagcga gatgatattt tgtcagcgaa aaatctgctc cttgaaacca
    55141 ttacagagat gaatgatgag gtcaaggaac gctttaaatc aacctttgaa gctattcgtg
    55201 agtcctttaa agtgaccttc aagcagatgt ttggcggagg tcaggcagac ttgatattga
    55261 ctgagggcga ccttttaaca gctggtgtgg agatttctgt tcaacctcca ggtaagaaaa
    55321 tccagtcgct taacctcatg agtggtggtg aaaaagctct atcggctctt gccttgcttt
    55381 tctccattat tcgtgtcaag accattcctt ttgtcatctt ggatgaggtg gaagctgcgc
    55441 tggatgaagc caatgttaaa cgttttgggg attacctcaa ccgctttgac aaggacagcc
    55501 agtttatcgt tgtaacccac cgtaagggaa ccatggcagc ggctgattcc atctatggag
    55561 tgaccatgca agaatcgggt gtttcaaaga ttgtttcagt taagttaaaa gatttagaaa
    55621 gtattgaagg atgacaatta aactagtagc aacggatatg gacggaacct tcctagatgg
    55681 gaatggacgc tttgatatgg atcgtctcaa gtctctcttg gcttcctaca aggaaaaagg
    55741 gatttacttt gcggtggctt cgggtcgggg atttctgtct ctggaaaaat tatttgctga
    55801 tgttcgtgat gacattattt tcatcgcgga aaatggcagt ttggtagagt atcaaggtca
    55861 ggacttgtat gaagcgacta tgtctcgtga cttttatctg gcaacttttg aaaagctgaa
    55921 aacgtcacct tatgtagata tcaataaact gctcttgacg ggtaagaagg gttcatatgt
    55981 tctagatacg gttgatgaga cctatttgaa agtgagtcag cattataatg aaaatatcca
    56041 aaaagtagcg agtttggaag atatcacaga tgacattttc aaatttacaa ccaacttcac
    56101 agaagaaacg ctagaagctg gtgaagcttg ggttaatgaa catgtccctg gtgttaaggc
    56161 catgacaact ggctttgaat ctattgatat tgttctggac tatgtcgata agggtgtagc
    56221 tattgttgaa ttagctaaaa aacttggtat cacaatggat caggtcatgg cttttggaga
    56281 caatcttaat gacttacata tgatgcaggt tgtgggacat cctgtagctc ctgaaaatgc
    56341 acgacctgaa attttagaat tagcaaagac tgtgattggt caccataagg aacggtcggt
    56401 tatagcttat atggagggct tataatggca gatataaaat tgattgcatt ggacttggac
    56461 gggaccttgc tgactactga taaaaggctg acggatcgta ccaaggaaac cttgaaagct
    56521 gcgcgtgatc gtggtatcaa ggtcgtattg acaactggtc gtcccttaaa agccatggat
    56581 ttctttctcc atgagttagg gactgacggt caggaagatg agtataccat tacttttaat
    56641 ggtggattag ttcagaaaaa tacaggagaa atccttgata aaacagtctt ttcatatgat
    56701 gatgtggcac gtttgtatga agaaacagag aaattatcac tgcctcttga tgccatctca
    56761 gaaggaacag tttatcaaat ccaatcggac caagaaagtc tttatgccaa attcaatcca
    56821 gctttgacct ttgttccagt ggactttgaa gacttatcta gtcaaatgac ctacaacaaa
    56881 tgcgtgactg cctttgctca agaacccttg gatgcagcca ttcagaagat ttctccagaa
    56941 ttgtttgacc aatatgaaat ctttaaatca cgtgaaatgt tgctagaatg gtcaccaaag
    57001 aatgttcata aagcaacagg tttggcaaaa ctaatcagcc atcttggaat cgaccaaagt
    57061 caagtgatgg cttgtggtga cgaggccaat gacctctcta tgattgaatg ggcaggtctt
    57121 ggtgttgcta tgcaaaacgc tgttcctgaa gtaaaggcag ccgcaaatgt agtgacgccg
    57181 atgaccaacg atgaggaagc tgtcgcctgg gctatcgaag aatatgtgct aaaggagaac
    57241 taagatatgg gattgtttga ccgtctattc ggaaaaaaag aagaacctaa aatcgaagaa
    57301 gttgtaaaag aagctctgga aaatcttgat ttgtctgaag atgttgatcc taccttcaca
    57361 gaagttgagg aagtttctca ggaagaagca gaggttgaaa ttgttgaaca agctgtgttc
    57421 caagaagagg aaatccaaga cacagttgaa gaaagtctgg atttagagcc agttgtagaa
    57481 gtttctcaaa aagaagtcga agaatttcca cactcagaag aagggaatac tgagtttcta
    57541 gagactatag aagaaaataa ttctgaagtt cttgaaccag aaaggcctca agcagaagaa
    57601 accgttcagg aaaaatatga ccgcagtctt aagaaaactc gtacaggttt cggtgcccgc
    57661 ttgaatgcct tctttgctaa cttccgctct gttgacgaag aatttttcga ggaactggaa
    57721 gaactgctga ttatgagtga tgttggtgtc caagtcgctt ctaacttaac ggaggaacta
    57781 cgttacgaag ccaagcttga aaatgccaag aaacctgatg cacttcgtcg tgtcatcatt
    57841 gagaaattgg ttgagcttta tgaaaaggat ggtagctacg atgaaagcat ccacttccaa
    57901 gataacttga cagttatgct ctttgttggt gtgaatggtg ttgggaaaac aacttctatc
    57961 ggaaaactag cccaccgcta caaacaagct ggtaagaagg tcatgctggt tgcagcagat
    58021 accttccgtg cgggtgcagt agctcagcta gctgaatggg gccgacgagt agatgttcca
    58081 gtagtaactg gacctgaaaa agctgatcca gccagcgtgg tctttgatgg tatggaacgt
    58141 gccgtggctg aaggtatcga tattctcatg attgatactg ctggtcgtct gcaaaataag
    58201 gataacctta tggctgagtt ggaaaagatt ggtcgtatta tcaaacgtgt tgtgccagaa
    58261 gcaccacatg aaaccttctt ggcacttgat gcatcaacag gtcaaaatgc cctagtacag
    58321 gccaaagaat tttcgaaaat cacaccttta acgggaattg ttttgactaa gattgatgga
    58381 actgctcgag gaggtgtggt tctagccatt cgtgaagaac tcaatattcc tgtaaaattg
    58441 attggttttg gtgaaaaaat cgatgatatt ggagagttta actcagaaaa ctttatgaaa
    58501 ggtctcttgg aaggtttaat ctaatcagaa gcaaaaatcc tgcaaggcat aaacttgcag
    58561 gaaatttttt tattctaagc gaccatcttg acgataggtg atatctggtt gccaagtcca
    58621 tttggcaccg aatttttcaa gtaggtcaaa gctggcttga ggtcccatgc ttccagcttt
    58681 atagtcatga agtggggcac cattttcagc ccagagcttt tcaatacggt caatcaactt
    58741 ccatgacgca caaacttcat cccagtggct aaagttagtt gagttgttat ttaggacatc
    58801 ataaatcaat ttttcgtatg gttctggaga agcaccagtt gcagtcgcat ctgtacggta
    58861 atcaagtgag ttaggagcca agttaaattc ttctcctact tgcttcccat ttaggctaag
    58921 agagaagcct tctgttggtt gaatatagat ggtcaaaata tttggagcaa gtggttctcc
    58981 aaagatagaa tccatttgtt taaagacgat gttgacatga gttccttttt cagtcagtcg
    59041 tttacctgta cggaaaaaga aaggaacacc acggaatcga tcgctgtcta caaagaaggc
    59101 accagatgta aaggtttcag ttgttgattc tggattcaca tttggctcgc tacgataaga
    59161 gatgtatttc atgccatcaa tcttaccaga gcggtattgc ccacggataa agtgttcttt
    59221 gagttcttca tcagttggat gatagaggtt tttaaagacc ttaatctttt cagcacgaat
    59281 ctcgtctttt gtgaagcttg ctggtttgtc catggcgagg agcgaaagaa gttgtagagt
    59341 gtggttttgg accatgtcac ggagggcacc ggattggtca tagtagccac cacgttcttc
    59401 tacacccaag cgctccgcaa aggtaatttg aacattgtcg ataaaatcct tgttccaaac
    59461 gttttcaaaa atcaagtttg caaagcgaac tgcaaagatg ctttggatca tttccttacc
    59521 aagataatgg tcgatacgga aaatttgttc ttcgtcaaat gttgctagga gttcgtcatt
    59581 caacttgttt gcagttgcgt aatctgtacc aaatggtttt tcaacgatca agcgctcaaa
    59641 acctttgcca tcgacaatgt tttcagattt gaggtgtttg gcaatggttc caaagaactg
    59701 aggtgccata gacaagaaga agagcttatt gtgttcagct tggtattttt cattaagctc
    59761 agcttgtaat tgacgcaaag caatataatg ttccgaatca ttgacatcat ggctttgata
    59821 gtagaagtgg ctagcaaatt cttgggcttg ctcggtacta tctgccaaat caaggatgga
    59881 ctcgacaact acagattcaa aatattcctt actccaaggt ctacgggcag ttccaataac
    59941 ggcaaagtgc ttggaaagat tgccggattt atatagtcta aaaagggaag ggtagagctt
    60001 gcgtttagcc aggtctccac tcgcaccgaa aattgtaaca ataaccttag atgacatcta
    60061 gctacctaat ttctattttt attcctagtc ttgctaggta tgaggaaacc tcatttcata
    60121 aacttaattc taacataatt ttccgaaaaa tcaaaaattc caatacgagg tagaaaaact
    60181 gcaaggaaat ccttacagtt tgagtttaga cgtttaagac cttatctaag aactctttca
    60241 gacgagggtg ttgtgggtta tcaaagattt ggtcaggtgt tccgtcttca aggaactcgc
    60301 catctgcagt aaagataacg cggttggcaa cctgacgagc aaatcccatc tcatgggtta
    60361 cgataatcat ggtcatgcct tgctcagcca attccttcat aacgttaagt acgtctccaa
    60421 ccatctcagg gtcaagggca gaagttggtt catcgaagag catgatgtct ggattcattg
    60481 ctaggccacg agctatggcc acacgttgtt tttgaccacc tgataggcta tctggattgg
    60541 cattagcttt atctgctagt ccaacctttt caagcaactc cattcccaat ttctcagctt
    60601 cttccttagt catcaacttg tgctcaatag gagcaaaggt gatgttgtcc aatacagaca
    60661 tatgagggaa gaggttgaag tgttggaata ccatgccgat attttcacgg acgtggtcaa
    60721 cattggttgt tttttcagtt aaatcatagc cgttcacagt gatgtgaccg ctagtgactt
    60781 cttctaaaag attgaggcta cggaggaaag ttgacttacc agaacctgaa ggaccgatga
    60841 tacaaacaac atctccttca tagaacttag tcgtaattcc ttttaggact tcattttttc
    60901 catagtgctt gtgtaaatca tttacatcaa tttttaattt tgccattaac gaatcctctt
    60961 ttctaagcgt ttcgctagtc tagtcaaaag tgtgataatt acaagataga agatagcaag
    61021 gattgcatac atcttgaaac tttggtagtt acgagcaatg ataatcttac cagtttggaa
    61081 gagttcaacc aaaccgatag cagatacgat agttgtatct ttaagagcga taacgaattg
    61141 gttgacaaag tttggcaaca tcaatttagt tgcttgtggc aagataatct tacgcatggt
    61201 ttttccataa gagataccca agcttcggct ggcttccatt tggccaactg gaacggcctg
    61261 aataccacca cgaacgattt cagcgatata agcagccgca ttgagtgaga gggcaatggt
    61321 tccagctaca aagtcgttaa ttgggctttg ttggcctgtg atagactcga tgaagtttgg
    61381 aattccccag aagatgaagg ctgcaagaat catcaatgga ataccacgaa taacgtcaac
    61441 gaaaatctca gagatgacgc gaagagattt gtatgggcta acgctaaaca taccgaagat
    61501 aattccgatg acaatggcaa tagcaaatga gataagagct agagcaagag tgataccaag
    61561 accgctaagg agttgtttgt agttgttttg aagcaagccc cagagcgttg tttcgtcaac
    61621 agtacttgtt gaagcagttg aagattcgct agctaggtat ttgtcaagaa tcttttggaa
    61681 ttcaccgttt gctttaaggt ttgcaagtcc gttgttgaac atttcaatca gttctggatt
    61741 tgctcctttt ttaacggcaa aggctgtttc accgattgga gttccagaga ttggagtttt
    61801 caatttttga ccttggctga tagaatattt gagaacaggt tcatcatcca taacggcatc
    61861 aatggcacca gtgtttaaac tgtcatacat tgaagaacca tcagcaaagg ttttgatttt
    61921 gtagccgtat ttgctttgat tttctgttag gaaggtttga gaagcagttc cgtttttaac
    61981 accgactgtc tttcctttta gatcttcata agaagcaata ttacttgatt ctttgacacc
    62041 aagaatggta ttagcagtgt agtatgattc tgagaagtca aaagttgcct tacgagcatc
    62101 tgtgacagac ataccagcga tgataccatc ggcttgacca gcttggacag cactgatagc
    62161 agcatcaaaa ccagggttgg tgatttcaat ttcaaaacct tggtctttag cgattgcctt
    62221 aatcaattcc atatcaatac cagtgtattg gttgcttgaa ttttggaaaa caaaaggggc
    62281 aaaagaagaa tcgctggcaa tgatatattt agccttaaca ggaatagctt ttaatcctgc
    62341 gagagtagtt gtagttggca ctgctgaaga tgatgaagca gtccatttct tgataatttt
    62401 atcaagacta ccatcttttt tcatttcaga caaggcttgg ttaaattcag taaccaggtg
    62461 ctcgtattta cttccttttt tcacaccgaa agcaaaactt cctacagctt caccatccat
    62521 ttcgatatgg aggtcttgac cttggttaat ggcatattcg ataacaggtt tgtcatccat
    62581 catggcatcg atggcaccag cactcaagct gttgttcatt aaatcaccag tgtcaaatgt
    62641 tttaatagta aagccatatt tatctttgat tgtttcaagg aaacgttgag cggcagttcc
    62701 gtttttaaca ccaacggttt tgccagttaa ttggtcgtac ttgctaattt tgtgtgactt
    62761 tgtagtagca atgacaactt ttgtatcata gtaagtatca gacatggtga agactttttc
    62821 acgttcttta gtctttgtca tccctgccat gatagcgtcg gcttgcccag cttgaaccgc
    62881 attgactgct gcgtcaaatc caggatagga catctgaatg ttccagcctt taatctcagc
    62941 gactttgtta ataatgtcaa catcaattcc tttataagtt tgatctgaat ctttaaactc
    63001 aaaaggtgca taggcggtat cagaaacaat cttaatcgtt tctgctttgg caatacctaa
    63061 tgagaaaatt gggaataaaa ttagcaaaaa tgctagaaat tttttcttca tttttagtct
    63121 ccttttccga atattctctc attatatcag aaaaagtaaa aaaaggcaaa ttgttatatt
    63181 tttcgtgtca gaaaatataa cattgatttt tccttttctt tcttgaattg ctattaaaaa
    63241 gtgctataat aatagtatat atagaagaaa agaggacggg gatatgaaga acaaaagaat
    63301 atttaaagac ttccaagctt caaaaatgag tttaaacatt tacacaagcc ccttgttagc
    63361 ctttgttttt gtcttcatag gagagtttgt ggcttttact ttgtatggta ttggcttgtt
    63421 agctctcatc ggacttgcta gaaattttgg agaggctggt caaaatcttg caacctactt
    63481 gcagaccttg catcagagct tgacggataa aacaagtgac tttcgtttaa ttttaggatt
    63541 actggccttt ggttttattc ttaacactgt gttcagatgg acaagaaaag ttgagaaaag
    63601 acctattcga accttgggat tttatagaga gaatttcctc agcaatcttc tgaaaggatt
    63661 tagtctaggc ctggcacttt ttcttctgac cttgttaggt ttagtggtct taggtcaata
    63721 tcgtttggaa tccattcact tgaatcctta ttctcttgcc tttgtcgtct ttactatccc
    63781 attttggatt ttacagggga cagcagaaga agtggtggcc cgtgcttggc tacttcctca
    63841 attggcctca agaaccaatc taaaactagc tattcttata tctagcctgt tctttaccct
    63901 gcttcatatg ggcaattctg gcctcacccc tctatctcta gtaaatctct ttttattcgg
    63961 agttgccatg gctctttacc ttctcaaaac tgatacagtt tggggtgttg caggtattca
    64021 tggtgcttgg aattttgctc agggtaatct ctttgggatt ttagttagtg gtcaaccgtc
    64081 aggaacgtct ctgatgacct ttttaccaca aggcaatcaa gattggctat caggtggttc
    64141 ttttggtatt gagggttcca tcgtgtccag tattattttg tttctgctga ttctttatct
    64201 cgcttaccaa ttaaagaaag aaaatgaaag gatgtgactt cggttcgtcc ttttcttcgt
    64261 gaaaatgata caagtatgct aaaataggaa tagcacatgg agagaggatt cttatgatta
    64321 accgcattac agataatcaa tttaaactag tatcaaaata tcaaccatca ggagatcaac
    64381 cccaagctat cgagcagttg gtagataata tcgagggtgg agaaaaagct cagattctga
    64441 tgggggcgac cggaacaggg aagacctata ccatgagtca ggtcatttcc aaagtcaata
    64501 aacccactct agtcattgcc cacaataaaa ctctggctgg tcagctctat ggggagttca
    64561 aggaattttt ccctgaaaat gcagttgagt acttcgtatc ctactatgac tattaccagc
    64621 cagaagccta tgtcccttct agtgatacct atattgagaa ggatagttct gtcaatgacg
    64681 agattgacaa gcttcgtcac tcagcgactt cagccctatt ggagcgcaat gatgttattg
    64741 tcgtggcctc ggtctcttgt atctatggtc tgggttcgcc caaggaatac gctgatagtg
    64801 tcgttagtct ccgtccaggt cttgaaattt cccgtgataa actcttgaat gacttggtgg
    64861 atatccaatt tgagcgaaat gatattgatt tccaacgggg aagatttcgc gttcgtgggg
    64921 atgtggtgga gattttccct gcttcccgtg atgaacacgc ttttcgagta gaattttttg
    64981 gagacgaaat tgaccgtatt cgtgaggttg aggctctgac aggtcaggtg ttgggagaag
    65041 tggatcattt ggctattttc ccagctactc actttgtgac caatgatgac cacatggaag
    65101 ttgctattgc taagattcag actgagttgg aagagcaact agctgtcttt gataaggaag
    65161 gtaaattgct agaagcccag cgattgaaac agcggacaga atatgatatc gaaatgctgc
    65221 gcgagatggg ctatacaaat ggggttgaaa actattcacg tcacatggat ggacgtagcg
    65281 aaggtgagcc tccttatacc cttctcgact tcttcccaga tgatttctta atcatgattg
    65341 acgagagcca catgactatg gggcaaatca agggaatgta caatggagac cgctctcgta
    65401 aggaaatgct ggttaattat ggtttccgtt tgccgtctgc tttggacaat cgtcctctcc
    65461 gtcgggagga gtttgagagt cacgttcatc agattgttta cgtttcagcg acacctggtg
    65521 actatgaaaa tgaacagacc gagacagtga ttgagcaaat cattcgtcca acgggactct
    65581 tggatccaga ggtggaagtc cgtccgacta tgggacagat tgatgacctc ttgggtgaaa
    65641 tcaatgcccg cgttgaaaaa aatgagcgta cctttatcac aactttgacc aagaaaatgg
    65701 cagaggactt gaccgactac ttcaaggaaa tgggtatcaa ggttaagtac atgcactcgg
    65761 atatcaagac cttggaacgg acggagatta tccgtgacct gcgcttgggt gtctttgatg
    65821 tcttggtcgg aattaacctg ctccgtgaag gaattgacgt tcctgaagtg agcctcgtag
    65881 ctattctcga tgctgacaag gaaggtttcc ttcgcaacga acgtggactc atccagacta
    65941 ttggacgtgc tgctcgtaac agtgaaggcc atgtcatcat gtatgcagac acggttaccc
    66001 agtctatgca acgtgctatc gatgaaactg cccgccgtcg gaaaattcag atggcctata
    66061 atgaagagca tggtatcgta ccacagacaa tcaagaaaga aatccgtgac ctgattgctg
    66121 tgaccaaggc agttgctaag gaagaggaca aggaagtcga catcaatagc ctcaacaaac
    66181 aagagcgcaa agaactcgtc aagaaactag aaaaacaaat gcaagaagcc gtcgaagtgc
    66241 ttgactttga actggcggct cagatccgtg atatgatgtt ggaagtcaag gccttggatt
    66301 aggggaatag tatgatttat ttaagaaagt taaagagaga agatttgatg tctttatggg
    66361 aaatggctta ttcacaactt aatccagttt ggaaacagta tgatgctccc tattatgatg
    66421 attatcagta tttttcaaat tttaaagaat tcgaactaca aaaatcagaa tccattttaa
    66481 gcaactcaaa tcgccttggt atttttgttg atgataaact agttgggact gtttcgcgtt
    66541 attgggtatg taaacaaaca agatggatgg aattgggaat tggtatttat gataaaaaat
    66601 tctggaacac tggtattggg aaagttgcta tgttgcagtg gatagatagg acgtttcagg
    66661 attacttgga gttggagcat ctgggtttga caacttggtc agggaatctt ggtatgatga
    66721 aacttgctga aaaattaaga atgaaaaaag aagctcatat tccaaaagtt cgttattatc
    66781 aaggtaaata ttttgatagt attaaatatg gtattttgag agaagactgg gagaaaataa
    66841 atgacggtta ttatcaaatc aatggaaact cctgaagaga tagaaggtaa atccttcgtt
    66901 cactggcaaa cgtggagaga ggcttatgac gaccttttac ctacagaatt tcaggagacg
    66961 atgacattag aaaggtgtcg actctttagt caaaagtatc cagaaaatac attgattgcg
    67021 atggatggtg tgaaggtagt tggttttatc agttatggta actttcgtga tgagactatt
    67081 caagctggtg aaattattgc tttatatgtt ttaaaagact attatggaaa aggtatcgca
    67141 caaaagttaa tgaaagcagc tttgattgct cttgatcatt tttctaaaat tttcttatgg
    67201 gtattgaaag ataataagcg cgccattgct ttctatcaaa aaatgggttt tacttttgat
    67261 ggtcaagaaa agatgcttga acttggaaag cctataaagg aaaaacgaat ggtattctat
    67321 tctaaataat tttaaaaagt agaagataat ggtactggta ccaattctga aaatgtaata
    67381 aattagaaag tgagtaaatt tatgtcccgt tcccaattaa cgattttaac aaacatttgt
    67441 ctaatagaag acctcgaaac ccagcgcgtg gtgatgcagt atcgctctcc tgaaaccaat
    67501 cgctggtctg gttatgcttt tccaggaggc catgtagaaa atggcgagtc tttcgcagag
    67561 tctgtcattc gtgaaatcta tgaagaaaca ggattgacta tccaaaatcc tcaacttgtc
    67621 ggcattaaaa attggccact agatacaggt gggcgctata ttgtcatttg ttataaagcg
    67681 actgagttct atggtactct tcgctcttca gatgaaggag aagtttcttg ggtgcaaaaa
    67741 gaccagattc caaacttgga tctggcttat gatatgctac ctttgatgga gatgatggaa
    67801 gctccggaca agtctgaatt tttctaccct cgccgtacag aagacgattg ggaaaagaaa
    67861 atcttctagt cttttactaa ataaccaagt ttatccaagg cctcctcgat atagtggagg
    67921 tcttgttgtg tttcggcttc gactaggtgg taatggatgc catctgtcaa ttcagataga
    67981 ggtctaaagt cagaatgctc gacttgttct agaaaatgtt gcacatctct gcgacaagac
    68041 agtttaagca aggtttcaat ttctccataa acgggatggt caatcaaggt attctggaca
    68101 tgcccaccat tatcgacaat agcaaggagt tcctgaccga tttcttcaac ttcatgtttc
    68161 actttgaaaa gtttgtgaac ataaggattg gtatcaattt gcttatagat gtagccacga
    68221 ttggtggata ggataggagc gccatcggct ctcaaaattg caatgtcctg cacaatgacc
    68281 tgacgtgtga catgaaaatg ttccgccaaa ctttggccat taagggcttt aggagcttct
    68341 ttcaagagtt ggagcagggc ttgtttgcga tcttttgtca tagcttttcc ttttaacggc
    68401 gttttcgaag cactttatag acagctagtg ctaatgtata gtctaccata ctatggataa
    68461 ttgtgccaaa tccaactagt acaaatagaa catagaacat gttttctaca ttggtacccg
    68521 aagttgcgta aaaaaggaca caggctaata cttcagcaag ggcatgaaca acagccaaaa
    68581 caaaattgaa aacccaggaa gattttggtt tatctagggt atcggggaat ttttgtaggt
    68641 aaagagctcc taaagcacca aaagatatat gggaaaaggc ccgaaaaacg ataaccatgg
    68701 gatagccagc catcaaaaat ccaaaactag aggctaggat gacaaaaact gccatcaagg
    68761 gcgacaagaa catggctata aaaatagcga tgtggctccc caaagtatag gaagcaggtg
    68821 gaatgacaat cttgaaaggc ataacaattg gaatcaaaat cgcaatagtc gttaaaaggg
    68881 ctgtcattgt cataaattgt gtctttttcc gtgtattcac aagaatctcc tttttaactg
    68941 catatacact agtatggtac aataaaccag acaataaagc aagaatttac ttgggtttat
    69001 agatcatttt ttagttaaaa gttatagtgg attgaaacta gaatagtaca cctctacttc
    69061 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt cttatttcgt
    69121 tttactatag taaagatttc attaaaaaga aactgtatag agcaaaatct ccaccttcag
    69181 gtttgaaagc ggagattgtt tttatttttt caaggtttgt agtcgtggaa caatggctag
    69241 ggatagaatt gcagaaatga ccaattcagc aattgaattt gttgagataa cggttgccag
    69301 aagaagttgg atatttccat tataaacatt tccaaatagg aagaagattc ctccaaggac
    69361 aaagatagta tttgtcaagg aaccaagggc cccagctaaa atcagaccag tcttgttttt
    69421 catcagttta tagactaagt aaggagttaa accaatcaaa atacgtggga caatggcaat
    69481 gatagctgag tagatgtttc cgtttggtac gaagggagag aagaggtagc ttgtcggtag
    69541 aatcgtaatc gtgttaaccg tcaagctaag taatcccatc aaaaatccaa gtgtaacccc
    69601 aactcgtgga ccataaataa tgctggcaat aatgacagga atatgaacaa tggtcggttt
    69661 gattggaaat ggaaaaaggt taaagataag tgagctcaga aagtgtatca cgagcatggt
    69721 agcaaaaaag atagcaatgg gtgcaatatt agagcgtttt ttcatcgata gtttccttta
    69781 ttctttctaa aataattgtg aggtcagcta aagctcctcg tccgtggtct ccacaagcta
    69841 gtagggattc cttaggagca atcagctgat agccgtaggt ttctaatgtt ttcagattat
    69901 tctgagttac tggatggtca tacatttttg tattcatagc aggagctatt agtttgggaa
    69961 tatgacttgg tagggctaga gctgtactgg ttaccatgtt gtccgcaaag ccgtgagcta
    70021 gttttgcaat agtgttagca gttgcaggta ccacgataaa taaatctgct ttttttccaa
    70081 gttcgatatg attgacctga tcaggatagg gttccttcat gacatccaag tggacaggat
    70141 tctgtgagag tacctgtagt gacaaaggtt ggataaactc tgtagcagcc tgagtcatta
    70201 agacagtgac ttgatggcct tgttttttta gagaactgac taaatctgcc gacttataag
    70261 aggcgattga acccgttaca gccaagagaa tgtttgccat agttttcctt tctaagaatg
    70321 ataggcttga attttttcaa ggaggagttc tgcaatttct tctttagtct ggactgtttg
    70381 aagctgattt ttctcaacaa atatagctcg gtgctgatct gctgaaattt gagtcaggtc
    70441 attcgcgatg attaaatctg cttgattctt gataagactt tttcgtgcaa tatcaaccag
    70501 atgatcttcg gtaacatcaa ccagcagttt gaaaccaatc agatgaatag taggattcca
    70561 ttccttgact agggatatga ttttgggtgt ctttttaagg aacaaaacct gaacctcatc
    70621 agttgaagaa atcttggcct gatgattctg cttgcttaaa aattctttta gattggagct
    70681 agcctgaact tcctcaagcc ctgtcatata aacaggagtg tagtcagaaa cagccattga
    70741 gtggatcaag atctgataat cctgaacacg ttcttgcatt tctattagaa ggtccttggt
    70801 attggtaatt tctcgaatac ttaggttagg atgagactct ggcttcagag ctcgttttgt
    70861 cgtaattaaa caaacttcat gccctgcaga aagcaaagtc tctgtgataa ttttccccaa
    70921 gtgacctgta gaatggttag tgatagagcg gacgctatcg atagcttcac tggtaccgcc
    70981 cgatgtaact aaaattttca tagcactatt gtacacaaaa ataagcggta agtaaaatga
    71041 aagtgataaa tttttggtaa aaacgaagat ttattatagt ttcaaactat aaagccatat
    71101 aaaatttaag aaaggactct aaaagtctta aaaacagaga tatttacgaa cgtttagaga
    71161 gttttaggat gttaaaaatc ttgttttgtg atataatgaa ttatcatata agaggttaga
    71221 ggaattttga atgaaaacag atattgaaat cgcacagagt attgagttga agccaattgt
    71281 tgatgttgta gagaaacttg gtatttctta cgacgatttg gagttgtacg gaaagtacaa
    71341 ggctaaactc agctttgata aaattcgggc agttgagagc aatccagtcg gtaaattgat
    71401 cttggttact gccatcaacc caacacctgc aggtgaagga aagtcgacgc ttaccattgg
    71461 tcttgcggat gccttgaaca agattggcaa gaaaaccatg attgctatcc gcgaaccgtc
    71521 tcttggtcca gtcatgggga tcaagggtgg tgctgctggt ggtgggtatg cacaagttct
    71581 gccaatggaa gacatcaacc tccactttac tggagatatg catgctatta caactgccaa
    71641 caatgccctt tctgccttga ttgacaacca cttgcaccaa gggaatgagc tgggaattga
    71701 tcaacgtcgt atcctctgga aacgcgttgt ggacttgaac gaccgtgcgc tccgccatgt
    71761 gactgttggt cttggtggtc ctctaaacgg tattccacgt gaggacggtt ttgatattac
    71821 agttgcttca gaaatcatgg caattctttg cttggcaacg gacatcgagg acttgaaact
    71881 tcgtttggcg aatatcgtta ttggttatcg ctatgaccgt acgcctgttt ctgtaggtga
    71941 tttgcaggtt gagggtgcct tggctttgat tttgaaggat gctattaagc caaacttggt
    72001 tcagacaatt tacggtacac ctgcctttgt acacggtggt ccatttgcca atatcgctca
    72061 tggctgtaac tctgttttgg cgacgacaac agcccttcac ttggctgatt acactgttac
    72121 tgaagctggt tttggtgcgg accttggtgc tgagaaattc cttgatatca agacaccaaa
    72181 cttgccaaca tctccagatg cagttgttat tgtcgcaacc cttcgtgccc ttaagatgaa
    72241 tggtggtgtg gctaaagacg ctctgactga agaaaatgta gaggcagttc gtgcaggttt
    72301 tgctaacttg aaacgccacg ttgaaaatat ccgtaagttc ggtattccag cagttgtagc
    72361 tattaacgaa tttgtatctg atacagaagc tgaaattgca gccttaaaag aactctgtgc
    72421 ctcaatcgat gtaccagttg aattggctag tgtctgggct gatggagcag aaggtggagt
    72481 agcacttgcc gaaacagttg ttaagacaat tgctgaaaat ccagctaact ataaacgttt
    72541 gtatgataat gacctttctg tccaagaaaa gattgaaaaa attgtcactg aaatctatcg
    72601 tggtagcaaa gtgaactttg agaagaaagc tcaaacacaa attgctcaaa tcgttcaaaa
    72661 cggttgggac aaattgccaa tctgtatggc taaaactcaa tacagtttct cagacaatcc
    72721 aaatgcgctt ggagcaccag aaaactttga aattaccatt cgtgaattgg taccaaaatt
    72781 aggtgcaggc ttcatcgttg ccttaactgg tgatgttatg accatgccag gtcttccaaa
    72841 acgtccagca gctctcaaca tggatgttga aagcgatgga actgtactag gcttgttcta
    72901 gtggattgaa attgacttta agtgagtttg gaaataatat ccaagctcat tttttctcag
    72961 actgcaagca gttcatcaat aagatttata ctcttcgaaa atctcttcaa actacgtcag
    73021 cttcaccttg ccgtaggtat atgatactga ctctgtcagt tctatccaca acctcaaaac
    73081 agtgttttga gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtata
    73141 agtagataga aaagttatat actatctatt gaaaatatta taaatcagat acaaagacag
    73201 gtgaaacctt ctgtgttata ctagagatat gttagatttg aaagaatacg gtatcgtcat
    73261 gtggccggag gagaaagtca tttctttccg tgagaaactt ctcgcttggt atgatgaaaa
    73321 caaaagagat ttgccttgga ggagaagtaa aaatccttat cacatctggg tatctgaaat
    73381 catgcttcag cagaccaggg tggatacagt tatcccttac tacgaaagat ttttggactg
    73441 gtttccaact gtcgaaagtc tggcaactgc gcctgaggag agtttactga aagcttggga
    73501 gggcttgggt tattattctc gagttcgcaa tatgcaggct gcagcccagc agattatgac
    73561 tgactttggt ggccaatttc caaataccta tgaaggaatt tccggcttga aagggattgg
    73621 accttacaca gcaggagcca tttccagtat tgcttttaac ttgcctgagc cagctgtaga
    73681 tggtaatgtc atgcgggtct tggcgcgtct gtttgaagtc aaccacgata ttgggattcc
    73741 aagtaatcga aaaatttttc aggcaatgat ggagatcttg attaatccag atcgtccggg
    73801 tgattttaat caagccttga tggacttagg gtctgatatt gagtctcctg taaatcccag
    73861 acctgaagaa agcccagtca aggactttag tgcggcatat cagaatggaa ccatggaccg
    73921 ttatccaatt aaatctccta agaaaaagcc ggttcctatt tatcttaaag ccttagttgt
    73981 gaaaaattct caaggacaat ttttacttga aaaaaatgaa agcgaaaagc tcttggcagg
    74041 tttttggcat ttccccttta tagaagttga taacttttcg caagaagagc agtttgacct
    74101 ctttcatcag gttgcggaag aaagtgtgaa ctctggcccc agtccagaag agagtttcca
    74161 gcaggactat gacctagatg ttgattggct tgatgtttgt tttgatacag tccagcatgt
    74221 ttttagtcat cgaaaatggc atgtacagat tgtagcaggt caggtgagtg acttccatga
    74281 tttttcagat agggaagttc gttggctttc accagaagaa ttcaagaatt acccacttgc
    74341 caaaccccaa caaaaaatct ggcaggctta tgcacaagcc aacttagaca gtagccaaga
    74401 ctagctattg tgtcttctga ctattttttg gtataatagt agagaaaaag gtgaacatat
    74461 gaaaaaaata ctaattgtag atgatgagaa accaatctcg gatattatca agtttaatat
    74521 gaccaaggaa ggttacgagg ttgtaactgc ttttaatggt cgtgaagcgc tagagcaatt
    74581 tgaagcagag caaccagata ttattattct ggatttgatg cttccagaaa ttgatggttt
    74641 agaagttgct aagaccattc gtaagacaag cagtgtgccc attcttatgc tttcagccaa
    74701 agatagtgaa tttgataagg ttatcggttt ggaacttggg gcagatgact atgtaacgaa
    74761 acccttctcc aatcgtgagt tgcaggcgcg tgttaaagct cttctgcgtc gttctcaacc
    74821 tatgccagta gatgggcagg aagcagatag taaacctcaa cctatccaaa ttggggattt
    74881 agaaattgtt ccagacgcct acgtggctaa aaaatatggc gaagaactag acttaaccca
    74941 tcgtgaattt gagcttttgt atcatttagc atcgcataca ggtcaagtca tcacgcgcga
    75001 acacttgctt gagactgtct ggggttatga ctattttggt gatgtccgta cagttgatgt
    75061 gactgtacga cgtctgcgtg agaagattga agatacgccc agccgaccag agtatatctt
    75121 gacgcgccgt ggtgtagggt attacatgag aaataatgct tgatttactg aaacaaacca
    75181 tttttaccag agattttatc tttatcctga ttttgttagg tttcatcctt gttgtgaccc
    75241 tcttattact ggaaaataga cgtgataata ttcagttgaa gcaaatcaat caaaaggtta
    75301 aagatttgat tgcaggagat tattccaagg ttcttgatat gcaaggtggg tctgaaatca
    75361 ccaatattac caataatttg aatgacttgt cggaggttat tcgtctcact caggaaaatc
    75421 tagaacaaga gagtaagagg ctaaatagta ttctgtttta tatgacagat ggggttcttg
    75481 cgaccaaccg tcggggtcag attatcatga ttaacgatac agccaagaag caactggggt
    75541 tggttaagga agatgttctg aatagaagca ttttggaatt gctcaagata gaagaaaact
    75601 atgaattgcg tgatttgatt acccaaagtc cagaattgtt gctagattcc caagatatca
    75661 atggcgaata tttgaacctt cgagttcgct ttgccttgat acgtcgagag tctggcttta
    75721 tttcaggttt ggtggctgtt ttgcatgata cgacggagca ggagaaggaa gaacgagaac
    75781 gaagactctt tgtttccaat gttagccatg agttacggac tcctctgact agcgtaaaat
    75841 cctatcttga agccttggat gagggggctt tgtgtgaaac tgtagcacca gactttatca
    75901 aggtttctct tgatgagacc aaccgtatga tgcgcatggt gacggatctc ctccatcttt
    75961 cacgtattga taatgctacc agtctcctag atgtggaact gattaacttc actgctttta
    76021 ttacctttat cctcaatcgt tttgacaaga tgaaaggaca ggaaaaggag aaaaaatatg
    76081 agttggtgag agattatccc atcaattcta tctggatgga aattgataca gataagatga
    76141 cgcaggttgt cgacaatatt ttaaataatg ctattaagta ttcgccagat gggggtaaaa
    76201 tcactgtcag aatgaagaca actgaagacc agatgatttt atccatttct gaccacggtt
    76261 tggggattcc taagcaggat ttaccacgta tctttgaccg tttctatcgt gtggatcgtg
    76321 ctagaagtcg tgcacaaggt ggtacaggtc taggactgtc tatcgctaaa gaaattatca
    76381 aacaacataa gggctttatt tgggccaaga gtgaatacgg caagggttca acctttacca
    76441 ttgtgctccc ttatgataag gatgcagtga aagaagaagt atgggaggat gaagtagaag
    76501 actagaatga gtgaaatagg ctttaaatac agtattttag cgtcgggttc cagtggaaat
    76561 tctttttatc tggaaacctc aaaaaagaag cttttagtag atgcaggctt gtctggcaag
    76621 aaaattacca gtctgctagc tgaaattaac cgtaagccag aagacctgga tgccatcttg
    76681 attacccatg agcattcaga tcatatccat ggagtaggcg ttttggctcg caagtatggt
    76741 atggatcttt atgccaatga aaagacctgg caagctatgg aaaatagtaa atatcttggc
    76801 aaggtggatt cttcgcaaaa gcatattttt gaaatgggta aaaccaaaac ctttggagat
    76861 atcgacatcg agagttttgg tgtaagccat gatgcagtcg caccgcagtt ctatcgcttt
    76921 atgaaggatg ataagagttt tgtccttttg acagatacag gttatgtcag tgaccgtatg
    76981 gcgggcattg tcgaaaatgc ggatggctat cttatcgagg ccaaccatga tgtagagatt
    77041 ttgcgatcag gttcttacgc ttggcgactc aaacaacgaa tcctatctga ccttggtcac
    77101 ctttctaacg aggacggtgc tgaagctatg attcggacgc taggaaatcg tactaagaag
    77161 atttaccttg ggcatttatc taaggaaaac aatatcaagg aactggctca tatgaccatg
    77221 gtcaatcagc tggctcaagc tgatctggga gtcggagtag actttaaggt ttatgatacc
    77281 tcaccagata ccgcaacacc attgacagag atatagaaag aacgctgaga aggtgttctt
    77341 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
    77401 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
    77461 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
    77521 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
    77581 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttggag
    77641 gatgaataat ttgtataaat tagttccgac aagacgattc atcaagcaat tgaaaaaatt
    77701 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tgaaagcccc
    77761 aagacaacac ggaaaggttt tggttggtaa tcgcgttggt caatggcgct atagaattgg
    77821 caattatcga gttatcgtac aaattgtaga tgatgaatta gtcgttgcta ttctagaagt
    77881 tggtcatcgg agagatattt attaaattaa agctgagtaa taacagtata gaaagtaagg
    77941 agagtaaaaa tttgaagaaa aaatggtttt ttgcagatta ttatgacaca acaattattt
    78001 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
    78061 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
    78121 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
    78181 tattgactat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
    78241 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
    78301 caggtaaatt agaaagaaaa attagtagat tcttacggac aaatggcctg atttatatct
    78361 tatatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
    78421 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
    78481 atattgttcc agtttccctt tttgggaaat ggctagcagt tttactgatg cttgtcggta
    78541 ttggaacaat agggatgcta acaagtgctt tgacgaactt ttttgtaaag gataatccag
    78601 atgaacagat aaaacttgat aaactcaaag acgaattatc gagccaaaga atattaatag
    78661 agaaacaatc tgaaaaaatc gaagaactac atcgaatgat aaaagactta gttgaaaaaa
    78721 tatcataaag gtgagacaaa acaaaacttg attcgaggag aaatcaagta agttttgaca
    78781 caatagaacg catattatca ggtataaaaa tttgataata tgcattttat agagaaatga
    78841 aataaaattt gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
    78901 atggggtgct atttcaactt caacctacta taatacagaa agaaacaact ccctgatgat
    78961 tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc tggatttttc
    79021 catgcttcgt caataatagc ttgcaattct ttagcagatg cttgcatttt ttgagtttct
    79081 gcatcgttca atggaatgtt tactggacga acgataccat gtgcaccaac aacagctggt
    79141 tgaccgataa agacattctc aactccgtat tgaccttctt ggaatactga aagtggaagt
    79201 actgcgtttt catcgtcaag gattgcttta gtgatacgag caagggctac tgcgataccg
    79261 tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac accttcgaac
    79321 aattcaatca attcagcttc ttgaacattt tgagtgtctt taaggaattc ttcaaggttt
    79381 acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg ttcacccatg
    79441 atgtaggcgt gcactgaacg agcatccaca tccaattttt cagcaagtgc ttgacggaaa
    79501 cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa accagagaat
    79561 ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa gatacctttg
    79621 aaaccagatt caacaacttg agttacgatt gatttgttga tagcaaggtt tttacctaca
    79681 aggtcaagac gagtttcacc tggtttttga ggtgcacctg cagtgatcac aacaaggtca
    79741 gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt gaaggcaagg
    79801 gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg aatttcgata
    79861 attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga tgaacctaca
    79921 gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat tgttttaaac
    79981 atctccttaa ttttattagg ggattttccc tagacaactt cattctatca cttttaaaaa
    80041 actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt ttagaggctg
    80101 aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat gaggcattta
    80161 ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa ggcaagtttt
    80221 atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg agatggctta
    80281 aaacctgttc accgtcgcat tctctacgga atgaatgaat tgggtgtgac cccagacaaa
    80341 ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca cccacacggg
    80401 gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta ccgttacatg
    80461 cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc cgctcaacgt
    80521 tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat caacaaaaat
    80581 acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt cttgccagcg
    80641 cgttttccaa accttttggt taatggagca actggtatcg cggttgggat ggcaaccaat
    80701 attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat ggataatcct
    80761 gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc aactggtgct
    80821 cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg ttcgattgtc
    80881 ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgtat cgttgtaaca
    80941 gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg cttggttcag
    81001 gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga aggtgttcga
    81061 tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa cctcttcaaa
    81121 atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa tggtataccg
    81181 aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa agaagtggtt
    81241 gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat cttagaaggt
    81301 ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc tagtgaaacg
    81361 gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg tcaaagtcaa
    81421 gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa gattcaatct
    81481 gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc taagcctgaa
    81541 cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt ttctgataag
    81601 cgccgtacag agttgatgat tggacaggtc ttgagtctcg aggatgagga cttgattgaa
    81661 gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt ggatcaggac
    81721 gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt gaaagatgat
    81781 gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt cttcacaaac
    81841 aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg gactgccaaa
    81901 gggctaccag tagtcaatct cttgaaattg gatgaagacg aaagtattca gacggttatc
    81961 aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg tcacggtatt
    82021 gtgaagagaa ccagtgttaa ggagtttgcc aatattcgtc aaaatggtct caaagcgctg
    82081 aatttaaagg atgaagatga gttaatcaat gtcttgttgg cagaaggaga tatggatatt
    82141 atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt tcgtggtatg
    82201 agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac agttgttggt
    82261 gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg atatggtaag
    82321 cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat gcagacagct
    82381 aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg ggatgaggat
    82441 ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa tatttcacaa
    82501 acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc tcagatagtg
    82561 actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa cgaaacagaa
    82621 ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa aatctgctga
    82681 caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt aatactcaaa
    82741 ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag gtatcaaaag
    82801 aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct gtcaaagcta
    82861 tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca gttattgggg
    82921 gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt gataatgtta
    82981 atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa ggaaattata
    83041 gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta ttttctcctt
    83101 tagataatgc taaaaatggc atgaagattt atctaaccga taaaaataaa gtttatactt
    83161 atgaaatacg tgaagtcaaa cgtgtgacac cggatcgtgt tgatgaagtt gatgatagag
    83221 atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca gaacgtatta
    83281 ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat gaaatcctaa
    83341 cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa tcatggattt
    83401 cactgatttt ttaagatttt cataaaaata tagtaaaatg aaataagaat aggacgaatc
    83461 gttcaggaca gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag
    83521 tttcaatcta ctataaactt ttatgaaata cagaaaacgc ttcctaaaac ctaaagtttg
    83581 tgatataatt atcaagaaaa agatttagga gtttattatg gtttcttcag aatttatctc
    83641 aaagattgaa tttgcttgca ataagaaaga aagtctttat agtcaaagca aatttaagta
    83701 tgcgattcgt tcgatgttcg caggtgcatt tttaaccttc agtactgctg caggtgcagt
    83761 tggggctgac ttgattaata aaattgcacc aggtagtgga cgcttcctct ttccattcgt
    83821 ttttgcttgg ggcttggtct acattgtttt tttgaatgcc gagttggtca cttcaaacat
    83881 gatgttcttg actgctggta gtttcttaaa aaaaatctct tggagaaaaa cagctgagat
    83941 tttactatac tgtaccttgt tcaaccttat cggagccttg atagcagggt ggggctttgc
    84001 tcattcggca gcctatgcga atctgacaca cgatagtttc atctcaggtg ttgtagagat
    84061 gaagttaggt cgttccaatg agttagtctt acttgaaggt attttagcca atatctttgt
    84121 aaacattgcc attctttcat ttgttttggt caaagatggt ggtgccaaac tttggcttgt
    84181 gttgtcagct atttacatgt ttgtattctt aacaaacgag cacattgcgg cgaactttgc
    84241 ttctttcgcg attgtgaaat tcagtgttgc tgcggattca attgccaact tcggtgttgg
    84301 aaatatgctt cgccactggg gtgtgacttt catcggaaac tttatcggag gaggcctctt
    84361 gatgggtctt ccatatgcct tcctcaataa aaacgaagat acttatgtag attaagaaaa
    84421 tgagcacgat tgagtcgtgc ttttttcatt ttcaaaataa ggtaatagct atttcttata
    84481 tcaaaatata gaaaactgat atttgtaaac tataactcaa ggtgctacaa tatccttaat
    84541 aaaatgatat ggaggtcacc ttatgacttg tgattttaaa tctgaaactc tacaactaca
    84601 tgctggtcaa gttgtggctc cagctactaa gtctcgtgca gtgccgattt atcaaacaac
    84661 attttttgtt tttgatgaca cgtaggaagg tgccgatctg tttgccttga ggaaaccagg
    84721 gaacatttat actcgtatca ccaatcctac aacagctgcc cttgaaggtg gtgttgaagc
    84781 gctagcaaca gcatcaggta tgactgcagt gacttatacg attttggcgc ttgcccatgc
    84841 tggtgaccat gtagtggctg cttcgactat ttacggtgga accttcaatc ttttgaaaga
    84901 accccttcct cgttatggta tcacaacaac ctttgtcgat gttgataatt tggaggaagt
    84961 agaagcagct atcaaagaca ataccaagct tgtcttgatt gaaaccttgg gtaactcctt
    85021 gattaatatt ccagacctgg aaaaactggc agagattgct cataaacatc aaatcccact
    85081 tgtgtcagac aatacttttg caacacctta tttgattaac gtcttctctc atggcgttga
    85141 cattgccatt cactctgcga ctaagtttat cggtgggcat ggtacaacta ttggaggaat
    85201 aattgtcgat agtggtcgtt ttgactggac ggcttcaggg aaattccctc aatttgttga
    85261 cgagagtcca agctgccaca atttgagcta tactcatgat gtgggtgcag cagcctttat
    85321 tatagctgtt cgagttcaat tgcttcgtga tacaggtgca gccttgtcac cattcaatgc
    85381 tttcctcttg ctacaaagac ttgaaaccct ttcacttcgt gtggaacgcc atgtacaaaa
    85441 tgctgagaca attgttgatt ttcttgtcaa ccatcctaag gtagaaaagg taaattatcc
    85501 aaaacttgca gatagtcctt attatgcctt ggctgagaaa tacttgccaa aaggtgtcgg
    85561 ttcaatcttt accttccacg tcaaaggtga cgaggaggaa gcacgcaagg tcattgataa
    85621 tttagaaatc ttttctgacc ttgcaaacgc ggcagatgct aaatcgcttg ttgtccatcc
    85681 agcaacaatc actcacggtc aattgtcaga aaaagaccta gaagcagcag gtgtcacacc
    85741 aaatcaaatc cacttgtcta tcggtcttga aaatgtagaa gatttgattg aagacttacg
    85801 cttggccttg gaaaaaattt aaagtaaaag aagataaaca gtgggttttg actcactgtt
    85861 tttgattttc cctcaggcat gatataatgg ttacagaagt ctagaaagag gaatgtaatg
    85921 aacgaaatca aatgtcccaa ctgtggggaa gtctttacag taaatgaaag ccagtatgct
    85981 gaacttttgt cccaagtgag aacggcagag tttgataagg aactacacga taggatgagg
    86041 caggaactgg ccttggctga gcaaaaggct atgaatgagc aacagactaa actggctcag
    86101 aaggatcaag aaattgcgca attgcagagt caaatccaaa actttgatac agaaaaagaa
    86161 ttggccaaga aagaagttga acagacaagc catcaggcct tattggctaa ggacaaggaa
    86221 gtacaggcct tggaaaacca gttggcgacc ttgcgtttgg agcatgaaaa tcaattgcaa
    86281 aagacccttt ctgacctaga aaaagaacgc aatcaggtca aaaatcagct cctactgcaa
    86341 gaaaaggaaa atgagttgtc tttggcttct gttaagcaaa actacgaagc ccagctcaaa
    86401 gcagccagtg aacaagtcga gttttataag aattttaagg ctcaacaatc tacaaaagcg
    86461 attggggaaa gcctagaaca gtatgcagag agtgagttta acaaggttcg tagtttcgcc
    86521 tttccaaatg cttactttga gaaggataac aaggtctctt cgcgtgggtc taaaggggac
    86581 tttatcttcc gtgagtgtga tgaaaatgga gttgaaatca tttctatcat gtttgagatg
    86641 aaaaacgaag cggacggaac agagaagaag cacaagaatg cagattttta caaggaattg
    86701 gacaaggacc gtcgggagaa gaactgtgag tatgccgttt tggtgaccat gcttgaggct
    86761 gataatgact actttaacac agggattgtt gacgtcagtc acgagtatga aaaaatgtat
    86821 gttgttcgtc ctcaattctt tatccaattg attggtctct tacgtaatgc ggcgctaaat
    86881 tccctaaaat acaagcagga gttggccttg gttcgcgagc aaaatattga cattacgcat
    86941 tttgaggaag acttggatgc ctttaagcta gcttttgcta agaactataa ttcagcttcg
    87001 actaactttg gaaaagctat tgatgaaatc gacaaggcca tcaaacgcat ggaagaggtt
    87061 aagaaattcc tgactacatc tgaaaaccaa ctccgtctag ctaacaacaa attggaagat
    87121 gtctctgtta aaaaattgac ccggaaaaat ccaacaatga aagcgaagtt cgaagcactg
    87181 aagggggagt agaaagcaaa aatgaacggt attatcaact taaaaaaaga agcaggaatg
    87241 acctcgcatg atgcggtttt taaactgcgt aagattttgg gaaccaagaa aattggtcat
    87301 ggcggaacct tggatccgga tgtggtgggt gttttgccga ttgcggttgg caaggcgaca
    87361 cgcatggtcg agtttatgca ggacgagggt aagatctatg agggggaaat cactctgggt
    87421 tattccacga cgactgagga tgctagtggg gaagtggtcg cagaaacccc tgttttgtct
    87481 cccttggatg aaaagcttgt tgatgaagcg attgctagct tgactgggcc tattacccag
    87541 attcccccta tgtattcggc agttaaggtt aatggtcgca agctctatga gtatgcgcgt
    87601 gctggtcagg aagtggagcg tccagaacgt caggtgacca tttatcaatt tgagcgaaca
    87661 agtccgattt cttatgatgg ccaacttgcc cgattcactt ttcgtgtaaa atgcagtaaa
    87721 gggacttaca tccgtacttt gtcagttgat ttgggtgaaa agcttggtta tgcggctcat
    87781 atgtcccatt tgactcgtac tagtgctgct ggcttacaat tagaagacgc tcttgccttg
    87841 gaggaaattg ctgaaaaagt agaggctggg caattagatt ttctccatcc tttagagatt
    87901 gggacaggtg accttgtcaa agttttccta actccagaag aggctacaga agttcgcttt
    87961 ggtcgtttta ttgagctaga ccaaacggac aaagaactgg ctgcctttga agatgataaa
    88021 ttgttagcca ttctagaaaa acggggcaat ctctataagc caaggaaggt ttttagctag
    88081 atcgtttagg aataaaaatc gggtgataga taacaattgc ttgataaaac cccatactaa
    88141 tagtagaatg gttttgggaa ttataatatt ccaattgttg cgagttgtag gtactcaaat
    88201 aatctatata gaaatttaga ggtgtgaaat gaagcaattt aaaattcttt cagataaata
    88261 tttagagtcc attacaggtt ctggtgggaa cttaggccca ggatttggtg tgataattcc
    88321 atgatgcgaa atgagtttcg agaaagggtg gagcaacttc ttcaacaaaa agaaataaat
    88381 gaaaatagtg agttgagtca cctgtttcgt cttgctatac aaaatttaga cagaaatgaa
    88441 aaataccaat cggtcatggc caatttgagt caagggttgt cactttacct catgacgcat
    88501 cattaccagg cacctaagtc tgtcattgat tttggtttat ggattgccaa agctcctagc
    88561 caggaaagag ggagactggc tttcttgcag atgcttgctc aaaccctaca gggctttcgt
    88621 taaaactgtc gaacatcaga gggaagactc tggtgttttt tgctgatgag actataaatt
    88681 ttgtaaaaaa tgtgatagaa tagacgacgg ataaaataac ggaggatagc atgcaaaata
    88741 gaccaatcat tattggagtg acaggtggtt ctggtggtgg taaaaccagt gtttcaagag
    88801 ccattttatc gcattttcct gatgaaaaga tttccatgat tgagcatgat tcatactaca
    88861 aggatcagtc tcatttgacc tttgaagagc gtgtcaaaac caactatgac catccttttg
    88921 cctttgatac agacttgatg atcgagcaga ttaaggaatt gttggcaggg cgtccggtgg
    88981 acatcccgac ctacgactat acagagcata cacggagtag caagacctat cgtcaggagc
    89041 ctcaagatgt ctttatcgtt gagggcattt tggtcttgga ggacaagcgt ctgcgcgatt
    89101 tgatggatat caagattttt gtggatacgg atgacgatgt gcgcattatt cgtcgtatca
    89161 agcgtgatat ggaggagcgt ggccgtagcc ttgatagcgt tattaaccag tacttaggtg
    89221 tggtcaaacc aatgtaccac cagtttatcg agtcaactaa gcgttatgct gatatcgtca
    89281 ttcctgaagg ggttagcaat accgtggcta tcgacctgtt gacgaccaag attgcaaaga
    89341 ttttggaaga agctcgaaac agcaaataat cacatgtgga ggccttgcct cctttttcta
    89401 tttttccctc ataatggtac ataaatggag atttttaggc atatttttgg tataataata
    89461 cccatgaaag agcaagtaaa tgaatagtag gtggagatgg aaaagtattt atcggtaaca
    89521 actttgacca agtatctgaa aatgaaattc gataaagacc catacttgga acgggtctat
    89581 ttaactggtc aagtttccaa ctttcgtaaa cgacctactc accaatattt ctccctaagg
    89641 gatgaccatg cagttattca agcgaccatc tggtctggga tttatcagaa attagggttt
    89701 gacctggaag aaggaatgaa gatcaatgtg attgggcgtg tacaggtcta tgaaccaagt
    89761 ggtagctact ccatcatcat tgaaaaagct gagcctgatg gggttggggc gcttgcgatt
    89821 cagtttgaac aacttaagaa aaaattgaca gaagaaggcc tgtttcaaga acgcttcaag
    89881 caagctctac cccaattttc taagagaatt ggggtagtaa ccagccgtag tggagccgtt
    89941 attcgagata ttatcacgac cgtcagcagg cgattcccag gtgttgacat ccttctttat
    90001 ccgaccaagg ttcaaggtga aggggctgcg gaggaaattg ctagaaatat tgcgcgtgct
    90061 aatcaatggg acgatttgga tttgctcatt attggtcgtg gaggtggttc tattgaggat
    90121 ctctgggcct ttaacgaaga aattgtggta cgagctattt ttgaatctcg tttgccagtt
    90181 atctctagtg tggggcatga gacggatgtg accttggcag attttgtggc agatcgacgc
    90241 gctgcaacgc caacagcggc ggctgaactg gcaacacctg tgaccaagtt ggatgtatta
    90301 gctcatttgc aaaatcagga aaaacggatg gtaacggcag tccgaaatgt tctatctaag
    90361 aaacaagagg ctttgaaaaa atgcagtcag tctgttatct ttagacaacc tgagcgcttg
    90421 tatgacggtt atttgcaacg cttggaccaa ctgcaactgc gtttgaaaca aagtttgcga
    90481 actcggattt ctgataacaa acaattagtt caagcaagaa ctcatcaatt agtacaatta
    90541 tcacctgtta ccaaaatcca acgctatcaa gaccgtttag gacagttgga caagctctta
    90601 ggtagccaaa tggcgttagt ttatgacgcc aaggttgctg aggtcaagcg actttcggaa
    90661 gctttgctca tgttggatac tagccgaatc gtggcgcgtg gttatgctat tgtcaaaaaa
    90721 gaagagtccg ttgtagattc ggttgagagt ttgaagaaaa aagaccaagt aacgcttttg
    90781 atgcgagatg gtcaagtaga attagaggtt aaagatgtca aaacaaaaga aatttgagga
    90841 aaatctagca gaactggaaa ccattgtcca aagtttggaa aatggtgaaa ttgctctgga
    90901 agatgcgatt actgcctttc aaaagggcat ggtcttgtca aaagagctcc aagctacgct
    90961 ggacaaggct gaaaagacct tggtcaaggt catgcaagaa gacggaacag aaagtgattt
    91021 tgaatgaaaa agcaagaaaa attagctctt gtcgagtcgg ctttggaaga tttttatgga
    91081 gaccagcagt ttgcctctag tttacgggag tctgttctct attctattca tgctggtggc
    91141 aagcgtattc ggccttttct cttgttagaa gttctggaag ccttgcaggt taccatcaaa
    91201 cctgctcacg cgcaggtagc tactgccttg gagatgattc atacagggag cttgattcac
    91261 gatgaccttc ctgctatgga tgatgacgat tatcgaagag ggcggttaac caatcacaag
    91321 aaattcggtg aagctatggc cattttggct ggagatgcct tattcttaga ctcatatgcc
    91381 ttgattgcgc aggcagattt gccaagtcag attaaggtgg acttgattgc caacttatcc
    91441 cttgcttcag gtagtctggg tatggtggca gggcaagttt tggatatgga gggcgaacac
    91501 cagcacttgt ctttggaaga acttcagact attcatgcca ataagactgg gaagttacta
    91561 gcctatccct tccaagcggc agctattata gctgaattgt cacctgaaat gcaggtgaag
    91621 ctgaaaactg tgggtgaatt gattggactt gcttttcaag tcagagatga tgtactggat
    91681 gtgacagcta gttttgagga aatcggcaag acacctcaaa aggatctgca ggcagaaaaa
    91741 tcaacctatc ctgccctgtt gggcttggaa gagtccattg ccttttgtaa ccaaaccctg
    91801 gatcaagcta atgaaaaatt agaagaaatt gcccagcaga ttccctttga aacagaatcg
    91861 attgtaagtg tagtagaaag tttgagaatc aatggctaag gaaagagtgg atgtactagc
    91921 ttataaacag gggttgtttg aaacgagaga gcaggccaag cgaggtgtga tggctggcct
    91981 agtcgtagca gtccttaatg gagaacggtt tgacaagcca ggagagaaaa ttccagatga
    92041 caccgaatta aaactcaagg gggagaaact caagtatgtc agccgtggtg gtttgaaact
    92101 ggaaaaggcc ttgcaggtct ttgatttgtc ggtggatggc gcgactacga ttgatatcgg
    92161 ggcctctact ggaggtttta ccgatgtcat gctacagaat agtgccaagt tggtctttgc
    92221 agtcgatgtt ggtaccaatc agttggcttg gaaattacgc caagacccac gagttgtcag
    92281 tatggagcag ttcaatttcc gctatgctga aaagactgat ttcgagcagg agccgagctt
    92341 tgccagtatt gatgtgagtt tcatttccct tagtctgatt ttgccagcct tgcaccgtgt
    92401 cttggctgat caaggtcagg tggtagcact tgtcaaacct cagtttgagg caggacgtga
    92461 gcagattggg aaaaatggaa ttattcgaga tgctaaggtt catcagaatg tccttgaatc
    92521 tgtaacagct atggcagtag aggtaggttt ttcagtcctt ggcttggact tttctcccat
    92581 ccaaggtgga catggaaata ttgaattttt agcgtatttg aaaaaagaaa agtcagcaag
    92641 caatcagatt cttgctgaga ttaaagaagc agtagagagg gcgcatagtc aatttaaaaa
    92701 tgaataaaaa agagagactt gaaaaaatta gaagattggt gacagattat caaatcggca
    92761 cgcaagaaga aattgtagaa catttgaaag aagcaggtat cactgccact caggcgacgg
    92821 tatcccgaga tatcaaagag ttaggtattg tcaaaattcc tttgagagac aacacctatg
    92881 tctacgaatt gccaaaatca atcgtaaaaa gtctgcaact ggctgaagac aatatcgaat
    92941 cggctgaatt gatggataag atgatcaatc tccaagttat tccaggaaat acggcttttg
    93001 taaaagctca gttaatcgat acttttgcag acaagatttt tagttgtttg actgatgata
    93061 gctcgatttt agtcattgcc agaagtggaa gtctagtaga ggaaatcttt gaacaagtaa
    93121 aaaattggta ggtctatatg ttacttgaaa tttcgataaa aaactttgcc attattgagg
    93181 ctatttccct caattttgaa aaggggatga ctgtcctgac tggtgaaacg ggtgcaggga
    93241 agtcgattat cattgatgcc atgaatatga tgttgggagc tcgtgcgacg acagatgtta
    93301 ttcgtcatgg tgcaccaaag gcagagattg aggggctttt ctcagttgag aatagtcgtc
    93361 ttttacagga aatttttgat gagcaaggtt tagagttagg tgatgaaatt atcatccgtc
    93421 gggaaatctt gcaaaatggt cgtagtatca gccgtgtaaa tggtcagatg gttaatctgt
    93481 ctgttttgcg agctattggg caacatcttg tagatattca tggtcagcat gaccatgagg
    93541 agttaatgcg tccccaactg catatccaga tgttggatga atttggtgat gccgcttttt
    93601 gggacttgaa agaaacctat caaacgagtt ttgatgccta tcggaaaatg cgcaagcagg
    93661 ttctggaagt caagaaaaac caacaggaac acaaggcacg tatcgaaatg ttggaatttc
    93721 aaatggcaga gattgaggca gcaaacttgc aggctggaga agacttggat ctcaatcaag
    93781 agcgagataa actcctcaac cacaaaaata ttgcggatac actgaccaat gcctacagta
    93841 tgttggacaa tgaagatttt tcaagtctgg ccaatgttcg ttcagccatg aatgacatgg
    93901 aaagtgtcga agagtatgac cctgaatacc gtgaaatttc aagctctctg tctgagacct
    93961 actatgtttt agaagacatt agcaaacgtt tggaagctat cattgaggac cttgattttg
    94021 atggcaatcg cctcatgcag gttgagaatc gtttggacct ccttcatact attactcgta
    94081 agtatggtgg gactgttgat gatgttttgc tttattttgc caagattacg gaagaataca
    94141 atctcttgac aggcaataat ctttcgtctg aggacatgga agcagagctt aagaagttgg
    94201 aagtcaatct tgtcaatttg gcaggtcaac ttgcttctgc tcgtcataat ttggctcagc
    94261 aactcgaagc tgagattaaa caagaactgc aagatcttta tatggaaaaa gcccagtttc
    94321 aggttcgttt tagtaaggga aaattcagtc gtgagggaaa tgaaatggtt gagttttata
    94381 tttcaaccaa ccctggagaa gactttaaac ccttggttaa ggttgcttct ggaggggaat
    94441 tatctcgtct catgttagcc attaagtctg ccttttcacg taaagaaggc aagactagca
    94501 ttgtctttga tgaggtggat acgggagttt caggtcgtgt tgctcaagct attgctcaga
    94561 aaattcataa aattggtcag tatggtcagg ttttggctat ctcccatttg ccacaagtaa
    94621 ttgcgattgc agattatcaa ttctttattg agaagattag taatgaccat tcaacggttt
    94681 cgactgttcg tctcttgaca gtcgaagagc gagtggagga agttgccaag atgttggcag
    94741 gtgatgatgt gacagaagca gccctgacgc aagccagaga attgttgaga aacagggaga
    94801 aataagatga cagattatta tgtaattgga gatgttcacg gaaaagctgg gatgctggaa
    94861 gaccttctta aaacctggga tggtcagacc cagttgctct ttctaggtga tttgattgac
    94921 agaggtgagg atagtcaccg tgttcttgaa atggtcaagg acttggtgga caatcaaggg
    94981 gctatctgtt tgtctggaaa ccacgagtat atgtttttga cttggctaga ttacccagaa
    95041 gaaagttatg accattatcg tcgcaatggt ggagatacaa ccattaactc tatcctaggt
    95101 cgtcccttgg atgcaccagt tgatggagta gaagatgcca agcgggttgc cgctgaagcg
    95161 gcagacttgg tcgaattcat tcgtcaaatg ccatttgtag tagagacaga caagtatatc
    95221 tttgttcacg caggtattga tttgaccttg gacgactggc atgaaacaac agattataaa
    95281 aaagtatggc ttagaaaacc attccacgga gctgaaaatc atactggaaa aaccattgtc
    95341 ttcggtcata caccggtcta tggtttgtta cagcaagaac gcggtacatc tgagctttgg
    95401 actacagaag atggcaagat tggaatggat ggaggagctg tttatggtgg tgtccttcac
    95461 gggattgtct ttacagacca aggaatgaca gaacaccact ttatcgaaaa tgacggcttt
    95521 gtcgctgaag attagtactc ctagcagggt atggtcttgt caaaatatca aaaacaattt
    95581 ataataaata gataccctga aaggaagaga atcatgaact tagaagaatt gaaaaaacga
    95641 caggagaaga tccgtaactt ctctattatc gcccatattg accacggaaa atcaactcta
    95701 gcagaccgca ttttggaaaa aacagagacg gtttcaagtc gtgaaatgca ggcccagctt
    95761 ttggatagca tggatctaga gcgggaacgt ggaattacta ttaagttgaa tgccatcgag
    95821 ttgaattaca ctgcaaaaga tggggaaact tatattttcc acttgattga cacaccaggg
    95881 cacgttgact ttacctatga agtttcacgt tcgctagctg cctgtgaggg tgctattttg
    95941 gtggtcgatg cggctcaagg aattgaggct caaactcttg ccaacgttta tctagctttg
    96001 gataatgatt tggaaatcat gcctatcatt aataaaattg acctgccggc tgcagatccg
    96061 gagcgcgtgc gtacagagat tgaagatgtg attggtttgg atgccagtga agcagttttg
    96121 gcttctgcca aggctggtat tgggattgaa gaaatcctcg agcaaattgt agaaaaagta
    96181 ccagcaccaa cgggtgatgt gacggcgcca cttaaggcct tgattttcga ctctgtttac
    96241 gatgcttacc gtggggttat cctacaagtg cgtgtcatgg acggagtggt caaacctggt
    96301 gataagattc agctcatgag caatagtaag acctttgatg tggccgaagt cggtattttt
    96361 acaccaaaag cggttggtcg tgatttcctt gcgactggtg atgttggtta cattgcggcg
    96421 tctatcaaga cggttcagga tactcgtgtg ggtgataccg ttaccttggc aaccaatcct
    96481 gcggcagaac cattacatgg ttataagcag atgaatccta tggtctttgc gggtctctac
    96541 ccaatcgaat caaacaagta caatgacctg cgtgaagcgc ttgaaaaatt gcaactgaat
    96601 gatgctagtc ttcagtttga accagaaaca tctcaggcac ttggatttgg tttccgttgt
    96661 ggatttcttg gacttctcca tatggatgtt atccaggaac gtttagagcg tgagttcaat
    96721 attgacctca tcatgacagc tccgtctgtt atttacaaag ttaatttgac cgacggtgag
    96781 tctatggatg tgtctaaccc atctgagttt ccagacccaa ctaagattgc gaccattgaa
    96841 gagccttatg tcaaggcgca aatcatggta ccacaggagt tcgtcggagc agtaatggag
    96901 ctagctcagc gtaagcgtgg ggactttgtg actatggact atattgatga taaccgtgtc
    96961 aatgttatct atcaaattcc tcttgctgaa attgtctttg acttctttga taaacttaag
    97021 tcttcaacac gtggttatgc aagctttgac tacgaattgt cagaatatcg cccatctaag
    97081 ctggtgaaaa tggatatcct tctcaatgga gataaggtgg atgctctcag ctttatcgtt
    97141 cacaaggact ttgcctacga acgtgggaaa ctcatcgttg ataaactcaa gaaaatcatc
    97201 cctcgccaac aatttgaagt tccaatccaa gcggctattg gacacaagat tgtcgctcgt
    97261 actgatatca aggcccttcg taagaacgta cttgctaaat gttatggtgg tgacgtttct
    97321 cgtaagcgta aactccttga aaaacaaaaa gctggtaaga aacgcatgaa atccatcgga
    97381 tcagttgaag ttccgcaaga agccttcctc agcgtcttga gtatggatga agaataagtt
    97441 atcagaaatg cctttccttg ttcacaggaa atttatataa gaatcaatag taaagcaggc
    97501 ttagatggtc tgctttttta gtttttatac tcttcgaaaa tctcttcaaa ccacgtca
//
LOCUS       DAVDHC010000005        80522 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVDHC010000005 DAVDHC010000000
VERSION     DAVDHC010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80522
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.005"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            583..789
                     /locus_tag="VUR43_000488"
     CDS             583..789
                     /locus_tag="VUR43_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412223.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
     gene            786..980
                     /locus_tag="VUR43_000489"
     CDS             786..980
                     /locus_tag="VUR43_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412224.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFFVFLMGMEWLKGESHDGG"
     gene            967..1851
                     /locus_tag="VUR43_000490"
     CDS             967..1851
                     /locus_tag="VUR43_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412225.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEQSNLAENWVQKQDALQVVTREANAFWQLLVQAGCSIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            1853..2590
                     /locus_tag="VUR43_000491"
     CDS             1853..2590
                     /locus_tag="VUR43_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5412226.1"
                     /translation="MKRWIALNKIEFLLTKRQLVYYLLSVGMPTAFYLFFSGMYQDTS
                     GGPANFMRDYLISMTAFSMMSTAMFSFPAVLHTDKINNWQKTLRHTPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHFVRGVDMPLGSWIGAAFLLIVGSVAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGGINL
                     SATVYILVFSAVLFGLTIYLQGHKENA"
     gene            2590..3687
                     /locus_tag="VUR43_000492"
     CDS             2590..3687
                     /locus_tag="VUR43_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5412227.1"
                     /translation="MLERLKSIDYMYWASLIFMIFPILPVVTGEIPSWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGLMLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEYLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERSRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKVYLKLERTEKELILTVRYDGCGFVSISGDELHTVR
                     DRVLPFSGEVEVISWKQPTEVQVRLPYKERN"
     gene            3689..4288
                     /locus_tag="VUR43_000493"
     CDS             3689..4288
                     /locus_tag="VUR43_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5412228.1"
                     /translation="MKLLVAEDQSMLRDAMCQLLTLQPDVESVFQAKNGQEAIQLLEK
                     ESVDIVILDVEMPVKTGLEVLEWIRAEKLETKVVVVTTFKRSGYFERAVKAGVDAYVL
                     KERRIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            4713..5723
                     /gene="ccpA"
                     /locus_tag="VUR43_000494"
     CDS             4713..5723
                     /gene="ccpA"
                     /locus_tag="VUR43_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET5412229.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNSYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            5787..6080
                     /locus_tag="VUR43_000495"
     CDS             5787..6080
                     /locus_tag="VUR43_000495"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412230.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     SKHCFEVADRTDEVSSKHVFEVVDRTDEVSSKHVFEVVDETDEVSNHTYGKAT"
     gene            complement(6109..7071)
                     /locus_tag="VUR43_000496"
     CDS             complement(6109..7071)
                     /locus_tag="VUR43_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET5412231.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVYNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            7137..8525
                     /locus_tag="VUR43_000497"
     CDS             7137..8525
                     /locus_tag="VUR43_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5412232.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            complement(8560..9012)
                     /locus_tag="VUR43_000498"
     CDS             complement(8560..9012)
                     /locus_tag="VUR43_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET5412233.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            9174..9467
                     /locus_tag="VUR43_000499"
     CDS             9174..9467
                     /locus_tag="VUR43_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412234.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            9623..10837
                     /locus_tag="VUR43_000500"
     CDS             9623..10837
                     /locus_tag="VUR43_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5412235.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            10982..11116
                     /gene="rpmH"
                     /locus_tag="VUR43_000501"
     CDS             10982..11116
                     /gene="rpmH"
                     /locus_tag="VUR43_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET5412236.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            11400..12299
                     /locus_tag="VUR43_000502"
     CDS             11400..12299
                     /locus_tag="VUR43_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET5412237.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKEKV
                     KVAILQANGSALDGATINVAGYGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATP
                     EYKLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESA
                     KNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETI
                     GVQAIVMVTVPKRPVAPNAAPKTTSTPQATAGTMQDVTYQSPAGKQLPNTGSASSAAL
                     ASLALAAATSGFALLGRKTRRRK"
     gene            12604..13377
                     /locus_tag="VUR43_000503"
     CDS             12604..13377
                     /locus_tag="VUR43_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET5412238.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            13377..13937
                     /gene="rnmV"
                     /locus_tag="VUR43_000504"
     CDS             13377..13937
                     /gene="rnmV"
                     /locus_tag="VUR43_000504"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET5412239.1"
                     /translation="MKERISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            14009..14152
                     /locus_tag="VUR43_000505"
     CDS             14009..14152
                     /locus_tag="VUR43_000505"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412240.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     CPS"
     gene            14194..14907
                     /locus_tag="VUR43_000506"
     CDS             14194..14907
                     /locus_tag="VUR43_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET5412241.1"
                     /translation="MPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEIYKTY
                     FDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLLIRLF
                     FYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDC
                     FNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGD
                     GFLVKKLTEEWQEDVKKYL"
     gene            15221..15517
                     /locus_tag="VUR43_000507"
     CDS             15221..15517
                     /locus_tag="VUR43_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET5412242.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGND
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            15594..17624
                     /locus_tag="VUR43_000508"
     CDS             15594..17624
                     /locus_tag="VUR43_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET5412243.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYVTYGEGKLPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGPRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYIP
                     SGNVIYVSPRYLIEEKITVSSEFIDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            17626..18267
                     /locus_tag="VUR43_000509"
     CDS             17626..18267
                     /locus_tag="VUR43_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412244.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            18260..18568
                     /locus_tag="VUR43_000510"
     CDS             18260..18568
                     /locus_tag="VUR43_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412245.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            18699..19571
                     /gene="rsmA"
                     /locus_tag="VUR43_000511"
     CDS             18699..19571
                     /gene="rsmA"
                     /locus_tag="VUR43_000511"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET5412246.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            19573..20451
                     /gene="rsgA"
                     /locus_tag="VUR43_000512"
     CDS             19573..20451
                     /gene="rsgA"
                     /locus_tag="VUR43_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET5412247.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            20462..21118
                     /locus_tag="VUR43_000513"
     CDS             20462..21118
                     /locus_tag="VUR43_000513"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET5412248.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRLLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            21081..21743
                     /locus_tag="VUR43_000514"
     CDS             21081..21743
                     /locus_tag="VUR43_000514"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET5412249.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            21745..23001
                     /locus_tag="VUR43_000515"
     CDS             21745..23001
                     /locus_tag="VUR43_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET5412250.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQTSFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            22991..23932
                     /locus_tag="VUR43_000516"
     CDS             22991..23932
                     /locus_tag="VUR43_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET5412251.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            24199..25026
                     /gene="purR"
                     /locus_tag="VUR43_000517"
     CDS             24199..25026
                     /gene="purR"
                     /locus_tag="VUR43_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET5412252.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            25093..26343
                     /locus_tag="VUR43_000518"
     CDS             25093..26343
                     /locus_tag="VUR43_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET5412253.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            26469..27263
                     /gene="pflA"
                     /locus_tag="VUR43_000519"
     CDS             26469..27263
                     /gene="pflA"
                     /locus_tag="VUR43_000519"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET5412254.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(27338..28264)
                     /gene="yidC"
                     /locus_tag="VUR43_000520"
     CDS             complement(27338..28264)
                     /gene="yidC"
                     /locus_tag="VUR43_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET5412255.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPLLLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(28342..28620)
                     /locus_tag="VUR43_000521"
     CDS             complement(28342..28620)
                     /locus_tag="VUR43_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET5412256.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            28654..29394
                     /locus_tag="VUR43_000522"
     CDS             28654..29394
                     /locus_tag="VUR43_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET5412257.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            29450..30133
                     /locus_tag="VUR43_000523"
     CDS             29450..30133
                     /locus_tag="VUR43_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET5412258.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            30246..31238
                     /locus_tag="VUR43_000524"
     CDS             30246..31238
                     /locus_tag="VUR43_000524"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET5412259.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            31303..31842
                     /gene="rsmD"
                     /locus_tag="VUR43_000525"
     CDS             31303..31842
                     /gene="rsmD"
                     /locus_tag="VUR43_000525"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET5412260.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            31832..32320
                     /gene="coaD"
                     /locus_tag="VUR43_000526"
     CDS             31832..32320
                     /gene="coaD"
                     /locus_tag="VUR43_000526"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET5412261.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            32304..33341
                     /locus_tag="VUR43_000527"
     CDS             32304..33341
                     /locus_tag="VUR43_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET5412262.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            33399..33629
                     /locus_tag="VUR43_000528"
     CDS             33399..33629
                     /locus_tag="VUR43_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET5412263.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            33653..34936
                     /gene="murA"
                     /locus_tag="VUR43_000529"
     CDS             33653..34936
                     /gene="murA"
                     /locus_tag="VUR43_000529"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET5412264.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMIVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            34929..35117
                     /locus_tag="VUR43_000530"
     CDS             34929..35117
                     /locus_tag="VUR43_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET5412265.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            35156..35980
                     /gene="endA"
                     /locus_tag="VUR43_000531"
     CDS             35156..35980
                     /gene="endA"
                     /locus_tag="VUR43_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET5412266.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            36271..37602
                     /locus_tag="VUR43_000532"
     CDS             36271..37602
                     /locus_tag="VUR43_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET5412267.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(37800..37870)
                     /locus_tag="VUR43_000533"
     tRNA            complement(37800..37870)
                     /locus_tag="VUR43_000533"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(37836..37838),aa:Cys,seq:gca)
     gene            38286..41897
                     /gene="rpoB"
                     /locus_tag="VUR43_000534"
     CDS             38286..41897
                     /gene="rpoB"
                     /locus_tag="VUR43_000534"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET5412268.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            41930..45607
                     /gene="rpoC"
                     /locus_tag="VUR43_000535"
     CDS             41930..45607
                     /gene="rpoC"
                     /locus_tag="VUR43_000535"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET5412269.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            45718..46131
                     /gene="ndk"
                     /locus_tag="VUR43_000536"
     CDS             45718..46131
                     /gene="ndk"
                     /locus_tag="VUR43_000536"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET5412270.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(47059..47691)
                     /locus_tag="VUR43_000537"
     CDS             complement(47059..47691)
                     /locus_tag="VUR43_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412271.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(47693..49708)
                     /locus_tag="VUR43_000538"
     CDS             complement(47693..49708)
                     /locus_tag="VUR43_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET5412272.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFGALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLTI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNFITSTEWHDY
                     SPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEDHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(49811..50107)
                     /locus_tag="VUR43_000539"
     CDS             complement(49811..50107)
                     /locus_tag="VUR43_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET5412273.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPYNW
                     GAFSNYYHGSQYHWAYVGSNERDNQKTVYAGAHSAAYAFVNTNLGERITFDAGW"
     gene            50779..51642
                     /locus_tag="VUR43_000540"
     CDS             50779..51642
                     /locus_tag="VUR43_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412274.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDNLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            52025..52645
                     /locus_tag="VUR43_000541"
     CDS             52025..52645
                     /locus_tag="VUR43_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412275.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            52731..53174
                     /gene="tsaE"
                     /locus_tag="VUR43_000542"
     CDS             52731..53174
                     /gene="tsaE"
                     /locus_tag="VUR43_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET5412276.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            53164..53682
                     /locus_tag="VUR43_000543"
     CDS             53164..53682
                     /locus_tag="VUR43_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412277.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            53690..54706
                     /locus_tag="VUR43_000544"
     CDS             53690..54706
                     /locus_tag="VUR43_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET5412278.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            54791..56047
                     /locus_tag="VUR43_000545"
     CDS             54791..56047
                     /locus_tag="VUR43_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET5412279.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGNKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            56102..57268
                     /gene="recA"
                     /locus_tag="VUR43_000546"
     CDS             56102..57268
                     /gene="recA"
                     /locus_tag="VUR43_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET5412280.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            57575..58945
                     /locus_tag="VUR43_000547"
     CDS             57575..58945
                     /locus_tag="VUR43_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET5412281.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            59321..60277
                     /gene="lytA"
                     /locus_tag="VUR43_000548"
     CDS             59321..60277
                     /gene="lytA"
                     /locus_tag="VUR43_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET5412282.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            60636..60797
                     /locus_tag="VUR43_000549"
     CDS             60636..60797
                     /locus_tag="VUR43_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412283.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            60784..60990
                     /locus_tag="VUR43_000550"
     CDS             60784..60990
                     /locus_tag="VUR43_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412284.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            61012..61530
                     /locus_tag="VUR43_000551"
     CDS             61012..61530
                     /locus_tag="VUR43_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412285.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQFASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIV
                     YGLDEEGELSFD"
     gene            61523..61948
                     /locus_tag="VUR43_000552"
     CDS             61523..61948
                     /locus_tag="VUR43_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412286.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            62356..62940
                     /locus_tag="VUR43_000553"
     CDS             62356..62940
                     /locus_tag="VUR43_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412287.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            62944..63141
                     /locus_tag="VUR43_000554"
     CDS             62944..63141
                     /locus_tag="VUR43_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412288.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            63131..63682
                     /locus_tag="VUR43_000555"
                     /pseudo
     CDS             63131..63682
                     /locus_tag="VUR43_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            63741..64001
                     /locus_tag="VUR43_000556"
     CDS             63741..64001
                     /locus_tag="VUR43_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412289.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(64759..65155)
                     /locus_tag="VUR43_000557"
                     /pseudo
     CDS             complement(64759..65155)
                     /locus_tag="VUR43_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            65280..65738
                     /locus_tag="VUR43_000558"
     CDS             65280..65738
                     /locus_tag="VUR43_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET5412290.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            65751..66359
                     /locus_tag="VUR43_000559"
     CDS             65751..66359
                     /locus_tag="VUR43_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412291.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            66430..66762
                     /locus_tag="VUR43_000560"
     CDS             66430..66762
                     /locus_tag="VUR43_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412292.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            66773..68188
                     /gene="ply"
                     /locus_tag="VUR43_000561"
     CDS             66773..68188
                     /gene="ply"
                     /locus_tag="VUR43_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET5412293.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            69069..69785
                     /locus_tag="VUR43_000562"
     CDS             69069..69785
                     /locus_tag="VUR43_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5412294.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            69909..70379
                     /locus_tag="VUR43_000563"
     CDS             69909..70379
                     /locus_tag="VUR43_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET5412295.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            70395..71216
                     /locus_tag="VUR43_000564"
     CDS             70395..71216
                     /locus_tag="VUR43_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412296.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMLFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLT
                     RTTNDITQVQMLITMGLQVVTRGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIIFMSYAM"
     gene            71223..72254
                     /locus_tag="VUR43_000565"
     CDS             71223..72254
                     /locus_tag="VUR43_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5412297.1"
                     /translation="MGFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSVTAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIACALLKDASLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            72319..72681
                     /locus_tag="VUR43_000566"
     CDS             72319..72681
                     /locus_tag="VUR43_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET5412298.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGEKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERITITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            72678..73112
                     /locus_tag="VUR43_000567"
     CDS             72678..73112
                     /locus_tag="VUR43_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET5412299.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSAGRSM
                     PSRHVFSALLGLVRVLGGVHYPKDVLVGYACGLVWGFLFFLF"
     gene            73226..73672
                     /locus_tag="VUR43_000568"
     CDS             73226..73672
                     /locus_tag="VUR43_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5412300.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            73677..74351
                     /locus_tag="VUR43_000569"
     CDS             73677..74351
                     /locus_tag="VUR43_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412301.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGTAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            74607..74795
                     /locus_tag="VUR43_000570"
                     /pseudo
     CDS             74607..74795
                     /locus_tag="VUR43_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
     gene            75045..75344
                     /locus_tag="VUR43_000571"
     CDS             75045..75344
                     /locus_tag="VUR43_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET5412302.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            75341..75658
                     /locus_tag="VUR43_000572"
     CDS             75341..75658
                     /locus_tag="VUR43_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET5412303.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     SNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            75674..76300
                     /locus_tag="VUR43_000573"
     CDS             75674..76300
                     /locus_tag="VUR43_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET5412304.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKDKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            76333..77094
                     /locus_tag="VUR43_000574"
     CDS             76333..77094
                     /locus_tag="VUR43_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET5412305.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            77172..77567
                     /locus_tag="VUR43_000575"
     CDS             77172..77567
                     /locus_tag="VUR43_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET5412306.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            77837..78121
                     /gene="groES"
                     /locus_tag="VUR43_000576"
     CDS             77837..78121
                     /gene="groES"
                     /locus_tag="VUR43_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET5412307.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            78137..79759
                     /gene="groL"
                     /locus_tag="VUR43_000577"
     CDS             78137..79759
                     /gene="groL"
                     /locus_tag="VUR43_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET5412308.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISNRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(79858..>80522)
                     /locus_tag="VUR43_000578"
     CDS             complement(79858..>80522)
                     /locus_tag="VUR43_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5412309.1"
                     /translation="IRDHFLKYDRAVRCRVKIITMDMFSPYYGLAKQLRFHIVQHLSR
                     AMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKQFYRPTFRMHLTNKEILN
                     KLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKE
                     KIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLS
                     RA"
BASE COUNT        24037 a        14744 c        18163 g        23578 t
ORIGIN      
        1 acagagatat gtgagtgtgt atttttaaaa ctagatatta tatacattaa gagggaatca
       61 gtttggttct ctcttttttg attttcagta attcattttg gcagcgtata ctttttgtct
      121 ccagtctttt caataaatac cgtagtttag atatacacat tgaaatttaa cagattttat
      181 aactcttata aatttttaag aaagcaatag aagggttttg ttcaacgtat aatatagaga
      241 attgaaataa gatatgaaca gttctatcag gaaagttaaa ttaatttata gaaatatttt
      301 agtatttaag gcctactgtt atagattcaa tacactatat atgtgtttgt ctgataaaaa
      361 tttctactct ttttgatttt aaataagtat tagtttacat tatggtgtga attgagtttg
      421 atatctcttt tgaggaagtt gccttagatt tttctgattg tgttttattg tatagtgtat
      481 cttgcttgtt ttgaacagaa ttttttatga catttgtcat attttctagt gacagaagct
      541 tctgtctcct ctgattttaa aagactataa ttgtagtatg aaatggggga agaagagatg
      601 agaaataaaa tgattatcgc agtaagttta gtagtagcag gagttatgac ctatctcatg
      661 ttttcgggat tggatgagga tttctaccat tttccttgga aggtctttgc tggctttgga
      721 atcatgtctt ggcttgttag agaaggtttg aaattagtca gagatgtgaa aaaggagttt
      781 gaggaatgaa gagagggatc atctatttct ttatcggcct gtcactcttg gtatggttag
      841 tggaaatgtt tactgattgg tttgatcaag ccttgcttcg ccaattcatt cgtggtgctt
      901 tggggtttgg atttatgatt ttcttcgttt tccttatggg aatggagtgg ttgaaaggag
      961 agtctcatga cggtggttaa agttgagaaa ttgagtaaga aaataaaaga caaggaaatt
     1021 ttgcggaata tctcctttga aatcaacgat ggtgaatgtg ttgccttaat tggtccaaat
     1081 ggtgccggaa agacaacact cttagattgt ttgcttggag ataaactggt cacaagcggt
     1141 caagtatcta ttcaaggttt accagtgacg agttctaagt tagactatac tagggcttac
     1201 ctccctcaag aaaatgtaat cgttcagaaa ttaaaagtta aagagttgat tgctttcttt
     1261 caacgtatct atccaaatcc tttgagcaat caggaaattg atcaactatt gcagtttgtc
     1321 aagcaacaaa aagaacagtt ggcagaaaaa ttatcaggcg gtcaaaagcg tctcttttct
     1381 ttcatcttga ccttaattgg gcgaccaaag attgtttttt tagatgagcc tactgcgtcc
     1441 atggatacct caactcgtca acgtttttgg gaaattgtcc aggagttaaa agcgcaagga
     1501 gtcaccattc tctattcgtc ccattatatc gaagaggtag agcatacagc ggaccgaatc
     1561 ttggtcttga ataagggaga gttgattcgc gatacaacac ctctagccat gcgtagcgag
     1621 gaaattgaaa agcattttat ccttcctctg gcttacaagg aagtcgttga gcagtcaaac
     1681 ttggctgaaa actgggtaca aaaacaagat gccctgcaag tagtcacgcg agaggcaaat
     1741 gctttctggc aactgttagt ccaagcagga tgtagcatac aagaaatcga agttaataac
     1801 cgtagtttgc tagatacaat ctttgaagaa acacaaaagg gagatgacta agatgaaacg
     1861 atggatcgca ctaaacaaga tagaatttct attgaccaaa cgacaattag tctattatct
     1921 attatccgta gggatgccga cagccttcta tttatttttt tcaggcatgt accaggacac
     1981 atcaggtggg cccgcgaatt ttatgcgtga ttacctcatc tccatgacag ccttttccat
     2041 gatgtcgaca gctatgtttt cattcccagc tgtcttacat actgataaaa tcaacaactg
     2101 gcagaaaaca ttgcgccata cccctgtaaa tatggtagaa tattatctat caaagataac
     2161 aagtatgatg gttgattatt tggtatcaat tctggttgtt ttctcagttg ggcattttgt
     2221 aagaggtgtg gatatgcctc taggaagttg gattggggct gcgttcttgc tgatagtagg
     2281 aagtgttgcc tttgtagcgc ttggcttgac cttgacactc ttgccttcta gtcagttgat
     2341 gtctgtcgtg ggcaatcttc tctatctagg cttggctgtt ttaggcggac tctggatgcc
     2401 catctcttta tttccagact ggatgcaagc aatcgggaag tgcctaccaa cttatcagtt
     2461 gatggagttg ctcaaaacct tcttaaacga gggtggcatc aatctatcag ccacagttta
     2521 tatacttgtt ttttcagcag ttttgtttgg tttgaccatt tatcttcaag gtcataagga
     2581 gaatgcttaa tgcttgaaag actaaaaagc atagactata tgtattgggc cagtttaatt
     2641 tttatgattt tccccatcct acctgtagtg actggggaga ttcctagctg gcatttattg
     2701 attgatattc tatttgtagt ggcgtatttg ggtgttttaa caactaagag ccagcgccta
     2761 tcttggctat attggggcct catgctgact tatgtagttg ggaatactgc ctttgttgct
     2821 gttaattata tctggttttt ctttttccta tccaatctct taagttatca tttcagcgta
     2881 ggtggtttaa agtctttaca tgtctggact tttcttcttg ctcaagtcct tgttgtgggc
     2941 caacttttga tttttcagag aatcgaagtt gagtatctat tctatctact tgtaattctt
     3001 gcttttgtcg atttaatgac ttttggcttg gttcggattc gtattgtgga ggatttgaaa
     3061 gaagctcagg ctaagcaaaa tgcccagata aatctattgc ttgctgaaaa tgaacgcagt
     3121 cgtatcggtc aagatttgca tgatagtctg gggcatacct ttgctatgtt gagtgtcaag
     3181 acagatttag ccttgcagtt atttcaaata caggcttatc cacaggtgga aaaggaatta
     3241 agagaaatac agcaaattag caaagaatca atgcgtgaag tgcgaaccat tgtggaaaat
     3301 cttaagtcta gaactttgac atccgaacta gagactgtga aaaagatgtt agaaattgct
     3361 ggaattgagg tggaaatagc taatcaacta gatacagcta gccttactca ggaattggag
     3421 tcaacggctt ccatgatttt gcttgaatta gtgaccaata tcatcaaaca tgctaaagcg
     3481 tctaaagtct acttaaaatt agaacggaca gagaaagaac tcattctaac agtgagatat
     3541 gatggctgtg gctttgtttc tataagcggg gatgagctcc atacagttcg agatcgtgtt
     3601 cttccatttt cgggagaagt agaggtaatt agttggaaac aaccgacaga agttcaggtt
     3661 cgactacctt ataaggagag aaactaagat gaaactactt gttgcagaag atcaaagtat
     3721 gttgcgggat gccatgtgcc agttgctcac gcttcaaccg gatgtagagt ctgtctttca
     3781 agccaagaat gggcaagaag caatccaact attagaaaag gagtctgtgg atatcgtcat
     3841 ccttgatgta gaaatgcccg ttaagacagg tcttgaagtc ttggagtgga tacgagcaga
     3901 aaagcttgaa acaaaggtgg ttgtagtgac gaccttcaag cgctcagggt attttgaacg
     3961 tgcggtcaag gctggagtag atgcttatgt attaaaagaa agaaggattg cagacctcat
     4021 gcaaaccttg cacaccgtcc tcgaaggacg caaggagtat tcgcctgaat tgatggaagt
     4081 ggtgatgacc cgtcccaatc cgttgacaga acaagagatt gctgtcttaa aggggatcgc
     4141 ccggggctta tccaaccaag aaatcgcaga tcagctttac ctctcaaacg gaactattcg
     4201 aaactatgtc accaatattc tttcaaaatt ggatgctggt aatcgaacag aggcagctaa
     4261 tatcgcaaaa gaatctggtt ggttatgatg atataatgtt ttcatgaaga ctatgtgcta
     4321 aaattgacgg tagtgaatgg aacaatacct atagtagatt gaaactagaa tagtacacct
     4381 ctacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgattta tcctgttctt
     4441 atttcatttt actataactt taggagggct tagtttcctc ctttttgttt agtctaaggt
     4501 ggtagcaagg agctaaacct aggttttcta tgaaattttt tcaatcaatc ttcaaaaaac
     4561 acttgaaagt gtttacaatt agtgatagaa tggaataagt agaaatatga aaacgaaatt
     4621 ttcacatctt cacttttgta agtagatata gagcttcaat cagtacctct acttgtaaaa
     4681 gaatgtgtga gatagaaagg acaggaaaag gaatgaatgc agatgataca gtaaccattt
     4741 atgatgtcgc tcgtgaagca ggtgtttcca tggcgacggt cagccgtgtg gtcaatggca
     4801 ataaaaatgt aaaagagaat acccgtaaaa aagtgctaga ggtaattgat cgcttggatt
     4861 atcgtccaaa tgcagttgcg cgtggtcttg caagtaaaaa gacaaccact gtcggtgtcg
     4921 tgattccaaa tattaccaat agttattttt cgagtttggc taaggggatt gatgatattg
     4981 cagaaatgta caagtacaat attgtcctag ctaatagcga tgaagataac gagaaagaag
     5041 tttctgttgt caataccctc ttttcaaagc aggtagatgg cattatctat atgggttatc
     5101 acttgacaga taaaattcgc tcagaatttt cgcgttcacg tactccgatt gttctcgcag
     5161 gaactgtcga tgttgagcac cagttgccaa gtgtcaatat tgactataag caagcaacaa
     5221 ttgatgcagt gagttacctt gctaaagaaa atgagcgtat tgctttcgtt agcggtccgc
     5281 tagtggatga catcaatggt aaggttcgtt tagttggcta caaggaaacc ttgaaaaaag
     5341 caggaatcgc ttatagtgag ggtttggtat ttgaatctaa atatagctat gatgatggtt
     5401 acgccttagc agagcgtttg atttcatcaa atgcaactgc agcagttgtg acaggtgatg
     5461 agttggcagc aggagtcttg aacggtttgg ctgataaggg tgtttctgtg ccagaagatt
     5521 ttgaaattat tactagtgat gattcacaaa tctcacgctt tacccgtcca aacttgacaa
     5581 cgattgccca acctctttat gaccttggtg ccattagtat gcgtatgttg accaagatta
     5641 tgcataagga agagttggaa gaacgtgaag ttctcttacc tcatggtttg acagaacgta
     5701 gctcaacacg aaaacgtaaa tagaaaaaat cagggaatcg agaagatttc ctgattttgt
     5761 gctcttaaac aagagatgtt gacttaatga ataccataga gcggactagg cggctggtta
     5821 aaggctgcgc aacacactgt tttgaggttg tagatagaac tgacgaagtc agctcaaagc
     5881 actgctttga ggttgcagat agaactgacg aagtcagctc aaagcactgc tttgaggttg
     5941 cagatagaac tgacgaagtc agctcaaaac atgtttttga ggttgtagat agaactgacg
     6001 aagtcagctc aaaacatgtt tttgaggttg tggatgaaac tgacgaagtc agtaaccata
     6061 catacggtaa ggcgacgtga cgtggtttgc agagattttc gaagagtatt agccttccat
     6121 atagtctttc aaagcctgtc ctgttagtcc ggcattgagg gcgatgagga gtttcaagcg
     6181 ggctttttgg gcgttgagtt ctttaacaaa gaaaacgcct gctttttgca actgtacgcc
     6241 cccaccctgg taggcataaa caggctcggc aataccgtta aagcatcgtg ataccagagc
     6301 gactgggatt cctttttgca gaaggctttc taatttttga gccgtttctt tgggaatatt
     6361 accagctccg aaggcttgga taatcaaacc gtccaagtgt tctaaatcca gcatatcaat
     6421 cagctcatct gtcataccag cataagccga gatgataggg actaaacctt gtatgtgatc
     6481 aaggtcaaag cgaacacgag gttcagctgt tttgaagtag aggatttcct gtttcatgat
     6541 gagaccgagg gggccatgtg ttggagtctg gaaggtgctg acattagtcg tatgtgtttt
     6601 ggtgacatac ttggcagcgt ggatttcatc gttcataacg accaaaactc ctttgtcagc
     6661 agccctgtca tcgctggcca ctcgtaaagc acttaggtaa ttataaacac catcactccc
     6721 gagctcattg gagctacgca tggctcctgt tagaacgata ggcatatggg gaacttccat
     6781 ggtatcaagg aaataggctg tttcctctaa agtatcggtt ccgtgtgtga tcaccactcc
     6841 atcgtagtta tctgcttcct ctttaatttt ttggtagagg accagcatat gtttgggttt
     6901 gatatgggga cttggaaggt taaaaaagtc caaggcgtgg acttggattc cttcaagtgg
     6961 gttgtacaca tggttcatgg gattatctga actcgtcaca acagcgccag aagcatcggc
     7021 ctgcatggaa atagttccac ccgtatgtaa aacaaggatt ttcttaggca tgatttacta
     7081 actctttctg aaatgtggta taatcattgt atcacaaaag gggagattgg aataggatgg
     7141 aagtcaaagc tgtttttttt gatatcgatg gaaccttggt caacaatcgt aagagtgttt
     7201 tgaaatccac taaggacgcg attaagattg tcaaagaaca aggggtacta gttggcgtag
     7261 cgacagggcg aggacctttt tttgttaagg aattgatgga cgatttggat ctggattttg
     7321 cggtaaccta taatggccag tatatcttta gtaaagacag agtcttgttc acgagcccta
     7381 tttccaagtt acatttgcgc catctaatta gctatgctaa aaaagagggc acggagattg
     7441 ctctagggac caaggatgcc atgttgggtt ctaaaatcat gtcctttggt ctgggttctt
     7501 tttcccaacg aattagtcgc ttcgttccct ctgttttaac tcggacggtg agtcagtctt
     7561 ttaatcgcat ggtcagcaag gttgttcccc aaaaggaaga ggacctgctt cacctgatga
     7621 atcagcctat ctaccaagtt ttgatgctga tgacaccaga agaatctgag aaggcggcag
     7681 ctgattttga agacttgaaa ttgacacgta gcaatccttt tgcatcggat gtcatcaatc
     7741 agggaaattc taaattagaa ggcattcgcc gagttgggaa agaatatggc tttgacctca
     7801 atcaagtcat ggcttttggt gactcagata atgaccttga aatgctggct ggcgtcggta
     7861 tgtcggtcgc tatgggaaat ggtagtagca gtgtcaagga agctgccaag cacattacca
     7921 ctagcaatca acaagatggg atccacaagg ccttggaaca ttttggtgtt ttgtcttcag
     7981 aaaaagtctt tgtcagccgt gactatcatt tcaataaggt caagaccttc caccacatga
     8041 tggatgaacg aacccaagaa gaacctcgag cttgggattt agagggtgca acccataggg
     8101 ctggttttaa aatagaagaa ttggtggagt ttgttcgagc agccagtcct tctgaagaag
     8161 attttggtca agctgtatcg caacttcatc aggcccttga taaggcagca ggtaaagtag
     8221 ccaagaagac acctgctcag caagatttga tagggcaagt ggatgccttg attgacacgc
     8281 tttacttcac ctacggcagt tttgtcttga tgggggtgga cccagaacgt atttttgata
     8341 ttgtccatca ggccaatatg gggaaaattt ttccagatgg caaggctcat tttgatccag
     8401 tgacccataa aatcttaaaa ccagataatt gggaagaaaa atatgctcca gaacctgcta
     8461 ttaaaaagga actgcagcgc cagctcaagg cttacgaacg ccataaagag agaaataaat
     8521 cgtaaacaaa aaggagctag gggctccttt tctttgtgat tataaggttt tttcttgttc
     8581 tctcacaacc agcaaatcga ccttagcatg gcggagtatg tattcagatg aagagccgac
     8641 taagaggcgt tcaaaggcgt tgagaccagt tgcgccaacg aggatgaggt ccacttcctc
     8701 ggcatctgga atagtacgtg ctagcagggt ctttggattt cccatttcaa tgacgatatg
     8761 aacatctgct accccagcat ctttagcacg tttttcgtac tctttcatca gactttcagc
     8821 gtcgacttgg agttcttcgt aaacttcagc atcaaaggtg gatacgcttt ggagagcgcg
     8881 tgtgtcaatg acatgtacga tggtgagttt agcgtcgttt cgtagagcag aatgaactcc
     8941 cttgacaaaa gccaagtccg cttccttaga accatcgatt gcgaccatga tattttggta
     9001 acgttgtgcc ataatgaaac ctcctgaaat tttcttacta taattgtaaa ccttttcact
     9061 atagaagtaa agcaaaaaaa gtatttttca aaagaatatt agggcttaaa atctatataa
     9121 atatatgata aaataaaaga aaggatagca ggaaagaagt gaaggaaggg agaatgatga
     9181 aaaactcttt tcaaaaatca aatttcctgt attatggaat tatcctagtt tcagtcttgg
     9241 tagaagtgat catgatctgg caattagaga gtttggtacc gcttatttat ccaggtttta
     9301 ttggattttt agtctttcat gtactctacc atctaatctt atttctagtt gcaaaacgaa
     9361 gtgggcgttg ggattacttg atgatatggg ggcttttcct catgtttaat cttctttatg
     9421 actcctttct aggcttgctt tttctaggtt tatcttttgg tatgtgatgt gtctttgcaa
     9481 aatacctgct atctctacgt tcttaacctc gcctttagca aggtttttct tctatacgaa
     9541 actagtaaca catttcagta aacttgtcgc attctctttc tagtggtata atgttactat
     9601 cctgatgaat tgaggaaaca agatgaaaga atataacaag tctagtaagt tagagcatgt
     9661 tgcttatgat atccgtggtc ctgtattgga agaagccatg cggatgcgag cgaatggaga
     9721 aaagatttta cgtctgaata caggaaatcc agcagaattt ggctttacag cgccagacga
     9781 ggtcattcat gacttgatta tgaatgcgcg tgatagtgaa ggctattctg actccaaagg
     9841 gattttctca gcccgtaagg ccatcatgca gtattgccag ctgaagaaat tcccaaacgt
     9901 agatattgat gatatttacc ttggaaatgg tgtcagtgag ttgattgtca tgtccatgca
     9961 ggggcttttg gacaatgggg atgaggtctt agtgccaatg ccagactatc ctctatggac
    10021 ggcggctgtc agcctagctg gaggaaatgc cgttcactat atctgtgatg aagctgtgga
    10081 atggtaccca gatattgacg atatcaagtc aaaaatcact tccaatacca aggcaattgt
    10141 ccttatcaat ccaaataacc caactggagc cctttatcct aaggaactct tgctggggat
    10201 tattgagatt gcccgtcaaa acgatttgat tatctttgcg gatgaaatct atgaccgcat
    10261 ggtaatggac ggacatgtgc atacgcctgt ggcgagcttg gcaccagatg tcttctgtgt
    10321 cagcatgaat ggtctgtcaa aatcccaccg catagcaggt ttccgtgtgg gttggatggt
    10381 cttgtctggc cctaagactc atgttaaggg ctatatcgaa gggctcaata tgctgtccaa
    10441 tatgcgcctt tgctctaacg ttttggccca acaagtcgta caaacttcct tggggggtca
    10501 ccaatcagtc gatgaattgc ttcttcctgg tggacgaatc tacgagcaaa gaaatttcat
    10561 ctataatgcc attcaagata ttccaggttt gtctgccgtt aaacccaagg cggggctcta
    10621 tatcttccca aaaatcgacc gcaatatgta ccgtatcgat gatgatgagc agtttgtcct
    10681 tgatttcttg aagcaggaaa aggttctctt ggttcatggt cgaggcttta actggcagga
    10741 accagaccac ttccgtatcg tttaccttcc tcgtgttgat gagttagccc aaatccaaga
    10801 aaagatgact cgtttcttga aacagtatcg tagatagggc ttgcattcga aaaagctgga
    10861 aacatttgcc tagagctatt gacaaaagtg aaagaatcag atagaatagt aaagtatgtt
    10921 tagtaactga tcactttata gccggctaaa cgaatacaaa atctatgagg aggtattcat
    10981 cgtgaaacgt acttatcaac caagtaaact tcgtcgtgcg cgcaaacacg gattccgtaa
    11041 ccgtatgtca actaaaaatg gtcgtcgcgt attggcagct cgtcgtcgta aaggacgcaa
    11101 agttttggct gcataatcca aacgaattct atcaaaaatc agtaggaact cgagtctact
    11161 gatttttatt tttgtaaaaa agttcagtag atgcaaatgg attcggaagc gatgttacag
    11221 tagattgaaa ctagaatagt acacctctgt ttctaaaaca ttgttagaaa tcgatttgac
    11281 tgtcctgatc gatttgtcct gttattattt tattttacta taaagttgaa gtaggtggag
    11341 atggtacagc aacaatcgtc tttaaagatg gttcagctat tacaattcca ggaaatcaat
    11401 tggtagcaca agatccaaaa gcacaagata gcactaaacc gactgctgaa aaatcaactg
    11461 ttaaagcacc tgctcaaaga gtagatgtaa aagatataac tcatttaaca gatgaagaaa
    11521 aagaaaaagt taaggttgct attttacaag caaatggttc agcattagac ggagcgacaa
    11581 tcaatgtagc tggatatggt acagcaacaa tcacattccc agatggttca gtagtgacga
    11641 ttctaggaaa agatacagtt caacaatctg cgaaaggtga atctgtaact caagaagcta
    11701 caccagagta taagctagaa actacaccag gtggagataa gggaggcaat actggaagct
    11761 cagatgctaa tgcgaatgaa ggcggtggta gccaggcggg tggatcagct cacacaggtt
    11821 cacaaaactc agctcaatca caagcttcta agcaattagc tactgaaaaa gaatcagcta
    11881 aaaatgccat tgaaaaagca gccaaggaca agcaggatga aatcaaaggc gcaccgcttt
    11941 ctgataaaga aaaagcagaa cttttagcaa gagtggaagc agaaaaacaa gcagctctca
    12001 aagagattga aaatgcgaaa actatggaag atgtgaagga agcagaaacg attggagtgc
    12061 aagccattgt catggttaca gttcctaaga gaccagtggc tcctaatgct gctcctaaga
    12121 caacaagtac accgcaagca actgcaggaa caatgcaaga tgttacctac cagtcacctg
    12181 ctggcaaaca attacctaac acaggttcag catcaagtgc agcacttgct agtcttgctc
    12241 tagcggcggc aacaagtggt tttgctttgc taggaagaaa gactagacgt agaaaataga
    12301 acagctagaa aattctattc tctacttaaa gttagattat aagagggatt ttgagaagtc
    12361 atcaatccta gtgatgggtg agaaaagtga gaacccaaga taatcacata ctttagctga
    12421 ataggaatat tctatcaatg tagccaatct cttctgtctc taactgtgga ataggagatg
    12481 ggtaatatcg gatagaaaag atagcagaat agctccctat tgaagagagg aggggaaacc
    12541 gaaaaattag gtgcccctcc tcttttttgg tataatagaa gatagaaaac gaggttagaa
    12601 gagatgattt ttgatacaca tacacacttg aatgtagaag aatttgcagg tcgtgaggca
    12661 gaagaaattg ccttggctga tgagatgggt gtgacacaga tgaatattgt tggttttgat
    12721 aaaccgacga ttgagcatgc cttggagttg gtagatgagt atgagcagct ctatgcgact
    12781 attggttggc atcctacaga agctggtact tatacagagg aagttgaggc ttacttgttg
    12841 gataagttaa aacattccaa ggttgtggct ttaggtgaaa ttggcttaga ctaccattgg
    12901 atgacagcgc ccaaagaggt gcaggagcag gtttttcgcc gtcagattca gctatctaag
    12961 gacttggatt tgccttttgt tgtccatacc cgtgatgcgc tggaagatac ctatgagatt
    13021 atcaagagtg agggcgttgg tcctcgtggt ggtatcatgc attcattttc agggacgctt
    13081 gagtgggcag agaagtttgt ggatcttggt atgaccattt ccttctcagg agtggtgact
    13141 ttcaagaagg caactgacct ccaagaagca gctaaagagt tacctttgga caagatgttg
    13201 gtggaaacag atgcgcctta cttagcacct gtacccaagc gtggtcgtga aaataaaaca
    13261 gcctatactc gctatgtggt cgactttatc gctgacttgc gtggtatgac gacagaagag
    13321 ctggcggtag caacgactgc aaatgcagaa cgcatttttg gattggacag caagtaatga
    13381 aagagagaat ttcccaagtt atcgtggttg aaggtcgtga tgatacggtc aatctcaagc
    13441 gttatttcga tgtggagacc tatgagactc gaggttctgc catcaatgac caggacatag
    13501 agcggattca gcgtctacac caacgtcatg gagtcattgt ctttacagac ccagatttta
    13561 atggggagcg gattcggcgc atgattatga cggccattcc aacagttcag catgcctttc
    13621 tcaagcgaga tgaagctgtt ccaaagtcca agaccaaggg gcgttctctg ggaattgagc
    13681 atgccagcta tgaagacctg aaaacggctc tagctcaggt gacagaacaa tttgaacatg
    13741 agagtcagtt tgacattagt cgtagcgact tgattcgcct tggttttcta gcaggggcag
    13801 acagccgtaa gcgtagagaa tatctcggag agactctccg aatcggctat tctaacggca
    13861 agcaactcct caaacgccta gagttgtttg gggttacttt ggcagaagtg gaagaagcta
    13921 tgaaatctta tgagtaggaa agatgtagcc gttacaattt tttaagtttc acagtatttt
    13981 tcgaagcagg tagaagagga ggcgtctgat gttaattggt caaaaaatta aagagattcg
    14041 gatagaaaaa ggaattagtc gtccagattt ttgtggagat gagcaagaac tgacagttcg
    14101 tcaactgtcg cgaattgaaa gtggagcttc gcaaccgagt tgcccaagtt agactatatt
    14161 gctcaccggc taggagttcc agtttatagc cttatgccgg atttttcagc tcttcctcct
    14221 gcttatttag aattgaaata ccagatttta cgtgaaccaa tctatggtaa agaagaggag
    14281 tatgataaga aagaagcgtg tttggaagag atttataaaa catactttga taatcttcct
    14341 aaagaagaac aattagcatg tgaagtattg caggcgtgtt tggatacttc tagaactaga
    14401 aggcctgaat atgcagagtt aatacttgag gaacatatgc ctcagatcat agaaaaagaa
    14461 gtttattcaa caaatgatat gttgttgatt cgtttgtttt tttatcaaat gctcattaga
    14521 aaagatcttg ccaaatttat aaatcaaatc gaaaagctaa tgctctttct tttggaacag
    14581 aaaaaggtaa ctaaattaga aaacttcttt ataattagag atactcttat ttcaggaatg
    14641 tgttgtcttg aaaaggtagg agtaactgat tgttttaatg attatctatc gtgtttacaa
    14701 gaaattatgg ataaaactca agattatcaa aagaaacctc ttgtatttat gtttttgtgg
    14761 aagcaagcat taagagtaga aagagatttt agtttagctg aatcatttta tcagtcttct
    14821 aaaacatttg cgaagctaat tggagatgga tttctagtaa agaaattgac agaggaatgg
    14881 caagaggatg tcaaaaaata tttataaaca tagtgaatca gtgacaaaaa tgtccttgtc
    14941 ctcgtatcaa aacagttcta aagttcgtct ttagaactgt ttttttagat ataagctaaa
    15001 aataatatga aatagttaga ttttaaggac attgatgtcc ttgatagtgt gataaagatg
    15061 gagtataatg actataaaag ttcatttcag ggtgctattt tgacaattta gagaaaaaca
    15121 aataatttta gaatatcatt tggtaatata atagtatcaa cgttgataat ggaaagagga
    15181 gcatcaacaa tcttgtaatc aaaaatagag gagtatcaat atgaaacaaa cagttaaaaa
    15241 attagctctt gtagcgagca ttgcagcaac attaggtgga agtgtagcag ttgcctctgc
    15301 agccgttcaa tacccagaag gtggtgtttg gacttatggt tcaggtaacg atggtgctta
    15361 ctcaaactac tatcaccctt caaaatacca tagttcaaca gttgttagca gaaaaactgg
    15421 ttcatctgac aagggatatg ctggtgctgg agggacttct cgtgcatgga ttcgtacttc
    15481 ttggggagag aaagttgcat tctactataa tgtttagaat ggtatagccc tattgtttag
    15541 ctttacttgg tcaccttctc actaagtgac caagtaactt tttggaggaa atgatgaaac
    15601 gtttatttat tttgatttca atggtattgg tatcgcttta tatggtgata acttccgttg
    15661 accatcgaga agagatttta tttggtaact atccttctgt tgatgtgaca ggaatgatga
    15721 taaatcaacc agtagctagc cgcgaagagg tgacagaggc tttgagtcac ttggcggtag
    15781 agcataatag tctcatcgcc cgtcggattg ttgagccaaa tgaagctgga gaaacacgct
    15841 ttacctatgt cacttatggt gagggaaagc ttccagaagg tctgaccatt tcctccaagg
    15901 agagtgcaga aacgagtgat ttattagggt cttacttgat tgtatcagga agtttggatg
    15961 gagtgagctt acagaccacc ttgaaagagc ttggttatca aggctttgtt tcgaatggag
    16021 aagatccatt ttcgatagtc ttactattgg cggccacccc tatggtgcta ctgagtttag
    16081 ctatttttct gctgaccttt atgagtctga ccctgattta tcggatcaaa tcccttcgtc
    16141 aggcagggat tcgcttaata gctggtgaga gcttgtttgg agttgctctc agaccagtgt
    16201 tagaagatgt gagacagctt atctgctcag tgctggtatc cagtcttttg ggattgggga
    16261 ttctctggta tcaaggtgcc ttgtttatgg caacggtaca actggtcatc attgctcttc
    16321 tactttatgg attgaccctg gcagggattt ctaccttact aagtgtcgtc catctacttg
    16381 gtttacagga aaatagtctg gtggatctat tgaaagggaa actccctctc aaacggatga
    16441 tgacattgat gatggtgggg caactcttag ctgtattggt ggtcggatcg agtgcgacag
    16501 ctctcctacc ccactaccgt gaaatgcagg aaatggagag agctagcaat aaatggagcc
    16561 agtcctcaga ccgttaccgt ctatcctttg gttggtctag tgcatttgcc gatgaagaag
    16621 gaccgcgtaa ggataatcgt gagtggcaga catttactga agaacggtta gccaatacag
    16681 actcttttta tattatgagc aatgttgaca atttctcaga tggagcagaa gtggacctag
    16741 atggcaatcg tctcagtgac tacataccgt cagggaatgt tatctatgtc tcgccgcgct
    16801 atctgataga agaaaagatt accgtttctt cagagtttat tgacaagatg caaaacttgt
    16861 ctgagggaga gtttgggctg atcttgcctg agagcttgcg agagcagtct gcctactacc
    16921 aaggattgtt tacagattac ctgcaaaact tttcatctga aagtgtagaa gtgacgagtc
    16981 agaaacacta cttcccacag gtaaggctag cttttacaga aacaggacag gaacgtttcc
    17041 tctataatga tgggtacaag acaacacgcc agtacctaaa agatccgatt attgtagttc
    17101 taacgccgca agcgactgga acaagacctg ttgcagggat gttgtgggga actacggcta
    17161 atagtgcctt gaaactagat cgatatggag acagcatcac agctctaaaa gagcaaggtc
    17221 tgtatcacaa ggtttcttac ttggtaaaaa gccagctatt ttttgccaag gtactaaatg
    17281 acaaacgggt ggagttttac tctctcctta ttgggacgat tttgaccctg tctacggcta
    17341 tcttgttatt tgattccatg aatcttctct attttgagca gttcagacgg gagcttatga
    17401 ttaaacgtct tgctggtatg acaatctatg agcttcatgg caagtattta ctggcgcaag
    17461 gaggagttct cttgcttggc ctagtcctat ctagtatttt gacaagagat ggtttgatta
    17521 gcgctctagt tgtagctttg tttacgctta acgccctctt gattttagta aggcaggaca
    17581 aaaaagaaga agctggtagc atggcagtat tgaaaggaaa ataagatgat tgatattcaa
    17641 ggattggaaa agaaatttaa tgaccgcgcg attttctctg gtttgaatct caagctggag
    17701 aagggcaagg tttatgcctt aatcggaaag agtggaagcg gaaagacgac gctgctgaat
    17761 atcttgggaa agctagaaaa gatagatgga ggaagggttc tctatcaggg gaaagattta
    17821 aaaaccattc ccactcgtga gtattttcga gatcagatgg gctatctctt tcaaaatttt
    17881 ggcctcttag aaaaccaatc aatcaaagaa aatttggatt tgggttttgt tggtcagaaa
    17941 atctcaaaag tagaacgttt ggaaaggcaa gtgggggctt tagaaaaagt taatctaggg
    18001 tatttggatt tagaacaaaa aatttatact ttatctgggg gagaggccca acgagttgcc
    18061 cttgctaaga ctattttgaa aaatccaccc ttgattttgg cagatgaacc aacagcagct
    18121 cttgatcctg aaaattcaga ggaggttatg aatctcttgg tggatttgaa agatgaaaat
    18181 cgaattatca tcattgcgac ccataatccc ctagtctgga ataaggctga tgaaatcatt
    18241 gatatgagga aacttgctca tgtgtgaaaa aatccgtatt cgcagggtat ctgattatcc
    18301 tagtgccaga ggtggtttag aagatatcct catcatggaa aatatgacca atcatctcct
    18361 tttggttcaa atccgagtgc atggctattt gcttgatttt gctagtattg aagggcaaag
    18421 gcaaaagcat tatcgtttga aaaatttacc tcagacggtt gaactgacag tggatgatgt
    18481 ggaggaggat gtggatttga ccctacctga aaatcgaagt tatcaagaag ctgatttttt
    18541 tgaacgcatg tttcgagaga actgttaagg ccacttttaa agatttccaa gactatcttt
    18601 cttcatgagg aaagatagtt ttttggtatg attttcattc ccaaaataca aggggaatgt
    18661 gttacaatag tagtaacaga taatagaaaa gagaatagat gagaattgca gattatagcg
    18721 tgaccaaggc agtgctggag cgtcacggtt ttacctttaa aaagtccttc gggcaaaatt
    18781 tcctgacgga taccaatatc cttcaaaaaa ttgtggatac ggctgaaatt gatgaccagg
    18841 tcaatgtcat cgaaatcggg ccaggtattg gtgccttgac ggagtttctg gctgagcgtg
    18901 cagcccaagt catggctttt gagattgacc accgtttggt gccaattttg gtagataccc
    18961 tgcgtgattt tgataatgtg actgtagtta acgaagatat tctcaaggtt gatttggcgc
    19021 aacatatcca aaattttaaa aatcctaacc tgccaatcaa ggtagtggct aatttgcctt
    19081 actacatcac gacgcctatt ctcatgcact tgattgagag tggcattcct ttttgtgagt
    19141 ttgtggtcat gatgcagaaa gaagtagcgg accgcatttc agcccagcct aacaccaagg
    19201 cttacggtag cttgtctatc gccgtgcagt attacatgac agccaaggtt gcctttatcg
    19261 tgcctcgtac ggtctttgtg ccagcgccaa atgtggattc agccatcttg aaaatggtgc
    19321 gtcgtccaga gccagccgta gcagtagaag atgagaactt tttctttaag gtttccaagg
    19381 ctagttttac ccatcgccgc aagaccttgt ggaataactt gacaggttac tttggtaaga
    19441 ctgaagaggt caaggacaag ctgaccaagg ctttggacca ggcaggcttg tcaccaagtg
    19501 tgcgtgggga agctctcagc ttggcagaat ttgccggtct agcagacgca cttaaagggc
    19561 aaggactcta agatgcaggg acaaatcatt aaagccttgg caggtttcta ctatgtggag
    19621 agtgatggcc aggtttatca aacacgcgcg cgtgggaatt tccgtaaaaa aggccatacc
    19681 ccttatgttg gggactgggt agatttctct gccgaggaaa attcagaagg ctatatcctc
    19741 aaaattcacg aacggaaaaa cagtctggtc cgtccgccta ttgtcaatat cgatcaagct
    19801 gtagtaatca tgtccgtcaa ggaacctgat tttaacagca atttgctgga tcgtttcttg
    19861 gttcttttgg agcacaaggg catccatccc attgtctata tttccaaaat ggatttgttg
    19921 gaagataggg gagaactgga tttttaccgg cagacctatg gtgacatcgg ctatgacttt
    19981 gtgaccagta aagaggaact cctgtctttg ttaacaggca aggttacggt ctttatgggg
    20041 cagacaggtg ttgggaagtc aactcttctc aataaactcg taccagacct caatcttgaa
    20101 acgggagaaa tttcagacag tctaggtcgc ggtcgccata ccactcgagc tgttagtttt
    20161 tacaatctca acgggggtaa aatcgcagat acaccaggct tttcatctct ggactatgaa
    20221 gtatcaaggg ctgaagacct caatcaggct ttcccagaga ttgctactgt tagccgagat
    20281 tgtaagttcc gtacttgtac ccatacccat gagccgtctt gtgccgtcaa accagctgtt
    20341 gaagagggtg ttattgcaac cttccgtttt gataattacc tgcaattcct tagtgaaatt
    20401 gaaaatcgta gagaaaccta taaaaaagtc agcaaaaaaa ttccaaaata aggagaaacc
    20461 tatgtctcaa tacaagattg ctccgtcaat tctggcagca gattatgcca actttgaacg
    20521 tgaaatcaaa cgtctagaag caactggggc agaatatgcc catatcgata tcatggacag
    20581 tcattttgta ccgcaaatca gttttggtgc aggtgtggtc gagagccttc gtcctcatag
    20641 taagatggtt ttcgattgcc acttgatggt gtcaaaccct gagcatcatc tggaagattt
    20701 tgcgcgtgca ggtgcagaca tcatcagtat ccatgtagaa gcaacacctc atattcatgg
    20761 cgccctccaa aaaattcgtt tactcggagt taagccttca gtcgttatca atcctggcac
    20821 accagttgaa gccatcaagc acgtccttca tctagttgac caagttttag tcatgacggt
    20881 taatccaggt tttggtgggc aagcctttct gccagaaacc atggataagg ttcgtgagtt
    20941 ggttgctctt cgtgaggaaa aaggtttgaa ctttgaaatc gaagtggatg gtgggattga
    21001 tgaccaaact attgctcaag ccaaagaagc tggtgcgact gtttttgtag caggttccta
    21061 tgtctttaag ggagaagtca atgagcgagt acaaactctc agaaaacaac tggactaggg
    21121 ttgccgtttt tgcaggcgga aaccgcggtc attatcggac agattttgat gcttttgttg
    21181 gggtggatcg aggctcgctc tgggtcttgg aagaagactt acctcttgct ctagcagtcg
    21241 gagattttga ttctgtgacg gaagaagagc gacaggtgat tcaaaaacgt gcccagcatt
    21301 ttgtccaagc ccgaccagaa aaggatgata cagatctgga attggctctc ttaaccatct
    21361 ttgaacaaaa tcctcaggct gaggtcacta ttttcggtgc cttgggtggc cgtattgacc
    21421 atatgttggc caatgtcttt ctacctagca atcctaagtt ggcaccctat atgcgtcaaa
    21481 tagaaattga ggatgggcaa aatttgattg cctattgttc agaagggacc agtcagctag
    21541 aacctcgttc agactacgac tatctagcct ttatgccagt tcgggatagc cagctgacta
    21601 ttcttggagc taagtatgag ttgacagagg agaatttttt ctttaaaaaa gtgtacgctt
    21661 ctaacgaata tatagatagg gaagtgtcgg tgacttgccc agatggttat gtggtcgtac
    21721 tgcatagcaa ggacaggagg taggatggaa agtttactta ttctattatt aattgccaac
    21781 ctagctggtc tctttctgat ttggcaaaga caggataggc aggagaaaca cttaagtaag
    21841 agcttggagg atcaggcaga tcatttgtca gaccagttgg attaccgctt tgaccaagcc
    21901 agacaagcca gccagttaga ccaaaaagat ttggaagtgg ctgtcagcga ccgtttgcaa
    21961 gaagtgcgga ttgaattgca ccaaggcctg acccaagtcc gtcaagaaat gacagataat
    22021 ctcctccaaa ctagagacaa gacagaccaa cgtctccaag ccttgcagga atcaaatgag
    22081 caacgtttgg aacaaatgcg ccagacggtc gaggaaaaac tagaaaagac cttgcagaca
    22141 cgcttacaga cttcctttga gacagtttct aaacaactgg agtctgtcaa tcgtggtctt
    22201 ggagaaatgc agacagttgc ccgtgatgtc ggagctctta acaaggttct ctctggaacc
    22261 aagacgcgag ggattctggg agaattgcaa ctggggcaaa ttattgaaga catcatgaca
    22321 cctgcccagt acgaacgaga atacgcaacg gttgaaaact ctagtgaacg agtggagtat
    22381 gccatcaagt tacccggaca aggcgaccaa gaatacgtct acctaccaat tgactctaag
    22441 tttccactgg cagattatta ccgcttagaa gaagcctatg aagtaggtga caaggatgaa
    22501 atcgaacgct gtcgtaagtc actcctagca agtgtcaagc gttttgctag ggatattagg
    22561 aacaagtaca tagcaccacc tcggacgacc aattttggag ttttgtttgt tccgacagaa
    22621 ggtctctact cagaaatcgt ccgcaatccg gtcttctttg atgatttgag acgggaagaa
    22681 cagattatcg ttgcaggacc aagtacccta tcagcccttc ttaactccct atcagttggt
    22741 ttcaagaccc ttaatatcca aaagagtgcc gaccatatca gcaagactct tgccagtgtc
    22801 aagaccgagt ttggcaagtt tggtggtatt ctggtcaagg cacaaaaaca tctccaacat
    22861 gcctctggca atattgatga attattaaac cgtcgtacca tagctatcga gcggacgctc
    22921 cgtcacattg agttgtcaga aggcgagcct gcgcttgatc tactccattt tcaagaaaat
    22981 gaggaagaat atgaagatta gtcacatgaa aaaagatgag ctatttgaag gcttttacct
    23041 aatcaaatca gctgacctga ggcaaactcg agctgggaaa aactacctag cctttacctt
    23101 ccaagatgat agtggcgaga ttgatgggaa gctctgggat gcccaacctc ataacattga
    23161 ggcctttacc gcaggtaagg ttgtccacat gaaaggacgc cgagaagttt ataacaatac
    23221 ccctcaagtc aatcaaatta ctctccgcct gcctcaagct ggtgaaccca atgacccagc
    23281 cgatttcaag gtcaagtcac cagttgatgt caaggaaatt cgtgactaca tgtcgcaaat
    23341 gattttcaaa attgaaaatc ctgtctggca acggattgtc cgaaatctct acaccaagta
    23401 tgataaggaa ttctactcct atccagctgc caagaccaac caccatgcct ttgaaacggg
    23461 cttggcttat catacggcga ccatggtacg tttggcagac gctattagcg aagtttatcc
    23521 tcagctcaat aagagcttac tctatgcggg gattatgctg catgacttag ctaaggttat
    23581 cgagttgacg gggccagacc agacagagta cacagtgcga ggtaatcttc ttggacatat
    23641 cgctctcatt gatagcgaaa ttaccaagac agttatggaa ctcggcatcg atgataccaa
    23701 ggaagaagtc gttttgcttc gtcatgtcat cctcagtcac cacggcttgc ttgaatatgg
    23761 aagtccagtc cgtccacgta ttatggaggc agagattatc catatgattg acaatctgga
    23821 tgcaagcatg atgatgatgt caacagctct ggctttggtg gataaaggag agatgtccaa
    23881 taaaatcttc gctatggata atcgttcctt ctataaacca gatttagatt gataatttaa
    23941 gaaaaatgag cattttttag gataagaatg ttcgtttttt tatgtgaata tggtataata
    24001 agtaaaagac aaaaatgaat actcttcgaa aatctcttca aactagggta gtatcgcttt
    24061 gtcgtatgta tatatgcagg tatattacag ggtttgtcag ttctattgac aatctcaaaa
    24121 cagtgttttg aaccaccagc gaccagcttt ctagtttgct ttttgatttt ttgaataaaa
    24181 atggaatagg aaatagaaat gaaattaaga agaagtgatc ggatggttgt catttccaac
    24241 tatttgatta ataatcctta taaactaact agtctcaata cttttgctga aaagtatgag
    24301 tctgctaaat catccatctc agaagatatc gtcattatca aacgcgcctt tgaggaaatt
    24361 gaaatcggtc atatccagac agtgactggg gctggcggag gtgtcatctt cacaccgtct
    24421 atttcgagtc aggatgctaa ggaaatggtt gaagacttgc gtaccaagtt gtcagaaagt
    24481 gaccgtatct tgccaggtgg ttatatctat ctgtctgatt tgcttagcac accagccatc
    24541 ttgaaaaata ttggtcgtat tattgccaaa agctttatgg accaaaaaat tgacgcggtt
    24601 atgaccgtag caactaaggg tgtgccactt gcaaatgcag ttgccaatgt cctcaatgtc
    24661 tcttttgtca ttgtgcgccg tgacctgaaa attaccgaag gttcaactgt tagcgtcaac
    24721 tatgtttcag gttcaagtgg tgaccgtatc gagaaaatgt tcctttcaaa acgtagtctt
    24781 aaggcaggca gccgtgtctt gattgtggat gacttcttga aaggtggcgg aacggtcaac
    24841 ggtatgatta gtctcttgcg cgagttcgac tcagaactgg caggtgtagc ggtctttgcg
    24901 gacaatgccc aagaagaacg tgaaaagcag tttgactaca agtcactctt gaaggtaact
    24961 aatattgatg tcaagaacca agccatcgat gttgaggttg gcaatatctt tgacgaagat
    25021 aaataagaga tagaactaaa ggttggaacg attgtcccag cctttctttg caaacagaat
    25081 agaaggaagc ttatgaaaac accatttatc aatagagaag agttagaagc gattgttgcc
    25141 gagttcccga ctccctttca cttgtatgat gagaagggga ttcgtgagaa ggcaagagct
    25201 gtcaaccaag ctttttcgtg gaacaagggc tttaaggaat attttgcagt taaggctact
    25261 ccaactccag ctattttgaa aattctccaa gaagaaggtt gtggtgtgga ctgctctagt
    25321 tatgtagagc ttttgatgag ccataaactg gactttctgg gttctgagat tatgttctct
    25381 tccaacaaca cgccagacaa ggaatacgcc tatgcacgtg aattgggtgc gaccattaac
    25441 ttggatgcct ttgaagatat tgaacatctg gagagagtag caggcattcc agaaatcatc
    25501 tcttgtcgtt ataatcctgg aggcgttttt gaactgggga cagacattat ggacaatcct
    25561 ggggaggcta agtttggcat gaccaaggac cagctctttg aagcctttgc tatcttgaag
    25621 gaaaaaggag ccaagacttt tgggcttcac tccttcctag cgtccaatac cgtgacccat
    25681 ctctattatc cagagttggc tcgtcagctc tttgaactgg ctgttgaaat caaggaaaag
    25741 ttgggcattt cgttagactt tatcaatctt tctggcggta ttggtgttaa ttatcgtcca
    25801 gaccaggagc cgaacgatat cgccttgatt ggtgagggag ttcgtaaggt gtatgaagaa
    25861 gttcttacgt cagcaggtct tggtcaggtc aagattttca ccgaattggg tcgttttatg
    25921 ctggcacctc acggtgctct agtcacaaga gtcactcata agaaggaaac ctaccgtacc
    25981 tatctaggtg tagatgcctc agcagtcaac ctcatgcgtc cagctatgta cggagcttac
    26041 catcatatta gcaacgtgac ccatccagat ggaccagctg aagcggtaga tgtggttggt
    26101 tcactctgtg aaaacaatga taaatttgca gtcaatcgcg aactgcctca tacagaaatc
    26161 ggtgatttgc tggtaattca tgatacaggt gcccacggat tttcaatggg ctaccagtat
    26221 aatgccaaat tacgttctgc ggaaatcctc tataccgaag aaggtaaagc ccgtcaaatc
    26281 cgccgtgcag agcgccctga ggactatttt gcaaccttat atggcttcga ttttgaagaa
    26341 taatctgata atagattgaa aatgaaattg aaaaacagat tgctttctaa aaaataggca
    26401 aaaatcttgt ttttccttca agtcgtgata taataaaact ataaaacgtt ttcaaggaag
    26461 gtaacgatat gtctgaagaa acaattgatt atggacaagt gacaggaatg gtgcattcga
    26521 cagaaagctt tgggtcagta gatgggcccg gtattcgctt tattgtcttt ttgcagggct
    26581 gtcacatgcg ttgccagtat tgccacaacc cagacacttg ggctatggag tccaataagt
    26641 cacgtgaacg gacggtagat gatgtcttga cagaggcctt gcgctaccgt ggtttctggg
    26701 gaaataaggg tgggattaca gtcagtggag gagaagctct cttgcagatt gatttcctga
    26761 ttgccctctt caccaaggct aaggaacaag gaatccactg taccttggac acttgtgctc
    26821 ttcctttccg taataaacca cgttaccttg agaagtttga caaactcatg gctgtcactg
    26881 acttggttct tttggatatc aaggaaatca acgaagaaca gcacaagatt gtcactagcc
    26941 aaaccaataa aaatatcttg gcttgtgccc agtatctatc agatattgga aaacctgtct
    27001 ggattcgcca cgtgctagtt ccaggattga cagacagaga tgatgacttg attgaacttg
    27061 gtaagttcgt caagaccctc aaaaatgttg ataagtttga aattctacct tatcacacca
    27121 tgggtgagtt caagtggcgt gaacttggaa ttccatattc cctcgaagga gtcaaaccac
    27181 caacagcaga tcgcgtcaag aacgctaaac aactcatgga taccgaaagt tatcaagatt
    27241 atatgaaacg tgtacatgga tagaaaagaa gcctgatgga aacatcgggc ttttgacttg
    27301 caaaaagact tagcaaatca gctaagcctt tttcttctta tctcgaacgt tgttttccag
    27361 cgttgcgatt tttgtgtttt ttcttgcttg taatagcagt tggttgttca ggggtaacgt
    27421 cttttcgtcc acttggtgtt gagaaagcac ttgcttttgg tgggttcttt gccagttctt
    27481 cacggacttt tttgcgaagt tttggacgaa cgatatagtt gacgataaac tgttggagaa
    27541 tcatcatgaa accaccgaca acccagtaaa gtgtgacact agctggtgag aagagggaga
    27601 agacgacgat catgagtggg ctcatgtaaa tcattttctt gatttgttct ctttgcattt
    27661 catcttctac tccgtgaagt gaaaggagcg attgaagata gtaaaggaca ccagcacagg
    27721 caaccaaaat catacttgga gaacctagag gaatgcctag gtagcttgct tgagcaaccc
    27781 cttcagtatg ttgggcagca aagtagatag cagagaagaa aggcatttga aggaggagag
    27841 ggaaacatcc tacaccgcca aacatgctga taccgtgctc tttttgagca gcaaagagag
    27901 cttgttgggc ttcgagtttt tcttcttgag tagtcgcttc tttgagacgc gtttggtgtg
    27961 gctcaaggac gtgcttgagg gcgttcatct tttcagagtg aagcgttgcc ttccatgatt
    28021 ggtagatacc aagtggtaag ataattaagc gtacgataat ggttacgata atgatagcga
    28081 caccaaagcc tagaccttta tcagtagcga agtacttgat ggcttcagcc ataggcgctc
    28141 cgatggtatt ccaaataaat cctgttggct gacctgtggt tttatcgaca ttgacacagc
    28201 cagtcaagac aagcaacata gccactccca tagccgagaa tgcaaaacgt ttaatagatt
    28261 tcactgtttt tattccttct ttaaaaatta tacctttcta ttctactgtt tttttacaaa
    28321 atatacaata gttctggaga cctaatttgc gattttaaag tcagagtagg gaggaaagtt
    28381 gcttagtttg acatctaagt agcttacttt tgaaaaaggt gtcggtcctt ttcggatttc
    28441 ttggataaat tttgccatga tagcagatga gtctgcttgg gctaagattt ccactgtgcc
    28501 atcgtcgtta ttccatactc gacctgtgat gccaccaatt tcaagtgcca agctgtaaac
    28561 accccaacga aagccgactc cctgtaccct accttgggca atcattctaa ccttttgcat
    28621 accaaacccc tttgattgtg ttataatatt tctatgacta ttataacctc aaaagccaat
    28681 tctgtggtaa aaaatgccaa gaaattacac caaaaaaaat accgcaagtc tgcctatttg
    28741 attgaaggct ggcacttgtt tgaagaggct gtccaagctg gagtgacgat tgagaaaatc
    28801 tttgccctag aaaattatcg agatcagtta gctgcttttc cgcaaactgt ctggatttca
    28861 gaggatattt tgctagattt ggcggattct cagactccac agggaattgt ggcggtggtt
    28921 caaaaagaag aagtaggaca agctgatttg agtcagggca agttcttgtt tttggaagat
    28981 gtgcaagatc ctggtaatgt aggaactatc attcgaactg cggatgcagc aggttttaca
    29041 ggagtgattg tttcagataa gtcggcagac atctacagtc tcaaaaccct acgttccatg
    29101 caaggtagtc atttccatct gcccatttac cggatgacta gtcaagcgct tcttgacgaa
    29161 actaaaaagg tagctatccc agtgctagca acaaccctat ctaaagattc tgttgattac
    29221 agagaactgc cttctataga aaattttgta ctagttatgg gaaatgaggg tcaaggaatt
    29281 agtcccctta tggctgaaag tgcagaccag ttggtccata ttagcatgaa ggggcaggcc
    29341 gagagtttga atgttgcagt tgcagccggt attttaatct tccatttaag ctaattttaa
    29401 ctttttttgt tataatcaag gaaagatgtt cacagaaaag gagaaaagga tgaatcacac
    29461 tattatacat gaccgtgcag gtctcaatca attttacgct aaggtttatg cctttgttgg
    29521 tctgggaatc ggactatctg ctttggtatc aggccttatg ttgacggtct ttcagtctca
    29581 gttggtttac ttgttgatgc aggggcgtct ctggttgacc attgctactt ttgcggagtt
    29641 ggctttggtt ttcgttgcca gtagtatggc ttcaagaaat agtccagctg ctcttccagt
    29701 atttttactt tactccgttt taaacggctt tacccttagt tttgtggtgg ctttctatac
    29761 tccgggtaca gttttatctg cctttgtatc gagcgccctt ctcttctttg tcatggcggc
    29821 agttggtatc tttaccaaga aagacttgag tgggattggt cgagcaatga tggcagctct
    29881 cattggttta ctgattgcta tggtagtcaa tattttcttg gctagtggct tctttgatta
    29941 tatgattagc gtagccatgg ttttggtttt ttcagggttg attgcttggg ataaccaaaa
    30001 gattcgcctc gcctatgaac aatcacaagg tcgtgtagcg acaggctggg tggtgtcaat
    30061 ggctctcagc atctatcttg attttatcaa tcttttccta agtattctac gtatctttgg
    30121 tcgcaatgac taaaaggtct atgaaatcag tgttttgagt gacactgatt tttttttaaa
    30181 ttttctcttt tcttttcttg gaaataggtg tataatacgt ttattaaatt tttgaggagt
    30241 tgtctatgaa gaaaagtttt atccatcaac aagaagaaat ttcctttgtc aaaaacactt
    30301 ttacccagta tttgaaagat aagctagaag ttgtcgaagt tcaaggtcct atcttgagta
    30361 aggtcggtga cggaatgcag gacaacctgt ctggtgtgga aaatccagta tcggtcaagg
    30421 ttctccaaat ccctgatgct acttatgaag tggtgcactc acttgctaaa tggaaacgcc
    30481 acaccttggc tcgttttggc tttggtgaag gagagggtct ctttgtccac atgaaagccc
    30541 ttcgtccaga tgaggattcc ttggatgcaa cccactctgt ttatgttgac cagtgggact
    30601 gggagaaggt tatcccaaat ggtaagcgta acatcgttta tctaaaagaa acagttgaga
    30661 agatttataa ggctattcgc ctgactgagc tagctgttga agcccgctat gacatcgagt
    30721 ctatcttgcc aaaacaaatc acctttatcc atacagaaga attggtagaa cgctacccag
    30781 acttgacacc gaaagaacgt gaaaatgcga tttgtaaaga atttggagcc gtctttttga
    30841 ttggtatcgg tggcgagttg ccagatggta aaccgcacga tggacgtgca ccagactatg
    30901 atgactggac aagcgagtct gagaatggct acaagggtct aaatggtgat attcttgtct
    30961 ggaatgagtc tttaggtgga gcctttgagt tgtcttctat gggaattcgt gtagatgaag
    31021 aaactcttag acgtcaggtg gaaattacag gtgatgaaga ccgcttggaa ttggaatggc
    31081 acaagtcttt gttgaatggc ctattcccat tgacaatcgg tggaggaatt ggacaatctc
    31141 gtatggccat gttcctactt cgcaagagac acatcggaga agtgcaaaca agtgtttggc
    31201 ctcaagaagt ccgcgatact tacgaaaata ttttgtagag aatcgaaccg caaggttcgg
    31261 ttttctttct ctttttgtct ataatttggt ataataaaca gtatgaaaat catatcagga
    31321 atctatgggg gacgtcccct taagacacta gaaggcaaga caacaagacc tacttcggat
    31381 aaggttaggg gagccatttt taacatgatt ggtccctact ttgaaggggg acgagtcttg
    31441 gacctttatg caggtagtgg tggtttatct atcgaagcag tatcgcgtgg catgtccagt
    31501 gctgttttgg tggagcgaga ccgtaaggct cagaccatcg tggctgaaaa tatccagatg
    31561 accaaggaag ttggaaaatt tcaactcctc aaaatggatg cagaaagggc attggaacag
    31621 gtatctgggg aatttgacct cgttttctta gaccctccct atgccaagga acaaatcgta
    31681 gcagatattg aaaaaatggc tgagagagag cttttttctg aagatgttat ggttgtgtgc
    31741 gagacggata aagccgttga acttccagaa gaaattgcct gtctgggtat ctggaaggaa
    31801 aagatttatg gaattagtaa ggtgacagtc tatgtcagat aagattggct tattcacagg
    31861 ctcatttgat ccgatgacaa atgggcatct ggatatcatt gaacgggcga gcagactttt
    31921 tgataagctt tatgtgggta ttttttttaa tccccacaaa caaggatttc tccctcttga
    31981 aaatcgtaaa cgggggctag aaaaggcttt gggacatttg gaaaatgttg aagtcgtggc
    32041 ttctcatgat aaattggtgg tcgatgttgc aaaaagactg ggggctactt tcctagtacg
    32101 ggggttgagg aatgcggcgg atttgcaata tgaagctagt tttgattact acaatcatca
    32161 gctgtcttct gatatagaga ctatttattt acatagccgg cctgaacatc tctatatcag
    32221 ttcatcaggt gttcgagagc ttttgaagtt tggtcaggat attgcctgcc atgttcccga
    32281 gagtattttg gaggaaataa gaaatgaaaa aaaagattag atggcccttg tatgtcattg
    32341 cggccttgat tgtgaccttc ttggcatttg tggtgccttt gccctactat atagaggttc
    32401 caggtggttc ggaagatatt cgccaagtcc ttaaagtaaa tgacacagaa gataaggaag
    32461 ctggtgccta tcaattcgtt acggttggtg ttcaacatgc tactttagct catatgattt
    32521 atgcttggtt gacacctttt acagatattc gtagtgctca ggagactaca ggtggttctt
    32581 ccgatgttga atttatgcga atcaatcaat tctacatgca aacatcgcaa aatatggcca
    32641 agtatcaagg actaaaaaca gctggtaagg atatcgaact caagtacttt ggagtttatg
    32701 ttttgaatgt gacggataat tcaaccttta aagggattct caatatctct gatacagtca
    32761 cagcagtcaa tgatcagacc tttgatagtt ccaaagactt gattgattac gtcagttctc
    32821 aaaaattagg ggactccgtc aaggtcacct atgaagagga tgggcaaacc aagtctgcag
    32881 aaggaaagat tatcaccttg gaaaatggaa aaaatgggat tggaatcggc ttgattgatc
    32941 gtacagaggt aatcagcaat gtcccaatta gcttttcaac agctggtatt ggcggcccaa
    33001 gtgctggtct catgtttagt ctagctatct atactcaaat agctcaccca gatcttcgta
    33061 atggtcgtat tgttgccggt acaggtacca ttgaccgcga tggtaatgtg ggagacattg
    33121 gaggtattga taagaaggtt gtagcttcgg ctagggcagg tgctgctatt ttctttgctc
    33181 ctgataaccc tgttagcgaa gaagaacaaa aggcgcatcc ggacgcgaaa aacaactacc
    33241 aaacagccct agaagcggct aaaacaatca agacggatat gaaaatcgtg cccgttaaaa
    33301 ccctacaaga tgcgattgat tacttgaaaa acaatcccta atttttgagt gaagtttcca
    33361 aactagcgca caaacagaga agatggtata atagtcaaat ggttcaatta ttattcactc
    33421 taagtagtca tatgctcttt atttatgtga gtttttacct tttaaaggat cttgttagat
    33481 gggaaaaggt tttaaaagtg acagctgaga atacaagaaa agttcgtgta ttagtagcct
    33541 tttttagcat tgtcataggc tacatcctga gttctttctt tattagcctg tatcatttgt
    33601 ggcaagaagc gcttagagga ttattataaa atcaagagta aaggaaacga gtatggataa
    33661 aattgtggtt caaggtggcg ataatcgtct ggtaggaagc gtgacgatcg agggagcaaa
    33721 aaatgcagtc ttacccttgt tggcagcgac tattctagca agtgaaggaa agaccgtctt
    33781 gcagaatgtt ccgattttgt cggatgtctt tattatgaat caggtagttg gtggtttgaa
    33841 tgccaaggtt gactttgatg aggaagctca tcttgtcaag gtggatgcta ctggcgacat
    33901 cactgaggaa gccccttaca agtatgtcag taagatgcgc gcctccatcg ttgtattagg
    33961 gccaatcctt gcccgtgtgg gtcatgccaa ggtatccatg ccaggtggtt gtacgattgg
    34021 tagccgtcct attgatcttc atttgaaagg tctggaagct atgggggtta agattagtca
    34081 gacagctggt tacatcgaag caaaggcaga acgcttgcat ggtgctcata tctatatgga
    34141 ctttccaagt gttggtgcaa cgcagaactt gatgatggca gcgactctgg ctgatggggt
    34201 gacagtgatt gagaatgctg cgcgtgagcc tgagattgtt gacttagcca ttctccttaa
    34261 tgaaatggga gccaaggtca aaggtgctgg tacagagact ataaccatta ctggtgttga
    34321 gaaacttcat ggtacgactc acaatgtagt ccaggaccgt atcgaagcag gaacctttat
    34381 ggtagctgct gccatgactg gtggtgatgt cttgattcga gacgctgtct gggagcacaa
    34441 ccgtcccttg attgccaagt tacttgaaat gggtgttgaa gtaattgaag aagacgaagg
    34501 aattcgtgtt cgttctcaac tggaaaatct aaaagctgtt catgtgaaaa ccttgcccca
    34561 cccaggattt ccaacagata tgcaggctca atttacagcc ttgatgatag ttgcaaaagg
    34621 cgaatcaacc atggtggaga cagtttttga aaatcgtttc caacacctag aagagatgcg
    34681 ccgcatgggc ttgcattctg agattatccg tgatacagct cgtattgttg gtggacagcc
    34741 tttgcaggga gcagaagttc tttcaactga ccttcgtgcc agtgcggcct tgattttgac
    34801 aggtttggta gcacagggag aaactgtggt cggtaaattg gttcacttgg atagaggtta
    34861 ctacggtttc catgagaagt tggcgcagct aggtgctaag attcagcgga ttgaggcaag
    34921 tgatgaagat gaataagaaa tcaagctacg tagtcaagcg tttactttta gtcatcatag
    34981 tactgatttt aggtactctg gctctaggaa tcggtttaat ggtaggttat ggaatcttgg
    35041 gcaagggtca agatccatgg gctatcctgt ctccagcaaa atggcaggaa ttgattcata
    35101 aatttacagg aaattaggct ggagaaccag cctttttcta aagataagga gaaatatgaa
    35161 caaaaaaaca agacagacac taatcggact gctagtgtta ttgcttttgt ctacagggag
    35221 ctattatatc aagcagatgc agtcgacagc taatagtcct aaaaccaagc ttagtcagaa
    35281 aaaacaagcg cctgaagctc ctagtcaagc attggcagag agtgtcttaa cagacgcagt
    35341 caagagtcaa ataaagggga gtctggagtg gaatggctca ggtgctttta tcgtcaatgg
    35401 taataaaaca aatctagatg ccaaggtttc aagtaagccc tacgctgaca ataaaacaaa
    35461 gacagtgggc aaggaaactg ttccaaccgt agctaatgcc ctcttgtcta atgccactcg
    35521 tcagtacaag aatcgtaaag aaactgggaa tggttcaact tcttggactc ctccaggttg
    35581 gcatcaggtc aagaatctaa agggctctta tacccatgca gtcgatagag gtcatttgtt
    35641 aggctatgcc ttaatcggtg gtttggatgg ttttgatgcc tcaacaagca atcctaaaaa
    35701 cattgctgtt cagacagcct gggcaaatca ggcacaagcc gagtattcga ctggtcaaaa
    35761 ctactatgaa agcaaggtgc gtaaagcctt ggaccaaaac aagcgtgtcc gttaccgtgt
    35821 aaccctttac tacgcttcaa acgaggattt agttccctca gcttcacaga ttgaagccaa
    35881 gtcttcggat ggagaattgg aattcaatgt tctagttccc aatgttcaaa agggacttca
    35941 actggattac cgaactggag aagtaactgt aactcagtaa aagataagcc taaactccta
    36001 tgtcacttat ggatgtagga gttcttttta ctagtttaag cagggctaga acaggtgcta
    36061 agaaaaaata gtaacttcta aaactaactt ccagtttccc acaacctagc ttttagtatg
    36121 agaaaaacgc gtgaaatcag tggaaatccg tcttagacta acttccagtt ttgggagaga
    36181 gatggaagtt acgctaagaa aaaaataata tgtattggat taaattttgt gatataataa
    36241 aggataagat actattttag gagaagaact atggaagacc caagtagtca gaatttgttg
    36301 ctacaatttg ttttattgtt tatcttgacg gtattaaatg cctttttctc agccacagaa
    36361 atggccatgg tttctcttaa tcgtgcccga gttgaacaaa aagcggaaga aggagacaga
    36421 cgctacattc gcctgctgaa ggtactagaa aatcctaacc actttttatc aaccattcag
    36481 gtaggaatca ccctgattac aatcttatca ggggcgagtt taactgatac tctaggacgt
    36541 gtgattgcct cttggcttgg gaatggcgaa acagcacaag ccgtggcaac ttttctatcc
    36601 ttggcatttt tgacctatat ttccatcgtt tttggggaat tatatcctaa gagaatcgct
    36661 cttaatctaa aggatgcctt ggcaattcgt acagcgccgg ttatcattgg gatcggaaaa
    36721 ctagtcagtc cttttgtttg gcttttagct gcttcgacca atttcttgag ccatttgact
    36781 cctatgtcat tcgatgatgc ggatgaaaag atgacccgtg atgaaattgc ctatatgctg
    36841 acaaatagtg aagaaacatt ggatgctgat gagattgaga tgctacaagg tgtcttttcg
    36901 ctcgatgaac tgatggcacg agaggttatg gttcctcgaa cggatgcctt tatggtggat
    36961 attcaggatg atagtcaagc cattatccaa agtattttaa aacaaaatta ttctcgtatc
    37021 ccggtttatg atggggataa ggacaatgta attggaatca ttcacaccaa gagtctcctt
    37081 aaggcaggct ttgtggacgg ttttgacaat attgtttgga agagaatttt acaagatcca
    37141 ctttttgtac ctgaaactat ttttgtggat gacttgctaa aagaactgcg aaatacccaa
    37201 agacaaatgg caatcttgct ggatgaatac ggtggtatgg ctggtttagt gactttggaa
    37261 gacctcttag aggaaattgt tggtgaaatt gatgatgaaa cggacaaagc agcaatagat
    37321 gttcatcaga ttggcgagga tacctacatt gttcaaggaa ctatgaccct caatgatttc
    37381 aataattact ttgatgttga actggaaagt gatgacgttg ataccatcgc tggttattat
    37441 ttgacaggag tgggaaccat tccaacgact gagaaactca gctatgaatt ggtcagccaa
    37501 aacaaacagt ttatcttaac caatgataaa gtgaagaatg gacgtgttac caaggtaaaa
    37561 gtccaaatca cagaagtcga aatagaagaa gaaacagaat aaactagagg cttttgtcac
    37621 caggcgtgac gaagcttttt tcaattgatt tcaaaaggga attatgccat ggaaagaact
    37681 ctgccacaaa ctcgctccaa aagtttttaa agttatacgt atttattcga gggaaaataa
    37741 gaaaagccct tcaaattggg ctttctgttc atttgaaacc tgataaatca agttatagaa
    37801 ggcggtagac ggatttgaac cgacgatcaa gcttttgcag agccgtgcct taccacttgg
    37861 ctataccgcc ttaacgttta ttattatacc ttgaaaatga ttttcagtca atagtttttt
    37921 cagttttttg taccatagcg tgattcgaat gtgatgccaa gttttctatg ggaaaaaaat
    37981 taccaaaaac ctactgaatc cccttgaaaa atctagctaa atagggtata atatgggtaa
    38041 tcatttgtcg taggttttgt ctgaaatatt gtccagacaa ggctcacagc agttaaatct
    38101 tctgaaaaag tcagatttag ctgctctttt tgtgcttttt ttcaagattt tgagcatttg
    38161 taacagaggc ttaaagattc tgaaaattcg tcaagaggac acggtgataa ggggtttaca
    38221 accatatggc gattagaaaa gcctgattga caaggcttgg aacttattta caaaggagaa
    38281 tcatcttggc aggacatgac gttcaatacg ggaaacatcg tacccgtcgt agtttttcaa
    38341 gaatcaaaga agttcttgac ttaccaaatt tgattgaaat tcaaactgac tcattcaaag
    38401 ctttcctaga ccacggtctt aaggaagtgt ttgaagatgt attgccaatt tcaaacttca
    38461 cagacacaat ggagttggaa tttgttggat atgaaatcaa ggaaccaaaa tacacgctag
    38521 aagaagctcg tatccacgat gctagctact cagcaccaat ttttgtaacc ttccgtttga
    38581 tcaataaaga aacaggcgaa atcaagaccc aagaagtttt ctttggtgat ttcccaatca
    38641 tgacagaaat gggtactttc atcatcaatg gtggtgaacg tattatcgtt tctcagttgg
    38701 tccgctcacc aggtgtttac tttaacgaca aagtagacaa aaatggtaag gtgggctatg
    38761 gttcaactgt tatccctaac cgtggagctt ggttggaact tgaaagcgac tcaaaagata
    38821 tcacctacac tcgtatcgac cgtactcgta agattccatt tacaaccttg gttcgtgctc
    38881 ttggtttctc aggtgatgat gaaatctttg atatctttgg tgacagcgaa ttggttcgca
    38941 acactgttga aaaagatatc cacaagaatc caatggactc tcgtacagac gaagccttga
    39001 aagaaattta cgaacgcctt cgtccaggtg agcctaagac agctgaaagc tcacgtagct
    39061 tgcttgtggc tcgcttcttt gacccacgtc gctatgactt ggcagcagtt ggtcgttaca
    39121 aaatcaataa aaaactcaat gttaaaacac gtttgctcaa ccaaaccatt gcagagccat
    39181 tggtagaccc tgaaactgga gaaatcttgg tagaagctgg tacgattatg actcgtagcg
    39241 tgattgaaag cattgaaagc catttggatg gcgacttgaa caagattgtc tacatcccaa
    39301 acgatgcagc cgttgtgact gagcctgttg ttcttcaaaa attcaaggtt gttgctccaa
    39361 ctgatccaga tcgcgtcgta acgatcattg gtaatgctaa cccagatgac aaggttcgta
    39421 cggtgactcc tgcagatatc cttgccgaga tgagctactt cctcaacttg gctgaaggac
    39481 ttggccgtgt agatgatatc gaccaccttg gaaatcgtcg tatccgtgcg gttggtgaat
    39541 tgcttgccaa ccaagtacgt ttgggacttt ctcgtatgga acgtaatgtc cgtgaacgta
    39601 tgtctgttca ggacaatgaa gtcttgacac cacaacaaat tatcaatatc cgtcctgtaa
    39661 cagctgcagt taaagaattc tttggttcat cacagttgtc acagttcatg gaccaacaca
    39721 acccgctttc tgagttgtct cacaaacgcc gtttgtcagc cttaggacct ggtggtttga
    39781 ctcgtgaccg tgccggatat gaagtacgtg acgtgcacta cactcactat ggtcgtatgt
    39841 gtccaatcga gacacctgaa ggacctaaca tcggtttgat caataacttg tcatcttacg
    39901 gacacttgaa caaatatggt tttgttcaaa caccataccg taaggttgac cgtgaaacag
    39961 gtgttgtcac gaacgaaatt gtttggttga cagctgatga agaagatgaa tatactgtag
    40021 ctcaggctaa ctctcgtctg aatgaagatg gaacctttgc tgagaagatt gtcatgggac
    40081 gtcaccaagg ggtcaaccaa gagtatccag ctaatattgt tgactacatg gacgtttcac
    40141 caaaacaggt agttgccgtt gcgacagcat gtattccttt cttggaaaac gatgactcca
    40201 accgtgccct catgggagcc aatatgcaac gtcaggctgt gccattgatt aatcctcagg
    40261 caccttacgt tggtactggt atggaatacc aagcagccca cgattctggt gcggctgtga
    40321 ttgctcagta tgatggtaaa gttacttacg cagatgctga caaggtagaa gttcgtcgtg
    40381 aagatggttc attggatgtt taccacatcc aaaaattccg tcgttcaaac tcaggtactg
    40441 cttacaacca acgcactctc gtaaaagttg gtgatgtcgt tgaaaaaggc gatttcatcg
    40501 ctgacggacc ttctatggaa aatggagaaa tggcgcttgg acaaaaccca atcgttgcct
    40561 acatgacttg ggaaggttac aacttcgagg atgccgttat catgagcgaa cgcttggtga
    40621 aggacgatgt ctacacatct gttcaccttg aagaatacga atcagaaacg cgcgatacaa
    40681 agcttgggcc tgaagaaatc actcgcgaaa ttccaaacgt tggtgaagat gccctcaaag
    40741 accttgacga aatggggatt atccgtattg gtgctgaggt taaagaaggt gatattcttg
    40801 taggtaaagt aacacctaag ggtgagaaag atctttcagc tgaagaacgt ctcttgcacg
    40861 ctatctttgg agacaagtct cgtgaagtgc gtgatacttc tcttcgtgta ccacacggtg
    40921 ccgatggtgt cgttcgtgat gttaagatct ttacacgtgt aaatggagat gagttgcaat
    40981 caggtgttaa catgttggtt cgtgtttaca tcgctcaaaa acgtaagatt aaggtcggag
    41041 ataaaatggc cggacgtcac ggaaacaaag gggttgtctc tcgtatcgtt cctgtagaag
    41101 acatgcctta ccttccagac ggaactccag tcgacatcat gttgaaccca cttggggtgc
    41161 catcacgtat gaatatcggt caggttatgg agcttcacct tggtatggca gctcgtactc
    41221 ttggtattca cattgcgaca ccagtctttg atggagcaag ttctgaagat ctttggtcaa
    41281 ctgttaaaga agcaggtatg gatagcgatg ccaaaacgat cctttacgat ggacgtactg
    41341 gtgaaccatt tgataaccgt gtttctgttg gagtcatgta catgatcaaa ctccaccaca
    41401 tggttgacga taaattgcac gcgcgttcag tcggacctta ctcaactgtt acccaacaac
    41461 cactcggagg taaagctcag tttggtggac aacgtttcgg tgagatggag gtttgggctc
    41521 ttgaagccta cggtgcgtca aatgtccttc aagaaatctt gacttacaag tctgacgata
    41581 tcaacggacg tttgaaagcc tatgaagcta ttacaaaagg caaaccaatt ccaaaaccag
    41641 gtgttccaga atccttccga gttcttgtca aagaattgca atctcttggt cttgacatgc
    41701 gtgtcctaga cgaagatgac caagaagtgg aacttcgcga cttggatgaa ggaatggacg
    41761 aagatgtcat ccacgtagat gaccttgaaa aagcccgcga aaaagcagcc caagaggcta
    41821 aagcagcctt tgaagctgaa gaagctgaga aagcaacaaa agcggaagca acagaagaag
    41881 ctgctgaaca agaataagca gttcacttag aatagaaagg gaagaaatag tggttgatgt
    41941 aaatcgtttt aaaagtatgc aaatcaccct agcttctcca agtaaagtcc gttcatggtc
    42001 ttatggagaa gtcaaaaaac ctgaaacaat caattaccgt accttgaaac cagaacgtga
    42061 aggactcttt gatgaagtga tctttggtcc tacaaaagac tgggaatgtg cttgtggtaa
    42121 gtacaaacgc attcgttaca gaggaattgt ttgtgaccgc tgtggggttg aagtaacgcg
    42181 tacgaaagtt cgtcgtgagc gtatgggaca tatcgaattg aaagctcctg tatctcacat
    42241 ctggtacttc aaggggattc caagccgtat gggcttgacc cttgatatga gccctcgtgc
    42301 cctcgaggaa gttatctact ttgcggctta tgtggtgatt gatcctaagg atacaccact
    42361 tgagcacaag tctatcatga cagagcgcga ataccgagag cgcttgcgtg aatatggtta
    42421 tggttcattt gttgccaaga tgggtgcgga agccatccaa gaccttttga agcaagtaga
    42481 tcttgaaaaa gaaattgctg aactcaaaga agaattgaaa acagctactg gacaaaaacg
    42541 tgtcaaagcc atccgtcgtt tggatgtttt ggatgccttt tacaagtctg gaaacaaacc
    42601 tgaatggatg attcttaaca tccttccggt tattccacca gatcttcgtc caatgttgca
    42661 gttggatggt ggccgttttg cctcatctga cttgaatgac ctttaccgcc gtgttatcaa
    42721 ccgtaacaac cgtttggctc gtttgcttga gttaaatgca ccaggtatca tcgttcaaaa
    42781 tgagaagcgt atgcttcaag aagcagttga cgctttgatt gacaatggtc gccgtggtcg
    42841 tccaatcaca ggaccaggta gccgtccatt gaaatcattg agccacatgc ttaaaggtaa
    42901 acaaggacgc ttccgtcaaa acttgctcgg taaacgtgtt gacttttcag gacgttccgt
    42961 tatcgctgtt ggtccaactc ttaagatgta ccaatgtggt gtgccacgtg aaatggcgat
    43021 tgaactcttt aaaccatttg tcatgcgtga aatcgttgcc cgtgatatcg tgcaaaacgt
    43081 caaagcagct aaacgcttgg tggaacgcgg agatgagcgt atctgggata tccttgaaga
    43141 agtgattaaa gaacacccag tgcttttgaa ccgcgcaccg acccttcacc gtttgggtat
    43201 ccaagccttt gagccagtct tgattgatgg taaggctctt cgcttgcacc cacttgtctg
    43261 tgaagcctac aatgctgact ttgacgggga ccaaatggcc atccacgtac cactttcaga
    43321 agaagcacaa gcagaagctc gtatcctcat gctagctgct gagcacatct tgaacccgaa
    43381 agatgggaaa ccggtagtta ctccatctca ggacatggtt ttgggtaact actacttgac
    43441 catggaagaa gctggtcgcg aaggtgaagg aatggtcttc aaagaccgtg acgaagcggt
    43501 tatggcttac cgcaatggct atgttcacct ccactcacgt gttggtatcg caacagacag
    43561 cctcaacaag ccttggacag aagagcaaag acataaggtc ttgcttacaa cagttggtaa
    43621 aattctcttc aacgatatca tgccagaggg gctaccatac ttgcaagaac caaacaatgc
    43681 caacttgaca gaaggtgttc cagctaaata cttcttgcca cttggtggag atatcaagga
    43741 agctatcagc aatcttgagc tcaaccctcc attcaagaaa aaaaaccttg gaaatatcat
    43801 cgctgaaatc ttcaaacgtt tccgtacgac agaaacttct gccctacttg accgcatgaa
    43861 gaatctcggt taccaccact caactcttgc aggattgaca gtgggtattg ccgacatccc
    43921 agtcgttgat gacaaggctg aaatcattga agaatcacac aaacgtgtcg aacaaatcac
    43981 caaacaattc cgtcgtggta tgatcacaga cgacgagcgt tacaatgctg ttacagctga
    44041 atggcgtgct gcccgtgaaa aacttgagaa acgcttgatt gctaaccaag atcctaagaa
    44101 cccaatcgtt atgatgatgg actctggagc ccgtggtaac atctcaaact tctcacagct
    44161 tgccggtatg cgtggtctga tggctgctcc gaatggacgt atcatggaat tgccaattct
    44221 ttcaaacttc cgcgaaggtt tgtcggtatt ggaaatgttc ttctcaactc acggtgctcg
    44281 taaaggtatg accgatacgg cccttaagac agccgactca ggttacttga ctcgtcgttt
    44341 ggtcgacgtt gcccaagacg ttatcatccg tgaggacgac tgtggaactg accgtggtct
    44401 cttgatccgt tctatcgcag aaggaaaaga gatgatcgag tctctcgaag agcgtctcaa
    44461 cggtcgttac actaagaaaa ctgttaaaca tccagaaact ggtgcagtga ttattggtcc
    44521 aaatgaattg attacagaag acaaggcgcg tgaaattgtc aatgctggtg tggaagaagt
    44581 gactatccgt tctgtattta catgtaacac tcgtcacggt gtctgccgtc actgttatgg
    44641 tatcaacttg gcgactggtg atgcggttga agttggtgaa gcagttggta caatcgctgc
    44701 ccaatctatc ggggaacctg gtacacagct tacaatgcgt accttccaca caggtggggt
    44761 tgcctcaaat accgatatca ctcagggtct tcctcgtgtc caagaaatct ttgaagcccg
    44821 caatcctaaa ggggaagcgg ttatcacaga ggttaaagga caagttactg ctatcgaaga
    44881 agatgcatca actcgtacca agaaagtctt tgttaagggt gaaactggcg aaggtgaata
    44941 tgtcgttcca tttacagctc gtatgcgtgt cgaagttggg ggccaagtag cgcgtggtgc
    45001 tgctctgaca gaaggttcta tccaaccaaa acgtctcctt gcagttcgtg atgtcttgtc
    45061 agttgaaacg taccttctcg gtgaagtaca aaaagtttat cgtagccaag gggtagaaat
    45121 cggtgacaaa cacatcgagg taatggttcg tcaaatgatc cgtaaagtcc gtgtcatgga
    45181 tccaggtgat acagatcttc tcatgggtac cctcatggat atcaatgact ttacagatgc
    45241 caacaaagat gtccttatcg caggtggagt tccagcgaca ggtcgcccag tccttatggg
    45301 aattaccaaa gcctcacttg aaacaaacag tttcttgtca gcggcttcct tccaggaaac
    45361 aactcgtgtc cttactgacg cagctatccg tggtaagaaa gaccatctcc ttggacttaa
    45421 agaaaatgtt atcatcggta agatcatccc agctggtact ggtatggccc gttaccgtaa
    45481 ccttgaacca catgctgtca acgaagaaga ataccttaat cctccagtag aggaagaagg
    45541 aaatgaagaa acaacagaag tagttgtgga tactgccgtt gaaactgtgg aagaaacagt
    45601 agaataagag agaatgagag aacccgaggg ttctctcatt ctctcttctg aaaactttct
    45661 ccatttttcc acgaaatgtg gtaaaataaa agaaagaagc tgacaaagga gacgggtatg
    45721 gaacaaacat tctttatcat caaaccagat ggtgtaaaaa gagggctagt gggtgaagtg
    45781 ttaaagcgca tcgaacaacg tggatttaca atcgaaaaat tggagtttcg ttcacaggtt
    45841 tcagaagagt tgattgacca gcactatcag gacttggttg gtcagagttt ttacccaccg
    45901 attcgtgaat tcatgacttc aggtccagtt cttgtgggtg tcatttctgg tcccaaagta
    45961 atcgaaactt ggcggaccat gatgggtgca actcgtccag aagaagcttt accaggcact
    46021 attcgaggtg attttgcaaa agctgctgga gaaaatgaga ttatccaaaa tgttgtacat
    46081 ggttcagatt cagaagagtc agctaagcga gaaattgctc tttggtttta agagtggatt
    46141 ggctcaatca attggttaaa agctcatttg aatagaaagt atagtcaatt agtttaagac
    46201 atgacgcatg atatcaaact ttttagtttt tgatatggtg cgttttttga ttaagtgact
    46261 attagtttgt ctcgctccgt taggtgcgag acaaaaaaac acccgctatg cgggtgcgcg
    46321 tcgaaggtta taccaaaaaa actccaaacg cgatacaata aaggtgttca atccaattgt
    46381 aaagcgaaag gagaaaaata tggcacaaaa ggttctttta tcctgttctt gtttcaattg
    46441 actatatttc tatacttttt cttcctttct ctgtgaaaat cgcaagtttt tcccaccttt
    46501 tctcaatact gaaacaacat ctttccagaa cttcaataat ttctttttgt gttaaatcat
    46561 tatttaacta aatctttgga ggcaatacgt tttcaaagct acttttttac cataggtttt
    46621 gagccttcaa cacagattac taagccaaaa atgctctaaa tttttgaaat tctaacaaat
    46681 tccactcaac tttatcatca tctttgactt tcacaatatc ttcctcaaaa taacatggaa
    46741 taaagatagt tttcttttaa aacggttgta ggaggaaaat ctctcctaca ctattattga
    46801 ttctgagaga aaattgcaaa atatcatcta ccaaactttc aattattaag attttttgca
    46861 gtttatctga attagaatcg caaggcttct caataatata attgtcgaat tttttcattc
    46921 taacttcctc tccattattt cttcctttat caagaaaaag ttacctcaat attaataaag
    46981 tacaattcta aattaactcc aattcttgat tcatgataat atttcagtaa ctcatcgtgc
    47041 aattaaaaac aaggattttt atttcagatg atccatcgtg aacacttcat cagccatctc
    47101 ccaaattgcc ggattatgtg ttgcgataat gattagccta ttatcatctc gaagagatag
    47161 caaaatctcc ataatcaact gagaggttgc tgggtctatt gaagctgttg gctcatctgc
    47221 cagaataaag ggtggattct ttaagataat ttttgccaag gcaacccgtt gcgattctcc
    47281 gcccgataac tcaaagatgc gcttatctag gtcaagataa accaggccga cctgttctaa
    47341 agcctgcttc tgcctcaacc gctgttccga ccgactcaac ttttgaccaa tgagacctag
    47401 cttaaggttt tcttcaatac tttggttttc aattaagcca aagttctgga agaggtagcc
    47461 caattcgtga cggaaaaaat cacttgattt ataattggcc aagtctttac ctcggtaaaa
    47521 aatcgtccca tcataaggtt ctaatttccc aatcatgttc atcaaggttg tttttccgct
    47581 accacttgaa ccaattaagg catagacttt tccagcctca aatgtcattg aaagattcga
    47641 aaataactct cgttctccaa aagatttact cacctgttta agttcaatca tattaacctc
    47701 ccttcaaaac aagcatggac atcttgtttt ctttctgcat ttggacatgt aactgtaaaa
    47761 gagatagacc agtaaagagt aacaagacta agaaagcaac tcctatttct acctgaagaa
    47821 atacactagc aacaaatccc agtaaaaaca cacccagttg agcaaagaga taagtgcgat
    47881 ggatttctaa gaacctgaga cctgcaatgc gtttgataaa aatggcacgt ctaaattctt
    47941 caaagtagag cctattcata gtgttaaaca gcaagattga agttgcaatc ccaagcacag
    48001 ctcctgctag cattacccaa cgttccctct ggatattatc caataatgtg atgtagttgt
    48061 ggtaacctgt ttgcatttct gagacccaat tttcaatgcc ttgtctctgg ataagctcct
    48121 gggcatcaga caattgatta aagagaacgt agttctgtac tgcgtctatc caaaacaaaa
    48181 tggactgtgg accagttgat tggggtgtta taacaatgat gattggatct ttcaaaaact
    48241 gctggtaaga aataggggtc gtattataca caaaacgatc ctgacctgat tctaaataac
    48301 ctaccgtagc agtcatttgc tgtcgttcat cttgactaga catgcgactg gttaagtcgt
    48361 cttcaaaaac agatttataa tgatcttcct ctgaacggag gtgttcaggc agcaataaga
    48421 caaactcccc tacatcaagg tgattcatct tttgctcaat agttgtatct acaggaatgt
    48481 tttgacgctc caagtattgc ggtgtgacga taaggacatt gccattcggg ctgtaatcgt
    48541 gccattctgt agaggttata aagtttttgg aggaagccat gccattttgc aaagtacggt
    48601 caattaactg gtgtctagat aagaaagcct tttgttctga aacagccaga tccatcaatt
    48661 gataccaagt tctgagtttc ctttgagctt gttcatcaaa accaggactc gttccttcac
    48721 ggctgattga tagggtaatc agttgccttt cctggctcca agcctcttgt ccaatccgat
    48781 gctgttgcca ggcttgggaa tactttaagc tactccctat tcccagtgtt acaataataa
    48841 tcgctaatag ttgaccgatt aaaatcaaac taatgattcc tctgacaggc acttgccctt
    48901 ttataatctg catcaggtgt atctttttta tcccaactgc gaagagttga gcgaaaaaca
    48961 gggagataga caacaagatg agattataac tgagcaagcc tgctcctatg gtcattaggg
    49021 attgcgttgg aagcgacaga attttttgca taagaatggt gagcacgcca gctaaactga
    49081 aaccaacagc tatccctttc aaatcctcac caactggtct aagaaaaatg gaccaccgtt
    49141 tctctcctga aatgaggcga atgcccgacg accgtaattg gctaatttga ctaattaaag
    49201 tcagtgctcc aaaggttaag atgaaaatca atagactgat taactgaaat ccgttactaa
    49261 agatagccat taacgtagat agtttagatg gaattgtcag gtgcatatta gtcaagccaa
    49321 gttgacttag ctcctccctt agcaagtgaa tatctaggtg tccatcgaat acaaaatagt
    49381 ttgtttcaac actactactt tgagcatctt ctagtttttt ttcctgtagc ccgtcaggca
    49441 actttccgtc tccaaaggtc gtataagaaa aaactgtagt accttctgag ttaggatctt
    49501 ggtgttgaat cgcaataaag ctatctgttt cttctgctag tttttccaag cgtgtagcaa
    49561 catgctgaaa agttgtttca ggggaagaat catgtacaac aacgttgggg taataatggg
    49621 agacatatgt atcagtccaa atggtaaata cccaaacaaa gaacaaacta gcaagcaggt
    49681 tggatatgag tataaataat tttttcatag tgcattcctt attctaaaac agagggcaga
    49741 aatacccctg ccctctataa actaacaagc ttactaaact attgataaaa gaatcttctt
    49801 caattattct ttaccatccc gcatcaaatg taattcgctc ccccaaattt gtattaacaa
    49861 acgcataggc cgcactatgt gctcctgcat aaactgtttt ttgattgtca cgttcattac
    49921 ttccaacata ggcccagtga tactgtgaac catgataata attcgaaaat gctccccaat
    49981 tatatggatc atgatggcct ccataggtcc actcgccacc acggtgagaa actgccaaaa
    50041 caggaagagc caaactaaat gccaaaacgg caagggatga tgcaactact tttctaaatt
    50101 ttaacatatt attactcctc taaatgaaat attatgaaaa tgagcgaaat gcaactacat
    50161 attttaatta gaaatctcag tctgaattat agtatcctat tttttcctcc tttctaactg
    50221 cacgttcctt tctacaggca gagacctaat tttataaacc aatcttaaat actttagatt
    50281 ttgtaactca taattttcaa cagttggtta gctatgaaag cattttatca aacatctcca
    50341 ttcttatatc tatctggtat tgttacaagc tctcatcaga atacctttct ctaaatagtt
    50401 gaattttaaa gtaatacgaa atcaatcagc cttcccaaca tcaagaccat tggacttctt
    50461 ttgtgattgc actcgaatct ccaattgtct attcttctga ataactgttg gtaaggaatt
    50521 gtgttactaa acataaaaac acctagtaat actaatatag ctaatttttg aattccacga
    50581 tttttcttca ttcgtgaaac ccctttcttt ttccttgttt ttattttaac atatatatat
    50641 tattcggtca agtattttta tgtaattttt gacttttttt atttattacc ataaagaatt
    50701 atttgtttct ttaacttact attttgaact aaaaatttta taatgaaatt aagcaaatag
    50761 gaaggtttat tatctttaat gaatacactc gcagagaaat tcagattgaa aagaaaagag
    50821 ttgagactct cccaacaaac tcttgcagaa ggaatttgtg aacaaagtca gattagtaaa
    50881 attgagagag ggcatttcat tccctccgca gaccttttgt tcaaactctc acaacgactt
    50941 gaagtaccat tagattattt ttttaatgaa caaattgaaa ttaaatctaa cctctctaat
    51001 ttcaagcaat tgtctgctcg actattagat gacagaaatt atgataattt ggaatatatt
    51061 tatagaattg agattgaacg aagtactttt ctaacactag aagaccgaac ttatcttgaa
    51121 tggattaaag ctattattga cttctatcaa tatgacagta agtgtgaggc aatttcttca
    51181 ttggaaaata tattattaaa agtctcttca aatactctga tttatttaaa ggcgttgaat
    51241 actctatcta atttctattc cttagtgggt cgtgaacaag aatatgaggc aaactactct
    51301 catttaatag agttgtatca gacaaaaaat ttggaccatc aagagttttt atttggctac
    51361 atcagagttc gttacaacta cgctcactac ctagtatcaa aggaaaaata taatgaagcc
    51421 atccaagaag ctcttgaaac gattgaactc tgtaaacaaa gacagacaag ctaccaattg
    51481 gctcctctac ttattcttgt aggaaatgct ggagccaaat ttctagacag agaacaagtc
    51541 aaaaattatt atatagaagc aagagagtta tgtaagattt ataacaatcc tttaatgttg
    51601 atgaagatag aaaattattt gaaggaatta gatactgttt agttaatctt gacattatag
    51661 tttttctgaa acgttaaata acctgtaagg ctgatagtta gattaatact atcagcctta
    51721 tcattatgtg actctgagtc cgtctcgctc cgtgaggtgc gagacaaaac aaccacccgt
    51781 ttgacggatt ttcatgattt caaatttata ttcttcgaaa atctcttcaa accacgtcag
    51841 ctctatctgc aatctcaaaa cactgttttg agcaacctgt ggctagctac ctagtttgat
    51901 ctttgatttt cattgagtat tagtctctag tgtttgttta gcgtcttaaa gagacatttg
    51961 agaagattag aaacagttct ctcttttctc ctagtataat gattggtagg aagggagaga
    52021 gaagatgaaa tcaatgagaa tcttattttt gttagcttta attcaaatca gtttgagtag
    52081 ctgtttccta tggaaggaat gcatcttgtc ctttaaacaa agtacagctt ttttcatcgg
    52141 aagcatggtt ttcgtttcag gaatctgtgc tggagtaaat tatctttata cccgtaagca
    52201 agaagtccat agtgtcctag ccagtaagaa gtcggtgaag cttttttaca gtatgttact
    52261 cttaattaat ttgttaggag ctgttcttgt tttgtcagat aacttgttca tcaaaaatac
    52321 gctgcagcaa gaattagttg actttttatt gccatccttc tttttcctat ttgggctaga
    52381 tttgctgatt tttttaccct tgaaaaaata cgtgcgcgat tttcttgcta tgctagacag
    52441 aaaaaagaca gtgttggtga ctattttagc aacacttctt ttcttaagaa atccaatgac
    52501 cattgtctca cttctgattt atactggact gggcttgttt tttgcagcct atcttgtccc
    52561 aaattcggtt aagaaggaag tttcctttta tggtcatatt ttccgagatc ttgtattggt
    52621 cattgttacg ctcattttct tttagagaaa gcctgttttt tatggatgtt atgatgataa
    52681 gtttagtagg aaaatagaca caaaagaaaa gtttttggta taataagagt atgtacacaa
    52741 aaaatgaaga agagttgcaa gccttagggg agcgtttggg ccatctatta gcaaagaatg
    52801 atgttttaat cttaattgga gaactgggtg caggtaaaac gacctttact aaaggacttg
    52861 caaaaggatt acagatttct caaatgatta aaagtcctac ctatactatc gtgagagagt
    52921 atgaaggtcg acttccactt tatcacctag atgtttatcg tattgaagga gatgctgatt
    52981 ctatcgactt ggatgagttt atctttggtg gcggcgtgac tgttattgag tggggaaatc
    53041 tcttaggaga tgccttgcca gatgcttatt tagaattgga aattctaaaa gaagcagatg
    53101 gacgccgttt aaattttcag gcaaagggtt tgcgtgctga gaaattgtta gaggagcttc
    53161 aatatggagt atgaattgct cattagggaa gcagagccca aagatgcagc tgaattagtg
    53221 gcctttttaa atcgtgtgag tttggagaca gactttacca gcctagacgg agatggtatt
    53281 ctcttgacta gtgaggagat ggaaatattc ctcaacaagc aagctagttc ggacaatcag
    53341 ataaccttac ttgcattctt aaatggcaaa attgctggta ttgtaaatat tacagctgac
    53401 cagcgtaaga gagtccgtca tattggagat ctcttcattg tgattggaaa aagatattgg
    53461 aataatggct tgggaagttt gttgctagaa gaagcgatag agtgggcaca agcaagtggc
    53521 attctgcgtc gtctccaact gactgtccaa actcgtaatc aagcagcagt ccatctttat
    53581 caaaagcatg gctttgtcat tgaaggtagc caagagcgtg gggcatatat agaagaaggg
    53641 aaatttatcg atgtttactt gatgggtaaa ctgatagatt agtagaaata tggttaaaaa
    53701 aattattgga atggtgctag ctttactttc tgtaactgta gtaggagtag gtgtttttgc
    53761 ttatactatt tatcaacaag ggacagaaac cttagctaaa acctataaaa aaatcggcga
    53821 agaaaccaag gttattgaag cgactgaacc tctaaccatt ctgttaatgg gagtggacac
    53881 cggaaatgct gaacgaactg aaacttgggt cggtagaagt gatagcatga tcttgatgac
    53941 agtgaatcct aaaacgaaaa aaacaacaat gatgagttta gagcgggata ttctgacgcg
    54001 cattgaatca gggaatggtc aggctcatga agcgaaactg aactcagcat atgcagatgg
    54061 tggagcagag cttgctatag aaaccattca aaaaatgatg aatatccata ttgatcgcta
    54121 tgtgatggtc aatatgagag ggttgcaaaa actagtggat gcagtaggag gtattacagt
    54181 caataatatc ctaggtttcc caatttctat cagtgaccaa gaagaattta atactatttc
    54241 tatcggtgtt ggggagcaac atattggggg agaagaagcc ctagtctatg cacgaatgcg
    54301 ttaccaagat cctgaggggg attatggtcg tcaaaaacgt caacgtgaag ttattcaaaa
    54361 agtcatggaa aaagctctca gtttaaatag cgttggtcat tatcaagaga ttctaaaagc
    54421 tttgagtgac aatatgcaga ccaatattga tttgtctgca aaaagtatcc ctaacttgct
    54481 aggctataaa gattcattta aaaccattga aactcagcag ttgcagggtg aaggagagat
    54541 acttcaaggt gtttcttacc agattgtttc gagagcacat atgttggaaa tgcaaaatat
    54601 actccgacgt tctttgggac aagaagaagt tactcagctt gaaaccaatg cggttttatt
    54661 tgaagattta tttggcagag cacctgttgg tgatgaagat aattaacttt tgatacaaat
    54721 aaaaaaatca atcgtaggaa aattcctgcg attttttcaa aaaaatacga atagataggt
    54781 aggaggaaac atgaaagcag aaatcattgc tgttggaaca gagattttga caggacagat
    54841 tgtcaacacc aatgcccagt ttttgtcgga aaaactagct gagattgggg tagatgtata
    54901 ttttcagacg gctgtaggag acaatgaagt tcgtctcttg tctttgcttg agattgccag
    54961 tcaacgtagc agtctggtga ttttgacagg cggtttgggg ccaactgagg acgacctaac
    55021 caaacaaacc ctagctaaat ttttagggaa agcattagtc tttgatcctc aggctcagga
    55081 gaagttggat atcttttttg ccctgcgacc agactatgcc cgaacaccga ataacgaaag
    55141 acaagctcaa attgtagaag gagcgattcc actgccaaac gaaacaggac tggctgttgg
    55201 aggaaaatta gaagtagacg gagtgaccta tgtcgtcctt ccaggtccgc caagtgaatt
    55261 gaaacccatg gtcttaaacc aacttctacc caagttgatg acagggaaca agctgtattc
    55321 ccgagttctt cgtttctttg ggattggcga gagccagttg gttacgattt tggctgattt
    55381 aattgataat cagatcgatc ctaccttggc cccttatgcc aagacaggag aagtcactct
    55441 acgtctgtca acaaaggcta gcagtcaaga agaggcgaat caagcgctgg atatcttgga
    55501 aaatcaaatc ttggactgcc agactttcga aggaatttct ttacgagact tttgctatgg
    55561 ttatggggaa gaaactagtt tagccagcat tgtggtagaa gaactgaaaa ggcaagggaa
    55621 aaccatcgcg gctgcagaga gtttgacggc aggtcttttc caagctaccg tggcgaattt
    55681 ttctggagtt tcaagtatat ttgagggtgg ttttgtgacc tatagcttgg aggaaaaatc
    55741 aaggatgttg gatattcctg ccaagaattt ggaagaacat ggtgtggtgt ctgaatttac
    55801 agctcagaag atggctgagc aggcacgaag caagacccag tctgattttg gaattagttt
    55861 gactggagtg gcaggaccag atagcctaga aggacaccca gttgggacag tcttcatagg
    55921 cttggcgcaa gatcaaggaa ctgaggttat caaggttaat attggaggca gaagccgagc
    55981 agatgtacgt cacattgcgg ttatgcatgc ctttaaccta gttcgcaagg ctttattaag
    56041 tgactaactt ttgatataat agtagatagg tctgaggatc attagaatgt aggagaatag
    56101 aatggcgaaa aaaccaaaaa aattagaaga aatttcaaaa aaatttgggg cagaacgtga
    56161 aaaggccttg aatgacgctc ttaaattgat tgagaaagac tttggtaaag gatcaatcat
    56221 gcgtttgggt gaacgtgcgg agcaaaaggt gcaagtgatg agctcaggtt ctttagctct
    56281 tgacattgcc cttggctcag gtggttatcc taagggacgt atcatcgaaa tctatggccc
    56341 agagtcatct ggtaagacaa cggttgccct tcatgcagtt gcacaagcgc aaaaagaagg
    56401 tgggattgct gcctttatcg atgcggaaca tgcccttgat ccagcttatg ctgcggccct
    56461 tggtgtcaat attgacgaat tgctcttgtc tcaaccagac tcaggagagc aaggtcttga
    56521 gattgcggga aaattgattg actcaggtgc agttgatctt gtcgtagtcg actcagttgc
    56581 tgcccttgtt cctcgtgcgg aaattgatgg agatatcgga gatagccatg ttggtttgca
    56641 ggctcgtatg atgagccagg ccatgcgtaa acttggcgcc tctatcaata aaaccaaaac
    56701 aattgccatt tttatcaacc aattgcgtga aaaagttgga gtgatgtttg gaaatccaga
    56761 aacaacaccg ggcggacgtg ctttgaaatt ctatgcttca gtccgcttgg atgttcgtgg
    56821 taatacacaa attaagggaa ctggtgatca aaaagaaacc aatgtcggta aagaaactaa
    56881 gattaaggtt gtaaaaaata aggtagctcc accgtttaag gaagccgtag ttgaaattat
    56941 gtacggagaa ggaatttcta agactggtga gcttttgaag attgcaagcg atttggatat
    57001 tatcaaaaaa gcaggggctt ggtattctta caaagatgaa aaaattgggc aaggttctga
    57061 gaatgctaag aaatacttgg cagagcaccc agaaatcttt gatgaaattg ataagcaagt
    57121 ccgttctaaa tttggcttga ttgatggaga agaagtttca gaacaagata ctgaaaacaa
    57181 aaaagatgag ccaaagaaag aagaagcagt gaatgaagaa gttccgcttg acttaggcga
    57241 tgaacttgaa atcgaaattg aagaataagc tgttaaagca gtggagaaat ccgctacttt
    57301 ttcgattttt gattcaagtt tttagattat atatagtagc ttgaaataag atatgaacaa
    57361 ctttattagg aaagtcaaat taatttctag aaatgtttta gcagctacag cgtactattc
    57421 caaactcaac caactataat agatcgaaac tagaatagta cacatctact tctaaaacat
    57481 tgttaaaaat cgatttgact gtccttattt cattccgcta tatataagtt tgctgtttct
    57541 tgtcgctcct ctggaaagct gatataatag ctttatgaat aaaaaacgaa cagtggacct
    57601 gatacatggt ccgattcttc cctcgctctt aagcttcacc tttccaatct tgctatcaaa
    57661 tatttttcaa cagctctata acactgctga tgtcttgatt gttggacgat ttcttggtca
    57721 agaatccttg gctgcagtag gagcgacgac agcgattttt gacctgattg taggctttac
    57781 acttggtgtt ggcaatggca tggggattgt cattgctcgt tattatgggg ctcggaattt
    57841 cactaaaatc aaggaagcag tagcagccac ctggatttta ggtgctcttt tgagcattct
    57901 agttatgttg ctgggctttc ttggcttgta tcctctcttg caatacttag atactcctgc
    57961 agaaattctt cctcaatctt atcaatatat ttctatgatt gtgacctgtg taggtgtcag
    58021 ctttgcttat aatctttttg caggcttgtt gcggtctatt ggtgacagtc tagcagccct
    58081 gggatttctg attttctctg ccttggttaa tgtggttctg gatctctatt ttattacgca
    58141 attgcatctg ggagttcaat ccgcaggact tgctaccatt atttcgcaag gtttatcagc
    58201 ggttctctgc ttttattata ttcgtaaaag tgtgccagaa ctcttgccac agtttaaaca
    58261 tttcaaatgg gacaaaagct tgtacgcgga tctcttggag caaggtttgg ctatgggctt
    58321 gatgagttca attgtatcta tcggcagtgt gattttacag ttttctgtta atacatttgg
    58381 tgcagtgatt attagtgccc agacggcagc tcgacgcatt atgacctttg cccttcttcc
    58441 tatgaccgct atttctgcat caatgacgac ctttgcttct cagaatctag gagctaagcg
    58501 acctgaccgt attgttcaag gtcttcgaat cggcagtcgt ttaagtatat cctgggcagt
    58561 ttttgtttgt attttcctct tttttgccag tccagctttg gtttccttct tggctagttc
    58621 gacagatggt tacttgatag aaaatggaag tctctatctg caaatcagtt caacctttta
    58681 tcccattttg agcctcttgt tgatttatcg caattgcttg cagggcttgg ggcaaaagat
    58741 ccttcctcta gtttctagct ttattgaact aatcggaaaa atcgtttttg tggttttgat
    58801 tattccttgg gcaggatata agggtgttat cctttgtgaa cctcttatct gggttgccat
    58861 gacagttcaa ctgtacttct cattattccg tcatcccttg ataaaagaag gcaaggcaat
    58921 cttggcaacc aaagtgcaat cctagttgga tttactgaat aaaatccatt tcctctagtg
    58981 aaaatcgaaa aaacttgtgt tctcgtcttt agtttggtgt tgaaaatagt ttaacagact
    59041 tttgacttct tttatatgat ataataaagt atagtattta tgaaaaggac atatagagac
    59101 tgtaaaaata tacttttgaa aagcttttta gtctggggtg ttattgtaga tagaatgcag
    59161 accttgtcag tcctatttac agtgtcaaaa tagtgcgttt tgaagttcta tctacaagcc
    59221 taatcgtgac taagattgtc ttctttgtaa ggtagaaata aaggagtttc tggttctgga
    59281 ttgtaaaaaa tgagttgttt taattgataa ggagtagaat atggaaatta atgtgagtaa
    59341 attaagaaca gatttgcctc aagtcggcgt gcaaccatat aggcaagtac acgcacactc
    59401 aactgggaat ccgcattcaa ccgtacagaa tgaagcggat tatcactggc ggaaagaccc
    59461 agaattaggt tttttctcgc acattgttgg gaacggttgc atcatgcagg taggacctgt
    59521 tgataatggt gcctgggacg ttgggggcgg ttggaatgct gagacctatg cagcggttga
    59581 actgattgaa agccattcaa ctaaagaaga gttcatgacg gactaccgcc tttatatcga
    59641 actcttacgc aatctagcag atgaagcagg tttgccgaaa acgcttgata cagggagttt
    59701 agctggaatt aaaacgcacg agtattgcac gaataaccaa ccaaacaacc actcagacca
    59761 tgtggatcca tacccttact tggcaaaatg gggcattagc cgtgagcagt ttaagtatga
    59821 tattgagaac ggcttgacga ttgaaacagg ctggcagaag aatgacactg gctactggta
    59881 cgtacattca gacggctctt atccaaaaga caagtttgag aaaatcaatg gcacttggta
    59941 ctactttgac agttcaggct atatgcttgc agaccgctgg aggaagcaca cagacggcaa
    60001 ctggtactgg ttcgacaact caggcgaaat ggctacaggc tggaagaaaa tcgctgataa
    60061 gtggtactat ttcaacgaag aaggtgccat gaagacaggc tgggtcaagt acaaggacac
    60121 ttggtactac ttagacgcta aagaaggcgc catggtatca aatgccttta tccagtcagc
    60181 ggacggaaca ggctggtact acctcaaacc agacggaaca ctggcagaca agccagaatt
    60241 cacagtagag ccagatggct tgattacagt aaaataataa tggaatgtct ttcaaatcag
    60301 aacagcgcat attattaggt cttgaaaaag cttaatagta tgcgtttttt tgtggagata
    60361 tttccttcaa tgtttgctac tatattaaac aaaaatcaga aagcaaacta gaaagttatg
    60421 ctcaaataaa atctaaattt gacaatgtaa accgagtcgg atagctttaa gtactgtttt
    60481 gaggttgaag atacgatttt tgataggaac tcatcaattt tagattttta agcagcatca
    60541 ataaattgct tccttgtttt gtcataattt ttttatttaa aaaattatga caagagtgtg
    60601 ctattctttt tatgagaggt gtatgaatat gataaatgta tgtgataaat gtatgtgatg
    60661 ttggaaaaag aataaaagaa cttagaatat cttcaaatct tactcaagat aagattgctg
    60721 agtatttgtc tttgaatcaa agcatgattg ccaaaatgga aaaaggtgaa aggaatatca
    60781 cgaatggatt taagtaataa agctccaaat cttagaaaaa agttgggagc tgatggtgaa
    60841 tcgccgatag atatttttaa attggtacaa aagatagaaa atttgacgct ggtattttat
    60901 ggactcggaa agaatattag cggagtctgt tataaaggaa ctcagttcag tctcattgca
    60961 gtcaattcag acatgtcatt aggaaggtaa agattttctt tagcacatga actgtatcat
    61021 ctttattatg atgaggtgaa gaagagttca gtcagtctta tcttgattgg tgaaggagat
    61081 gaaactgaaa gaaaagcgga tcagtttgct tcttattttt taattttccc atcttcactg
    61141 tataggatgg ttgaggaaat tagagaaaat gccaatagaa ctcatcttga agtagaagat
    61201 attataaaat tgggtcagtt ttatggtatc agtcataaag ctatgttata tagattgaga
    61261 aatgatggat accttgatgc agaagaaatt aaaaatatgg atattagtgt tatagagaca
    61321 gcttcaagat taggctatga tacaagttta tatcgtcctt tgtcagaaag taaaaaggaa
    61381 atggtattag gacactatat taaatcgact gaacaacttt tagaaaataa tagaatttcg
    61441 caagggaagt atgaggaact gttactagat gctttcagat atgatattgt atatgggcta
    61501 gatgaagagg gggagttgtc gtttgactag tcgtgtattt attgatgcag attgtatttc
    61561 agcattttta tgggttggca ctgaacatct tttagaaaag ctctattcgg gtaaaattgt
    61621 tattccacaa gaggtgtatg atgaaatcaa tatacctaca attccccatt taaaatctag
    61681 gatagaccag ttggtaacta agggttcagc tgagattgtg agcatagaca ttggaactga
    61741 agaatacgca ttatatagag atttaacaag aaatcatgat agtaacaaga ttattggtaa
    61801 gggagaagcg gcttctattt ccttagcgaa aaagcataat gggatattag gaagtaataa
    61861 cctaagagat gttaaatcat atgtagaaga attttcttta gaacatatga caacaggaga
    61921 tatactgatt gaagcgttta aagcgtaatt tattactgaa caagagggca atcatatctg
    61981 gaataatatg cttaaaaaga gaaggaaaat tggtgcaaat tcattttcag actatcttcg
    62041 tggaagtatt catcaaaata gacaaaaata aatttggata aatcgaactc actattcagg
    62101 aggcatatga gcaattcgaa aaagaaaagt gtcaaattga gcctatagga gtagaagtga
    62161 aatagtaagt cctgcatagt ggatgagaga aaagttctcc ttgaagtttt cctgaactat
    62221 cagtcgcatg tcaaacgata tgtagggtaa tgtgagaggg gatagcgagt agtttttggt
    62281 tattttatca aaaaacttat attttattat accgaatgat aaaatataat aaaaatgata
    62341 gaataaggaa aaaacatgaa tgtcaaaaag ataatgtcaa tttttcaatc cttttatgtt
    62401 gatgtcagta ttgaggaact gactttgact ttaccaatca gttttgtaaa aaggtttgag
    62461 tatactcaaa tgacttttca taaggaatca tttttattga ttaaagaaaa gagaaggggg
    62521 agtttgagtt catttgttac tcaggctcgc actatgggtg aaaaagccaa tatggatgtt
    62581 gttttggtgt tttcgaagtt atcagacggt gaaaaaaagc aattacttca agctagagtt
    62641 ccgtttgtag actttaaggg aaacctcttc ttccctccat tgggactagt actgaatgcg
    62701 aatgatactg aagtccctaa ggaattaaca cctagcgaac aattaacgtg gattgccttt
    62761 ttattgccag atggcgatat aaagcagata aaatctgttt ctaaccttct atatggtggt
    62821 gcttatgctt tgtcgcattc aactttttta gctgaaacgg atgaaaatac tagctatgtc
    62881 atatggcaga gaaaattcaa tcagttatcc ttgccacttt ctcagcatgt tttaaaatga
    62941 aagatgctag agatatggaa atatcgtcct tttgtatctg agttttggaa tgattttaaa
    63001 aataatcatg ataaacaatt tgtagatccg atttctcttt atttgacctt aaaagatgat
    63061 gatgacccac gtatagagga agagagtgaa gcactagaaa atatgatatt acagtatttg
    63121 ggagaagatg atgccagcta atacgaaagt tatttttcaa gaaatgtttg cggattttca
    63181 gaactattat gttctgattg ggggaactgc tacctctatc gtattggatt cgcaaggatt
    63241 taaaagtcgc acaacaaaag attatgatat ggtcatcatt gatgaagtaa aaaataagga
    63301 attttatact accttgaatc attttttaga attgggagag tatcaaggaa gtcagaaaga
    63361 tgagaaagcg tagctttttc gatttacaac aactaatcct gagtttcctt ctatgattga
    63421 actatttagt atcttaccag aatatccatt aaagaaggac ggtcgagaaa tttccttata
    63481 ttttgaccaa gatgctagtt tatcagcctt attattggat gaagattatt ataatatatt
    63541 ggtgcatgta aaagaaacca ttcaggggta ttcggtattg agtaattgtg gtctatactc
    63601 ttcgacaatc tcttcaaacc acgtcagctt ccatctacaa cctcaaaaca gtgttttgag
    63661 cagcctgcag ctagcttcct agtttgctct ttgattttca ttgagtatta attattttta
    63721 aggctaaagc ttggctggat atgagagagc gctctgctac aggtgctcaa ggtttaagta
    63781 agtccattaa aaagcatttg aatgacctta cccgtttgac agcttccttg ctaggagatg
    63841 aaaagttatc ggctataaca tcaagtagtg cggtaaaagc agacatgcac cgctttgtga
    63901 tagaattaga gcttgtgaag tcaactattc ttcaaaatga tgacatttca ttagatcaaa
    63961 atgaaatttt tgaaattctg aaaaattttt tcgatggtta aaataattgt agcgagatgg
    64021 ctatattgaa ttcgtctata tctggaaact agaaaaaact tcaatttcag gagaaaatga
    64081 agtcaatctt cccacaatca aacgtatagt atcaaggttt ttcaagacct gatattatgc
    64141 gttttttgct tttcaaaact ttttgcccag tctttgtttt tatcctctag tcacttgatt
    64201 tgtttcaggt ggttttttag tatagtaaaa tgaaacgaga acaggacaaa ttgatcagga
    64261 cagtcaaatc gatttctaac aatgttttag aagcagaagt gtactattct agtttcaatc
    64321 tactatagtt aaatctgcgg tcaagtctac tggtgaatct atgattgtaa tactcttcaa
    64381 aaatctcatc aaccacgtca gtctcgcctt gcagtctgta tcttactgac caagctagtg
    64441 atggacttag aataggtgat tttgagcgtc ctattggcta ggaaatgctg atcatagtcc
    64501 tttgctgagg ctagggtgtt tcaacactca actggttgat ctagttgata ggaagggaat
    64561 tactataaaa tactcaggct tccatcatat tttttgaaac gattgtgtaa tcaaaatgta
    64621 ccaatattgt agtattggta cagaagatgt tgtgaatgga taaatatatc ataactgctg
    64681 tctctctatg taaaaagaag gctgtatcaa aaagatttca tatgtctgtg catatataat
    64741 agacttcctg cgaaaccaaa atcctagttc atgattgata ataccagcaa tcaaattcat
    64801 tcgtaatccg aagcgtttac gatgatttcg ataggttgtt gaaatcattt taaacgtttt
    64861 tactttggca aagatgttct caaccttgct tctctccttg gatagcgcat ggttacaggc
    64921 tttatcttca actgttagtg gcttgagttt gctggattta cgtggagttt gtgcttgagg
    64981 atatatcttc atgagccctt gataaccact gtcagccaag attttaccag cttgtccgac
    65041 ttttttgata agctgttttt aatacagcta acatctcttt aaaagtggta cgctgaacac
    65101 taacaagacg cttaaatcgt gcatcagtta gttgtttact tgcttcataa ttcatagaac
    65161 tactatacca tattttgttt cgcaggaagt ctaataagtt atagtccagt ttttactata
    65221 ctttgatatt caaatatgtt atactatggt tatcaaagta aatgaaagga gttacgaata
    65281 tgacgccaga agaaatgtac ctgacagagc gattagacgt acagatagct cattttttaa
    65341 agaaaagcgt tcaacatcgt aggcgctata aggtattaaa aataacagaa atcgtggcag
    65401 gtttcctcat agctgtcttt tgtgctattc ctatgccagg tgatcgctac cgtttgattt
    65461 cggttgcctt atccagtctc ggcttgctgt gtgaggggat tatcaatttg tataatgcaa
    65521 aggaaaattg gatttcttac caaaaaactg cgcaactcct ggagaaagaa aaattcctct
    65581 atcaatgcca aacggagaaa tatgcaggaa agaccaaggc ttttgcccta tttgtcaaga
    65641 catgcgaagg tcttatctca gaggagatta accagtggga aagtatccag tcaaaagaag
    65701 tggcagctag tgcagatgct ccagttaaaa aagagtagga ggtagaggaa atgtctcaat
    65761 ccagttacct gtcgcccttg ctctggttaa aaaaagaagc cgataaggaa aagatgagcg
    65821 cgacccagtg ccagatattt ttcttttact atcaaatgtt tgagctctta tttgctagag
    65881 aaagcgacat gaaagactta tgtctgggaa cgaaaggttt ttatttctcg cagttagaga
    65941 aaaatttgct ttctggagtt tcccgatttc taaaaaactt ggaggggaaa gtaactctca
    66001 aggctaacca agaagtatca gctcgcaaag ccctttttct agccttgaca actagccaat
    66061 cagattggca ggagttagct cctgtttttg atttttatca gactatcggg aggcttgaaa
    66121 atccttctct cttgagttct caggacagac aacatctgat gtggatttac cagtcagctt
    66181 tggagaagga ttatattgtc aaggttattg gcgacaagca ttttgtattg aagagacaag
    66241 atgctactaa attgacagcg cgccaaactc aaactttgga aattctgagt caatcagaag
    66301 acttggtcaa tcctgtctat gttacattag gagaaaaggg ggtgctcttg cttgattaag
    66361 agaggagatg ttgtagctct ttatttgcct tttccgacta ttagtagcga tttggctgtg
    66421 aagaatcata tgtatatctg tattgacaac agcatgacta aaaacaaaga gttggttaaa
    66481 aatcagacct tcaaaccagc tctcttgacc agacgtttgg tcaagaactt tatgatagaa
    66541 gagccggatc tagctcgtaa tccttttaca agaccaacct tgattgactt agataaggta
    66601 tttatgttgg ataatacggt tattccgact tcttatctag ccagacggcg acgcaatgtc
    66661 tcagaagaat tgtacgagga aattttggat cacttagtcc aaccacggct gatttcgctg
    66721 aacaagtctg agtttatgca actcaatcca ggaacttatt aggaggtaga agatggcaaa
    66781 taaagcagta aatgacttta tactagctat gaattacgat aaaaagaaac tcttgaccca
    66841 tcagggagaa agtattgaaa atcgtttcat caaagagggt aatcagctac ccgatgagtt
    66901 tgttgttatc gaaagaaaga agcggagctt gtcgacaaat acaagtgata tttctgtaac
    66961 agctaccaac gacagtcgcc tctatcctgg agcacttctc gtagtggatg agaccttgtt
    67021 agagaataat cccactcttc ttgcggttga tcgtgctccg atgacttata gtattgattt
    67081 gcctggtttg gcaagtagcg atagctttct ccaagtggaa gaccccagca attcaagtgt
    67141 tcgcggagcg gtaaacgatt tgttggctaa gtggcatcaa gattatggtc aggtcaataa
    67201 tgtcccagct agaatgcagt atgaaaaaat cacggctcac agcatggaac aactcaaggt
    67261 caagtttggt tctgactttg aaaagacagg gaattctctt gatattgatt ttaactctgt
    67321 ccattcaggt gaaaagcaga ttcagattgt taattttaag cagatttatt atacagtcag
    67381 cgtagacgct gttaaaaatc caggagatgt gtttcaagat actgtaacgg tagaggattt
    67441 aaaacagaga ggaatttctg cagagcgtcc tttggtctat atttcgagtg ttgcttatgg
    67501 gcgccaagtc tatctcaagt tggaaaccac gagtaagagt gatgaagtag aggctgcttt
    67561 tgaagctttg ataaaaggag tcaaggtagc tcctcagaca gagtggaagc agattttgga
    67621 caatacagaa gtgaaggcgg ttattttagg gggcgaccca agttcgggtg cccgagttgt
    67681 aacaggcaag gtggatatgg tagaggactt gattcaagaa ggcagtcgct ttacagcaga
    67741 tcatccaggc ttgccgattt cctatacaac ttctttttta cgtgacaatg tagttgcgac
    67801 ctttcaaaac agtacagact atgttgagac taaggttaca gcttacagaa acggagattt
    67861 actgctggat catagtggtg cctatgttgc ccaatattat attacttggg atgaattatc
    67921 ctatgatcat caaggtaagg aagtcttgac tcctaaggct tgggacagaa atgggcagga
    67981 tttgacggct cactttacca ctagtattcc tttaaaaggg aatgttcgta atctctctgt
    68041 caaaattaga gagtgtaccg ggcttgcctg ggaatggtgg cgtacggttt atgaaaaaac
    68101 cgatttgcca ctagtgcgta agcggacgat ttctatttgg ggaacaactc tctatcctca
    68161 ggtagaggat aaggtagaaa atgactagga gaggagaatg cttgcgacaa aaagaggcga
    68221 tgatctctct gcggatatct gaaagtttat ctcttgccta gcgatttcca ttggagtatg
    68281 ctcgtgatgt taaaatgagt ctatcaaaca ggatgtgtaa aaaagtaaaa agggtagcca
    68341 attccttgat atacagggga ttgattatcc tttacttgtt ttagatgatt ggaaattcaa
    68401 gaatgacacg tatcggaaat attttgctgt ttatatctaa tacccattta tggaaaaaat
    68461 gaaattaaat atgaacaaat caattgctag caatggttta gaagtgccag tgtactagtc
    68521 taacttctcc atcttgggaa cacgtaaatt atactcttcg aaaatctctt caaaccaggt
    68581 cagccctatc cgcaacctca aaacagtgtt ttgagcaacc tgcggctagc tttctgattt
    68641 gttctttgat ttttattgag tattagaggt ttgcttagaa actcttctat tgatttctta
    68701 gaatacaata gcgcctataa gaactgttgg atttcaaagt atttacttga actatgatat
    68761 gtctggagta gactgtcaac aaaaggtgca gtatgattgt ttttgtcgct tatatctaca
    68821 aacttcaaac agtaatttga gctgactttg tcaaacttgg ctgaaacttt ctatttgcag
    68881 ataatggtct agtttgtttt ttgaatgtgg atgagtgtct gttgataaag atagaaaggc
    68941 aagaccatct tagcaggtaa agtgctatcc tagcttgatt tgctaataaa atccatttcc
    69001 tctagtgaaa atcaaaaaaa cttgtgttat aataagaaag attaaaatgt gaaaaaagga
    69061 gattcctaat gggacgtaaa tgggccaata tcgtagccaa gaaaacggct aaagatggag
    69121 ctaactctaa agtatatgca aaatttggtg tagaaatcta tgtagcagct aaaaaaggtg
    69181 atccagatcc agaatcaaac tcagctttga aattcgttat cgaccgtgct aaacaagccc
    69241 aagtgccaaa acacattatc gataaagcga ttgataaagc caaaggaaac acagacgaaa
    69301 cctttacaga aggacgttac gaaggttttg ggccaaatgg ctctatgcta attgtggata
    69361 ctttgacttc taacgttaac cgtacagcag ccaatgtccg tgcagccttt ggtaaaaacg
    69421 gcggaaacat gggcgcttca ggttctgttt cttacctttt tgacaacaaa ggtgttattg
    69481 tatttggagg tgaagatgcg gacgcagtct ttgagcaatt gctcgaagcg gatgtggatg
    69541 tggatgacgt agaagcacaa gaaggtacaa tcacagttta cacagcgcca actgaccttc
    69601 acaaggctat cgttgctctc cgtgagtctg gtattgaaga attccaagtg actgaattgg
    69661 aaatgattcc tcagtcagaa gtggaattgt caggcgaaga ccttgaaacc tttgaaaaac
    69721 tttacagcgt tcttgaagac gacgaagacg tccaaaagat ttatacgaac gtagatgggt
    69781 tttaatttaa cctatagaac atgatcctaa gtgagaaaat cacttgggat ttttttaatc
    69841 aagaaaatag ttctcataga aatttaatta ttctccagag aactattttt atttagaagg
    69901 gggagattat ggataaaccg atgttagtct ttaagcgttt tggtcatcaa attcacctga
    69961 tggtgcaaaa ggaagccaaa cgttgcggca ttgaatttat gggtgggccg caaggtcagg
    70021 ttgtgcattt tttggataat cgcgagaaaa accaagactt ggtcttgatt aaagatatcg
    70081 agcaggaact caatattacc aagtctgttg ctagtaatct ggttaagcgt atagtgcaaa
    70141 atggtttggt ggaattggag gcgagtcctg ttgataagcg ggctaagttt gttcgtctga
    70201 cggacaaagc acgttctcag atgcaacagg ttaaggcttt ttttgaacgc atagacaagc
    70261 agttgatgga agacattgat gaagatgaat tactgatttt tgagaaagtt ctcggtcaac
    70321 tacaggcaaa tatcaaggga ataggaggag agaataaaga aattagccaa aagaattagt
    70381 agaaaagaat ggggatgatt ttactagcca ttctctttac ttgcttttcg gtctatctag
    70441 agttggaagt gccgacctat atctcgaaaa ttacggattt gctaggtagt caaggaacta
    70501 atttagatga gttgtggcag ccggcaagca tgatgatggg aatgctcttt cttgccttct
    70561 tgtccgtagt tgcagttgga ttttttgcat cccgagtggc ggcttcttat actagtaggc
    70621 tgagaagtga tatttttaac cgagttttgg attactcgca gacagagatt aagaaatttt
    70681 caattcctag cctcttgacg cgtactacca atgacattac tcaagttcaa atgttgatta
    70741 ctatgggctt gcaagtggta acgcgtggtc caattatggc tatctgggct attgggaaga
    70801 ttttaggtca ttcagaatac tggctctggg ccgtacttgt ggcagtgatt gtcaacgtcc
    70861 tgatgacgac cgttttgatg acgctagcct ttccaaaaca gtccttgatt caggggttga
    70921 cagataaact gaacagtatc actcgtgaga gtttaacagg tattcgtgtc gttcgtgcct
    70981 acaatgcaga ggattatcaa aatgaaaaat ttgcagcagt aaatgatgaa ttgacccgtt
    71041 tgaatttgtt tgtcaaccgt cttatggcta ttttgaatcc tatcatgatg gggatttcaa
    71101 gtggtttgag tgtagcgatt tactggattg gggcctatgt gattaacgac gctgctccga
    71161 tagcgcgtct gcctctcttt agtgacatga ttattttcat gtcttatgcc atgtaggttg
    71221 tcatgggctt ccttctcatg ggagcactct tcatcgttct tccccgaact atggtctctg
    71281 ctaagcggat taatcaagtt ttagatttgc attcttctat ccaaaaccct gttcaagtgc
    71341 agctgactga tgaaaacttc aaaggtcagg tcgagtttaa ggatgtgacc ttccgctatg
    71401 cggcaaattc ggaggcagtt attgaacatg ttagctttaa agcagaaact ggtcaaacag
    71461 tggcctttat tgggtcaaca ggttctggta aatcaactct ggtcaatctg attccacgtt
    71521 tctacgacgt gtcagcagga gaaattctgg tggacggtgt caatgttcaa gactatgact
    71581 tctctgtgac agctcatgct ggtcaaaggg ttgccattgt tgggccgact ggggctggta
    71641 agacaaccat tgtcaatctt ttgatgaaat tctatgagat tgataaggga agtattcgca
    71701 ttgatggtgt ggataccaag gctatgacgc gttcagaagt gcatgatgcc ttttcaatgg
    71761 tcttgcagga tacctggctc tttgaaggaa ctattcgaga caatctcatc tataatcaaa
    71821 tagggattag tgatgaacga atgatggaag ctagtaaggc tgtgggaatt caccacttta
    71881 ttatgacctt gccagatggc tatgatacca tcttggatga cactgtgacc ttgtctgtag
    71941 gacaaaaaca actattgact attgcttgtg cccttcttaa ggatgcatcg cttttgattt
    72001 tggatgaggc gacttcttct gttgacacac ggacagagga attgatccaa aaagccatgg
    72061 accgtttgat ggaaggacgc acatcctttg tcattgccca ccgcttgtca accatccgaa
    72121 atgcagactt gatcttggtc atgaaagatg gaaatatcat cgagcaaggc aactatgagg
    72181 aactgatggc gcaaggtggc ttctacgctg acttgtacaa tagtcaattt acagaagatg
    72241 aagcagaaga ataaatcaaa aaaggcttga cggccttctt tttcttattt atactagtac
    72301 acatagaaag agagaagtat gagtcagaaa ttatacaata tgaaatttgc tgctgtctac
    72361 ttagccttga ttgcaaaagt tgagcgaaag ggtgaaaagg cagagtcagt tcaccaagtg
    72421 accagttggt tgacagggta tgaagtgagt gacgttcttg cttgtctgga tagggatgtt
    72481 acttacggag atttttttct acaagcacca tattatgtcc ctgaacgaat tacaattaca
    72541 gggaagattt gcggtgtccg tattgaggaa attgatgatc ctctgatgca ggaaatacgt
    72601 cgcttggaca agctagtgga ttggcttgcc aaggggaaaa catctcaaca agttctagaa
    72661 aagtatgaga agcataaatg aaaaattatc aagaatggta tcgaaatatc agctccagac
    72721 taactagtcg tccaattctt ttattcctat tacgcagttt caatcgtttg atgacagtcg
    72781 ccatgcccct ggtctatctg atcttgctag tcaccactta cctgcaacta ggacttggtc
    72841 agcaagttgg ggtttatgtg cttattcctg catcaggttt tgtggccttg tccctgtttc
    72901 gtaagaaaat caatcacccg agaccttatg aaacttggga tatctgtccc cttcttgata
    72961 aggatagtgc gggacggtcg atgcccagtc gccatgtctt ttcagctttg ctggggttgg
    73021 tgagggtttt agggggtgtt cattatccca aggatgtctt ggttggctat gcttgtggtc
    73081 tggtgtgggg attccttttc ttcctattct gacatgtaag ttaagctagt cctacaacca
    73141 cttactgctt caaattgacc acttgctttt ttgcccttgt attcctaact tagctttgat
    73201 atagtagagt cagaaaggag atgtgatgaa gttacgaatt gagattgacg gcaatttaga
    73261 ggagactgaa attgtcatca agacccccac tttgacagat gaaattgcag acttgcaacg
    73321 gctcttgcaa gagtcaaagg ctccgaggtt gactttttac aaggggacag gtgaatatta
    73381 tctagacctg tcagaaattc tcttctttga aacagaaggg agcaagatct acgctcataa
    73441 ccagaaggaa gcttatgagg ttcgcctcaa gctctatgag ttggagtcta tcttgcctcg
    73501 ctattttaat cgagtttcca agtcaacgat cgcaaacatc cgtcagattt actcagtgga
    73561 caagtccttt tcaggaacgg gcaccatttc cttttatcag acgcacaagg aggttcatgt
    73621 ctcacggcat taccaatccc tcctaaaaga aaatctaaga aacatgaggt aataagatga
    73681 aaaagaaagc atttggtatt gtgttacttg tactagcagc tttaatatta gtacaaggaa
    73741 attttggaat cccttctcta ggagggcaca tttggccctt gattggtatt gctttttttg
    73801 cctaccaatc agttggagct ttgttgcgtc gccacttaac ttcagcctct tttacagctc
    73861 tagtagcctt aatgattgct aaccactttt atggcatttt accgattcca aaccagacac
    73921 taatctgggc aggagttcta atcgttctcg gagtaaatat gttgactcat tctaacagaa
    73981 cttggaatgg gaaaaaatgg tggtatgatg gtgaaaaaaa cattcttata gataaggaag
    74041 ttgcttttgg gacagggact ttctacaagc aagaccaaga attggtagaa gaccaagtag
    74101 aagttggttt tggcaatgca aaaatctact atgacaatgc agagatgtta ggtgattttg
    74161 caactttaaa tattgaagta gcttttggta atgcaactgt ctatgttccg caacactggc
    74221 gtgtcgattt gaaagtagaa acatcctttg gtacagccaa ggcggacgct cctgtagcgc
    74281 caacaagcaa aaccttgatt attcgtggag acgtggcctt tgggaagttg gagcttgtct
    74341 acgttaaata aaaaaatctt cacttaaacc atcaaaatag acgtactaag agtaggaaat
    74401 tgatgccttg ctctgatttc agttctatgg ttgttagact ttaaaaaatg aaatgttgcc
    74461 tttaaaagtt gtatattttt cgatattttg actcttacgt ttgatgtatc tatgtcctac
    74521 agcgtggatg atgtagtgta aaatgcttta aaaaaaaaat gaatgatatt ggacagtttt
    74581 tttgaacttt taattgctca ggagccatga aagcaagcgc ttgggtttat gacaagggag
    74641 aatggtatta tgtaagttct tctggttcca tgattgcgaa tgattgggtc aaagacaatg
    74701 gcaagtagta ttatctggct tcatcaggta agatgcttcg caatacctac acacctgata
    74761 gttactacgt tggcaactta ggtgcctggc aataagaata atactcttcg aaaatctctt
    74821 caaaccacgt cagcttcatc cacaacctca aaacagtgtt ttgagctgac ttcgtcagtt
    74881 ctatctacaa cctcaaagca gtgctttgag cagcctgcgg ctagcttcct agtttggtct
    74941 ttgattttca ttgagtataa gaagtccttt tccttaaagg aagaggcttt ttacttgctt
    75001 ttttgctgtt tcctcatttg tcctaaagcc ttttttgtgt taaaatgaat ggtatgaaag
    75061 ctaaaaaaat gtggatggca ggtctggctc tgcttggtat tgggagcctt gcccttgcta
    75121 cgaaaaaagt tgcagatgac cataagctca tgaagactca ggaagagttg acagcgattg
    75181 tacgagacca tttttcagac atgggggaaa ttgcgaccct ctatgttcaa gtctatgaaa
    75241 gcagtctaga gagcttgctt ggtggcgtta tttttgagga tggccgtcat tatacctttg
    75301 tctatgaaaa tgaagaccta gtctatgagg aggaagtctt atgatacaac cagcaagttt
    75361 agaagaattg gcatctttag tagaaaaaga cggtaagaag gtcttccttt ttgtggcgga
    75421 ctggtgtggc gattgccgtt atatctatcc tgccttacca gaaattgagg agagtaatcc
    75481 agagtttacc tttattcgag tggatagaga ccagtatata gatttggcca aactctggga
    75541 tgtatatgga atccctagcc ttgttgttct agaaaaggac aaggaaatcg gtcgttttgt
    75601 caatcgcgac cgtaaaagca agcaacaaat taacgatttt ttagcaggat tgaaatagga
    75661 gaaaaaggaa acaatgattt ttacatataa caaagaacat gtcggtgatg tccttatggt
    75721 catcgtgaaa aatagcggag atgctaaact gaatgtggaa cgcaaagaca aggtagcccg
    75781 tgttttcctc aaagaaaatg gggaaacagt agcttggaac atttttgagg tttcgagctt
    75841 gtttgaaatt gcagagcgcg gtcaagtctt tttatcagat gagcaagtcg ctcgtttgaa
    75901 ccaagaatta caggcggaag gttttacaga agaaattgtt aatgataagg aacctaagtt
    75961 tgttgttggt gaaattgtcg agatggtagc tcatccagac agtgaccacc tcaacatctg
    76021 ccaagttgca gtcgcaagtg acaagatagt gcaaatcgtt gcaggagcac ctaatgcgcg
    76081 tgttgggttg aaaaccattg tggctcttcc tggtgccatg atgccaaaag ggaatttcat
    76141 tttcccaggc gaacttcgtg gtgaaaagag ttttgggatg atgtgtagtc ctcgtgaatt
    76201 gcatttgcca aatgctccgc aaaaacgtgg ggtgcttgaa ttatcagaag accaagttgt
    76261 cggaacaccg ttcgacccag cgaaacactg gactgcctag gaacttgtca gcatctgata
    76321 gaaggaaata agatggcaaa aaatgtagtg attacgggag caacctcagg aatcggtgaa
    76381 gcgattgcgc gtgcttatct ggagcagggt gaggatgtcg ttctaacagg acgacggata
    76441 gacagattag aaatcctcaa gtcggagttt gcagtaagct ttccaaatca aaccgtctgg
    76501 acttttccac tagatgtgac ggatatggtc atggtgaaga ctgtttgctc tgatattcta
    76561 gaaacgatag ggaggattga tatcttggtc aacaacgccg gactggctct tgacttggct
    76621 ccctatcaag actatgagga gttggatatg ttgaccatgt tggataccaa tgttaaaggt
    76681 ctgatggcgg ttactcgctg tttcttgcca gcaatgataa aagtcaatca aggtcatatt
    76741 atcaatatgg ggtcaaccgc aggaatctac gcctatgctg gtgccgctgt ttactcagct
    76801 accaaggcag cggttaagac cttttcggat ggactgcgaa ttgataccat cgcaacggat
    76861 atcaaggtga caaccattca gcctgggatt gtcgaaacag atttctcaac tgttcgtttt
    76921 catggtgata aagagcgggc tgcgtccgtt taccaaggaa tagaagcctt gcaagctcag
    76981 gatattgcag acacagtagt ctatgtgacc agtcagcctc gccgtgttca gattacagat
    77041 atgaccatta tggccaatca acaggcgaca ggtttcatga ttcataaaaa ataagaaatt
    77101 tcctcgaaaa gttacaaatt tctgtaactt tttttgattt cctacgaata gataagtagg
    77161 aggaagaaaa tatgtataat aaagttatca tgattgggcg tttaacgtct acaccagaat
    77221 tgcacaaaac caacaatgac aagtcggtag cgcgagcaac tatcgctgtg aaccgtcgtt
    77281 acaaagacca aaacggtgaa cgtgaagctg attttgtcaa tatggtccta tggggcagac
    77341 tagcagaaac tttggcaagc tacgcaacca aaggtagtct catttccgtt gatggagaat
    77401 tgcgtacccg tcgctttgag aaaaatggcc aaatgaacta cgtgaccgaa gtacttgtca
    77461 caggattcca actcttggaa agtcgtgctc aacgtgctat gcgtgaaaat aatgcaggcc
    77521 aagatttggc agatttggtc ttggaagagg aagaattgcc attttaatac tcttcgaaaa
    77581 tctcttcaaa ccacgttagc tttatccaca acctcaaagc agtgctttga gcagcctgcg
    77641 gctagcttcc tagtttgctc tttgattttc attgagtata aacattaaaa agtctgagtt
    77701 ggtctcaggc tttttatctt gagaaagtca gacttttttc ttgactattt ctgaccaagt
    77761 gatacaatag aattatgaat tagcactcaa gttcaaagag tgctaataat atctatctca
    77821 ttatggagga aatcagatgt tgaaaccatt aggggaccgt gtggtcttaa aaatagaaga
    77881 aaaagaacaa accgttgggg gctttgtcct tgcaggctca gcccaagaaa aaaccaaaac
    77941 agctcaagtt gtggctactg gacaaggtgt tcgtaccttg aacggtgact tggttgctcc
    78001 aagtgttaaa actggagatc gtgtcttagt tgaagcccac gcaggtcttg atgtcaaaga
    78061 tggcgatgaa aagtacatca tcgtaggcga agctaacatt ttggcaatca ttgaggaata
    78121 gaaggagaaa gtaagtatgt caaaagaaat taaattttca tcagatgccc gttcagccat
    78181 ggttcgtggt gtcgatattc ttgcagacac tgttaaagta accttgggac caaaaggtcg
    78241 caatgtcgtt cttgaaaagt cattcggttc acccttgatt accaatgacg gtgtgaccat
    78301 tgccaaagaa atcgaattgg aagaccattt tgaaaatatg ggtgctaagt tagtatcaga
    78361 agtagcttct aaaaccaatg atatcgcagg tgacgggact acgactgcaa cagtcttgac
    78421 ccaagctatc gtccgtgaag gaatcaaaaa cgtcacagca ggtgcaaatc caatcggtat
    78481 tcgtcgtggg attgaaacag cagttgccgc agcagttgaa gctttgaaaa acaacgccat
    78541 ccctgttgcc aataaagaag ctatcgctca agttgcagcc gtatcttctc gttctgaaaa
    78601 agttggtgag tacatctctg aagcaatgga aaaagttggc aaagacggtg tcatcaccat
    78661 cgaagagtca cgtggtatgg aaacagagct tgaagtcgta gaaggaatgc agtttgaccg
    78721 tggttacctt tcacagtaca tggtgactga tagcgaaaaa atggtggctg accttgaaaa
    78781 tccgtacatt ttgattacag acaagaaaat ttccaatatc caagaaatct tgccactttt
    78841 ggaaagcatt ctccaaagca atcgtccact cttgattatt gcggatgatg tggatggcga
    78901 ggctcttcca actcttgttt tgaacaagat tcgtggaacc ttcaacgtag tagcagtcaa
    78961 ggcacctggt tttggtgacc gtcgcaaagc catgcttgaa gatatcgcca tcttaacagg
    79021 cggaacagtt atcacagaag accttggtct tgagttgaaa gatgcgacaa ttgaagctct
    79081 tggtcaagca gcgagagtga ccgtggacaa agatagcacg gttattgtag aaggtgcagg
    79141 aaatcctgaa gcgatttcta accgtgttgc ggttatcaag tctcaaatcg aaactacaac
    79201 ttctgaattt gaccgtgaaa aattgcaaga acgcttggcc aaattgtcag gtggtgtagc
    79261 ggttattaag gtcggagccg caactgaaac tgagttgaaa gaaatgaaac tccgcattga
    79321 agatgccctc aacgctactc gtgcagctgt tgaagaaggt attgttgcag gtggtggaac
    79381 agctcttgcc aatgtgattc cagctgttgc taccttggaa ttgacaggag atgaagcaac
    79441 aggacgtaat attgttctcc gtgctttgga agaacccgtt cgtcaaattg ctcacaatgc
    79501 aggatttgaa ggatctatcg ttatcgatcg tttgaaaaat gctgagcttg gtataggatt
    79561 caacgcagca actggcgagt gggttaacat gattgatcaa ggtatcattg atccagttaa
    79621 agtgagtcgt tcagccctac aaaatgcagc atctgtagcc agcttgattt tgacaacaga
    79681 agcagtcgta gccaataaac cagaaccagt agccccagct ccagcaatgg atccaagtat
    79741 gatgggcggg atgatgtaag ctttctatag aaaacaactt ataaaaaaca caaaaggagg
    79801 gaatgactaa cccttctttt tataggctct ttgtcaactg tagtgggttg aagtcagcta
    79861 agctcgagaa aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg
    79921 ttttttgaag ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag
    79981 attattggtc gcttccagtt tggcattaga atagtgtagt tgaagggcgt tgacaatctt
    80041 ttctttatct ttgaggaagg ttttaaagac agtctgaaaa ataggatgaa cctgcttaag
    80101 attgtcctca ataagtccga aaaatttctc tggttcctta ttctggaagt gaaaaagcaa
    80161 gagctgatag agctgatagt gatgtttcaa gtcttccgaa tagctcaaaa gcttgtttaa
    80221 aatctcttta ttggttaaat gcatacgaaa agtaggacga taaaattgct tatcactcag
    80281 tttacggcta tcctgttgaa tgagtttcca gtagcgcttg atagccttgt attcatggga
    80341 ttttcgatga aactgattca tgatttggac acgcacacga ctcatagcac ggctaagatg
    80401 ttgtacaatg tgaaagcgaa gctgtttagc caagccatag taagggctaa acatatccat
    80461 agtaataatt ttgacgcgac atcggacggc tctatcatat ttaagaaagt gatctcggat
    80521 ga
//
LOCUS       DAVDHC010000006        79108 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVDHC010000006 DAVDHC010000000
VERSION     DAVDHC010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79108
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.006"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            371..598
                     /locus_tag="VUR43_000579"
     CDS             371..598
                     /locus_tag="VUR43_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412310.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..3783
                     /gene="nanA"
                     /locus_tag="VUR43_000580"
     CDS             886..3783
                     /gene="nanA"
                     /locus_tag="VUR43_000580"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET5412311.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            4798..5250
                     /locus_tag="VUR43_000581"
     CDS             4798..5250
                     /locus_tag="VUR43_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET5412312.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5269..6606
                     /locus_tag="VUR43_000582"
     CDS             5269..6606
                     /locus_tag="VUR43_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET5412313.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6685..7569
                     /locus_tag="VUR43_000583"
     CDS             6685..7569
                     /locus_tag="VUR43_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5412314.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7569..8402
                     /locus_tag="VUR43_000584"
     CDS             7569..8402
                     /locus_tag="VUR43_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5412315.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8420..10513
                     /gene="nanB"
                     /locus_tag="VUR43_000585"
     CDS             8420..10513
                     /gene="nanB"
                     /locus_tag="VUR43_000585"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET5412316.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10525..11628
                     /locus_tag="VUR43_000586"
     CDS             10525..11628
                     /locus_tag="VUR43_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET5412317.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQLSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            11801..12499
                     /locus_tag="VUR43_000587"
     CDS             11801..12499
                     /locus_tag="VUR43_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET5412318.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            12518..14035
                     /locus_tag="VUR43_000588"
     CDS             12518..14035
                     /locus_tag="VUR43_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET5412319.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            14160..15488
                     /locus_tag="VUR43_000589"
     CDS             14160..15488
                     /locus_tag="VUR43_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5412320.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            15740..16606
                     /locus_tag="VUR43_000590"
     CDS             15740..16606
                     /locus_tag="VUR43_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5412321.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            16622..17461
                     /locus_tag="VUR43_000591"
     CDS             16622..17461
                     /locus_tag="VUR43_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5412322.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            17733..18185
                     /locus_tag="VUR43_000592"
     CDS             17733..18185
                     /locus_tag="VUR43_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET5412323.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            18318..18626
                     /locus_tag="VUR43_000593"
     CDS             18318..18626
                     /locus_tag="VUR43_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412324.1"
                     /translation="MDGQGITVDEMAWIIRGIVNGLIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            18636..18935
                     /locus_tag="VUR43_000594"
     CDS             18636..18935
                     /locus_tag="VUR43_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412325.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            18917..19561
                     /locus_tag="VUR43_000595"
     CDS             18917..19561
                     /locus_tag="VUR43_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET5412326.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            19730..20647
                     /locus_tag="VUR43_000596"
     CDS             19730..20647
                     /locus_tag="VUR43_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET5412327.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            20665..21549
                     /locus_tag="VUR43_000597"
     CDS             20665..21549
                     /locus_tag="VUR43_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5412328.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(21565..22416)
                     /locus_tag="VUR43_000598"
     CDS             complement(21565..22416)
                     /locus_tag="VUR43_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET5412329.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            22616..24673
                     /gene="pbp2b"
                     /locus_tag="VUR43_000599"
     CDS             22616..24673
                     /gene="pbp2b"
                     /locus_tag="VUR43_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET5412330.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            24684..25280
                     /gene="recR"
                     /locus_tag="VUR43_000600"
     CDS             24684..25280
                     /gene="recR"
                     /locus_tag="VUR43_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET5412331.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            25456..26499
                     /locus_tag="VUR43_000601"
     CDS             25456..26499
                     /locus_tag="VUR43_000601"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET5412332.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            26583..27956
                     /locus_tag="VUR43_000602"
     CDS             26583..27956
                     /locus_tag="VUR43_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET5412333.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELGITDLVERKDSLTFKVNFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     RLENEAK"
     gene            27943..28554
                     /locus_tag="VUR43_000603"
     CDS             27943..28554
                     /locus_tag="VUR43_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5412334.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPALSEKRITKEQIEILWQVYQGQREQYLD"
     gene            28645..29349
                     /locus_tag="VUR43_000604"
     CDS             28645..29349
                     /locus_tag="VUR43_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET5412335.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            29568..30941
                     /gene="ftsA"
                     /locus_tag="VUR43_000605"
     CDS             29568..30941
                     /gene="ftsA"
                     /locus_tag="VUR43_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET5412336.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            30958..32217
                     /gene="ftsZ"
                     /locus_tag="VUR43_000606"
     CDS             30958..32217
                     /gene="ftsZ"
                     /locus_tag="VUR43_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET5412337.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            32222..32893
                     /locus_tag="VUR43_000607"
     CDS             32222..32893
                     /locus_tag="VUR43_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET5412338.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            32903..33442
                     /locus_tag="VUR43_000608"
     CDS             32903..33442
                     /locus_tag="VUR43_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET5412339.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            33442..33705
                     /locus_tag="VUR43_000609"
     CDS             33442..33705
                     /locus_tag="VUR43_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET5412340.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            33702..34487
                     /locus_tag="VUR43_000610"
     CDS             33702..34487
                     /locus_tag="VUR43_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET5412341.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVFSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            34496..35284
                     /gene="divIVA"
                     /locus_tag="VUR43_000611"
     CDS             34496..35284
                     /gene="divIVA"
                     /locus_tag="VUR43_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET5412342.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            35632..38424
                     /locus_tag="VUR43_000612"
     CDS             35632..38424
                     /locus_tag="VUR43_000612"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET5412343.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEEF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTSANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            38871..39211
                     /locus_tag="VUR43_000613"
                     /pseudo
     CDS             38871..39211
                     /locus_tag="VUR43_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508814.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            39507..39695
                     /locus_tag="VUR43_000614"
     CDS             39507..39695
                     /locus_tag="VUR43_000614"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412344.1"
                     /translation="MENNDSFTKLKESTQKLFDAQKKRLNNEDRIETAKNNVIAKHCQ
                     TVLSFLVLTSFFVKNCVK"
     gene            39746..40438
                     /locus_tag="VUR43_000615"
     CDS             39746..40438
                     /locus_tag="VUR43_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET5412345.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            40491..42901
                     /locus_tag="VUR43_000616"
                     /pseudo
     CDS             40491..42901
                     /locus_tag="VUR43_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
     gene            43151..43852
                     /locus_tag="VUR43_000617"
     CDS             43151..43852
                     /locus_tag="VUR43_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412346.1"
                     /translation="MVYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDVLNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            43854..46562
                     /locus_tag="VUR43_000618"
     CDS             43854..46562
                     /locus_tag="VUR43_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET5412347.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQCSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(46658..47149)
                     /gene="tpx"
                     /locus_tag="VUR43_000619"
     CDS             complement(46658..47149)
                     /gene="tpx"
                     /locus_tag="VUR43_000619"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET5412348.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(47272..48201)
                     /gene="psaA"
                     /locus_tag="VUR43_000620"
     CDS             complement(47272..48201)
                     /gene="psaA"
                     /locus_tag="VUR43_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET5412349.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(48233..49081)
                     /locus_tag="VUR43_000621"
     CDS             complement(48233..49081)
                     /locus_tag="VUR43_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET5412350.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(49078..49800)
                     /locus_tag="VUR43_000622"
     CDS             complement(49078..49800)
                     /locus_tag="VUR43_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET5412351.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            50091..51983
                     /gene="pepO"
                     /locus_tag="VUR43_000623"
     CDS             50091..51983
                     /gene="pepO"
                     /locus_tag="VUR43_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET5412352.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(52106..52735)
                     /locus_tag="VUR43_000624"
     CDS             complement(52106..52735)
                     /locus_tag="VUR43_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET5412353.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            53751..55973
                     /locus_tag="VUR43_000625"
     CDS             53751..55973
                     /locus_tag="VUR43_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET5412354.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            56003..56446
                     /locus_tag="VUR43_000626"
     CDS             56003..56446
                     /locus_tag="VUR43_000626"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET5412355.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(56713..56899)
                     /locus_tag="VUR43_000627"
                     /pseudo
     CDS             complement(56713..56899)
                     /locus_tag="VUR43_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(57063..57713)
                     /locus_tag="VUR43_000628"
     CDS             complement(57063..57713)
                     /locus_tag="VUR43_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET5412356.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            57825..58667
                     /locus_tag="VUR43_000629"
     CDS             57825..58667
                     /locus_tag="VUR43_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET5412357.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            58743..59180
                     /locus_tag="VUR43_000630"
     CDS             58743..59180
                     /locus_tag="VUR43_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET5412358.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            59249..59551
                     /locus_tag="VUR43_000631"
     CDS             59249..59551
                     /locus_tag="VUR43_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412359.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(59642..60715)
                     /locus_tag="VUR43_000632"
     CDS             complement(59642..60715)
                     /locus_tag="VUR43_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET5412360.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVTTVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            60871..61548
                     /locus_tag="VUR43_000633"
     CDS             60871..61548
                     /locus_tag="VUR43_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5412361.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            61541..62515
                     /locus_tag="VUR43_000634"
     CDS             61541..62515
                     /locus_tag="VUR43_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET5412362.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(62564..64507)
                     /gene="thrS"
                     /locus_tag="VUR43_000635"
     CDS             complement(62564..64507)
                     /gene="thrS"
                     /locus_tag="VUR43_000635"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET5412363.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(64565..64888)
                     /locus_tag="VUR43_000636"
     CDS             complement(64565..64888)
                     /locus_tag="VUR43_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET5412364.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTNQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            65747..66376
                     /locus_tag="VUR43_000637"
     CDS             65747..66376
                     /locus_tag="VUR43_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET5412365.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAES
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            66517..66786
                     /gene="rpsO"
                     /locus_tag="VUR43_000638"
     CDS             66517..66786
                     /gene="rpsO"
                     /locus_tag="VUR43_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET5412366.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            67602..68216
                     /locus_tag="VUR43_000639"
     CDS             67602..68216
                     /locus_tag="VUR43_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET5412367.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(68508..69257)
                     /locus_tag="VUR43_000640"
     CDS             complement(68508..69257)
                     /locus_tag="VUR43_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET5412368.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            69390..71726
                     /locus_tag="VUR43_000641"
     CDS             69390..71726
                     /locus_tag="VUR43_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET5412369.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNLAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GSSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQEKK"
     gene            72255..73718
                     /locus_tag="VUR43_000642"
     CDS             72255..73718
                     /locus_tag="VUR43_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET5412370.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSAFLTEGDKQRLQAKIQEINYE"
     gene            73711..74139
                     /locus_tag="VUR43_000643"
     CDS             73711..74139
                     /locus_tag="VUR43_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5412371.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKPPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            74117..74566
                     /locus_tag="VUR43_000644"
     CDS             74117..74566
                     /locus_tag="VUR43_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5412372.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            74594..74905
                     /locus_tag="VUR43_000645"
     CDS             74594..74905
                     /locus_tag="VUR43_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET5412373.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            74931..76016
                     /locus_tag="VUR43_000646"
     CDS             74931..76016
                     /locus_tag="VUR43_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET5412374.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILRKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            76027..76722
                     /locus_tag="VUR43_000647"
     CDS             76027..76722
                     /locus_tag="VUR43_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET5412375.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            76759..78729
                     /gene="tkt"
                     /locus_tag="VUR43_000648"
     CDS             76759..78729
                     /gene="tkt"
                     /locus_tag="VUR43_000648"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET5412376.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSIELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
BASE COUNT        23855 a        14165 c        17580 g        23508 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg atttttattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaataaggta taataaattt
      241 actaacactt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtgtaaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgt cttggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgccaagg ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1381 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1441 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1501 aattctgtga ctttcacagt tgaaaaacca acagcagaat tgccaaatgg tcgagttcgc
     1561 ctgtatgtta atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat
     1621 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1681 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgccttaag cccagaagaa
     1741 gttcagacga gaagccaact atttgaaaga ggtgatttgg agaagaaact tccagaaggt
     1801 gcgaaaatct cagagaaaga agacgtcttt gaagggggaa tgaacaacaa accaaataaa
     1861 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aagaaatcga tggaaaaacc
     2221 tatcaaatcc tctatcgtga gggagaaaag gaagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggaaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 aaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaaaatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacacttc aattggcaaa tggtaaaaca
     3361 gcgactttcc taacccagta tgatagcaag accttgttgt ttgcagtaga taaggaagat
     3421 atcggacagg aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct
     3481 gtaaatctag caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat
     3541 gaagttccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3601 gagtataagg gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa
     3661 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3721 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     3781 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggtttttaa
     3841 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     3901 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     3961 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataaa
     4021 ttcaatatat tatacgacta ttaaccttat cttctcctaa aattgacttt cttgttttct
     4081 tatcttgtct actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4141 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4201 atactaaaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg
     4261 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
     4321 agccaaagag tctattagtg ttagaataat agattagaat tattttagaa aaacgaagtg
     4381 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
     4441 agggcgactt ccttcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
     4501 cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
     4561 tgaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcttt
     4621 gaggttgtag ataagactga cgtatataat ccaaggtgaa gcgactgtgg tttgaagaga
     4681 ttttcaaaga gtataggcta gagagtagtg tttttatgtc cttctagtag aaaatgctag
     4741 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
     4801 attattacaa aaattagccg tttaggaact tatgtgggag taaatccaca ttttgcaaca
     4861 ttaatagatt ttttagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc
     4921 gatggtaatc gattgtttgg gaattgcttt acttatctag cagatggtca agcaggggct
     4981 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
     5041 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
     5101 attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg tgaatgcctc
     5161 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
     5221 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     5281 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     5341 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     5401 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     5461 ttcatgcaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     5521 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     5581 cctaaccaag taatggaaat ggtcaactca gatgctttgg ttccgctaaa tgattctatc
     5641 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     5701 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     5761 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     5821 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     5881 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     5941 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     6001 tataaagaaa tctcacctca agattctttg aactttaatg tccttcaaca agctaccttg
     6061 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     6121 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     6181 tctgataaag accaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     6241 aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     6301 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     6361 gcagcctata aagaaaatga aactcgtaag aaatttaaac atgctgaaga agtaattact
     6421 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     6481 atgttaacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     6541 gatcctatga aagcagcaaa agaagcagaa aaacaattaa acgatttatt tgaggctgtt
     6601 cagtagatgt aaaagactag aaaataggtg ggctagtgag ctgaaaagct ctagcccaat
     6661 cttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     6721 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     6781 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     6841 aactataaag ctgtgctgtc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     6901 tggaccgttt tctcattagt tggtcaagtt ttagtagggt ttgtattggc tttagctctt
     6961 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     7021 cctaccatcg ttattgcctt ctcttggcag tggattctaa acggggttta tggctactta
     7081 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     7141 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     7201 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     7261 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     7321 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     7381 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttacaac
     7441 ctgggttggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     7501 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     7561 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     7621 ttggtgcgac catcgttgca attttcccat tggtatggat tatcatatct tctgtcaaag
     7681 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     7741 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     7801 ttgccttggc tacaaccctc attgcgatta ttatttctgc tatggcagcc tatggtattg
     7861 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctacattt
     7921 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     7981 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     8041 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     8101 gtgcaaataa atttgttacg ttttataagg ttgtgctacc gattgtagca ccaggtattg
     8161 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     8221 taattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     8281 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     8341 ttttcttctc tatcatccaa aataagattg caagtggatt atcagaagga tctgtgaagt
     8401 agacgaaaga aggaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt
     8461 tgtaggcatt agtcttttaa tgggagtccc cactttgatt catgcgaatg aattaaacta
     8521 tggtcaactg tccatatctc ctatttttca aggaggttca tatcaactga acaataagag
     8581 tatagatatc agctctttgt tattagataa attgtctgga gagagtcaga cagtagtaat
     8641 gaaatttaaa gcagataaac caaactctct tcaagctttg tttggcctat ctaatagtaa
     8701 agcaggcttt aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt
     8761 agaaataaga gacgcccaaa agggaataaa ttatttattt tctagaccag cttcattatg
     8821 gggaaagcat aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga
     8881 taaaacatac acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt
     8941 tttgccaatt tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga
     9001 aggtaaggaa cattacctcg caaaaggaag tattggtgaa atcagtctat ttaacaaagc
     9061 aattagtgat caggaagttt caaatattcc cttgtcaaat ccatttcagt taattttcca
     9121 atcaggagat tctactcaag ctaactattt tagaataccg acactatata cattaagtag
     9181 tggaagagtt ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa
     9241 gattaatatt gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt
     9301 tgctatgaag tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt
     9361 aaagaatagt caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa
     9421 aaaatctggg aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa
     9481 tgcaaataaa gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa
     9541 gaagaatgga gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga
     9601 aacaactaat aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg
     9661 aaagtcttta acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaag
     9721 gcataatgga aaacaggttc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac
     9781 tcctactaat tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt
     9841 taagttgttg cctccgttct taggagaaaa acataatgga acttacttgt gtcctggaca
     9901 aggtttagca ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact
     9961 aacctatctc atttcggatg atagtggtca aacatggaag aaatcctcag cttcaattcc
    10021 gtttaaaaat gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac
    10081 attctttaga accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac
    10141 atggtcgaaa gtttcgtata ttgatggaat tcaacaaact tcatatggca cacaagtatc
    10201 tgcaattaaa tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa
    10261 ttctagaagt ggccgtaagg gaggccaatt agttgtcggt ttggtcaata aagaagatga
    10321 tagtattgat tggagatacc actatgatat tgatttgcct tcgtatggtt atgcctattc
    10381 tgcgattaca gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg
    10441 gtcgagaaat gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga
    10501 tttaacaaaa taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt
    10561 ggagctgaat tggctcgcta catgcaaaag aatgatggag cagagattac tcttctctat
    10621 gatccagata atgcagaggc gattgcagaa gaattgggag caaaagtagc aagttcctta
    10681 gatgagttgg tttctagcga tgaagtagat tgtgttatcg tcgcaactcc aaataatctt
    10741 cataaggaac cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca
    10801 attgcgcttt cttatcaaga ttgtcgcgag atggtagatg cgtgtaaaga aaacaatgta
    10861 acctttatgg caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc
    10921 attaatcaag gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa
    10981 gaacaacaac tgtcagtatc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat
    11041 caccacatcc atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta
    11101 accatgacag gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg
    11161 atttttgtca atatggaatt ttctaataag cgttttgcct tgttagaatg gggttcagct
    11221 tatcgttggg gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac
    11281 ttattcaact gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac
    11341 gaatcgcaag aagaagatga tgatcggact cgtatctatc atagtacaga gatggatgga
    11401 gcaattgctt atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat
    11461 aaagaaatgc gctatctgca tgagattatg gaaggagctc cagtatcaga agaatttgca
    11521 aaacttttga caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag
    11581 tctatgtttg aagatcgcaa agtaaaattg tcagaaattg taaaataaat tttggtattc
    11641 tcctattata ggtcgacttg ctcctctgaa agtactttta gaggagctgt ttgacttggc
    11701 tagtttttga aactgaaatc tattatacta caaactattg aaagcgtttt aattttaagg
    11761 tataataatc tcatagaaat aaagaaaagg aggaaagagg atgccacaga ttagcaaaga
    11821 agccttgatt gagcaaatca aagatggaat catcgtttct tgtcaggctc ttcctcatga
    11881 accgctttat acagaagcgg gaggggtgat tcccttgctg gtcaaagcgg ctgagcaagg
    11941 tggagcagtc ggtatccgag caaacagtgt tcgcgatatc aaggaaatta aggaagtcac
    12001 taaacttcca atcattggga ttatcaaacg tgattatcca cctcaggaac ccttcatcac
    12061 ggctactatg aaagaagttg atgaattggc agaactggac atcgaggtga ttgctctgga
    12121 ttgtaccaag cgtgaacgct acgatggttt ggaaattcaa gagttcattc gtcaggttaa
    12181 ggagaaatat cctaatcagc ttttgatggc tgatactagt atcttcgaag aagggctagc
    12241 agctgtagaa gcaggaattg actttgtcgg aacaacctta tcaggctaca catcctacag
    12301 tccaaaagta gacggtccag attttgaatt gattaagaaa ctctgtgatg ccggtgtaga
    12361 tgtcattgca gaaggaaaaa ttcatacacc agaacaagcc aaacaaatcc ttgaatatgg
    12421 agtgcgaggc atcgttgttg gtggcgccat tactagacca aaagagatta cagaacgctt
    12481 cgttgctagt cttaaataag atgtgagggg gagttttatg tttaaagttt tacaaaaagt
    12541 tggaaaagct tttatgttac ctatagctat acttcctgca gcaggtctac ttttggggat
    12601 tggtggtgca ctttcaaacc caaccacgat agcaacttat ccaatactag acaatagtat
    12661 ttttcaatca atattccaag taatgagctc tgcaggagag gttgtattca gtaatttgtc
    12721 actacttctc tgtgtgggat tatgtattgg cttagcgaaa cgagataaag gaaccgctgc
    12781 gttagcagga gtaactggtt acttagttat gactgcaacg atcaaagctt tggtaaaact
    12841 ttttatggca gaaggatctg caattgatac tggagttatt ggagcattag ttgtcggaat
    12901 agttgccgta tatttgcaca accgatataa caatattcaa ttaccttccg ctttaggatt
    12961 ctttggaggt tcacgcttcg ttcctattgt tacatcgttc tcttctatct tgattggctt
    13021 tgtcttcttt gttatttggc cacctttcca acaacttctt gtttctacag gtggatatat
    13081 ttctcaggcg ggtccaattg gaacttttct atatggattt ttaatgagac tttctggagc
    13141 agtaggctta catcatataa tttaccctat gttttggtat actgaacttg gtggtgttga
    13201 aactgttgca ggacaaacag tggttggagc tcaaaaaata ttttttgctc aattagccga
    13261 tccggcccat tctggattat ttacagaagg aacaaggttt tttgcaggtc gtttctcaac
    13321 aatgatgttc ggtttaccgg ctgcctgttt agcgatgtac catagtgttc ctaaaaatcg
    13381 tcgtaaaaaa tacgcgggtt tgttttttgg agttgcttta acatctttta ttaccggtat
    13441 tacagaacca attgaattta tgtttctatt cgtcagtccg gttctatatg ttgttcacgc
    13501 attccttgat ggtgttagct tctttattgc agacgtctta aatatttcaa taggaaacac
    13561 attttcagga ggtgtaatcg atttcacttt atttggaatt ttgcagggga acgctaagac
    13621 gaattgggtt cttcagattc caattggact tatttggagt gttttgtatt atattatttt
    13681 tagatggttc attactcaat tcaacgttct aacgccagga cgaggagaag aagtagattc
    13741 taaagaaatt tctgaatccg cagattcaac ttcaaatact gcagattatt taaaacagga
    13801 tagcctacaa attatcagag ccttgggtgg atcaaataat atagaagatg tagatgcttg
    13861 tgtgacacgt ttacgtgtag ctgtaaaaga agttaatcaa gttgataaag cacttttaaa
    13921 acaaattggt gcagttgatg tcttagaagt gaagggtggc attcaagcaa tctatggagc
    13981 aaaagcaatc ttatataaaa atagtattaa tgaaatttta ggtgtagatg attaagtact
    14041 tactgactta ataaaaaaca gaggagagtg atggatgagt aggatgaaat gaaatcgcat
    14101 acaagaaata aagaactcat tatccaagtt ggatacgctt attacatagg agaatacaaa
    14161 tgaaatttag aaaattagct tgtacagtac ttgcgggtgc tgcggttctt ggtcttgctg
    14221 cttgtggcaa ttctggcgga agtaaagatg ctgccaaatc aggtggtgac ggtgccaaaa
    14281 cagaaatcac ttggtgggca ttcccagtat ttacccaaga aaaaactggt gacggtgttg
    14341 gaacttatga aaaatcaatc atcgaagcgt ttgaaaaagc aaacccagat ataaaagtga
    14401 aattggaaac catcgacttc aagtcaggtc ctgaaaaaat cacaacagcc atcgaagcag
    14461 gaacagctcc agacgtactc tttgatgcac caggacgtat catccaatac ggtaaaaacg
    14521 gtaaattggc tgagttgaat gacctcttca cagatgaatt tgttaaagat gtcaacaatg
    14581 aaaacatcgt acaagcaagt aaagctggag acaaggctta tatgtatccg attagttctg
    14641 ccccattcta catggcaatg aacaagaaaa tgttagaaga tgctggagta gcaaaccttg
    14701 taaaagaagg ttggacaact gatgattttg aaaaagtatt gaaagcactt aaagacaagg
    14761 gttacacacc aggttcattg ttcagttctg gtcaaggggg agaccaagga acacgtgcct
    14821 ttatctctaa cctttatagc ggttctgtaa cagatgaaaa agttagcaaa tatacaactg
    14881 atgatcctaa attcgtcaaa ggtcttgaaa aagcaactag ctggattaaa gacaatttga
    14941 tcaataatgg ttcacaattt gacggtgggg cagatatcca aaactttgcc aatggtcaaa
    15001 catcttacac aatcctttgg gcaccagctc aaaatggtat ccaagctaaa cttttagaag
    15061 caagtaaggt agaagtggta gaagtaccat tcccatcaga cgaaggtaag ccagctcttg
    15121 aataccttgt aaacgggttt gcagtattca acaataaaga cgacaagaaa gtcgctgcat
    15181 ctaagaaatt catccagttt atcgcagatg acaaggagtg gggacctaaa gacgtagttc
    15241 gtacaggtgc tttcccagtc cgtacttcat ttggaaaact ttatgaagac aaacgcatgg
    15301 aaacaatcag cggctggact caatactact caccatacta caacactatt gatggatttg
    15361 ctgaaatgag aacactttgg ttcccaatgt tgcaatctgt atcaaatggt gacgaaaaac
    15421 cagcagatgc tttgaaagcc ttcactgaaa aagcgaacga aacaatcaaa aaagctatga
    15481 aacaatagtc cttagttatt ctataaaaag tagtttttta aagaacctaa gagtgtatac
    15541 ccccttttcc ctctacacag atagtgtaag aaaagggggc ttttgtttaa aatgtaagaa
    15601 actgtcacga aattaaaatg aagttcttac ataagcgaat cataaaaaat ttcattttga
    15661 ttttaaaaca gttcaagaaa gtcaaaaaat tattctattt gaaagagagg tgccgactgt
    15721 gaaagtcaat aaaatccgta tgcgggaaac agtgatttcc tacgctttcc tagcaccagt
    15781 attattcttc tttgtcatct ttgtgttggc tccgatggtg atgggcttca ttacaagttt
    15841 ctttaactac tcaatgacta aatttgagtt tgtaggcttg gataactata tccgtatgtt
    15901 taaagatcct gtctttacaa aatctctgat taacacagtt attttggtta ttggatctgt
    15961 accagttgtt gttctattct cactctttgt agcatctcag acctatcatc aaaatgtcat
    16021 tgccagatcc ttctaccgtt tcgtcttctt ccttcctgtt gtaacgggta gtgttgccgt
    16081 gacagttgtt tggaaatgga tttatgaccc actatcaggg attctaaact ttgtccttaa
    16141 gtccagccac atcatcagcc aaaacatttc ttggttggga gataaaaact gggcattgat
    16201 ggcgattatg attattctct tgaccacttc agttggtcag cccatcatcc tttatatcgc
    16261 tgccatgggg aatattgaca attcactggt tgaagcggcg cgtgttgatg gtgcaactga
    16321 gtttcaagtt ttttggaaga ttaaatggcc aagccttctt ccaacaactc tttatattgc
    16381 aatcatcaca acaattaact cattccagtg ttttgccttg attcagcttt tgacatctgg
    16441 tggtccaaac tactcaacaa gtaccttgat gtactacctt tacgaaaaag ccttccaatt
    16501 gacagaatac ggctatgcca acacaattgg tgtcttcttg gcagtcatga ttgctatcgt
    16561 aagctttgtt caatttaaag tacttggaaa cgacgtagaa tactaaagaa aggagacagc
    16621 tatgcaatct acagaaaaaa aaccattaac agcctttact gttatttcaa caatcatttt
    16681 gctcttgttg actgtgctgt tcatctttcc attctactgg attttgacag gggcattcaa
    16741 atcacaacct gatacaattg ttattcctcc tcagtggttc cctaaaatgc caaccatgga
    16801 aaacttccaa caactcatgg tgcagaaccc tgccttgcaa tggatgtgga actcagtatt
    16861 tatctcattg gtaaccatgt tcttagtttg tgcaacctca tctctagcag gttatgtatt
    16921 ggctaaaaaa cgtttctatg gtcaacgcat tctatttgct atctttatcg ctgctatggc
    16981 gcttccaaaa caagttgtcc ttgtaccatt ggtacgtatc gtcaacttca tgggaatcca
    17041 cgatactctc tgggcagtta tcttgccttt gattggatgg ccattcggtg tcttcctcat
    17101 gaaacaattt agtgaaaata ttcctacaga gttgcttgaa tcagctaaaa tcgacggttg
    17161 tggtgagatt cgtaccttct ggagtgtagc cttcccgatt gtgaaaccag ggtttgcagc
    17221 ccttgcaatc tttaccttca tcaatacttg gaatgactac ttcatgcaat tggtaatgtt
    17281 gacttcacgt aacaatttga ccatctcact tggggttgcg accatgcagg ctgaaatggc
    17341 aaccaactat ggtttgatta tggcaggagc tgcccttgct gctgttccaa tcgtcacagt
    17401 cttcctagtc ttccaaaaat ccttcacaca gggtattact atgggagcgg tcaaaggata
    17461 atactctgag aaaatctctt caaactacgt cagcctcacc ttgccatact taagtattgc
    17521 ctgcggttag cttcctagtt tgttcttcaa ttttcattga gtataggaaa atcaatctat
    17581 caagatacag aagtatattt tatagattta gagaatatag aggttataag tgtctacaaa
    17641 atggagggta tgcagttact ttatgaagtt ttgtcagaca cttataaact taagaatggt
    17701 tttagttaac tatcagaaac gaaggaaaga gtatgatttt tgacgatttg aaaaacatca
    17761 ccttttacaa agggattcat cctaatttag acaaggctat cgactatctc taccaacatc
    17821 gtaaggattc tttcgaatta ggaaagtatg atattgatgg agataaagtc tttctagttg
    17881 ttcaggaaaa tgtcctcaat caagctgaaa atgatcaatt tgagtatcat aagaactatg
    17941 cagatttgca tttgctggta gaaggacatg aatattcgag ctacggttca cgtatcaaag
    18001 acgaggcagt agcattcgac gaagcgagtg acattggctt tgttcattgt catgaacact
    18061 acccactctt gttgggttat cacaattttg cgattttctt cccaggtgag ccacatcagc
    18121 caaatggtta tgcaggcatg gaagaaaagg ttcggaaata tctctttaaa attttgattg
    18181 attaaaaata ggatgaattg tttttttgta aagctttgac aatactctac catgaaattg
    18241 atctttgtga ggtagggaaa tgagaataaa atatttaaaa attggtatct tctaagtatg
    18301 ctgcaagagc tagtttcttg gatggacagg gaattacagt tgatgagatg gcttggataa
    18361 ttaggggcat tgtgaatgga ttgattggta gatacataaa attaggtact tatgcagcca
    18421 agtatggtat tagtatggcg cgttcgatct taagtagggc agctgcaact gcagcagcaa
    18481 gagtaggatt atcgaccaag atttctggat ggattttacg agtagctgtg aatgtagctg
    18541 atgtatatgg taattttgcc aacaatattg ctgcagcttg ggatgcacat gataaaattc
    18601 ctaacaatgg tcgtataaac ttttaaaatg cgagaatgaa agcactttgt atttttttat
    18661 tgaatatgtt agcttggaca gtgcttgcaa tgataattcg tggagggcta gatggatttg
    18721 atgagcatac ttggagtact attttaattg cttcgctgtt cggggtatat gattataagc
    18781 ccatagataa aaatagaaaa aagtccaaaa gaaaaaagaa aaaagaaaaa atagatttgt
    18841 tcatggtagg gacttatgaa agctttactg acaaaaaaga aaacagttta caaagaaaaa
    18901 tgatggagga gcaaacatgg cacaaaaagg agtaagcctt atcaaggcag catttgatac
    18961 agacaacttt ctcatgcgtt ttagtgagaa agtcttggac atcgtgacag ccaatcttct
    19021 ttttgtcgtc tcttgtttgc ccatcgtgac gattggagtg gctaaaatca gcctctacga
    19081 gaccatgttc gaagttaaga agagcagacg ggtgcctgtt tttaaaatct atctaagatc
    19141 tttcaagcaa aatctgaaac taggtcttca gctgggttta atggagttag gaattgtgtt
    19201 tcttaccctt tcagatctct atcttttctg gggtcaaaca gctctgccct tccaattgct
    19261 gaaagccatt tgtttaggta ttctgatttt tcttactatc gtgatgctgg ctagttaccc
    19321 tatcgcggca cgttatgacc tatcttggaa agaaattctt caaaaaggat tgatgttggc
    19381 tagttttaac tttccttggt tcttcctcat gttagccatt cttgtcctca ttgtgatggt
    19441 tctttatctg tccgccttca gtctactctt aggtggctca gtcttcttac tttttgggtt
    19501 tggactattg gtctttatcc agactggatt gatggagaaa attttcgcaa aataccaata
    19561 ggagccttat ttctgaaact actttcaaac gctccaaacg ctattctata agcgagaaac
    19621 taaaatctaa gtgtctataa gatattgaaa gccttttcgg taaagtgtat actaaagaag
    19681 taaagaaaaa tctgctttag cagaaaataa aaataatagg agaaaatcta tgtcagattt
    19741 gaaaaaatac gaaggtgtca ttccagcctt ctacgcatgt tatgatgaac aaggagaagt
    19801 aagcccagaa cgtacgcgtg ccttggttca atacttcatt gataaaggtg ttcaaggtct
    19861 ttatgtcaat ggttcttctg gtgaatgtat ctaccaaagt gttgaagacc gcaagttaat
    19921 cttggaagaa gtcatggcgg tagccaaagg taaattgacc atcattgctc atgttgcctg
    19981 caacaatact aaagatagta tggaacttgc tcgccatgct gaaagcttgg gagtagatgc
    20041 tattgcaacg attccaccaa tttatttccg cttgccagaa tactcagttg ccaaatactg
    20101 gaacgatatc agttctgcag ctccaaacac agactacgtg atttacaaca ttcctcaatt
    20161 ggcaggggtt gctttgactc caagccttta cacagaaatg ttgaaaaatc ctcgtgttat
    20221 cggtgttaag aactcttcta tgccagttca agatatccaa acctttgtca gccttggtgg
    20281 ggaagaccat atcgtcttta atggtcctga tgagcagttc ctaggaggac gcctcatggg
    20341 tgctagggct ggtatcggtg gtacttatgg tgctatgcca gaactcttct tgaaactcaa
    20401 tcagttgatt gcggataagg acctagaaac agcgcgtgaa ttgcagtatg ctatcaacgc
    20461 aatcattggt aaactcactt ctgctcatgg aaatatgtac ggtgtcatta aagaagtctt
    20521 gaaaatcaat gaaggcttga atattggatc tgttcgttca ccattgacac cagtgactga
    20581 agaagatcgt ccagttgtag aagcggctgc tgccttgatt cgtgaaacca aggagcgctt
    20641 cctctaatct aaaaggaggt atttatgaca tactacgttg caattgatat cggtggaacc
    20701 aacatcaagt atggtttggt tgatcaagag gggcaacttc ttgaatcgca tgaaatgcca
    20761 actgaggcgc ataagggtgg acctcatatc ttacaaaaga ccaaagatat cgtagctagt
    20821 tatttagaaa aaggcccagt agcaggtgtt gccatatctt ctgctgggat ggtggatccg
    20881 gataagggtg agattttcta tgctgggcct caaatcccta actacgcagg cacccagttc
    20941 aaaaaggaaa tcgaagaaag ctttactatt ccttgtgaga ttgaaaatga tgtcaactgt
    21001 gcaggtcttg ctgaggcagt atctggttca ggcaagggag caagtgtgac actttgcttg
    21061 accattggaa ccggtatcgg tggttgcttg attatggata ggaaagtctt ccatggtttt
    21121 agcaattcag cctgtgaagt cgggtatatg catatgcagg atggagcttt tcaggatctc
    21181 gcttctacaa cagctttagt gaaatatgta gctgaagccc atggagaaga tgttgatcag
    21241 tggaatggcc gacgtatctt taaggaagct actgaaggaa acaaaatctg catggaaggt
    21301 attgaccgta tggttgacta tctaggaaaa ggtctggcaa atatttgtta tgtggccaat
    21361 ccagaagtgg ttattcttgg tggtggtatc atggggcaag aggctatcct caaacctaag
    21421 atccgcacag ccttgaaaga ggcattggta ccaagtttag cagaaaaaac acgattagaa
    21481 tttgcccatc accaaaatac agcagggatg ttgggtgcat attatcattt taagacaaaa
    21541 caatcctagt ttggctcagc caaactagga ttttcttaca cgtttttgtc tacgatagcc
    21601 gttgagtttt ttattttccc agtagctatt aaagattttt tccttgcttt cgcgattgat
    21661 ttccaaaaag taggcataaa tcaaatcgat aaagaagagc ataggaagtt gagcggatat
    21721 tcgttggatg taggagggtt ggctgtgggt ggctacaaga acagtctctg tataggtctg
    21781 gctatcttta ttgggaacac ttgtaaagag tacagtcttt gcccccatct ccttggcatc
    21841 taatagacta tctaaaatag aaggagttga gcctgaaagt gagaaaccca gtactagaca
    21901 attttcatcc atgatgctgg ttgtccaggc aaagccgtct tggtctgtca aagcttcgca
    21961 gaccacacct agtcgcataa aacgtaattt catttcacgg gcgacgaggc cagaactccc
    22021 tgttccaaag aagtagatac gctcagcatc ttcgattagc tgggcaattc gctctagttg
    22081 gatttcgtca atcaagtctt gtgtttgttc cctcatattg ctataacttc tgaggactcg
    22141 tttggtcagt ggactatgct tggagacttg gttggcttga ttttctgcct gatgttggta
    22201 ttggaaaata aattctcggt agccagtaaa gccacacttt ttagcaaagc gggtcaaagc
    22261 agcttgagaa atatgtaatt tttgggtgac ttgttgagaa gataaatcat ctgtaatcgt
    22321 ttcagcttgc aaaaaatagc gagcgatttc ttgctctagg tctgtcattt cttcaaaatg
    22381 tgaatcaatg atagttgcga tatctggttt gtccataggg aaagctcctt tacatgggtc
    22441 atactggaag actagatcag ggaatagtca cacttcatta taacacataa tataaggata
    22501 gataaataaa aacgcatctc tgttttaaaa acgaaaaaat cgaaaaagct tctctctttt
    22561 ccataatttt ctactcaaat tgtggtacaa ttaagagtaa gattttaagt tagaaatgag
    22621 actgatttgt atgagaaaat ttaacagcca ttcgattccg attcggctta atttattgtt
    22681 ttcaatcgtc attttactct ttatgaccat tattggtcgt ttgttgtata tgcaggtttt
    22741 gaacaaggat ttttacgaaa aaaagctagc ctcagctagt cagaccaaga ttacaagcag
    22801 ttcagcccgt ggggaaattt atgatgctag tggaaaacct ttggtagaaa atacgttaaa
    22861 gcaggttgtt tcctttacgc gtagcaataa aatgacggct acagacttaa aagaaacagc
    22921 taaaaagtta ctgacttatg tgagcatcag ttctccaaat ttgacagaac gccagctggc
    22981 ggattactat ttggctgatc ctgaaatcta taaaaaaaca gtggaagctc tcccaagtga
    23041 gaaacgcttg gattcagatg gcaatcgtct atccgaatca gaactgtata acaatgcggt
    23101 cgatagtgtc caaacaagtc aactaaacta tacagaggat gaaaagaaag aaatctatct
    23161 ttttagtcag ttaaatgctg ttggaaactt tgcgacagga accattgcta cagatcctct
    23221 aaatgattct caggtggctg ttattgcctc tatttcaaag gagatgcctg gcattagtat
    23281 ttctacttct tgggatagaa aggttttgga aacttccctt tcttctatag ttgggagtgt
    23341 atccagtgaa aaagctggtc tcccagcgga agaagcagaa gcctatctta aaaaaggcta
    23401 ttctctaaat gatcgtgtag gaacctccta tttggaaaag caatatgaag agaccttaca
    23461 aggaaaacgc tcggtaaaag aaatccatct ggataaatat ggcaatatgg aaagcgtgga
    23521 tacaattgag gaaggtagta agggaaacaa tatcaaactg accattgatt tggctttcca
    23581 agatagcgtg gatgctttac tgaaaagtta tttcaattcc gagctagaaa atggtggagc
    23641 caagtattct gaaggtgtct atgcagtcgc ccttaaccca aaaacaggtg cggttttgtc
    23701 tatgtcaggg attaaacatg acttgaaaac gggagagttg acgcctgatt ccttgggaac
    23761 ggtaaccaat gtctttgttc caggttcggt tgtcaaggcg gcgaccatca gctcaggttg
    23821 ggaaaatgga gtcttgtcag gaaaccagac cttgacagac cagtccattg tcttccaagg
    23881 ttcagctccc atcaattctt ggtatactca ggcttacggt tcattcccta tcacagcggt
    23941 ccaagctctg gagtattcat caaataccta tatggtccaa acagccttag gtcttatggg
    24001 gcaaacctat caacccaata tgtttgtcgg caccagcaat ctagagtctg ctatggagaa
    24061 actgcgttca acctttggcg aatatggctt gggtactgcg acaggaattg acctaccaga
    24121 tgaatctact ggatttgttc ccaaagagta tagctttgct aattacatta ctaatgcctt
    24181 tgggcagttt gataactata cgccgatgca gttggctcag tatgtagcaa ctattgcaaa
    24241 taatggtgtt cgtgtggctc ctcgtattgt tgaaggcatt tatggtaata atgataaggg
    24301 aggactgggt gacttgattc agcaactgca accgacagag atgaataagg tcaatatatc
    24361 cgactccgat atgagcatct tgcaccaagg tttttatcag gttgcccatg gtactagtgg
    24421 attgacaact ggacgtgcct tttcaaatgg cgccttggta tccattagcg gaaaaacagg
    24481 tacagccgaa agctatgtgg cagatggtca gcaagcaacc aataccaatg cggtggccta
    24541 tgccccatct gataatcccc aaatcgctgt tgcagtggtc tttcctcata ataccaatct
    24601 aacaaatggt gtaggacctt ccattgcgcg tgacattatc aatctgtatc aaaaatacca
    24661 tccaatgaac tagaaaggaa attatgcttt atccaacacc tattgccaag ttgattgaca
    24721 gttattctaa gttaccaggt atcgggatta agacggctac gcgtctggcc ttttatacga
    24781 ttgggatgtc tgctgatgat gtcaatgaat ttgcaaaaaa tctcctttct gctaagagag
    24841 aattgacata ttgttctatt tgtggacgtt tgacagacga cgatccttgt tctatctgta
    24901 ctgatccgac tcgtgaccag acaacaattt tagttcttga ggatagtaga gatgtggcag
    24961 ccatggaaaa tatccaagaa taccatggac tctatcatgt ccttcatggc ctcatttctc
    25021 ctatgaatgg tatcagtccg gacgatatca atctcaagag ccttatgact cgtcttatgg
    25081 atagtgaagt ttcagaagtg attgtggcga ctaatgctac agcggatggt gaagcgactt
    25141 ccatgtatct ttcacgtttg ctcaagccgg ctggtatcaa ggttacgcgt ctagcacgag
    25201 gtctcgctgt gggagcggac attgagtatg cggacgaagt gacactctta cgagcgattg
    25261 aaaatcggac agagttgtaa gtgtaggcaa atttacgaac tccattcatt tataaaaaat
    25321 caaagaggct gaaaatcgtt cctatcggcc tctttttgta tagtgtgatg agtaggatca
    25381 ggttcaagtt ttaaaaaacc aagcaaatat gatatactaa agagcgagta ttctagtaga
    25441 attaggacaa ataatatgaa acaaacgatt attcttttat atggtggacg gagtgcggaa
    25501 cgcgaagtct ctgtcctttc agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc
    25561 acagtcaaga ctttctttat cagtcagtca ggtgacttta tcaaaacaca ggaatttagt
    25621 catgctccgg ggcaagaaga ccgtctcatg accaatgaaa ccattgattg ggataagaaa
    25681 gttgcaccaa gtgctatcta cgaagaaggt gcagtggtct ttccagtcct tcacgggcca
    25741 atgggagaag atggctctgt tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt
    25801 tgcaacattt tgtcatcaag tcttgccatg gataaaatca cgactaagcg tgttctggaa
    25861 tctgctggta ttgcccaagt tccttatgtg gctatcgttg aaggcgatga tgtgactgct
    25921 aaaatcgctg aagtggaaga aaaattggct tatccagtct tcactaagcc gtcaaacatg
    25981 gggtctagtg tcggtatttc taagtctgaa aaccaagaag aactccgtca agccttaaaa
    26041 cttgccttcc gatatgacag ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt
    26101 gaggttggcc tcttgggtaa ctacgatgtc aagagcacgc tacctggaga agttgtcaag
    26161 gacgttgcct tttatgacta cgatgccaag tatattgata acaagattac tatggatatt
    26221 cctgccaaaa tcagtgatga tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc
    26281 cgtgccattg gtggccttgg tctatctcgt tgcgatttct tctatacaga taagggagag
    26341 atttttctca acgagctcaa taccatgcca ggttttaccc agtggtctat gtacccacta
    26401 ctttgggaca atatggggat cagctaccca gaactaatcg agcgtttggt tgaccttgcc
    26461 aaggaaagtt ttgacaagcg cgaagcgcat ttgatataaa atgaaagaga gggtagaagc
    26521 cagaaccatc actgcacggt gactagagtt ctcggacttc agcccttttt aaaggagtag
    26581 aaatgaaatt aacaatccat gaaattgccc aagttgttgg agccaaaaat gatatcagta
    26641 tctttgagga cacccagtta gaaaaagctg agtttgatag tcgtttgatt ggaactggag
    26701 atttatttgt gccacttaaa ggtgcgcgtg atggccatga ctttattgaa acagcctttg
    26761 aaaatggtgc agcagtaacc ttgtctgaga aagaggtctc aaatcatcct tacattctag
    26821 tagatgatgt tttgacagcc tttcaatccc tagcatccta ctatcttgaa aaaacgactg
    26881 ttgatgtctt tgctgttaca ggttcaaatg gcaagacaac gactaaggat atgttggcgc
    26941 atttactgtc aacaagatac aagacctaca aaacacaagg caattacaat aatgagattg
    27001 gccttcctta cacagttctt catatgcctg aaggaacaga aaagttggtt ttggagatgg
    27061 gacaggatca cttgggagat attcatctct tgtctgaatt ggctcgtcca aaaacagcca
    27121 tcgtgacctt ggttggagaa gctcatttgg cctttttcaa agatcgttct gagattgcta
    27181 aaggaaaaat gcaaattgca gacggaatgg cttcaggttc cttgctttta gcgccggctg
    27241 accctatcgt agaggactat ttgccaactg ataaaaaggt ggttcgtttt ggtcaaggag
    27301 cagagctggg aattaccgac ttggttgagc gcaaagatag tctgaccttc aaggtcaatt
    27361 tcttagagca agcccttgat ttgccagtaa ctggcaagta caatgcgaca aatgctatga
    27421 ttgcatccta tgttgccttg caagaaggag tttcagagga gcaaattcgt ttggccttcc
    27481 aacatcttga attgacgcgt aaccgtaccg agtggaagaa agcagccaat ggagcagata
    27541 tcctgtcaga tgtttataat gccaatccaa ctgctatgaa actgatttta gagactttct
    27601 ctgccattcc agccaatgaa ggtggcaaga aaattgcagt gttggcggat atgaaggagc
    27661 ttggtgacca gtctgttcaa cttcataatc agatgatttt gagcctctcc ccagatgtgc
    27721 ttgatatcgt tattttctat ggagaagata ttgctcagtt ggctcaattg gccagtcaaa
    27781 tgtttccaat cggccacgtt tactacttca agaaaacaga agaccaggat caatttgaag
    27841 acctagtcaa gcaggttaag gaaagccttg gagcctatga ccaaatcttg ctaaaaggtt
    27901 ctaactctat gaatctagcc aaattggtag aacgtttaga aaatgaagcc aagtgatttt
    27961 gtcaagtatc tgcaaagaat gattgccctt acagatactg gcttaacctt tacaaaagat
    28021 ccttttgacc gtgagcgcta cgaggacttg cgaagtctgt tatctgaaat gttgaatcag
    28081 ggatcagacc tggatgcaga agaagtagca gaagtcttga aaccaacttc agcttatgcg
    28141 actcccttaa tggacgtccg tgcttggatt gttgaggatg agaagatttg tctggttagg
    28201 ggacaaggag aggatagttg ggctttgcca ggtggctttg gtgaagtcgg ctattctcca
    28261 actgaaaata ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga
    28321 ctgctagctg tttttgatac caatcgtttc caactacaga gtaaacaata tgcaaagttt
    28381 gtttttgaat gtaagtttct cgatggacaa ttccaagaaa atcaagaaat tgcagacctt
    28441 caattttttg ccattgatca actgccagcc ttatctgaaa aacgcattac caaggagcaa
    28501 atcgagattc tttggcaggt ttatcaaggt cagagggagc aatatcttga ctaagaagat
    28561 gattatcgta tttttaaatc catttttaac aactagcatg gtataataat atgcaggaaa
    28621 attttgaatt atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca
    28681 accgagccgc ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta
    28741 accttttata cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc
    28801 ttgcagactg ttcagttaat ccttctttat ggttggtact gggtcaatca tatgccactg
    28861 tcagaaagcc taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct
    28921 ggtcagtcca aatataaaca atactttgca ttattgggaa catttgggac attagcagcc
    28981 tttgtttatc cagtgccaga tgcttaccct tttccacata tcaccattct atcctttatc
    29041 tttggtcatt tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg
    29101 cgattgctgg atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt
    29161 gtggtcaatt tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg
    29221 gatcacggtc tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt
    29281 ttgactaaga aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag
    29341 gaagcttaac acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa
    29401 ataagaattt ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag
    29461 cacgattaaa ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg
    29521 gaataatacg aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag
    29581 gcttttttac aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga
    29641 gaaatggtga attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg
    29701 gaattattgt tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg
    29761 aagaaaaggc aggcatttcg attaaatcag tgaatgtcgg cttgcctggt aatcttttgc
    29821 aggtagaacc aactcagggg atgattccag taacatctga tactaaggaa attacggatc
    29881 aagatgttga aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag
    29941 tcattacctt tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac
    30001 gtggtatgat gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta
    30061 tcttgcacaa tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca
    30121 tttcaccact agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta
    30181 cagtgattga tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc
    30241 agttcacaca tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt
    30301 tgaaaacctc tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc
    30361 ctcttgcaag caaagaaacc ttccaagtag aggttattgg agaagtggaa gcagtcgaag
    30421 tgacggaagc ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa
    30481 tcaagcaaga attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg
    30541 gtgggaatgc cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg
    30601 tcaagcttta tgttccaaat caagttggta tccgtaatcc agcctttgcg catgtgatta
    30661 gtttatcaga atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa
    30721 aaggtgagaa tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag
    30781 ctcagtttgt acaatcaacg cctgttcaac cagctcctgc tccagaagta gagccggtgg
    30841 cgcctacaga accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag
    30901 atcgtttccg tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg
    30961 acattttcat ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt
    31021 ggaggtggtg gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt
    31081 atcgcagcaa acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag
    31141 ttgggaccta aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa
    31201 gccgctgaag aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc
    31261 atcactgctg gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc
    31321 gccaaagatt taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga
    31381 agtaagcgtg gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact
    31441 ctattgatta tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg
    31501 gaggctctta gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg
    31561 attaccaatc caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac
    31621 aaagggaatg ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg
    31681 gcacgtaagg caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt
    31741 atcgtcaacg ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa
    31801 attgtgaacc aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa
    31861 agtatgcgtg atgaaattcg tgtaacagtt gtcgcaacgg gtgttcgtca agaccgcgta
    31921 gaaaaggttg tggctccaca agctagaact gctactaact accgtgagac agtgaaacca
    31981 gctcattcac atggctttga tcgtcatttt gatatggcag aaacagttga attgccaaaa
    32041 caaaatccac gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc
    32101 cgtgaatcga ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc
    32161 ccaatttcac aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta
    32221 aatgaatgta aaagaaaata cagaacttgt ttttcgagaa gttgcagagg ctagtctgag
    32281 tgctcatcga gagagtggtt cggtctctgt cattgcagtt accaagtatg tagatgtacc
    32341 gacagcggaa gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa
    32401 gtttctggaa aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac
    32461 cttgcaaaga cgtaaggtga aagatatcat tcaatacgtt gattatttcc atgcattgga
    32521 ctcagtaaag ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct
    32581 tcaagtaaat atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga
    32641 aatcttgcca gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc
    32701 accttttgag gctagcagtg agcagttgaa agagattttc aaggcggccc aagatttaca
    32761 aagagaaatt caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat
    32821 gagtcgtgat tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc
    32881 attttttaag taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta
    32941 ttttacggag gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac
    33001 tccagtaaat tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggctgg
    33061 tacaaaagag aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag
    33121 tcagcgtgca acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc
    33181 aacagaaatt gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat
    33241 gacagaggtg caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc
    33301 tggaaatttg aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt
    33361 aaatgttgaa gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat
    33421 gaagcgaaat agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat
    33481 atttactccc tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa
    33541 tccagtttag gtcgttggat tgtagcgttg gtgaaaccag tgcttgctcc cttgcaacgc
    33601 ctgcctttac agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga
    33661 tttttaggag aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc
    33721 agcatttctc catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg
    33781 tagaagatag ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat
    33841 taaagatttt ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga
    33901 gtgagtatgt tcgagtttta ttatacccag attatttcca accagagttt tcagattttg
    33961 aaatatctct ccaggaaatt gtgtattcca ataaatttga acatttaacg catgctaaga
    34021 ttttagggac agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag
    34081 tagatgaaga acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg
    34141 gactaaagaa aattggtcgt atacctgttt cgctggagga acgtcctttc accgagaaaa
    34201 tagataagct agaacagtat cgagaactgg atttatctgt gtttagtttt cgattagatg
    34261 ttcttttatc aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga
    34321 aacttgtcca agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag
    34381 acttgattag tgtgagaaaa tttggccgct tgagattact tcaagataag ggacaaacga
    34441 aaaaagagaa gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc
    34501 aattacatca ttagaaataa aggacaagac ttttggaact cgattcagag gttttgatcc
    34561 agaagaagtc gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc
    34621 gaatcatgat aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga
    34681 aataaaagat tcattgagcc agtctgtatt gattgctcag gatacagctg agagagtgaa
    34741 acaggcggcg catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg
    34801 cttgttggaa gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc
    34861 taagaaagtc gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg
    34921 tctcaaatct acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat
    34981 tctccgtcca acagctactt atcttcaaac cagtgatgaa gcctttaaag aagtggttag
    35041 cgaagtactt ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg
    35101 tcagttctct caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga
    35161 attgtctgaa tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag
    35221 tcctcaagtt gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa
    35281 gtagctccag tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcaccg
    35341 ggatttgaag caccgcaaga atctgttaca attttataag aaatattctg agaacaatat
    35401 cttatcctta tattcccagc gagcaggaga tggtgtgagt cctgcattcc ctatcgataa
    35461 gattatcctc tcaaaaactc aagtctgaag ctagtaagat ttgacgttcc ccacgttacg
    35521 ggataagagg gagaaagact aaaacttttt ccgaataaag gtggtaccac gattttcgtc
    35581 ctttttggaa gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc
    35641 aaagacaccc ttaatcttgg gaaaactgaa ttcccaatgc gtgcaggcct tcctaccaaa
    35701 gagccagttt ggcaaaagga atgggaagat gcaaaacttt atcaacgtcg tcaagaattg
    35761 aaccaaggaa aacctcattt caccttgcat gatggccctc catacgctaa cggaaatatc
    35821 cacgttggac atgctatgaa caagatttca aaagatatca ttgttcgttc taagtctatg
    35881 tcaggatttt acgcaccatt tattcctggt tgggatactc atggtctgcc aatcgagcaa
    35941 gtattgtcaa aacaaggtgt caaacgtaaa gaaatggact tggttgagta cttgaaactt
    36001 tgccgtgagt acgctctttc tcaagtagat aaacaacgtg aagattttaa acgtttgggt
    36061 gtttctggtg actgggaaaa tccatatgtg accttgactc ctgactatga agcagctcaa
    36121 attcgtgtat ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt
    36181 tactggtcat ggtcatctga gtcagccctt gctgaagcag agattgaata ccatgatttg
    36241 gtttcaactt ccctttacta tgccaacaag gtaaaagatg gcaaaggagt tctagataca
    36301 gatacttata tcgttgtctg gacaacgact ccatttacca tcacagcttc tcgtggtttg
    36361 acggttggtg cagatattga ttacgttttg gttcaacctg ctggtgaagc tcgtaagttt
    36421 gtcgttgctg ctgaattatt gactagcttg tctgagaaat ttggctgggc tgatgttcaa
    36481 gttttggaaa cttaccgtgg ccaagaactc aaccacatcg taacagaaca cccatgggat
    36541 acagctgtag aagagttggt aattcttggt gaccacgtta cgactgactc tggtacaggt
    36601 attgttcata cagcccctgg ttttggtgag gacgattaca atgttggtat tgctaataat
    36661 cttgaagtcg cagtgactgt tgatgaacgt ggtatcatga tgaagaatgc tggtcctgaa
    36721 tttgaaggtc aattctatga aaaggtagtt ccaactgtta ttgaaaaact tggtaacctc
    36781 cttcttgccc aagaagaaat ctctcactca tatccatttg actggcgtac taagaaacca
    36841 atcatctggc gtgcagttcc acaatggttt gcctcagttt ctaaattccg tcaagaaatc
    36901 ttggacgaaa ttgaaaaagt gaaattccac tcagaatggg gtaaagtccg tctttacaat
    36961 atgatccgtg accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt
    37021 cctatcttct acgctgaaga tggtacagct atcatggtag ctgaaactat tgaacacgta
    37081 gctcaacttt ttgaagaaca tggttcaagc atttggtggg aacgtgatgc caaagacctc
    37141 ttgccagaag aatttactca tccaggttca ccaaacggcg agttcaaaaa agaaactgat
    37201 atcatggacg tttggtttga ctcaggttca tcatggaatg gagtggtggt aaaccgtcct
    37261 gaattgactt acccagccga cctttaccta gaaggttctg accaataccg tggttggttt
    37321 aactcatcac ttatcacatc tgttgccaac catggcgtag caccttacaa acaaatcttg
    37381 tcacaaggtt ttgcccttga tggtaaaggt gagaagatgt ctaaatctct tggaaatact
    37441 attgctccaa gcgatgttga aaaacaattc ggtgctgaaa tcttgcgtct ctgggtaaca
    37501 agtgttgact caagcaatga cgtgcgtatc tctatggata tcttgagcca agtttctgaa
    37561 acttaccgta agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac
    37621 ccagctcaag atacagtcgc ttacgatgag cttcgttcag ttgataagta catgacgatt
    37681 cgctttaacc agcttgtcaa gaccattcgt gatgcctatg cagactttga attcttgacg
    37741 atctacaagg ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt
    37801 gccaaagatg ttgtttacat tgaaggtgcc aaatcactgg aacgccgtca aatgcagact
    37861 gtcttctatg acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact
    37921 gcggaagaaa tttggtcata tcttgagttt gaagccgaag acttcgtcca attgtcagaa
    37981 ttaccagagg ctcaaacttc tgctaaccaa gaagaaatct tggatacatg ggcagccttc
    38041 atggacttcc gtggacaagc acaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc
    38101 ggtaaatcac ttgaagcaca cttgacagtt tatccaaatg aagtggtgaa aactctactc
    38161 gaagcagtaa acagcaatgt agctcaactt ttgatcgtgt cagacttgac catcgcagaa
    38221 ggaccagctc cggaagctgc ccttagcttc gaagatgtag ccttcacagt tgaacgtgct
    38281 gctggtgaag tatgtgaccg ttgccgtcgt attgacccaa caacagcaga acgcagctac
    38341 caggcagtta tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc
    38401 gcagaaggat ttgaagagaa ataagattga aaagtctagg caaaattcaa tttgagaaga
    38461 aaagacaact aattttatag tctattaaac gcattgtatc acgtttttga acacctgata
    38521 tgatgcgttt tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga
    38581 atcaaagaga aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg
    38641 ataagattgg taaatagtgt aatattttta caacaataaa tttatatagt tatttttggt
    38701 ttctgaaaag tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa
    38761 aatacttttt ttaaaagcaa atatgataca attttatttg aaaaaaataa aaaaggagat
    38821 tttattatga aattaaaaac acttgcttta attagtggta tcgtcgtctt gtgggaggaa
    38881 ttttacttct tattggtcct tttgtcttgt tgggaacagc ggtaaacaca gctgctacaa
    38941 ctcttaatgg aggagctact gcaggggctt tttcaggtgt tgccttactc ttgaatgcct
    39001 tgaagattgc aaatcttgtt cttggtatca ttgctattgt ttactataaa ggagataagc
    39061 gtgtaggtgc agctccgtct gtactaatga ttgtttctgg tggagttagt ctcattctat
    39121 tccgttctta ggatgggttg gggggattct tgctattatc ggaggatctc tattccttgc
    39181 aacattgaag aaattcaaat cagaagaata aaaggtattt tagcatgaaa agaacaaaaa
    39241 agtttatcgg tataggagta gctctattat ctctttctct tctagttgca tgtggaacat
    39301 aaagttcaaa gaatacttca acaagtaatg atgagaagac agtagcaaca tccaatagtt
    39361 caaaagaaac aatcactttc gatacaccgg ttgtaacaga cgatgcgatt gaatcaatac
    39421 gcacttatgc agattatata gatctttata aaaatatttt tgatgattat tttactaaag
    39481 ctgaggaagg tttcaaaggc acagttatgg aaaataatga ctcgtttact aaactaaaag
    39541 agtcaactca aaaattattc gatgcgcaga aaaaaaggtt aaataatgaa gatagaatag
    39601 aaacagccaa aaacaatgtg attgccaaac attgtcaaac agtcctttcc tttttggttt
    39661 tgactagctt ttttgtgaaa aattgtgtaa aatagaatag ataaacgagg ggaaacctcg
    39721 gaaaatttaa aggagaatcc atctaatggt aaaattggtt tttgctcgcc acggtgagtc
    39781 tgaatggaac aaagctaacc ttttcactgg ttgggctgat gttgatttgt ctgaaaaagg
    39841 tacacaacaa gcgattgacg ctggtaaatt gatcaaagaa gctggtatcg aatttgacca
    39901 agcttacact tcagtattga aacgtgctat caaaacaact aacttggctc ttgaagcttc
    39961 tgaccaattg tgggttccag ttgaaaaatc atggcgcttg aacgaacgtc actacggtgg
    40021 tttgactggt aaaaacaaag ctgaagctgc tgaacaattt ggtgatgagc aagttcacat
    40081 ctggcgtcgt tcatacgatg tattgcctcc aaatatggac cgtgatgatg agcactcagc
    40141 tcacacagac cgtcgttatg cttcacttga cgactcagta atcccagatg ctgaaaactt
    40201 gaaagtgact ttggaacgtg ctcttccatt ctgggaagat aaaatcgctc cagctcttaa
    40261 agatggtaaa aacgtattcg taggagctca cggtaactca atccgtgccc ttgtaaaaca
    40321 catcaaaggt ttgtcagatg acgagatcat ggacgtggaa atccctaact tcccaccatt
    40381 ggtattcgaa ttcgacgaaa aattgaacgt cgtttctgaa tactaccttg gaaaataaaa
    40441 aattgtaagt ctagaattga tttctaggct ttttatgtta gtatggaagt atgataagga
    40501 ataaaaaaca agattatgta ctggcctaca agcaaccagc ttcaaccact tacatgggtt
    40561 gggaagaaga agctttaccg ataggcaatg gttctttagg agcaaaagta tttggcctta
    40621 taggggctga acggattcaa tttaatgaaa aaagtctctg gtctggaggt ccacttcctg
    40681 atagttcaga ttatcagggt ggaaatcttc aggatcagta tgttttttag ctgagattcg
    40741 gcaggctttg gagaagagag attacaatct ggctaaggaa ctggctgagc agcacctaat
    40801 tgggccaaaa acgagtcaat atgggaccta tctgtctttt ggggatattc acattgagtt
    40861 cagccagcaa ggtacgactt tgtctcaggt gacggactat cagagacagc tgaatattag
    40921 taaggcactt gcgacgactt cttatgtcta taagggaacg cgatttgaac gtgaagcttt
    40981 tgcgagtttt ccagatgatc tcttggttca atgttttact aaggaagggt tggaaactct
    41041 agattttact atagaactat ccttgacctg tgatttggct tctaatggaa agtatgaaca
    41101 ggaaaagtct gattacaagg agtgtaagtt ggatattact gattctcata tcttgatgaa
    41161 gggaagagtt aaggataatg atctgcggtt tgctagttat ctagcttggg aaacggatgg
    41221 agatattaga gtttggtcat atagggttca gatatcagga gccagttatg ccaatctctt
    41281 cttggccgct aagacggatt ttgcccaaaa tcctgctagc aattatcgca agaaactaga
    41341 tttagagcaa caggtgagag acttggtgga cacagctaaa gaaaagggct atacccaatt
    41401 gaaatcaagg catatcgagg actaccaagc cttattccag cgtgttcaat tggatttgga
    41461 agctgatgtt gacgcatcca ctacagatga tttgttaaaa aattataagc cacaagaagg
    41521 gcaggctttg gaggagctgt tcttccagta tggacggtat ttattgatta gttcgtccag
    41581 agactgccca gatgctctac cagctaacct acagggagtc tggaatgcgg tcgacaatcc
    41641 tccttggaat tcggactatc acttaaatgt caatctgcag atgaattatt ggccagccta
    41701 tgttaccaat ctcctagagg cggtctttcc ggtcatcaac tatgtagatg atttgcgtgt
    41761 ctatggtcgt ctagcggctg taaagtatgc aggaatcgtc tctcaaaaag gtgaggaaaa
    41821 tggttggttg gttcatactc aagcgactcc ctttggttgg acggcacctg gttgggatta
    41881 ctattggggt tggtcaccag ctgccaatgc gtggatgatg caaaccgttt atgaagccta
    41941 ttcattttat agggaccaag actatctcag agagaaaatt tatcccatgt tgagggaaac
    42001 ggttcgtttt tggaatgcct ttttacataa ggatcagcag gcgcagcgtt gggtgtcttc
    42061 tccgtcttat tccccagaac atgggccgat ttcgattggc aatacttatg accaatctct
    42121 aatttggcag ttatttcatg attttattca ggctgctcag gaattgggac tggatgagga
    42181 cttgttgact gaggttaagg agaagtctga tttactaaat cctttgcaaa tcactcaatc
    42241 tggtcgaatc agggagtggt atgaggagga agagcagtat tttcaaaatg agaaagtgga
    42301 ggcccagcat cggcacgctt cccatctagt gggactctat cctggcaatc tctttagcta
    42361 caagggacaa gagtatattg aagcggcgcg tgctagcctc aatgatcgtg gagatggcgg
    42421 cacaggctgg tccaaggcta ataagatcaa tctctgggcg cgtttgggag atggcaatcg
    42481 agcccataaa ttattggcag agcagttaaa gacatccacc ttgccaaatc tttggtgtag
    42541 ccatcctcct tttcagatag atggtaattt tggtgctact agtggcatgg cagaaatgtt
    42601 actccagtct catgcagctt atctggtacc tctagctgcc ctacctgatg cttggtcaac
    42661 aggttctgtt tcaggcttaa tggcacgtgg acattttgaa gtgagcatga gctgggaaga
    42721 taaaaaactc ttacagttga ccattttatc aaggagtgga ggagatttgc gagtttctta
    42781 tccagatatt gagaagagtg tgattaaaat gaatcaagaa aaaataaaag cgaaatgcat
    42841 ggggaaagat tgtatttcgg tggcaacagc agaaggtgat cttgttcaat tttattttta
    42901 agaagatgtt ataaggcagt aatttgaaac tgccttttaa taaggattta agaatataag
    42961 cagttttcaa ctagttgaaa aagcgttata atgataatag gaagtaatac tcaatgaaaa
    43021 tcaaagagca caaacaagga agctagccgc aggttgctca aaacagtgtt ttgaggttgc
    43081 agatggaagc tgacgtggtt tgaagagaga ttttcgagga gtataatttg tttgatagag
    43141 ggtgggtctg atggtttata ttgagatgaa acactgttac aagcgttatc aggttgggga
    43201 cacggagatt gtggccaatc gtgatgtgaa ttttgagatt gaaaaggggg agctggttat
    43261 tatccttggt gcttcaggtg caggcaagtc aacagtgctt aaccttcttg ggggaatgga
    43321 taccaatgat gaaggggaaa tctggattga tggtgttaat attgcggatt atagttccca
    43381 ccagcgcacc aattaccgta gaaatgatgt ggggtttgtt tttcagtttt ataatctagt
    43441 ttctaatctg acagctaagg aaaatgtgga actggcttct gaaattgtga cagatgtctt
    43501 gaatcctgat caggtcttga cagatgtagg tctggctcat cgtctaaata actttccagc
    43561 ccagctttct ggaggggagc aacagcgagt ctccattgca cgcgcggtag ccaaaaatcc
    43621 taaaattctt ctttgtgatg aacctactgg agccttggat tatcagacgg gcaagcaggt
    43681 tttgaaaatt ctccaagata tgtctcgtca aaagggagcg acggtgatca tcgtgactca
    43741 taatggagct ttggcgccca ttgctgatcg cgtgattcat atgcacgatg ccagtgtcaa
    43801 ggatgtggtg ctcaaccagc atcctcagga tattgacagt ttggagtact agtatgatca
    43861 agcgaaaaac ttattggaag gacttaattc agtccttcac aggctccaag gggcgttttt
    43921 tatccatctt gatcctgatg atgttgggct ctctagcctt agtaggcctc aaagtaacca
    43981 gtcccaacat ggaggcgaca gctaatgctt atttaacaac tgctcaaacc ttggatttgg
    44041 cagtcatgtc taactatggc ttggatcaag cagaccaaga agaactaaaa cagacggagg
    44101 gcgcagaggt cgagtttggc tatttgacag atgtgactat ggataatggg caggatgcca
    44161 ttcggctgta ctccaaacca gagcgaattt caacctttca gctaagaaag ggacgacttc
    44221 ctcagtcaga caaggaaatc gctttggcca ctcatttgca aggccaatgc agcgtgggac
    44281 aggagattag ttttaaagaa aaagaagagg gtcattcctc tttaaaagac catacttata
    44341 ccattactgg ttttgtggat tcggctgaaa tcctctccca gcgagatatg ggctacgcag
    44401 gaagtggaag tgggactctg acagcctatg gggtgatttt acctagtcag tttgatcaga
    44461 aagtctacaa tatagctcgt ttgaaatatc aagatttagc aggtttaaat gccttttcat
    44521 cagcttatga agaaaaatcc aagcaacatc aggaagacct tgaacaaact ttatcagata
    44581 atggcaaggt acgtctgcaa cttttgaaaa aagaaggaca agagtctcta gacaaggggc
    44641 aagagaccct tgacaaggct cagactaatt tgcaggaagg caagcgtcgt ttagcagctg
    44701 ctcaagctcg tatacaggct caagaaagtc aactagcctt gtttcctcaa gttcagagag
    44761 agcaggctag tgctcaactt acccaagcca agcaggaatt gggcaaggaa gaagacaaac
    44821 taaagcaagc tgaacaaaat ctagcccaag aaaaggaaaa attagaaaaa catcagcaag
    44881 tcttggacga tttggcggag ccaaggtatc aggtctataa tcgtcagacc atgccaggtg
    44941 gtcagggcta tcttatgtat agcaatgctt catccagtat tcgagcagtg ggcaatatct
    45001 ttcctgtggt actttatgcc gtagcagcca tggtgacctt tacgaccatg actcgctttg
    45061 tagacgaaga gcgaactcat gcagggattt ttaaggcctt gggttaccgt agtaaggata
    45121 ttatcgccaa gtttctcctt tatggactag tagctgggac tgtcggaacg gctctaggta
    45181 gtatacttgg tcattatttg ctagccagtg taatttcaag tgtcattaca aaaggcatgg
    45241 tggtgggaga aacccagatt cagttctatt ggacctatag cttactagct cttgtcttga
    45301 gctggttggc gagtgtgtta ccagcctatc tggtggcttg gagggaactt catgccgaag
    45361 cagcccagct tctacttcct aaacctcctg tcaaaggagc taaaatctta ttggagcgta
    45421 tcggttttat ctggcgtcgt ctcagtttta ctcataaggt aacagcccgc aacatctttc
    45481 gttataagca gagaatgttg atgacaatct ttggtgtggc aggttctgta gctctgctct
    45541 ttgcaggttt gggaatccaa tcttctgtag caggagttcc gtctaaacag tttcaacaaa
    45601 tccaacagta tcagatgctt gtctctgaaa atcctagtgc gaccaatcag gacaaggtag
    45661 agctagcaga agtgttgaaa gggcaggaga tactagccta ccagaaaatc tattctaaaa
    45721 cgctagacaa ggatttcaag ggcagggctg gtcttcaaaa cattactctt atgatgatag
    45781 agaaggaaga tttgactccc tttatccatc ttcaacatca tcagcaggag ctgacattaa
    45841 aagatggcat cgttattaca gctaaactcg cccagctggc aggtgtcaag gttgggcaga
    45901 ctttagaaat tgaaggtaag gaactaaagg tcgctgctat tactgagaac tacgttggtc
    45961 actttattta tatgagtcag gctagctatg agcaacttta cggacagcta ccccaagcca
    46021 acacttatct ggtctcatta agggatacca gtgcaactag tatcgaaagt caggcgggct
    46081 tgcttatgaa tcaatctgcg gtgtccagtg ttgtccaaaa tgcttcagcc attcgactct
    46141 tcgactctat cgctagctca ctcaatcaga ccatgaccat cttggtcatc gtatcggttc
    46201 tattagctat tgtcatcctt tacaatctga ccaatatcaa cgtagctgag agaatccgtg
    46261 aactctccac tatcaaggtt ctcggttttc ataataatga agtcaccctc tacatttacc
    46321 gtgagacgat tgtgctgtcc cttgtgggaa tcgtacttgg tctggtagct ggtttctatt
    46381 tacaccaatt tttgattcaa atgatttcgc ctgcgactat tctcttttat ccgcaggtag
    46441 gctgggaagt ctatgtaatc ccagtggcag cagtaagcat cattttgacc ttgcttggtt
    46501 tcttcgtcaa ttattatctg agaaaggttg acatgttaga agccctgaaa tctgtagagt
    46561 aaggtagtta tttttagctg attgaacttc tatttactaa tattcaaaaa tcctccgttt
    46621 caaagagcag ggaactcttt gtgacagagg attttttcta tagggcttta gcagctgcaa
    46681 ttgcggcttc gaagtttggc tcagaattga tattatccac gtattcaacg tagcgaatcg
    46741 tattgtcagt atcgaggaca aagactgcgc gtgctaatag gtgccattcg ttgatcaaga
    46801 gggcataatc gcgtccgaaa gaatggtcaa agtagtctga aagcataatg gcattgtcaa
    46861 ggccttcagc accgcaccaa cgtttttgag caaaaggtag gtccattgaa acagtcaata
    46921 cgaccgtgtt gtccagtcca gccaattctt cattaaaacg acgtgtttga gttgagcaga
    46981 tgcctgtatc gatagaagga acgacactca agactttttt cttgccatca aaatcagcca
    47041 gagatttttt agaaagatct gttgtagtaa gagaaaaatc aagcgccttg tcgccgactt
    47101 gtagttgttt acctgtaaag ctcacaggat ttccgagaaa agttaccata ggatactcca
    47161 atcttttttc ttccattgta tctgaaacag tcagaatttt ccaatgattt gaccggaaat
    47221 gtgtgcatag aaaaaacgcc agctcacatg agaatgacgt ttttcagagg cttattttgc
    47281 caatccttca gcaatcttgt caaggttgta tttcatcatg ctgtagtagc tgtcgccttc
    47341 tttaccttgt tctgcgatag agtcagtaaa gatttgtgcg tagattggga tgtttgtgtc
    47401 ttgagaaaca gttttcattg gacggtcatc cacacttgat tctacaaaga gtgatggaac
    47461 ttttgtttgg cgaagttttt caaccaaggt cttgatttgt tcaggagttc cttcttcttc
    47521 agtattgatt tcccagatgt aggcacttgg gacaccatag gctttagaga agtatttgaa
    47581 tgctccttcg ctggttacaa tgagtttctt ttcagcaggg atcttattaa atttatcctt
    47641 actttcttta tcaagtttgt ctaacttatc agtatattct ttgagatttt tttcatagaa
    47701 ttctttattg ttagggtctt tggcgctcaa ttgtttggcg atatttttag caaaaataat
    47761 accgttttca aggttaagcc aagcgtgtgg gtcttctttt cctttttcat tttgaccttc
    47821 aaggtagata acatcaacgc cgtcgctgac tgcgaagtag tctttgtttt cagttttctt
    47881 ggcattttct accaattttg taaaccaagc attgccacct gtttcaaggt tgataccgtt
    47941 atagaaaatc aaatcagcct cagaagtttt cttaacgtct tcaggaagtg gttcgtattc
    48001 gtgtgggtct tgcccaatcg gaacgatact atgaaggtca attttgtcac cagcaatatt
    48061 tttagtaata tcagcgatga ttgagtttgt agcaacaact tttagttttt gaccagaagt
    48121 tgtatctttt tttccgctag cacatgctac aagaatgatt gcagaaagaa agagaacgag
    48181 taatgtacct aattttttca ttagatcctc caatttatta gggctttgcc ccttatttta
    48241 acaaatgttt atttttcagt ttcaaatatc gttgtttggg agcgataaag aagctaatga
    48301 gaaagaaact agcagctgta agcacgatac tagaacctgc cgcaacatta aaactatagc
    48361 caataaagag tcccaaaact gaagcagtag ctccgaaggt tgaggaaagg aaaatcatgc
    48421 ttttcagact attagcatac agataagcag ttgcagctgg ggtaatcagc atggctacaa
    48481 tcaggatagt tccgacactt tgcatggctg tcacagacac gagagtcagg agtaccatga
    48541 gaaggtagtg atagaaattg acaggcattc ccatggcttt agccaagagt tcatcaaagg
    48601 aagttatcaa gagttgcttg aagaaaatcc agattaacaa gaggatggct gcccccacac
    48661 ccatagtaat aaacatatcc gtatcttgga cggccaggat attaccaaaa aggatatgga
    48721 aaaggtcagt tgaactttta gcgacaccaa tcaagatgat accgagggct aagaaagaag
    48781 aaaaggtaat gccgatggcg gtatcgcttt tgataatcga gtttcctttg atgtaggtaa
    48841 tgatgatggc agctagcaat ccaaagacaa tggctccgat aaagaagtca aggcccaaga
    48901 tgaaggagag ggctacacct ggtaagacag catgtgaaat ggcatctccc atgagtgaca
    48961 tcccgcgtag aataatgaaa catcccacgg ctccagctac aatcccgacg acaatagctg
    49021 ttatcaaggc attttgtagg aaatggaatt tttgcaatcc atcgataaat tctgcaatca
    49081 taggtcacct ccattgaaaa agagttgatt accgtaagct tcttttagat tggtttcggt
    49141 aaaagtttct tttgttggac caaaggcaat cacttctcga ttgacaagta agacttgatc
    49201 gaagtagtgg ggaatcttgc tgaggtcgtg gtgaacgatg agaaccgtct tcccagcttt
    49261 tttcaaatct ctcagcgtat tcatgatgat ttcctcactg acagagtcaa tcccagcaaa
    49321 gggttcatcc aagaggatat agtcggcttc ctgcaccaaa catctggcaa tcaagacccg
    49381 ctggaattga cctccagaca gttgactaat ttgacgttca gcgtagtcag ctaggccgac
    49441 gatttcaagg gcctcttgca ctttcttcca atgtttagcc tttaaacttc gaaagagagg
    49501 aatagaggga aatagtccta acgagacgca ttccttgacc ttgatgggaa agttgtagtc
    49561 gatattgatt ttttgttcga cataggcaat tcggtgtaag gattttttaa cttccttgtc
    49621 atcgagaaat gcctgacctt gatgtgggat aattcccaac atacctttta atagtgttga
    49681 tttcccagcg ccgtttggac caatgatgcc ggtaattgtt ggtccatgga gcactagtga
    49741 aatatcctta agtgccaacg tttctttgta ggagacactg aggttttcga tacgtatcat
    49801 aaacttatat tcctcctgtc tcttaatata cattaaaaaa aaaattaagt caagttaatt
    49861 tttgaaaaaa ttaaaataat aactgaaaaa tagattctaa aaataacttt caggataaat
    49921 ttctaaatta taaaacgcat agtatcaagt gtaaaaaact tggaattatg cgttttatca
    49981 tggaaagatt ttttataata gctaaaaaat aatagttaaa tggttattaa ttgcattccc
    50041 tagtgatttt tgttaagata aatgcaaata caaatgaaag cgagaacaag atgacacgtt
    50101 atcaagatga tttttatgat gctatcaatg gagaatggca acagacagct gaaatcccag
    50161 cagataagtc tcaaactgga ggttttgttg atttagacca ggaaattgaa gacctgatgc
    50221 tggcgacaac agacaagtgg ttagcaggtg aagaagtgcc tgaggatgct atcttggaaa
    50281 actttgtcaa ataccaccgc ctagttcgtg attttgacaa gagagaagct gacggtatca
    50341 cacctgtctt accactcctt aaagaattcc aagaattgga aacttttgcg gattttacag
    50401 ctaaactagc agagtttgag cttgcaggaa aaccaaactt ccttcctttt ggtgtatcgc
    50461 cagactttat ggatgctaga atcaatgttc tatgggctag cgctccaagc acaatcttgc
    50521 cagatacgac ctactatgca gaagaacatc ctcagcgcga agagctcttg actctttgga
    50581 aagaaagcag cgcaaatctc ctcaaggctt atgatttctc tgatgaagaa attgaagact
    50641 tgctagaaaa aagacttgaa ttggaccgcc gagttgcggc agtggtgctc tctaatgaag
    50701 aaagttcaga atatgctaaa ctctatcatc catattctta cgaagatttt aagaaattcg
    50761 cgcctgccct acctttggat gacttcttca aagcagttat tgggcaatta ccagacaagg
    50821 ttattgtaga cgaggaacgt ttctggcaag cagcagagca attctacagt gaggaagcct
    50881 ggtctctcct taaagcaacc ttgattttga gtgttgtcaa tctttcaacc agctatttaa
    50941 cagaggatat ccgtgttttg tctggtgcct acagccgtgc cctttctgga gttccagagg
    51001 caaaagataa ggtcaaagca gcttatcatc tagcacaaga acctttcaag caagccctgg
    51061 gtctttggta cgcccgtgag aagttctctc cagaagccaa ggcggatgtg gagaaaaaag
    51121 tggcaaccat gattgatgtc tataaggagc gtctgcttaa gaatgactgg ctcactccag
    51181 aaacctgtaa acaggctatc gtgaagctca atgtgatcaa accttatatt ggctatccag
    51241 aagaattgcc tgcacgttac aaggataagg tagtgaatga aactgccagt ctttttgaga
    51301 atgctctagc ctttgcgcgt gtggaaatca agcacagttg gagtaagtgg aaccagcctg
    51361 tagactataa ggaatggggc atgcctgctc atatggtcaa tgcctactac aatcctcaga
    51421 agaacctgat tgtctttcca gcggccattt tacaggcgcc tttctatgac ttgcatcagt
    51481 catcttctgc taactacggt ggtattgggg cagtgattgc ccatgaaatt tcccacgcct
    51541 ttgatactaa cggggcttcc tttgacgaaa atggtagcct caaggattgg tggacagaga
    51601 gcgactatgc tgccttcaag gagaaaacac aaaaagtcat tgaccaattt gatggacagg
    51661 attcttatgg agcaaccatt aacggtaaat tgactgtatc agaaaacgtg gctgacttgg
    51721 gaggaatcgc agcagcgctt gaagcagcta agagagaagc agacttctca gcagaagagt
    51781 tcttctacaa cttcggtcgc atctggcgca tgaaaggtcg accagaattt atgaaacttt
    51841 tggctagcgt cgatgtgcac gcaccagcca aactccgtgt caatgtgcaa gtaccaaact
    51901 tcgacgattt ctttacaacc tatgatgtca aagaaggaga cggaatgtgg cgttcaccag
    51961 aggagcgcgt gattatttgg taatacaaaa aatctagtca tcagaaaaaa ggcatccaat
    52021 cacgtgtgaa aaccttgata ggatgccttt tgtaatagaa agatttgctg gatagtttac
    52081 ttaaatttcg attgtcatca tcttgctaga aaaagggatt gaaggccttt tcgtgagcga
    52141 tagtagtagc tggaccatgt cctggataga catcgtagtt tggtagggtg aagagttggg
    52201 tctggatact atgaaggagt tgctccatgc taccagtcgg aaggtcggtc cgtccgatag
    52261 tttcgcggaa tagagcatct cccgtcaaga ctaggtgagc atcaggaaag actagggaaa
    52321 caccaccgat agagtgccct ggggtcggta gaaccttaaa acgaaattcc tctagttggt
    52381 attcttcgtg aaagacaaag gtgtgttctg caggttttgt gaccacatct gccatatcat
    52441 cgtggcgagg gagaccggag agattatcga caggagtgta gagccagctg gcttcgctct
    52501 ctgcgatata gacaggagga ttgccaaacg tctcgcgaac caagtccaga ctcatgatat
    52561 ggtcataatg ggcgtgggtc aagagaatag cacagatcgg tttgttgatc ttctcgattg
    52621 tctgacgaat ggcttcccaa tgactaccag gatcgacgac gatgaggtgc ttttcgcctt
    52681 ctagataata ggtattttca taggcaacag gattcacggt tttatggatt ttcatactag
    52741 ctccaatctc aaagaatgta ctaatactct tcgaaaatct cttcaaaccg cgtcaacttt
    52801 atctgcaacc tcaaagcagt gctttgaaca gcctgcggct agctttctag tttgctcttt
    52861 gattttcatt gagtataaat taagtatagc acagttaggg agaataggta aggatttaaa
    52921 atgaacttaa aaaccagcat gactagatga agacaggctg gttatcaatt tatcaatatt
    52981 ggaaaggtgt caattgccct tcataggttg cataaactcc gtcattagct tgtttgatag
    53041 acgtgatgtt tagagtgcta ccgtagttgg cttatcattt gtcgctatat tcactataag
    53101 ttatcctact gggcaggttc tggtcgttag catagtattg aacgagtttt ttatagcttt
    53161 gctggctgaa taggaacagg cagcaaactc ctaacattag gagagcaaag atagaaatag
    53221 cagttttttt cataggtatt ctccttataa actaaaggat agaagaaagt atcttgagga
    53281 tttttatact cttcaaaaat ctcttcaaac cgcgtcaaca atctcttcaa accgcgtcaa
    53341 cgtcgccttg ccgtatatat gtgactgact ttgtcagtct tatctacaac ctcaaagcag
    53401 tgctttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat tgagtattaa
    53461 ttccaaaatc cagtcaaggt accagtgtat gtgatacgag ttccaccgtt tatctttcgt
    53521 atcttcaatg gaattgggga aatcagaaag tctttgggtt acaatatggt ttccgttctt
    53581 ctatctctcc ttctatcacc taagtttaaa atctaacttc gtagtatatt atgggccaat
    53641 aattcagaat tatcaagcaa ttttgaatta tttttttctt attctgttcc aatctagttt
    53701 tcatattctt aaaaaagtga taaaatggta ggaagaattg gagagtagag atgccgaaag
    53761 aagtgaattt aacaggcgaa gaagttgtcg ctttaaccaa agaatattta acggaagagg
    53821 atgttcattt tgtccataag gccttggtct atgctgttga atgccacagt ggtcaatatc
    53881 gcaaatcagg cgagccttat atcattcacc ctatccaagt ggcaggtatt ttagctaagc
    53941 taaagctgga tgctgtaaca gtagcttgtg gattcttgca tgatgtggtg gaagatacag
    54001 atgcgacctt ggacgatttg gaaagagagt ttggtcctga tgtgcgggtg attgttgacg
    54061 gagttaccaa gcttggcaag gtcgagtaca aatcgatcga ggagcaatta gcggaaaatc
    54121 atcgcaagat gctcatggcc atgtctgagg acatccgcgt tattttggtc aaactgtctg
    54181 accgcttgca caatatgcgg accctgaaac atcttcgaaa agacaagcag gagcgtattt
    54241 ccaaagaaac catggaaatc tatgccccac ttgcccatcg tttggggatt tccagtgtca
    54301 aatgggaatt agaagacttg tctttccgtt atctcaatcc aacggagttt tacaagatta
    54361 cccatatgat gaaggaaaag cgcagggagc gtgaggcctt ggtggatgag gtagtcacaa
    54421 aattagagga gtatacgaca gaacgtcact tgaaagggaa gatttatggt cgtcccaagc
    54481 atatttactc aattttccgc aaaatgcagg acaagagaaa acggtttgag gaaatctatg
    54541 atctgattgc tattcgttgt attttagata cccaaagtga tgtttatgcc atgcttggtt
    54601 acgtgcatga attttggaaa ccgatgccag gtcgcttcaa agactatatt gccaaccgca
    54661 aggccaatgg ttatcagtct atccatacga ctgtttatgg accaaaaggg ccgattgaat
    54721 tccagattcg aaccaaggaa atgcacgagg tggctgagta cggggttgcg gctcactggg
    54781 cttataagaa aggtataaag gggcaagtta acagcaagga atcagctatt ggaatgaact
    54841 ggatcaagga gatgatggag ctccaagacc aggctgatga tgctaaggaa tttgtggact
    54901 ctgttaagga aaactatttg gctgaggaga tttacgtttt taccccagat ggagctgtcc
    54961 gttcccttcc caaagattca ggaccgattg attttgccta cgaaatccat accaaggtcg
    55021 gtgaaaaagc aactggtgcc aaggtcaatg gccgcatggt tccactgaca accaagttaa
    55081 agacagggga tcaggttgaa attatcgcca acccgaactc ctttggacct agccgtgact
    55141 ggctcaatat ggtcaagact agcaaggcgc gcaataagat tcgccagttc tttaaaaacc
    55201 aagataagga attgtctgtc aacaagggtc gtgagatgct gatggctcag ttccaagaaa
    55261 atggctatgt ggcaaataaa tttatggaca agcgccacat ggatcaagtt ctgcaaaaga
    55321 ccagttacaa gacagaagac tccctctttg cggccattgg ttttggggaa atcggtgcga
    55381 ttaccgtctt taatcgtctg actgaaaagg aacgccgtga ggaagagcgt gccaaggcca
    55441 aggctgaggc agaggagctt gtcaaaggtg gcgaggtcaa ggttgaaaat aaagaaactc
    55501 tcaaggtcaa gcatgagggg ggagtggtta ttgaaggtgc ttctggtctc ctagtgcgga
    55561 ttgctaagtg ttgtaacccc gtgcctggtg acgatattgt tggctacatt accaagggtc
    55621 gtggtgtggc tattcaccgt gtggactgta tgaacctgcg tgcccaagaa aactacgagc
    55681 aacgtctcct tgatgtggaa tgggaagacc agtactctag ctcaaataag gagtatatgg
    55741 cccatatcga tatctacggt ctcaaccgta caggactgtt gaacgatgta ctgcaagttc
    55801 tttcaaatac aaccaagaat atttcaacgg tcaatgccca accaaccaag gatatgaagt
    55861 ttgctaatat ccatgtgtcc ttcggtattg ccaacctctc tacactgacc acggttgtcg
    55921 ataaaattaa gagtgtgcca gaagtttact ctgtcaaacg gaccaacggc tagttgtcct
    55981 agctcttact agaaaggcta ttatgaaaat cattatccaa cgggttaaaa aagcccaagt
    56041 gagtatagaa ggccagattc agggaaaaat caatcaggga cttttattgc tggttggtgt
    56101 tggaccagag gaccaagagg aagatttgga ctatgctgtg agaaaactgg tcaatatgcg
    56161 gattttttca gacgcagaag gcaagatgaa cctgtctgtc aaagatattg aaggagaaat
    56221 cctctctatt tctcagttta ccctctttgc ggatactaag aaaggcaatc gtccagcctt
    56281 tacaggggca gctaaacctg atatggcatc agacttctat gatgctttca atcaaaaatt
    56341 agcgcaagaa gtgcccgttc agacaggcat ctttggagca gatatgcagg ttgaactggt
    56401 taataacgga cctgttacta ttatcctaga tactaaaaag agataagaaa gaccaagccc
    56461 agtcggcttg gtctttctca tcgatcataa aatactccaa aaagaaatcg gttcttgata
    56521 tgcttggggg aagtctcttt tcaggctttg gcagatgcga taggaaggga tgagatatcc
    56581 taggatgagg agagttccct gaaggaaaag tggaatatca cttaaagaca ccaaggagag
    56641 aatcatcagg ctatcccata ggagaatttg taaagcaaaa cgccagaatc tcggtctaat
    56701 ctgggaatag agttaactaa agtggtcaca aagttggttt gaaagatagg tcaatagcac
    56761 aggatgaaag aaaatgagcc aaccactata aatcaaaatc cagtcccaag taagcccccc
    56821 ttttaaatgt caaaaatgcc agcatgattc catcaatgac aaggagttga atggttttga
    56881 tgaagatgat ttttttcatg ctaaaacctc cttttttcat ctgttagtga cgtaatgctt
    56941 tatataatta ttatacagta ttcagtcggg atatgaaaac gtttactatc gtttttgata
    57001 taaaaaatag ataagaaaac cctgaaaata aaactttcag ggttggtagg ggacttgaga
    57061 aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac ttgtaaatcc
    57121 tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt gacttggagc
    57181 tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa actatcgtgc
    57241 acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag gttattgatt
    57301 tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt tttagggaaa
    57361 cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc caagacctca
    57421 gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa aacttcaatc
    57481 aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt cagtagatag
    57541 ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat catttcagtt
    57601 acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat cttatgcagg
    57661 tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt cattcgtttc
    57721 ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct agctgtgact
    57781 ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg aaaatagctc
    57841 ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca gatgctcagc
    57901 agctaggagt ggatgaatac tggcttttgg gagatattct catgccaggg acaggacgta
    57961 gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg ggaaactggg
    58021 aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgccct agtcaacgct
    58081 atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa attgaagtgc
    58141 tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg ggaattagcc
    58201 atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa caagaggagt
    58261 ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat attcaccagc
    58321 agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg attggccaac
    58381 ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg attttggagt
    58441 ttgatgacaa gggcctggta gatatggact tccgacgggt agattacgat gtggcagctg
    58501 aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat gaaagtctgg
    58561 tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct cagaaagagg
    58621 gttgcgatcg ggagttagac gactggttga aaagtggtaa cgattgacat tacaactaaa
    58681 aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa aaggagaaga
    58741 ggatgcaaat tccaagtaga tttaccattg caactcatat gctgataatc attgccctcg
    58801 aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgttggg gtcaatcctg
    58861 tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca gtagcgcgtg
    58921 gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta gatgtttatc
    58981 aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac aatccgaatc
    59041 caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg gagagaattc
    59101 agttgactat ggaggcagaa cttggtcaga ccagtctaga aaaagtcgtg gccgatgcag
    59161 agagtcagat gaaggattaa gagggataaa tgccctcttt ttttctttgg ataattatga
    59221 taaaatgtag ctattaaagg agtaagaaat gtatctcgtt atagaaattg tattagcctt
    59281 tatagtgtca ttttggaagg ataatagaag tttgtggaat ccagtattat ttttattatc
    59341 cctcatttca agttattttt atctatccta ccttttttat aaaaatggat acgagaatgt
    59401 tcagttagct ttttatgtat ttgcctttgt cttacttcct tttttgcttt ttctaagtgg
    59461 catcttttta atctataatg gggtcatttt gttgaaacga gagggacgtt ccaagcccca
    59521 ttatctctca atgctctttg atttttattg actattagat tctatttaaa aagacttaga
    59581 atgcacatga aagtatgtat tctaggtctt ttgttttgta tacatttaat tttcaagagt
    59641 attatctatt tttccatgca tggtaacgag tatcaatcaa taactgggta aggcgaccca
    59701 aggtttctct ttcttctgga gtgagggatt gagcttggac aaagagatga tgaatgtatt
    59761 caagcgcctt taaggaagcc aagtcattga tagagctaat accagcatca agaatagtgc
    59821 caaagaagag gtcgaagtag agctgaagtt cttcgtcagg gactgtggtc acccattctt
    59881 taaaggttgt gtctacttgc cggctatcac tgttggtctt atccagttga acgaagtgct
    59941 tgtcctcaat ctgccaacta aaggtatcgt gctgggcgat gccacccagg gcagtactct
    60001 gaacgatgat ttggtgagca ggaatttcca gcatcatacc gataatggaa ccttgtggaa
    60061 tgaatatctt gcttctatcc attatccttt gataacccgc agtctgtgtc aattcttgat
    60121 ggagaccagg tgcatcaaat gtataaactg ctgtgatctg attttgcaaa ctttgctcaa
    60181 tttggctagc agcatagata gcgagatttc ctcccttgga atgcccagcc agaataacct
    60241 tttgcttagg atgatgggca aaaaagttct ttaaatagcg aagggcgtgc ttttgagcag
    60301 gaatttcctt catataggtc aggtggaaat cttccttcca gccaatgata ctgtcatctg
    60361 tcccacgaaa gacaatcaga taggtatcga ggctgacacg ataagtcata gccgcaaatt
    60421 gcttttgcag ttcagggtcg atgtcgttga taaaatggga gagtttgcaa tttttgaagc
    60481 gcttgtgttg agccaattca tctaataatt gaaggcgatt tttgctagta agcatggtgg
    60541 gctctcttgg aacctgaggt gctagatcta aaagacgttg aggaagtgtg gagaccagat
    60601 tatcaaagga gaggtaggtg atttctatta aggttagaat gtctaactca ttcaagggaa
    60661 ggtcgtaata agaatcatat gcgacatctt tcagatagtc aaaaatattg gccataagag
    60721 ctcctttctt tttatttatc ttagcaaatt tccctcaaat tagctagtag catagcctgt
    60781 ttgtactggc taaaaacagg ctatttcaaa ttcagtttca gaccatctag catggaaaaa
    60841 tctgttataa taatggaaaa ggagaagcgc atgcacaaga ttttattaat agaagatgat
    60901 caggtcattc gtcaacagat tgggaaaatg ctctctgaat ggggatttga agtggtcctg
    60961 gtagaagact ttatggaagt tttgagtcta tttgttcagt cggaacctca tctggtcctc
    61021 atggatattg gtttgccctt gtttaatggt tatcactggt gtcaggaaat ccgcaagatt
    61081 tccaaggtac ctatcatgtt tctttcttcg agagaccagg ctatggatat tgtcatggca
    61141 atcaatatgg gggcggatga ctttgtgacc aagccttttg accagcaggt tcttttagct
    61201 aaggttcagg gcttgttgcg tcgttcctat gagtttgggc gtgatgagag tttgctggaa
    61261 tatgctggtg ttatcctcaa taccaaatcc atggatttac attatcaagg gcaagtcttg
    61321 aatttgacca agaatgaatt ccagatttta cgcgtgttat ttgagcatgc aggcaacatc
    61381 gtagcacgtg acgacctgat gcgggaactt tggaacagtg actttttcat tgatgataat
    61441 accctctctg tcaatgtggc tcgtttgcgt aaaaagttgg aggagcaggg attggtagga
    61501 tttatcgaga ccaagaaagg aatagggtac ggattgaagc atgcttgatt ggaaacaatt
    61561 ttttctagcc tatctgcgct cccgtagtcg tctttttatc tatctgcttt ctttggcatt
    61621 tcttgtctta ctctttcagt ttttatttgc cagtctagga atttacttcc tctacttttt
    61681 cttcttgtgt tgctttgtaa ccatattatt tttcacttgg gacatattgg tggaaacgca
    61741 ggtctatcgc caggaacttc tctatggaga gagggaagcc aagtctcctt tggaaatagc
    61801 tttagcagaa aaattagaag cgcgtgagat ggaactctat cagcagaggt caaaagcaga
    61861 aagaaaactg acggatttgc tggattacta taccttgtgg gtccatcaga taaagacccc
    61921 cattgcagcc agtcaactct tagttgcaga agtggtcgac cgccaactga agcagcaact
    61981 agaacaggaa attttcaaaa tcgactccta taccaaccta gttttacagt acctgcgttt
    62041 agaaagtttc catgatgatt tggtcttaaa gcaggttcaa attgaggact tggtcaagga
    62101 aataattcgt aaatatgctc ttttctttat tcaaaaaggc ttaaatgtca atctacatga
    62161 ccttgataaa gaaatcgtga cggataaaaa gtggctgcta gtggttattg agcaaatcat
    62221 ctcaaacagt ctcaagtaca ccaaggaagg tggtctggag atttatatgg atgaccaaga
    62281 gctttgtatc aaagatacgg gaatcgggat aaaaaacagt gatgtcctcc gagtatttga
    62341 acgtggcttt tcaggataca atggccgttt gacccagcag tcctctggac ttggccttta
    62401 tctatctaag aaaatttctg aagaactggg gcaccagatt cgtatcgagt ctgaggtcgg
    62461 aaaaggaacg acagtgcgga ttcagtttgc tcaagtgaac ttagtccttg agtaaaaata
    62521 gatgagaaaa agcctccaga ttggaggctt ttatgctaga ctcttatttc tcaacgcgtg
    62581 atttgttggc gatatcagct aggatagctt gaacaaaatt atcaactgag acagtttgtg
    62641 tttctttttg gccgtagcga cgaacgttga ctgtttcgtc ttccatttct ttgtctccaa
    62701 caattaattg gtaaggaatc ttgctggttt gtgaagcacg aatcttgaac tgcatttttt
    62761 cattgcgctc atctacgtct gcacggacac cgcggtcacg gagtttcttg gccacttccc
    62821 aagcgtagtc cacgtgtttt tcgttagata ctgggatgag ggttacttgg tgtggtgcca
    62881 gccatgttgg gaaggccccc ttgtagttct caatcaagat agctgtgaag cgttccatag
    62941 ttgagataac cccacggtgg atcatgactg gacggtgatc ttcgccatca gctccgatgt
    63001 atttgaggtc gaagcgttct ggcaacaaga aatcaagttg gatagtagaa agggtttctt
    63061 cttttccaag ggcagtttta atctggatat ccaattttgg tccgtagaag gctgcttcac
    63121 cttcggcttc aaagtagtcc acgcccattt catcaagagc tgcacgaagc atggtttggg
    63181 cattttccca catctcatcg ttatcaaagt acttatgagt atcttgaggg tcacgaagag
    63241 agaggcggaa gcggtagtca gtcaagttga agtcttcata aacatcgata atcaactgaa
    63301 gggcacgttg gaattcttct tggatttgtt ctggagtaac gaataggtga ccgtcgttga
    63361 gtgacatttc acgtacacgt tgaaggccag tgagggcacc agatttttcg taacggtgca
    63421 tcataccgat ttcagcgata cggattggca attcacggta agagtgaaca tggtgtttga
    63481 aaacttggat gtggtgcgga cagttcattg gacgaaggac aaattcttcc ccgtcaccca
    63541 tgtccatggt tgggaacatg tcttcttggt aatgatccca gtgaccagaa gtcttgtaaa
    63601 gctcaacaga agcaagtggt ggagtgtaga cgtgttggta gccagaagcc aactctttgt
    63661 ttacgatgta gcgttccaat tcacgacgga tagtcgcacc atttggcaac cagaatggca
    63721 aaccttgtcc cacttcttgt gaaatcataa agaggtcaag ctctttacca agtttacggt
    63781 ggtcacgttc cttagcttct tcacgcattt gaaggtagtt tttcaagtct ttcttgtcaa
    63841 accaagctgt accgtagata cgttgcatca tagcgttgtc gctgtttcca cgccagtacg
    63901 caccagctac atggagaagg tggaagattt ggatacgacc tgttgatgga acgtgaggtc
    63961 cacggcagag gtctacatat tcaccctgac gatagatagt caaaccgcct tcgtcttctg
    64021 agtgttcttc aatcaattcc aacttgtaag ggtcattttt gaagatttca cgtgcctcgt
    64081 ctttagtcac ttcttcacga atagatggga agttttcttt gacgattttt tgcatttctt
    64141 cttcgatacg aggaaggtct tcgttagaga tttgaccagc tgtgttgtca gtatcgtagt
    64201 agaaaccatc ttcgatggct ggaccaactc ccaagtgaat gtctgggaaa agacgacgag
    64261 ctgcttgggc gaacaagtga gctgctgagt gacgcaagat tggaagggca tcttcgtgat
    64321 caggtgtcac aatttcgatg cttccatctt cagtgatagc gcgagtagtg tcgatgagtt
    64381 tgccgttgaa tttaccagcc aaggcttttt tagctaggga attgctgata gattgggcaa
    64441 tttcaaaagt tgttacgcca gattcgaatt cacgaacagc gccatctggg aaagtaatgt
    64501 taatcatgat gttctccttt tttattattt catagtttct aagcattgat tttttatcag
    64561 cagactactt ccaagtccta acgttcaatt gcttttcttt atcagagagg aagttttcca
    64621 tttccgtcag aatgtctata tccaaacgtt gagaaagttc taatagccac cagatatttt
    64681 ctgaaagttt ttgttccagt gtgtagggtg tttcatcata gtagcgtcct tgatttgtca
    64741 tcaccagtcg ttggaaattt ccaatatcat tagataaagc caagaggtct tcttctaccg
    64801 tccacttgaa atcatgatgc ttaacttcca gttcgtgata agcttgtcgg attgcccaac
    64861 tgcgctccac taattcttgc aactccataa ttagtatcct aataaaaaaa tgcgacatcc
    64921 tcgaaaggac gtcgcaacgt ggttccacct tcatttatgt acctcaaaag agagggacac
    64981 ctctgatcgg ctctaacgtg gccaccgttt tatgttttca taaaaaactc aagagtagta
    65041 tcagtttaga cttcctatgc gtttccagca accacgcact ctctagtaga aagggactaa
    65101 gtgacttgtc tctatggatt attatagcat gattgtgaga tttttcaagg attttgtgaa
    65161 agttttttgt ttttcatatt ttgtagaata tgcttgatgc taataccaga atccatgccc
    65221 accagagcaa ctgtttcata gattagcaag taaattagta taaactcacc aaaggttatg
    65281 atagtaaagt aaaagagcag tccgttacca actaaccatc aaagtgagaa acggaaacgg
    65341 tagctataga gtaacgatac aatcaagatt accagaggtg taaagaagag aagattgttt
    65401 atatagtgta aaggggtcag aaacaactag caagaacaac tcataaagtg gccaataaaa
    65461 gaataatatg accagatagt aggggagatg ggaatagaat ctacgcatga taatcacctc
    65521 gttttaaaaa aacagacaac ttagatctct tgctatgatt attatagcat gtttaaaaca
    65581 agaaagtaaa tttgttgaca aagaagattt ttcttttcac tagaatcata gttagttttc
    65641 ttggtagaaa tattttgata ataattaagc aagactattg atattgatta ttaagagtgt
    65701 cacatttgtt gtaactaaaa taattacaac aatagaggta taaaaaatga aactagcagt
    65761 tattgcagca aatggacaag cggggaaagc aattgttgaa gaagcagtca aacgaggaca
    65821 tgaagtaacg gctattgttc gttctgaaaa caaaagtcaa gctgagtcta ttattaaaaa
    65881 agatttattt gagttgacaa aagatgatct tactggattt gatgctgtta tttcagcgtt
    65941 tggtgcttat acaccagata cgctaccgct ccacagcaaa tcaatcgaac tatttaatca
    66001 gcttcttgct ggaacacaga cacgttttct agttgtaggg ggagcagaaa gtctttatat
    66061 agatgaaaca aaaacgacac gacttttaga tacgtctgat tttcctgaag aatttaagtc
    66121 actagcaaaa gctcaagcgg atgaattgga tcttcttcgt acaaaaaata atctcaactg
    66181 gacttttgtc agtcctgctg tagattttat tcccgatggt gaaaaaacag gaaactacat
    66241 tctagcagga gaaattttta ctactaatga aaaaggaata agccagatta gttatgcaga
    66301 ttatgctatt ggattggtag atgaacttga aaaaggtcat catataaaag aacgtatctc
    66361 tttacttgaa aaataataac tatgagagta ttaatgtttg acagaaaatt taaatcttgg
    66421 taaaataggg attgtcgtaa agacaaataa cttcttcttg gttacaggca tgccaacctg
    66481 tcactcggat gaagccaaat aaaaaggaga aacatcatgg caatctcaaa agagaaaaaa
    66541 aatgaaatca ttgcacaata tgcacgtcac gaaggtgata caggttcagt agaggttcaa
    66601 gttgctgtcc ttacttggga aatcaaccac cttaacgaac acatcaaaca acacaaaaaa
    66661 gaccacgcta cttaccgtgg attgatgaaa aaaatcggtc gccgtcgtaa cttgcttgca
    66721 tacttgcgta aaaacgacgt taaccgttac cgtgagttga tcaactctct aggacttcgt
    66781 cgctaattca agatacaaat gctgtcaaaa gcacaaagca aaaataggaa aattgacgaa
    66841 gaaacttcag tttctaggag attttatctt ttttgccaag tgcttaggcc gtgttcaatt
    66901 gagcatatct tgataatgaa gctactctaa attgggtagc ttttttgcgt tgtcacctta
    66961 cctcgatata ctcaagtata atctttggtt acggttccta gcactgtaag gtaaaataaa
    67021 ccagcttttc tcccttcggg gagatttttt ttgtttcact gaaagtttcg tacgatcttc
    67081 gcctcgtcgc ctagtctata aacgatttat ctagcaagaa tcatgatgct aagggcgtca
    67141 aaaatccgta tgaaaatagg gaaatgacac agtgttcgat gagcacaagg agtttcatct
    67201 ttttcactag gattttagcc cgggctcaaa tcagctctct gacttcagag ggctttttta
    67261 ttgaggtttt atcggtaaca attttggaga ctacaaaaac ctcaaacggt atcagctaat
    67321 tacaccataa aggtgcgcag ttactcggct tttcaagccg agtaactgta tgcaagcccc
    67381 ctagaagagc ccactcttta caaagtaaag tatagtatgt tatactttac atggaagtag
    67441 tcactgaatt ccagttagaa attactttgt aactacgttt tgaggaggag taaaatgctt
    67501 tcctacgttc gacattaccc actagcgata gctaaattaa tgtgtctgtg ctctcctaaa
    67561 atctgctgat ttattactga ctaatacagg aggttttttt tatgggacag acaatcatat
    67621 ctgctattgg tgtttatatt tccaccagta tcgattattt aattatttta attattttat
    67681 ttgcacagct atcacagaat aaacagaaat ggcatattta tgcggggcaa tatctaggca
    67741 caggcttact tgtaggggcg agtttagttg ctgcttatgt cgttaatttc gtgcctgaag
    67801 aatggatggt tggattgctt ggtttaatcc ctatctattt agggattcgc tttgcaattg
    67861 ttggagaaga tgcggaagaa gaagaggaag aaattattga aagattagaa caaagcaagg
    67921 caaatcaact gttttggaca gttacattgc tgacaattgc gtctggcgga gataatttag
    67981 gtatctatat accttatttt gcttcgttag attggtcaca gaccctcgtg gccttgcttg
    68041 tgtttgtaat cggcataatt atcttttgcg agattagtag ggtgttatcc tctattccgt
    68101 taatattcga gacaattgaa aaatacgagc gaatcattgt gcccttagta ttcattctac
    68161 ttggactata catcatgtat gaaaatggca cgatagagac ttttctgatc gtgtagattt
    68221 ttttgtttca ctaggatttt agcccgagct caaatcagct ctctgatttt cagagggctt
    68281 tttcattgag tataaatgga caatcttaaa gttactctat tgtagagtgg cttttgattt
    68341 gattaggaga ttcttataaa tatagtaaaa tgaaataaga ataggacaaa tcgatcagga
    68401 cagtcaaatc gatttctaaa aatgttttag aagtagaggt gtactattct agttccaatc
    68461 tactatataa atgaaaacct tagctgtttg gccaaggttc atttcttcta tgcaagttct
    68521 tctcttttct tatctgggtt ccagatgaag cttgcgataa agctaaagat gatggttagg
    68581 atagcgagga taatagcaag gatgagggca gggatgcgga taaaccacca gagtggattt
    68641 ggttttttat cattgtgcca ttgtttcgtt tcttcgtcca gacgttggaa ttctgtttga
    68701 atacgattgg cgactgtttc aatgccttca tcattcattt tcttgatatc tgagatatcg
    68761 attggatttc caaagttcat atcgacacgt tcacggctaa tcaagccctt caaagtcatg
    68821 ggaccggtgt aggtaaccgg catgatacgg accttggcca ttttggcaat cagtgctgcg
    68881 ccccccttga catcgtttga gtggcggcta ccacttggaa acatgatgag agagcggtca
    68941 ctttttttga gaacgttgat aggatatttg atggctgagg cgctgggatt ttcacggtcg
    69001 atgggaaagg cgccacacat acgaatccac caaccaaaga tacggttggt aaagagttct
    69061 ttttttgcca taaagatgaa ctgttttggc ttggtcgcaa aggccatata aacaggatcc
    69121 caccaggtac ggtgaggcgc aactaaaata taattttcat cttgattagg aattttatca
    69181 gtattatgat agtgagcatt gccattgatg gaccataaga gcagtacaac taatccacgc
    69241 aaataagtat aaaacatgcg atctccttcg attgttttct tgttattatt ataccttatc
    69301 aaaggagggc tggcaaactt ttcccttgac tagatacata tttaggatga aattagaatt
    69361 ctgttaaaaa aaatgatata atagaattta tggataaaaa taagattatg ggattaaccc
    69421 aaagagaagt caaggaaaga caggctgagg gtttggtcaa tgactttacc gcatcagcca
    69481 gtaccagcac ttggcaaatc gttaaacgaa atgtctttac cctttttaac gctttgaact
    69541 tagccattgc tttggctctt gcctttgtgc aggcttggag caatctggtc ttctttgctg
    69601 ttatctgctt taacgctttt tctgggattg tgaccgagct acgagccaaa cacatggtgg
    69661 acaagctcaa tctcatgacc aaggaaaagg tcaaaaccat ccgtgatggt caggaagttg
    69721 ctcttaatcc tgaagaatta gtgctaggag atgtcattcg tttgtctgca ggagagcaga
    69781 ttcctagtga tgccttggtt ttggaaggct ttgcggaagt caatgaagcc atgttaacgg
    69841 gagaaagtga tttggtgcaa aaggaagttg acggcttact tttgtcagga agtttcctag
    69901 ccagtgggtc agttttatct caagttcacc atgtcggtgc agacaactat gctgctaaac
    69961 tcatgcttga ggctaagacc gttaaaccca tcaactcccg tatcatgaaa tcgctggaca
    70021 agttggctgg ttttactggg aagattatca ttccctttgg tctggctctc ttgctggaag
    70081 ccttgctttt aaaaggcctg cctctcaagt catctgttgt aaactcgtcg acagctcttt
    70141 tgggaatgtt gcctaaggga attgcccttt tgaccattac ttcgctcttg actgcagtta
    70201 tcaagctagg tttgaaaaag gtcttggtgc aggagatgta ctctgttgag accttggcgc
    70261 gcgtggatat gctctgtctg gacaagacgg gtaccatcac ccaaggaaag atgcaggtgg
    70321 aggctgttct tccgttgacg gaaacgtatg gtgaagaggc tattgccagc atcttgacta
    70381 gctacatggc ccatagtgag gataagaatc caactgccca agccattcgc cagcgttttg
    70441 tgggagatgt tgcttatcct atgatttcca atcttccctt ctccagcgac cgcaagtggg
    70501 gggctatgga gttagaaggc ttggggacag ttttcttagg ggcacctgag atgttgctgg
    70561 attctgaagt cccagaagcc agggaggcct tggagagagg atcacgtgtc ttggtcttag
    70621 ctctcagtca ggagaaatta gaccatcaca aaccacagaa accatctgat attcaggctc
    70681 tagccttgct ggaaatcttg gaccccattc gagagggagc agcagagacg ctggactatc
    70741 tccgttctca ggaggtagga ctcaagatta tctctggtga caatccagtt acggtgtcta
    70801 gcattgccca gaaggctggt tttgcggact atcacagcta tgtagattgc tcaaaaatca
    70861 ccgatgagga attgattgct ctggcggagg agacagcgat tttcggacgt gtttcccctc
    70921 atcaaaagaa actcatcatc caaacgttga aaaaagcggg tcatacaacg gctatgacag
    70981 gggacggggt taatgatatc ttggcccttc gtgaggcgga ttgttctatc gtgatggcgg
    71041 agggggatcc agcaacccgt cagattgcca atctggttct cttgaactca gactttaatg
    71101 atgttcctga gattctcttc gagggtcgtc gcgtggtcaa taacattgcc cacatcgccc
    71161 cgattttctt gataaagacc atctattcct tcctgttagc agtcatctgt attgccagtg
    71221 ctttactagg tcggtcagag tggattttga ttttcccctt cattccgatc cagattacca
    71281 tgattgacca gtttgtggaa ggtttcccac cattcgttct gacttttgag cgaaatatca
    71341 aacctgttga gccaaatttc ctcagaaaat ccatgcttcg tgccctacca agcgctctca
    71401 tggtcgtgtt tagcgtcctg tttgtgaaaa tatttgggag tagccaaggt tggtctgagt
    71461 tagaaatctc aactctcctc tattatctct tggggtcaat tggtttctta tccgtattta
    71521 gagcctgcat gccattcact ctatggcgag tcctattgat tgtctggtca gtaggaggct
    71581 tcctagccac agctctcttc ccaagaattc aaaaactgct tgaaattgca accttaacag
    71641 gacaaacatt acctgtttat ggtgtcatga tgttggtctt taccgtgatt ttcatcctga
    71701 ccagtcgtta ccaagagaaa aaataaagaa agactgcaat ctgtggattg cagtttttta
    71761 tacgatggat ctatcgtaga tctgatgtgc aaggcctacg tgtctattat ctatcggtga
    71821 acccaagagt gattctcaag cctgcttgga ttgaggtaat agattcaaat atctgtagtt
    71881 agactatttg aagtttgatg taagaaagag aaagcgacag attgaagtaa ttttagctct
    71941 cttctattgc tagaacaaat ggtcggatag gttggtagtt tgaaaatgaa gatgctatct
    72001 attgttaaat ggaacatagt gttatttatt agaaaatcgt ttggtttatt tcttatcaaa
    72061 tacgaaaagc aacttaaata tttcaactaa aatagatgtt atgaagaaaa ggtaaaatga
    72121 ttttggcata gtgaggttct gttctatttg atatcatatt tttgataaaa acaaaaatgt
    72181 ccattgcaaa ggacaaaatg cgaagtatat tattttttga aagcgatata atggaatcat
    72241 aaaggaggtg tatcgtgtct agaaaacaag aacaaatgga aacgttgttg ctccttttgc
    72301 gagatagtaa ggattatata tctgctaaag tattgggaga aaaattaaat tgctctgata
    72361 aaacggttta tcgccttgtc aaggtaatca acaaagattg tccggtagaa gcattcattt
    72421 tatctgaaaa aggcagaggt ttcaaattaa atccaagaag ttccctcgtg gacgttgatg
    72481 ggaattttac agaggctttt gatcctgaag taaggcgtga aaaattacta gaacgtcttt
    72541 tgttgactgc tcctaagcca cattctattt atgatttagg agaggaattc tacgtaagcg
    72601 agtcagtagt actaaaagat cgtcagatat tacaagagag tctagcaatt tatgggttag
    72661 atttaaaaat gagacaacga aagcttttta ttgatgggga tgaggctcaa attcgttcag
    72721 ccattctaaa tctactgcca atgtttaatc agttggattt agagcaaatt acacagaata
    72781 aggttcagcc tcttgacgga gaacttgctc acttttgttt gggattactg attacacttg
    72841 agagagaatt gggggtaaac attccctatc catataatat aaatattttc tctcacctgt
    72901 atatttttat cagtaggaat cgtcgtagta ctagtattca tgttgtagca ccttcaaaac
    72961 ctactattgt tgatgagaaa atttacagtg tctgtcaaaa aattattcaa gaaattgaac
    73021 aatattttaa gatgaaggtt gatgcagttg agattgacta tctttatcaa tacgttgtat
    73081 cttcgagatt gcaaaaacca ttttcttccg ggaagcttcc tttttctcag cgagttttag
    73141 atgtcactca ttactatttt agccgtatgt gtatggacaa tagagagatt gaaacgacag
    73201 atcctgactt tgttgacttg gcgagtcata tcagtccctt actgaggaga ttagataata
    73261 gagtacagat taagaatagt cttttatcac aaattctttt aacctatcct aatctggtta
    73321 aagagttaac aactatttct aaagaagtga gtctagtatt tggttttgcg tccttgagtc
    73381 tggacgagat tggttttcta gtcttatatt ttgcacggtt tcaagaaaag cgagcacgtc
    73441 ctctaaaaac agtagtgatg tgtacatcag gtgtcggaac ttcagagctt ttacgagcac
    73501 gattagaaaa gcaattttct gaattggata ttattgatgt agttgcttat catcaattag
    73561 atgagctgat aaatctatat ccagatttag atttcattgt gacgacggta gctttgcagg
    73621 aaccagcaag tgtcccgttt gtcctagtta gtgcttttct aaccgagggt gataaacaac
    73681 gtcttcaagc aaaaattcag gagataaact atgaataatc tttcgcttgt ccttatggat
    73741 atatctgttc aaaatcgtca agaagcctac aaagaattag caaatcaaat cagccttctt
    73801 gtttctgaag atacagaaaa aatagaagag cttctatatt accgtgagag acagggaagt
    73861 atagaggttg ctaaaggtgt tcttctacca cattgtgaag gaaactttca acatcatgtc
    73921 ttagtgatta ctagattaaa accacctatc agagaatggt cgaaggatat ccagtgtgtt
    73981 gaccttatta tcggtttggc cattgcagta tcacaggaca agtcatgtat taaaacattg
    74041 atgagaagac tagcagatga atcattcata aatcaattaa aacagttaac aaaagaagaa
    74101 ttacgggaga taatatatgg aaatcaaaga tattcttaat gtgagtctga tccagacgga
    74161 tttacagatg cagagcaaag aagaggtttt tgaggcatta gctcaactat tggttgagac
    74221 gggttatgtg tctgatagag accaatttat cgaaggtctt tatcagagag aggcagaagg
    74281 acagactggt attgggaatt atattgctat tccccatagc aagagttctg ctgtggagaa
    74341 ggcgggggta gtcatagcta taaatcacaa tgagattcct tgggagacca ttgatgggaa
    74401 aggggtcaaa gtaattgtac tctttgcagt tggtgatgat acagaagctg ctagggagca
    74461 tttgaagacc ttatcactct ttgctcgaaa acttggtaat gacgaagttg ttgccaaatt
    74521 agttcgggct cagacatctg atgatgtgat tgcagctttt tgttaataag aaaaaatttt
    74581 ggagggtatc cgtatgaaaa ttgttggtgt tgcagcttgt actgtgggaa ttgcccacac
    74641 ttatattgca caggaaaaat tagagaatgc cgcaaaggta gctggacatg tgattcatgt
    74701 tgagactcaa gggacaatag gggtagaaaa tgaattgagt caagagcaga ttgatgcagc
    74761 ggatgtagtt attttagcag ttgatgttaa gatttctggt atggaacgct ttgagggtaa
    74821 aaagattatc aaggttccaa cagaagtggc agtcaaatct cccaataaac tgattgctaa
    74881 agctgttgag attgttacga aataactgaa aatatttaag gagaaaatat atgttgaaac
    74941 acttaaactt aaaaggtcac ttattgacag ccatttccta tatgattcca attgtttgtg
    75001 gtgcaggatt cttagttgcc attggtttag caatgggggg tggtgttcct gacgctcttg
    75061 tagcaggaaa attcactatc tgggatgctt tagcaactat gggtggtaaa gcccttggtc
    75121 tcttgccagt tgttattgct acaggtttgt cttactcgat tgctggtaag ccagggattg
    75181 caccaggttt tgttgttggt ctaattgcca attctgttgg ttcagggttt atcggtggta
    75241 tcttgggagg ttatatagct ggtttcttgg ttcaagcgat tattaaaaag gtcaaagtac
    75301 caaactggat taaaggttta atgccaacct tgattattcc ttttgtagcc tctttggtaa
    75361 gtagtttgat tatgatttat attattggag cgcctatcgc agcctttacc aactggttga
    75421 cgagcttatt acaaagcttg ggaagtgctt caaatggttt gatgggggca gttattggag
    75481 ttctcagtgc tgttgacttt ggtggcccac ttaataaaac agtctatgcc tttgtgttga
    75541 ctttacaggc tgaaggtgtg aaagaaccat tgactgcttt gcaattggtg aatactgcta
    75601 caccagttgg atttggattg gcctatttta tcgcgaaatt actcaaaaaa aatatctata
    75661 ctcaagagga aatcgaaaca ttgaaatcgg ctgttcctat ggggattgtc aatattgttg
    75721 aaggtgtaat tccgattgtt atgaataact tggttccagg tctcattgca acaggtatcg
    75781 gtggtgctgt tggtggtgct gtttctttga caatgggtgc tgattctgcc gtgccatttg
    75841 gtggagtgct tatgttacca accatgactc gtccagtagc tggtatttgt gctttgttag
    75901 ccaacattgt agtcacagga cttgtctacg cgattttgag aaaaccaata aaacatacag
    75961 aaccagttat gactgttgaa gaagagattg atttgtcaga tattgaaatt ttgtaagagg
    76021 gtaacgatgt caagaattga attttcacca tctttgatga ccatggattt ggacaaattc
    76081 aaagagcaga ttactttttt gaatgataaa gtagcatctt atcatatcga tattatggat
    76141 ggccattttg ttcccaatat taccttgtct ccttggttca ttcaagaagt tcaaaaaatt
    76201 agtgacacac ctttatcagt tcatctgatg gtcacagacc caaccttttg ggtagatcaa
    76261 gttctcgatt tacaatgtga gtatatttgt attcatgctg aagttctgaa tggtcttgct
    76321 tttcgtttga ttgataaaat tcatgatgca ggtctaaagg ctggtgttgt ccttaatcct
    76381 gaaacacctg tttctacaat ctttccctac attgatttac ttgacaaagt aactattatg
    76441 actgtagatc caggttttgc aggacaacgc tttttggagt ctaccttgta taaaatccaa
    76501 gaactccgtc agcttagagt tcagaatggt tatcactaca tcattgagat ggatggttct
    76561 tcgagtcgta agactttcaa acaaattgat gtggcaggac cagatattta tgttataggt
    76621 cgcagtggat tatttggttt ggatgacgat attgccaaag cctgggatat ctgttctaga
    76681 gattacgaag aaatgaccgg aaaaacaatg ccaatcaaat aatggtttga gaagaaattt
    76741 attagttagg aggaatatat gtcactacaa tcagttaacg ccattcgttt tcttggcgta
    76801 gatgctatta acaaatctaa ttctggtcac ccgggaatcg tcatgggtgc tgcgccaatg
    76861 gcttatagcc tatttacaaa gcaccttaga attacacctg agcagccaaa ctggattaac
    76921 cgagatcgct ttatcttgtc tgcgggtcat ggatcaatgc tactgtatgc tctcttgcat
    76981 ttaacagggt ataaggatgt atccatggac gagattaaaa atttccggca atggggatct
    77041 aagacacctg gtcatcctga agtgacgcat acgtctggtg tggatgcgac atctggtccg
    77101 cttggtcagg ggatttctac tgccgttggt ttcgcccaag cagagcgttt tttagctgct
    77161 aagtacaaca aagatggttt tcctattttt gaccattata cttatgttat cgctggagac
    77221 ggtgacttca tggaaggagt gtctgcggag gcggcttctt atgcaggtca tcaagcttta
    77281 gataagctta tcgtcctcta cgactccaac gatatctgct tggatggtga gaccaaagat
    77341 actttctctg aaaatgttcg cgcccgttac gatgcttatg gttggcatac agttctggta
    77401 gaagatggaa cagatttagc agcaatttct acagcaattg agacggccaa gttttctggt
    77461 aagccgagtt tgattgaagt gaaaacggta attggttacg gctcacccaa taaaagtggt
    77521 acaaatgctg ttcatggtgc accactagga gcagaagaaa caggagcaac tcgtaagttt
    77581 ttgggatggg attacgatcc atttgaagta ccagaggaag tatattctga tttcaagaca
    77641 aatgtagcgg atcgtggtca ggaggcatac gatgcttggg ctagtttggt gtctgattac
    77701 aaggttgctt atcccgaagt tgctagtgag attgacgcta ttgtagctgg aaaatcccct
    77761 gtaaccatta ctgaaaaaga cttccctgtc tatgagaatg gcttctctca agcaactcgt
    77821 aattcgtccc aagatgctat taatacagca gcagcagttt taccaacctt cttaggtgga
    77881 tcggcagact tagctcactc caacatgacc tacatcaagg cagatggctt acaagataaa
    77941 tataatccat taaaccgcaa tattcagttt ggggtacgtg aatttgccat gggaacaatc
    78001 ctcaatggaa tggctcttca tggtggttta cgagtttatg gcggaacctt ctttgttttc
    78061 tctgactacg tcaaagctgc tattcggcta tcagccattc aggagttgcc tgtaacttat
    78121 gtctttaccc atgattcaat tgccgttggt gaagatggtc caactcatga accagttgaa
    78181 catttggcag gtttacgctc aatgccaaac ttgactgtta tccgtccagc agatgcccgt
    78241 gaaactcaag cggcttggca tcatgccttg accagtacca ccactccaac tgtcattgtc
    78301 ttaacccgtc aaaacttggt agttgaagaa gggacagact ttggtaaggt cgctaaagga
    78361 gcctacgtcg tgtatgatac cccgggattt gatactatta tcattgctac aggatctgag
    78421 gtcaatctag ctatcaaagc tgctaaggaa ttggttttac aaggtggtaa agtacgtgtg
    78481 gtatctatgc cctcaatcga actatttgat gctcaagatg ctacctacaa ggaagacatt
    78541 ttaccatcta agactcgtcg tcgtgtggcc attgaaatgg cagcgaccca aagttggtac
    78601 aagtatgttg gtttggatgg cgcggtcatc ggtattgaca tcttcggtgc gtctgcccca
    78661 gctcagactg tgattgataa ttatggattt acggtagaga atatcgttgc tcaagttaag
    78721 tccctataga aaccaattac aatgaagata cagctgttgt cagactagca gatgtagtga
    78781 tagacactaa tcagatgatt ggttatttaa aaactataat gagaatgtaa taatttatct
    78841 acgaaagtta tagtagatag tatacacaat agagtatacc ctgaaacggt tgcgaagtac
    78901 gctaatcact ttgctactga tctagatagt ttctttaatc aataaacaca gcatccacag
    78961 attgacttag gatattgtaa gttttttgaa agctagagag aagatctcta aaattaaaaa
    79021 acgcatagta taggatgttg aaatgatgaa ctgcccccta aaagttagac agaaaaaatc
    79081 taacttttgg ggtgttttta ttatgaaa
//
LOCUS       DAVDHC010000007        77346 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVDHC010000007 DAVDHC010000000
VERSION     DAVDHC010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 77346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77346
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.007"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VUR43_000649"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VUR43_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET5412377.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VUR43_000650"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VUR43_000650"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET5412378.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VUR43_000651"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VUR43_000651"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET5412379.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VUR43_000652"
     CDS             complement(3790..5058)
                     /locus_tag="VUR43_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET5412380.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGELTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VUR43_000653"
     CDS             complement(5178..5546)
                     /locus_tag="VUR43_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET5412381.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VUR43_000654"
     CDS             complement(5539..5805)
                     /locus_tag="VUR43_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET5412382.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VUR43_000655"
     CDS             complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VUR43_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET5412383.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9373..9942)
                     /locus_tag="VUR43_000656"
     CDS             complement(9373..9942)
                     /locus_tag="VUR43_000656"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET5412384.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VUR43_000657"
     CDS             complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VUR43_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET5412385.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11248..12414)
                     /locus_tag="VUR43_000658"
     CDS             complement(11248..12414)
                     /locus_tag="VUR43_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5412386.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKDGSTVYKTVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIVPRRKEKEEQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALEWSDIDLKNGTLDVNKTLNIIKEITGPKTKSSIRVIDLDNKTVLMLRLY
                     KARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHA
                     SILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS"
     gene            complement(13420..14115)
                     /locus_tag="VUR43_000659"
     CDS             complement(13420..14115)
                     /locus_tag="VUR43_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HET5412387.1"
                     /translation="MRFNFDESGSITTSDKLNNRFFIVAGCQTNDPNKVKRVFRKAKV
                     KYLKHHPELELDIKKEIKGAQMPLDFKDYIFTELMKKTDIQFNFIVFDNHNAMEHLRK
                     KPNITFNYIMFLQVNKLIESYEHIYLDLDDRNKAVENLKALEEYLQTRLCAELNKIPD
                     INVQFFDSSQHTLIQIADVFSNHLFRIFKSVAYNQERSGDIKLLRKIHNRNVQYCQYF
                     PANKCQCLHLFSK"
     gene            complement(14287..15027)
                     /locus_tag="VUR43_000660"
     CDS             complement(14287..15027)
                     /locus_tag="VUR43_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412388.1"
                     /translation="MRSNSEIIDIIVLEKDKQDLSLSELARRVGLAKSAMSRYLNKTR
                     QFPLNRAQDFANVLGISVEYLLGVENSSPSTSTVEKITLIADQLTPPRQEKALTYLKK
                     QLLEQKNENIVSENIISLDDYRESKTLPVIGVVTAGNGITQDDNLNMEKCFYTDEIPD
                     DYDAIAYVVGNSMEPKIKNGDYLFIKNTPQVDYNTIGIFQVDGANYVKKLRQGYLESL
                     NPECADIQLDESNDIRTIGEVVSIYREN"
     gene            15208..15429
                     /locus_tag="VUR43_000661"
     CDS             15208..15429
                     /locus_tag="VUR43_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000217789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412389.1"
                     /translation="MELNLRRIKAERIAKGYTQDVIAEKMGWKSRAPYAKRENGIVPF
                     GADELAEFGKILGYGVNELGIFFNKNVPE"
     gene            15531..15716
                     /locus_tag="VUR43_000662"
     CDS             15531..15716
                     /locus_tag="VUR43_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001009512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412390.1"
                     /translation="MNFKEFKTWLDDAVSMAEAMALPENTGVLDDLIENAANNLAFIA
                     ELVENRQLIYRKPRHED"
     gene            16177..16629
                     /locus_tag="VUR43_000663"
     CDS             16177..16629
                     /locus_tag="VUR43_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412391.1"
                     /translation="MEETAYENLTRRIDRISAEMREIGEKTGLSRLSLLASQTEFIKE
                     ELSRLLWIELPELNDSHKIEAVSKSTTGIFFSPGIFEMDAMRKAFFKRQAKHFFDNEA
                     DQQAYIEHTEKEYLGATVTLKDILFNSKNGTQKANKSCLIEKFEEAMQ"
     gene            16626..16766
                     /locus_tag="VUR43_000664"
     CDS             16626..16766
                     /locus_tag="VUR43_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412392.1"
                     /translation="MTLDLGKMTQAEFDKQMAEIKERNPNIFQLISDFLDRKVTPEEV
                     DD"
     gene            16828..17043
                     /locus_tag="VUR43_000665"
     CDS             16828..17043
                     /locus_tag="VUR43_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412393.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPEYGRYIQLAGVNVWGGME"
     gene            17040..17381
                     /locus_tag="VUR43_000666"
     CDS             17040..17381
                     /locus_tag="VUR43_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5412394.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            17374..17649
                     /locus_tag="VUR43_000667"
     CDS             17374..17649
                     /locus_tag="VUR43_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412395.1"
                     /translation="MFSLSRESEHDLTHGILEVVERYLEAREKVPPRLTKLINRVELK
                     EELKISDNTLNKWESQGLRRYQPPDDGARIIFYLVDDIRRFMGVENG"
     gene            17789..18649
                     /locus_tag="VUR43_000668"
     CDS             17789..18649
                     /locus_tag="VUR43_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HET5412396.1"
                     /translation="MTIYEARGFQSNLVYPFDKMEPFQYIERFKPLVVPESADPEEYK
                     RTQAPYCLSGKVMPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTELYKPRASGQRSMTMRIIDTLF
                     NGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            18729..20183
                     /locus_tag="VUR43_000669"
     CDS             18729..20183
                     /locus_tag="VUR43_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HET5412397.1"
                     /translation="MWELYSRIWELGDQWRKENSYIVNEGKKNERVEIPRPSVAIVAK
                     ALQEICHFTFIGEGVISDISKLYLYHLDLGHYVSSNDIFRKLLLKYDSRLTSNKFFLE
                     LISYIRTETKMKPPLDDYRYIPVANGVYNIKTHKLEEFSPNFVITSKIQTEYNPCARK
                     PILDGWFDFDRWLEALAVNDKEVVALLWQVINEAINPNRTRKKMVLMVGDGNNGKGTF
                     QALLENLIGRSNISNLKPDQFGKEFYLGALEGKVCNIGDDISNKYLDEVSDLMSVISG
                     DPVQVNKKSLQPVEARFRLLCIFSGNDLPRARNKTMGWYRRLCIIPFRADFNGQKERH
                     EIKDRFIKNKELLEWVLFKVLNMPDFDSFIEPEAVQKMLSKYKNDNDYIKVWVENFYI
                     PNGWHEINHVPMFIARNKLKEFAEDIGIDKPKLGQFSNAVMAELEKTTSYKYSAKNGT
                     VSSKFYDVLDPQGFQRKRFVKGIWGIHLEDEDLG"
     gene            20793..20966
                     /locus_tag="VUR43_000670"
     CDS             20793..20966
                     /locus_tag="VUR43_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HET5412398.1"
                     /translation="MKIKLFYQKYKQALWDLESQVNGFMADVEVIDVKYTKATVGNSE
                     DMDTLTSVMVLYK"
     gene            20983..21141
                     /locus_tag="VUR43_000671"
     CDS             20983..21141
                     /locus_tag="VUR43_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HET5412399.1"
                     /translation="MEIQEGFIYFRNYGIIKLLEVPRFGSITLKIQDGEIVSSVESKT
                     TIFKKNTD"
     gene            21225..21824
                     /locus_tag="VUR43_000672"
     CDS             21225..21824
                     /locus_tag="VUR43_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412400.1"
                     /translation="MPTLQEVKNQMDKVRTQLEIFDRFDEEIKKAEQEVKAIKAKKAD
                     LQTFEDFQAINAKEKYIADMKAQRTKLEKERIDSIVADARKINASGYLETALEQDETV
                     KRQRQEIKQKSIELLELIANYNENYKNTAKRLADEVRETGIEELFDRLNTSPEYSGVS
                     KPYIYSGVAGYMGNQHRYLDPSDDLAYFVNRINLFEGEQ"
     gene            21824..22054
                     /locus_tag="VUR43_000673"
     CDS             21824..22054
                     /locus_tag="VUR43_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000650801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412401.1"
                     /translation="MKDEHKQLFQEIEEEKRQADLLQGLAKNVESISKSYEEEAVTLE
                     EFKAMGYKRRHELFEKDKALYDKLLGKEKRGL"
     gene            22118..22384
                     /locus_tag="VUR43_000674"
     CDS             22118..22384
                     /locus_tag="VUR43_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412402.1"
                     /translation="MVRSSKARLEKLEEYAGKTEYATTDECISLYVDCLRFAFQQDEI
                     KIDMDDFIKTPFKDIKLADYKKSKKRMDELKEMTGISEFPELEQ"
     gene            22435..22776
                     /locus_tag="VUR43_000675"
     CDS             22435..22776
                     /locus_tag="VUR43_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000035041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET5412403.1"
                     /translation="MANYLMTGNVKKASELSEITRKTAYNYLNDATFKRIYRERRSEQ
                     LKESTTLLQNASVEAVNVLREIMLDKTVSPYARQQSAQSILNMAYKAVEMVEVVEQLE
                     ILEAKILDEGD"
     gene            22763..23014
                     /locus_tag="VUR43_000676"
     CDS             22763..23014
                     /locus_tag="VUR43_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412404.1"
                     /translation="MKAIKNRLNKLNKLSVVDEVDTVFLTQIDTGHFEVRYRIGGKNP
                     KDIIEVYPTKEEAEKDISEIRNTKGLRIFWDNLALLEDD"
     gene            23369..23788
                     /locus_tag="VUR43_000677"
     CDS             23369..23788
                     /locus_tag="VUR43_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET5412405.1"
                     /translation="MTPEQVKEKLEGVKWINKEIKGLYLELEVLESGIIKKPTLSHSR
                     VQTSRENKTENNLISVLKLKEDTLQRIERLTEERMAISELIDKLANPLERSVLRLFYL
                     NDLVASEVAEEIDRSNTTVYRIKQEAIEHLTGIVNGD"
     gene            complement(24237..24431)
                     /locus_tag="VUR43_000678"
     CDS             complement(24237..24431)
                     /locus_tag="VUR43_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET5412406.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(24496..25632)
                     /gene="dnaN"
                     /locus_tag="VUR43_000679"
     CDS             complement(24496..25632)
                     /gene="dnaN"
                     /locus_tag="VUR43_000679"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET5412407.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(25791..27152)
                     /gene="dnaA"
                     /locus_tag="VUR43_000680"
     CDS             complement(25791..27152)
                     /gene="dnaA"
                     /locus_tag="VUR43_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET5412408.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(27365..28123)
                     /locus_tag="VUR43_000681"
     CDS             complement(27365..28123)
                     /locus_tag="VUR43_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET5412409.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(28181..29362)
                     /locus_tag="VUR43_000682"
     CDS             complement(28181..29362)
                     /locus_tag="VUR43_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET5412410.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            29545..30024
                     /gene="rlmH"
                     /locus_tag="VUR43_000683"
     CDS             29545..30024
                     /gene="rlmH"
                     /locus_tag="VUR43_000683"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET5412411.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            30068..30141
                     /locus_tag="VUR43_000684"
     tRNA            30068..30141
                     /locus_tag="VUR43_000684"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:30102..30104,aa:Arg,seq:tct)
     gene            30306..30431
                     /gene="comC"
                     /locus_tag="VUR43_000685"
     CDS             30306..30431
                     /gene="comC"
                     /locus_tag="VUR43_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET5412412.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            30452..31777
                     /locus_tag="VUR43_000686"
     CDS             30452..31777
                     /locus_tag="VUR43_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5412413.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            31774..32526
                     /locus_tag="VUR43_000687"
     CDS             31774..32526
                     /locus_tag="VUR43_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5412414.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            32578..32649
                     /locus_tag="VUR43_000688"
     tRNA            32578..32649
                     /locus_tag="VUR43_000688"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32611..32613,aa:Glu,seq:ttc)
     gene            32655..32728
                     /locus_tag="VUR43_000689"
     tRNA            32655..32728
                     /locus_tag="VUR43_000689"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32689..32691,aa:Asn,seq:gtt)
     gene            complement(32769..33311)
                     /locus_tag="VUR43_000690"
     CDS             complement(32769..33311)
                     /locus_tag="VUR43_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET5412415.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            33418..34595
                     /locus_tag="VUR43_000691"
                     /pseudo
     CDS             33418..34595
                     /locus_tag="VUR43_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(34625..37177)
                     /locus_tag="VUR43_000692"
     CDS             complement(34625..37177)
                     /locus_tag="VUR43_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET5412416.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPISYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(37239..38861)
                     /locus_tag="VUR43_000693"
     CDS             complement(37239..38861)
                     /locus_tag="VUR43_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5412417.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            39067..40092
                     /gene="trpS"
                     /locus_tag="VUR43_000694"
     CDS             39067..40092
                     /gene="trpS"
                     /locus_tag="VUR43_000694"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET5412418.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            40244..41722
                     /gene="guaB"
                     /locus_tag="VUR43_000695"
     CDS             40244..41722
                     /gene="guaB"
                     /locus_tag="VUR43_000695"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET5412419.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(41773..42870)
                     /gene="recF"
                     /locus_tag="VUR43_000696"
     CDS             complement(41773..42870)
                     /gene="recF"
                     /locus_tag="VUR43_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET5412420.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNRN"
     gene            complement(42873..43241)
                     /gene="yaaA"
                     /locus_tag="VUR43_000697"
     CDS             complement(42873..43241)
                     /gene="yaaA"
                     /locus_tag="VUR43_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET5412421.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            43400..44650
                     /locus_tag="VUR43_000698"
     CDS             43400..44650
                     /locus_tag="VUR43_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET5412422.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKGWIAKLEQV
                     DKDDICRAANNVKLQAIYFMEGIE"
     gene            44647..45930
                     /locus_tag="VUR43_000699"
     CDS             44647..45930
                     /locus_tag="VUR43_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET5412423.1"
                     /translation="MTKVVFEKKYYPAVKEMIYRTRLSNGLTVALLPKKEFKEVYGSV
                     TVQFGSIDTLVTEIDGDVKKYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDVSLSLEVEVTSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            45972..46793
                     /locus_tag="VUR43_000700"
     CDS             45972..46793
                     /locus_tag="VUR43_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5412424.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            46804..47349
                     /gene="pgsA"
                     /locus_tag="VUR43_000701"
     CDS             46804..47349
                     /gene="pgsA"
                     /locus_tag="VUR43_000701"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET5412425.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMSDKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            47346..48173
                     /locus_tag="VUR43_000702"
     CDS             47346..48173
                     /locus_tag="VUR43_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET5412426.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLSEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            48158..48997
                     /locus_tag="VUR43_000703"
     CDS             48158..48997
                     /locus_tag="VUR43_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET5412427.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            48990..49784
                     /locus_tag="VUR43_000704"
     CDS             48990..49784
                     /locus_tag="VUR43_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET5412428.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            49843..50661
                     /gene="mreC"
                     /locus_tag="VUR43_000705"
     CDS             49843..50661
                     /gene="mreC"
                     /locus_tag="VUR43_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET5412429.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            50661..51155
                     /gene="mreD"
                     /locus_tag="VUR43_000706"
     CDS             50661..51155
                     /gene="mreD"
                     /locus_tag="VUR43_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET5412430.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            51249..52427
                     /locus_tag="VUR43_000707"
     CDS             51249..52427
                     /locus_tag="VUR43_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET5412431.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            52651..53430
                     /gene="rpsB"
                     /locus_tag="VUR43_000708"
     CDS             52651..53430
                     /gene="rpsB"
                     /locus_tag="VUR43_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET5412432.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            53509..54549
                     /locus_tag="VUR43_000709"
     CDS             53509..54549
                     /locus_tag="VUR43_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET5412433.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            54795..55118
                     /gene="tnpB"
                     /locus_tag="VUR43_000710"
     CDS             54795..55118
                     /gene="tnpB"
                     /locus_tag="VUR43_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET5412434.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(55259..55567)
                     /locus_tag="VUR43_000711"
                     /pseudo
     CDS             complement(55259..55567)
                     /locus_tag="VUR43_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            55558..55956
                     /locus_tag="VUR43_000712"
     CDS             55558..55956
                     /locus_tag="VUR43_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5412435.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(56153..57073)
                     /gene="cysK"
                     /locus_tag="VUR43_000713"
     CDS             complement(56153..57073)
                     /gene="cysK"
                     /locus_tag="VUR43_000713"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET5412436.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(57358..57993)
                     /locus_tag="VUR43_000714"
     CDS             complement(57358..57993)
                     /locus_tag="VUR43_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET5412437.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            58049..59347
                     /locus_tag="VUR43_000715"
     CDS             58049..59347
                     /locus_tag="VUR43_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5412438.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            59344..60006
                     /locus_tag="VUR43_000716"
     CDS             59344..60006
                     /locus_tag="VUR43_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET5412439.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            60086..60634
                     /gene="raiA"
                     /locus_tag="VUR43_000717"
     CDS             60086..60634
                     /gene="raiA"
                     /locus_tag="VUR43_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET5412440.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            60770..62743
                     /locus_tag="VUR43_000718"
     CDS             60770..62743
                     /locus_tag="VUR43_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET5412441.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDETSESDISQINSFVANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDMKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEMKEKEKEE"
     gene            62740..63192
                     /gene="rplI"
                     /locus_tag="VUR43_000719"
     CDS             62740..63192
                     /gene="rplI"
                     /locus_tag="VUR43_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET5412442.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            63236..64588
                     /gene="dnaB"
                     /locus_tag="VUR43_000720"
     CDS             63236..64588
                     /gene="dnaB"
                     /locus_tag="VUR43_000720"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET5412443.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            64590..64856
                     /locus_tag="VUR43_000721"
     CDS             64590..64856
                     /locus_tag="VUR43_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412444.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            64945..66291
                     /gene="cbpD"
                     /locus_tag="VUR43_000722"
     CDS             64945..66291
                     /gene="cbpD"
                     /locus_tag="VUR43_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET5412445.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLASGTVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSHSSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGLWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      66374..66476
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            66547..66837
                     /locus_tag="VUR43_000723"
     CDS             66547..66837
                     /locus_tag="VUR43_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET5412446.1"
                     /translation="MKASIALQVLPLVQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            66800..67558
                     /locus_tag="VUR43_000724"
     CDS             66800..67558
                     /locus_tag="VUR43_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5412447.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            67597..68604
                     /locus_tag="VUR43_000725"
     CDS             67597..68604
                     /locus_tag="VUR43_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5412448.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            68604..69332
                     /locus_tag="VUR43_000726"
     CDS             68604..69332
                     /locus_tag="VUR43_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412449.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            69451..69909
                     /locus_tag="VUR43_000727"
     CDS             69451..69909
                     /locus_tag="VUR43_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET5412450.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            69911..72343
                     /locus_tag="VUR43_000728"
     CDS             69911..72343
                     /locus_tag="VUR43_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET5412451.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDSNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGNTLKI
                     GVKAGQLKFDIA"
     gene            72973..73626
                     /gene="rr06"
                     /locus_tag="VUR43_000729"
     CDS             72973..73626
                     /gene="rr06"
                     /locus_tag="VUR43_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET5412452.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            73623..74954
                     /gene="hk06"
                     /locus_tag="VUR43_000730"
     CDS             73623..74954
                     /gene="hk06"
                     /locus_tag="VUR43_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET5412453.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            75037..75564
                     /locus_tag="VUR43_000731"
     CDS             75037..75564
                     /locus_tag="VUR43_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET5412454.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            75664..75795
                     /locus_tag="VUR43_000732"
                     /pseudo
     CDS             75664..75795
                     /locus_tag="VUR43_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            75842..>77346
                     /gene="pspC"
                     /locus_tag="VUR43_000733"
     CDS             75842..>77346
                     /gene="pspC"
                     /locus_tag="VUR43_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HET5412455.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEEVGGRN
                     TPTVTSSGQDISKKYADEVKSHLEEMFSGIQLDRRKHTQNFNFNLKLSKIQTKYLREL
                     SVLKSKSELTLETKEELLSKTKAELDAAFEQFKKDTLKLGEKVAEAEKKVEEAKKKAK
                     AQKEEDHRNYPTNTYKTLELEIAESDVKVKEAELELLKEEAQTRNEDTINQAKAKVKS
                     EQAEATRLKKIKTDREEAEEEVKDKPKKRTKRGALGEPATPDKKENDAKSSDSSVGEE
                     TLPSPSLKPGKKVAEAEKKVAEAEKKAKAQKEEDRRNYPTNTYKTLELEIAESDVEVK
                     KAELELVKEEAKKPLNEGTIKQAKAEVESKKAEATRLEKIKTDRKKAEEEAKRRAAEE
                     DKVKEKPAEQPQPAPAPQPEKPTEEPENPVPAPKPEKPAEQPKPEKPAEQPKAEKTDD
                     QQAEEDYARRSEEEYNRLTQQQPQKPEQPAPAPKIGWKQENGMWYFYNTDGS"
BASE COUNT        24566 a        13082 c        15503 g        24195 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aagcatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 ttgctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca taatctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattgatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tccttttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatc ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccaatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agagtttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcataacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagccag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacataga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat tttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catacttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaatcc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aattccccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccaac ttttcatctg acaaacccaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttat agaagaaaaa tatcaaatgg aattttcttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgaa catcaaatac aagctccatt aattccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacagtcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg aatacaattc
     6421 aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc ctgctccacg
     6481 aatcgaaaga tctcgcattg caatcttaaa gccagagccc aattctgtaa atcctttaat
     6541 cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat acatgagata
     6601 agcataagca atacgattac tacgaccgac tcttcctctt aactgatata aggttgacaa
     6661 gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt ccacccctgt
     6721 ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt ctaatagagt
     6781 attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag cctccggaat
     6841 caactcctgt aattctgaaa ccttctgaac aattgtgtca actttgttgt aaagataata
     6901 aacttgacct ccacgctcca tttcacgcaa gacagcatca cgaatgacac tatcattctt
     6961 ttccaaaaca taggtctgaa caggatagcg attagtcggc ggagtttcaa taacagataa
     7021 atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag cggtcaaggt
     7081 taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga caccaaatcg
     7141 ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt ttgacaaaac
     7201 acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa gtgttgcagt
     7261 ctgctctttt ttacttctaa agcgactcaa cacatcaata ttaactgcaa aattttggaa
     7321 tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa ctagaatgac
     7381 aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt cagtctttcc
     7441 aaaaccaaca tccccaacta aaagtcgatc cattggctga gaagcctgca tatccctctt
     7501 gatttcctca atactacgaa gttgatcatc cgtttcaaca taagggaaag catcatcaaa
     7561 ggcatcttga tcatcatcat cagctgagaa agcaaaaccc ttcaactgac tacgttcaga
     7621 gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct tttgcttggc
     7681 ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat cacttgaaat
     7741 atatttggac agtagatgaa tctgttccac gggaatagaa atttgatcac cattttggta
     7801 ttggacactg acataatcac gatgaattcc cttgatttca atggtttcaa ttcctagata
     7861 ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt cattgtaatc
     7921 ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta atttcttttg
     7981 aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa aaccatgtct
     8041 gagattaccc tctattaagt ttacagattc tttacagata tttgtcttat ctctagaatc
     8101 caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca ttgaattgct
     8161 agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt cttttagaaa
     8221 agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa ttttgtcaaa
     8281 tttgagattt cctaaaccct tttgaagatt agaaaaaaag gtcactggac tttgtttttt
     8341 atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac tattctgtaa
     8401 ttcttctgta aagtactgcg ctaattctct ttcaaagact tcatactgat tcatcaattt
     8461 ttgataatca tcaaagaata ttggagtatc tttttcaata taatcaaaga cagtccatgt
     8521 cttatcatag cacaaagata aaaacttccg agagtctgca tgactttgtt tttggtgaaa
     8581 acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt ttgaaatttg
     8641 tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca tatcactagc
     8701 tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta cttcaaatga
     8761 cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta actgggatat
     8821 ttcaaaaata tctaaaatat ctcctcgaag actaaattcg ccctgagttt gtacttgagt
     8881 aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgat catattcttc
     8941 accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta aaatcaatcg
     9001 acttgctgcg atattacaaa ctaaaatccc tttcttagat gaatcagtca aaaaacgcaa
     9061 ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca ccataggagc
     9121 atcatctacc aaaaatggat agacgagttc ctcacccaag atagatataa gatcactaac
     9181 aagtccttct gcttctccat aagttgacat caataacaca atcctatctt ctttttctaa
     9241 actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta gttgtctttt
     9301 cttatctgtt aaattttgat gccatttttt aatctgatca ttttctgaga ataaatctaa
     9361 taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt tctcttgtaa
     9421 atagtagttt acagaatcgt caactttgtc aacagactgt aaaataccga tatactcatc
     9481 cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag gtcttccaat
     9541 tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag acttgatacc
     9601 attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt ccatgtcaag
     9661 atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta ataaagcatg
     9721 aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa ttttttctcc
     9781 atttaggaaa aaggatgcta ggtcagcttg aaatatctta tcgtgtgtaa aagtgacatt
     9841 ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg tttcaaaata
     9901 tttatcccct ggatttccca agcctacaag taatttggtc atttattttt cctttcaaaa
     9961 gccaaaaggg ttggaatttt tttccaacct aattgacacc atttattaat ttttagacat
    10021 taaagcggaa ttccatgata tcgccatctt gaacgatata ttcttttcct tcttcacgca
    10081 agcgtccagc ttcttttacg gccttttcag atccgtattt cactagatct tcatatgaca
    10141 tggttactgc acgaataaag cctttttcaa agtctgagtg gataatacca gctgcttgag
    10201 gagccttcat accacgtttg aaagtccaag cgcgaacttc tttttcacca gctgtaaagt
    10261 aagttcccaa tccaagcaag tggtaagctg cacgcgtcaa cttatctaca cctgattctg
    10321 tcaaaccaat ggcttcaaga aactcttttt tatcttcatc atccaattca gaaatttctt
    10381 cctcagcacg cgcagaaata acgactactt cagcattttc tgtcgctgca aattcacgaa
    10441 tttgtttgac atagtcgata gagtcaggtt ctgaaaccac atcctcgtcc acattagcta
    10501 cataaagaac tggtttagtc gtcaaaagga aaagaccttt gacaaccttt tgttcctcat
    10561 ctgtaaattc aatggtacga gctgatttcc cgtcttctag gactggttta atcttttgaa
    10621 gaacattaaa ttctgctact gattctttat ctttttgcgt acgtgccatc ttttctacac
    10681 gcgcatatcg tttgttcact gattctaagt cagcaagaat taattccaga ttaattgtat
    10741 caatatctgc aagtggatct acaaaggcgt cttcacgtcc ttgctcgcgc atcacatttt
    10801 catcatcaaa agcacgaact acgtgaacaa tcgcatctac ttcacgaata ttggccaaga
    10861 atttattccc tagcccttct ccttttgaag ctccttttac aatccctgca atatccgtaa
    10921 attcaaatgt tgtgggaact gtctttttag gagttatcat ttcagttagt ttttgtaggc
    10981 gttcatctgg aacttccacc attccaacat ttggatcaat agtcgcaaat gggtagtttg
    11041 ctgcctctgc tcctgctttt gtaattgcat taaatagtgt tgatttacca acgtttggca
    11101 aaccaacgat acctgctgtc aaagccatat ttctcattct ccgttttcat ttcaatccct
    11161 aatattataa cacaaaaagg gataaagcgc taaaattcct tgatatagct atttcccata
    11221 actgaaataa taattttatg gactttttta ggaacttttt aatttttcaa tggctttttc
    11281 ataaaatgaa gtagcatttt tctgattgtc tttggatagg tggctataaa tatccatggt
    11341 catagaaagt tttgcatgac cgagccgtgt ttgtatctct ttgtaaggta gtccagcatt
    11401 gagcaagata ctagcatgag tgtggcggaa ggcgtggaac gtaaaacgag ggcatccagc
    11461 acgttccaaa tgttttacta acctgaaact aagcattcta gcgtctatat gcttatcaaa
    11521 gctattagag aatactttct cataggtcaa ccccatttct ttccctattt gggattgtct
    11581 tgctttatag agccgtagca tgagcaccgt cttattatcc aagtcaatta ccctaatact
    11641 tgatttagtc ttagggccag tgatttcttt gataatattt aacgttttat ttacgtctag
    11701 tgtgccgttt tttaggtcaa tatcagacca ctctaaggct agacactcac gaatgcgcaa
    11761 accagtagct aaaagtgtct tatatagcac cgtatcgtag aaatttttgt aagtgtttgg
    11821 cagctgctcc aggtaagtca agaatttttt taagttatca tcatccagat atttcagttt
    11881 ttgctcttct ttttccttac gacgtggcac gataacatca cgggcagggt taaaggggat
    11941 agcttgcaaa gatacggcat atttaagtat gcgtttgttt agagagtgaa ggagcggata
    12001 ttcttggaat cctttgccta gttgattata gtcttttgcc cattgattga cttgcttttg
    12061 aatgattggg ggcgtcagtt tatccagcct ataatttccg aaagctggaa gtagatattt
    12121 atctattttg aatttggtac ccattaaggt cgatttttta accgtatggc agtacgtttc
    12181 tagccaattc tccaccagtt cggcgtaagt ctttatctcc accgtcttat atactgtaga
    12241 cccgtctttt tcaaagtcta tttgagcctg tagcgctttg gctttgagtt ctctcttggt
    12301 tcgccctgat atagtcgtct tgactttctt acctgttacg gtatcgatac caaggtagac
    12361 gctagagcga tagactgtag acccgtcttt tttggtgtat tctgttattt tcatggtttt
    12421 actccttttt ccatcagcag gcaagcaatt agaaaagatt ttgagtttat accatgcgag
    12481 gggctacgag aataccccta ttttcgattt taattagtca gacggtaaat tgtaccagaa
    12541 aagggaataa ggcagatatg ggacttatat gggcttgttt gtgatgggtg tttttgatat
    12601 aatgttttcg ccccctcaat ttagagaagg gaggtgttat atatgctaga gttgttttcc
    12661 ctttttctag ctccgttact tgttaacgtc ttatctgagc ttttcaagct atggataaag
    12721 agacgtagca agtagcattt aaccctttaa gagggtagca aaaaacccca tcgctggaac
    12781 ggtggggctt tttagttaca tatgctagaa gcactgtttt tccctttatg ctttcattct
    12841 agcatacgag ccccaatatt tcaagagttt tatttttttt tgatattgtt tagagcgctt
    12901 taagcgttcc taaaatgccg aagtgttgaa aatcgtctaa attataccgc attatacttc
    12961 attagagagt tatagactga tgagcgtgag aaatgccgtc agtcgctttt taaatgcaag
    13021 agtggtataa taatagcgta gactaagagg tttgaaagag tcccaactca acagtaacca
    13081 gacctttctg cttccaatct ctcaagatgc tactaatcgc ctgaatcttt cccgttattt
    13141 cagttcaggc gatattagac aagtcagcag cagctagctt gtcttttttt tgttgtagaa
    13201 aactagtgta gtaaaaagaa aagtgtacca acataataag ccgatacact gatttttttg
    13261 taaaatataa aagcccttaa ctgatagcag gttacccaat aggcaactta cgaaaaatac
    13321 gcagacatat cagaattaca agcgactttc taacatcact atatcgtttt ttttattaaa
    13381 aatcaacttt tttgtcgctt tttttgtact tttttatttt tattttgaaa ataagtgtag
    13441 gcattgacat ttattcgctg ggaagtattg gcaatattga acattacgat tatggatttt
    13501 tctaagtagt ttgatatctc ctgatctttc ttggttataa gctacagact tgaatattct
    13561 aaataagtga tttgaaaata catcagcaat ctggattagt gtatgttgtg atgaatcgaa
    13621 aaattggacg tttatatctg ggattttatt tagttcggca caaagtctag tttgtaagta
    13681 ttcttctaaa gctttaaggt tttcaactgc tttatttctg tcgtctaaat ctaaatatat
    13741 atgttcataa ctttctatca gtttattgac ttgcagaaac ataatataat taaacgttat
    13801 gtttggcttt ttccgtagat gttccatggc attgtgatta tcaaatacaa tgaagttaaa
    13861 ttggatatct gtttttttca tcaattctgt aaaaatatag tctttgaaat caagtggcat
    13921 ttgtgcccct ttaatttctt ttttaatatc taattctagt tcgggatggt gttttaagta
    13981 ctttaccttt gcttttctaa aaactctttt tactttgttg gggtcattcg tttggcaacc
    14041 agcaactata aaaaatcgat tattaagctt atcgctagtg gtaatgctac cagattcatc
    14101 aaagttaaat ctcaattgtt gctcctttta attttttaat tattgacaaa aacgctattt
    14161 tgttaataat tattttcttt tttgcgcttt agtctgtaaa aatggctttc tattcttcaa
    14221 tttcctccat ttttgcacaa tagacccatg ggatggggtt gctattggcg aatatggggg
    14281 agttttttaa ttctctctat atatactcac gacttcgccg atggtgcgta tatcgttgct
    14341 ttcgtctagt tgaatatcag cacattcagg gttaagactt tctaaatacc cttgacgcag
    14401 tttcttgacg tagttagcgc cgtctacttg gaagataccg atagtgttat agtcaacttg
    14461 aggtgtattc ttgataaata ggtagtcgcc attctttatc tttggctcca tagagttgcc
    14521 gacaacataa gcgatagcgt cgtagtcgtc tggtatttca tcagtataaa agcatttttc
    14581 catgtttagg ttatcgtctt gggttatccc gtttccggcg gttacaactc cgataacagg
    14641 gagcgtcttg ctttctctgt agtcgtccag actgataatg ttttctgata ctatgttttc
    14701 gtttttctgc tccagcagct gctttttaag ataagtcaag gctttttctt gtcttggtgg
    14761 agtgagttgg tcagctatga gcgtgatttt ttcaactgtt gaagttgatg gagaagagtt
    14821 ttcaacacct agcaggtatt ctactgatat acctaaaaca ttagcaaaat cttgagccct
    14881 gtttagtggg aattgtctgg ttttatttaa gtatctagac atggcagatt ttgccaaccc
    14941 tactcttcga gctaactcac taagagaaag gtcttgtttg tctttttcta agacgataat
    15001 atctataatt tcactattag agcgcatttt acacccccct ttcttaattt gattttatta
    15061 taccaccgtt cccaaaaaag tacaagaacc atgttaaaaa tatttttttg taaaaaaaat
    15121 caagttttgt gttgacaaat gggaacggaa gagttatact tgttttgttc tcttacggga
    15181 acgactaaaa aagaaaggtg gtagctgatg gaattaaacc taagacgaat taaagcggag
    15241 cgcattgcaa aaggctatac tcaagatgtg atagccgaaa aaatgggatg gaagtcccga
    15301 gcgccttacg caaaaagaga aaatggaatt gtaccatttg gagctgacga gcttgctgaa
    15361 tttggtaaaa ttctgggcta tggcgtaaat gaattgggaa ttttttttaa taaaaacgtt
    15421 cccgaataag aacggaagga gtaacccaat cgcaatacta tattacatct acaagatact
    15481 ccactggtgc tttagcactg gggattgata acaaaaaaag gagaaaagaa atgaacttta
    15541 aagaatttaa aacatggcta gatgatgccg tgagtatggc tgaagctatg gcattacctg
    15601 aaaatacagg ggtacttgac gacttgatag aaaatgcggc caataatctg gcttttatcg
    15661 ctgagttagt ggaaaaccgt caactgattt atagaaaacc tagacatgaa gattaaaaaa
    15721 gacaataaaa aaagtcactt gctgatagtt tagcgaccga ggcaagcgac aagatttagg
    15781 gtatagatat tttttctata tctcaattat aacaaaaata aactaatcaa tcaataacaa
    15841 ctaatagcag gcaagcaatt agaaaaggtt ttgaaaagca tagagcgcca actcttaaaa
    15901 ctggtacttt ctcacgcttt caatttggcg agtctgagcg tgaggctagc aattacaaga
    15961 aaaaaactgt ataagaaaca actcaaaaag acccacgctc agaaatttgg cgaccgagag
    16021 catgaggcat gcgacaggaa aaactgtata agaaacaacc attcaaaatc cccacactcg
    16081 ccatcgctca actttgagtg tgaggatatc ctggatagta aaaggcatta aaaagccctt
    16141 agggcaacta cacaacatag aaacagaggt aaaaatatgg aagaaacagc atacgagaat
    16201 ttaactagac gtatagacag aattagcgca gaaatgcgag aaattggcga aaaaactggg
    16261 cttagtagac tttcgttatt ggcaagtcag acagaattca tcaaagaaga attatcccgt
    16321 ttactttgga ttgaactccc tgaattgaat gacagccata aaatcgaagc ggtctctaaa
    16381 agcactacgg gaatcttttt ctcccctggt atttttgaaa tggacgctat gcgaaaagca
    16441 ttctttaaac gccaagctaa gcactttttt gacaacgaag cagaccaaca ggcgtatata
    16501 gaacatactg aaaaggagta tttaggggct actgtaacct taaaagatat tctttttaac
    16561 tctaaaaatg gaactcagaa agcaaataaa agttgtctta tagagaagtt tgaggaggca
    16621 atgcaatgac actagaccta ggcaaaatga cacaagcaga atttgataaa caaatggctg
    16681 aaatcaagga gagaaatcca aacatttttc aactgatttc tgatttttta gatagaaagg
    16741 taacacccga agaggtggac gactagttga atatggagcg agctgaacaa gtggaatata
    16801 ttaagaatta tcaagcgagg gcataacatg aatgaactag atataagtaa cacacaggct
    16861 gctgtcttaa tcgtgatttt gattggttta ctgctttatt taaaccaccg agaccgcaaa
    16921 aaaagcgccc aaattgagcg agaaaaccaa cagacgataa aaacacctag cgaggattta
    16981 aaccctgaat atgggcgata tatccagctt gcaggagtca acgtatgggg agggatggaa
    17041 tgagtctatc agagaatgat aaacgagtat taagattaat caaggtaggg gctgagaact
    17101 ccataacagg gtcagaaatt agcctgacaa ccaagctaac agaaagaaca gtacgtgaca
    17161 ttatcaagcg tctagtagtt aagcacaaca tccctattgt aggggttaga tgtggcgttt
    17221 ttagtgggta ctttatccca gcgaataaag gcgagttact agatggcgct aaggcttttt
    17281 acaaccaagt acaggaggag agcaagcgcc tagcggtgtt gatgaatagc gacctagaaa
    17341 gctacaaaga aaccttgaag gaggtgggcg gatatgttta gcttaagccg agaaagtgag
    17401 catgatttga cgcatggcat tctggaggta gtggaaagat acctggaagc gcgtgagaaa
    17461 gtaccgccaa gattgaccaa gttaataaat agagttgaac tcaaagaaga gttaaaaatt
    17521 agtgacaaca cgctgaataa gtgggaaagt cagggtttaa gacgctatca accaccggac
    17581 gatggtgcta gaataatatt ttatttagtg gatgacattc gtaggtttat gggggtggag
    17641 aatgggtaga tataacacac acccagcgca aggcggaggt cattatcatg acattaaatt
    17701 gtataagcac cgtggcagat ctttggaaca gttccaagaa caaaagctac tgaagaagtt
    17761 aaaaaaaaac gcaaaaaggg gcgatagtat gacaatttat gaggctagag gtttccagag
    17821 taatcttgtc tatccatttg ataagatgga gccgttccag tacattgaac gctttaagcc
    17881 tttggtagtc cctgaaagtg ctgatccgga ggaatacaaa agaacccagg cgccatattg
    17941 tttaagtggt aaggttatgc cggagaaaaa cgggagttac aaacgaaaca actccagtct
    18001 aatttatcgg gatttgattt tccttgatta tgacgatata caagggacga ccgaggactt
    18061 catagaagcc gtttctagcg ctttatttgg ctactcttat atcttatacc cgactatcaa
    18121 acatagcata gaaaagcccc gttttcgcct tgtggtgaaa tctaacaacg tgatgaacga
    18181 ggcaacctat aagcaggtag taaaagagat tgctgacaag attgggctac cctttgacat
    18241 ggccagttta acctggtcac aactccaagg gctaccagta acaacaggcg acccagcaac
    18301 ttatcaaaag attgtagagc atggacttga ttatccagtc cccaaggttg aaccaagagc
    18361 gaagcaagga actactgagc tttacaagcc tagagcaagc ggtcagaggt caatgactat
    18421 gaggatcatt gacacgcttt tcaacggatt tggagacgaa ggagggcgca acgtagcgct
    18481 gacacgcttt gtgggattac tcttcaataa gtgggttgat tgtgacctag agaccgccta
    18541 tgaactgaca aagatagcaa atagcgtgac agttgaacca ttgcctattg aagagctaga
    18601 ccgcactttt agcagtatag cacgggctga gtatagaaag agaggttaga accatagaac
    18661 tagaagaatt agcaaaccta aaaagtgaaa tcttggaggt cagagagcaa gaacaacctc
    18721 ctagaacgat gtgggaactt tatagtagga tttgggagct tggggatcaa tggcgtaagg
    18781 aaaactccta tatcgtcaat gaaggaaaga aaaacgaaag ggtagaaatc ccacgaccaa
    18841 gtgttgcaat cgtagccaaa gcgttacagg aaatttgcca ttttaccttt ataggtgagg
    18901 gggttataag tgatattagt aagttatatc tttaccattt ggatttaggc cattatgtat
    18961 caagtaacga cattttccga aaattgcttt taaaatatga ctcacgtttg acttctaaca
    19021 agttcttttt agaacttatc tcctatatcc gtacagaaac taagatgaaa ccaccgctgg
    19081 acgattatcg atatattcca gtagcgaatg gagtttataa tattaaaact cataaactag
    19141 aggaatttag tcctaatttt gtcattacca gtaagataca aacggaatac aatccatgcg
    19201 ccagaaagcc tattttagat ggttggtttg attttgatag atggttagag gctttagcag
    19261 ttaacgataa agaagttgta gctttattgt ggcaagtcat aaatgaggct atcaatccca
    19321 accgaacacg taagaaaatg gtgctaatgg ttggagatgg taataatgga aagggtactt
    19381 ttcaagcctt gctggagaat ttaataggac ggtcaaatat tagtaatttg aaacctgacc
    19441 agtttgggaa agagttctat ttaggcgctt tggaaggaaa ggtttgtaat attggagatg
    19501 atatttctaa caagtacctg gatgaagttt ctgaccttat gagtgtaatt agtggagatc
    19561 cagtgcaggt caataaaaaa agcttacaac ccgtggaagc acgtttcaga ctattgtgta
    19621 tcttttcggg caatgatttg cctagagcta gaaataagac catggggtgg tatagacggc
    19681 tttgtatcat tcctttccgt gcagatttta acggtcagaa agaacgtcat gaaatcaaag
    19741 accgatttat aaagaacaaa gagctgctag agtgggtttt gtttaaagtt ttaaatatgc
    19801 cagattttga tagctttata gaacctgaag cggtacaaaa aatgcttagc aagtacaaaa
    19861 acgataacga ttatatcaaa gtttgggtag agaatttcta cataccaaac gggtggcatg
    19921 aaataaacca tgttccaatg tttattgcaa gaaataaatt aaaagagttt gctgaggata
    19981 taggtataga taaacctaaa cttggacaat ttagcaatgc agtaatggcc gaattggaaa
    20041 aaacaacgtc atataagtac tcagccaaaa acggaacggt tagctctaag ttttatgacg
    20101 tacttgaccc acaaggtttt caacgtaaaa gatttgttaa aggtatatgg ggaatacact
    20161 tagaagatga agatttaggt taggaaattt aatactaaaa aaccaattac accaagggtt
    20221 atagcaattt aggttatgca aaaaatagaa acataaccta aacactaacc tttgtaaacg
    20281 ttgatataaa agtctttgcg agtatttagg ttagtaggtt agtttttatt tctaatatct
    20341 ctatataaaa aataatatat atacgtgtta tataggcgcg aacttaaaaa gtaaaactaa
    20401 ccctaatcta acacccttga aacgttgata tagtaggctt ttgaagggtt attttttaaa
    20461 actaatcaaa acctaatcta agagaaaaaa ggagcaaacc agatggcgat gaacatttgt
    20521 caaagagtga ctagactaga agaaaccgtt tagcggatca gtgaggtgct aggtggcttg
    20581 attgaaaatg cgagctgtaa cgctatagta aacaataaaa acatcgaacg gattcaggaa
    20641 ggttttgaaa tagtctttaa agagcttgat gaactaaaaa cagtacctga taaacactaa
    20701 aacatttaaa caaaatgggg tagatagtac cgaccccctt gcaatggtgt aactactagt
    20761 gacaccctaa aaacagaaag aggaaaaaca acatgaaaat taaactattt tatcagaaat
    20821 acaagcaagc cctttgggat ttggaaagcc aggtaaatgg ttttatggca gacgttgaag
    20881 ttattgacgt gaaatataca aaggcaacag tggggaatag tgaggatatg gatacactaa
    20941 ccagtgtgat ggttctatac aaataacatg aaaggctaaa atatggagat acaagaaggc
    21001 tttatttatt ttagaaatta tggtataata aaactgttag aggttccaag gtttgggagt
    21061 atcacgctta aaatacaaga cggtgagatt gtctccagcg tggaatctaa aacaacaata
    21121 tttaaaaaga atactgactg aaaaaatcag aggtatagca taaagtagag taatctattt
    21181 tggctatgcc tcttttgttt ttggaaagat tggaggaaaa agaaatgcca acattgcaag
    21241 aagtcaaaaa ccagatggac aaagtacgga ctcaattaga gatttttgat cgctttgatg
    21301 aggaaatcaa gaaagcagag caagaagtta aggctattaa agctaagaaa gcggacttac
    21361 aaacttttga agattttcaa gctataaacg caaaagaaaa gtatattgct gatatgaaag
    21421 cacaaagaac taaactcgaa aaagaacgaa ttgactcaat cgtggcagac gctagaaaaa
    21481 tcaatgcctc aggttattta gaaacagcat tagagcaaga tgaaacagtg aaacgccaac
    21541 gtcaagaaat caaacagaaa tctattgagc ttctggagtt gattgcaaat tataacgaaa
    21601 actacaaaaa tactgctaaa agattggcgg atgaggtaag agaaacaggt atcgaagagt
    21661 tatttgaccg cctgaatacg tcaccagaat atagtggagt aagtaagcct tacatttaca
    21721 gtggtgtagc tggttatatg ggaaaccaac accgctattt agatccgagt gatgatttag
    21781 cgtattttgt gaatcgtatc aatttatttg aaggagaaca ataatgaaag atgaacataa
    21841 acaactattt caagaaatcg aagaagagaa gagacaagct gacttactgc aagggcttgc
    21901 caagaacgta gaaagtattt caaaatctta tgaagaggaa gctgtgaccc ttgaagagtt
    21961 taaagctatg ggctacaagc gtagacatga actatttgag aaagataaag ccctgtatga
    22021 taagctacta ggcaaggaaa aacgcggttt gtaatgtgga ggggagcaat cccctttttt
    22081 tacataaatc agacagaatt acacacgagg taggggaatg gttagaagtt caaaagcaag
    22141 actagaaaag ttagaagagt atgctggaaa gacggaatat gcaacaactg atgaatgtat
    22201 atctttatat gtggattgtt taagatttgc ttttcagcaa gatgaaataa agatagatat
    22261 ggatgatttt attaaaacac catttaaaga tattaagcta gcagactata agaaatcaaa
    22321 aaaacgtatg gatgaactta aggaaatgac tgggataagt gagtttccag aattagagca
    22381 ataaagcgag gtgaacagta tttgacagaa ttaagcagaa aaaaagaaat atttatggcc
    22441 aattatctca tgactgggaa tgtaaaaaaa gctagtgaat taagtgagat caccagaaag
    22501 acggcttaca attacttgaa cgatgcaacc tttaagagaa tttaccgtga aagacggagc
    22561 gaacaactta aggagtctac tacgctgtta cagaatgcaa gcgttgaggc agtcaatgta
    22621 ttaagggaaa tcatgcttga taagacagtg agcccgtatg cgagacaaca aagcgcccaa
    22681 agcattctaa acatggctta taaggcggtt gaaatggttg aggtagtgga gcaattagaa
    22741 atattagagg cgaagatact agatgaaggc gattaaaaac cgtttaaata agttgaataa
    22801 gttatcggtg gttgatgaag ttgataccgt gtttttgacg cagattgata ctggacattt
    22861 tgaggtaaga tataggatag gtggaaaaaa tcccaaagat attatagaag tctatccgac
    22921 aaaagaagaa gcagaaaaag atatttcaga aattagaaat acaaaaggat tgcggatatt
    22981 ctgggacaat ttggctttat tggaggatga ttagagctta tcatttatca agcagataag
    23041 agcaataaaa accctcctta actccctgag aaacgacaag cagataagcg aagtttttag
    23101 ccctcttatt tcggatttac tccttgcaga atgacaagga aataagggag ataaaaacat
    23161 cccttaattg cttatcaaac cacaaggaga tacgggggct atctccctcc ccacgcactt
    23221 ctatgagctt cacaccgtca ttgtacattt tttctcacgg ggaagcattt gaagctagag
    23281 cgaacataga gaaaacgaaa aaaagccaag gcactccgcc tcagctataa tctcaataat
    23341 attattatac cacaaaggag agcaaggcat gacaccagag caggtaaaag aaaaactaga
    23401 gggcgttaag tggataaaca aggagatcaa aggattatat ttggaattgg aagtcctgga
    23461 gagtggtatt atcaaaaagc caacactaag ccatagcagg gtgcagacaa gcagagagaa
    23521 caagacagag aacaatctta taagtgttct gaagctaaaa gaggatacac tccagagaat
    23581 tgagcgcctt accgaggaaa gaatggcaat atctgagcta atcgataaac tggccaatcc
    23641 gcttgagcgt tctgttctaa gactttttta cttgaatgat cttgtagctt cggaggtggc
    23701 tgaagaaata gatagatcaa atactacagt atatcgaata aagcaggaag ctatagaaca
    23761 cttaacaggt attgtaaacg gggattgatt taaccttacc acggaattag gagagtatgg
    23821 ggaactctaa gccccatatt tgaccctatt tcgcttggtt ttgtaccgga cgattaaaac
    23881 accatggata aactagaagc ccttagaaac gaatcagggg gacttttgtg aggtcataat
    23941 cttataaacc acgcgcttca tggtataata tacctatcag caaccagcaa taaaaaaagc
    24001 acgtttgacc gtgctagttt cttgcctgct gaactcgtca tttattgccc ttttgtgggg
    24061 ctttttttgt ggactttttg agaattttta agaactttta atgatttcta atcaaatgag
    24121 atttttcaaa aagtcagtaa tatcaagggt ttaggcgcta taaacaagtt taaaagcgtg
    24181 tagattacaa tctaacacaa aaagggataa agtgctaacc ctctaactaa gggttctcag
    24241 tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac aacatgctca
    24301 caattactgc attttatttt gatatctgct cctacacgtg taatttccca acgattagcc
    24361 tttttaccag tcgacttgat tgtacaagcg tgtgattttt tcatctcaac aaaatttcca
    24421 acttgataca tactactctc cttttctttt tcgattatat cataaaagag gcgagccagg
    24481 ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga agtcttcgtc
    24541 agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa tggtcacctt
    24601 ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac taatggtcaa
    24661 atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa cttctggaga
    24721 gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac cattttgagt
    24781 cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca cattaaaagt
    24841 aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt ttccttctag
    24901 gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat tggcaaagaa
    24961 aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta gagaacggct
    25021 aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt tctggcttag
    25081 gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata cgaagtggac
    25141 acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt cattaataat
    25201 tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt cttggattcg
    25261 tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac tggttaaaac
    25321 aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac tagatactac
    25381 attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatta acaaaccagc
    25441 atcttcattt ttttgagaaa taaaattttc aattgaaatt tgaccatttg aaccaattaa
    25501 agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa tggcattttt
    25561 agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt tattaattga
    25621 aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa tagtaataat
    25681 agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt catatcaagt tttttagctt
    25741 gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa ttatttgatt
    25801 ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat caaagatttt
    25861 attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc cttcccaatt
    25921 tttggaagac tattatctgt tagttctcta gataaataca tggctacttg acgggccaaa
    25981 acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc ataaaagtta
    26041 ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac atcttgtttg
    26101 cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt ttttactctg
    26161 gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga atcaaattgc
    26221 ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc cgtcttactt
    26281 tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt caatccccaa
    26341 ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact acgatcactc
    26401 gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa aaattcttcc
    26461 tgagttgcga ctttttttcc gctgagtgac tgtatatcat cgattaacaa aagatcaaga
    26521 ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc aagaaagtca
    26581 ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt ttttagaatt
    26641 tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc atagataaaa
    26701 agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga tacagcccaa
    26761 acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa tcccgtatct
    26821 gaataaggaa tagatactaa ctttggacta tagtcataaa gagttaaatt tgtagcttct
    26881 tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg agttatttca
    26941 gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt ttcccagacc
    27001 atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac cttgatgagt
    27061 tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg tgcaaattct
    27121 aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac tatttaaaag
    27181 tttaatacta gagatatttt accatagata gcaagaattt tccacaagct gtgaaaaata
    27241 atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa ttattgattt
    27301 attaagcttt ttatcgaaaa acatagtgga taaccttgtg agataaaaaa ataaaagaac
    27361 agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa aaagaaataa
    27421 tgatttttcc actgtctttt ttagatagtt taatttctac atctaaaccg agtagttttc
    27481 ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc ttttgttttt
    27541 tctctgtcag aagagtttct aacttcctta cagaaatatc ttcttctata atccgttgaa
    27601 agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg gcttgtgata
    27661 gtttgccatt ttctacttct gagagaatct gttctggcaa ggaaagtaaa cgaatggagt
    27721 tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg gtgaatcctt
    27781 tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt tctctctgta
    27841 aattttcaat aatggactgg accatcatct cttggtctga aatctgttta acaacagctg
    27901 ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct gcaaggattt
    27961 cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca ttttctttga
    28021 tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt tgatagggat
    28081 ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta cactaacaca
    28141 tcttttctct tatgtaaagc tttctttaca tagatgtcaa tcaagattct aaatcacctg
    28201 aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag taggttatct
    28261 taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt gatgaagcaa
    28321 tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca ttggcaggca
    28381 tattactttg taccgaacga acaactacac cagatgtaac attacttgga atattgagtc
    28441 ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc aaagctggac
    28501 gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca tttgcaggaa
    28561 ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta cttgaggtaa
    28621 ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct gggttaatag
    28681 cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat cttaaggata
    28741 catttctatt gagactggat acgatacctt gagtgacagt atttgcatat tcagaaccta
    28801 acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa tcaccaaact
    28861 cagctactgt tgtcactttt tctgaagaga ttttgacgac agcaatatca gagaaagtgt
    28921 cagctccgac aatttctcca ggtactttag tcccatctga caatctaata tctactttgc
    28981 tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca ttctttttat
    29041 aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta tcatcattgc
    29101 caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca gcatctttta
    29161 ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt gtaatagtac
    29221 tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt gaaaaactac
    29281 ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac cattttttgt
    29341 aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga aagtataaac
    29401 tgactagctt aattataact taaacacaaa agttttacac aaactgtgga taactctttt
    29461 gaaactgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga tgtgaaaaaa
    29521 tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg gaaactgaaa
    29581 gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag atttgctaag
    29641 tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga atcagaaaat
    29701 caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga ccgtgatttc
    29761 gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag taagcagtta
    29821 gaagaaactt ctataaaagg attttctact cttactttta ttattggggg aagtttagga
    29881 ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg cctaacctta
    29941 ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt tacgattcag
    30001 cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg gtagaataat
    30061 tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga acggtcgcag
    30121 gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg gcttttttct
    30181 taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc taaaacgaaa
    30241 ttccattttg tataatgttt tttgtaagtt agcttacaag aaaaaacatt ttaggagatt
    30301 ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa aaagacttac
    30361 aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt attttacaaa
    30421 gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg ggacggttat
    30481 tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc aaataaatag
    30541 aaaagaatta ttcgtttttg gtgcttatac attactaaca gaaatagtat ttgattttcc
    30601 cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc ctttgggatt
    30661 atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat tcctaagttt
    30721 actactatct cttttatatg agagcactca taactttctg tccgtaactt tctcctctat
    30781 aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg tgacggtgtt
    30841 aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag cctattttga
    30901 cgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat tgctacatat
    30961 tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt ttggaagtat
    31021 tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga attctcataa
    31081 agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga aacatttaca
    31141 gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc gacatgatta
    31201 tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac aggaaattga
    31261 cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag ataagtacac
    31321 ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg ctcagtcaat
    31381 tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata cgattaccaa
    31441 gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga ataatgctgt
    31501 cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta agatggaaac
    31561 tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt caggagatct
    31621 atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa ataatgtgaa
    31681 agaactacta gataagtaca acaatattat tttagaaaca gagatggaag gcagtacatt
    31741 tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt agaagatgtt
    31801 attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga atcgaatatt
    31861 ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat tgaaaatgat
    31921 gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa aaagggattt
    31981 gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt tatcactagt
    32041 cgatcagagt ttgcgactct aacctataaa tatcaggtat cagccctaga ttttgttgat
    32101 aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt ctacacgaag
    32161 agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta caagggaaat
    32221 gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt atctcataaa
    32281 ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac agatattcag
    32341 gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt ggtaaatata
    32401 ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga agaccatcgt
    32461 tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa aaaatctcaa
    32521 aagtgattga caattagcaa gaaattgata taatggttat atctgctaca gatagaaggt
    32581 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
    32641 tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat
    32701 gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc tgtgttcctc
    32761 tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat ttcttgagaa
    32821 ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc atgagttaga
    32881 tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa tcgcttttgt
    32941 aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat ttctttagtc
    33001 ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc aaaaacttct
    33061 aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa tgtatggaat
    33121 agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt atagaagctg
    33181 gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc aaatggctgt
    33241 tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa gcgtttgtta
    33301 ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa atagattttt
    33361 tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt agacaatatg
    33421 tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa ttttaaaaaa aaccaacctt
    33481 tattattgtc atgatcggga tttctcttat tccagatctg tacaatatca tatttttgtc
    33541 atcaatgtgg gatccatatg ggcaattgtc tgacttacct gtggcagttg taaataatga
    33601 taaagaggct tcctataatg gtaatactat ggcaatagga aaagacatgg tgtccaattt
    33661 aaaagaaaat aaaaccttgg attttcattt tgtagatgaa gaggaaggaa agaagggatt
    33721 ggaagatggc gattactata tggtagtgac tttaccaagt gatttatctg aaaaaacaac
    33781 tacattatcc aatattcaat cgacagcagc ttatcaatca ttgacaagtg agcaacaaac
    33841 tgagataagt gattctgtat ctcaaaattt aactgctagt attcaatcgg ctcagtcaat
    33901 tgtagcttta gtacaagatt tacagggaag tttagaaaac ttacaaaatc aatcttctaa
    33961 tctttcgact ttaaaaaatc aatctaatca agtatcacct attacttcta cttctttgat
    34021 aggattgtca agtggattaa cagagataca aggagatgtt actagcaaat tagttcctgc
    34081 cagtcagtcg attgcatcag gtgtaaacgc atatactaca ggtgttgata aagtttctca
    34141 ggacgtcatc cagagagccg ttgggcttgg ttgaaatctc gagctgaaat aaatggtatt
    34201 atagctgttt tggcaggaat tttggtatat ggaggagttc atcttattgg tttaactgct
    34261 aatcatgaga tgagaatatt tattctcatc atcctaacaa gtttagtatt catgtctatg
    34321 gtgaccactt taacaacgtg gaatagccgt ataggagctt tcttctcact tattttgctt
    34381 ttactacagt tagcatcaag tgcaggtact tatccacttg ctttgacaaa tgatttcttt
    34441 agatctatta atccctggtt accaatgagc tattcagttt cgggattacg acaaacaatc
    34501 tccatcaaca agtcattttc ctagctgtca tactagctct atttactggt ttaggtatgc
    34561 tagcctatca acataagaaa atggaagaag attaaaaaaa tcgaccgatt aactggtcga
    34621 ttttttatgc cttagatgac tttcgtctgt gattatagat tccaaatagt aagagagaag
    34681 taaaggaaca gattgctcca gtaataaaac cattgggaat gaaggaaagt gtaatagttc
    34741 ctttcccctt gggaatgtca actttcataa atccagtttg agcttgttta atttctattt
    34801 tcttaccatc ttggtaggca gaccaacctt tgtcataagg aatggtgaag aaaatagatg
    34861 tatcttgttg gacatcatat gtagcaaaaa ccttgttttt agaagttgat actgtgacag
    34921 gttgttcttt aattttttga attgcctcgg tgaaagtttt ggtatctaaa cgatagaagg
    34981 taggagattc aaatgatact tgtgaatttc cagggaaact aacattgata ttgaaagttt
    35041 ttttctcttt agtatatcct agattaaaga aggagaagac attatcagtt gtaaaagtct
    35101 ttttttcacc atttacaagg atgtcaacct tcttttgttt atcgttagaa aagtgaaggt
    35161 ttatgaaaga gagataaact tggctgtttt ctggaacttc aatttgatac tggattgctg
    35221 catcttcatt tgaagaactt gtgacactaa tcaaatcatt agtattttct attttttctg
    35281 ttttttcata agatattgga gaaaaataat caaaattgac gttagcaagt tgatttaaaa
    35341 atgaggcctg attatccaag gtatgttcat tgaacttgac atcattgtaa acagattgac
    35401 tagcaactgc aatcggaaga gagtattgat tttcatatag ggtaagatta tctttttgat
    35461 agatatcttt aaaaccatac ttatcaatag gactgtctga gatattgtac tggataccaa
    35521 ataaactatc agccaaaata ctattatttg catatcggag attgagatta gtcccagagg
    35581 atttaaaacc aagtttatct aaagtagagc ttgatgaacg atttcgaaca gatgaaaatt
    35641 gagagattcc attgtagttg aatttcatac tgtcatttcc tgtctgagtt tgtagttttt
    35701 cagtacgagt aaattgattt ccaatatatg ttgagaaaga ttccatagct gggatatctc
    35761 gactataagc acttcgagaa gcaaatcccc attccttagc aattccgtcc atttgagatg
    35821 aagcatttaa actcatttca accagtataa ataaagagat tagaatggca aatagattca
    35881 cagatataaa ctttttgata actgcaagga gtaaaagaga atagacaacc aaaaattcaa
    35941 gagtaagcag aatattcaaa tctgttaaaa aagaataatg cgattttaga tagatggtag
    36001 ctaaaaatcc tgctactaca agaaaaagcg aaactaaaaa attccagact ttaagttctt
    36061 tcagacgctt taagacttct gctgctgtgt aaattaacaa ggtagagaaa atccaagcat
    36121 agcgatgtaa aaacatgttt ggagtatgca tgccttgcca aaataagtca agagcttcta
    36181 tgtaaaagct tgcaattaga aatgcaaaga atattacata tatgagtttc acgtgaaact
    36241 taatagattt cagcgtaaaa aataaaatgg tcaaaataaa gggaagtagt ccaacaaaaa
    36301 tcattgggat ggccccatac tttgttgtgt caaaggaacc aatgaattgc ttagcaaaga
    36361 gatcaagata ccagctactt tcagtttgaa actttgtaac ttcagtcaat ttttccccat
    36421 gtgtctgtaa atcaaataga gtgggaagag tcataatcaa actagccata ccagctaaaa
    36481 aggagataac tatgaaatca agaacagatg attttcgagt cttaaagtcc cacgaaattt
    36541 gacagagata ccagaaaata agaaacaata ctgtcatata tccaaaataa taattttgaa
    36601 taaataagat tgacagactt gtaaagtaca ataggagttt cttttcagtt atcagtagat
    36661 gtaaaccagt tataattaaa ggaatcaaga taaaaacatc tagccaggtt tttatctcta
    36721 attgactgac agtgaaactc atcagagcat aggaagtaga taaggctagt tttaaagtct
    36781 gagggataga ttgaaacaat ttattcaaac taaaaaaggt tgacagacca atcaatccaa
    36841 attttaagag agtggtcaga tagacagcat ctggcatatt cgttagatca aaaaagtaaa
    36901 ctagaggcgc gagaaaacta cccaagtaat aactagatag ggcatagaag tttagcccta
    36961 gaccacttgt aaaggtgtaa aacagactac tatttccatg taggatattt cgtaaggcta
    37021 catcaaaaat aacgtattga tgaaagccat ctcctaatag aggagagttg tcgctattcc
    37081 agtagatacc ttgagataga tatactccag acataatcac tacaggaatg atgaaagaaa
    37141 taaaataggt tcgatatgtt tttaaaaatg atttcatgtt acctcgtaga atgatagaaa
    37201 actcagttgg ttaacccaac tgagttttga agttttattt agtctttcca aagttcttta
    37261 acttttgctt gtacttctgc attttctagg aattcatcgt aggtttcatc gatacggtca
    37321 atgacgccat ttttagataa gacaatgata tggttagcca aagtttgaat aaactcgtgg
    37381 tcatggctgg caaagatgat tgattcttta aagtttttca atccatcatt caagcttgag
    37441 atagattcca agtccaagtg atttgttgga tcatcaagta caaggacatt tgattttaag
    37501 agcatgagtt ttgaaagcat gacacgaact ttttctcccc ctgacaagac atttacaggt
    37561 ttgttaactt catctccaga gaagagcata cggccgagga aaccacgtag gaaagtattg
    37621 tcatcatctt ctttacttgc gaattgacgc aaccagtcaa gaattgattc tcctcctgca
    37681 aaatcagctg agttatcttt tggtaggtaa gattgactag ttgtaactcc ccacttgaca
    37741 gttccttcat agtcaatatc tcccatgatt gcacgaatta atgcagtcgt ttgaatatca
    37801 ttttgtccaa taagtgctgt cttatcatct ggacgcaaga tgaaactaat attatccaag
    37861 atagtttcac catcaatctt tacagttaga ttttctactg tcaagagatc attaccaatc
    37921 tcacgttccg ctttaaagtt gataaatgga tatttacgac tagatggtac aatctcttct
    37981 agctcaatct tatcaagcat tttcttacgt gatgttgcct gccttgactt agaagcattg
    38041 gcagagaaac gagcaacgaa ttcttgcaat tgtttaattt tttcttctgc tttagcatta
    38101 cggtctgcta gcaatttagc agcaagctca gaagattcct tccagaagtc gtagtttccg
    38161 acatagagtt tgatttttcc aaagtcaagg tcggccatgt gagtacaaac tttgtttaag
    38221 aagtgacggt cgtgggatac tacgataact gtgttatcaa agtcaatcaa gaagtcttct
    38281 aaccaagtaa tcgattggat atccaaaccg ttagtaggct cgtccaagag aagaacatct
    38341 ggtttaccaa aaagtgcttt ggcgaggaga acctttactt tttcaccgtt ggccaattcg
    38401 ctcatgtttt ggtagtgtaa ttcttctgga atgtttaggt tttgaagtag ttgagaggct
    38461 tcactctctg cttcccaacc tccaagttcg gcaaactctc cttcgagttc ggcagcacga
    38521 accccgtcct cgtctgagaa atcttccttc atgtagatag catctttctc tttcatgatg
    38581 ctataaagtt tttcatttcc catgataacg acatcaatgg cacgttcatc ttcgtagtca
    38641 aagtgatttt gacgaagaac agagagacgt tcatctggac caagagagat gtgaccagta
    38701 gtaggttcga tatctccagc taaaattttt aaaaaggttg attttccggc accattagca
    38761 ccgattaatc cgtaagtatt tccttctgta aatttgatat tgacatcatc aaaaagtttg
    38821 cgatcactaa aacgtagtga aacatcagat actgtaagca atgtttttct cctatatgtg
    38881 taatatattt attctactag aaaatacaga aatattcaaa tttttatttg tcaattttgt
    38941 gtaaattata tttacagtat cctttacaca aatctgtaaa aagcaaggct gatttatttt
    39001 gataaattac ggttatttca ttaaaaaaat gctataattg aaaggactat atcgaaggag
    39061 aacaaaatga ctaaacccat tattttaaca ggagaccgtc caacaggaaa attgcatatt
    39121 ggacattatg ttggaagtct caaaaatcga gtattattac aggaagagga taagtatgat
    39181 atgtttgtgt tcttggctga ccaacaagcc ttgacagatc atgccaaaga tcctcaaacc
    39241 attgtagagt ctatcggaaa tgtggctttg gattatcttg cagttggatt ggatccaaat
    39301 aagtcaacta tttttattca aagccagatt ccagagttgg ctgagttgtc tatgtattat
    39361 atgaatctag tttcgttagc acgtttggag cgaaatccaa cagtcaagac agagatttct
    39421 cagaaaggat ttggagaaag cattccgaca ggattcttgg tctatccaat cgctcaagca
    39481 gctgatatca cagctttcaa ggctaattat gttcctgttg ggacagatca gaaaccaatg
    39541 attgagcaaa ctcgtgaaat tgttcgttct tttaacaatg catataactg tgatgtcttg
    39601 gtagagccgg aaggtattta tccagaaaat gagagagcag ggcgtttgcc tggtttagat
    39661 ggaaatgcta aaatgtctaa atcactaaat aatggtattt atttagctga tgatgcggat
    39721 actttgcgta aaaaagtaat gagtatgtat acagatccag atcatatccg cgttgaggat
    39781 ccaggtaaga ttgagggaaa tatggttttc cattatctag atgtttttgg tcgtccagaa
    39841 gatgctcaag aaattgctga tatgaaagaa cgttatcaac gaggtggtct tggtgatgtg
    39901 aagaccaagc gttatctact tgaaatatta gaacgtgaac tgggtcctat tcgtgagcgc
    39961 cgtattgaat ttgctaagga tatgggagaa gtttataata tgattcaaaa aggtagtgaa
    40021 agagcgcgtg aagttgcggg tcaaacccta tctgaggtaa aaggggcaat gggacttcat
    40081 tactttaact aagtttattt tacaagaaac tatcatttct atctcgaaga aaagatagtt
    40141 ttttatttac ccctgtaaca tttgacaaat ttttatagaa tggtatgata gatacaatat
    40201 aaaaagagtc aagctcaaaa agaaagaaaa gaggaaactt cgaatgtcta attgggacac
    40261 taaatttttg aaaaaaggtt ttacctttga tgatgtattg cttattccag ctgaaagtca
    40321 tgtgttgcct aacgatgcag atttaacaac taaattggca gataatttga ctttaaatat
    40381 cccaattatt accgctgcca tggacacagt tacagagagt caaatggcca ttgctattgc
    40441 tcgtgcaggt ggtctcggag ttatccataa aaacatgtca attgctcaac aagcagacga
    40501 ggttcgtaag gtaaaacgtt ctgaaaatgg agttattatt gatccgttct tcttgacgcc
    40561 tgaacataca attgctgaag cagatgagct tatgggtcgt taccgcatca gtggtgttcc
    40621 agttgttgaa acacttgaaa atcgtaaatt ggttggtatt ttgacaaacc gagatcttcg
    40681 ttttatttca gattataatc aaccaatttc aaaccatatg actagtgaaa atcttgttac
    40741 tgctcctgtg ggtacggatc ttgcaacggc tgagagtatt cttcaagagc atcgtattga
    40801 aaaacttccg ttggtcgatg aagaaggcag tctttctggt ttgatcacta tcaaagatat
    40861 tgaaaaagtt attgagtttc caaatgcggc taaagatgag tttggtcgtc ttctagttgc
    40921 aggtgcagta ggtgttactt cagatacatt tgaacgtgca gaggctcttt ttgaggcagg
    40981 agcggatgcg attgttattg atactgcaca tggtcattct gcaggtgtct tgcgtaaaat
    41041 tgccgagatt cgtgctcatt tcccagatcg gactttgatt gctggaaata ttgctactgc
    41101 tgaaggtgca cgtgcccttt atgaagcggg tgtagacgtt gttaaggttg gtattggacc
    41161 aggttctatc tgtactactc gtgtgattgc tggtgttggt gttccgcaag taacagctat
    41221 ctacgatgct gcagctgttg cgcgcgaata tggtaaaacg attattgctg acggtgggat
    41281 caagtattct ggagatattg taaaagcact tgctgcaggt ggaaatgctg ttatgcttgg
    41341 atctatgttt gctggaactg atgaagctcc aggcgaaact gaaatcttcc aaggacgtaa
    41401 attcaagact taccgtggta tgggatcaat tgctgctatg aagaaaggtt caagcgaccg
    41461 ttatttccaa ggttctgtca atgaagcaaa caagctcgtt ccagaaggaa ttgaaggtcg
    41521 tgttgcttat aaaggagcgg cagctgatat tgttttccaa atgattggtg gtattcgctc
    41581 tggtatgggt tactgtggtg cagctaacct taaagaacta cacgataatg ctcaatttat
    41641 tgaaatgtct ggtgctggtt tgaaagaaag ccatcctcat gatgtgcaaa ttactaatga
    41701 ggcaccaaat tattctatgt aaaaaacaat gaaaagaact ccagtgaaaa caggagttct
    41761 tttacaatgt tgtcaatttc tatttacagc agctttacca tcctgaatag tgaagatact
    41821 tagattttct ggcagatttt gaagatggtc taagcttgtt gttgtgataa aggtttggat
    41881 tgattgagaa atcgtttcta ataattttaa ctgtctagtg ttgtcaagtt cactcatcac
    41941 atcgtcaagc agtaatatcg gagattctgt ggtaatgctt tccattaatt cgatttctgc
    42001 taattttatc gagaggacga gactacgatg ttgaccttgg cttccgaaac tagcatccat
    42061 cccatttata taaaaagaaa tgtcatctcg atgaggaccg acaccagtat tctttttaaa
    42121 taaatctctg gatctacttt tttctaaagc aattttgaaa gattcggata agttttgttt
    42181 gtcagttata ttgacagaag attgatagga tattgacaac tcttcgatct gattagagag
    42241 ttcaaaatgt ttcttacgcc caaatgattc tagttttttt atgaaatcta agcggtgatt
    42301 cattacacga catccataat caactagctg atcatctaac acagaaagga atgtttcatc
    42361 tattttttga gctgatttta ggtaagtgtt tctttgcttt aggatgtggt tataattggt
    42421 taagtcagat aaatagattg gcttaatttg cccaagttcc atatcaatga attttcgtcg
    42481 aatcgaaggt gctcctttaa ttagttgtaa atcttcagga gcaaataaga caacattcat
    42541 gtgtcctaca taatctgaaa ggcgtgcctg ttttaagtga ttaacttttg ttacacggcc
    42601 tttttgtgtt agttcgattt ctaggggaat ggatccagtt tttttctgaa cgagacctga
    42661 aagatgaagt tgttcctcat caaaatgaat gagattttta tctgttcgag ttcgatgact
    42721 acgcgttaag gctaaaaaat agatagcctc taacatgttt gtttttcctt gtgcattacg
    42781 tcccaaaaag acattcaatt taggattaaa gtctattttc gtttctttgt aattacgaaa
    42841 agtcttgaga gatagatgtt gtagccacat gattatctac cagggaatcg tggagcttgt
    42901 tggcttttag gtgatgaagc aggtttcgat ttgtcttttt taactccctt attcatcttt
    42961 ttgacaagtt tagcgatccg ttctttttca actttatcag cttggtattc atcttgttct
    43021 tcagaagtag gttgtgtcaa caagatgtca atgttcatgt cagggatgtc aactttatcg
    43081 ccaatacgaa gtttttttcc acgacgactc tctaattccc tattaaagta aacagaatgt
    43141 tcagagagaa atgatttaat agctcctccg ctatgtgtaa ttccaagttc tttgagtagt
    43201 gcttggaggg taataaattc ttcaaataat ttgtattcca taattcacct caatctttgg
    43261 tattatacca tattttccta aaaatagtga gagagacagc gagaaatgta agcgattttt
    43321 atttcaaaag tgttacaggg aacaagaaaa tttcaggttt tcgtgatata atagaagtct
    43381 gtatataagg aggtaaatca tggagttagt gcatggaatt tcaacacatt ttatccaatc
    43441 aaaaaagttt aaaacaaaca aaattaccgt gcgttttacc gctccattat cccttgatac
    43501 gattgcaggt cacatgttga gtgcaagtat gctagagact gctaatcaga tgtaccccac
    43561 ttctcaagat ttgaggagac acttggccag tctatacggt acagatatgt caaccaattg
    43621 tttcagaaga gggcaaagcc acattataga attgacattt acctatgttc gtgatgagtt
    43681 tttaagtagg aaaaacgtgc taacctctca gattttggaa cttgtaaaag aaactctttt
    43741 ttcacccgta gtagttgata atgggtttga tccggcctta tttgaaattg agaaaaaaca
    43801 attgctagca agtttagcag ctgatatgga tgattctttt tattttgcac ataaagaatt
    43861 ggataaattg ttttttcatg atgaacgtct tcaattggaa tatagtgatt tacgaaatcg
    43921 tattttagct gaaactccac aaagttctta ttcttgtttc caagaatttt tagccaatga
    43981 tcgaatagat ttctttttcc taggtgattt taatgaggtt gaaattcaaa atgtattaga
    44041 atcatttggc tttaaaggtc gaaaaggaga tgtgaaggtt cagtattgtc aaccttattc
    44101 taatatcctt caggaaggta tggttcggaa aaatgtggga caatctattt tggaattagg
    44161 ttatcattac cgttctaaat atggtgatga gcaacattta cccatgattg taatgaatgg
    44221 tttacttggt ggatttgctc actctaagct ctttacaaat gtccgtgaaa atgctggatt
    44281 agcttatacc atttcaagtg agcttgattt atttagtgga ttcttgagga tgtatgctgg
    44341 tatcaatcga gaaaatcgta accaggctcg taaaatgatg aataatcaac tgcttgattt
    44401 aaaaaaaggt tattttacag agtttgagtt aaatcagacc aaggaaatga ttcgttggtc
    44461 gttgttactt tctcaagata atcaatcttc attgattgaa cgtgcttatc aaaatgcctt
    44521 atttggaaaa tcttcagcag actttaaagg ttggattgca aaactcgagc aagttgacaa
    44581 agatgatatt tgtagagcag ctaataatgt gaaactacag gcgatttact ttatggaagg
    44641 aatagaatga caaaggttgt ttttgaaaaa aaatactatc cagctgtaaa agaaatgatt
    44701 tatcgaactc gtttgtcaaa tggattgaca gttgctcttt tgcctaaaaa ggaatttaaa
    44761 gaggtttacg ggagtgtaac tgtacagttt ggttcgatag atacgcttgt cacagaaatt
    44821 gacggagatg taaaaaaata tcctgcagga attgctcatt ttcttgaaca taaattattt
    44881 gaaagagaag attctagtga tttgatgtcg gcttttacga gtctaggtgc agatagtaat
    44941 gcctttacaa gctttacaaa aacaaactat cttttttcag caacggatta ttttttagaa
    45001 aatttagatt tacttgatga attggtaaca tcagcacact ttactgaagc ttccattctg
    45061 acagagcagg atattattca gcaagaacga gaaatgtacc aagatgatcc agattcgtgt
    45121 ttattctttt caactttagc gaatttgtat cctggtacac ctttagcaac tgatatagtt
    45181 ggaagtgagg agtccatttc ccaaatcaat ctaactaatt tgcaagaaaa ttttacaaag
    45241 ttttacaaac ctgtaaacat gtctctgttt ttagttggta attttgatgt ggagcgagta
    45301 caggactatt ttgaaagcaa agaactgaaa gattcagatt ttcaggaagt agcaagagaa
    45361 aagttgtttt tacagcctgt aaagccaaca gatagtatga gaatggaagt atcttctccc
    45421 aaactagcga ttggagttag aggtaagcga gaagtttctg aagcggattg ctatcgacat
    45481 catattttat taaaattatt gtttgcaatg atgtttggtt ggacttcgga tcgttttcaa
    45541 aaatgttatg aatcaggtaa aattgatgta tccttatctc tggaagttga agtaacaagt
    45601 cgctttcatt ttgtcatgtt gacaatggat acgaaagagc cagttgcttt gtctcatcaa
    45661 tttaggaagg ctattcgtaa ttttacaaag gatttagata ttacagagga acatttagat
    45721 attatcaaaa gagagatgtt tggcgaattt ttcagtagca tgaactctct tgaatttatt
    45781 gcaacgcaat atgatgcttt tgaaaatggt gagacaattt ttgatttgcc gaaaatttta
    45841 caggaaatta ctttagagga tgtccttgat gctggacatc atttaataga tgatggtgac
    45901 atagttgatt ttacaatatt cccatcgtag taacctatta taatagacac tagaaagaag
    45961 ggatgacaag tatgagaaaa aaaacaattg gagaggtttt acgattagct agaatcaatc
    46021 agggattgag tttagatgaa ttgcagaaaa agacagaaat ccagttagat atgttggaag
    46081 caatggaagc agacgatttc gatcaacttc caagtccttt ttacacgcgt tctttcttga
    46141 aaaaatatgc atgggctgtt gagttagatg accaaattgt tttggatgct tatgattctg
    46201 ggagtatgat tacttatgag gaagtagatg ttgatgaaga tgagttgaca ggtcgtagac
    46261 gttcaagtaa gaaaaagaag aaaaaaacat catttttacc tttattttat tttatccttt
    46321 ttgctttatc gattttaatt tttgtgactt attatgtttg gaactatatt caaactcaac
    46381 cagaggagcc ttctctttct aattacagtg tggttcaatc aacaagttca actagctctg
    46441 ttccccactc ctcaagtagt agttcttcta gtatagaatc agctataagt gtatcaggcg
    46501 aaggaaatca tgtagaaatc gcttataaga caagtaagga aacagttaaa ttgcaattgg
    46561 cagtttcaga tgttacaagt tgggtcagtg tttcagaaag cgaacttgag ggcggtgtaa
    46621 ccttatcgcc aaagaagaaa agtgcagaag caacagttgc aactaaaagt cctgtaacaa
    46681 ttacgttagg tgttgtaaaa ggtgttgatt tgacagtaga taatcagact gttgatttat
    46741 cgaaattaac agctcagact ggacaaatca ctgtaacctt tactaaaaat taaggaaaaa
    46801 cgaatgaaaa aagaacaaat tcccaatctc ttaacaatag gtcgaattct ctttatacct
    46861 atttttatct ttattttaac gataggaaat tcgatagaga gtcatatagt tgcagctatt
    46921 atctttgctg ttgccagtat taccgactat ttagatggat atttagctcg taaatggaat
    46981 gtggtcagta attttggtaa atttgcagat cctatgtcgg ataagttact agttatgtcg
    47041 gcttttatta tgttgattga gttaggtatg gctccggctt ggattgttgc agtgattatc
    47101 tgtcgtgagt tagctgtgac aggtttaagg cttttattgg ttgaaactgg tggaacaatt
    47161 ttagcagcag caatgcctgg aaaaattaaa acttttagtc agatgtttgc cattattttc
    47221 ttgctattac attggacttt gcttggtcaa gttctacttt atgtagcctt atttttcact
    47281 atctactctg gctatgacta tttcaagggt agtgcctatg tatttaaagg gacatttggt
    47341 tcgaaatgaa atcaataatt gatgtaaaaa atctttcttt tcgctataaa gaaaatcaga
    47401 actactacga tgtgaaggat attacgtttc acgtgaaacg tggagaatgg ctttcgattg
    47461 tagggcataa tggtagtggt aaatcaacga cggttcgatt aattgatggc ttactggaag
    47521 cagaatccgg agagattgta attgatggcc aacgtttgtc tgaggaaaat gtttggaata
    47581 tacgtcgtca aatcggtatg gtttttcaaa atccagacaa tcaatttgtt ggagcgactg
    47641 ttgaagatga tgttgctttt ggtttggaaa atcagggact ttctcgtcaa gaaatgaaaa
    47701 agagagtgga agaagctctg gctttagttg gcatgttgga ctttaaaaag agagagccag
    47761 cgcgtctatc aggtggtcaa aagcaacgtg tggccattgc aggtgttgta gccctaagac
    47821 cagctatttt aatcttagat gaagcaacga gtatgttgga tcctgagggg cgtagagaac
    47881 ttattgggac agtaaaagga attcgaaaag actatgatat gacggtcatt tctattaccc
    47941 atgatttgga agaagtcgcc atgagtgatc gcgtattggt catgaaaaaa ggggaaattg
    48001 aatcaactag tagtccaagg gagcttttct ctcgaaatga tttagatcaa attggattag
    48061 acgatccttt tgctaatcaa ttaaaaaaat ctttgagcca gaatggctat gatttacctg
    48121 aaaattattt gacagaaagt gagctagagg ataagctatg ggaattgctc tagaaaatgt
    48181 gaattttaca tatcaagaag gtactccctt agcttcagca gctttgtcgg atgtttcttt
    48241 gacgattgaa gatggctctt atacagcttt aattgggcac acaggtagtg gtaaatcaac
    48301 tattttacaa ctcttaaatg gtttattggt gccaagtcaa gggagtgtga gggtttttga
    48361 taccttaatc acctcgactt ctaaaaataa agatattcgt caaattagaa aacaggttgg
    48421 cttggtattt cagtttgctg aaaatcagat ttttgaagaa acggttttga aggacgttgc
    48481 ttttggaccg caaaattttg gagtttctga agaagatgct gtgaagactg cgcgtgagaa
    48541 actggctctg gttggaattg atgaatcact ttttgatcgt agtccgtttg agctgtcagg
    48601 gggacaaatg agacgtgttg ccattgcagg catacttgcc atggagccag ctatattagt
    48661 cttagatgag ccaacagctg gtctagatcc tctagggaga aaagagttga tgaccctgtt
    48721 caaaaaactc caccagtcag ggatgaccat cgtcttggta acgcatttga tggatgatgt
    48781 tgctgaatat gcgaatcaag tctatgtaat ggaaaaggga cgtttagtaa aggggggcaa
    48841 accaagtgat gtctttcaag acgttgtttt tatggaagaa gttcagttgg gagtacctaa
    48901 aattacggcc ttttgtaaac gattggctga tagaggcgtg tcatttaaac gattaccgat
    48961 taagatagag gagttcaagg agtcgctaaa tggatagtat gattttgggg cgttatatcc
    49021 caggggattc gattgttcac cgattggatc cacgtagcaa attgcttgct atgatgctac
    49081 tgattttgat tgtgttttgg gctaataacc ccttgacgaa tctgattctt tttatagcga
    49141 cagggatatt tattgccttg tcaggagtat ctctttcatt ttttattcag ggcttgaagt
    49201 ctatgttttt cttgattgcc ttcacaacta tttttcaact atttttcatt tctaatggga
    49261 atgttttatt tgagttttcg tttgtgagaa tcacggatta tgctttgcaa caagctggga
    49321 ttattttttg tcgctttgta ttgattattt tcttttcaac tttgttaacc ttaacaacca
    49381 tgcctttaag tttggcatca gctgtcgaag ctttattagc acctttaaag cgtgtgaaag
    49441 ttccagttca tgaaattgga ttgatgctgt ctatgagttt gcgttttgtc ccaaccttga
    49501 tggatgatac gacgcggatt atgaatgcac agaaagctcg tggagtggat tttggagaag
    49561 gaagcatcgt tcaaaaagta aaggcgatga ttcccatttt gattcctctt tttgcgacaa
    49621 gtttaaaacg tgcagattcc ttggctatcg ctatggaagc gcgtggctat cagggtggaa
    49681 aaggcagaag tcaataccga caattgaaat ggactctaaa ggatacgttg accattcttg
    49741 ttattctcgt acttggttgt tgtttatttt tcttaaaatc ttagtagctt tcaggaattg
    49801 ataaaaagtt actgtaacag tttttgatat aaaggtagga atatgaaccg ttttaaaaaa
    49861 tcaaaatatg tcattattgt ttttgtcact gttctgcttg tgtcagctct cttagcgacg
    49921 acttattcaa gtacaattgt gacaaaatta ggagatggaa tctcattggt tgatagagtt
    49981 gtacaaaaac cttttcagtg gtttgattct gtcaaatcag atttggctca tttgacacga
    50041 acatataatg aaaatgaaag tttgaagaaa cagctttacc aattagaagt taaatcaaat
    50101 gaggtggaaa gtttaaagac agaaaatgaa caactgcgcc aattgcttga tatgaagtct
    50161 aaattgcaag ccacaaagac tttagcagca gatgttatta tgcgttctcc ggtatcttgg
    50221 aagcaggagt tgaccttaga tgcaggtaga tcaaaaggtg cttctgagaa catgttagct
    50281 attgcaaatg gtggcttgat tgggagtgtt tcaaaagtag aggagaactc tactatagtc
    50341 aaccttctga caaatacgga aaatgctgat aagatttctg ttaaaattca acatggctct
    50401 actacaattt atggaattat tattggctat gacaaggaaa atgacgttct taaaattagc
    50461 caattaaata gtaatagcga tattagtgcg ggagataagg tgactactgg tggattagga
    50521 aactttaacg ttgctgatat tcctgttggt gaagtggttg ccacaacgca tagtacagac
    50581 tatttgacac gagaagtaac tgttaaattg agtgcagata ctcataatgt agatgtgata
    50641 gaattagtgg ggaattcata atgagacagt tgaagcgagt tggagtattt ttattgcttc
    50701 ctttctttgt tctaattgac gcccatatta gccagcttct gggctcattt ttcccccatg
    50761 tacatttggc tagtcatttt ctttttctat ttctcttatt tgagacgata gaagtatcag
    50821 agtatctcta cctagtctat tgttttgtta taggcttggt ttatgatgtt tactttttcc
    50881 atctaatagg gattacaact ctcttattta tcttattggg agccttcctt cataaattga
    50941 atagtgttat tttgttgaat cgttggacaa gaatgctagc tatgattgtg ctgacattcc
    51001 tgtttgaaat gggtagttat cttttggctt ttatggtagg gttgacagta gatagcatgt
    51061 cgatttttat agtctatagc ttggtaccga cgatgatttt aaatttttta tggattactg
    51121 tttttcaatt tatttttgaa aaatattatc tataagaacg acatataaat gtaacaaagg
    51181 cgtaatattt attaggcctt tttttggtat actagtattg tctttaaaag aaggagtatc
    51241 tacgtaatat gaagaaaaaa atcttagcgt cacttttatt aagtacagta atggtttctc
    51301 aagtagctgt tttaacaact gcgcatgcag aaacgactga tgacaaaatt gctgctcaag
    51361 ataataaaat tagtaactta acagcacaac aacaagaagc ccaaaaacaa gttgaccaaa
    51421 ttcaggagca agtatcagct attcaagctg agcagtctaa cttgcaagct gaaaatgata
    51481 gattacaagc agaatctaag aaactcgagg gtgagattac agaactttct aaaaacattg
    51541 tttctcgtaa ccaatcgttg gaaaaacaag ctcgtagtgc tcaaacaaat ggagccgtaa
    51601 ctagctatat caataccatt gtaaactcaa aatcaattac agaagctatt tcacgtgttg
    51661 ctgcaatgag tgaaatcgta tctgcaaaca acaaaatgtt agaacaacaa aaggcagata
    51721 aaaaagctat ttctgaaaaa caagtagcaa ataatgatgc tatcaatact gtaattgcta
    51781 atcaacaaaa attggctgat gatgctcaag cattgactac gaaacaggca gaactaaaag
    51841 ctgctgaatt aagtcttgct gctgagaaag cgacagctga aggggaaaaa gcaagtctat
    51901 tagagcaaaa agcagcagct gaggcagagg ctcgtgcagc tgcggtagca gaagcagctt
    51961 ataaagaaaa acgagctagc caacaacaat cagtacttgc ttcagcaaac actaacttaa
    52021 cagctcaagt gcaagcagta tctgaatctg cagcagcacc tgtccgtgca aaagttcgtc
    52081 caacatacag tacaaacgct tcaagttatc caattggaga atgtacatgg ggagtaaaaa
    52141 cattggcacc ttgggctgga gactactggg gtaatggagc acagtgggct acaagtgcag
    52201 cagcagcagg tttccgtaca ggttcaacac ctcaagttgg agcaattgca tgttggaatg
    52261 atggtggata tggtcacgta gcggttgtta cagctgttga atcaacaaca cgtatccaag
    52321 tatcagaatc aaattatgca ggtaatcgta caattggaaa tcaccgtgga tggttcaatc
    52381 caacaacaac ttctgaaggt tttgttacat atatttatgc agattaattt acagagggac
    52441 tcgaatagag ccctcttttc aggttttacc gtgacaatcc ctattaaaaa ttatatcaaa
    52501 atagcttgaa aatattggaa aagtatggta aaatgaaaat tgtcgtgtga acgataatac
    52561 tcattcttga tgaattgtga agcagttgcc cttgggtcgt tttgcgagtt gaagtcaaga
    52621 agaggaaaaa aacaaaaagg agaaatactc atggcagtaa tttcaatgaa acaacttctt
    52681 gaggctggtg tacactttgg tcaccaaact cgtcgctgga atcctaagat ggctaagtac
    52741 atctttactg aacgtaacgg aatccacgtt atcgacttgc aacaaactgt aaaatacgct
    52801 gaccaagcat acgacttcat gcgtgatgca gcagctaacg atgcagttgt attgttcgtt
    52861 ggtactaaga aacaagcagc tgatgcagtt gctgaagaag cagtacgttc aggtcaatac
    52921 ttcatcaacc accgttggtt gggtggaact cttacaaact ggggaacaat ccaaaaacgt
    52981 atcgctcgtt tgaaagaaat taaacgtatg gaagaagatg gaactttcga agttcttcct
    53041 aagaaagaag ttgcacttct taacaaacaa cgtgcgcgtc ttgaaaaatt cttgggtggt
    53101 atcgaagata tgcctcgtat cccagatgtg atgtacgtag ttgacccaca taaagagcaa
    53161 atcgctgtta aagaagctaa aaaattggga atcccagttg tagcgatggt tgacaccaat
    53221 actgatccag atgatatcga tgtaatcatc ccagctaacg atgacgctat ccgtgctgtt
    53281 aaattgatca cagctaaatt ggctgacgct attatcgaag gacgtcaagg tgaggatgca
    53341 gtagcagttg aagcagaatt tgcagcttca gaaactcaag cagattcaat tgaagaaatc
    53401 gttgaagttg tagaaggtga caacgcttaa tttatacaaa tagtaattac ctaggagggc
    53461 ggggcttagc ccggctctcc tattttcaaa aaatatagga gaattaaaat ggcagaaatt
    53521 acagctaaac ttgtaaaaga gttgcgtgaa aaatctggtg ccggtgttat ggacgctaaa
    53581 aaagcgcttg tagaaacaga cggtgacatc gaaaaagcga ttgaattgct tcgtgaaaaa
    53641 ggtatggcta aggcagctaa gaaagctgac cgtgttgctg cagaaggttt gactggtgtt
    53701 tatgttaacg gtaatgttgc agcagttatt gaagtaaacg ctgaaactga cttcgttgca
    53761 aaaaacgctc aattcgttga attggtaaat actacagcta aagtcattgc tgaaggaaaa
    53821 cctgctaata atgaagaagc tcttgctttg ataatgcctt caggtgaaac tcttgaagct
    53881 gcatacgtat ctgcaacagc aactatcgga gagaaaatct cattccgtcg ctttgcattg
    53941 attgaaaaaa cagacgcaca acactttgga gcataccaac ataacggtgg acgtatcggt
    54001 gttatttcag ttgttgaagg tggagacgaa gcacttgcta aacaattgtc aatgcacatc
    54061 gcagcgatga aaccaacagt tctttcttac aaagaattgg atgagcaatt cgttaaagat
    54121 gagttggcac aattgaatca cgttatcgac caagacaacg aaagccgtgc aatggttaat
    54181 aaaccagctc ttccacactt gaagtatgga tcaaaagctc aattaactga tgatgttatt
    54241 gctcaagctg aagctgacat caaagctgaa ttggctgcag aaggcaaacc agaaaaaatc
    54301 tgggacaaaa ttatcccagg taaaatggat cgcttcatgc ttgataatac taaagttgac
    54361 caagcttaca cacttcttgc acaagtttac atcatggatg acagcaagac agttgaagca
    54421 taccttgaat cagttaacgc ttcggtagtt gagtttgctc gctttgaagt tggtgaaggt
    54481 atcgagaaag ctgcaaacga cttcgaagct gaagttgcag ctacaatggc agcagccttg
    54541 aataactaat aatagaaagg aagcaatttg cttccttttt tgtatagggc ttatattttt
    54601 cctgaaattg tttttccccc agtctcactc gattagaata attaaaacaa aaagccctat
    54661 aataagggct aagtgcattt aggagactat acttcaaatt catagtaagc gcgtcataac
    54721 aaggtatcta tcctaattcc ccaacttcca gtatactaga taaaaaataa ttatcggagg
    54781 aaaggtattg tactatgatg attcaactaa gtgatttagg tcaagttcac attgtttgtg
    54841 gcaagacaga tatgaggcag ggaatagact cattagccta tgtagttaaa acccactttg
    54901 aattggattc tttctccggt caagtctttc tcttttgtgg tggacgtaaa gaccgcttta
    54961 aagtccttta ctgggatggt caaggatttt ggctactata taaacgcttt gagaacggaa
    55021 aactgacttg gctaagtaca gaaaaggatg tcaaagctct cacatctgaa caagtagact
    55081 ggcttatgaa gggcttttct atcactcccc aaatatagtg gtttgaaact agaatagtac
    55141 acctctgctt ctaaaacatt gttagaaatc gatttgactg tcctgttctt atttcatttt
    55201 actataaatt catcagaaag tcgtgatttc tattgaaatg aggactttct ttttatactc
    55261 atctgttttc acaaagcatt ctagtccatc tccgattaac gatggacttt atcacctcct
    55321 tctccagtcc ttgtataaca tcttggagtt gattcatgac atcttccaaa atttgaaagg
    55381 ctttattctt aaatccacgt ttacgaatct ctttccacac ttgttcaatg gggttcatct
    55441 ctggtgtgta tggaggaata aatgcaaagc caatattagt cggaatcttt aaggtacttg
    55501 atttatgcca tatagcattg tccataacga gtaaaagata atcatctgga taagcttgtg
    55561 aaatctccta ttcctaaagc ccctttagcg cataactttg gctcagcttc tattatcgct
    55621 cacaccatcc atcagaagtt taatctgaag gtacccaatt atcgccaaga agaagattgg
    55681 gctaggatgg gtttaccaat cacacgtaag gaaatctcta atcggcatat caagacgagt
    55741 caatactatt tggagcccct ttataacctc ttgcgagaga gactattgac tcagccctta
    55801 cttcatgcgg atgaaacttc ttatagggtg ctagagagtg atagtcagct gacttactat
    55861 tggacttttt tgtctgggaa agctgagaaa caagggatta cgctttacca tcatgtccta
    55921 atcgatttgt tcatatctta tttcaatcca ttataaatag tgagaaatat ctatcctatc
    55981 ttctagaatg tcttccaaac gtggaaactc tcgtaaacaa agaggtttta gaggcctatt
    56041 taccatggac taaagttgta caagaaaagt gcaaataaga aatctccaga ttaggaacta
    56101 tccgtgagtt ctctagtctg gagatttttc aatagacttc gttattggac ggttacaatt
    56161 cataaagtgc tgtagagaga taacgttcac cgttatctgg tgctagggca aggacttttt
    56221 tacctgtacc taattttttg gcaacctcga tggctccgta gatagctgca gctgaggaaa
    56281 tccctacaag gaagccttct tttccaccaa tttcacgtcc gagtgcaaga gcgtcatctg
    56341 atgttacacg aacgatacca tcataggctt tagtatcaag tgtatcagga ataaatccag
    56401 ctgagatacc ttgaattttg tgaggaccag gtttttcacc agatagaata gcagattcat
    56461 ctgcttctac tgcaaaaact tgaatgttag aattttctga tttgagtgca tgagaaacac
    56521 cagaaatcgt tccaccagta cctactccag caacaaaggc atctaatcca tctttaccga
    56581 aagcagctag tatctcagct cctgttgttc tttcgtgtac ttctggatta gctggattgt
    56641 caaattgaag aggaaggaaa ccatcacgtt cagcagcgat ttcttgagcc ttagcaatag
    56701 cacctttcat tccctcgcta ccaggagtta ggacgagttc agcaccataa gcttggataa
    56761 ttttacgtcg ttctacactc atagtttcag gcataacgat gacgacttta taccctttag
    56821 cagcacctac ccatgaaagt ccaataccgg tgtttccact tgttgcttca acaatagtag
    56881 aaccaagttt cagaatacca tcttgttcag ctttttcaat catgctaagg gcaatacggt
    56941 cttttacaga tgaaccagga ttaaatgctt caagctttat atagacgtct gcagcacctt
    57001 ctggcacgat gttgttaagt ttaacaatcg gtgtttgacc gattaattca gtaatgttgt
    57061 tataaataga catatgaata cctctttgta taagatatct ttagtataac gctatccata
    57121 ccatttgtaa aatatagaaa tcctatcgaa gcgataggat ttctatatat catagatcaa
    57181 agtcattaat tttcaagtga ttgcgttcag ttaattctag taaataggtg tgaaggaaaa
    57241 cgatatcagg tttcgtttga attgcttcat tttctagtat attttggtac gcatcttttt
    57301 attttgctcg ctaaagtagt tgtgagaatg tcaacgaaac gctgtattat tcattgttta
    57361 cactaagttt acaggaactt caacctctcg taaaccttgg tcagttaaag tgacttttcc
    57421 attaaaaaac tccacaagtg cagctttaat agtttctttt tcttctttat caacataaat
    57481 catcgtatcg acttgatctg taaagtttgt atccagctcc atgagatcat gttctttaag
    57541 gaagttactg tactcttggt actgagcata agacatttga atagcaatgc cagcctgttc
    57601 ttttatttca ataataccaa tttctttgac agctaaggcg acactgccgg cgtaagcacg
    57661 aattagtcct ccagcgccta gtttaatacc accaaagtag cgtgtcacga ccacacagac
    57721 attggtgaga ttgtgatttt ctagtacccc aagcatggga acaccagcag taccactagg
    57781 ctcaccatca tcacttgtac gtttaatttc actacgttct ccaataatga aggcagagca
    57841 gttatgtgtc gctttgtagt gttctttttt gatggcagta atgaagtcac gagcctcttc
    57901 ttcgctataa acacgcttgg catggcagat aaagcgagat tttttgattt cttcttggac
    57961 ttgaccgtcc tctttaattg tcctaaattc catgatttaa ttgtactaaa aaatcatcta
    58021 aagtgctagt ttttacgaat aaagaagtat gaaagtaaat ttagattatc tcggtcgttt
    58081 atttactgag aatgaattaa cagaagaaga acgtcagttg gcggagaaac ttccagcaat
    58141 gagaaaggag aaggggaaac ttttctgtca acgctgtaat agtactattc tagaagaatg
    58201 gtatttgccc atcggtgctt actattgtcg agagtgcttg ctgatgaagc gagtcagaag
    58261 tgatcaaact ttatactatt ttccgcagga ggattttcca aagcaagatg ttctcaaatg
    58321 gcgcggccaa ttaactcctt ttcaagagaa ggtgtcagag ggattgcttc aagtagtaga
    58381 caagcaaaag ccaaccttag ttcatgcggt aacaggagct ggaaagacag aaatgattta
    58441 tcaagtagtg gctaaagtga tcaatgcggg tggtgcagtg tgtttggcta gtcctcgcat
    58501 agatgtttgt ttggagctgt acaagcgcct gcaacaggat ttttcttgcg ggatagcttt
    58561 gctacatgga gaatcggaac cttattttcg aacaccacta gttgttgcaa caacccatca
    58621 gttattgaag ttttatcaag cttttgattt gctgatagtg gatgaagtag atgcttttcc
    58681 ttatgttgat aatcccatgc tttaccacgc tgtcaagaat agtgtaaagg agaatggatt
    58741 gagaatcttt ttaacagcga cttcgaccaa tgagttagat aaaaaggtcc gtttaggaga
    58801 actaaaaaga ctgaatttac cgagacggtt tcatggaaat ccgttgatta ttccaaaacc
    58861 aatttggtta tcggatttta atcgctactt agacaagaat cgtttgtcac caaagttaaa
    58921 gtcctatatt gagaagcaga gaaagacagc ttatccgtta ctcatttttg cttcagaaat
    58981 taagaaaggg gagcagttag cagaaatctt acaggagcaa tttccaaatg agaaaattgg
    59041 ctttgtatct tctgtaacag aggatcgatt agagcaagta caagcttttc gagatggaga
    59101 actgacaata cttatcagta cgacaatctt ggagcgcgga gttaccttcc cttgtgtgga
    59161 tgttttcgta gtagaggcca atcatcgttt gtttaccaag tctagtttga ttcagattgg
    59221 tggacgagtt ggacgaagca tggatagacc gacaggagat ttgcttttct tccatgatgg
    59281 gttaaatgct tcaatcaaga aggcgattaa ggaaattcag atgatgaata aggaggctgg
    59341 tctatgaagt gcttgttatg tgggcagact atgaagactg ttttaacttt tagtagtctc
    59401 ttacttctga ggaatgatga ctcttgtctt tgttcagact gtgattctac ttttgaaaga
    59461 attggggaag agaactgtcc aaattgtatg aaaacagagt tgtcaacaaa gtgtcaagat
    59521 tgtcaacttt ggtgtaaaga gggagttgaa gtcagtcata gagcgatttt tacttacaat
    59581 caagctatga aggatttttt cagtcggtat aagtttgatg gagacttcct gttaagaaaa
    59641 gttttcgctt catttttaag tgaggagttg aaaaagtaca aagagtatca atttgttgta
    59701 attcccctaa gtcctgatag atatgctaat agaggattta atcaggttga gggcttggta
    59761 gaggcagcag gctttgagta tctggattta ttagagaaaa gagaagagag agccagttct
    59821 tctaaaaatc gttcagagcg cttggggaca gaacttcctt tctttattaa aagtggagtc
    59881 actattccta aaaaaatcct acttatagat gatatctata ctacaggagc aactataaat
    59941 cgtgttaaga aactgttgga agaagctggt gctaaggatg taaaaacatt ttcccttgta
    60001 agatgaggaa aaaatttgca aaaatagaat gaaagcgtta taataaaatc ataaaaacaa
    60061 aaatgtttag aaagaaggta ctcatatgat taaatatagt atccgtggtg aaaacctaga
    60121 agtaacagaa gcaattcgtg attatgtagt ttctaaactc gaaaagatcg aaaagtactt
    60181 ccaaccagaa caagagttgg atgcccgaat taacttaaaa gtttatcgtg aaaaaacggc
    60241 taaagtggaa gtaacgattc cgcttggatc tattactctc cgcgcagaag atgtatctca
    60301 agatatgtat ggttcaattg accttgtaac tgataaaatt gaacgtcaga ttcgtaaaaa
    60361 taaaacaaaa atcgagcgta aaaataaaaa taaggtagca actggtcaat tatttacaga
    60421 tgctttggtg gaagattcaa atattgtcca gtctaaagtt gttcgttcaa aacaaattga
    60481 tttaaaacca atggatttgg aagaagcaat tctacaaatg gatttattgg ggcatgattt
    60541 ctttatctat gtggatgttg aagatcagac aaccaatgtg atttatcgtc gtgaggatgg
    60601 cgaaattggt ttgttagagg ttaaagaatc ttaatttcaa tatgtgtaaa ggtaggttta
    60661 ctgaattgta aactaccttt ttcttataat tgatagaatt actgattaca cttttaaaaa
    60721 gtcgcttttt gaggggtatt atggtataat gggtgccaag aggttttgaa tgaaaaaatt
    60781 ttatgtaagt ccaatttttc ctattctagt aggattgatt gcgtttggag tcttatccac
    60841 tttcattatt tttgttaata ataatctgtt gacggtttta attttgtttc tttttgtagg
    60901 aggctatgtt tttttattta agaaactgag agtgcattat acaaggagtg atgtagaaca
    60961 gatacagtat gtaaaccacc aagcggaaga aagtttgaca gctctattgg aacagatgcc
    61021 tgtaggtgtt atgaaattga atttatcttc tggagaggtt gagtggttta atccctatgc
    61081 tgaattgatt ttgaccaagg aagatggtga ttttgattta gaagctgttc aaacgattat
    61141 caaggcttca gtaggaaatc cgtctactta tgccaagctt ggtgagaagc gttatgctgt
    61201 tcatatggat gcttcttccg gtgttttgta ttttgtagat gtatccaggg aacaagccat
    61261 aacagatgaa ttggtaacaa gtagaccagt gattgggatt gtctctgtgg ataattatga
    61321 tgatttggag gatgaaactt ctgagtcaga tattagtcaa atcaatagtt ttgtagctaa
    61381 ttttatatca gagttttcag aaaaacacat gatgttttct cgtcgggtaa gtatggatcg
    61441 attttatcta tttactgact acacggtgct tgagggcttg atgaatgata aattttctgt
    61501 tattgatgct ttcagagaag agtcgaaaca gagacagttg cccttgacct taagtatggg
    61561 attttcttat ggcgatggaa atcatgatga gatagggaaa gttgctttgc tcaatttgaa
    61621 cttggctgaa gtacgtggtg gcgaccaggt ggttgttaag gaaaacgacg aaacgaaaaa
    61681 tccagtttat tttggtggtg ggtctgctgc ttcaatcaag cgtacacgga ctcgtacgcg
    61741 cgctatgatg acagctattt cagataagat tcggagtgta gatcaggttt ttgtagtcgg
    61801 tcacaaaaat ttagacatgg atgctttggg ctctgctgta ggtatgcagt tgttcgccag
    61861 caatgtgatt gaaaatagct atgctcttta tgatgaagaa caaatgtctc cagatattga
    61921 acgagctgtt tcattcatag aaaaagaagg agttacgaag ttgttgtctg ttaaggatgc
    61981 aatggggatg gtgaccaatc gttctttgtt gattcttgta gaccattcaa agacagcctt
    62041 aacattatca aaagaatttt atgatttatt tacccaaacc attgttattg accaccatag
    62101 aagggatcag gattttccag ataatgcggt tattacttat atcgaaagtg gtgcaagtag
    62161 tgccagtgag ttggtaacgg aattgattca gttccagaat tctaagaaaa atcgtttgag
    62221 tcgtatgcaa gcaagtgtct tgatggctgg tatgatgttg gatactaaaa atttcacctc
    62281 gcgagtaact agtcggacat ttgatgttgc tagctatctc agaacgcgcg gaagtgatag
    62341 tattgctatc caggaaatcg ctgcgacaga ttttgaagaa tatcgtgagg tcaatgaact
    62401 tattttacag gggcgtaaat taggttcaga tgtactaata gcagaggcta aggacatgaa
    62461 atgctatgat acagttgtta ttagtaaggc agcagatgcc atgttagcca tgtcaggtat
    62521 tgaagcgagt tttgttcttg cgaagaatac acaaggattt atctctatct cagctcgaag
    62581 tcgtagtaaa ctgaatgtac aacggattat ggaagagtta ggcggtggag gccactttaa
    62641 tttggcagca gctcaaatta aagatgtaac cttgtcagaa gcaggtgaaa aactgacaga
    62701 aattgtatta aatgaaatga aggaaaagga gaaagaagaa tgaaagtaat ctttttagca
    62761 gatgttaaag gaaaaggtaa aaaaggcgaa attaaggaag taccaacagg gtatgcgcaa
    62821 aactttctta tcaaaaagaa tctagccaaa gaagcgactg ctcaagctgt aggtgaactt
    62881 cgtggtaaac aaaaatcgga agaaaaagct cacgctgaga tgattgcaga aggaaaagca
    62941 attaaagcac aacttgaagc agaagaaact gttgtagaat ttgttgaaaa agttggtcca
    63001 gatggtcgta cctttggttc tattaccaat aagaagattg cagaagaatt gcaaaagcaa
    63061 tttggaatta agattgataa acgtcatatt caagtacaag ctccgattcg agcggttggt
    63121 ttgattgatg tgccagtgaa aatctatcaa gatatcacaa gtgtaatcaa tcttcgtgtg
    63181 aaagaaggat aagtttacac cttcttgaca agattgtaaa aggaagggaa gtctgatggc
    63241 agaagtagaa gagttacgag tacaacctca agatatctta gctgagcaat ccgttttagg
    63301 ggctatcttt attgatgaga gtaaacttgt ttttgtgcga gaatacattg agtctcggga
    63361 cttttttaag tatgcccatc gtttgatttt ccaagccatg gtcgatttat ccgatcgtgg
    63421 tgatgccata gatgcaacaa cggttcgtac tatccttgat aatcaaggtg atttacagaa
    63481 tattggtggc ttgtcttact tggttgagat tgttaattct gtgccaactt ctgctaatgc
    63541 ggagtattat gctaagattg ttgcagaaaa agcaatgcta cgtcgtttaa ttgccaagtt
    63601 gacagagtct gtcaaccaag cttacgaagc gtcacaacca gctgatgaaa ttattgctca
    63661 ggcagaaaaa gggttgattg atgtcagtga aaatgcaaat cgaagcgggt ttaagaacat
    63721 tcgagatgtg ttgaatctca actttggaaa tctggaagct cgctcgcaac aaacgaccga
    63781 tattacaggt attgcgacag gttatcgtga tttggatcat atgacaacag gacttcatga
    63841 ggaggagttg attatcttag cagctcgtcc agcagttggt aagacagcat ttgccttgaa
    63901 tatcgctcag aacattggga ctaagttgga caaaacggtt gctatttttt cactcgaaat
    63961 gggtgcggaa agcttggtag atcgtatgtt agctgcagaa ggcttagtgg agtcacattc
    64021 tatccgtaca gggcaattga cagatgagga gtggcaaaaa tatactattg ctcagggtaa
    64081 tctagctaac gccagtatct atatcgatga tacgccaggt attcggatta cagagattcg
    64141 ttctcgttct cgtaaattgg ctcaagaaac tggaaatctt ggtttgattt tgatagacta
    64201 tttgcaactt atcacgggaa ctggtcgaga aaatcgtcaa caagaagttt ctgaaatttc
    64261 tcgtcagttg aaaatactag ccaaggaatt gaaggttcca gtaatcgctc tgagtcagct
    64321 ttctcgtggt gtagaacaac gtcaggacaa gagaccggtc ttgtctgata ttcgtgaatc
    64381 tgggtctatt gagcaggacg ctgatatcgt agcttttctc tatcgcgatg actactatga
    64441 acgtggtggt gaagaagagg agggtatccc aaataataag gtggaagtta ttatcgagaa
    64501 aaaccgtagt ggagctcgtg gaacagtgga attgattttc caaaaagaat acaataaatt
    64561 ttcaagtatc tcaaagaggg aggcataaga tgtcagatgc atttacagat gtagccaaga
    64621 tgaaaaaaat caaagaagaa atcaaggcac atgagggaca agtcgtagaa atgactttgg
    64681 agaatggtcg taagcgccaa aaaaatagat tgggtaagct aattgaagtt tatccatctc
    64741 tatttattgt ggagtttggg gatgtggaag gagataaaca agttaatgtt tacgttgaat
    64801 cctttactta ctcagatatt cttacagaaa agaatttgat tcattatctt gactaaagtg
    64861 agaaattttc tcactttttc ttttttctcc gaataattta ggtgaaggca atcatcgctt
    64921 tatattattt ttcaaggagg aagaatgaaa attttaccgt ttatagcaag aggaacaagt
    64981 tattacttga agatgtcagt taaaaagctt gttccttttt tagtagtagg attgatgcta
    65041 gcagctggtg atagtgtcta tgcctattcc agaggaaatg gatcgattgc gcgtggggat
    65101 gattatcctg cttattataa aaatgggagc caggagattg atcagtggcg catgtattct
    65161 cgtcagtgta cttcttttgt agcctttcgt ttgagtaatg tcaatggttt tgaaattccg
    65221 gcagcttatg gaaatgcgaa tgaatgggga catcgtgctc gtcgggaagg ttatcgtgta
    65281 gataatacac cgacgattgg ttccattact tggtctactg caggaactta tggtcatgtt
    65341 gcctgggtgt caaatgtaat gggagatcag attgagattg aggaatataa ctatggttat
    65401 acagaatcct ataataaacg agttataaaa gcaaacacga tgacaggatt tattcatttt
    65461 aaagatttgg atggtggcag tgttgggaat agtcaatcct caacttcaac aggcggaact
    65521 cattatttta agaccaagtc tgctattaaa actgaacctc tagctagcgg aactgtgatt
    65581 gattactatt atcctgggga gaaggttcat tatgatcaga tacttgaaaa agacggctat
    65641 aagtggttga gttatactgc ctataatgga agctatcgtt atgttcaatt ggaggctgtg
    65701 aataaaaatc ctctaggtaa ttctgttctt tcttcaacag gtggaactca ttattttaag
    65761 accaagtctg ctatcaaaac tgaaccccta gttagtgcaa ctgtgattga ttactattat
    65821 cctggagaga aggttcatta tgatcaaatt ctcgaaaaag acggctacaa gtggttgagt
    65881 tatacggctt ataacggaag tcgtcgctat atacagctag agggagtgac ttcttcacaa
    65941 aattatcaga atcaatcagg aaacatctct agctatggat cccatagtag ttcaactgtc
    66001 ggttggaaga aaataaatgg tagttggtat catttcaaat caaatggttc taaatcaaca
    66061 ggatggctga aagacggttc tagctggtat tatttgaaat tatctggtga aatgcagaca
    66121 ggatggttaa aggaaaatgg tttgtggtat tatctgggta gttcaggggc aatgaaaaca
    66181 ggctggtacc aggtctctgg taagtggtat tattcttact cttcaggcgc cttagctgtt
    66241 aatacgacgg tggatggcta cagagtaaac agtgatggag aacgagtata gaaaattgga
    66301 gtaggagaaa tttcctgctc ttttctgtaa gcagtttcct tgacattttt cttattttgc
    66361 gctatcatat atacatataa tatatgggag tctgtgtaca gtctgagagg aagtgttaaa
    66421 cttcgaccgc acctgatctg ggtaatgcca gcggagggaa cgatacttag tctaattttg
    66481 caccttttcc atgtatggta aaggtttttc tttttttaaa aaggaaaacg agaagaggag
    66541 gttcttatga aagcaagcat tgccttgcaa gttttacccc tagtacaggg gattgatcgg
    66601 atagctgtta ttgatcaggt cattgcttat ctgcaaactc aagaagtgac gatggtagtg
    66661 acaccatttg aaacggtctt ggaaggggag tttgatgagc ttatgcgcat tctaaaagaa
    66721 gcgctggaag tggcagggca ggaggcagac aatgtctttg ccaatgtcaa aataaatgta
    66781 ggagagattt taagtattga tgagaaactt gagaagtata ctgagacgac acattagtct
    66841 attgggcttt ctcggagtat tgtcaatctg gcagttagca ggttttctta aacttctccc
    66901 caagtttatc ctgccgacac ctcttgaaat tctccagccc tttgttcgtg acagagaatt
    66961 tctctggcac catagctggg cgaccttgag agtggcttta ctggggctga ttttgggagt
    67021 tttgattgcc tgtcttatgg ctgtgctcat ggatagtttg acttggctca atgacctgat
    67081 ttaccctatg atggtggtca ttcagaccat tccgaccatt gccatagctc ctatcctggt
    67141 cttgtggcta ggttatggga ttttgcccaa gattgtcttg attatcttaa cgacaacctt
    67201 tcccatcatc gttagtattt tggacggttt taggcattgc gacaaggata tgctgacctt
    67261 gtttagtctg atgcgggcca agccttggca aatcctgtgg cattttaaaa tcccagttag
    67321 cctgccttac ttttatgcag gtctgagggt cagtgtctcc tacgccttta tcacaactgt
    67381 ggtatctgag tggttgggag gttttgaagg tcttggtgtt tatatgattc agtctaaaaa
    67441 actgtttcag tatgatacca tgtttgccat tattattctg gtgtcgatta tcagtctttt
    67501 gggtatgaag ctggtcgata tcagtgaaaa atatgtgatt aaatggaaac gttcgtagaa
    67561 ttagaatgtt tctgaaaaag aaaagaggaa atcaaaatga agaaaacatg gaaagtgttt
    67621 ttaacgcttg taacagctct tgtagctgtt gtgcttgtgg cctgtggtca aggaactgct
    67681 tctaaagaca acaaagaggc agaacttaag aaggttgact ttatcctaga ctggacacca
    67741 aataccaacc acacagggct ttatgttgcc aaggaaaaag gttatttcaa agaagctgga
    67801 gtggatgttg atttgaaatt gccaccagaa gaaagttctt ctgacttggt tatcaacgga
    67861 aaggcaccat ttgcagtgta tttccaagac tacatggcta agaaattgga aaaaggagca
    67921 ggaatcactg ccgttgcagc tattgttgaa cacaatacat caggaatcat ctctcgtaaa
    67981 tctgataatg taagcagtcc aaaagacttg gttggtaaga aatatgggac atggaatgac
    68041 ccaactgaac ttgctatgtt gaaaaccttg gtagaatctc aaggtggaga ctttgagaag
    68101 gttgaaaaag taccaaataa cgactcaaac tcaatcacac cgattgccaa tggcgtcttt
    68161 gatactgctt ggatttacta cggttgggat ggtatccttg ctaaatctca aggtgtagat
    68221 gctaacttca tgtacttgaa agactatgtc aaggagtttg actactattc accagttatc
    68281 atcgcaaaca acgactatct gaaagataac aaagaagaag ctcgcaaagt catccaagcc
    68341 atcaaaaaag gctaccaata tgccatggaa catccagaag aagctgcaga tattctcatc
    68401 aagaatgcac ctgaactcaa ggaaaaacgt gactttgtca tcgaatctca aaaatacttg
    68461 tcaaaagaat acgcaagcga caaggaaaaa tggggtcaat ttgacgcagc tcgctggaat
    68521 gctttctaca aatgggataa agaaaatggt atccttaaag aagacttgac agacaaaggc
    68581 ttcaccaacg aatttgtgaa ataatgacag aaattagact agagcacgtc agttatgcct
    68641 atggtcagga gaggatttta gaggatatca acctacaggt gacttcaggc gaagtggttt
    68701 ccatcctagg cccaagtggt gttggaaaga ccaccctctt taatctaatc gctgggattt
    68761 tagaagttca gtcagggaga attgtccttg atggtgaaga aaatcccaag gggcgcgtga
    68821 gttatatgtt gcaaaaggat ctgctcttgg agcacaagac ggtgcttgga aatatcattc
    68881 tgcccctctt gattcaaaag gtggataagg cagaagctat ttcccgagcg gataaaattc
    68941 ttgcgacctt ccagctgaca gctgtaagag acaagtatcc tcatgaactt agcggtggga
    69001 tgcgccagcg tgtagcctta ctccggacct acctttttgg gcacaagctc tttctcttag
    69061 atgaggcctt tagcgccttg gatgagatga caaagatgga actccacgct tggtatcttg
    69121 agattcacaa gcagttgcag ctaacaaccc tgatcatcac gcatagtatt gaggaggccc
    69181 tcaatctcag cgaccgtatc tatatcttga aaaatcgccc tgggcagatt gtttcagaaa
    69241 ttaaactaga ttggtctgaa gatgaggaca aggaagtcca aaagattgcc tacaaacgtc
    69301 aaattttggc ggaattaggc ttagataagt agaaaaatag ggagttggtg aagattatcc
    69361 tttaccagcg ccctttttct tttaaaaatg agaaaatttc ggtataatag tcaaacaagg
    69421 tcaaggttta aagagagagg tgggtttgtt atgagattta aaaatacatc ggatcatatt
    69481 gaggcctaca tcaaggcgat tttagatcaa tctggtatcg tggagttgca acggagtcag
    69541 ttggcagata cctttcaggt tgttcctagt cagattaact acgtgatcaa gacacgcttt
    69601 acggaaagta gaggctactt ggttgaaagt aagcgtggtg gcggaggcta cattcgtata
    69661 ggacggattg agttttctag tcatcatgaa atgctccggg agctgcttta ctcgattggt
    69721 gagcgagtca gtcaagaaat ttatgaggat attctccagc ttttggttga gcaggaattg
    69781 atgaccaagc aggagatgaa tttgctagaa tcagtagctt tggatcgcgt tttaggagaa
    69841 gaagctccag ttgttcgagc aaacatgcta cgtcagatca tacaagaggt agatagaaaa
    69901 gggaagtaag atgaactatt caaaagcatt gaatgaatgt atcgaaagtg cctacatggt
    69961 tgctggacat tttggagctc gttatctaga gtcgtggcac ttgttgattg ccatgtctaa
    70021 tcacagttat agtgtagcag gggcaacttt aaatgattat ccgtatgaga tggaccgttt
    70081 agaagaggtg gctttggaac tgactgaaac ggactatagc caggatgaaa cctttacgga
    70141 attgccgttc tcccgtcgtt tgcaggttct ttttgatgaa gcagagtatg tagcgtcagt
    70201 ggtccatgct aaggtactag ggacagagca cgtcctctat gcgattttgc atgatagcaa
    70261 tgccttggcg actcgtatct tggagagggc tggtttttct tatgaagaca agaaagatca
    70321 ggtcaagatt gctgctcttc gtcgaaattt agaagaacgg gcaggctgga ctcgtgaaga
    70381 tctcaaggct ttacgccaac gccatcgtac agtagctgac aagcaaaatt ctatggccaa
    70441 tatgatgggc atgccgcaga ctcctagtgg tggtctcgag gattatacgc atgatttgac
    70501 agagcaagcg cgttctggca agttagaacc agtcatcggt cgggacaagg aaatctcacg
    70561 tatgattcaa atcttgagcc ggaagactaa gaacaaccct gtcttggttg gggatgctgg
    70621 tgtcgggaaa acagctctgg cccttggtct tgctcagcgt attgctagtg gtgacgtgcc
    70681 tgcggaaatg gctaagatgc gcgtgttaga acttgatttg atgaatgtcg ttgcagggac
    70741 acgcttccgt ggtgactttg aagaacgcat gaataatatc atcaaggata ttgaagaaga
    70801 tggccaagtc atcctcttta tcgatgaact ccacaccatc atgggttctg gtagcgggat
    70861 tgattcgact ctggatgcgg ccaatatctt gaaaccagcc ttggcgcgtg gaactttgag
    70921 aacggttggt gccaccactc aggaagaata tcaaaaacat atcgaaaaag atgcggctct
    70981 ttctcgtcgt ttcgctaaag tgacgattga agaaccaagt gtggcagata gtatgactat
    71041 tttacaaggt ttgaaggcga cttatgagaa acatcaccgt gtacaaatca cagatgaagc
    71101 ggttgaaaca gcggttaaga tggctcatcg ttatttaacc agtcgtcact tgccagactc
    71161 tgctatcgac ctcttggacg aagcagcagc aacagtgcaa aataaggcaa agcatgtaaa
    71221 agcagacgat tcagatttga gtccagctga caaggccctg atggatggca agtggaaaca
    71281 ggcagcccag ctaatcgcaa aagaagagga agtacctgtc tacaaagact tggtgacaga
    71341 gtctgatatt ttgaccacct tgagtcgctt gtcaggaatc ccagttcaaa aactgactca
    71401 aacggatgct aagaagtatt taaatcttga agcagaactc cataaacgtg tcatcggtca
    71461 agatcaagct gtttcaagta ttagtcgtgc cattcgccgt aatcagtcag gaattcgcag
    71521 tcacaagcgt ccgatcggtt cctttatgtt cctaggaccc acaggtgtcg gtaagaccga
    71581 gttggccaag gctttggcag aagttctctt tgatgacgaa tcagccctta tccgctttga
    71641 tatgagtgag tatatggaga aattcgcagc cagccgtcta aatggagctc ctccaggcta
    71701 tgtgggttac gaagaaggtg gggagctgac agagaaggtt cgcaataaac cctattccgt
    71761 tctcctcttt gatgaggtag agaaggccca cccagatatc tttaatgttc tcttgcaggt
    71821 tctggatgac ggtgtcttga cagatagcaa gggacgcaag gtcgattttt caaataccat
    71881 tatcattatg acatcgaatc taggtgcgac tgcccttcgt gatgataaga ctgttggttt
    71941 tggggctaag gatattcgtt ttgaccagga aaatatggaa aaacgcatgt ttgaagaact
    72001 gaaaaaagct tatagaccgg aattcatcaa ccgcattgat gagaaggtgg tcttccatag
    72061 cctatctagt gaccatatgc aggaagtggt gaagattatg gtcaagcctt tagtggcaag
    72121 tttggctgaa aaaggcattg acttgaaatt acaagcttca gctctgaaat tgttagcaaa
    72181 tcaaggatat gacccagaga tgggagctcg cccacttcgc agaaccctgc aaacagaagt
    72241 ggaggacaag ttggcagaac ttcttcttaa gggagattta gtggcaggca acacacttaa
    72301 gattggtgtc aaagcaggcc agttaaaatt tgatattgca taaaagaata aaagtatcag
    72361 catctgacca taagtcacag tggagtgaaa ctcaatgaaa atcaaagagc aaactaggca
    72421 gctagctgca ggttgctcaa aacactgttt tgaggttgca gatagagctg acgtggtttg
    72481 aagagatttt cgaagagtat gaaactaaaa cctatagctt ctaaacgatc cgtggttttc
    72541 accattcaac acaaaattca tatgtttatt accctccgtc gtatttgtct tagagcgtgt
    72601 gtagtagaaa aagagcagtc ttatctgaaa tttttattct ttcaaaagag acctgtttct
    72661 tttttgcatg tcaaatccgt tctagctggt atttgaaaaa tcaaactaat attcaatgaa
    72721 aatcaaagaa caaactagga agctagccgc aggttgctca aaacactgtt ttgaggttgt
    72781 agatagagct gacgtggttt gaagagtata agctgcaaga tgaatgattt tcttgtattg
    72841 acgttgttgt tgacaaaaag tagcggataa atgaaatcca ttccattatc atagatgata
    72901 ggctggtagg aaattttcaa atagcataca ggaaatagat gtatggagtt ctggtagtag
    72961 aaagggagag agatgaacat tttagttgca gatgacgagg aaatgattag agaaggaatt
    73021 gcagcatttc tgacagaaga gggttatcat gtcattatgg ctaaggatgg acaagaggtc
    73081 ttggaaaaat ttcaagatct ccctatccat ctcatggtac tggatttaat gatgcctagg
    73141 aagagtggtt ttgaagtgtt aaaagaaatc aatcaaaagc acgatattcc tgtcatcgtc
    73201 ttgagtgctc tgggagatga aactactcag tcacaggtat ttgatctcta tgctgatgat
    73261 catgtgacaa aacctttttc tttggtactg cttgtcaagc gtattaaggc gcttatcaga
    73321 cgttactacg tcatagagga tctttggcga tatcaggatg taacagtgga ttttacctct
    73381 tacaaagcac attataaaaa tgaagaaatt gatctcaaac caaaggaatt actggtacta
    73441 aagtgtttga ttcagcataa aaatcaagtt ttaagtagag agcagatatt ggaagaaatt
    73501 tcaaaagatg tagctgattt accttgtgat agggtcgttg atgtctatat tcgtactctt
    73561 cgcaaaaaat tagctttaga ttgtatcgtg actgtgaaaa atgttgggta taagattagc
    73621 ttatgataaa aaatcctaaa ttattaacca agtctttttt aagaagtttt gcaattctag
    73681 gtggtgttgg tctagtcatt catatagcta tttatttgac ctttcctttt tattatattc
    73741 aactggaggg ggaaaagttt aatgagagcg caagagtgtt tacggagtat ttaaagacta
    73801 agacatctga tgaaattcca agcttactcc agtcttattc aaagtccttg accatatctg
    73861 ctcaccttaa aagagatatt gtagataagc ggctccctct tgtgcatgac ttggatatta
    73921 aagatggaaa gctatcaaat tatatcgtga tgttagatat gtctgttagt acagcagatg
    73981 gtaaacaggt aaccgtgcaa tttgttcacg gggtagatgt ctacaaagaa gcaaagaata
    74041 ttttgctttt gtatctccca tatacatttt tggttacaat tgctttttcc tttgtttttt
    74101 cttattttta tactaaacgc ttgctcaatc ctctttttta catttcagaa gtgactagta
    74161 aaatgcaaga tttggatgac aatattcgtt ttgatgaaag taggaaagat gaagttggtg
    74221 aagttggaaa acagattaat ggtatgtatg agcacttgtt gaaggttatt catgagttgg
    74281 aaagtcgtaa tgagcaaatt gtaaaattgc aaaatcaaaa ggtttccttt gtccgcggag
    74341 catcacatga gttgaaaacc cctttagcca gtcttagaat tatcctagag aatatgcagc
    74401 ataatattgg agattacaaa gatcatccaa aatatattgc aaagagtata aataagattg
    74461 accagatgag ccacttattg gaagaagtac tggagtcttc taaattccaa gagtggacag
    74521 agtgtcgtga gaccttgact gttaagccag ttttagtaga tattttatca cgttatcaag
    74581 aattagctca ttcaataggt gttacaattg aaaatcaatt gacagatgct accagggtcg
    74641 tcatgagtct tagggcattg gataaggttt tgacaaacct gattagtaat gcaattaaat
    74701 attcagataa aaatgggcgc gtaatcatat ccgagcaaga tggctatctc tctatcaaaa
    74761 atacatgtgc gcctctaagt gaccaagaac tagaacattt atttgatata ttctatcatt
    74821 ctcaaatcgt gacagataag gatgaaagtt ctggtttggg tctttacatt gtgaataata
    74881 ttttagaaag ctatcaaatg gactatagtt ttctccctta tgaacacggt atggaattta
    74941 agattagctt gtagacagat tagtttttta ttaaagttca tatagggtta acataagtgt
    75001 gttattcttt gtatagataa aagaaaggat actaatatgg tattagcgat tattttagta
    75061 acattcctta ttcgattgat ttttttaaag cgttcgatag agaatgagaa acgaatcctt
    75121 agcaatggcg ggaaagaatt tggagttgag aatacaaaac gattaactat ggctcatatt
    75181 gttttttatc tctcttgctt ggttgaggca atggtgcaca agacaatttt tgatggcatg
    75241 ggcatggttg gtttagtctt gcttattttt tctatgctga tgttgatgtt ggtgattcac
    75301 ttgttgggag atatttggac agtgaagctt atgcttgtca ataatcacaa atatgtagat
    75361 catatcttgt ttaggacagt aaaacatcct aattactttt taaatattct tcctgagttg
    75421 attggcttga ccttgttgag tcatgcttat gtgacttttg ttttagtttt tccagtttat
    75481 gcagttattt tgtatcgacg aatagctgaa gaggaaaagc tattacatga agttataatc
    75541 ccaaatggaa gcataaagag ataaatacaa aattcgattt atatacagtt catattgaag
    75601 taatatagta atagacttca tgcgaaacaa aatatggtac aatagttcta tgaattatga
    75661 agcaaggttg agaatatttt tgccaaagta aaaacgttta aaatgttttc aacaacctat
    75721 cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctggcat tatcaatcat
    75781 gaactaggat tctagttttg caggaagtct aatgttaaga aaaatattgg agaaaataaa
    75841 catgtttgca tcaaaaagcg aaagaaaagt acattattca attcgtaaat ttagtattgg
    75901 agtagctagt gtagtagttg ctagcttgtt cttaggagga gtagttcatg cagaagaggt
    75961 tggtggtagg aataccccca cggttacatc tagtgggcaa gatatatcga agaagtatgc
    76021 tgatgaagtc aagtcgcatc tagaagaaat gtttagtggg atccaattag atagaagaaa
    76081 acatacccaa aatttcaact ttaacctaaa gttgagcaaa attcaaacga agtatttgcg
    76141 tgaattaagt gttttaaagt cgaaatctga gttgacgtta gaaacaaaag aagagttgct
    76201 gtcaaaaacc aaagcagagt tagacgcagc ttttgagcag tttaaaaaag atacattgaa
    76261 actaggagaa aaggtagcag aagctgagaa gaaggttgaa gaagctaaga aaaaagccaa
    76321 ggctcaaaaa gaagaagatc accgtaacta cccaaccaat acttacaaaa cgcttgaact
    76381 tgaaattgct gagtccgatg tgaaagttaa agaagcggag cttgaactat tgaaagagga
    76441 agctcaaact cgaaacgagg acacaattaa ccaagcaaaa gcgaaagtta agagtgaaca
    76501 agctgaggct acaaggttaa aaaaaatcaa gacagatcgt gaagaagcag aagaagaagt
    76561 taaagataaa ccaaagaagc ggacaaaacg aggagctctt ggagagccag caacacctga
    76621 taaaaaagaa aatgatgcga agtcttcaga ttctagcgta ggtgaagaaa ctcttccaag
    76681 cccatccctg aaaccaggaa aaaaggtagc agaagctgag aagaaggttg cagaagctga
    76741 gaaaaaagcc aaggctcaaa aagaagaaga tcgccgtaac tacccaacca atacttacaa
    76801 aacgcttgaa cttgaaattg ctgagtccga tgtggaagtt aaaaaagcgg agcttgaact
    76861 agtaaaagag gaagctaaga aacctttaaa cgagggcaca attaagcaag caaaagcgga
    76921 agttgagagt aaaaaagctg aggctacaag gttagaaaaa atcaagacag atcgtaaaaa
    76981 agcagaagaa gaagctaaac gaagagcagc agaagaagat aaagttaaag aaaaaccagc
    77041 tgaacaacca caaccagcgc cggcccctca accagaaaaa ccaactgaag agcctgagaa
    77101 tccagttcca gctccaaaac cagagaagcc agctgaacaa ccaaaaccag agaagccagc
    77161 tgaacaacca aaagcagaaa aaacagatga tcaacaagct gaagaagact atgctcgtag
    77221 atcagaagaa gaatataatc gcttgactca acagcaaccg caaaaaccag agcaaccagc
    77281 tcctgcacca aaaataggct ggaaacaaga aaacggtatg tggtacttct acaatactga
    77341 tggttc
//
LOCUS       DAVDHC010000008        75674 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVDHC010000008 DAVDHC010000000
VERSION     DAVDHC010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.008"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            145..6846
                     /locus_tag="VUR43_000734"
     CDS             145..6846
                     /locus_tag="VUR43_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET5412456.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSL
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTNLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLKGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQIFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAKLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDSYETKDLTVEWEEVPAEN
                     LTKAGQFTIRGRVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7094..7950)
                     /locus_tag="VUR43_000735"
                     /pseudo
     CDS             complement(7094..7950)
                     /locus_tag="VUR43_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8160..8519)
                     /locus_tag="VUR43_000736"
     CDS             complement(8160..8519)
                     /locus_tag="VUR43_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET5412457.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8611..9567
                     /locus_tag="VUR43_000737"
                     /pseudo
     CDS             8611..9567
                     /locus_tag="VUR43_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9551..10108
                     /locus_tag="VUR43_000738"
     CDS             9551..10108
                     /locus_tag="VUR43_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5412458.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10101..10355
                     /locus_tag="VUR43_000739"
     CDS             10101..10355
                     /locus_tag="VUR43_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412459.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10367..12421
                     /locus_tag="VUR43_000740"
     CDS             10367..12421
                     /locus_tag="VUR43_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET5412460.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12600..13460
                     /locus_tag="VUR43_000741"
     CDS             12600..13460
                     /locus_tag="VUR43_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET5412461.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13671..14381
                     /gene="ccdA2"
                     /locus_tag="VUR43_000742"
     CDS             13671..14381
                     /gene="ccdA2"
                     /locus_tag="VUR43_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET5412462.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14401..14967
                     /locus_tag="VUR43_000743"
     CDS             14401..14967
                     /locus_tag="VUR43_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET5412463.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14978..16090
                     /gene="msrB"
                     /locus_tag="VUR43_000744"
     CDS             14978..16090
                     /gene="msrB"
                     /locus_tag="VUR43_000744"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET5412464.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            16403..17140
                     /locus_tag="VUR43_000745"
     CDS             16403..17140
                     /locus_tag="VUR43_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5412465.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIDQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGENR"
     gene            17137..18828
                     /locus_tag="VUR43_000746"
     CDS             17137..18828
                     /locus_tag="VUR43_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5412466.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            18944..19507
                     /locus_tag="VUR43_000747"
     CDS             18944..19507
                     /locus_tag="VUR43_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET5412467.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            19529..25231
                     /locus_tag="VUR43_000748"
     CDS             19529..25231
                     /locus_tag="VUR43_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET5412468.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEV
                     VPDDTKYVDEEVVERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPVVPKVVKKG
                     TKPVEGTAVETREEVIPFATKEQEDGTLKRGTRQVAQEGVNGKKQITETYKTIRGEKT
                     NEAPTVEETVLQAPQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVE
                     IKSIKVALKDNTGTVIKEVTVEENNLNVTLDNLKYYQGYTLSTTMVYNRGEGEETETL
                     EDKEVQLDLKKVEIKNIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKV
                     TRLAVDKIEEVEEDGKTLYKVTAKAPDLVQRNADNTLSEEYVHYFEKQLPKIGNVYYN
                     FNELITDMQKTPNGEFKLGADLNAVNVPTPNKSYVTAKFTGKLYSEGDKHYTIHNLAR
                     PLFAQAENAHIHDINLGNVNINMPWANKTAPLGEMFKKSTIENVKVTGNVVGNNDVTG
                     MVNKLDESDMRNVAFIGNITSVGSAGWWSGGLVSESWRSNTDNSYIDTTIKGNKAKVG
                     GLIAKLNHGADPRDVGARGRLKNSVAKGTIDVRDPQETGGLLHSNWSWGLAENNITMM
                     KVKNGGEILYGSRDAEDDDYFGANWVRNNNAFVNGISEGKQSYSRSSRWKGISEDEAK
                     TRIAKMGITAHEYEITQHLTDKLNRAAFKEDTYKTTQDYKTERELAYRNIEKLQPFYN
                     KEWIINQGNKLTDGSNLMIKEVLSVIGMKNGQFVTDLSDIDKIMIHYADGTKEEKTVT
                     RKADSKVQQIREYSVEGLGDVVYTPNMVEKDRAQLITDIKAKLDSVQLISPEVRNLMD
                     KRGKAHENTDERRNGYIRNLFLEESLDEVKGNLDKLVKALVENEDHQLNGDEAAMKAL
                     VKKVEDNKAKIMLGLAYLNRYYGFKYDEKSMKDIMMFKPDFYGKNVSVLDFLIRVGSR
                     EHNIKGNRTLEAYREVIGGTIGIGELNGFLNYNMRLFTEETDINTWYKKAVSHTNYIV
                     EKQSSNPAFANKKYRLYENLNNGEHGKYILPLLTTKKAHMFLISTYNTLAFSAFEKYG
                     KNTEAEREAFKKEIDLRAQEQINYLDFWSRLAADNVRDRLLKSENMVPSAIWDNQEVP
                     GHGWADRMGHNKNGDYAPVREFYGPTGKWHGYNGTGAYAYIFTNPQNSEAVYYIISSL
                     ISDFGTSAFTHETTHINDRMAYLGGWRHREGTDVEAFAQGMLQSPAVSSPNGDYGALG
                     LNMAYKRENDGNQWYNYDSNKLDSRAKIDHYMKNYNEALMMLDHLEADAVIAKNNGDN
                     NKWFKKMDKKWRENANRNGLVGQPHQWDLLRDLNEEENKKKLTSIDDLVDGNYVTKHN
                     MPGNKHYRAEGFDTAYQTVNMMAGIYGGNTSKSAVGSISFKHNTFRMWGYFGYLDGFV
                     GYASNKYKDAANKENKGLLGDDFIIKKVSDGKFDSLEAWKKEWFKEVKAKGEKGFVAI
                     EIDGKTITNYAELRELFDKAVEADLKAGNSNQTVALKEKVYKQLLQKSDGFVGNLFKA
                     "
     gene            25306..27027
                     /gene="pabB"
                     /locus_tag="VUR43_000749"
     CDS             25306..27027
                     /gene="pabB"
                     /locus_tag="VUR43_000749"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET5412469.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            27028..27645
                     /locus_tag="VUR43_000750"
     CDS             27028..27645
                     /locus_tag="VUR43_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5412470.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            27695..28685
                     /locus_tag="VUR43_000751"
                     /pseudo
     CDS             27695..28685
                     /locus_tag="VUR43_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            28820..29779
                     /locus_tag="VUR43_000752"
     CDS             28820..29779
                     /locus_tag="VUR43_000752"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET5412471.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            29877..30716
                     /locus_tag="VUR43_000753"
     CDS             29877..30716
                     /locus_tag="VUR43_000753"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET5412472.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(30764..30934)
                     /locus_tag="VUR43_000754"
     CDS             complement(30764..30934)
                     /locus_tag="VUR43_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET5412473.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            31055..31939
                     /gene="miaA"
                     /locus_tag="VUR43_000755"
     CDS             31055..31939
                     /gene="miaA"
                     /locus_tag="VUR43_000755"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET5412474.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPYEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            31932..33170
                     /gene="hflX"
                     /locus_tag="VUR43_000756"
     CDS             31932..33170
                     /gene="hflX"
                     /locus_tag="VUR43_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET5412475.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            33163..33786
                     /locus_tag="VUR43_000757"
     CDS             33163..33786
                     /locus_tag="VUR43_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET5412476.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            33801..34730
                     /locus_tag="VUR43_000758"
     CDS             33801..34730
                     /locus_tag="VUR43_000758"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET5412477.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            34751..35506
                     /locus_tag="VUR43_000759"
     CDS             34751..35506
                     /locus_tag="VUR43_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET5412478.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(35560..36468)
                     /locus_tag="VUR43_000760"
     CDS             complement(35560..36468)
                     /locus_tag="VUR43_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET5412479.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            36532..36801
                     /locus_tag="VUR43_000761"
     CDS             36532..36801
                     /locus_tag="VUR43_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET5412480.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            36801..37181
                     /locus_tag="VUR43_000762"
     CDS             36801..37181
                     /locus_tag="VUR43_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5412481.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            37299..37496
                     /locus_tag="VUR43_000763"
     CDS             37299..37496
                     /locus_tag="VUR43_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412482.1"
                     /translation="MGILSIILGLLFPIVGLILGIIGLVLAISYQKESQLDYKIEKIL
                     NILGIVISVVNWIVAIALIFR"
     gene            complement(37536..38261)
                     /locus_tag="VUR43_000764"
     CDS             complement(37536..38261)
                     /locus_tag="VUR43_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET5412483.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            38423..40264
                     /gene="typA"
                     /locus_tag="VUR43_000765"
     CDS             38423..40264
                     /gene="typA"
                     /locus_tag="VUR43_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET5412484.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            40284..40538
                     /locus_tag="VUR43_000766"
     CDS             40284..40538
                     /locus_tag="VUR43_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET5412485.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            40902..41201
                     /locus_tag="VUR43_000767"
     CDS             40902..41201
                     /locus_tag="VUR43_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET5412486.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            41272..43291
                     /locus_tag="VUR43_000768"
                     /pseudo
     CDS             41272..43291
                     /locus_tag="VUR43_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            43293..43934
                     /locus_tag="VUR43_000769"
     CDS             43293..43934
                     /locus_tag="VUR43_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412487.1"
                     /translation="MIELKNISKKFGSRQLFSDMNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            44038..45390
                     /locus_tag="VUR43_000770"
     CDS             44038..45390
                     /locus_tag="VUR43_000770"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET5412488.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVIPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELAIQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            45392..46450
                     /locus_tag="VUR43_000771"
     CDS             45392..46450
                     /locus_tag="VUR43_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET5412489.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            46460..47626
                     /gene="divIB"
                     /locus_tag="VUR43_000772"
     CDS             46460..47626
                     /gene="divIB"
                     /locus_tag="VUR43_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET5412490.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKATIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESN"
     gene            47892..48593
                     /gene="pyrF"
                     /locus_tag="VUR43_000773"
     CDS             47892..48593
                     /gene="pyrF"
                     /locus_tag="VUR43_000773"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET5412491.1"
                     /translation="MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGAAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            48627..49259
                     /locus_tag="VUR43_000774"
     CDS             48627..49259
                     /locus_tag="VUR43_000774"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET5412492.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            49439..49842
                     /locus_tag="VUR43_000775"
                     /pseudo
     CDS             49439..49842
                     /locus_tag="VUR43_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            49938..50702
                     /locus_tag="VUR43_000776"
     CDS             49938..50702
                     /locus_tag="VUR43_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412493.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STVIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSAHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            50702..51454
                     /locus_tag="VUR43_000777"
     CDS             50702..51454
                     /locus_tag="VUR43_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412494.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            51464..52162
                     /locus_tag="VUR43_000778"
     CDS             51464..52162
                     /locus_tag="VUR43_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412495.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            52159..52806
                     /locus_tag="VUR43_000779"
     CDS             52159..52806
                     /locus_tag="VUR43_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412496.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(52886..53751)
                     /locus_tag="VUR43_000780"
                     /pseudo
     CDS             complement(52886..53751)
                     /locus_tag="VUR43_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(53763..54521)
                     /locus_tag="VUR43_000781"
                     /pseudo
     CDS             complement(53763..54521)
                     /locus_tag="VUR43_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(54522..55439)
                     /locus_tag="VUR43_000782"
     CDS             complement(54522..55439)
                     /locus_tag="VUR43_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET5412497.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFG
                     LARNFNINISGETSVIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFW
                     IYGTILILYFAVCYPISKLSTHLEKHWRN"
     gene            55472..55618
                     /locus_tag="VUR43_000783"
     CDS             55472..55618
                     /locus_tag="VUR43_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET5412498.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            55746..57236
                     /gene="lysS"
                     /locus_tag="VUR43_000784"
     CDS             55746..57236
                     /gene="lysS"
                     /locus_tag="VUR43_000784"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET5412499.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            57861..58997
                     /gene="lctO"
                     /locus_tag="VUR43_000785"
     CDS             57861..58997
                     /gene="lctO"
                     /locus_tag="VUR43_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET5412500.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      59251..59339
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            59554..60222
                     /locus_tag="VUR43_000786"
     CDS             59554..60222
                     /locus_tag="VUR43_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET5412501.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KILKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            60510..61292
                     /gene="thiM"
                     /locus_tag="VUR43_000787"
     CDS             60510..61292
                     /gene="thiM"
                     /locus_tag="VUR43_000787"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET5412502.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            61294..61923
                     /locus_tag="VUR43_000788"
     CDS             61294..61923
                     /locus_tag="VUR43_000788"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET5412503.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      62132..62220
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            62482..63042
                     /locus_tag="VUR43_000789"
     CDS             62482..63042
                     /locus_tag="VUR43_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5412504.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            63043..64428
                     /locus_tag="VUR43_000790"
     CDS             63043..64428
                     /locus_tag="VUR43_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412505.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHGQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            64430..65080
                     /locus_tag="VUR43_000791"
     CDS             64430..65080
                     /locus_tag="VUR43_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET5412506.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            65091..65783
                     /gene="tenA"
                     /locus_tag="VUR43_000792"
     CDS             65091..65783
                     /gene="tenA"
                     /locus_tag="VUR43_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET5412507.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            65788..66312
                     /gene="thiW"
                     /locus_tag="VUR43_000793"
     CDS             65788..66312
                     /gene="thiW"
                     /locus_tag="VUR43_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET5412508.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            66312..67115
                     /locus_tag="VUR43_000794"
     CDS             66312..67115
                     /locus_tag="VUR43_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET5412509.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            67108..67740
                     /locus_tag="VUR43_000795"
     CDS             67108..67740
                     /locus_tag="VUR43_000795"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET5412510.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(67949..68755)
                     /gene="thiD"
                     /locus_tag="VUR43_000796"
     CDS             complement(67949..68755)
                     /gene="thiD"
                     /locus_tag="VUR43_000796"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET5412511.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCT
                     FAAVITAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(68839..68937)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            69121..69516
                     /locus_tag="VUR43_000797"
     CDS             69121..69516
                     /locus_tag="VUR43_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET5412512.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            69527..69898
                     /locus_tag="VUR43_000798"
     CDS             69527..69898
                     /locus_tag="VUR43_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET5412513.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            69908..72151
                     /locus_tag="VUR43_000799"
     CDS             69908..72151
                     /locus_tag="VUR43_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET5412514.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            72358..74133
                     /gene="spxB"
                     /locus_tag="VUR43_000800"
     CDS             72358..74133
                     /gene="spxB"
                     /locus_tag="VUR43_000800"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET5412515.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            74244..74591
                     /locus_tag="VUR43_000801"
     CDS             74244..74591
                     /locus_tag="VUR43_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5412516.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(74708..75619)
                     /locus_tag="VUR43_000802"
                     /pseudo
     CDS             complement(74708..75619)
                     /locus_tag="VUR43_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        22897 a        13905 c        16759 g        22113 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgctgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caagcttcaa gtcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ctttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgcagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatacgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cttttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcatcagc aacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt cagattatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt gttcttgaat ggaaaatctc ttggtcttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccaggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc acccttactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaag aaagaaggac aagaaaagac tgttttgggg
     3121 acagaggtgc caaaagtaca gaccattatt ggagaggcac ctgaaatgcc taccactgtt
     3181 ccgtttgtat acagtgatgg tagtcgtgca gaacgtcctg taacctggtc tttagtagat
     3241 gtgagcaagc ctggtattgt aacggtgaaa ggtatggctg acggacgaga agtagaagct
     3301 cgtgtagaag tgattgctct taaatcagag ctaccagttg tgaaacgtat tgctccaaat
     3361 actaacttga attctgtaga caaatctgtt tcctatgttt tgactgatgg aagtgtacaa
     3421 gagtatgaag tggacaagtg ggagattgcc gaagaagata aagctaagtt agcaattcca
     3481 ggttctcgta ttcaagcgac cggttattta aaaggtcaac caattcatgc aacccttgtg
     3541 gtagaagaag gcaatcctgc agcacctgta gtgccaactg ttactgttgg aggtgaagca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ttgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggccc tcttcaaacc
     3781 tatgcaattc aattccttga agaagcgcca aaaattgctc acttgagctt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgat aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctgaac
     4021 gctgaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca ggaaccaagt
     4141 cttccagcaa cagtaacagt tgagtatgac aaaggtttcc ctaaaactca taaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa tatttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtcca
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaagg tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtagtaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggcaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctaaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa gcaaggacaa
     5101 acaagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg atatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acagctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagcg gaaaatctga caaaagcagg tcaatttact
     5521 attcgaggcc gtgtccttgg tagtgacctt gttgctgagg tcactgtacg agtgacagac
     5581 aaacttggtg aggctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa caaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtcac caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgct
     5821 caagccaaac ttcacttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagcagat aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac caagtgaatt gcctcaagaa agcacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc acttgactaa ggaaaaacca gtttctgaga agacagttgc tgctgtacaa
     6421 gaagatcttc caaaactcga atttgttgaa aaagatttgg cctacaagac agttgagaaa
     6481 aaagattcaa cactgtatct aggtgaaact cgtgtagaac aagaaggaaa aactggtaaa
     6541 gaacgtatct ttacagcgat taatcctgat ggaagtaagg aagaaaaact ccgtgaagtg
     6601 gtagaagctc cgacagaccg catcgtcttg gttggaacca aaccagtagc tcaagaagct
     6661 aaaaaaccac aagtgtcaga aaaagcagat acaaaaccaa ttgattcaag tgaagctagt
     6721 caaactaata aagcccagtt accaaataca ggtagtgcgg caagccaagc agcagtagca
     6781 gcaggtttag ctcttctagg tttgagtgca ggattagtag ttactaaagg taaaaaagaa
     6841 gactagaaat tttgatacct tctttatcat taaagaccaa agaaaaactc ttgtcctaaa
     6901 tagaagataa agagtctgga acaaaatagt tctcaaccac aaaaaagcta gatatttcca
     6961 attgcggaac tctagctttt taattttgag tcgttctctt attgtatagt agattgaaac
     7021 tagagtagta cacttctact tctaaaacat tgttagaaat cgatttgact gtccttatcg
     7081 atttgtcctg ttcttatttc atttcactat gttttaggag gttattggcc ataagtacca
     7141 atcccatgtc aattctcact tgacgcttcc ctctcagatt acatctcttg taacccaaac
     7201 aagcctttat ctgcccaaag acaggttcca catcaatctt gcgttgagcg aaaatctgtc
     7261 tatcttgggg agataaaagc gcctgacatt ctttagcttt caagttttga tagcgttcgt
     7321 tcatatacag tcccttttga ggggctgatt caggttcatc agcgtagtaa accttgattt
     7381 cctgttgaaa gtctgtctgt gttttctggt acttgatatg gtgaaaacga tagcaccagc
     7441 catcaggatg tatgtagcta tcctccttgt cattatagtg ccaattcgct aagtttttag
     7501 ctgactgttt ataccctctc ttttgtttct tatcaaacat ggcatattta atcagaaggg
     7561 gagtgatttc ttcttgaaaa tagacttgta tctgttcttg aagcttggcg gagaatttct
     7621 ctgtcgtttt cttccacaca aaactatact tgttggcatt ggcttcaatc ttagttccgt
     7681 caataaacaa acaatctaag gtcactaact cttccatttt tcaatttttc gaccagagaa
     7741 aatcccttgt gaataggcaa atagaagagt agatacaagc attttagggt gataagacgg
     7801 gcgaccaaag gcatgataga aggcgtagaa gtgacgttcc tccaaggtat tcaccacttt
     7861 ttcaatagta aagacgagat ggtcttgtgg taagaaggaa ctgatttcta gtggtaaagt
     7921 tgtttgattt gtgttatagt gaatatgcat gggatagcct ttctaaatgg tttattaagc
     7981 aattctattt taccaagact atcgtaacca tgcaaaaaag caacggcaaa tccgttgcct
     8041 ttttggatat aagagactat tgtcccagac tcttttcttt gtataaaatt gtatagtgtt
     8101 attgtctata ctattttgta gagaaagcaa aaatccctag aaaatgctta gggattcgac
     8161 tatttcatta agaacaattc aacaatcatt tctatataca tgataagggt taataagaat
     8221 cctgcacgcc agaagaattt gatgaattta ggatagtaaa agctgcgttt tttcaaaagg
     8281 aagaaaaaga cgagaataat ggctaggaac gagagggcta gccccagtct agggaggaaa
     8341 ttatgggtaa aggttttagc tgtaatcaag taatactcaa ataccaagac tggaaaagcc
     8401 aaatccgcaa agtttcgtcc tagttttttt aatctaaaaa gtttggttag gataatgcag
     8461 acgactaagg tcagtatcaa taataaaata gatgctaatt tcattaaaat catacccata
     8521 ttgtatcata aaaaaaggct aatggaaacg agaaacagag gaatttatag gaaagtcagg
     8581 cttttgagat tgtgggtgat ttttgttata atgaaagtta taaaatctta taataccttg
     8641 aatgattatt atcgaaaact ctttggagaa aagactttta aagtccctat tgatgcggga
     8701 tttgactgtc ccaatcgtga tggaactgtg gctcatggag gctgtacttt ttgtacggtt
     8761 tccggttctg gagatgccat tgtggcacca gatgcgccta tccgtgagca attttataag
     8821 gaaattgact ttattcatcg taagtggcca gatgttcaga agtatctggt ttattttcaa
     8881 aattttacca acacccatga aaaggtggaa gttattcgag agcgttatga acaggctatc
     8941 aatgagccag gtgtggtagg aatcaatatt ggaacgcgcc cagactgttt accagacgaa
     9001 accatcgaat atttggctga gttatcggag tgcatgcatg tgacggttga attgggcttg
     9061 caaactactt atgaagcaac ctctgacctg attaaccgtg cgcattctta tgaattgtag
     9121 gtggaaacgg tcaagcgttt gagaaagtat ccaaaaattg agattgtttc ccatttgatc
     9181 aatggtttgc ctggtgaaac ccatgagatg atggttgaaa atgtccgccg ttgtgtcacg
     9241 gataacgata ttcaagggat taaactgcat ttgctccatc ttatgacaaa tactcgtatg
     9301 caacgagatt accatgaggg gcgtttacaa ttgatgagtc aggacgaata tgtcagggtc
     9361 atctgtgacc aactggaaat tattcccaaa catatcgtca tccatcgaat tacaggagat
     9421 gcgcctaggg atatgctgct tgggcctatg tggagcctca ataaatggga agctctcaac
     9481 agcattgaga tggagatgcg acgtcgtgga agtgttcaag gatgcaaggc tgtaaaacag
     9541 gagtttgaaa atgaaaagac cacttgagat ggcacatgat tttttggctg aggtcgtgac
     9601 aaaagaggat gtcgtagtgg atgcgactat gggaaatggt catgacacgc tttttttagc
     9661 caagctagcc aagcaagtct atgcctttga tattcagaag caagccttgg aaaagaccca
     9721 agagcgtttg catcaggctg acttgacaaa tgcccagtta atcttgcaag gccatgagac
     9781 actggaccag tttgtgataa aagctaaggc agggattttt aatctgggct atttgccgtc
     9841 agctgataag tctgtcatca cccgaccgca gacaacgatt gaggcattag aaaagctatg
     9901 tggcttactt gtcaaaggtg gacgaattgc tattatgatt tactatggtc atgaaggagg
     9961 cgatctcgag agagatgctg tcttggattt tgtgatccag ttgaaccaac aagagtacac
    10021 agctgccatt taccgaactt taaaccaagt caacaacccg ccgtttttag tgatgattga
    10081 aaaattagag agatacagac atggataaac aatacctaca cgaaaagctg gatgccatgc
    10141 gccagaattt tgttgaatca acccaccacg aacgatcggt gggcgtgcta gaccaagcgc
    10201 atatgagcaa aaaaatgctt aaaatcaaga aaaaattagt tgctcttgaa atggaacggt
    10261 gccagagaaa aattgagcac aaagactgtt ccaagattga ccaaaaaatc aaagagcaga
    10321 aggagatatt tgaatcctgt tgtaaaaaag attaaggagg acgtgcgtgg aattactgat
    10381 ttacctcatc ctatttttac tggttttgat tgtctcaagt acaaccaata agctcctgcc
    10441 ctttttgcct ctccctttgg tgcagattct tttgggaatt gtgattggtc tctttttacc
    10501 caatactgac tttcacctta atacggagtt gtttttggca ctggttatcg gacccttgct
    10561 tttccgagag gctgaagaag cagatgttac ggctatttta aaacactggc gaatcattgt
    10621 ttatctcata tttccagtga tttttatctc gaccttgagt ttgggtggct tggcccatct
    10681 tctttggttc agccttccct tggcagcttg cttggctgtt ggggcagccc ttggtcctac
    10741 ggacttggtg gcctttgcct ctctttcgga gcgttttagc tttcctaagc gcgtgtccaa
    10801 tattcttaag ggcgaaggac tcttgaatga tgcttctggt ttggtggctt ttcaggtagc
    10861 tttgacagct tggacaactg gagctttttc tctggggcaa gctagcagtt cgctcatctt
    10921 ttcaatccta ggcggttttt taattggatt tttaacggcc atgaccaacc gcttcctcca
    10981 taccttcttg ctaagtgtgc gcgcaacgga tattgccagt gaacttttat tagaattgag
    11041 tttgcctcta gtgaccttct ttctggcaga agaagttcat gtttcaggta ttattgccgt
    11101 cgtagttgct ggaattttaa aggcaagtcg cttcaagaaa atcacgctcc tcgaagccca
    11161 agtggatacg gtgaccgaga cggtctggca tacagtgacc tttatgctca acggttctgt
    11221 ctttgtgatt ttagggatgg agttggaaat gatagcagaa cctatcttga ccaatccaat
    11281 ctataatcct ctacttttat tgctatctct catcgccctt acctttgtcc tctttgtcat
    11341 tcgttttatt atgatctatg gctattatgc ctatagaacc cgacgcctca agaaaaagct
    11401 aaataagtat atgaaggaca tgtttctctt gaccttttca ggtgttaagg gaacggtgtc
    11461 gattgctacg attctcttga taccaagtaa tctagaacag gagtatcctc ttttgctttt
    11521 ccttgttgca ggtgtgacgc ttgtcagctt tttaacaggt ctcttggtct tgcctcatct
    11581 ttctgatgaa gaggaagaaa gcaaggatta tctcatgcat atcgccattt tgaatgaagt
    11641 aacgctagag ttggaaaaag agttggaaga caccagaaat aaacttcccc tctatgcggc
    11701 tattgacaat tatcatggac gtattgaaaa tctcatttta agccaagaaa accaggatga
    11761 tcaagaagat tgggctgctt tgaaactctt gattcttagt attgaaagtg atggtttgga
    11821 acaggcctat gaagagggga acattagcaa tcgtgcttac cgagtttacc aacgttatct
    11881 gaaaaatata gaacaaggaa tcaatcgtaa acttgcctca agactgacct attattttct
    11941 tgtttccttg aggattttac gttttctcct tcatgaagtt tttactcttg gaaagacctt
    12001 ccgtagctgg aaggacaagg agcaaagccg tctccgtgct cttgattatg accaaattgc
    12061 agagctctat cttgccaata cagagatgat tattgaaagt ttggaaaacc tgaagggagt
    12121 ctacagacgc tctttgatta gttttatgca ggagtctcgt cttcgagaaa cagctattat
    12181 cagcagtggt gcctttgtcg aacgggttat caatcgtgtc aaacccaaca atatcgatga
    12241 aatgctgaga ggctattatc tggagcgcaa gttgattttc gaatacgaag aaaaacgatt
    12301 gattacgact aagtatgcca agaaattacg acaaaatgta aataacttag agaactattc
    12361 cttgaaggaa gctgccaata ccctgccgta tgatatggtg gaattggtaa gaagaaatta
    12421 gttaatactc ttcgaaaatc tcttcaaacc acgtcagcgt cgccttggat tatatatgtg
    12481 actgacttcg tcagtttcat ctacaacctc aaagcagggc tttgagcaac ctgcggctag
    12541 cttcctagtt tgctctttga ttttcattga gtataagatt ataaatgaag gagtatgaca
    12601 tgaaaaagtg gtggaaagag ctgatagaca agcctttatt aaaagctttt ttgcattatt
    12661 atcaagcatc agatagtgag ttgaccagtg tcgcagtagc ctactattgg ttgatttcga
    12721 ttttccccct gcttttggtg gtggtcaata tcctccccta ttttcagatt cctgtgggag
    12781 aatttctgtg ctttatgaaa gacgttctgc ccccaagcct ctatgaaggt gtggaaaaaa
    12841 tagccagaga agttttgacg caaccttcaa caggtttatt gagtttttct gttttatcgg
    12901 cgttatggag tttttcaaaa tctatgaatt tcttgcaaaa agcttttaac aaggcttatg
    12961 gcgtcgaaaa gagtcgtgga cttatttccc atcagatgct aagtctccta gtcagttttg
    13021 gcttgcagct cctctttgcg tttgccttgt ttttgatctt atttggtcag atgattttgg
    13081 ctttacttgc tcattattgg acaaaagatg gcattatcta tcaggcttta caagggttgg
    13141 caggtcctct gatttacgcc ctcctctttg ctatcttggt catgctttat tattttcttc
    13201 ccaatctatc taacaggaaa attagctata ccctaccagg cagtgccttt gttctcttag
    13261 tgattttagg tttactaact ctgttctcta gttatctcaa ttactatgtc catcatttgg
    13321 tggatgtccg aattttaggt tccgttcttc ttgttgttat gatgttttgg tttatcttga
    13381 ttgctaaaat tgttatccta ggcgcggtta tcaatgccag tatgcagagt ttgaaagatc
    13441 cggtctttaa aaaagactaa ctatttatcc attacaaaag cgcatagtat caaaacttta
    13501 tagaaccttg atactatgcg cttttgtgct ttgacagttt tttgtatagt ttttgtccaa
    13561 gatttctaaa tcatctgatt aaattcctat tttcccctat cattgtccct gttttttcga
    13621 aaatggaagg agtataataa atctatcaat aaaatgatag gaggaacttt atgggtcata
    13681 ttttcttttt tctaagtgtc tttttggcag ggattctatc cttcttttct ccttgtatct
    13741 tacctttgtt accggtctat acaggagtgt tactagatga taaggatggt gctcaggctt
    13801 ctagcggcaa attttcaatc tcagttacta gtttattacg aactctggcc tttatagcag
    13861 gaatttcctt tatatttatt ttgttgggct atggagctgg ttttttaggc gatttgcttt
    13921 atgcttcttg gttccaatat cttactgggg caattattat ccttcttggt ttgcaccaaa
    13981 tggagattct acactttaag gggctttata aggaaaagag gctacaactg caaggacagg
    14041 ggcaaaatgg taagggctat agtcaggcat ttttattggg cttgaccttt agttttgctt
    14101 ggacgccttg cgtggggccg gttctagggt ctgttttggc cttggcggct tcaggtggtt
    14161 caggagcttg gcagggagct ggtctcatgt tggtgtatac gctgggcttg gcgctaccat
    14221 tcttgcttct agctctgacc tctagttatg ttttgaaaca tttccgaaaa cttcatccct
    14281 atctcggaat cctcaaaaaa gtgggtggtt ttctcattat tgtgatggga ctcttggttc
    14341 tgtttggaaa tgcttcaatt ttaagtcaat tatttgaata aaatggaaag gaatatcaat
    14401 atgaaaaaat ggcaaacatg tgttcttgga gcaggttcgc tcctttgttt gacggcttgt
    14461 tcaggcaagt ccgtgactag tgaacaccaa acgaaagatg aaatgaagac ggagcagaca
    14521 gctagtaaaa caagcgcagc taaagggaaa gaggtggctg attttgaatt gatgggagta
    14581 gatggcaaga cctaccgttt atctgattac aagggcaaga aagtctatct caaattctgg
    14641 gcttcttggt gttccatctg tctggctagt cttccagata cggatgagat tgctaaagaa
    14701 gctggtgatg actatgtggt cttgacagta gtgtcaccag gacataaggg agagcaatct
    14761 gaagcggact ttaagaattg gtataaggga ttggattata aaaatctccc agtcctagtt
    14821 gacccatcag gcaaactttt ggaaacttat ggtgtccgtt cttacccaac ccaagccttt
    14881 atagacaaag aaggcaagct ggtcaaaaca catccaggat tcatggaaaa agatgcaatt
    14941 ttgcaaactt tgaaggaatt agcctaggag gtgtcttatg aatgataagt taaaaatctt
    15001 cttgttgcta ggagtatttt ttctagccat aaccggtttc tatgttctat tgatacgaaa
    15061 tgcagggcag acagatgcct cgcaaattga aaaggcggca gttagccaag gaggaaaagc
    15121 agtgaaaaaa acagaaatta gtaaagacgc agacttgcac gaaatttatc tagctggagg
    15181 ttgtttctgg ggagtggagg aatatttctc acgcgttccc ggggtgacgg atgccgtttc
    15241 aggctatgca aatggtagag gagaaacaac caagtacgaa ttgattaacc aaacaggtca
    15301 tgcagaaacc gtccatgtca cctatgatgc caagcaaatt tctctcaagg aaatcctgct
    15361 tcactatttc cgcattatca atccaaccag caaaaataaa caaggaaatg atgtggggac
    15421 ccagtaccgt actggtgttt attacacaga tgacaaggat ttggaagtga ttaaccaagt
    15481 ctttgatgag gtggctaaga aatacgatca acctctagca gttgaaaagg aaaacttgaa
    15541 gaattttgtg gtggctgagg attaccatca agactatctc aagaaaaatc caaatggcta
    15601 ctgccatatc aatgttaatc aggcggccta tcctgtcatt gatgccagca aatatccaaa
    15661 accaagtgat gaggaattga aaaagaccct gtcacctgag gagtatgcag ttacccagga
    15721 aaatcaaaca gaacgagctt tctcaaaccg ttactgggat aaatttgaat ccggtatcta
    15781 tgtggatata gcaactgggg aacctctctt ttcatcaaaa gacaaatttg agtctggttg
    15841 tggctggcct agttttaccc aacccatcag tccagatgtt gtcacctaca aggaagataa
    15901 gtcctacaat atgacgcgta tggaagtgcg gagccgagta ggagattctc accttgggca
    15961 tgtctttacg gatggtccac aggacaaggg cggcttacgt tactgtatca atagcctctc
    16021 tatccgcttt attcccaaag accaaatgga agaaaaaggc tacgcttatt tactagatta
    16081 tgttgattaa tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    16141 agggttactg acttcgtcag ttttatctac aacctcaaag ctatactttg agctgacttc
    16201 gtcagtttta tctacaacct caaagctata ctttgagctg acttcgtcag ttttatttac
    16261 aacctcaaag ctatactttg agaaacctgt ggctatcttc ctagtttact ttttgatttt
    16321 tattgagtat aagaggtctt tcctaagcag ttagaggaga attttgctat actgatacta
    16381 gtaagtgaca aaggagagaa gcatgaccta cacaatctta atcgtagaag atgaatatct
    16441 ggtaagacaa ggtttgacta aactggtcaa tgtagcagcc tacgatatgg aaatcatcga
    16501 tcaggctgaa aatggaaggc aggcttggga attgatccaa aagcaggtgc cagatatcat
    16561 tttaaccgat atcaacatgc ctcatctaaa tggcatccag ttggccagtc tggtacgaga
    16621 aacctatcct caggttcatt tggtcttttt aacaggttac gatgattttg attatgcctt
    16681 gtctgctgtc aaactaggtg tggacgacta cctgctcaaa cccttttctc gtcaggatat
    16741 tgaggaaatg ttggggaaaa tcaaacaaaa actagacaag gaagagaaag aagagcagtt
    16801 acaagattta ttgactaata ggtttgaagg aaacatggcc cagaaaatcc agtctcatct
    16861 ggctgatagc caatttagtt taaagtcttt agccagtgac ttaggtttta gtccgaccta
    16921 tctgagttcc ttgattaaga aagagttggg cttgcctttt caggattatc tggtgagaga
    16981 acgtgttaaa caagccaagc tcttgctttt aactacagat ttgaagattt atgagatcgc
    17041 agagaaggtt ggttttgaag atatgaacta ttttacccaa cgttttaagc agattgcagg
    17101 tgtgacacct cgtcagttta agaagggaga aaaccgatga agcgttcttc tcttttagtt
    17161 agaatggtta tttccatctt tctggtcttt ctcattctcc tagctctggt tggaactttc
    17221 tactatcaat caagttcttc agccattgag gccaccattg agggcaacag ccaaacgacc
    17281 atcagccaga ctagccactt tattcagtct tatatcaaaa aactagaaac cacctcgact
    17341 ggtttgaccc agcagacgga tgttctggcc tatgctgaga atcccagtca agacaaggtc
    17401 gagggaatcc gagatttgtt tttgaccatc ttgaagtcag ataaggactt gaaaactgtt
    17461 gtgctggtga ccaaatctgg tcaggtcatt tctacagatg acagtgtgca gatgaaaact
    17521 tcctctgata tgatggctga ggattggtac caaaaggcta ttcatcaggg agctatgcct
    17581 gttttgactc cagctcgtaa atcagatagt cagtgggtca tttctgtcac tcaagaactt
    17641 gttgatgcaa agggagccaa tcttggtgtg cttcgtttgg atatttctta tgaaactctg
    17701 gaagcctatc tcaatcaact ccagttgggg cagcagggct ttgccttcat tatcaatgaa
    17761 aaccatgaat ttgtctacca tcctcaacac acagtttata gttcgtctag caaaatggag
    17821 gctatgaaac cctacatcga gacaggtcag ggttatactc ctggtcacaa atcctacgtc
    17881 agtcaagaga agattgcagg aactgattgg acggtacttg gcgtgtcatc attggaaaag
    17941 ttagaccagg ttcggagtca gctcttgtgg accttgcttg gggccagtgt cacatctctt
    18001 cttgtctgtc tctgcttagt gtggttcagt cttaaacgct ggattgctcc tttgaaggat
    18061 ttgagagaaa ccatgttgga aattgcttct ggtgctcaaa atcttcgtgc caaggaagtt
    18121 ggtgcctatg aactgagaga agtaactcgc caatttaatg ccatgttgga tcagattgat
    18181 cagttgatgg tagctattcg tagccaggaa gaaacgaccc gtcagtacca acttcaagcc
    18241 ctttcgagcc agattaatcc acatttcctc tataacactt tggacaccat catctggatg
    18301 gctgaatttc atgatagtca gcgagtggtg caggtgacca agtccttggc aacctatttc
    18361 cgcttggcgc tcaatcaagg caaggacttg atttgtctct ctgacgaaat caatcatgtc
    18421 cgccagtatc tctttatcca gaaacaacgc tatggagata agctggaata cgaaattaat
    18481 gaaaatgttg cctttgataa tttagtctta cccaagctgg tcctacaacc ccttgtagaa
    18541 aatgctcttt accatggcat taaggaaaag gaaggtcagg gccatattaa actttctgtc
    18601 cagaaacagg attcgggatt ggtcatccgt attgaggatg atggcgttgg cttccaagat
    18661 gctggtgata gtagtcaaag tcaactcaaa cgtgggggag ttggtcttca aaatgtcgat
    18721 caacggctca aacttcattt tggagccaat taccagatga agattgattc tagaccccaa
    18781 aaaggaacga aagttgaaat atatataaat agaatagaaa ctagctaact cccagtcaat
    18841 tctgggagtt ttatgcgtaa ttgggcaagc tttctaggtt gtctatcttg ctaaaaacaa
    18901 gaaaaaacgg tatgatagaa gagtaacaac agaggtaaca gagatgaacg agacacagat
    18961 tcaaagagaa acacgtcagg tagtggaaga tgttttagaa aagaccaatt tgaagcaggg
    19021 ggtccttttt gttttaggcc tatcttctag tgaggtgcta ggtggtcaga ttgggaaaga
    19081 atccagtcaa gagattggtg agctgatagt ggagactatc ttgggtattc taggtagtag
    19141 aggtatccat ttagcagttc aaggttgtga gcatgtcaat cgggctctcg ttgttgaacg
    19201 tcaggtggca gagcagtttg atctggaaat tgtcagtgtc catcctactc ttcatgcagg
    19261 aggttcgggg cagttggcag cctttaagtt tatgcaggat ccagttgagg ttgaatttat
    19321 caaggctcat gctggattgg atatcggaga cactgcaatt ggcatgcatg tcaagcatgt
    19381 tcaggttccg attcgcccta ttttgagaga gattggtcat gcccatgtaa cggcactggc
    19441 tagtcgtcca aaattaatcg gaggtgcgcg tgcgcactat ccgcaagatg ctattagaaa
    19501 gtcttgagaa tgaataaagg agatgaaagt gtttaaaaaa gaccgttttt caattcgtaa
    19561 gattaaggga gttgtaggct ctgtatttct tggaagcctt ttgatggctc cttctgtagt
    19621 ggacgcagct acctatcact atgtaaataa agagattatt tcacaagaag ctaaagattt
    19681 aattcagaca ggaaagcctg acaggaatga agttgtatat ggtttggtgt atcaaaaaga
    19741 tcagttgcct caaacaggga cagaagcatc tgttttgaca gcttttggtt tgctgactgt
    19801 tgggagcttg cttttaatct acaagagaaa gaaaattgct agcgtctttc tagttggagc
    19861 tatgggattg gtagttcttc ctagtgcagg ggctgtagac ccagttgcga ccctagcgct
    19921 ggctagtcga gagggtgttg ttgaaatgga tggctatcgc tatgttggtt atctatcagg
    19981 tgacatcctc aaaacgcttg gcttggacac tgttttagaa gaaacctcag caaaacctgg
    20041 agaggtgact gtagtcgaag ttgagactcc tcaatcaaca acaaatcagg agcaagctag
    20101 gacagaaaac caagtagtag agacagagga agctccaaaa gaagaagcac ctagaacaga
    20161 agaaagtcca aaggaagaac caaaatcgga ggtaaaacct actgacgaca cccttcctaa
    20221 agtagaagag gggaaagaag attcagcaga accagctcca gttgaagaag taggtggaga
    20281 agttgagtca aaaccagagg aaaaagtagc agttaagcca gaaagtcaac catcagacaa
    20341 accagctgag gaatcaaaag ttgaaccacc agtagaacaa gcaaaagtcc cagaacaacc
    20401 cgtgcaacct acacaagctg agcaaccaag tacaccaaaa gaatcatcac aacaagaaaa
    20461 tcctaaagaa gataggggag cggaagagac accgaaacaa gaagatgaac agccagcaga
    20521 agccccagaa atcaaggttg aagaaccagt agaatcaaaa gaggagacta aaacagctaa
    20581 ggggacgcaa gaagaaggca aagaaggtca agcaccagta caagaagtaa acccagaata
    20641 taaagtaaca acaggtacag ttgagaagtc taccgaaagt gaattagatt tcacaacaga
    20701 agtagttccg gatgacacaa aatatgtaga tgaagaagtt gttgaacgtc aagggtctaa
    20761 aggagttcaa gttacgaaaa caacttacga aacagtggaa gttgtagaga cagacaaagt
    20821 cctttctaca actacagaag tgaaaactcc tgttgttcct aaagtcgtta aaaaaggaac
    20881 aaaaccagtt gaaggaacag cagttgaaac aagagaagaa gtcattcctt ttgctacaaa
    20941 agaacaagaa gatggcactt taaaacgcgg aacaagacaa gtagctcaag aaggtgtaaa
    21001 cggtaagaaa caaattactg aaacctataa aacaattcgc ggagaaaaaa caaacgaagc
    21061 tccaacagta gaagaaacag ttctccaagc acctcaagat gagattatca aaaaaggcac
    21121 aaaaggttta gaaaaaccaa ccttagaatg ggttaaaaca gataaagatg tcttgaagaa
    21181 gagtgcgaca gccagttata cattgaataa accagatggg gtagaaatca aatccatcaa
    21241 agtagctcta aaagataata ctggaacagt tattaaagaa gtaacggtag aagaaaataa
    21301 cttaaacgtt actttagaca acttgaaata ttatcaaggt tatacactat ccacaaccat
    21361 ggtctataat cgaggcgaag gcgaagaaac tgaaacgtta gaagataaag aagttcagtt
    21421 agaccttaaa aaagttgaaa tcaaaaacat caaagaaact agcttgatga gtgtggatga
    21481 tgctggtgtt gaaacagata agagcttact tactgaaaaa ccgacagacg ttgctccact
    21541 ttacctacga gtgacaactc atgataacaa agtaacaaga cttgctgttg ataagattga
    21601 agaagtagaa gaagacggaa aaactttata caaagttact gccaaagcac cagacttagt
    21661 tcaacgtaat gctgataaca cacttagcga agagtatgtt cattactttg aaaaacaact
    21721 tccaaaaatt ggaaatgtgt attacaactt caacgagttg attacagata tgcaaaaaac
    21781 accgaatggc gagtttaaac ttggtgcaga cttgaatgct gtcaatgttc caacaccaaa
    21841 taaatcttat gtgactgcta aatttactgg taagttgtat agtgaaggtg ataaacacta
    21901 tactattcac aacttagcac gtccattgtt tgcgcaagct gaaaacgctc atattcatga
    21961 catcaacctc ggtaatgtaa atattaatat gccgtgggcg aacaaaacag cacctcttgg
    22021 tgaaatgttc aagaagtcaa ctattgaaaa cgtcaaagta acaggtaatg ttgtcggtaa
    22081 caatgacgtt acaggtatgg tcaacaaact ggacgaatct gatatgcgta acgtagcttt
    22141 cattggaaat attacaagtg taggtagcgc tggatggtgg tctggtggac ttgtcagtga
    22201 aagctggaga agtaacacag ataattctta tattgatacc accatcaaag gtaataaagc
    22261 taaggtaggt ggattaattg ctaagttaaa tcacggtgct gacccacgag atgttggtgc
    22321 gagaggtcgt ttgaagaact ctgtcgcaaa aggtactatt gatgtgagag acccacaaga
    22381 aactggtgga ttgctgcatt ctaactggtc atggggtctt gcagaaaaca atattaccat
    22441 gatgaaagtg aagaatggag gagaaatttt atatggttct cgtgatgcag aagatgatga
    22501 ttacttcgga gcgaattggg tgcgtaataa taatgcgttc gtcaatggaa tcagtgaagg
    22561 gaaacaatcc tattctcgtt ctagtcgctg gaaagggatt tctgaagatg aagctaaaac
    22621 tcgtattgcc aaaatgggaa ttacagctca tgaatacgaa attacacaac atttgactga
    22681 taaattgaac cgtgcagcat ttaaagaaga cacatataaa acaactcaag attacaaaac
    22741 tgaaagagaa ttagcgtatc gtaatattga aaagcttcaa ccattctaca ataaagaatg
    22801 gattatcaac caaggtaaca aattaacaga cggttcaaac ttaatgatta aagaggtatt
    22861 gtccgttata ggtatgaaga acggtcagtt cgtgaccgat ttgtctgata ttgataagat
    22921 tatgattcac tacgctgatg gtacgaaaga agaaaaaact gtcacacgta aagctgactc
    22981 aaaagtgcaa caaattcgtg aatatagtgt tgaaggtctt ggtgatgttg tgtacacacc
    23041 aaatatggtc gaaaaagata gagcgcaatt aattactgat attaaggcga aattggatag
    23101 cgtccaattg atttcaccag aagtgcgcaa tttgatggat aaacgtggca aagcgcatga
    23161 aaacacggat gaacgtcgta atggctacat tcgaaaccta ttccttgaag aaagtttgga
    23221 tgaagtgaaa ggaaaccttg ataagcttgt gaaagctctt gttgaaaatg aagaccatca
    23281 attgaatggt gatgaagcgg caatgaaagc tcttgtcaag aaagttgaag acaacaaagc
    23341 gaaaatcatg ttaggtcttg cttatctcaa tcgctactat ggattcaaat atgacgaaaa
    23401 gtctatgaag gatattatga tgttcaaacc ggacttctat ggtaagaatg ttagtgtctt
    23461 ggacttcttg attagagttg gttcaagaga acacaatatt aaaggtaaca gaacgttaga
    23521 agcttatcgt gaagtaattg gtggaacgat tggtatcggt gagttaaacg gtttcttaaa
    23581 ctataatatg cgtttattca cagaagaaac tgacatcaat acttggtaca aaaaagctgt
    23641 atcgcatacc aactatattg ttgaaaaaca atcctcaaac cctgcgtttg ccaacaagaa
    23701 atatcgcctt tatgaaaact tgaacaatgg tgaacatggt aaatatattt taccacttct
    23761 cactacgaag aaagctcata tgttcttgat ttcaacctat aatacattag cgtttagtgc
    23821 gtttgagaaa tatggtaaga atacagaagc tgaacgtgaa gcgtttaaga aagaaatcga
    23881 tttacgtgct caagagcaaa ttaattactt agacttctgg tcaagacttg cagctgataa
    23941 tgtacgtgac agattgttaa aatctgaaaa tatggttccg tctgcaattt gggataacca
    24001 agaagttcca ggtcatggat gggctgatag aatgggtcat aataagaatg gtgactatgc
    24061 tccggttcgt gagttctatg gacctacagg taaatggcat ggatacaatg gtacgggtgc
    24121 atatgcttat atctttacta atccacaaaa ctcagaagct gtatattata tcatatctag
    24181 tctgatcagt gatttcggta cttctgcatt cactcatgaa actacacaca ttaatgaccg
    24241 tatggcgtat ctaggtggat ggcgtcaccg tgaaggtact gacgtagaag catttgccca
    24301 aggtatgtta caatcaccgg ctgtctcaag tccgaacggc gactacggtg ctttaggtct
    24361 taacatggct tacaaacgtg aaaacgatgg taaccaatgg tacaactatg attcaaataa
    24421 attagatagt cgtgcgaaga ttgaccatta catgaagaat tacaacgaag cgctcatgat
    24481 gcttgaccac ttagaagctg atgccgttat cgcgaagaat aacggagata acaacaagtg
    24541 gttcaagaag atggataaga aatggcgtga gaacgctaat cgaaatggat tagtgggaca
    24601 accacaccaa tgggatttac ttcgtgacct aaatgaagaa gagaataaga agaaattgac
    24661 aagcattgat gaccttgtag atggaaatta tgtaacgaag cataatatgc cgggtaataa
    24721 acactatcgt gctgaagggt ttgatacagc gtatcaaact gtaaacatga tggctggtat
    24781 ttacggtggt aatactagta agagtgctgt tggttctatc tcgttcaaac ataacacctt
    24841 ccgtatgtgg ggttacttcg gttatcttga tggatttgta ggttatgcat ctaacaaata
    24901 taaagacgcg gctaacaaag aaaataaagg cttacttggc gacgacttta ttatcaagaa
    24961 agtgtctgac ggtaaatttg acagcctaga agcttggaag aaagaatggt ttaaagaagt
    25021 taaagctaaa ggtgaaaaag gatttgttgc tattgaaatt gatggtaaaa caatcactaa
    25081 ctatgctgaa cttcgtgaat tgttcgacaa agctgttgaa gctgacctga aagctggtaa
    25141 ctctaaccaa acagttgccc ttaaagaaaa ggtttataaa caactcttgc agaaatcaga
    25201 tggatttgta ggaaatcttt ttaaagcata gattgtatta aatagatgag taaaaaaggt
    25261 agattaagtt tttcttgatc tgccttttta tgctatactt aaggtatgca tagaaaaaca
    25321 gtgattgatt ttaggacttt gggggagaga tataccttta cccagcctat taaagagttg
    25381 aaaacgagaa atgtagaaga agtggcagat ttgctggcac aagtggaaag ctaccaagag
    25441 caaggttatt atgtggtggg gtatgtcagc tacgaggctg cacctgcttt tgaggagaaa
    25501 ttagcagttc acaaggttcc tctactgggc gagtacttgc tttactttac tgttcacgat
    25561 agggtagaga cctcccctat tcctctgact tatgaggata ttgatttgcc ctcaaattgg
    25621 caggaagtga cgtctgcagc agactatgaa aaggccattg cccagataca ccatcacttg
    25681 aggcagggag acacctatca ggtcaactac accgtccaac tcaagcaaaa gttaagtgcc
    25741 aatccttttg ccatctacaa tcgtatggtg gtagagcagg aggcgggcta caatgcctat
    25801 gtggaacatg acgagatggc agtgatttcc atgagcccag agctcttttt tgagcaaaat
    25861 gatcgcgagt tgacaacacg accaatgaag gggacgactc agcgtggggt aactgaccaa
    25921 gaagatcttg aacaggccag ttggttggaa caggatccca aaaatcgctc tgaaaatatg
    25981 atgattgtgg acctcttgcg caatgatatg aaccgtattt ctgaagttgg gagcgagcac
    26041 gtggagcgtc tgtgtcaggt agagcagtat tcaactgttt ggcagatgac ttcgaccatc
    26101 aagagtcagt tgcgagagga tgtggacctt gttgaaatct tccgctcact ctttccttgt
    26161 ggttccataa cgggtgcacc gaaaattgcg acaatggaga ttatcaagga cttggagcct
    26221 caaccgcgtg gagtctactg tggaacgatt ggtctcttgc ttccaaatgg acgacggatt
    26281 tttaatgtgg ctattcgtac cattcaactt cacaaaggtc aagccattta tggagttggc
    26341 ggagggatta cttgggatag cacatgggaa tctgaatacc gagaggttca tcaaaaggca
    26401 gcagttcttt atcgtaaaca agctcgcttc caactgatta cgacagggga aatcagccag
    26461 aagaacctgc tgtttgaaga tcaacatctg gaaagactga gaaaagctag tcgttatttt
    26521 gcttttcctt ttgatgcaga agacttggga cacaagattg aggaagagtg tcaggattgt
    26581 gaagctaatc gagattaccg cttgcgaatc agccttagca aatctggaga gatagaagtc
    26641 aatcgtcaag tattaacccc tctcagtaca agcttttgtc aggcccaagt ctgtcttcag
    26701 gaagctgctt tgaatcaatc ctttacctac tttaaaacca ctcaccgacc gcatttgagc
    26761 ctaggagaac aagagaagat ttaccacaat aagtcaggag aactgcttga aacctctata
    26821 ggaaatttgg ttctgaaaat cgctggaaaa ctctacacac cgcctatccg acttggaatc
    26881 ttgccaggaa tttaccgtca gcatttgcta gaaacaggac aggtagaaga gaaagtcttg
    26941 accttggcag atttaaccca agcagaagct atttacggct gtaatgcagt gagaggcttg
    27001 tatgaactaa gccttgagga gaactagatg aaattgatat ttttgcatgg gttagggcag
    27061 tcagcagagt cttggaaaga agttcggaat ctactgacag attatccttc tgaggctatc
    27121 gagttatttc cttctggagt tagtaactat caacaagcta aagagcgagt ttatcagcac
    27181 ctagctcaag agacagaacc ttttgttttg attggattgt ccttaggtgc tgccctgaca
    27241 ctagaacttt ccagttacga tttaccaaat cttcgagctt tgattctgtc aggatgcccg
    27301 cttaaattag cagggaatat cctattttat cttcaattgc tgatttttaa actacttccc
    27361 aaaagagtat ttgaaaaaca gggagcagac aagactctta tggtcggagt ttctgaggaa
    27421 ttgaagacac ttgatttaac ggatatagca gggacttgct cctatccaac cttactaatt
    27481 tgtggcagca aagataaacc gaatcttagt tctatgaaag ctctccatag actgttaaca
    27541 gattcgcagt ttcagatcat tcctgatggc cctcatgtct tgaataaggc aaaaccaaag
    27601 gagtttgtag aaaagaccag aagtttcctt gaattgctga aataagtttg ataaaataat
    27661 attgaaatcg atatcataat tatgggagaa agaaatgaat aaacgtctat ttttaaaaat
    27721 gagtctggtg acgttgccaa ttttagcctt gttttcacaa ccagttttgg cggaagaaaa
    27781 catccatttt tcgagctgta aggaagcttg ggcgaatggc tattcggata ttcacgaggg
    27841 ggaacctggt tattctgcca agttagaccg tgatcatgat ggtgtggctt gcgaattgaa
    27901 aaatgctcct aagggtgctt ttaaagcaaa acagtcaacg gctattcaaa tcaacacaag
    27961 ttcagcaaca acaagtggtt gggttaagca ggacggcgct tggtactact ttgatggaaa
    28021 tggaaatcta gtgaaaaatg catggcaggg aagctattac ctgaaagctg atggtaaaat
    28081 ggcacagagt gaatggattt atgactcttc ttatcaagct tggtattatt tgaaatcaga
    28141 tggttcttat gcaaaaaatg catggcaagg agcttattac cttaaatcaa acggtaaaat
    28201 ggcacaaggt gagtgggttt atgattcttc ttaccaagca tggtattact tgaaatcaga
    28261 tggttcatat gctcgcaatg catggcaagg aaactactat ttgaaatcag atggtaaaat
    28321 ggctaaaggt gaatgggttt atgatgccac ctatcaagct tggtattatt tgacatcaga
    28381 tggttcttat gcttacagta catggcaagg aaattactat ctaaaatcgg atggtaaaat
    28441 ggctgtcaat gaatgggttg atggtggacg ttattatgtt ggcgctgacg gagtttggaa
    28501 ggaaggtcaa gcaagtacag cttcttctag taatgatagc aatagtgaat attctgctgc
    28561 tttaggaaag gcaaaaagtt ataattcgtt attccacatg tcaaaaaaaa cgtatgtata
    28621 gacaattaac ttctgatttt gataaatttt caaatgatgc agctcaatat gccattgatc
    28681 attagatgat taacagatac tggtaggcga aaaaattcct tataattcac ttacgcaaac
    28741 ctttgcataa gtgaatggat tttgatatac tagtactgta agcattttca attactacac
    28801 aatgaaaaag gagaatatga tgagtcaaaa gattattggg attgaccttg gtggaacttc
    28861 tatcaaattt gcaatcttaa caacagcagg agaaatccaa ggaaaatggt caatcaagac
    28921 caacattttg gatgagggaa gtcatatcgt tgatgatatg attgagtcta ttcaacatcg
    28981 tttggacttg cttggattgg cagcagcgga cttccaaggc attggaatgg gatcaccagg
    29041 tgtggttgac cgtgacaaag ggactgttat cggtgcctac aacttgaact ggaaaaccct
    29101 tcaaccaatc aaacaaaaga ttgaaaaagc cttgggcatt ccatttttca tcgataatga
    29161 tgccaacgta gcagctcttg gtgagcgctg gatgggtgct ggagataacc aaccagacgt
    29221 tgtctttatg acactcggta ctggtgttgg tggtggtatt gtcgcagaag gcaaattgct
    29281 tcatggtgtt gctggtgcag caggtgaact tggtcatatc actgttgatt ttgaccaacc
    29341 aattgcatgt acttgtggta aaaaaggctg ccttgagaca gttgcttcag caacaggaat
    29401 tgtcaacttg actcgtcgct atgccgatga atacgaaggc gatgcagcct tgaaacgctt
    29461 gattgataac ggagaagaag taactgctaa gactgtcttt gatctcgcaa aagaaggaga
    29521 cgaccttgct ttgattgttt accgtaactt ctcacgttac ttgggaatcg cttgtgctaa
    29581 cattggttca atcctaaacc catcaacaat cgtcatcggt ggtggtgtgt cagctgcggg
    29641 agaattcctt ctacaaggtg ttcaaaaagt ctatgatgaa aatactttcc cacaagtacg
    29701 cacatctact aaattagctc ttgcaactct aggaaatgac gctggagtta tcggagcagc
    29761 atcacttgta ttgcaataag ataatgagag aggaaaaatg ctaacctaga gttagtaatg
    29821 ttcctctttt attttttatg ctatactagt taggacaatg aatgaggtga gagtaaatga
    29881 caaaagcaga tacgattttt aaagagaata ttgaacgcat tctaaaggaa ggtgttttct
    29941 cagagcaggc tcgtcctaag tacaaggatg ggactgttgc taattccaag tatgtaactg
    30001 gtgccttttc cgagtacgac ttatctaaag gagaatttcc tatcacaacc ttgcgtccca
    30061 ttgcaatcaa atccgccatc aaagaagttc tctggattta ccaagaccag tcaaatagct
    30121 tagaagtgct taatgacaag tacaatgttc actactggaa tgactgggaa gttggagaca
    30181 cgggaaccat tggtgagcgc tatggtgccg ttgttaagaa acacgacatt atcaataagc
    30241 ttctcaaaca gttggaaacc aatccttgga atcgccgcaa tattatttcg ctctgggatt
    30301 accaagcttt cgaagaaaca gatgggctgc tcccgtgcgc ctttcagacc atgtttgatg
    30361 tccggcgtgt tgatggggaa atctatctgg atgcgacctt gacccagcgc tccaatgata
    30421 tgctggtggc ccaccacatc aacgctatgc agtatgtggc tttacagatg atgattgcca
    30481 aacattttgg ttggaaggtt gggaagttct tctatttcat caacaacctc catatctatg
    30541 ataatcaatt tgaacaagct caggaattgc tccgtcggga gccgtcaaac tgccaaccac
    30601 gcttggtttt aaatgttcct gatgggacta atttctttga tatcaaagca gaagattttg
    30661 agttggtgga ttatgaccct gttaagccac agttgaagtt tgacctagct atttaaaaga
    30721 atagaaaaaa gaagttgaga ataatcccaa cttcttttgt ttcttaacgt gatacgcggc
    30781 gacgagctgc ttttttacga ttttcttcga tgaaagctgc tttttgctct tctggttcga
    30841 ttactttctt tttaaatgcg tatactgcac ctgcaacggc agcgacagtt cctgcgacac
    30901 ctgttacaag acctttagcg aatcctttag ccatgagtct tcctccttta tattctcaat
    30961 cagccagcct cctcaagagg tcacattttt ctgactgacc tttttgtgtt ataataatag
    31021 taacgaaaaa atgggaattt ttcaaggaaa aaagatgaaa acaaaaataa ttgtgattgt
    31081 tggaccgact gctgttggaa agacggctct agctattgaa gttgcaaagc gctttaatgg
    31141 cgaagtggtt agtggagata gccagcaagt ctatcgagga cttgatattg ggacggccaa
    31201 ggctagtcca gaagagcagg cagctgttcc tcatcattta atcgatgtta gagagataac
    31261 cgagtcttac tcggcttttg attttgtttc agaagctaag atgactattg aggatattca
    31321 gagccgtggc aagctagcca ttatcgccgg tgggactgga ctttatatcc agagcttgct
    31381 agaaggttac cacctaggtg gggagactcc ttatgaggag attttagctt atcgagctag
    31441 tttggagcca tattcagatg aggaattagc ccatttggtg gagcaagcag gccttgagat
    31501 tccccagttt aatcgtcgtc gtgctatgcg tgccttagaa attgcccatt ttggtcagga
    31561 tttggaaaat caagagatct tgtatgaacc gctgattatc tgcttggatg atgaacgtag
    31621 tcaactttat gagcgtatca accaccgagt ggatttgatg tttgaggctg ggcttttgga
    31681 tgaggccaag tggctgtttg accattcccc taatgtacag gctgctaaag gaattggcta
    31741 taaggaactc tttccttatt tccgtggaga gcagaccttt gaggaagctc gtgagagtct
    31801 taaacaggcg acccgtcgtt ttgccaagcg tcagctgacc tggttccgta atcgcatgca
    31861 ggtcaccttt tatcagattg gagaatctgg tgtacaagac cgcattttaa gccagataga
    31921 ggagttttta gatgattgaa acggagaaaa aagaggagcg agtcctgctg attggtgtgg
    31981 aattgcaggg tatggacagt tttgacctct ccatggaaga attggctagt ttagcgaaaa
    32041 cggcaggggc agtcgttgta gatagctaca gacaaaaacg tgaaaaatat gattccaaga
    32101 ccttcgtcgg ctctggtaag ttggaagaga ttgcgcttat ggtggatgca gaagaaatca
    32161 ctactgtcat cgtcaacaac cgtctgaccc caaggcagaa tgtcaatcta gaggaagttc
    32221 tcggtgttaa ggtcattgac cgtatgcagt tgattttgga tatctttgcc atgcgggctc
    32281 gaagccatga agggaagctc caagtccacc tagcccaact caaatacctc ttgcctcgct
    32341 tggttggtca ggggattatg ctcagccgtc aggcaggggg aattggttcc cgtggtcctg
    32401 gtgaaagcca gctggagctg aaccgtcgta gcgttcgcaa tcaaatcacg gatatcgagc
    32461 gccagctcaa ggtggttgag aaaaatcggg cgactgtcag agaaaaacgt ttggagtcta
    32521 gcacctttaa gattggtttg attggttata ccaatgctgg gaaatcaact atcatgaaca
    32581 tcttgaccag taagacccag tatgaagcag atgagctctt tgcgactctg gatgcgacaa
    32641 ccaagagtat tcatctggga ggcaatctcc aagtaacttt gacagatacc gttggcttta
    32701 ttcaagattt gccgacagag ttggtgtcca gtttcaagtc aaccttggaa gaaagcaagc
    32761 atgtggacct tctggttcat gttatcgatg ctagcaatcc ttaccacgag gagcatgaaa
    32821 aaacggttct ctccatcatg aaagacctgg acatggaaga tattcctcac ttgacgcttt
    32881 ataataaagc ggatttggtg gaggatttca cgcctaccca aacgccatat accctcattt
    32941 ctgccaagtc tgaggacagt cgtgaaaact tgcaagcatt attgctagat aagattaagg
    33001 aaatttttga agcatttacc ctgcgagtgc ctttttcaaa gtcctacaag attcatgatt
    33061 tagagagtgt tgcaattctg gaagaacgtg attatcagga agacggcgaa gtgattacag
    33121 gctacatttc cgagaaaaat aaatggaggt tagaagaatt ttatgactga tattaaaact
    33181 ttggctctaa agtatggagg ttatacaagt ctggacaagg tctatctgga tcagcttcta
    33241 gctggtaaaa cagagcagga gcagttaaca cttattacac ctccgccaag tgttgttaat
    33301 gcctactttg cagaactcta tcagaaaaaa agtcctcagg ctgcgacgga ttattttgca
    33361 gaactcagtc aggaactgaa tctttacaat actgagccaa gtttcaccct agaaaataag
    33421 ccttttattc ggcttaatct gtctggtaaa tcctttggtt tttgttatga gagtgacggc
    33481 tttggtcgga ttttctctga aaatgaggag aaaatctcgg atgacttgct ctttgaaatt
    33541 gcgcaaattt tctcccatca attagtcttt gaagagtctg gtaagattta catgaagcct
    33601 gtcaaggacg aggaagttgt cagcctagaa agtctcacag ctttgactga tttggaaaga
    33661 ttggctgatg gtcgaaaacg tctcaaaggc tacagccaag aggatttatt gcaagaagct
    33721 gctgcttttt ctggcaaacg ctatttccga tcggaaaacc gcacagccat gttatatatt
    33781 gattaattag aaagtatcga atggatattc aatttttagg aacgggggct ggtcagccct
    33841 ctaaagcccg caacgtttca agtctcgccc tgaaactttt ggacgagatt aacgaagttt
    33901 ggctctttga ctgtggagaa ggtacgcaaa atcgcattct ggaaaccaca attcgaccac
    33961 gtaaggtcag caaaatcttt attacccatc tgcatggaga ccacattttt ggtttgccag
    34021 gtttcctttc tagccgtgcc tttcaggcca atgaagagca gacagatttg gaaatctacg
    34081 gacctcaagg aatcaagtca tttgtcttaa ccagccttcg tgtgtcaggt tctcgtctgc
    34141 cctaccgcat tcatttccat gagtttgacc aagattctct gggtaaaatt cttgaaaccg
    34201 ataaattcac tgtgtatgca gaggagctgg accacactat tttctgtgtt ggctatcgtg
    34261 tcatgcaaaa ggatctagaa gggacgctgg atgctgaaaa actcaaggct gctggtgttc
    34321 cgttcggccc gctttttggt aaaatcaaaa acggccagga tcttgttttg gaagacggaa
    34381 ctgaaatcaa ggcagcagac tatatctcag cgccacgtcc aggtaagatt atcactattt
    34441 taggagacac tcgaaaaacg gatgccagtg tgcgtctggc tgtcaatgca gatgtcctag
    34501 ttcatgagtc cacttatggc aagggtgatg aaaaaattgc tcgtaaccat ggtcactcaa
    34561 ctaatatgca agctgcacaa gtagcggtag aagcaggtgc caaacgcctc ctactcaacc
    34621 atatcagtgc ccgtttcctc tcaaaagata taagcaaact caagaaggac gctgccacaa
    34681 tttttgaaaa tgtccatgtg gtcaaagact tggaagaagt ggaaatctag cagtcacaga
    34741 aaggataagt atgcctacta ttctcattac cggagctagc ggtggtctag ctcaagaaat
    34801 ggtcaaactc ctgcccaatg accaactcat cttgcttggt agaaataagg aaaaattagc
    34861 ccaactctac ggaaattatt cccatgcaga attgattgaa attgatatta ccgacgattc
    34921 agccctagaa gctctggtaa ctgatcttta tctccgctat ggcaagattg atgtcttgat
    34981 taacaacgct ggttacggga tttttgaggg atttgaccag attgctgata aagatattca
    35041 ccagatgttt gaggtcaata cctttgccct gatgaatctg tctcgtcacc ttgcggctcg
    35101 tatgaaggaa agcagcaaag ggcatatcat caacatcgtc agcatggcag gtctaatagc
    35161 tactggcaag tctagtcttt actcagcgac caagtttgcg gctattggtt tttcaaatgc
    35221 tctgcgactc gaacttatgc cctatggagt ctatgtgaca acagtcaatc caggtccaat
    35281 ccgaacagga ttttttgacc aagctgaccc agatggaact tatcttaaat cggttgaccg
    35341 cttcctctta gaggcagatg cagtggctaa aaagattgtc aagattatag gcaaaaataa
    35401 acgagaactc aatctcccga ttttgttgaa cctagcccat aagttttata ctctctttcc
    35461 caagctagct gataagttgg caggggaaac ttttaattat aagtaaaaag aaccaatgtg
    35521 caggttgttg ctagcctaca tattggttct tatcatttct caactatcaa actgaacttc
    35581 ttctagtaga tagtcgataa agcgttcgcc catcttagat aggctggttt tctcatgctg
    35641 gatatagacc agctcaatcg ggtcatcaat atccagtggg atagaaacga tattgtctcc
    35701 gtttaggttg ctgttcaaaa tccctgtcgc aatggtataa ccatccaaac caatcaagag
    35761 attaaagagg gtggcacggt cactgaccac aatggatttc ttgtggtgtt cctgagaaag
    35821 aatctcttct gaaaagtaga aggagttgtg cgtcccttgg tcatagctga ggtaagggaa
    35881 attctccaaa tcagacagtt tcaccttgtc tttctttgcc agagggttgg tcttgctgac
    35941 aaagatatgc ggttgcgctg tgaagagatg gtgggctagc aggtgattgt catccagcat
    36001 cttggttaaa acatcacggt tgtaactgtt taagaagagg accccgacct cactgcggaa
    36061 gttcttgacg tcgtcgataa tctcccaagt ccgagtttca cgaaggaaga gttcgtattt
    36121 ctccatatcg cttttcttga gcaaagagac aaaggcattg accacaaagg catagtgttg
    36181 agacgaaacg ctaaagagtt cgcggtgggc gacaggattt ttatagcgtt cctccagaag
    36241 ctgggtctgc tcgacaacct gacgggcata agagagaaac tccatcccat cacgggtcaa
    36301 ggtgattccc ttgggattgc ggataaagat ctcaatgccc atttcatttt ccaaatctcg
    36361 cactgcattg gagagacttg gctgagtgat aaagagttgc ttggctgcct cattcatgga
    36421 gccagtttcg acgattttga taatataatg taattgttga attctcatgt ttttattgta
    36481 ccatacttgc cttagaatcg ctaaagaaga taggaaaata aggagcattg tatgagtctc
    36541 ttcttgaaaa aaacacaaaa ttttgctaga atgagtctta tgaaaacatt ctatgatgtg
    36601 cagcaattcc tcaaacgatt tggtattatt gtttacatgg gaaaacgctt atatgatatt
    36661 gaactgatga agttggaact atctcggatt tacgatgcag ggttgatgga taaattagac
    36721 tatctagagg cagaagcagt tcttcgcaga gagcacaagg tagaattgga ttatattgag
    36781 aaaaatggag aaaagaacta atggttactt ggattttgtg ggcacttata ctagcaatgt
    36841 tggcgtggat gggctttaac tatcttcgta ttcgccgtgc ggctaaaatt gtggacaatg
    36901 aggagtttga agccttgatt cgtacgggtc aattgattga tttgcgcgac ccagcagaat
    36961 tccacagaaa acatatcctt ggtgcacgca atattccttc aagtcagttg aaaactagtc
    37021 ttgcagccct tcgtaaagat aaacctgtcc ttctctacga aaaccaacgt gcgcaacgag
    37081 ttacaaatgc agctctttac ttgaaaaaac aaggtttttc tgagatttat atcctttctt
    37141 atggcttgga ttcttggaaa gggaaagtga agactagcta accttatttc caaattagtt
    37201 gaatgatagg atgaagctat tgttttatag tataattaat ttgtataaaa tttaaggagt
    37261 tcttagaaca tgaaagaaaa gaagaaaatc cactttttgt gggtatcttg tcgattattc
    37321 ttggtttgtt atttccaatt gtaggcctga ttttgggtat cataggattg gtcttggcta
    37381 tttcatacca aaaagagtca caattagact ataaaataga aaagattctt aatatcttag
    37441 gaattgtgat ttctgtagtt aactggattg tagcaatcgc cttaattttt cggtaaataa
    37501 aagaaaaaag ctttagtttt aaagcttttt ttattttatc gactcatctc taaatagttt
    37561 ttaatgattt gtaactcttt ttggttcaaa gggcggtagt taccttctgc taaatctggg
    37621 ttcaatgtga agtccccaaa ttggattctc ttgaggctag tcaccttaac accaaccgag
    37681 aggaacattt tcttgatttg atgaaatttt ccttctgaaa tggtgataga ggcttgactg
    37741 atggagggac ttgcagatag aatctctagt tttgcgggtt tacagacagt accatctaaa
    37801 aagacaattc ccttttgaaa ggcttggata tggtcaggtg ttagaagtcc attaacctca
    37861 acttgataag tcttatcgac atgatattgg ggatggagga gttggaagcc caagggaccg
    37921 ttatcggtca agagaaggag tcctgttgta tctcggtcca gtcggccgac ggcatagagc
    37981 ttgtcagact ggatgtcaga tggaagcaag tccatgacgg tcggaagttc cttgtctttg
    38041 ttggctgtaa cgacaccagc aggtttatga agcataagat aggtgtgttc atagccttga
    38101 atgattcgat cctgaaaaag gagttcttgt agtcctgtat cgatattttg agctagggag
    38161 cgggctgggc aaccatcgac tagaatgtcc cctttgagta aggcttgttt catggccttt
    38221 cggctgattt tttcttgagc taataaatta tctaaacgca tactgtgcct atcttatcat
    38281 aagtcgcttg ctttgaaaag gcttgacgtg aaaagaaaag tggagtgaaa acatttacac
    38341 ttgcttgagt tatgttattt acttgaaatt atggtataat cgttcagtta gaaaataaat
    38401 tttgaatatt atagaggaaa tcatgacaaa attaagagaa gatatccgta acattgcgat
    38461 tatcgcccac gttgaccacg gtaaaacaac cctggttgac gaattattga aacaatcaga
    38521 aacgcttgat gcacgtactg aattggcaga gcgtgctatg gactcaaacg atatcgaaaa
    38581 agagcgtgga attaccatcc ttgctaaaaa tactgccgtt gcttacaacg gaactcgtat
    38641 caacattatg gacacaccag gacacgcgga cttcggtgga gaagttgagc gtatcatgaa
    38701 aatggttgac ggtgttgtct tggtcgtaga tgcctatgaa ggaaccatgc cacaaactcg
    38761 tttcgtattg aaaaaagcct tggaacaaga ccttgtccca atcgtggttg ttaacaaaat
    38821 cgataagcca tcagctcgtc cagcagaagt agtggatgaa gtcttggaac ttttcatcga
    38881 gcttggtgca gatgacgacc agcttgattt cccagtggtt tatgcttcag cgatcaacgg
    38941 aacttcttca ttgtcagatg atccagctga ccaagaagcg actatggcac caatctttga
    39001 cacgattatc gaccatatcc cagctccagt agataactca gatgagcctt tgcagttcca
    39061 agtgtcactt ttggactaca atgacttcgt tggacgtatc ggtatcggtc gtgtcttccg
    39121 tggtacagtt aaggttgggg accaagttac cctttctaaa cttgacggta caactaaaaa
    39181 cttccgtgtt acaaaactct tcggtttctt tggtttggaa cgtcgtgaaa tccaagaagc
    39241 caaagcgggt gacttgattg ccgtttcagg tatggaagac atctttgtcg gtgaaaccat
    39301 cactccgaca gatgcagtag aagctcttcc aatcctacac atcgatgagc caactcttca
    39361 aatgactttc ttggtcaaca actcaccatt tgctggtaaa gaaggtaaat gggtaacttc
    39421 tcgtaaggtg gaagaacgct tgcaggcaga attgcaaaca gacgtttccc ttcgtgttga
    39481 cccaactgat tcaccagata aatggactgt ttcaggacgt ggagaattgc acttgtcaat
    39541 ccttatcgaa acaatgcgtc gtgagggcta tgaacttcaa gtatctcgtc cagaagttat
    39601 cgtaaaagaa atcgacggtg ttaaatgtga accatttgaa cgtgtacaaa tcgacactcc
    39661 agaagaatac caagggtctg ttatccaaag cctttctgaa cgtaaaggtg aaatgttgga
    39721 tatgatttca actggtaatg gtcaaactcg tttggtcttc cttgttccag cgcgtggttt
    39781 gattggatac tcaactgagt tcttgtcaat gactcgtggt tacggtatca tgaaccatac
    39841 cttcgaccaa tacttgccat tgattccagg ggaaattggt ggacgtcacc gtggtgccct
    39901 tgtttctatc gatgctggta aggctacaac ttactcaatc atgtctatcg aagaacgtgg
    39961 tacgattttt gtcaacccag gtactgaggt ttatgaagga atgatcatcg gtgaaaactc
    40021 tcgtgaaaat gacttgacag ttaacatcac gaaggcaaaa caaatgacca acgttcgttc
    40081 agctactaag gatcaaacag ctgttatcaa gacgcctcgt atcttgacac ttgaagagtc
    40141 tcttgagttc ttgaacgacg atgagtacat ggaagtaacg cctgagtcta tccgtttgcg
    40201 taaacaaatc cttaacaaag cagagcgtga gaaagctaac aagaagaaaa aatcagctga
    40261 ataagagcta gaaagagaga aagatggtct atttagtcct aggaatttta ctgctcctac
    40321 tctatgtatt tgcgacacca gaaagcatta aagggacagt caatatcgtc gctatggtat
    40381 gtattttagt ggcactcttg attttattgg ttctatcttt tctgaaaatt tttcaattac
    40441 caacagaaat attcctagca atagccatgt tgatcctagc ttactttagt gtgagagaca
    40501 tcacactcat gccagtcaaa aaaagtaaaa gaagataaaa aagagagttt cggctctctt
    40561 tttgctagga attttataat agtttgaatt gctttttagt taacaccatc tcttttgctt
    40621 gtatagtatg aatgggaaaa acttgaataa aattcgttaa tggcatctat tttatatttg
    40681 cttagtactg gttgcatatt attttgaaat aaaactacta tataatatta ttcatagagg
    40741 caatgtagta aaatatctaa aaaattcgat tttttccttg acaacaaata ataaaaatgt
    40801 tattcttatc acataagaaa gcggtttcaa taaaagagag aggagggttt attttgttgc
    40861 attgttgctc aaggtgtgct ttttttgaaa gaaaaaataa aatgaaaacg aaaaaacata
    40921 gattacttgc tctagctctt atttcaagtt ttacattatt gggagctgca tcagctgctg
    40981 tacaatatcc agatggagga gtatggacgt atggagaagg ttcaggaggt ggttgggctt
    41041 tttcaaatta ctatcatggt aaaaaatatc attattcttc tcttgtaagt agatggaata
    41101 gtcattcaga taaaggagaa gctcctgctg gaaaaacctc ctatgcatgg atttggacta
    41161 aatggggaga acaagtagca ttttactgtg attatgacta atcgttcatt gatttaaatc
    41221 gttccccttg taagaaatta cagggggaat tttgtttaca aggagtctac tatgaagaaa
    41281 ctattcatat tattatcaac tttttttctc agcttcttcc ttgcttggat tattgtctta
    41341 cgtgcgccac aatatttata tgcaagctat gattccgttt ctttacttcg tgtcaaaaaa
    41401 gatactcagg aaccgacgcg tgaggtattt gaacaggaat tggagaattt tgcaaactca
    41461 gaacagagtt taatagctag aagaattgta gagccgagta aggatgggac gactcacttt
    41521 acttatgcaa cttatggtca gggaacttta ccaaaagaat tccaagaagc tagccaagaa
    41581 agtcgtgaac gtagtgatcc gctaaatagt tatctccttt tgtcaggctc cttgacgaaa
    41641 gaaaagcttg ccgataaatt aggagatttg ggttataaag caagtgctga ccgaaagata
    41701 ccgccctatt ttcttgcttt tcgaatatta ctaaatcccc ttattttaat tagtagcaat
    41761 atttggctta tctttctttg ctttagtgat tatcactcgg attaaggaaa tgagagcagc
    41821 aggtataaaa ctcttttctg gtcagactct cttatccatc atggggcatt ctttatctac
    41881 tgatatcaaa tggctccttc tatcagccct cctttccttc ctaggtgggg gagtcgttct
    41941 ttttagtcaa ggtttgtttt atcctatctt gttagccacc tatggttttg ggattagttt
    42001 ctatctgttg tttttattgg cgatttcaat tttactaatg ctcctttatc taatgagttt
    42061 gaattacaaa gcattagttc ccgttattaa ggggagatta ccccttaaac gcctgatgat
    42121 tttaacccta ttgtgtcagt tggttgctgt ctttacagta ggatacgctg ttaagacagg
    42181 tttgacgtct taccaacgat tgaaagaact tgaaatttca aaacaagcat ggcaggatag
    42241 agcagactat tatcaaattt cttttggctt aggtgataga ggaaaagata cagaaaatca
    42301 gagcaagtgg tatgcctttg ccaaggaagc aatcgaagaa gaacaagctc tttatgtaaa
    42361 ggataatctg ctccattttg ccaatccaca aggaaaaaat gaacagggag agacactgga
    42421 tacctatagt ccagatgcta atacgctcta tgttagtccc agttatttgg acaaggaaaa
    42481 ggtcgtggta gatgctgaga ccaaacagaa gttagcccat ctccaaaaag gtgagtttat
    42541 cctcttgctc ccagaacatt tgcgctctcg agaagcagaa cttaagaaaa tttttgaaga
    42601 aagattgagt tattatggaa aatctggtga ggaggcaagt gctcctttgg attatgagat
    42661 gaaagcgcac gttagttatc tttcaatggg agaaaagcgg tttgtttata ataacggtga
    42721 gaatcccgta tccactcagt atttgactga tccgatttta gtggtattca cgccgacttc
    42781 tacaggtgat agttttatat ccttatctag ttggtctatc aatgctggaa aacaactctt
    42841 tatcaaagga tatgagagtg ggctagaact cttgaagaaa gctggaattt atgagcaagt
    42901 atcctatctt aaagaaggaa gaagtgttta tctaactcgt tataatgaag ttcaaactga
    42961 aacagcaact ttaatcttag gagctattgt ggggatagct agttccttgt tactatttta
    43021 ttctgtcaat cttctatatt tcgagcaatt ccgccgagat atcttgatta aacgaatttc
    43081 aggtttacga ttttttgaaa cacatgctca gtatatggtt agccaatttg ccagttttgt
    43141 atttggtgct agtctcttta ttttaagcag tcgagacttg gtgattggct tgctcacttt
    43201 attggtcttt ctagctagtg cagttttgac gctttaccgt caagcgcaga aagaatctcg
    43261 tgtttctatg acaattatga aaggaaaata ggatgattga actaaagaat atatctaaaa
    43321 aatttggaag ccgtcagcta ttttcagata tgaatcttca ttttgaaggt gggaaaattt
    43381 atgccttaat cggtacaagt ggctgtggta agacaacact cttgaatatg attggacgat
    43441 tagagccata tgacaaaggg caaatcatat atgatggcac ttctcttaag gacattaagc
    43501 cttctgtttt ctttagagat tacttaggat acttatttca agattttggc ttaattgaaa
    43561 gccaaaccgt caaagagaat ctcaatctgg gtttagttgg taaaaagttg aaggaaaaag
    43621 agaaaatctc tttgatgaaa caagctctaa accgtgtaaa cctctcttat ttggatttga
    43681 agcaacctat atttgagtta tcaggaggag aagcacaacg tgttgcacta gcgaagataa
    43741 ttttaaagga tccacctttg atcctcgcag atgaaccaac cgcttcctta gaccccaaaa
    43801 actctgagga attactttcc atcctagaat ctttaaaaaa tccgaatcgg accattatta
    43861 ttgcgaccca taatcctctg atttgggagc aagtggatca ggtcattcga gttaccgatt
    43921 tatcacatag atgatatggt aagattcagt tagaagaaag agtcacaaac acactttgtg
    43981 gcttttttat ttccataaaa atggtaaaat agtaggagta gaaatggagt tcgagacatg
    44041 aaagtaatag atcaatttaa aaataagaaa gtccttgttt taggtttggc caagtctggt
    44101 gaatctgcag ctcgtttgtt ggacaagcta ggtgccattg tgacagtaaa tgatgggaaa
    44161 cctttcgagg acaatccagc tgcccaaagt ttgctggaag aagggatcaa ggtcattaca
    44221 ggtggccatc ctttggaact cttggatgaa gagtttgccc ttatggtgaa aaatccaggt
    44281 atcccctaca acaatcccat gattgaaaag gctttggcca agggaattcc agtcttgact
    44341 gaggtggaat tggcttattt gatttcagaa gcaccgatta ttggtatcac aggatcgaac
    44401 ggtaagacaa ccacaacgac tatgattggg gaagttttga ctgctgctgg ccaacatggt
    44461 cttttatcag ggaatatcgg ctatccagct agtcaggttg ctcaaatagc atcagataag
    44521 gacacgcttg ttatggaact ttcttctttc caactcatgg gtgttcaaga attccatcca
    44581 gagattgcgg ttattaccaa cctcatgcca actcatatcg actaccatgg gtcattttcg
    44641 gaatatgtag cagccaagtg gaatatccag aacaagatga cagcagctga tttccttgtc
    44701 ttgaacttta atcaagactt ggcaaaagac ttgacttcca agacagaagc cactgttata
    44761 ccattttcaa cacttgaaaa ggttgatgga gcttatctgg aagatggtca actctacttc
    44821 cgtggtgaag tagtcatggc agcgaatgaa atcggtgttc caggtagcca caatgtggaa
    44881 aatgcccttg cgactattgc tgtagccaag cttcgtgatg tggacaatca aaccatcaag
    44941 gaaactcttt cagccttcgg tggtgtcaaa caccgtctcc agtttgtgga tgacatcaag
    45001 ggtgttaaat tctataacga cagtaaatca actaatatct tggctactca aaaagccttg
    45061 tcaggatttg acaacagcaa ggtcgtcttg attgcaggtg gtttggaccg tggcaatgag
    45121 tttgacgaat tggtgccaga cattactgga ctcaagaaga tggtcatcct gggtcaatct
    45181 gcagaacgtg tcaaacgggc agcagacaag gctggtgtcg cttatgtgga ggcgacagat
    45241 attgcagatg cgacccgcaa ggcctatgag cttgcgattc aaggagatgt ggttcttctt
    45301 agtcctgcca atgctagctg ggatatgtat gctaactttg aagtacgtgg cgacctcttt
    45361 atcgacacag tagcggagtt aaaagaataa tatgaaaaaa attgtcttta caggtggggg
    45421 gacggttgga cacgttaccc tcaatctttt gttaatgccc aagttcatcg aagatggttg
    45481 ggaagtccac tatatcgggg acaagcgtgg tatcgaacac caagaaatcc ttaagtcagg
    45541 tttggatgtc accttccatt ctattgcgac tggaaaattg cgtcgctatt tctcttggca
    45601 aaatatgctg gacgtcttca aagttggttg gggaattgtc caatcgctct ttatcatgtt
    45661 gcgactgcgt ccacagaccc ttttttcaaa ggggggcttt gtctcagtac cgcctgttat
    45721 cgctgcgcgt gtgtcaggag tgcctgtctt tattcacgaa tctgacctgt ctatgggctt
    45781 ggccaataaa atcgcctata aatttgcgac taagatgtat tcaacctttg aacaagcttc
    45841 gagtttggct aaggttgagc atgtgggagc ggtgaccaag gtttcggaca aaaacactcc
    45901 agaaccagat gaattggtgg atattcaaac ccactttaat cccaaattgc caactgtatt
    45961 gtttgttggc ggttctgcag gcgctcgtgt ctttaaccaa ttggtgacag accataagaa
    46021 agaactaaca gagcgctaca atattatcaa tctaactgga gattctagcc tgaatgagtt
    46081 gaggcaaaat ctttttcgtg ttgactatgt gaccgatctc tatcaaccct tgatggaatt
    46141 ggctgatatt gttgtgacac gaggtggtgc caatacgatt tttgagctct tggcgatagc
    46201 aaaattgcat gtcattgtgc cgcttggtcg tgaagctagt cgtggtgacc agattgaaaa
    46261 tgcagcttac tttgtaaaaa aaggctatgc agaagacctt caagaaagcg atttgacctt
    46321 ggatagtttg gaagagaagc tttctcactt actaagtcac aaggaagatt accaagctaa
    46381 gatgaaagct tctaaggaat tgaaatctct agcagatttt tatcaattgt tgaaaaaaga
    46441 tttatcataa ggaaagtaaa tgtcaaaaga taagaaaaat gaggacaaag aaaccctcga
    46501 agaattgaaa gagttatcag aatggcagaa acgaaaccaa gaatatctaa aaaagaaggc
    46561 tgaagaagag gcggctctag ctgaggagaa ggaaaaggaa agacaagctc gaatgggaga
    46621 agaatctgag aagtcagagg ataaacagga ccaggagagt gaaacagacc aggaagattc
    46681 agaatcagct aaggaagagt ctgaagaaaa agtagcatcc tcagaggctg acaaagagaa
    46741 agaagagaaa gaagaatcag agtctaaaga gaaggaggaa caggataaaa agcttgctaa
    46801 aaaggctaca aaggaaaaac cagccaaagc aaagattcct ggtatccata tcttgcgagc
    46861 cttcacgatt ttatttccaa gtctgctttt attgattgtc tctgcctact tgctcagtcc
    46921 ttatgcgacc atgaaagata ttcgtgttga gggaacggtg caaactacag ctgatgatat
    46981 tcgacaggct tcaggcattc aggattcgga ttatacgatt aaccttctgc tagacaaggc
    47041 aaaatatgaa aagcagatta agtctaacta ttgggttgaa tcagctcaac ttgtctatca
    47101 atttccaact aagttcacta ttaaggtcaa ggaatatgat attgtggcct actatatttc
    47161 tggtgaaaat cattatccta ttctttccag tggtcagctt gagactagtt ctgtgagtct
    47221 gaacagttta ccagaaactt atttatcagt tctctttaat gatagtgaac aaatcaaggt
    47281 ttttgtctca gaacttgctc aaattagccc agaactcaag gcgactatcc aaaaggtgga
    47341 attagcccca agcaaggtga catccgattt aattcgattg accatgaatg attcggacga
    47401 agtcttggtt cctctatctg aaatgagtaa gaaactgcca tattacagta agattaagcc
    47461 tcaattgtca gaaccgagtg tggtcgacat ggaagctgga atctacagct acactgtggc
    47521 ggataaatta attatggaag ctgaggaaaa agccaaacaa gaggccaagg aagccgagaa
    47581 aaaacaggaa gaagaacaga aaaaacaaga ggaagagagc aattgaaatc aaacgaccca
    47641 gcgctcattg cgtcgctagg tttacctttt ctcttatagt tctttagtga ccatgttttt
    47701 acttgacaag tgctagtaga aataatagaa tagtaaaaaa cctttaaagc agtccagaga
    47761 ggcagctaag gttagacggt gaaagggtgg agactaccca tttttcgtgg aaccttgctg
    47821 ttggcaggtt ccttttttcg tggcttctgt tggccagact ctctcactag taaaggtaaa
    47881 aggagaaacc tatgcgagaa catcgtccag tcattgctct tgattttcct agttttgagg
    47941 cggtcaagga atttttagct cttttcccag cagaagaaag cctttatctc aaggtaggga
    48001 tggagcttta ttacgcagcg gggcctgaga ttgtgtccta cttaaaaggt ttgggtcata
    48061 gtgtcttttt ggatctcaaa cttcatgaca ttcctaatac agtcaagtca gccatgaagg
    48121 tcttgtctca gcttggtgtc gatatgacta atgtccatgc ggctggtggt gtagagatga
    48181 tgaaggcggc gcgtgaaggc cttgggagtc aagctaaatt gatcgctgta actcagctca
    48241 catcaacgtc agaagctcag atgcaggagt ttcaaaatat ccaaaccagt ctgcaagagt
    48301 ctgtgattca ctatgccaag aagacagctg aagctggctt ggatggtgtt gtttgctcgg
    48361 ctcaggaagt acaagtcatc aagcaggcta ccaatccaga ttttatctgt ctgacaccag
    48421 ggattcgtcc agctggtgct gcagttggag atcaaaaacg agtcatgaca cctgctgatg
    48481 cctatcaaat cggcagtgac tatatcgtag tgggacgtcc cattacccaa gctgaggatc
    48541 ctgttgcagc ttatcatgcc atcaaggatg aatggacaca ggactggaat taaagaacta
    48601 gattagaaaa ataaaaggag aataccatga cacttgctaa agatatcgct agccacctct
    48661 tgaaaatcca agccgtttat ctcaaaccag aggaaccctt cacttgggca tctggtatca
    48721 agtcaccgat ttacactgat aatcgtgtga cactagccta tccagaaact cgtaccctaa
    48781 ttgaaaatgg ttttgtggat gctatcaaag aagcctttcc tgaagtagaa gtgattgcag
    48841 gaactgcaac agcagggatt ccacacggag ccattattgc tgataagatg gatttgcctt
    48901 ttgcctacat ccgtagcaaa ccaaaagacc acggagctgg taatcaaatc gaaggtcgcg
    48961 tagctcaagg tcaaaaaatg gtagtggttg aagaccttat ttcaacgggt ggttcagttc
    49021 ttgaagctgt agcagcagcc aagcgagaag gagcagatgt gcttggagtt gtagcgattt
    49081 tcagctacca attgccaaaa gcagataaga actttgcaga tgctggtgtt aaacttgtga
    49141 cgctttcaaa ctatagcgag cttatccatc tagcccaaga agaaggttac atcacgccag
    49201 agggccttga tcttctaaaa cgctttaaag aagaccaaga aaattggcaa gaaggttagg
    49261 tcagtaagat aaagagagac gaggctaccg agcctctttt accattttat ttaaaatatg
    49321 acaatatttt aaataaaata attgacaacg ctttcttttg ttgatataat gaaaatgtaa
    49381 tatgtatcaa attgatcaat caactatctt gtttatcact tcttaggagg acgatgtcat
    49441 gaaaagaaga aaaatatatt ccttttttgc gtagttacaa ttgtatctag tttgtttctc
    49501 cctacagttt tagctagaca gattggagat tatgatttaa cgttgccgcg ttggggttcg
    49561 gatacaacta gtgagcttga gaaagaaaac gcctctgctg gaattaataa tagtgacagc
    49621 actggtggcg gtaaaaggtt aaatacctct attcgtagcg cctatagtgg gtcagatatt
    49681 accccggtat attcattggg gtctggctct aggattgtca tgtactataa tggaggtggt
    49741 gacaattata ttggttctgg tactagatta gctatggcgc cacaatttgg aaatcatgta
    49801 agaattcata cttcaggttc ttggagtcca gattcttatt aacttacttg tcagagtaag
    49861 ccttaaagat ggttgattgt gggtgtagca tgaaaaaaga atgctacacc ctatttttat
    49921 tataaggagg agtaaggatg gaatttttca tttgtaatct tgtacgagtc gttcaatcac
    49981 ctcgatttta tatgtcttta tttttgaccc ttctttgcat gagtttagga aatttccttg
    50041 ctttcaatgg tatttataaa attgaaggtt tatcgatttt ttttgccgct tcttctattc
    50101 gaggattttc accgattagc ctagtagctg cacttatctg tacactgccc tattctagtc
    50161 agataataga ggatgctgag agtcattttc taacagcaca attgtgtcga atttctaaaa
    50221 agaagtatct ggctattgtg ggtagtactg taattatttc ttcttttcta gtcttttttc
    50281 tcccctattt attattatta ggaattaatc ttttagtgac tccttatcag gaaatttata
    50341 ttggagatta tagtggtgcc ttaaaagaat tatttgattc caatcagttg ctctatagtc
    50401 ttgtgacgac tctctggtat ggagtttggg gcgctgtgtt ctctattttt ggactagcta
    50461 gtgctttgct agtgaagaaa aaattaggag ctattttcat cccagttgcc tatatgatgg
    50521 ttggtggtat tttatgggct attttagggc tatcttactt agaacctgtg acaacgctag
    50581 ctttgggata tcagaaagat atcagtcttt ccttagttag tgctcatctt gcttttattt
    50641 tatttgttag ttgtttggtt gtttatggta cattttttct acattcagag gactatgtat
    50701 aatgaaacaa tttgttcaat tttataaaaa agatttctta gcagtattgg tttattttat
    50761 attactgcta tcctgtgttt tatctagtac agtatattta ttgcgctgtc gccaatattc
    50821 aatccatcca aatgtattag aatggatctt agttttactt caagatatga cgactggagt
    50881 atattgcttt ccgttcacat atatattgtt ctttttttat ttgatgaata actattttaa
    50941 taggttggag tgtcgcattc gtctgaaatc aattaagcac tttaccagtt ttagtttcaa
    51001 attagcagct cttagtacgg ggatttggac ggcgacttta tttttattga tttttctaat
    51061 tgcatttagt aatggtttta gcttctcttt ggagataaag gaggttgatt ttttaagaga
    51121 attttatggt ataagtattg caaacaatgc tagtttcttt ataggatttt ttttctctta
    51181 tatagcatac tatttctttt tatccttact tactattagc agtttttctt ggtttaaaaa
    51241 atcaaacatg agcttagtat ttctgtttac ttttttattt gtagaatcct tattctggat
    51301 ttatcagttg gacaatggga taattggatt attgccaatt tttcagtata tggtaaattc
    51361 caatccgtat gcattgattt attggcttac attactatct atcataattc cattgactgt
    51421 attttctgtt catagaaact ggaggagagt gtaaaagttg gaaatgggaa agttaagtag
    51481 tcacatgtgg aggttgaatc agataatcta taccaagtac ttttggggtt atgttctttt
    51541 ttggatattg atttgtttag gattatggta ttggttagaa ggaaatgata gacttgttat
    51601 agaaatttta aaagggccta atctgagtca aaactctttt ttagtcttat ctatatggtt
    51661 gcttcattgg tttattattc atacattttt tctagcagtt gtatatcgta gaagagcatc
    51721 cgatttcttt atggaagtga ttcgattttc ttctattaag ctctggatta ggtatcagat
    51781 ttggacctgt tttctttatg gactcatttt aatcatggta aaagttctag tgattcaatt
    51841 tatgttacag ttaccaaact gggatatagg agttttgttt atagttgatt ctttgaatgc
    51901 ttgtgtgtta gtcttgtttt gctttatgtt atacgcacta ggagcgaatg tacaaatgaa
    51961 ctttgcttgc gttagtttct ttttactcat gattgtgttt ggtggtctat ttgtaggaaa
    52021 tcgaactaat tatctatttt atattttgaa tcgagggaat ggagatatag gacgagattt
    52081 atttcttcag ttgctatttt tagtctttct ttttaaaagt attttctatt tcactcgtca
    52141 aaagaggagg tttatagaat gaatgaaata atcatattaa aaaatattga gttgaaatta
    52201 aaaaaaacat gtgtttttca aaaccttaat tttagttgta aacaggggga aattatagga
    52261 attactggtg cgaatggctc agggaaaagt gtattgttta aattaatagc tggtttatat
    52321 agtccgtctt atggagaagt gttaatcaat ggggaaaata ttgttcctga gagaaaaatt
    52381 ccagctaatt tgggagcttt gattgaagaa cctggtttta taaattatta tagtggcttt
    52441 aagaatttac aatatttggc aagcatacga ggagtagttg gtaatcagga aatcaatgat
    52501 acactgaaaa tagttggtct atatgagcaa aaagaccaga aagttaaaac ttattcgcta
    52561 ggtatgagga aaaagctagg gattgctcaa gcaattatgg agaatccctc tattctttta
    52621 ctagatgaac ctatgaatgc cttggataaa tcaagtgtag aaaatatgag aacattgttt
    52681 agaaagctct ctagtgaaaa agggacaaca attttgattg ctagtcatag tgaagaggat
    52741 attcgtatct tatgtgataa agtatatgca atagaagata aagtatgtac actgtgttca
    52801 gattgaacat cttagataga ctcaggatgt tataggtaaa atcttaaaaa gggattggag
    52861 cttaaaatcc agtccctttt aagagttaat ggccaccttc aacaaccagg tcatctgctt
    52921 tagcagcgtc accgtaggtt gggtgaagtg ttttttcata ggccttgtgg aagaagtttt
    52981 ccttgcctaa tttttcaata tctttattga tgaagtctag caattcttgg ttgccttttt
    53041 gaactgctgc cgcaatggta tcgggatcac cgagggaagt aattcctact tcaaatcctt
    53101 tattttcaag tgcccaagct agaacttccg tattgtcagt tgaaaaggca tctccacgtc
    53161 cgtcaagaag agcttggtaa gagtcactgt attggtcgta tttttggagt ttgatttctg
    53221 gatgattctt ttcaaaataa gtctcagcag tcgttccttt tgtgacaatt aaggttttac
    53281 cttcaagttg tttgacgtct gtaatgagac cagtcttagg tgatacgaca cccagagaaa
    53341 ctttcatata tggaagggca aaatcaactt gtttcttacg ttcgtcagtt actgtaaagt
    53401 tagcaagagt aatatctacc ttgtttgaaa tcaagtattc cgcacggttg gcagcatcga
    53461 ctgaaatgta tttaaccttg acaccaaggt cttgagctag ttggttccct agttcaatat
    53521 cgtagcgtag ccttggtaag aaccatcatt gtcaacgtag ccaaacggtt ttttatctcc
    53581 aaacacggcg attcgcagtt caccgctttt tttgatttca tcgatagtgc gagctttggc
    53641 agttgttttt ccagaggatg aaccagcgtt tccacctgag ctacaagcag tgataaagat
    53701 aagggcaaag gcaagtgcta aaacagttaa gagtggtttg aatagtttca taagaatctc
    53761 ctttatagat atgagccgaa ttggctaaag tcaaagacgt ttaaaaattc ctgggctcgt
    53821 ttggtttgcg gattggtaaa gaaggcttga gctgttcctt cttcagcgat tttcccttgg
    53881 tcgaggaaga taatccggtc agtaatggct tgggcaaact gcatttcgtg ggttactaaa
    53941 atcatggtac ggccttcttg ggccaaatca ttgataagtt ccagcacctc acgcaccatt
    54001 tctggatcca gcgaagcagt cacctcgtca aaaaggatga tttctggatg cattaggagg
    54061 gcacggacaa ttgcaacacg ttgcttctgt ccaccagata attgacgggc aaagctatgt
    54121 tgtttatcca gcaaaccgac acgatctagt aattgcaaag cttcttccgt tacttctttc
    54181 ttgtcccatc cttgagtttt gatagggcct aggatgaggt tttgtaagac atccagatgg
    54241 ggaaagagtt cataacttta aaagaccatg ccaatctttt ggcgaactag gtgaaaatct
    54301 tttttatttt caacgataga ctgaccatcc agaagaatat ctccaccttg aatactttct
    54361 aagccgttga ggcaacgaag gagggtactt ttcccacaac cagatggccc taggatgaca
    54421 acaacttccc cttttttgat ttctagagaa agtccttgga ggatgggatt gtctccgaag
    54481 gattttttta gttccttgat ttctaagata gtttcagaca tttagtttct ccaatgtttt
    54541 tctaagtgag tggatagttt ggaaataggg tagcaaactg cgaaatataa gattagaatg
    54601 gttccataaa tccaaaatga agcagttggg atggtcaggc gattgctatc gatgatttgt
    54661 tgtccaactt tggtcacttc cacaacccca atcaaaacaa ctaatgaagt ggttttaatc
    54721 atccgagtga caagattgat agcctgcggt agcagtcttc tcaagacttg tgggatgatg
    54781 atgtggtagt aaagttgaac attagtcaag ccgagtgcct gtccactttc aaactgatgt
    54841 ttagggagag aagtgatagc tccacgtacc aagtctccca tttcagctgt tccccagagg
    54901 gtaaaaacga taataactga agtctcacct gagatattga tattaaagtt tcgagccaag
    54961 ccaaagtaaa cgatgaagag tagcaccagc tggggcatga tacggataaa ttccagatac
    55021 aatcgtgtta aaaatcgtat gattctagaa tgggaggtca tgatgattcc catgactgtt
    55081 ccgaacatca tggataagag gacagacagg atggatatcc caatcgtaac gcccaatccc
    55141 tgtaagattc tcaggaggtt atttccttga aagagtactt ggattcccga atcctgcatg
    55201 gcggagcctc ctaaaaagac aagcccaagc gttgcacaga cttctgaaga taggacaatc
    55261 ccgattcggg gaagaccgaa gtagagaaag aagagttgaa tcaaaagggg cgtattacgt
    55321 gacaattcaa tgtaggctgt cgctacttgc gccaaaacag ggattcgata atgtcggatg
    55381 atactaacga ttaaaccgag cagaaaggat cccaaacttc cccaaactgc aatatacaaa
    55441 gtaaacgctt acttatcaag gagggcattt tatgtcatac aaaacaagca atgcagaagg
    55501 tcatgtagat ttcatcaata cctatgattt ggagccaatg gcgcaacaag ttattcctaa
    55561 agcagcattt ggctatatcg ctagtggggc ggaagatact ttcacttctt tccagtgatt
    55621 ttagcgtcag gttcttttta gtttttaaag attatccgtg aatttcttgc ttatttatga
    55681 taaaatgggg gtatcgcaaa aaatgactca tcgtattcaa ttttgagtaa aactaggagg
    55741 atcccatgtc tacagaacat atggaagaac taaatgacca gcagatcgtt cgccgtgaaa
    55801 aaatggctgc gctccgcgaa caaggaatcg atcctttcgg aaaacgtttt gaacgtactg
    55861 caaattcaca agaattaaaa gataaatatg ccaacctcga taaagaacaa ttacacgata
    55921 aaaacgaaac agctactatc gcaggacgct tggtaaccaa acgtggtaaa ggaaaagttg
    55981 gttttgccca ccttcaagac cgcgaaggcc agattcagat ctatgttcgt aaggatgctg
    56041 tcggtgaaga aaactacgaa atcttcaaaa aagcagacct tggtgacttc cttggtgtcg
    56101 aaggtgaagt gatgcgtacg gatatgggag aactctctat caaggcaacc cacatcacac
    56161 acttgtctaa ggctcttcgt cctcttcctg agaaattcca tggtttgaca gacgttgaaa
    56221 caatttaccg taaacgttac cttgacttga tttctaatcg tgaaagcttt gaacgctttg
    56281 tcactcgttc aaaaatcatc tctgaaatcc gtcgttacct tgaccaaaaa ggattccttg
    56341 aagtggaaac acctgttctt cataatgaag ccggtggtgc tgctgcccgt ccatttatca
    56401 cccaccacaa tgcccaaaac attgacatgg tgcttcgtat cgcgactgag cttcacttaa
    56461 aacgccttat cgtgggtggt atggaacgtg tctatgaaat tggccgtatc ttccgtaacg
    56521 aaggaatgga cgctactcat aaccctgagt ttacttctat cgaagtttac caagcttatg
    56581 cagatttcca agacatcatg gacttgacgg aaggcattat ccaacacgct gctaaatcag
    56641 tcaaaggtga tggcccagtc aactaccaag gtactgaaat caagattaac aaaccattta
    56701 agcgtgttca tatggtggat gctatcagag aaattactgg tgtcgatttc tggcaagaca
    56761 tgactttgga agaagctaaa gctatcgctg ctgagaagaa agttccagtt gagaaacact
    56821 acactgaggt tggtcacatc atcaatgcct tctttgaaga gtttgtcgaa gaaactttaa
    56881 tccaaccaac ctttgtctat ggacatccag tagctgtatc tccactcgct aagaaaaatc
    56941 ctgaagacca acgctttact gaccgtttcg agctctttat catgactaag gagtacggta
    57001 atgcctttac tgagttgaac gacccaatcg atcaacttag ccgttttgaa gcccaagcta
    57061 aagctaaaga acttggtgat gatgaagcga caggcatcga ctatgactac atcgaggctc
    57121 ttgaatacgg tatgccacca acaggtggtt tgggaatcgg tatcgaccgt ctctgcatgc
    57181 tcctcactga tacaacaact atccgtgatg tattgctctt cccaacaatg aaataaattc
    57241 ttaccctctg gctcttacca ggggattttt tgattcaaaa agagactgaa tttaaggaga
    57301 aaatgaagtg tagtatattg aagttgaaat agtacacttt gatttctaag acactgttag
    57361 aaattggttt aaattcccta atcaatttgt gcatgtttta tttcatttta cgatagtacg
    57421 ctgaaactgt tcaaaaagta ctagaaattg acttggattc cccaattgat ttgttcagat
    57481 tcactataaa taaaaaatta ataagtggga taggaagtta gcgtcaacta ggatagtatc
    57541 ttgcttaaac agtatatatg ggactgatat aagtccatag gtcctattag aggatgttct
    57601 ggtgtcttat tcacttgttt ttttatagta ttagtagata gaatccgcaa ataaaaaagt
    57661 agttcaaatg cctggcagca aaaaatctca acgattcact taatatagac taaagtttag
    57721 agtttaagga aagtagggct agtatattgt atgaaaaaat aagatggttt ttaagcaaaa
    57781 ctcttgaaaa tgattgaaaa aagagttatt atagttgtgt agtaaaaagc aaacgcttac
    57841 ttaatcaagg agggcatttt atgtcataca aaacaagcaa tgcagaaggt catgtagact
    57901 tcatcaatac ctatgatttg gagccaatgg cgcaacaagt tattcctaaa gcagcatttg
    57961 gctatatcgc tagtggggcg gaagatactt tcactttaag agagaatatc cgcgccttta
    58021 accacaaact catcgttcct catacacttt gcgatgttga aaatccaagt acagagattg
    58081 aatttgcagg tgaaaaacta tcttcaccaa tcattatggc gcctgttgcg gcccataaat
    58141 tggcaaatga acagggggaa gtggcgactg cgcgtggtgt gcatgagttt ggttctcttt
    58201 atacaaccag ttcttactct actgttgacc ttccagagat ttctgaagcc cttcaaggga
    58261 cacctcattg gtttcaattt tactttagta aggatgacgg tatcaaccgc cacatcatgg
    58321 accgtgtgaa ggctgaaggt tataaagcga ttgtcttgac ggcagatgct actgtagggg
    58381 ggaatcgtga agtggataag cgtaatggtt ttgtcttccc agttggcatg ccgattgttg
    58441 aagaatacct gccagaaggt gctggtaaat caatggactt tgtttacaaa tcagctaaac
    58501 aacgcttgtc tccacgcgat gtagaattta tcgctgaata ctctggtctt cctgtgtatg
    58561 tcaagggacc acaatgccgt gaggacgttg aacgttcact tgctgcagga gcttctggta
    58621 tctgggtaac caaccacggt ggtcgtcaaa tcgacggtgg accagctgcc tttgactcgc
    58681 ttcaagaagt ggcagaagca gttgatagac gtgtgccgat tgtctttgac tctggtgttc
    58741 gtcgtggtca acacgtcttt aaagccttgg cttcaggagc agacttggta gctattggtc
    58801 gccctgttat ttatggcttg gctctcggtg gtagtgtcgg tgtgcgtcaa gtctttgaac
    58861 acttgaatgc ggaattgaag acagttatgc aattgtctgg agctcagacc attgaagatg
    58921 tcaaacactt taagctccgt cacaatccat acaacccaac cttcccagtt gaccctcgtg
    58981 acttaaaatt gtattgataa aacagattgc ctccactgaa tgtggaggtt tttcttcgtg
    59041 tattggaaga ataaatcgct atcgaaaact ataataaaat gaaataagaa taggacaaat
    59101 taatcaggac agttaaatcg atttctaaca atgttttaga agtagaggtg tactattcta
    59161 gtttcaatat attatatata aagatatttt tcggtcaaat atcttgctag ggctttcatt
    59221 ttttgctata ctggttcagt aattaaataa tagagacatt tggggtgctt taggctgaga
    59281 taatacccat tgaacctgat acagttaaga ctggcgaagg gaaatgtgaa cagttttttc
    59341 gtatggtgaa atgaacggtc taatcttgta agtcaactct aattcttgat tgtaattgga
    59401 gttttttgtt tatataaact ggataggctt gtttagttag ctctctgcaa atgctctcga
    59461 tgtgctttaa aaggatcaag tggaattacg attttgcttg atatttcttg gtgttttatt
    59521 aattactaac aagtaaagag aggagaagta aatatggaaa cacaagacta tgcatttcag
    59581 ccaggtttga ctgttggaga attattaaaa agcagtcaga aggattggca ggctgcaatc
    59641 aatcatcgtt ttgttaagga actttttgcg gggacaattg agaataagat cttaaaggac
    59701 tatctgattc aagattatca cttctttgat gccttcttat ccatgctggg tgcctgcgta
    59761 gctcacgcag ataaacttga atccaagctt cgttttgcca agcaactagg ctttcttgaa
    59821 gcagatgaag atggttattt ccaaaaggct tttaaagagt taaaagtagc agagaatgac
    59881 tatctagaag tgactttgca ccctgtaaca aaagcctttc aggatctaat gtattcggca
    59941 gtggcttcat cagactatgc ccatcttttg gttatgctgg tcattgcaga aggtctctat
    60001 ttagactggg gttctaaaga tttggctcta cctgaagtct atattcattc ggaatggatc
    60061 aatctccaca gaggtccttt ctttgcagag tgggttcaat ttctggttga cgaactcaat
    60121 cgtgtcggta aaaatcgaga agatttgaca gaacttcagc aacgctggaa tcaagcagtc
    60181 gctttagaat tagctttttt tgatattggt tacgatgtct agagaaggct catgatattt
    60241 acaaatttga tgaggtaaga ctcttcgaaa atctcttcaa accacgtcag ttctatccac
    60301 aacctcaaaa cagtgttttg agctgacttc gtcagtctta tctacaggct caaagcagtg
    60361 ttttgagcaa cctgcggtta gcctcctagt ttgctctttg attttcattg agtataaatc
    60421 attcaatgta aatgaaaaaa attcttaacg aaagatagaa ataaatcgaa atcagtagat
    60481 cgtataaagt gaaaaggaag gatttcaata tgacaagttt aaaattatta aaagaaaaag
    60541 caccattggt catttgtata accaatgatg tagtaaaaaa tttcacagca aatggattag
    60601 tagcactggg cgcctcacca gccatgagtg agtttccagc agatttagag gatttgttaa
    60661 agtatgctgg tggtttatta ataaacatag gaacattgac agatgaaaat tggaaattat
    60721 accaagctgc tctgaaaatt gcggagaaat ataatgtccc agcagtttta gatcctgtag
    60781 cctgtggagc aggagaatat agaaaaaaag tagcggatga tctaatcaac aattataaac
    60841 tagcagcgat tagaggaaat gctggcgaga ttgcctcttt agtaggaata gatgtggcat
    60901 ctaaaggagt agatagtgcg ggcgtagata atattgacga aattgctcta gcagcaaatg
    60961 agaagttcaa tattccaata gtagtaacag gtgaagtgga tgccattgct gttaatggag
    61021 aagtggtaac gattcataat ggtagtgcta tgatgccgaa agtcattggg acaggatgct
    61081 tattaggagc tgtagtagca agctttatcg gactagaaaa aggtcaagaa ttgaaatcat
    61141 tagaaacagc aatgttggtt tacaatatcg ctggagaaat agcagaaaaa cgtcccaatg
    61201 gacatcttcc tggaacattt aaagctgaat ttataaatgc cttatacgag attacagatg
    61261 aagatgtaaa ggaattcaaa agagtgaagt aagatgtttc ataaagaatt actaaaacta
    61321 tattttattt gtggaacgac tacttgccaa ggaaaaaatc tatatacagt cgttgaggaa
    61381 gccttaaaag gtggtataac cttatttcaa tttcgagaaa aaggtgaggg tgctttagaa
    61441 ggcttagaaa aacttgagct agctatccaa attaaagaac tttgtaaaaa atacaatgtt
    61501 ccatttatcg ttaatgacga tatagattta gcaatggaaa ttgacgccga tggcgtacat
    61561 gtaggtcaag atgatattgg tgttgatgaa attagaaaat tgatgccaga taaaataatt
    61621 ggtctttcta taagaaacga agaagaattt caacaatcaa aagttgaata tgtagattat
    61681 gtaggtgttg ggcctgtatt tgatacccag tcaaaagatg atgctggtgg tgctataggt
    61741 tatgaaggtc ttgaattgat gagaaaacta ttgccacaaa tgcctttagt tgcaattggt
    61801 gggatacaga cgaaacatat taaagacatt ataaagacca atgttgacgg cgtttcaatc
    61861 atttcggcaa tatcgtatgc aaaaaatata gaaaaaactg ttcgggaaat gagtgaacaa
    61921 tagatatcta tccttggatt ctaagtaagt aggattttcc ttttttaaaa agctatgtct
    61981 agattcagct tgaatggcta attcatcaaa caggtcattt gttttttgca aaagaaagat
    62041 ctgctgtctt tgtgagtgca aggctgtatt tccagttcaa tttcttgaac tagtataaaa
    62101 tgtgtgttat aataatcaca taattaaata ataaaggcat ttggggtgct ttaggctgag
    62161 atgataccca ttgaacctga tacagttaag actggcgaag ggaaatgtga aatgtttttt
    62221 tcgtatgtcg aaaagaactg tctaatcttg taagctgaac tctaattcgt atctgtaatt
    62281 agagtttttt cttttacgaa actggatgaa gatgatatag tagattgaaa taagatgcga
    62341 acaaatcaat tagaaaattc aaattaattt ctagaaatat tttagcattc ctgtgtactg
    62401 ttctaaattc aatctgctat acaaagtatt taggtcggtc ttcttgagtg ccccactttt
    62461 cttttaaaaa aggagttttt tatgttgaaa aaatggcagt taaaagatgt tatcttgctt
    62521 gctttcttgt ctatcttttt tggtggggtt ttcgttggtt caggatatgt gtataatatt
    62581 ctcagtctac tcttaacacc tcttggtttg caggcctttg ccaatgaaat cctcttcggt
    62641 ctctggtgta tggctgcgcc cattgctgcc atctttgttc cgagagtcgg aagtgcaacg
    62701 attggagaag tgctagctgc gcttgctgaa gtcctttatg gtagccaatt tggtctagga
    62761 gctcttttgt ctggcttggt tcaaggtttg ggaagtgaat ttggttttat cgtaactaag
    62821 aatcgctatg aaagttggct ctctctaact gctaatagta ttgggattac gcttgttagc
    62881 tttgtctatg aatacattaa gttaggttac tacgcctttt cccttccgtt tgtcctttcc
    62941 ttacttgtgg tacgttttat ttctgtttat ttcttctgta ccatcttggt tcgtgccatt
    63001 gtcaaactct atcatcagtt tgcaactgga ggaaaagcat agatgggtct ggaactacga
    63061 gcgattcagt ccccaatctt ctctgagccg tttgatttta cttttcatgg gcaagccttt
    63121 accttgttag ttgggagcag tggttcagga aaatccagcc tttttcaagt cattgcccaa
    63181 gtcagttctc ttccctatag tggtcaagtc ctgatagatg ggagcgaggt tagtcagctt
    63241 tctatcatcg cacgtgtcca gaaggttggc attctctttc aaaatcccaa tcatcaattt
    63301 accatggaga acttgtttga ggagctgatt ttcaccttgg agaatatcgg ctatcacctt
    63361 caggaaattg attctaaaat agcagaggtt gtccagcaat gtcgttgcaa ggacatcttg
    63421 caccgtctca tccatcactt atcaggtggg gaaaagcaaa aggcggcctt ggctgttctc
    63481 tttgctatga atcctagggt ctatctatta gatgagccct tcgcttccat tgaccgcaag
    63541 agcagaatcg agatattgga gattctaaaa gagttggctc ttgatgggaa gacagttatt
    63601 ttgtgcgacc atgatttatc tgactataaa gcctatatcg accatatggt tgagctaaga
    63661 gacggaaaac taagggaagt gtttcaaatc ccttcctatg agatgacaca ggttgcttca
    63721 aaggaagttg cttctagccc ggaactattc catatgaacc gtgtgactgg tgagcttggt
    63781 aatcgccccc tcttttcaat tgctgatttc acattctatc aagggatttc ctgtatcctg
    63841 ggtgacaatg gtgtcgggaa atcaaccctc tttcgctcta ttcttcaatt tcaaaagtat
    63901 aaggggcgca ttgcatggaa ggggacagtc ctgaaaaaga aaaagagttt gtaccgtgat
    63961 ctgacgggtg ttgttcagga agctgagaag cagtttatcc gagtcagtct gcgagaggag
    64021 cttcaattag atggacctga ttctgaaaga aatcagcgga tttttcaagc tttacgatat
    64081 tttgatttgg agcaggcagt cgataagagt ccctatcaat taagtggtgg tcagcaaaaa
    64141 attcttcagc tcctgaccat cttgaccagt aaggcttccg tgatcttgct agatgaacct
    64201 tttgcaggtt tggatgatag agcctgccat tatttttgca agtggattgt ggaggagagg
    64261 aaccaaggaa gaagttttct gctcattagt catcgtttag accctttgat ttctgtggtt
    64321 gattattgga ttgagatgac tagtcagggt cttcggcatg tgaaagaagt gaccattacc
    64381 aaaccactta catctcagag tagcaatacc caaggggagg tgagatagta tggtcaaagt
    64441 agcaacccag acaccgatta tcagtctctt cttgctgatt ttatccttgg aaacatcttt
    64501 cattccttcg attgctctga atctttcggt agtcgcattt tgtattctct ttatgctcta
    64561 ttaccgtcga tttaaaatgt tagcttggat gatcatactt gccattttac catcttttgc
    64621 caactactgg gcagttcagt tacacggaga tgcttcacag gcagtcatgc ttggaacgag
    64681 ggcttttgtg acagtttgta tcggccttgt ctttgtttcc tctatttcac taaaagagct
    64741 tctcttgtac ttggctcaaa aggggctatc acgctcttgg tcctatgcct tgattgtggt
    64801 attcaattcc tttcctctca ttcagcaaga aatcaagtcc ctcaaagaag cttgcctatt
    64861 acgtggtcaa gaactacatt tttggtcgcc cttgatttac agtaaggttc tgatgacagt
    64921 ctttaggtgg cgccatcttt acctgagagc tctatctgct cacggatatg acgaacatgc
    64981 acagttgaag aatagctatc ggacttttta tattcctaaa aaaacaaaat taatctacct
    65041 gcttttcttt ttattgcttc aaaccagtct atttttataa aggagttatt atggaattta
    65101 cagatattgc gatggaatta tccaagaaag cttggcaggc ttcctttcat catcccttta
    65161 ttttacaatt acaagagggg aatttagaac ctgccatttt ccgctattac ctgattcagg
    65221 atgcctacta tctgaaggct ttctcagaaa tctatcatct gttggctgat aagacttcaa
    65281 accaagagat gaaaagactc ttgaaacaaa atgctcaggg tttagtggag ggtgagttat
    65341 ttattcgcca acaatttttc aaggaattgg aaatcaacga ccaggaaatg gagcaacatc
    65401 caatcgctcc aacctgttat cattacattt ctcatattta taggcaattt gcagaaccga
    65461 acttagccat agcttttgca agcttgcttc cttgtccttg gttataccat gatataggca
    65521 aatcacttaa tcttaaacca tcaccaaatc ctctctatca acaatggatt gaaacttata
    65581 ttacggatga gttagagcaa cagatcagag aggagggagc actggtcaat cagctctatc
    65641 gagaaagtga tgagacagat aagcaaaaaa tgctagatgc cttccacatc agtgttcata
    65701 tggaagccaa gttttgggag atggcttacc aacaccagac atggaagagc gatttacagt
    65761 ctttagaaaa aggagaagaa tagaaacatg agaaagcacc aactacaagt tcacaaattg
    65821 accattttat ctatgatgat tgcccttgat gtagtcctta cacctatctt tcggattgag
    65881 ggaatggcac cgatgtccag tgtagtcaat attctagcgg gaatcatgat gggacctgtt
    65941 tatgccttgg ctatggctac agtgacagcc tttatccgta tgacgactca agggattccg
    66001 cctttagctc tcacaggagc gacttttgga gcccttctag caggtctctt ttataagtac
    66061 ggtcgaaaat tttacttttc tgccttggga gaaattgtgg gaacaggtat tattggttct
    66121 attgtttcct atcctgttat ggtactcttt acaggatcag ctgctaagct tagctggttt
    66181 atctacacgc ctcgattttt cggagcaacc ttgattggta cagcgatttc ctttattgcc
    66241 tttcgatttt taatcaagca ggaattcttt aaaaaagtgc agggatattt ctttagtgaa
    66301 aggatagact gatgcaggaa tttacaaatc cctttcctat aggctctagt tccctcattc
    66361 actgtatgac caatgagatt tcttgtgaga tgctggcaaa tgggattttg gctctgggat
    66421 gcaaacctgt catggcagat gattcccgtg aagttcttga ttttactaag caaagtcagg
    66481 ctctcttcat caatttaggt catttgtcag ctgagaagga gaaagcaatc cgcatggcag
    66541 cttcgtatgc aaaccaatct tctctcccga tggtagtaga tgcggttggc gtaacgactt
    66601 catccattcg taagagctta gttaaagacc ttttagacta tagacctacg gtccttaaag
    66661 gaaacatgtc agaaattcga agtcttgttg gattaaagca ccacggcgtt ggggtcgatg
    66721 cgagtgctaa agatcaagaa acggaggatt tgcttcaagt cttgaaagac tggtgtcaga
    66781 cctatcctgg tatgtcattc ttagttactg gccccaagga cctcatcgtt tcgaaaaatc
    66841 aggtcgctgt actggagaat ggctgtactg aattagactg gataacaggg acaggagatt
    66901 tggttggagc cttaacagcc gtttttctca gccaaggaaa gactggtttt gaagcttctt
    66961 gcttagcagt ctcttatctc aatatcgctg ctgagaaaat agttgttcaa ggaatgggat
    67021 tggaagaatt tcgttaccaa gtactcaatc agctttcgct cctaagaaga gatgaaaatt
    67081 ggctagatac catcaaagga gaggtttatg aatagagaag cacttagact atatctggta
    67141 accaatcgct atcaagattc cgtggaaagc tttcttgcaa aagttgagac ggcctgccgt
    67201 tcaggggtta ccatagtcca attgcgagaa aaaaatctca caaccaatca atattatcaa
    67261 ctggcaaaac aagtcaagga aataacagat gcttatcagg tacccttgat aatcgatgat
    67321 cggttggatg tttgtcttgc ggttgatgct gctggtctgc atattggaga tgacgaactc
    67381 ccagtttcgg ttgcccgaca agtcttgggt cctgaaaaaa tcctcggtgt caccgctaaa
    67441 acggttaaaa gagctctgga agcggagaaa tcaggtgcag attacttggg gacaggagcc
    67501 atttttccga caaccaccaa ggaaaatgca cccatcaccc tgatttcaac cttgaaaaca
    67561 atttgccaaa cggttgccat tccaatagtt gctattggcg gcttgacttc ggagaatatt
    67621 gatcagctta tgggcactgg catagctggt gtagctgttg tacgtgattt gatgcaagca
    67681 gaagatattg aggcaaaaac gcaagccttt ttaacaaagt tgcatgacat tctttcctaa
    67741 ttaatactca atgaaaatca aagagtaaac tagaaagcta gtcgcaggtt gctcaaagta
    67801 ctgccttgag gttttagata agactgacga agtcagctca aaacagtgtt ttgaagttgc
    67861 agatggaagc tgacgtagtt tgaagagatt ttcgaagagt ataaaaactc tctaattccc
    67921 ttaaagtggg aactagagag tttttttctt aatctttaaa agttgtatgg ttgactggac
    67981 cagaaccatg accgagttga ggggcatctt gaatagcttt tgtgataaag gccttggcct
    68041 tatcaactgc ctggtaaaga ctcttgccct tggctagttc agcagtaatc actgcagcaa
    68101 aggtacatcc agtaccatgg gtgtgacagg tttgaattcg tgggctttcc cagacaaatt
    68161 gttcattctt ggtaaagagg aaatctttag caccaccttt gagatgtccg cctttgagat
    68221 gtccgccttt gataaccaca gactgaggac caaattcttt taaaatcagg cgaccagcac
    68281 gctgcatgtc ttcggggtca tggattgaaa aaccaacaat ctcttctgct tcaggaagat
    68341 ttggcgtaat aatagttgct agaggtagta agtttgtttt gagatagtct ctagcatttg
    68401 agtcaatcaa ggcatctcca cttgtagcaa ccataacagg atcaaggaca tagggacaat
    68461 ccagtttttt aagatagggt tggatgattt ccatgatttc agtagtagcc aacattccag
    68521 tttttacagc ctgaggtgga atatcagaaa agacactctc caattgggct ttcaacattt
    68581 gaggagaaac gtgctcgatt agctgaacac ctctggtatt ttgagcgaca agactggtta
    68641 caacagccat tccatagaca tctctcgctt ggaatgactt taaatctgcc ataatgccag
    68701 caccaccact agggtcagtc cctgcaatgg tcaaagcaac gggtaaataa gtcatctaaa
    68761 acctcccaac caactgaagt ttgtattctt aagaacaagc tagtctgttt tagaaaggca
    68821 atagaagact gctagtcccc attatcattt ccacttccat cagctagtat tacctagatt
    68881 gagtcagagg gatctaacag tcgttaatct cagctttacg cacccctagt ggttgttttc
    68941 ttttttcttt agtatagcat atttttattg tttatatagt aatatttgac tgcaaatcgt
    69001 ttttcaaatg attaaaattc tatttttcga agaaaatatt atttctataa ttgacaaatg
    69061 tagattttaa gagtatactg atgagtgtaa ttgacaaatg tagattttgg aggtatggta
    69121 atgcagattt cagatgcaga atggcaggtc atgaagatta tttggatgca gggggagcag
    69181 accagtacag atttgattag ggttttggca gagcggttcg actggtccaa gtcaaccatt
    69241 caaactcttt tggctcgttt ggttgagaaa gagtgtctga ctcggaaaaa agaaggcaag
    69301 ttctttgttt attcagccct tttaactcta gaccaaagtc gggatttact tgtccaagat
    69361 atcaaagaca aggtttgttc ccgtaggatt aggaatttgt tggctgactt gattgtagaa
    69421 tgtgaattta ctcagactga cttggaagac ttggaagctg tgatttcaga gaagaaatca
    69481 agtgctgtaa cagaagtaag atgtaattgt atgtaaagga gacgtcatgt taaatagtat
    69541 tgtaaccatt atttgtattg cccttatcgc gtttatcttg ttttggtttt tcaaaaagcc
    69601 tgaaaaatct ggacaaaaag cccagcaaaa aaacggatac caagagattc gagtggaagt
    69661 catgggaggc tatactcctg agttgattgt cctcaagaaa tcagtgccag cccgcattgt
    69721 ctttgaccgc aaggatcctt caccatgtct ggatcaaatt gtttttccag attttggtgt
    69781 acatgcgaac ctgccaatgg gggaagagta tgtagtggaa atcacgcctg aacaggctgg
    69841 agagtttggc tttgcttgtg gtatgaacat gatgcacggc aagatgattg tagagtaggt
    69901 ggagactatg acagaaattg tgaaagcaag cttagaaaat ggcattcaaa aaatccgtat
    69961 ccgagctgaa aaaggctatc atccagccca tatccagctt caaaagggaa ttccagctga
    70021 gattaccttt catcgtgcta ctccttcaaa ctgttataag gaaattctgt ttgaagaaga
    70081 aggtatcttg gaaccaatcg gcgtagatga ggagaaagtc attcgtttta cacctcaaga
    70141 attagggcga catgaatttt cttgtggcat gaagatgcaa aagggaagct atatagtcgt
    70201 tgagaagact cgaaaatctc tatctctcct gcaacgtttt tggattacta gtatctttac
    70261 tgtgcctctt gtgattctca tgattgggat gttgacaggt agcattagtc atcaagtcat
    70321 gcattgggga acctttctag caacaacgcc tattatgtta gttgcaggta agccatatat
    70381 ccagagtgct tgggccagtt ttaaaaagca caatgccaac atggatacct tggttgcgct
    70441 gggaactcta gtggcttatt tctatagcct agttgctctc tttgctggtc tccctgttta
    70501 cttcgaaagt gctggattta tcctcttttt cgttcttttg ggagcagttt ttgaggaaaa
    70561 aatgagaaaa aatacgtccc aagctgtgga gaaattactg gacttgcaag ctaaaaccgc
    70621 agaagtcttg agtgatgata gttatgtcca agttcctttg gaacaagtca aggtaggcga
    70681 cctgattcga gtgcgtcccg gtgaaaagat tgctgttgat ggtgtcgtag tagaaggtgt
    70741 ctctagtatt gacgaatcca tggtgacagg tgagagtctg cctgtggaca agacagttgg
    70801 agatactgtc attggctcaa ccatcaatca tagtggaacg cttgtcttta gagcagaaaa
    70861 agttggctca gagactgttt tggctcagat tgtggatttt gtgaagaaag ctcagacaag
    70921 tcgtgcgccg attcaggact tgacggataa gatttcaggg atttttgtcc cagtagttgt
    70981 cattttagga atcatgacct tttgggtttg gttcgtcttg ctcagggata gtgtggtcgt
    71041 gcttggagct agctttgtgt cctctcttct ctacggagtg gcggttttga ttatcgcctg
    71101 tccttgtgcc ttgggacttg caacaccgac agcccttatg gtggggacag gacgtagtgc
    71161 caagatgggg gttctcctca aaaatggaac tgtcttacag gaaatccaga aagttcaaac
    71221 tcttgtcttt gataagaccg ggactttgac ggaagggaaa cctgtggtaa cagatatcat
    71281 cggcgacgaa gtagaagtgt ttggattggc agcctccttg gaagatgctt ctcaacaccc
    71341 actggctgag gctatcgtta agcgagcgag tgaagctgga cttgagtttc aaactgttga
    71401 aaattttcag gccttgcacg ggaaaggtgt ttcagggcga atcaatggaa aacaagtttt
    71461 acttggaaat gctaaaatgc tggatggcat ggatatttct aatacttatc aagataaact
    71521 agaagaacta gaaaaagaag ctaagacagt tgtgttttta gctgttgaca atgaaatcaa
    71581 aggcttgctt gctttgcaag atattcctaa ggaaaatgct aagctagcca tcagtcagct
    71641 aaaaaaacgt ggtctccgaa cagtcatgct gacaggagac aatgctggtg tggcgcgtgc
    71701 tattgcagat caaatcggaa ttgaagaggt cattgcaggc gtcttgccag aagaaaaagc
    71761 ccatgaaatc cataaactgc aacagtcagg taaagtagcc tttgttgggg acggtatcaa
    71821 tgacgctcct gcccttagtg tagcagatgt gggaattgct atgggtgctg gaacagatat
    71881 cgccatcgag tcagcagatt tggtgttgac aaccaataat cttttaggag tggttcgtgc
    71941 ctttgatatg agtaagaaaa cctttcatcg aattctactc aatcttttct gggcttttat
    72001 ctacaatgtt gtcggaattc cgattgcagc aggagtcttt tcaggtgttg gactggctct
    72061 caacccagaa ttggcaggtc tagccatggc ctttagttct gtatctgttc tgaccagttc
    72121 ccttctgtta aattttagta aaatagacta aaagtaatga ctagatttct ttgttataaa
    72181 acagaaacga caacactttc aaaactgtat tagaatagag aatagagagt tttgagcaga
    72241 tttttagaaa agtcagcata aatatgatac agtggaatag taaaaatttg gagaacgttt
    72301 ccaattctat gtaatcgtat tctccaagtt taaaaaaatt gaaggagagt tatcattatg
    72361 actcaaggga aaattactgc atctgcagca atgcttaacg tattgaaaac atggggcgta
    72421 gatacaatct acggtatccc atcaggaaca ctcagctcat tgatggacgc tttggctgaa
    72481 gacaaagata tccgcttctt acaagttcgc cacgaagaga caggtgctct tgcagcggtt
    72541 atgcaagcta aattcggcgg ctcaatcggg gttgcagttg gttcaggtgg tccaggtgcg
    72601 actcacttga ttaacggtgt ttacgatgca gctatggata acactccatt cctagcgatc
    72661 cttggatcac gtccagttaa cgaattgaac atggatgctt tccaagagct taaccaaaac
    72721 ccaatgtaca acggtatcgc tgtttacaac aaacgtgtag cttacgctga gcaattgcca
    72781 aaagtaattg acgaagcctg ccgtgctgca atttctaaaa aaggtccagc tgttgttgaa
    72841 attccagtaa acttcggttt ccaagaaatc gatgaaaact catactacgg ttcaggttca
    72901 tacgaacgct cattcatcgc tcctgctttg aacgaagttg aaatcgacaa agctgttgaa
    72961 atcttgaaca atgctgaacg cccagttatc tatgctggat ttggtggtgt taaagctggt
    73021 gaagtgatta ctgaattgtc acgtaaaatc aaagcaccaa tcatcacaac tggtaaaaac
    73081 tttgaagctt tcgaatggaa ctatgaaggt ttgacaggtt ctgcttaccg tgttggttgg
    73141 aaaccagcca acgaagtggt ctttgaagca gacacagttc ttttccttgg ttcaaacttc
    73201 ccatttgctg aagtttacga agcattcaag aacactgaaa aattcatcca agtcgatatc
    73261 gacccttaca aacttggtaa acgtcatgcc cttgacgctt caatccttgg tgatgctggt
    73321 caagcagcta aagctatcct tgacaaagta aacccagttg aatcaactcc atggtggcgt
    73381 gcaaacgtta agaacaacca aaactggcgt gattacatga acaaactcga aggtaaaact
    73441 gagggtgaat tgcaattgta tcaagtttac aatgcaatca acaaacatgc tgatcaagac
    73501 gctatctact caatcgacgt aggtaacact actcaaacat ctactcgtca ccttcacatg
    73561 acacctaaga acatgtggcg tacatctcca ctctttgcga caatgggtat tgcccttcct
    73621 ggtggtatcg ctgctaagaa agacaatcca gatcgccaag tatggaacat catgggtgac
    73681 ggagcattca acatgtgcta cccagacgtt atcacaaacg ttcaatacga ccttccagtt
    73741 atcaaccttg tcttctcaaa tgctgagtac ggcttcatca agaacaaata cgaagataca
    73801 aacaaacact tgtttggtgt agacttcaca aacgctgact acgctaaaat tgcggaagct
    73861 caaggagctg ttggattcac agttgaccgt atcgaagaca tcgatgcagt tgttgcagaa
    73921 gctgttaaat tgaacaaaga aggtaaaact gttgtcatcg atgctcgcat cactcaacac
    73981 cgtccacttc cagtagaagt acttgaattg gatccaaaac ttcactcaga agaagctatc
    74041 aaagccttca aggaaaaata cgaagcagaa gaactcgtac cattccgtct cttcttggaa
    74101 gaagaaggat tgcaatcacg cgcaattaaa taattcctct cgccgaaaat caaatatgaa
    74161 acttgtagac tttattcttt gattttcata gagcagaact ttaaaagatc ggagcaatcc
    74221 ggtcttttta tggaggagag taaatgaatt taaatcaatt agatattatc gtttcaaatg
    74281 ttccccaagt ctgtgctgac ttggagcata ttttggataa aaaggcagat tatgctgatg
    74341 atggttttgc tcagtttacg attggtagtc actgccttat gttgtcacaa aatcatttgg
    74401 ttcctttgga aaactttcag tcaggaatca ttattcatat cgaggttgag gatgtagacc
    74461 agaactacaa acggttgaac gagcttggta taaaggtttt acacggacca actgtaaccg
    74521 attggggaac agagtcctta ttagttcaag gacctgctgg tctagtgctt gatttttatc
    74581 gtatgaaata ggtcgcgtag tcatttgacg ttaaccttag ctatttttaa aatagaaatt
    74641 gagaatatga actattgaaa gatcggagca atccggtctt tttatataaa gaaattgcat
    74701 ataatactca tctgctttca aaaagcattc tagtccatct ccgattaacg atggacttta
    74761 tcacctcctt ctccagtcct tgtatgacat cttggagttg attcatgaca tcttccaaag
    74821 ttcgaaaggc tttattctta aatccacgtt tacgaatctc tttccacact tgttcaatgg
    74881 ggttcatctc tggtgtgtat ggaggaataa atgcaaagcc aatattagtc ggaatcttta
    74941 aggtacttga tttatgccat atagcattgt ctataacgag taaaaaataa tcatatggat
    75001 aagcttgtga aagctcttct aaaaaggcgt tcatccactc agtattacat ctaccagcta
    75061 ttaagaaaaa tgattcgcct gtatgggcat caacagctcc ataacaatag cgaaattctc
    75121 gtatatagtg actatggaca tgtggaccta ctcctattgg agaccaacaa gatcccagtt
    75181 tactgattct accgaaacca gcttcatctt ggtacatcaa gcgaacctta tgaaaaggtc
    75241 tactggtttt aaaacgcttt cttgtcttct tgaattgaga ctttattttt agacgcgaca
    75301 atggtttgag cgtctgcttt cctaggatgt tctggacgtg gcgtaatatt tcgccaacca
    75361 tggcgcttca acagttgata gaaggcatca cgtgtgtagg aacgacctaa ctccttttta
    75421 taagcctgaa ataaggcatc aattgtaaca aattctcctg cctctgtagc cttcaaatgg
    75481 cgggcaagaa agactttctc ttgctcaacc gtcatataag catggttacg accaccacgt
    75541 gtttcttgaa ggagagagtc gagtccgaac tcctcatatt ttttacattt cgccaaatcg
    75601 ttgtttgatt acagtctaaa gtgtattgaa tctataacag tacaccttgg ctgctaaaat
    75661 atttctataa atta
//
LOCUS       DAVDHC010000009        72243 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVDHC010000009 DAVDHC010000000
VERSION     DAVDHC010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 72243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72243
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.009"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            101..2230
                     /locus_tag="VUR43_000803"
     CDS             101..2230
                     /locus_tag="VUR43_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET5412517.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNVYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            2217..2666
                     /locus_tag="VUR43_000804"
     CDS             2217..2666
                     /locus_tag="VUR43_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET5412518.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            2725..2997
                     /locus_tag="VUR43_000805"
     CDS             2725..2997
                     /locus_tag="VUR43_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET5412519.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(3351..3542)
                     /locus_tag="VUR43_000806"
     CDS             complement(3351..3542)
                     /locus_tag="VUR43_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412520.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNILSQQQK"
     gene            3970..4728
                     /locus_tag="VUR43_000807"
     CDS             3970..4728
                     /locus_tag="VUR43_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412521.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            4730..6718
                     /locus_tag="VUR43_000808"
     CDS             4730..6718
                     /locus_tag="VUR43_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5412522.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTELTIFEKGQNRVQPKTIFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKTLILNDHQFSVKEEFNKDFIVKHVPNQF
                     NILTADYNYLVVPDLQAFLNQFPDSAIYNQFYGGMNVNVSEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(6760..7404)
                     /locus_tag="VUR43_000809"
     CDS             complement(6760..7404)
                     /locus_tag="VUR43_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET5412523.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(7376..8425)
                     /locus_tag="VUR43_000810"
                     /pseudo
     CDS             complement(7376..8425)
                     /locus_tag="VUR43_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            9132..10607
                     /locus_tag="VUR43_000811"
     CDS             9132..10607
                     /locus_tag="VUR43_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET5412524.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(10573..11288)
                     /locus_tag="VUR43_000812"
                     /pseudo
     CDS             complement(10573..11288)
                     /locus_tag="VUR43_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            11544..12404
                     /gene="speE"
                     /locus_tag="VUR43_000813"
     CDS             11544..12404
                     /gene="speE"
                     /locus_tag="VUR43_000813"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET5412525.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            12401..13660
                     /locus_tag="VUR43_000814"
     CDS             12401..13660
                     /locus_tag="VUR43_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET5412526.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            13660..14787
                     /gene="nspC"
                     /locus_tag="VUR43_000815"
     CDS             13660..14787
                     /gene="nspC"
                     /locus_tag="VUR43_000815"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET5412527.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            14784..15869
                     /gene="aguA"
                     /locus_tag="VUR43_000816"
     CDS             14784..15869
                     /gene="aguA"
                     /locus_tag="VUR43_000816"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET5412528.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            15879..16754
                     /gene="aguB"
                     /locus_tag="VUR43_000817"
     CDS             15879..16754
                     /gene="aguB"
                     /locus_tag="VUR43_000817"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET5412529.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(16934..17743)
                     /locus_tag="VUR43_000818"
     CDS             complement(16934..17743)
                     /locus_tag="VUR43_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET5412530.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            18015..18236
                     /locus_tag="VUR43_000819"
     CDS             18015..18236
                     /locus_tag="VUR43_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412531.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLVYIVGGNHLCKGSAARF"
     gene            18290..18961
                     /locus_tag="VUR43_000820"
     CDS             18290..18961
                     /locus_tag="VUR43_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5412532.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLLESGVLLSAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(19013..19210)
                     /locus_tag="VUR43_000821"
     CDS             complement(19013..19210)
                     /locus_tag="VUR43_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412533.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            19203..20111
                     /locus_tag="VUR43_000822"
     CDS             19203..20111
                     /locus_tag="VUR43_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET5412534.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            20108..20569
                     /locus_tag="VUR43_000823"
     CDS             20108..20569
                     /locus_tag="VUR43_000823"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET5412535.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            20559..21446
                     /locus_tag="VUR43_000824"
     CDS             20559..21446
                     /locus_tag="VUR43_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET5412536.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            21449..23360
                     /gene="cbpE"
                     /locus_tag="VUR43_000825"
                     /gene_synonym="pce"
                     /pseudo
     CDS             21449..23360
                     /gene="cbpE"
                     /locus_tag="VUR43_000825"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
     gene            23440..24570
                     /locus_tag="VUR43_000826"
     CDS             23440..24570
                     /locus_tag="VUR43_000826"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET5412537.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            24580..25842
                     /locus_tag="VUR43_000827"
     CDS             24580..25842
                     /locus_tag="VUR43_000827"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET5412538.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            25846..26643
                     /gene="proC"
                     /locus_tag="VUR43_000828"
     CDS             25846..26643
                     /gene="proC"
                     /locus_tag="VUR43_000828"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET5412539.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLILEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            26863..27501
                     /locus_tag="VUR43_000829"
     CDS             26863..27501
                     /locus_tag="VUR43_000829"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET5412540.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEVKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            27498..28388
                     /locus_tag="VUR43_000830"
     CDS             27498..28388
                     /locus_tag="VUR43_000830"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET5412541.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            28428..28745
                     /gene="yabA"
                     /locus_tag="VUR43_000831"
     CDS             28428..28745
                     /gene="yabA"
                     /locus_tag="VUR43_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET5412542.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            28748..29626
                     /gene="rsmI"
                     /locus_tag="VUR43_000832"
     CDS             28748..29626
                     /gene="rsmI"
                     /locus_tag="VUR43_000832"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET5412543.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEENQEND"
     gene            29761..31095
                     /gene="trmFO"
                     /locus_tag="VUR43_000833"
     CDS             29761..31095
                     /gene="trmFO"
                     /locus_tag="VUR43_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET5412544.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            31179..31916
                     /locus_tag="VUR43_000834"
     CDS             31179..31916
                     /locus_tag="VUR43_000834"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET5412545.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            31925..32482
                     /gene="frr"
                     /locus_tag="VUR43_000835"
     CDS             31925..32482
                     /gene="frr"
                     /locus_tag="VUR43_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET5412546.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            32542..33396
                     /gene="cvfB"
                     /locus_tag="VUR43_000836"
     CDS             32542..33396
                     /gene="cvfB"
                     /locus_tag="VUR43_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET5412547.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            33405..33620
                     /locus_tag="VUR43_000837"
     CDS             33405..33620
                     /locus_tag="VUR43_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET5412548.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            33706..34710
                     /locus_tag="VUR43_000838"
     CDS             33706..34710
                     /locus_tag="VUR43_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET5412549.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIYQIDFVHFSAKDVVRHPVVAQIIRAYEPAPVKKEESEELESQPLSEG
                     "
     gene            34818..35387
                     /locus_tag="VUR43_000839"
     CDS             34818..35387
                     /locus_tag="VUR43_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412550.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKDRIVTRVHYVLTKEDYFANK"
     gene            35455..36105
                     /locus_tag="VUR43_000840"
     CDS             35455..36105
                     /locus_tag="VUR43_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HET5412551.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            36089..38329
                     /locus_tag="VUR43_000841"
     CDS             36089..38329
                     /locus_tag="VUR43_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET5412552.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            38508..38696
                     /locus_tag="VUR43_000842"
     CDS             38508..38696
                     /locus_tag="VUR43_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412553.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGSY"
     gene            38728..39315
                     /locus_tag="VUR43_000843"
     CDS             38728..39315
                     /locus_tag="VUR43_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412554.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            39319..40500
                     /locus_tag="VUR43_000844"
     CDS             39319..40500
                     /locus_tag="VUR43_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412555.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKIEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    40660..40791
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            40807..41337
                     /gene="infC"
                     /locus_tag="VUR43_000845"
     CDS             40807..41337
                     /gene="infC"
                     /locus_tag="VUR43_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET5412556.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            41370..41570
                     /gene="rpmI"
                     /locus_tag="VUR43_000846"
     CDS             41370..41570
                     /gene="rpmI"
                     /locus_tag="VUR43_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET5412557.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            41622..41981
                     /gene="rplT"
                     /locus_tag="VUR43_000847"
     CDS             41622..41981
                     /gene="rplT"
                     /locus_tag="VUR43_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET5412558.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            42039..42419
                     /locus_tag="VUR43_000848"
     CDS             42039..42419
                     /locus_tag="VUR43_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5412559.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            42669..43469
                     /locus_tag="VUR43_000849"
     CDS             42669..43469
                     /locus_tag="VUR43_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET5412560.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPENETVSQRVCEDGPVFRTGTVVL"
     gene            43480..44418
                     /locus_tag="VUR43_000850"
     CDS             43480..44418
                     /locus_tag="VUR43_000850"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET5412561.1"
                     /translation="MTTNRLQVSLPGLDLKNPIIPASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            44460..46493
                     /locus_tag="VUR43_000851"
     CDS             44460..46493
                     /locus_tag="VUR43_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET5412562.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGVKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSTDGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(46554..48209)
                     /gene="pavA"
                     /locus_tag="VUR43_000852"
     CDS             complement(46554..48209)
                     /gene="pavA"
                     /locus_tag="VUR43_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET5412563.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQAGEPFANLSDLLDTYYKNKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            48314..48811
                     /gene="ybeY"
                     /locus_tag="VUR43_000853"
     CDS             48314..48811
                     /gene="ybeY"
                     /locus_tag="VUR43_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET5412564.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            48792..49187
                     /locus_tag="VUR43_000854"
     CDS             48792..49187
                     /locus_tag="VUR43_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET5412565.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENMVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            49204..50103
                     /gene="era"
                     /locus_tag="VUR43_000855"
     CDS             49204..50103
                     /gene="era"
                     /locus_tag="VUR43_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET5412566.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            50152..50976
                     /gene="mutM"
                     /locus_tag="VUR43_000856"
     CDS             50152..50976
                     /gene="mutM"
                     /locus_tag="VUR43_000856"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET5412567.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            50976..51581
                     /locus_tag="VUR43_000857"
     CDS             50976..51581
                     /locus_tag="VUR43_000857"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET5412568.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELVTLREQ
                     LAQTEEIFFMDIPLLFEQDYSAWFTETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            51568..52767
                     /locus_tag="VUR43_000858"
     CDS             51568..52767
                     /locus_tag="VUR43_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET5412569.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGFYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            52767..52916
                     /gene="rpmG"
                     /locus_tag="VUR43_000859"
     CDS             52767..52916
                     /gene="rpmG"
                     /locus_tag="VUR43_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET5412570.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            52956..53189
                     /gene="secG"
                     /locus_tag="VUR43_000860"
     CDS             52956..53189
                     /gene="secG"
                     /locus_tag="VUR43_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET5412571.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            53291..55645
                     /gene="rnr"
                     /locus_tag="VUR43_000861"
     CDS             53291..55645
                     /gene="rnr"
                     /locus_tag="VUR43_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET5412572.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERIIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            55608..56075
                     /gene="smpB"
                     /locus_tag="VUR43_000862"
     CDS             55608..56075
                     /gene="smpB"
                     /locus_tag="VUR43_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET5412573.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            56091..56951
                     /gene="tehB"
                     /locus_tag="VUR43_000863"
     CDS             56091..56951
                     /gene="tehB"
                     /locus_tag="VUR43_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET5412574.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            57024..57977
                     /gene="coiA"
                     /locus_tag="VUR43_000864"
     CDS             57024..57977
                     /gene="coiA"
                     /locus_tag="VUR43_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET5412575.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQYFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            57996..59798
                     /gene="pepF"
                     /locus_tag="VUR43_000865"
     CDS             57996..59798
                     /gene="pepF"
                     /locus_tag="VUR43_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET5412576.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLYRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKIGLA"
     gene            59800..60513
                     /locus_tag="VUR43_000866"
     CDS             59800..60513
                     /locus_tag="VUR43_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET5412577.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGSLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            60580..61521
                     /gene="prsA"
                     /locus_tag="VUR43_000867"
     CDS             60580..61521
                     /gene="prsA"
                     /locus_tag="VUR43_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET5412578.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(61640..61969)
                     /locus_tag="VUR43_000868"
                     /pseudo
     CDS             complement(61640..61969)
                     /locus_tag="VUR43_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            62392..62487
                     /locus_tag="VUR43_000869"
                     /pseudo
     CDS             62392..62487
                     /locus_tag="VUR43_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(62740..63360)
                     /locus_tag="VUR43_000870"
     CDS             complement(62740..63360)
                     /locus_tag="VUR43_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET5412579.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPGSIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(63360..63842)
                     /locus_tag="VUR43_000871"
     CDS             complement(63360..63842)
                     /locus_tag="VUR43_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET5412580.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYHIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(63842..64684)
                     /locus_tag="VUR43_000872"
     CDS             complement(63842..64684)
                     /locus_tag="VUR43_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET5412581.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(64779..65579)
                     /locus_tag="VUR43_000873"
     CDS             complement(64779..65579)
                     /locus_tag="VUR43_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET5412582.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSAQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            65723..67102
                     /gene="glmU"
                     /locus_tag="VUR43_000874"
     CDS             65723..67102
                     /gene="glmU"
                     /locus_tag="VUR43_000874"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET5412583.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            67112..67657
                     /locus_tag="VUR43_000875"
     CDS             67112..67657
                     /locus_tag="VUR43_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5412584.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELKKK"
     gene            67669..67983
                     /locus_tag="VUR43_000876"
     CDS             67669..67983
                     /locus_tag="VUR43_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET5412585.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            68000..68692
                     /locus_tag="VUR43_000877"
     CDS             68000..68692
                     /locus_tag="VUR43_000877"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET5412586.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVCGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            68769..69260
                     /gene="rocS"
                     /locus_tag="VUR43_000878"
     CDS             68769..69260
                     /gene="rocS"
                     /locus_tag="VUR43_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET5412587.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            69358..69948
                     /locus_tag="VUR43_000879"
     CDS             69358..69948
                     /locus_tag="VUR43_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET5412588.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNATKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            69957..71720
                     /locus_tag="VUR43_000880"
     CDS             69957..71720
                     /locus_tag="VUR43_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET5412589.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLLPLLLAQTLVDDITQRESLVLGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            71934..72243
                     /locus_tag="VUR43_000881"
                     /pseudo
     CDS             71934..72243
                     /locus_tag="VUR43_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT        21647 a        13316 c        16124 g        21156 t
ORIGIN      
        1 ttttgagcag cctgcggcta gcttcctagt ttgctttttg attttcattg agtatgaaaa
       61 ggattggaga aagccttcca gcttgtggta taatagattt atggataaaa aatatgaaaa
      121 aatctctcag gatttgggag tgacgttaaa gcaaattgat accgttctaa gtttgacagc
      181 tgaaggggcg actattccct ttatcgcgcg ttatcgcaag gacatgactg gtagtctgga
      241 tgaggtggcg attaaggcta ttattgattt ggataaaagt ctgacaaatc tcaatgaccg
      301 taaggaagct gtcttagcta agattcaaga acaaggtaag ttgaccaagg aattggaaga
      361 agctatctta gttgccgaaa aattagcaga cgttgaagaa ctctatcttc cttataagga
      421 aaagcgtcgt accaaggcaa ccattgcccg tgaagctgga ctctttcctc ttgctcgctt
      481 gattttgcag aatatagttg acttagagaa agaagctgaa aagttcgtct gtgaaggatt
      541 tgcgactggc aaggaagcct tgaccggtgc agttgatatt ttggtcgaag ccttatcgga
      601 agatgtgacc ttgcgttcta tgacttatca ggaagtgctg agacactcta aacttacttc
      661 tcaagccaag gatgaaagtc ttgatgaaaa gcaggttttt cagatttatt atgatttttc
      721 agagacagtt ggaactatgc aaggctatcg taccttggct ctcaatcgtg gggagaaact
      781 tggtgtcttg aagatcggtt ttgaacatgc gacggaccgt attcttgcct tctttgctac
      841 tcgtttcaag gtgaaaaatg tttatattga tgaagttgtt cagcaatccg ttaagaaaaa
      901 ggtcttgcct gctatcgagc gtcgtattcg gacagaatta actgagaaag ctgaagaagg
      961 agctatccaa cttttttctg acaatctgcg caatctcctc ttggttgctc cactgaaagg
     1021 gcgcgtggtt cttggatttg acccagcctt tcgtacaggt gccaagttag ctgtcgtgga
     1081 tgcaacagga aaaatgctga caactcaggt tatttatcct gttaaaccag catcagctcg
     1141 tcaaatcgaa gaagccaaga aagatttagc agatttaatt ggtcaatacg gtgtagagat
     1201 tattgccatt ggaaatggaa cggccagtcg tgaaagtgaa gcttttgtag cggaagttct
     1261 gaaagatttc cctgaagtca gctatgttat cgttaatgaa agtggtgctt ctgtctattc
     1321 tgccagcgaa cttgctcgtc aggagtttcc agacttgacc gttgaaaaac gttctgccat
     1381 ttctatcgcc cgtcgtttgc aagatcctct tgcggaattg gtcaaaatcg atcctaagtc
     1441 aattggtgtc ggtcaatacc aacacgatgt cagtcagaag aaactatctg agagtctgga
     1501 ctttgttgtc gatacagtgg ttaaccaagt tggtgtcaat gtcaatacag ctagcccagc
     1561 tcttctttca cacgtagctg gactcaacaa aactatctct gaaaatattg tcaaataccg
     1621 cgaggaagaa ggaaaaatca cttcacgcgc ccaaatcaag aaagttcctc gtctgggagc
     1681 caaggccttt gagcaggctg ctggtttcct tcgtatccct gaaagtagca atatccttga
     1741 taatacagga gttcacccag agaattacac tgcagttaag gaactcttca aacgtttaga
     1801 tattaaagac ctaaacgaag aagcccaaag caaactcaag tccctttcag tcaaggaaat
     1861 ggctcaagag ctagacctcg gtccagaaac ccttaaagat atcattgcag atcttctcaa
     1921 accaggtcga gatttccgtg attcctttga cgcacctgtg cttcgccaag atgtcctaga
     1981 tatcaaagac ctagtggtag gtcagaagct agaaggtgtt gtgcgtaacg ttgttgactt
     2041 cggtgccttc gttgatatcg ggattcacga ggacggcttg attcatattt ctcatatgag
     2101 tcgcaagttt atcaaacacc ctagtcaagt ggtgtcagtt ggagatttgg tgaccgtttg
     2161 ggtcaagaaa attgatactg aacgtgaaaa agttaatctg tcgctcctcg ctccaaatga
     2221 aactgactga ttatgtcaag caggtttcac tagaagactt cgggagagct tttatccatc
     2281 atgtccagtg gaataggcgt ctacgttcga caggtgggcg atttttcccc aaagatgggc
     2341 atctggattt taatcccaag gtttatcaga aactgggtat ggaggttttt aggaaaattg
     2401 tccgacatga actctgtcat tatcaccttt atttccaagg gaagggctat caacacaagg
     2461 atcgggattt taaggaactt ttgaaagcag tggatggatt acggtttgta ccatccttgc
     2521 ccaatagtaa ctctaaacca ctcaagcttt atcgttgtca atcctgccag caaaggtatc
     2581 agcgcaagcg taggattgat accaaacgct atcgctgtgg actttgtcga ggtaaattgc
     2641 ttctgataaa tcagcctgag gactgatgaa agccgagcct ccccgtgata tactatgtct
     2701 aacctagcag aaagaggaaa tatcatgaac agtaaatttt ataaaatgag acgcaatcgc
     2761 atgatttcag gagttctggc aggtctgtca gacaagtgga attttgatgt taccctagtt
     2821 cgtttcttgt ttgctatttt tacagttgca aactttggac ttggcgtgat tatctatatc
     2881 atcctagctt ctatcatgcc taccaaggaa gaaatcgaag cagaaatgta cggaacaggc
     2941 ccacgtaaac gcaaagaagc ccaagccatt gacgacaatg aaggctggtt ttggtgaggt
     3001 tctacagaag atttggaata agcaaaaagc tttaaatcaa tagtctaaac tgcttgattt
     3061 aaagcttttt tacttttata ctcaataaaa atcaaagtgc aaactaggaa gccagccaca
     3121 ggctgtaatt tagtcggcaa tgtgaagttg acatagtttg cactttgatt tttgaatagt
     3181 attaataata tttcgccagc ttcatccaca aactatagtg gattggaact agaatagtac
     3241 acctctactt ctaaaacatt gttagaaatc gatttgacta tcctgatcga tttgtcctgt
     3301 tcttatttca ttttattata aaagcagtaa tttaaacgca gttttttaat ctatttttgc
     3361 tgctgagaca atatattttt ggaaaaatgg tggatgctga taacaactga taaccagcaa
     3421 ataacataag cagtgccggt aaattctgta ccgataaagt gtgtgtgttc aactaagagc
     3481 tgaccgatga atggagagag cagatagaga agtccgatga gtatatgttc tttgtgtttc
     3541 attaaagcgc accttctttc cttataggtt gaacgacttg caagtgttaa attgaatggt
     3601 atgttatcta ggtaacctta ctaaaatgtt agttcccgct tcctcctttt caaagtaagc
     3661 cttttcacac ttatatttta caactttaaa aataggaaat caaatcattt tctaagtaat
     3721 tttgcttata tttcacccaa tcttacaaaa atgtaagatt aaagtctctt ttgtaaggtt
     3781 aggttatggc aagcggtctt tttttgatgt aaactagact cataaagaac aaaggagtaa
     3841 catcatgaaa caaatcttac ataagaaaac tagaaaacca agtcacaaag aaattgagcg
     3901 cgttcagctg ggatgcacta tgatgcaagc tacatttcat ttgatgggat attaagaaag
     3961 gagattctca tgacactttt agatgtaaaa cacgttcaaa aaatttataa aacacgtttt
     4021 cagggcaacc aagtagaagc cctcaaggat attcacttta ccgtcgaaaa gggtgactac
     4081 gttgccatca tgggtgagtc tggttctggt aaatcaactc ttctcaatat tctagctatg
     4141 ctggataaac caagtcgtgg tcaggtttac ttgaatggaa ctgacaccgc aaccattaaa
     4201 aattcacagg cctctagctt ccgtcgtgaa aagttgggct ttgtcttcca agactttaac
     4261 ttgctagata ctctatctgt aaaggacaat atcttgcttc cgcttgtctt gtcaagaaga
     4321 cctattacag agatgatgaa gaaattggtg gtgacagctg agaatctggg aataaaccaa
     4381 ttacaagaga agtaccctta cgagatttct ggtggtcaga aacagcgtgt agcagtagcc
     4441 cgcgccatca tcacagaacc tgaaattctc cttgcggacg aaccgacagg agctcttgac
     4501 tccaagtcat ctgcagcctt acttgatgtc tttgatgaaa tcaatgagcg cggccaaacc
     4561 attctcatgg taacccactc aacagcagca gctagcagag ctaaacgtgt actctttatc
     4621 aaagacggca ttctttacaa tcaaatctac cgtggagaga agacagaacg tcagatgttc
     4681 caagaaatct ctgatacctt gactgtcatg gcaagcgagg tgaattagta tgtttcgatt
     4741 aaccaataag ttagcggtat cgaacttgat taaaaaccgc aaactctact atccttttgc
     4801 gctggctgtt ctcttggcag tcactgtcac ctatctcttt tactctctaa ccttcaatcc
     4861 taagattgcg gaaatccgtg gaggaacaac cattcaggct acacttggat ttggtatgtt
     4921 tgtcgtcacc cttgcgtcag ccattatcgt tctctatgcc aatagttttg tcatgaagaa
     4981 ccgttccaag gaactaggaa tttatggcat gttgggcttg gagaagcgtc atcttatcag
     5041 tatgaccttt aaggagttag tggtatttgg gattctaact gttggagcgg gtatcggtat
     5101 tggagccttg tttgacaagt taattttcgc tttcctgctc aaactaatga aattgaaggt
     5161 tgagctggtt gctaccttcc agacgaaagt tgtcattaca gtgcttgttg tcttcggttt
     5221 gattttccta ggcctcatgt tcctgaatgc ccttcgaatc gcccgtatga atgccctcca
     5281 gctctctcgt gagaaagcta gtggagagaa aaaaggtcgc ttccttcctc tccaaaccat
     5341 tcttggttcc ataagtttag gaattggcta ttatcttgcc cttacggtaa aagatcctct
     5401 tacagcctta acaaccttct tcatagctgt tttactggtt atctttggga cttatctctt
     5461 gtttaatgca gggattaccg ttttcctcca aatcttaaag aaaaataaga aatactatta
     5521 ccaaccaaat aacctcatat ctgtttctaa cttgattttc cgtatgaaga aaaatgcagt
     5581 tggactagcc accatcgcta tcttgtcaac aatggttttg gtaaccatgt cagcagcgac
     5641 aagcattttc aattcctcag aaagctttaa aaaagttcta aatcctcatg attttggggt
     5701 ttcagggcaa aatgttgaaa aagaagactt ggacaaactc ttgagccagt ttgcaagtga
     5761 caaaggttat aagattaaag aaaaagaagt atttcgttac acttactttg ctgttgcgaa
     5821 tcaagaagga accgagttaa ctatttttga aaaaggacaa aaccgtgtcc aaccaaaaac
     5881 aattttcatg gtatttgacc aaaaagatta tgaaaatatg actggtcaaa aactgtctct
     5941 atcaggaaat gaggtcggac tctttgcaaa gaatgaggga gttaaagaac agaaaactct
     6001 aattctgaat gatcatcaat tttctgtaaa agaagaattt aataaagatt ttattgtcaa
     6061 gcatgtccca aatcagttta atattttgac tgctgattac aattaccttg ttgtacctga
     6121 tttacaagcc tttttgaacc aattcccaga ttcggctatc tataatcagt tttacggtgg
     6181 tatgaatgta aatgtcagtg aagaagagca actcaaagtc gctgaagaat atgaaaaata
     6241 cttacaaaag tttaatgctc aattaaacac tgaaggtaac tatgtgtatg gtagcactct
     6301 agcagatgct agtgctcaaa tgagtgtcct ctttggcggt gtcttcttta tcggtatttt
     6361 cctatccatt atctttatgg tcggaaccgt tctggtcatc tactacaaac aaatttctga
     6421 aggctacgaa gaccgtgagc gctttattat cttgcagaaa gtcggtttag atcaaaagca
     6481 aatcaagcaa accatcaaca aacaggtttt aactgtattc ttccttcctt tgctctttgc
     6541 cttcctacat ctagcctttg cctaccatat gcttagtctg attttaaaag tgattggtgt
     6601 actggatacg actatgatgt tgattgtgac cttgtctatc tgcgctatct tcctcatcgc
     6661 ctatgtgctg attttcatga ttacttcaag aagttatcgc aagattgtgc aaatgtaaaa
     6721 aagatacctc gacttcaaaa tcgaggtatt tcttgttttc taaatgctga aaagttgtcc
     6781 gagcaggaag gtaactccca tagttaagag accaatagca aggttccgaa tcatagctgt
     6841 tttggttggg gcttttccaa gtctagcgct tgtgtagcca gtgagaagaa gggctacacc
     6901 gacgataagg acggtagcag ggatgcggta atcacttgga aaaatggtca ctgacagcat
     6961 tggaggcaaa cttctaagga aaaaggcaac gaagctagaa atggcagcgt gccaaggatt
     7021 ggtaaattct tcatactcaa tcccatattt ttcctctacc agagccttga gtggattttt
     7081 aagaaagatc ttattggtca agagttgggc agaagttttg cattctccat tttggatata
     7141 agcagcatag agggattttt tggctagttc cctatcttgg tctaacaaga gtttttctcg
     7201 cgaaacggca gcttcctcgg tatcttttgg agttgaaacg gatacatatt ctccaccagc
     7261 cattgaaaag gcaccagcta agatagccgc aaatcctgat aaaaagataa tccagatatt
     7321 ggtcgtggca ctggcaaccc cgataaccac accagcaatg gaaataattc catcgttagc
     7381 accaagaaca cctgcgcgca ggatatttaa acgacctgca aaatttgaat cgatttcgtg
     7441 atttgtttct gacgctaaat ttcaagttca agttagccat ccagaagtct tctctgggtg
     7501 acttgtagtc caagcatttt ttaggatagt tgttaatcca cttttcgatg aatgcgactt
     7561 ccttaggagt cattttcttg gttcccttag gtaaccatct acgaatgaac ctgttgtgat
     7621 tctcattagt tcccctttcc caagaggcat aggggtgcgc ataataaatg tgctcctcag
     7681 aaaatacatc agacaagcga ttgaattccg ttccattatc tgccgtgatg gaaagaatct
     7741 tgtgttgttt taagatgagt tttagagcct gattgaccac ctcagcactt ttatttggaa
     7801 tcaatcggat gatctgatgt ctactctttc gatccgtcaa gacaagcaag cagtagtttt
     7861 tcgatctcgt aagtagaacc gtatcaatct cataatgccc attctccaag cgaagattga
     7921 tagcttcagg ccgctgtgcg atggattgac cagcaggttt aaagttggtg ctagcctgtt
     7981 tcttaagcac ttttcctttt ctagggtaaa gcagatcctg cttgcttaac cccaattttc
     8041 catgatgaat ccaatagtaa atggttgaaa ttcccacgtt aaccccttta gccatcacca
     8101 tcatttcagg cgaaaatttt tggttatgat agtggagaat cttttccttt agttcctttg
     8161 tcaagcttga tttcttgacc gagcgcttgc gattgttttc ataagactgt tgagcatagt
     8221 cggcagaata aacctctttg aagcgccctt ttccaagaca ttgtcggact gtcccacgct
     8281 tgatttcagt gtggatagtt taaggagctt ttccaagtag agaggcaatt tctctatttg
     8341 atttcccttc ttttttccat ctttcgatta agcgacggct atcgattgtc aaatgtttgg
     8401 cttttgtagt ataattttct tgcatctctg tgcctttctt gtgtttgtgg ttgaacaaca
     8461 agtataacac agaggtgttt tcttatgcct acaagagcta tcagctagtt gaaccatcta
     8521 atttttagga gggctgggtg gctaacttca ttatagaact ttcatttacg aacatatagt
     8581 aaaatgaaac aagaacagaa caaatcgatc aggacagtaa aatctatttc taataatgtt
     8641 ttagaagcag aagtgtacta ttctagtttc aatctattat atttttgttt tttatcaaaa
     8701 aatactttac aagttcttaa aaacatgata tagtaataaa gcttagaaaa tgagatgatg
     8761 ttttctagca aatataaacc cgagtaaaaa atgcctacgg acaggcaggg ttgaatgccg
     8821 aagcgtggtt gaaaagccac attattgata gggttaaaag cctactttta taagttgatg
     8881 ttaggacact tgtcctaatt cataaatttt tagtgtggtg aaagcacacg tcatcttgtg
     8941 aaacgatcaa taaagtacgt aatatttgct actagagagt taggaaacat cgggaacaga
     9001 catactcaac agaaaccaaa ataaacacgt cagaagattg cagagcaggt gaaaacctgc
     9061 tcttttttca tgagtcaacc tttagttcct tagttttcat aaggtcctaa aaatattgaa
     9121 aggagtatgt tttgaaagag ttagatcaaa accaagcccc aatttatgag gccttggtga
     9181 agttacgcaa gaaaaggatt gttccctttg atgttccagg tcacaagcgt ggacggggaa
     9241 atccagaact tgtcgaactc ttaggagaaa aatgtgtagg cattgatgtc aattcgatga
     9301 aacccttgga taatttaggc catcctattt cgattattcg tgatgcagag gagctggctg
     9361 cagatgcttt tggagctagc catgcctttc taatgattgg tggaacaact tcatcggtgc
     9421 agactatgat tctggcaacc tgcaaggcag gagataagat tattctgcca cgaaatgtcc
     9481 ataaatctgc tatcaatgcg ttggttctat gtggtgccat tcccatctat atcgagatga
     9541 gtgtagatcc taagattggt atcgctttag gtcttgaaaa tgaccgagta gcacaggcca
     9601 taaaggacca tccagatgct aaggctatcc taatcaacaa tcctacttac tacggcatct
     9661 gttcagacct aaaggggttg acagaaatgg ctcatgaagc tggcatgatg gttttagtag
     9721 atgaagccca tggagcgcat ttgcatttca ctggtaaact tccaatttct gctatggatg
     9781 caggagctga tatggcagca gtttccatgc ataagtctgg tgggagtttg acacaaagtt
     9841 cgcttctttt aatcggggag cagatgaatc ccgaatacgt tcgtcagatt ataaacctga
     9901 cccagtctac atctgcctct tacttattga tggctagttt ggatatttca cgtcgcaact
     9961 tggcccttcg tggtaaagag tcgtttgagg aagtcattga gctatccgag tacgctcgtc
    10021 atgaaatcaa tgccattggc ggttactatg cttactcaaa agagttaata gatggtgtgt
    10081 cggtctgtga ttttgatgta accaagttgt cagtttacac tcagggaata ggcttaacag
    10141 gtatcgaggt ttatgacctc ttgcgagacg aatacgacat tcagatcgag tttggtgata
    10201 tcggcaatat cttggcctat atttccatcg gcgaccgcat ccaagacatc gagcgcttgg
    10261 ttggtgctct ggctgatatt aagagactct attcacgaga tgggaaggac ttaatagctg
    10321 gagaatatat tcagcccgag ttggtgctgt ctccacaaga agccttctat tcagagagaa
    10381 aaagtttgac cttagatgag tctgttggac aggtctgtgg agaatttgtc atgtgctatc
    10441 ctccagggat tcctatcttg gctcctggtg aacgcattac acgagaaatt gtagactata
    10501 tccaattcgc caaggaacgt ggttgctccc tccaagggac ggaagatcca gaggtcaatc
    10561 atatcaacgt tattaagaga aagacaaact ataagaaaag tcaatagttt tatctaaact
    10621 atttcttatt tcaatttgat gatttggcga tgattttaga gcacggcaaa aagcccttga
    10681 attagaagcg gtcaatcgct taatttctat cagcttatca aatcctgcct caatcctttt
    10741 ctgaggatta gggtagcgtg tcaagagttg gtaggtatat tctgaatgct ttccaacgat
    10801 tttatccaac tcaggaaaga tgatatcaag acaacgagtg tattgtactt tccaatcaga
    10861 ctgtttttct tgagacgatg aatatgtcta gccagtattt ttagttctac ttgccgatta
    10921 tcgtgttgaa attgttcacg attggggtca gaaagaagtt taagagcgat gccatgagcg
    10981 tctttcttat ccgttttagt cttgcgaagt gataatgatt tggcaaattc cttgatgagc
    11041 aaaggattgc aggtgtaaac tttatatcct tgttcatgca ggaagttcag tagattaaag
    11101 gcataatgtc cggtattttc aagagcgatg agacagtctt ggttgagttg tcgaagagac
    11161 agatctaaga gttcaaaacc agctttatta tttgaaaaag tgagtggttt aagaacagtt
    11221 tttcctggaa cattcaaggc tgtaacatcg tgtttatttt tagcgacatc aatgcccaca
    11281 taaagcatgg gagtacctcc agatgtagta tttcaagtct acttggttat ccacgaattt
    11341 tttgccttgt taccttagac gagataaaac gtctatgcgt tatcaaactc attaccaatt
    11401 gaaacaaaaa actgtggtta gagcctttcg gaaatcgtca agcgattgga gggaataaac
    11461 taatccacag tggcttattc caagtatacc acttgggctt tggcagtagc taactgcgct
    11521 aaatataata taaggagaaa tagatggatt tatggttttc tgaagttcat actccagatg
    11581 tcaaattgtc tctgagaaca gccaagcaac tttacgctgg aaaaagtgaa tggcaggata
    11641 tcgaagtctt ggatacgcca gcttttggga aaatactgat tttaaatggc catgtcttgt
    11701 tctcagatgc ggatgatttc gtctacaatg aaatgaccgt tcacgttccc atggctgtcc
    11761 acccaaatcc aaagaaagta ttggttattg ggggtggtga cggcggtgtt gcccaagtat
    11821 taacactcta tcctgaactg gaacaaatcg atatcgtgga accggatgag atgttggtcg
    11881 aggtctgtcg tgagtatttc ccagactttg ctgcagggct agatgatcct cgtgttacca
    11941 tttactacca aaatgggcta cgctttttgc gaaactgcga agatgattac gatattatca
    12001 tcaacgatgc gacagatcca tttggccata cggaaggact ctttaccaag gaattctacg
    12061 gcaatagtta tcgagctctg aaggaagacg gcatcatgat ttaccagcat gggagtccct
    12121 tctttgacga ggatgagtcg gcctgccgaa gcatgcaccg caaggtcaat caatcctttc
    12181 caatcagtcg ggtttatcag gcccatattc caactagccc agctggctat tggttgtttg
    12241 gatttgcatc gaaaaaatac caccctgtca aagattttga caaggaaggt tggaaaaaac
    12301 gccagctttt cacagaatac tacactgcaa acttacacgt gggatccttt atgttgccca
    12361 agtatgttga ggacatttta gaagaagagg aaggaaaaaa atgagtcgtt tactagttat
    12421 tggttgtggg ggcgttgccc aagttgctat ttcaaagatt tgtcaagata gcgaaacatt
    12481 tacagagatt atgattgcta gccgtaccaa gtcaaaatgc gatgacttga aagcgaagct
    12541 agaaggcaaa acaagtacta aaattgaaac tgcagcactt gatgctgaca aggttgaaga
    12601 agtgattgcc ctgattgaaa gctacaaacc agaagctgtt ttgaatgtag ctctgcctta
    12661 tcaagattta accattatgg atgcttgttt ggcaacaggt gttcactata tcgatacagc
    12721 caactacgaa gcagaagaca cagaagaccc tgagtggcgt gctatctacg aaaaacgttg
    12781 taaggaactt ggttttacag cctactttga ctactcatgg cagtgggctt atcaagagaa
    12841 attcaaagaa gcaggcttga ctgctcttct tggttctggc tttgacccag gtgtaactag
    12901 tgtcttttca gcttatgccc tcaaacacta ttttgatgaa atccattata tcgacatttt
    12961 agactgtaat ggcggtgacc acggttatcc atttgcaacc aactttaatc cagaaattaa
    13021 tctccgtgag gtttctgcgc caggttctta ctgggaagat gggaaatggg tcgaagtcga
    13081 agctatgtct atcaagcgtg agtatgattt ccctcaagtt ggacaaaaag atatgtatct
    13141 ccttcaccat gaagaaatcg aatcattggc caagaacatt ccaggtgtca aacgcattcg
    13201 tttctttatg acttttggtc aatcttactt gacgcacatg aaatgtcttg aaaatgttgg
    13261 actccttcgt acggatacca ttaactttaa cggccaagaa attgttccaa ttcaattttt
    13321 gaaagccttg cttccagatc ctgctagcct tggcccacgt actgtaggta aaaccaatat
    13381 tggatgtatc tttacaggtg tcaaagatgg cgttgaaaag actatctaca tctacaatgt
    13441 ttgcgaccat caagagtgct atgcagaagt cgggtcacaa gcaatttcat acacgacagg
    13501 cgttccagcc atgattggga caaaattagt catgaacgga acttggaaac aagctggagt
    13561 gtataacctt gaggagttag atccagatcc attcatggaa gctttgaatg agtatggttt
    13621 gccatgggtt gtggttgaaa atccacaaat ggtggactaa tgaagttaga acaagtacca
    13681 acaccagcct atgttattga cttggccaag ttagaagcta attgccgcat tctacaatat
    13741 gtacaagaag aggtcggttg caaggtcttg cttgcccaga aggcatattc cctctacaaa
    13801 acttatccct tgattagcca gtatctatca ggtacgacag ctagtggact ctatgaggcc
    13861 aaattggcaa gggaagaatt tcctggtgaa gtccatgtat ttgcgcctgc tttcaaggat
    13921 gcagacttgg aggaattgct tgggataaca gaccatatcg tctttaactc agagagacag
    13981 ttgcgtaagc atggggctcg ttgtcgagag gctggtgtca gtgttggttt gcgcctcaac
    14041 cctcagtgtt caactcaagg agatcacgcg ctctatgacc cttgtgcacc aggttctcgc
    14101 tttggagtta ctatagacaa gattccgagt gatttgctag atttggttga cggacttcat
    14161 tttcataccc tttgcgagca gggagcagat gatttacaaa caactttgaa agcagtagaa
    14221 gaacagtttg gtccctactt acatgaggta aaatggctca atatgggtgg tggtcatcat
    14281 attacaagag aaggttacga tgtggatttg ctgatttcag aaatcaagcg tatccgaaaa
    14341 acttacaatc ttgaaatcta tatcgagcct ggtgaagcca ttgcgcttaa tgcgggttat
    14401 ttagcaactg aggtattaga tattgtagaa aacggtatgg aaatcttggt tttagacgcc
    14461 tctgcgacct gccatatgcc tgatgtactt gagatgccct atcgtccacc tttgagaaat
    14521 ggctttgagg cacaggaaaa agcccatacc tacagacttt cttctaatac ctgtctgacg
    14581 ggcgatgtga ttggtgatta tagttttgaa aatccagtcc aaatcggaga cagactttat
    14641 tttcaagaca tggccattta ttcttttgtc aaaaataata cctttaatgg tattggattg
    14701 ccaagtctct atctcatgga cgaacaggga gactgtagct tactcaaagc ttttggctat
    14761 caagacttta aagggagatt atcatgatgg acagtccaaa aaaattaggc tatcacatgc
    14821 cagcagagta cgaaccccat catggtaccc tcatgatatg gccgactcga ccaggatcat
    14881 ggccttttca aggaaaggat gctaaaagag catttactca gatcatcgag actatagcag
    14941 aaggggaaag agtctatctt ttggtggagc aggcctatct atctgaagcc caatcctatc
    15001 ttggggacaa ggttgtttat ttagacattc ccaccaatga tgcctgggcg cgtgatactg
    15061 gcccaaccat tctcgtcaat gataaaggta agaaattagc cgtggattgg gccttcaatg
    15121 cttggggagg cacctatgat ggtctttatc aagattatga agaggatgac caagtagcca
    15181 gtcgttttgc tgaggccttg gaaaggcctg tctatgatgc taaacctttt gtactggaag
    15241 gaggtgcaat ccatagcgat ggtcaaggaa ctattctcgt aactgaaagt tgcttgctta
    15301 gtcctggtcg caatcctaac ttgactaaag aggagattga aaacacatta ttagaaagtc
    15361 ttggtgctga aaaagttatt tggcttcctt atggtattta tcaggatgaa accaatgaac
    15421 acgtcgataa tgttgctgcc tttgttggtc ctgctgaggt tgttttggct tggacagatg
    15481 acgaaaatga tccccagtat gccatgtcaa aagcagatct cgaactctta gaacaggaaa
    15541 cagatgcaaa aggttgtcac ttcaccattc ataaattgcc tatccctgca gttcgacaag
    15601 ttgtgacaga agaagatttg ccaggctaca tctatgaaga aggagaagaa gagcgatacg
    15661 caggtgaacg actagcagct tcctacgtaa acttttatat cgccaacaag gctgtcttgg
    15721 ttccacagtt tgaggatgta aacgaccaag tggccttaga tatcctcagc aagtgtttcc
    15781 cagaccgtaa agttgtcgga ataccagcca gagatattct cttaggtggt ggcaatatcc
    15841 actgtatcac ccaacaaatt ccagaatagg agaaaaagat gagaaatgta agagttgcaa
    15901 ccattcagat gcaatgcgct aaggatgtgg caacaaatat ccaaaccgca gagcgtttag
    15961 tacgtcaggc tgctgagcaa ggagcccaaa ttattctctt gcccgagttg tttgaacatc
    16021 cctatttctg tcaggaacgt cagtatgact actaccagta tgcccaatct gtagcggaaa
    16081 atactgccat tcagcatttt aaggtgattg ctaaggaact acaagttgtt ttaccaatca
    16141 gtttctatga aaaagatggt aatgtcttgt ataactctat tgccgtcatt gatgcagatg
    16201 gggaagtgct gggcgtttat cgaaagaccc atataccaga tgaccattat tatcaagaaa
    16261 aattctattt cacgcctggt aacactggtt tcaaggtctg gaatactcgc tatgctaaga
    16321 ttggtatcgg tatctgttgg gatcaatggt tccctgaaac agcgcgctgt cttgcattga
    16381 atggtgctga attgctcttt tatcctacag ctatcggttc agagccaatt ttggatacag
    16441 atagttgtgg tcactggcaa cgtactatgc aagggcacgc agcagcgaat attgttccag
    16501 tcatcgcagc caatcgttat ggtttagagg aggttactcc tagtgaggaa aatggcggac
    16561 agagttccag tcttgacttc tacggttcct cctttatgac ggatgaaaca ggagctattc
    16621 tagaacgagc tgaaagacaa gaagaagctg ttctgttagc tacttatgac ctagacaagg
    16681 gagcaagtga acgtctaaac tggggcttgt ttcgagatag aagaccagaa atgtatagac
    16741 aaattacaga ttagtgtggg agaaatgaga gattcattct gctagactaa cttcttatta
    16801 gcaactataa gatactatgg catctagtaa atcgattttt atgattcgct attcttgtct
    16861 attgattagt ccgtatttta aatattagca aaaaagcaaa tagcagtaac ttctgtctat
    16921 ttgcttttct tttttataga atatatttct caatagcacg cgcaacgccg tcttcttcgt
    16981 tgcttgaggt aacggcatcc gcaagagatt tgacataatc gctggcattt cccattgcaa
    17041 tcccaagccc tgcaaactgg agcatttcga tatcgttatt agcatcgccc atggccataa
    17101 tctctgagga atcaatcttc aaaatctcag caagtcgtga aagagcagta gcctttgtcg
    17161 ttccaagtgg cattgcttca taaatgacag gctgcgaacg aactccactg aatcgttggc
    17221 aaagctcttc agcaaaacgc tgctcaaaat cgtctgtttg ttcttttgtt cctaaaaaca
    17281 taccttggaa catccggaac tttccactag tcgcttcttc aagagaaatt tcagtcaggt
    17341 ctgaaaatac tagtttagca tcattttcaa taacttgatt gggcttgcca ccgagaacaa
    17401 aataatgtga ctcgtcaaaa agtgtcaact gaacatcact cttttcagca aggtcataga
    17461 ggtattcgat gtcagctgga ctcagttctt gccagtcaac caagccccag tcgctagtct
    17521 ggtgagttga acaaccgttg ttaacaatca catattcgtt ctggaggtca agccccagtt
    17581 ttttgtagta ggggaggaca ccgaaaaggg ggcgacccgt acagaggacc agtttgacac
    17641 ctttttcaat ggcttggtga atagcagcga tgtgagcctg tgggatttcc ttggcttcat
    17701 tgaggagggt tccatccata tccaaggcta gtagtttaat cataggtctt ccttctttat
    17761 cttttggtat tattatagca tattttggag aagaaattga tagaaagctt gagactaatt
    17821 gattttatag tttaagatgt tttgatgaca attcatgatt tgaagaggat atttggcaaa
    17881 gatatgctat actatgtttg tcaatgttgc aactagacaa attaaaaaac caacttaata
    17941 taatagtttt tttgtaagta ggtatgagta tcagattact caactaatct aaacaataac
    18001 ggaggaaata tatcatgatt ttaatgacaa aaaatataaa tctaacaaat gaagaattag
    18061 agctgataca aggtggagca gatccctatg gtaaagaacc taatggttat tatccttggc
    18121 aaatggaacc agtattaact atgccggttc atggattttg tcccagagga accgatgatt
    18181 tagtatatat tgtaggaggt aatcatcttt gcaaaggaag tgctgcgaga ttttaagtaa
    18241 aatttattag gaatatgaag aaacaagggg agaaaacaga ggatttaata tgaaaaaacg
    18301 agctattcaa attttactag cattgtcctt aattttttac aaatcaactt ggttttggag
    18361 gcttttcaat tatctcgcaa agccctatct accagcaagt cgtgaatttt ttcagattct
    18421 acttttgctg gaaagtggtg ttcttttgtc agcagtcatc tatctactag tttttgcagg
    18481 aaagaagatt tttcatttca agtggcagtt gaggtacttt atctaccttt tactgggcta
    18541 catcatttcg tatatgtctg actttctctt ttcgtatttc atatccccgc cttcaaatca
    18601 aatttctttg aatgaaacga tagaaatgat gggacgacag gagttccctt atttcttgct
    18661 catcgtttgc ttcatcgccc ctattgctga ggaattgatt tatcgcggtg tgattatgac
    18721 aacctttttc aaaaactcgc cttggtacgg agatgttttg ctttctgcta ttattttcgg
    18781 ttatattcat atcaattttg ctttaactcc tcttgctttt ttcatttatg ctagtggagg
    18841 tcttatttta gctctattgt atcgcatgac taaaaatctc tactatccaa tactagttca
    18901 tattctcatc aatatcactg ccttctggga tgtttggtta ctcctatttt caggaagtta
    18961 gcttactaaa aaaatgtcgg aattttccgg cattttcttt tttcacaaat agtcaacgtt
    19021 tttctttccg atactgaagt ggtgtgtagc cacttatttt tttgaattga ttttgaaaat
    19081 aagattggcg tgagaaaggc agatagtgaa gatagttaag aagaatagga tgttcttttt
    19141 tcctttttgg aaaacttcta aaatatggta taatgaaaag ataaagaagt tgggggtaga
    19201 agatgaacat tcaacaatta cgctatgttg tggctattgc caatagtggt acttttcgtg
    19261 aagctgctga aaagatgtat gttagtcagc cgagtctgtc tatttctgtt cgtgatttgg
    19321 aaaaagagtt gggctttaag atttttcgtc ggaccagctc agggactttc ttgacccgtc
    19381 gtgggatgga attttatgaa aaagcgcaag aattggttaa aggatttgat atttttcaaa
    19441 atcagtatgc caatcctgaa gaagaaaaag atgaattttc cgttgctagc cagcactatg
    19501 acttcttacc accaactatt acggcctttt cagagcgcta tcctgactat aagaacttcc
    19561 gtatttttga atcaactact gttcaaatat tagatgaagt ggcgcaaggg catagtgaga
    19621 ttgggattat ctacctcaac aatcaaaata aaaaggggat tatgcaacgg gttgaaaagt
    19681 taggtctgga ggtcatcgaa ttgattcctt tccataccca tatttatctc tgtgagggtc
    19741 atcctttagc ccagaaagag gaattagtca tggaggattt agcggattta ccaacggttc
    19801 gtttcactca agagaaagac gagtaccttt attattcaga gaactttgtt gataccagcg
    19861 ctagctcaca gatgtttaat gtgacagacc gtgccacctt gaatggtatt ttggagcgga
    19921 cggacgccta tgcgacaggt tctggatttt tagatagtga cagtgttaat ggcattacag
    19981 ttattcgtct caaggataac ctagataacc gcatggtcta tgttaaacgt gaagaagtgg
    20041 agcttagtca agctgggact ctcttcgtag aagtcatgca agaatatttt gatcaaaaga
    20101 ggaaatcatg aaaaaaagag caatagtggc agtcattgta ctgcttttaa ttgggctgga
    20161 tcagttggtc aaatcctata tcgtccagca gattccactg ggtgaagtgc gctcctggat
    20221 tcccaatttc gttagcttga cctacctgca aaatcgaggt gcagcctttt ctatcttaca
    20281 agatcagcag ctgttattcg ctgtcattac tctggttgtc gtgataggtg ccatttggta
    20341 tttacataaa cacatggagg actcattctg gatggtcttg ggtttgactc taataatcgc
    20401 gggtggtctt ggaaacttta ttgacagggt cagtcagggc tttgttgtgg atatgttcca
    20461 ccttgacttt atcaactttg caattttcaa tgtggcagat agctatctga cggttggagt
    20521 gattatttta ttgattgcaa tgctaaaaga ggaaataaat ggaaattaaa attgaaactg
    20581 gtggtctgcg tttggataag gctttgtcag atttgtcaga attatcacgt agtctcgcga
    20641 atgaacaaat taaatcaggc caggtcttgg tcaatggtca agtcaagaaa gctaaataca
    20701 cagtccaaga gggtgatgtc gtcacttacc atgtgccaga accagaggta ttagagtatg
    20761 tggctgagga tcttccgcta gaaatagtct accaagatga ggatgtggct gtcgttaaca
    20821 aacctcaggg aatggttgtg cacccgagtg ctggtcatac cagtggaacc ctagtcaatg
    20881 ccctcatgta tcatattaag gacttgtcgg gtatcaatgg ggttctgcgt ccagggattg
    20941 ttcaccgtat tgataaggat acgtcaggtc ttctcatgat tgctaaaaac gatgatgcgc
    21001 atctagcact tgcccaagaa ctcaaggata aaaagtctct ccgcaaatat tgggcgattg
    21061 ttcatggaaa tctgcctaat gatcgtggtg taattgaagc gccgattggc cggagtgaaa
    21121 aagaccgtaa gaaacaggct gtaactgcta aagggaagcc tgcagtgacg cgttttcacg
    21181 tcttggaacg ctttggcgat tatagcttag tagagttgca actggagaca gggcgcactc
    21241 atcaaatccg tgtccacatg gcttatatcg gccattcagt cgctggtgat gaggtctatg
    21301 gtcctcgcaa gactttgaaa ggacatggac aatttcttca tgccaagact ttaggtttta
    21361 ctcatccgag aacaggtaag accttggaat ttaaagcaga tatcccagag atttttaagg
    21421 aaaccttgga gagattgaga aagtaagaat gaaaaagaaa ttaactagtt tagcacttgt
    21481 aggcgctttt ttaggtttgt catggtatgg gaatgttcag gctcaagaaa gttcaggctc
    21541 aagaaagttc aggaaataaa atccacttta tcaatgttca agaaggtggc agtgatgcga
    21601 ttattcttga aagcaatgga cattttgcca tggtggatac aggagaagat tatgatttcc
    21661 cagatggaag tgattctcgc tatccatgga gagaaggaat tgaaacgtct tataagcatg
    21721 ttctaacaga ccgtgtcttt cgtcgtttga aggaattggg tgtccaaaaa cttgatttta
    21781 ttttggtgac ccatacccac agtgatcata ttggaaatgt tgatgaatta ctgtctacct
    21841 atccagttga ccgagtctat cttaaaaaat atagtgataa tcgtattact aattctgaac
    21901 gtctatggga taatctgtac ggttatgata aggttttaca gactgctgca gaaaaaggtg
    21961 tttcagttat tcaaaatatc acacaagggg atgctcattt tcagtttggg gacatggata
    22021 ttcagctcta taactatgaa aatgaaaccg attcatcggg tgaattaaag aaaatttggg
    22081 atgataattc caattccttg attagtgtgg taaaagtcaa tggcaagaaa atttaccttg
    22141 ggggcgactt agataatgtt catggagcag aagacaagta tggtcctctc attggaaaag
    22201 ttgatttgat gaagtttaat catcatttag atacaaaaaa ttctaataca aaaaatttta
    22261 taaaaaattt gtctcctgag ataattgttc aaacttcctc ctcaccaatt ggttcgtatg
    22321 atagcggtca agaaataaat agggaatata ttagttggct tgaatcaatg ggaattcaac
    22381 atataaatgc agccagcaaa gactatgatg caacagtttt tgatattcga caagacggtt
    22441 taataaacat ttcaacttcc tacaagccta ttccaagttt tcaagctggt tggcataaga
    22501 gttcatatgg aaactggtgg tatcaagcgc ctgattctac aggagaatat gctgttggtt
    22561 ggaatgaaat taagggtgaa tggtattact ttaaccaaac gggtatctta ttacagaatc
    22621 aatggaaaaa atggaacaat cgttggttct atttgacaga ctctggtgtt gctgctaaaa
    22681 attggaagaa aatcgctgga atctggtatt attttaacaa agaaaaccag atggaaattg
    22741 gttggattca agataaagag cagtggtatt atttggatgt tgatggctct atgaagacag
    22801 gttggcttca atataagggg caatggtatt actttgctcc atcaggggaa atgaaaacgg
    22861 gctgggtaaa agataaagaa gcctggtact atatggattc tactggtatc atgaagacag
    22921 gtgagataga agttgctgga catcattact atctagaaga atcaggagct atgaagcaag
    22981 gctggcataa aaaggcaaat gattggtatt tctacaagac agacggttca cgagctgtgg
    23041 gttggatcaa ggacaaggat aaatggtact tcttgaaaga aaatggtcaa ttacttgtga
    23101 acggtaagac accagaaggc tatactgtgg attcaagtgg tgcctggtta gtggatgttt
    23161 cgatcgagaa atctgctaca attaaaacta caagtcattc agaaataaaa gaatccaaag
    23221 aagtagtgaa aaaggatctt gaaaataaag aaacgagtca acatgaaagt gttacaaatt
    23281 cttcaactag tcaagatttg acatcctcaa cttcacaaag ctctgaaacg agtgtaaaca
    23341 aatcggaatc agaacagtag tagaaaagaa ggttttaggg ccttcttttt cctatcaact
    23401 cttttctatt tcctgttatt catgttataa tggataaata tgaataatcg gagtgagact
    23461 atgaaataca aacggattgt ctttaaggtg ggtacttctt ctctgacaaa tgaggatgga
    23521 agtttatcac gtagtaaggt aaaggatatt acccagcagt tggctatgct gcacgaggct
    23581 ggtcatgagt tgattttggt gtcttcaggt gccattgcgg ctggttttgg agccttagga
    23641 tttaaaaagc gtccgactaa gattgctgat aaacaggctt cagcagcggt agggcaaggg
    23701 cttttgttgg aagaatatac aaccaatctt ctcttgcgtc aaatcgtttc tgcacaaatc
    23761 ttgctgaccc aagatgattt tgtggataag cgtcgttata aaaatgccca tcaggctttg
    23821 tcggttttac tcaaccgtgg ggcaattcct atcatcaatg agaatgatag tgtcgttatt
    23881 gatgaggtca aggttgggga caatgacact ctaagtgccc aagtagcggc gatggtccaa
    23941 gcagaccttt tggttctctt gacagatgtg gacggtctct atactggaaa tcctaattca
    24001 gatccaagag ccaaacgctt ggagagaata gagaccatca atcgtgagat tattgatatg
    24061 gctggtggag ctggttcgtc aaacggaact gggggtatgt taaccaaaat caaggctgca
    24121 actatcgcga cggaatcagg agttcctgtt tatatctgct catccttgaa atcagattcc
    24181 atgattgagg cggcagagga gaccgaggat ggttcttact ttgttgctca agagaagggg
    24241 cttcgtaccc agaaacaatg gcttgccttc tatgctcaga gtcaaggttc tatttgggtt
    24301 gataaagggg ctgcggaagc tctctctcaa catggaaaga gtcttctctt atctggtatt
    24361 gttgaagcag aaggagcctt ttcttacggt gatatcgtga cagtatttga caaggaaagt
    24421 ggaaaatcac ttggaaaagg acgcgtgcaa tttggagcat ctgctttgga ggatatattg
    24481 cgttctcaaa aagccaaggg tgtcttgatt taccgtgacg actggatttc cattactcct
    24541 gaaatccaac tactttttac agaattttag aggtaaacta tggtgagtag acaagaacaa
    24601 tttgaacagg tacaggctgt taaaaaatcg attaacacag ctagtgaaga agtgaaaaat
    24661 caagccttgc tagccatggc tgatcactta gtggctgcta ctgaggaaat tttagcggct
    24721 aatgccctcg atatggcagc ggctaagggg aaaatctcag atgtgatgtt ggatcgtctt
    24781 tatttggatg cagatcgtat agaagcgatg gcaagaggaa ttcgtgaagt ggttgcctta
    24841 ccagatccaa tcggtgaagt tttagaaaca agtcagcttg aaaatggttt ggttatcaca
    24901 aaaaaacgtg tagctatggg tgtcatcggt attatctatg aaagccgtcc aaatgtgacg
    24961 tctgatgcgg ctgctttgac tcttaagagt ggaaatgcgg ttgttcttcg tagtggtaag
    25021 gatgcctatc aaacaaccca tgccattgtc acagccttga agaagggctt ggagacgact
    25081 actattcacc caaatgtgat tcaactggtg gaagatacta gccatgaaag tagttatgct
    25141 atgatgaagg ccaagggcta tctagacctc ctcattcctc gtggaggagc tggcttgatc
    25201 aatgcagtgg ttgagaatgc gattgtacct gttatcgaga cagggactgg gattgtccat
    25261 gtctatgtgg ataaggatgc agacgaagac aaggcgctgt ctatcatcaa caatgctaaa
    25321 accagtcgtc cttctgtttg taatgccatg gaggttctgc tggttcatga agataaggca
    25381 gcaagcatcc ttcctcgctt ggatcaaatg ctggttgcag agcgtaagga agctggactg
    25441 gaaccaattc aattccgctt ggatagcaaa gcaagccagt ttgtttcagg tcaagcagct
    25501 gagacccaag actttgacac cgagttttta gactatgtcc ttgctgttaa ggttgtgagc
    25561 agtttagaag aagcggttgc gcacattgaa tcccacagca cccatcattc ggatgctatt
    25621 gtgacggaaa atgctgaagc tgcagcatac tttacagatc aagtggactc tgcagcggtg
    25681 tatgttaatg cctcaactcg tttcacagat ggaggacaat ttggtcttgg ttgtgaaatg
    25741 gggatttcta ctcagaaatt gcacgcgcgt ggtccaatgg gcttgaagga attgactagc
    25801 tacaagtatg tggtcactgg tgatggacag ataagggagt aagagatgaa gattggattt
    25861 atcggtttgg ggaatatggg tgctagttta gccaagtctg tcttgcaggc tagaccgtca
    25921 gatgagattc tccttgccaa tcgtagtcaa gtcaaggtgg atgctttcat cgctaacttc
    25981 ggtggtcaga cttctaacaa tgaagaaata ttcgaagaag cagatgtgat ttttctaggt
    26041 gttaagcctg ctcagttttc tgaactgctt tctcaatacc agaccatcct tgaaaaaaga
    26101 gaaagtcttc ttttgatttc gatggcagct ggattgatct tagaaaaact agcaagtctt
    26161 atcccaagcc aacaccgaat tattcgtatg atgcctaata cccctgcttc tatcgggcaa
    26221 ggagtgatta gttatgcctt gtctcctaat tgcagggctg aggacagtga gctcttttgt
    26281 cagcttttat ccaaggctgg tctcttggtt gaattaggag aaagcttaat caatgcagcg
    26341 acaggtcttg caggctgtgg accagccttt gtctatctct ttattgaggc cttggcagat
    26401 gcaggtgttc agacgggatt accacgagaa acagccttga aaatggcagc ccaaactgtg
    26461 gtaggagctg ggcaattggt cctagaaagc cagcaacatc ctggagtttt gaaagatcaa
    26521 gtttgtagtc caggcggttc gactattgct ggcgtagcaa gcctagaagc gcatgctttt
    26581 cgaggaacgg tcatggaggc agttcatcaa gcctataaac gaacacaaga actaggtaaa
    26641 taagaggtag ttttatctgc ctcttttatg gtggttgata ctcttcgaaa atcaaattca
    26701 aactgcgtca gcttcacctt gccgtactca agtacagcct gcggctagct tcctagtttg
    26761 ctctttgatt ttcattgagt atgaaatgag aagacaaaaa gattgtcaca aacccctatt
    26821 tttttgatag aatagaagta gtaaaaaaga aatgagttag acatgtcaaa aggattttta
    26881 gtctctcttg agggaccaga gggagcaggc aagaccagcg ttttagaggc tctgctacca
    26941 attttagagg taaaaggggt aaaggtgctg acgacccgtg aacctggcgg agtcttgatt
    27001 ggggagaaga ttcgggaagt gattttggat ccaagtcata ctcagatgga tgctaaaaca
    27061 gagctacttc tctatattgc cagtcgcaga cagcatttgg tggaaaaagt tcttccagcc
    27121 cttgaagctg gcaagttggt catcatggat cgttttatcg atagttctgt tgcctatcag
    27181 ggatttggtc gtggcttaga tattgaagcc attgactggc tcaatcagtt tgcgacagat
    27241 ggcctcaaac ccgatttgac actctatttt gacatcgagg tggaagaagg gctggctcgt
    27301 attgctgcta atagtgaccg cgaggttaat cgtttggatt tggaagggtt ggacttgcat
    27361 aaaaaagttc gtcaaggcta cctttctctc ctggaaaaag aaggaaatcg cattgtcaag
    27421 attgatgcta gtctcccttt ggagcaagtt gtggaaacta ccaaggctgt cttgtttgac
    27481 ggaatgggct tggccaaatg aaacaagatc aactaaaggc ttggcaacca gctcagtttg
    27541 accgttttgt ccgtatctta gaacaagacc agctcaatca cgcctatctc ttttcaggtt
    27601 tctttggaag cttggaaatg gcgcaatttt tagctaagag cctcttttgt acggataaag
    27661 ttggcgtctt accatgtgag aaatgccgaa gttgcaagct gattgaacag gaagagtttc
    27721 cagatgtcac cttgattaag ccagtcaatc aggtcatcaa gacagaacgc attcgggaat
    27781 tggtgggaca gttttctcaa gcagggattg aaagccagca acaggtcttt atcatcgagc
    27841 aagcggataa aatgcatccc aacgcagcca attctctgct caaggtcatc gaagaacccc
    27901 agagtgaagt ttatattttc ttcttgacta gcgatgagga aaagatgtta ccgacaatcc
    27961 gaagtcggac tcagatcttc cactttaaaa agcaagaaga aaaacttatc ttactcttag
    28021 aacaaatggg acttgttaag aaaaaagcga ctcttttagc taagtttagt caatcgcgag
    28081 ctgaagcaga aaagttggct aatcaggcaa gtttttggac cttggtcgat gaaagtgaac
    28141 gcctgctgac ttggttagta gctaagaaaa aagaaagtta tctacaggtt gccaaattag
    28201 ccaacttggc agatgataag gaaaaacagg atcaggtttt acggattctt gaagttctct
    28261 gtgggcagga cctcttgcag gtaagagtaa gagtgattct acaagattta ctagaagcta
    28321 gaaaaatgtg gcaagctaat gtcagctttc aaaatgccat ggaatatctg gtcttgaaag
    28381 aaatataaac tcaaaaatga atgataaaga aaggaaaggg ctgttttatg gacaaaaaag
    28441 aattatttga cgcgctggat gatttttccc aacaattatt ggtaacttta gccgatgtgg
    28501 aagccatcaa gaaaaatctc aagagcttgg tagaagaaaa tacagctctt cgcttggaaa
    28561 atagtaagtt gcgagaacgc ttgggtgagg tggaagcaga cgctcccgtc aaggccaagc
    28621 atgttcgcga aagtgtccgt cgtatttacc gtgatggatt tcacgtatgt aatgattttt
    28681 atggacaacg tcgagagcag gacgaagaat gtatgttctg tgatgagttg ttatacaggg
    28741 agtaagcatg cagattcaaa aaagttttaa ggggcagtct ccctatggca agctgtatct
    28801 agtggcaacg ccgattggca atctagatga tatgactttt cgtgctatcc agaccttgaa
    28861 agaagtggac tggattgctg ctgaggatac gcgcaataca ggtcttttgc tcaagcattt
    28921 tgacatttcc accaagcaga tcagttttca tgagcacaat gccaaggaaa aaattcctga
    28981 tttgattggt ttcttgaaag cagggcaaag tattgctcag gtctctgatg ccggtttgcc
    29041 tagcatttca gaccctggtc atgatttggt taaggcagct attgaggaag aaattgcagt
    29101 tgttacagtt ccaggtgcct ctgcaggaat ttccgccttg attgccagtg gtttagcgcc
    29161 gcagccacat atcttttacg gctttttacc gagaaaatca ggccagcaaa agcaattttt
    29221 cgactcgaaa aaagactatc ctgaaactca gattttttat gaatcgcccc atcgtgtggc
    29281 agatacattg gaaaatatgc tagaagtcta cggtgaccgc tcggtagtct tggttagaga
    29341 attgaccaaa atctatgaag aataccaaag aggtacaatt tctgaattgc tggaaagcat
    29401 ctctgaaacg tctctcaagg gtgaatgtct tctgattgtt gaaggtgcca gcaaaggtgt
    29461 ggaggaaaag gatgaggaag acttgttctt agaaatccaa gcccgtatcc agcaaggcat
    29521 gaagaaaaat caagctatta aggaagtcgc taagatttac cagtggaata aaagtcagct
    29581 ctacgctgcc taccacgact gggaagaaaa tcaagaaaat gactaaacag ggaagtttgc
    29641 cttcttccct ttttttgtta tactagtaga agaaaaaatt agaaagattt gtgggtgtta
    29701 aacaagccag tgccttgttt tgatatgaac ttaggttcca cccaaagagg tattagtgtc
    29761 gtgtctcaat cttatatcaa tgttatcggt gctggtttgg caggttctga agcagcttac
    29821 caaatcgcag agcgtggtat tccagttaaa ctatatgaaa tgcgtggtgt caagtctaca
    29881 ccccagcata aaacagacaa ttttgctgag ttggtttgtt ccaattcttt gcgtggggat
    29941 gctttgacaa atgcagttgg tcttctcaag gaagaaatgc gtcgcttggg ttctgttatc
    30001 ttggaatctg ctgaggctac acgtgttcct gccggtggag cccttgcggt ggatcgtgat
    30061 ggtttctctc aaatggtgac cgaaaaagtt gccaaccacc ccttgattga agtggttcgt
    30121 gatgaaatta cagaattgcc gacagatgtt attacggtta tcgctactgg tcctttgaca
    30181 agtgatgcct tggctgaaaa gattcatgcc cttaatgacg gtgatggttt ttatttctac
    30241 gatgcggcag cgcctattat cgatgtcaac actatcgata tgagcaaggt ctacctcaaa
    30301 tcacgttatg ataagggaga agcggcctac ctcaatgccc ctatgaccaa gcaagaattt
    30361 atggatttcc atgaagcttt ggtcaatgca gaagaagcac cgcttaattc ttttgaaaaa
    30421 gaaaagtact ttgaaggatg tatgcctatc gaagttatgg ccaaacgtgg cattaaaact
    30481 atgctttatg gccctatgaa gccagtcggt cttgagtatc cggacgacta cacaggacct
    30541 cgtgatggag aatttaaaac accttatgcg gttgtgcaac ttcgtcagga taatgcagct
    30601 ggtagcctct acaatatcgt tggtttccag acccacctca aatggggaga acaaaagcgt
    30661 gtcttccaaa tgattccggg tcttgaaaat gcggagtttg tccgttatgg tgtcatgcat
    30721 cgcaattctt acatggattc accaaatctt cttgagcaga cttaccgttc caagaaacaa
    30781 ccaaatctct tctttgctgg tcagatgacg ggggtggaag gctatgttga gtcggcggct
    30841 tcgggcttag ttgcgggaat taacgcagct cgtctcttca aggaagaaag cgaggttatt
    30901 ttccccgaga cgacagcgat tggaagctta gctcattaca ttacccatgc cgacagcaaa
    30961 catttccaac caatgaatgt caattttggg atcatcaagg agttggaagg cgagcgtatc
    31021 cgtgataaga aggctcgtta tgaaaaaatt gcagagcgtg cccttgccga cttagaggaa
    31081 tttttgactg tctaattttt ttgaaagaat tgctcatgat actataaaaa tcttagaaat
    31141 tgtgataaaa taggtaggat gaaagaagga gagtgaaaat ggcgaatccc aagtataaac
    31201 gtattttaat caagttatca ggtgaagccc ttgccggtga acgtggcgta gggattgata
    31261 tccaaacagt tcaaacaatc gcaaaagaga ttcaagaagt tcatagctta ggtatcgaaa
    31321 ttgcgcttgt tattggtgga ggaaatctct ggcgtggaga acctgcagca gaagcaggta
    31381 tggaccgtgt tcaggcagat tacactggaa tgcttgggac tgttatgaat gctcttgtga
    31441 tggcagattc attgcaacaa gttggggttg atacgcgtgt acaaacagct attgctatgc
    31501 aacaagtggc agagccttat gtccgtggac gtgcccttcg tcaccttgaa aaaggccgta
    31561 tcgttatctt tggtgctgga attggttcac catacttctc gacagataca acagcggccc
    31621 ttcgtgcagc tgaaatcgaa gcagatgcca tcctcatggc taaaaatggc gtcgatggtg
    31681 tgtacaatgc cgatcctaag aaggacaaga cagccgttaa gtttgaagaa ttgacccacc
    31741 gtgatgttat caacaaaggt cttcgtatca tggactcaac agcctcaacc ctctcaatgg
    31801 acaacgacat tgacttggtt gtcttcaaca tgaaccaatc aggcaacatc aaacgtgtcg
    31861 tatttggtga aaatatcgga acaacagttt caaataatat cgaagaaaag gaataagaaa
    31921 gaatatggct aacgtaatta ttgaaaaagc taaagagaga atgacccagt ctcaccaatc
    31981 acttgctcgt gaatttggtg gtatccgtgc tggtcgtgcc aatgcaagct tgcttgaccg
    32041 tgtacatgta gaatactatg gagtcgaaac tcctcttaac caaatcgctt caattacgat
    32101 tccagaagcg cgtgttttgt tggtaacacc atttgacaag tcttcattga aagacatcga
    32161 acgtgccttg aacgcttctg atcttggtat cacaccggct aatgacggtt ctgtgattcg
    32221 cttggttatc ccagctctta cagaagaaac tcgtcgtgac cttgctaaag aagtgaagaa
    32281 ggtcggcgaa aatgctaaag tggctgtccg caatatccgt cgcgatgcta tggacgaagc
    32341 taagaaacaa gaaaaagcaa aagaaatcac tgaagacgaa ttgaagactc ttgaaaaaga
    32401 tattcaaaaa gtaacagacg atgctgttaa acacatcgac gatatgactg ccaacaaaga
    32461 gaaagaactt ttggaagtct aaaaataaac agaaaaactc agttggcatt gctggctgag
    32521 ttttattcga aagaaggaaa tatgaataca aatcttgcaa gttttatcgt tggactgatc
    32581 atcgatgaaa acgaccgttt ttactttgtg caaaaggatg gtcaaaccta tgctcttgct
    32641 aaggaagaag gccaacatac agtaggggat acggtcaaag gttttgcata cacggatatg
    32701 aagcaaaaac tccgcctgac aaccttagaa gtgactgcca ctcaggacca atttggttgg
    32761 ggacgtgtca cagaggttcg taaggacttg ggtgtctttg tggatacagg ccttcctgac
    32821 aaggaaatcg ttgtgtcact cgatattctc cctgagctca aggaactctg gcctaagaag
    32881 ggcgaccaac tctacatccg tcttgaagtg gataagaaag accgtatctg gggtctcttg
    32941 gcttatcaag aagacttcca acgtcttgct cgtcctgcct acaacaacat gcagaaccaa
    33001 aactggccag ccattgttta ccgtctcaag ctatcaggaa cttttgttta cctaccagaa
    33061 aataatatgc ttggttttat tcatcctagc gagcgttacg cagagccacg tttggggcaa
    33121 gtattagatg cgcgcgttat tggtttccgt gaagtggacc gcactttgaa cctctccctc
    33181 aaaccacgct cctttgaaat gttggaaaac gatgctcaga tgattttgac ttatttggaa
    33241 agcaatggcg gtttcatgac cttaaatgac aagtcatctc cagacgacat caaggcaacc
    33301 tttggcattt ctaaaggtca gttcaagaaa gctttaggtg gtcttatgaa ggctggtaaa
    33361 atcaagcagg accagtttgg tacagagttg atttagggag gcttatgaga aaatcatttt
    33421 acacttggct catgaccgag cgcaatccta aaagtaacag tcccaaagca attttggcag
    33481 acctcgcttt tgaagagtca gcctttccaa aacatacaga tgattttgat gaggtcagtc
    33541 gctttttgga ggagcatgcc agtttctctt ttaacctagg agattttgac agcatttggc
    33601 aggaatatct agaacactag catttattca ttgggtttgg gctagtaatt tctccatccc
    33661 tctgctataa taaaaagaaa taaaaggatt agagaggttc tttatttgaa ggaacattca
    33721 atagacattc aactgagtca tccagatgac ctgtttcatc tttttggttc caatgaacgc
    33781 catcttcgtt tgatggaaga agagcttgat gttgtgattc atgctcgtac ggagattgtc
    33841 caggttttgg gagaagagtc tgcctgtgag gaagcccgtc aagttattca ggctttgatg
    33901 gtcttggtaa atcgtgggat gaccgttggt acgccagatg tagtcactgc gattagcatg
    33961 gtcaaaaatg atgaaattga caagtttgtc gccctttacg aagaagaaat tatcaaagat
    34021 aatactggga aacctatccg tgtcaaaacc ctagggcaaa agctttatgt ggacagtgtc
    34081 aaacagcatg atgtgacctt tggaattggg ccagcaggta cagggaagac cttccttgca
    34141 gtgaccttgg cagtgactgc ccttaaacgt gggcaagtca agcgaattat cctaactcgt
    34201 ccagcggtgg aagcgggaga gagtcttgga tttcttccgg gtgatcttaa ggagaaggtg
    34261 gatccttacc ttcgtcctgt ttacgatgcc ttgtatcaaa ttcttgggaa agaccaaacg
    34321 actcgtctca tggagcgtga aattatcgaa attgcgcccc ttgcctatat gcgtggtcgg
    34381 accttggatg atgcctttgt cattctcgat gaggcgcaaa atacgaccat catgcagatg
    34441 aagatgttct tgactcgttt aggttttcat tctaagatga ttgtcaatgg agatattagt
    34501 cagattgatc tgccacgtaa tgtcaagtcc ggtttgattg atgcccaaga aaagctcaag
    34561 aacatttacc aaattgactt tgttcatttt tcagctaagg atgtggttcg ccatccagtt
    34621 gtcgctcaga ttatccgagc ttatgaacca gctccagtta aaaaagaaga gagtgaagaa
    34681 ttagagtctc aacctctgtc tgaaggatag ttcttttgta cttaaagtta tctcaatgct
    34741 aagtataaat ttgcttttta aatgttttat tcaatatcct tatattagat tagaaacgtt
    34801 tcaagcggag gaaacgtatg gaatcaatat ttgtgaaatt tgcccagtat ccgtctatag
    34861 aaacggagcg tttattgctt agacctgtaa ctttggatga tgcggaagca atgtttgact
    34921 atgcctcgga caagggtaat acacgttaca cttttccaac caatcaaagc ttggaagaaa
    34981 ccaagaataa cattgctcag ttctatttgg ctaatccctt gggacgttgg ggaatagaac
    35041 taaaaagcaa tggtcagttt attggaacca ttgacttgca caagattgat tctgttctta
    35101 agaaggcagc tattggctac attatcaata aaaagtattg gaatcaagga ttaacgacag
    35161 aagccaatcg tgctgtgatt gagctagctt ttgagaagat agggatgaat aagttgactg
    35221 cccttcacga taaggacaat cctgcgtcag gaaaggtcat ggagaaatca ggcatgcgtt
    35281 tttcccatgc agaaccatat gcttgtatgg accagcatga aaaagatcga atcgttacaa
    35341 gagttcatta tgtcttgacc aaggaagact attttgcaaa taaataagca gttgaaaaga
    35401 aatttttcga ctgttttttc ttcctcttac gaataatcta agagaggaga aaatatggaa
    35461 gcaattatcg agaaaatcaa agagtataaa atcatcgtca tctgtactgg tctgggcttg
    35521 cttgtaggcg gatttttcct gctaaagcca gctccacaaa cacctgtaaa ggaaacgaat
    35581 ttgcaggctg aagttgcagc tgtttccaag gatttggtat ccgaaaagga agtgaacaag
    35641 gaagagaagg aagaaccagt tgaacaagat ctaatcacag tagatgtcaa aggtgctgtc
    35701 aaatcgccag ggatttatga cttgcctgta ggtagtcgag tcaatgatgc tgttcagaag
    35761 gctggtggct tgacagagca agcagacagc aagtcgctca atctagctca gaaagttagt
    35821 gatgaggctc tggtttacgt tcctactaag ggagaagaag cagttagtca acagactggt
    35881 tcggggacag cttcttcaat aagcaaggaa aagaaggtca atctcaacaa ggccagtctg
    35941 gaagaactca agcaggtcaa gggactggga ggaaaacgag ctcaggacat tatcgaccat
    36001 cgtgaggcaa atggcaagtt caagtcagta gacgagctca agaaggtctc tggcattggt
    36061 ggcaaaacaa tagaaaagct taaagactat gttacagtgg attaagaatt tctctattcc
    36121 cctaatttac ctgagttttc tattactttg gctttattac gctattttct cagcatctta
    36181 tcttgctttg ttgggctttg tttttctgct agtctgtctc tttatccaat ttccgtggaa
    36241 atctgctggt aaagttctaa taatttgcgg aatctttgga ttttggtttg tttttcaaaa
    36301 ttggcaacag agtcaagcga gtcaaaatct ggcggattct gttgaaaggg tacggatttt
    36361 gcctgatact attaaggtta atggtgatag tctatccttt cgtggcaagt ctaacggtcg
    36421 tgctttccaa gtctattata aactccagtc cgaggaggag aaagaagcct ttcaagcttt
    36481 aaccgacctg catgagatag gactagaagg gaagctttcg gagccagaag ggcagagaaa
    36541 ttttggtggc tttaattacc aagcctatct gaagactcag ggaatttacc agactctcaa
    36601 tatcaaaaca atccagtcac ttcaaaagat tggcagttgg gatataggag aaaacttgtc
    36661 cagtttacgt cgaaaggctg tggtttggat taagacgcac tttccagacc ctatgcgcaa
    36721 ttacatgaca ggactcttgc tgggacatct ggacaccgac tttgaggaga tgaatgagct
    36781 ttattccagt ctaggaatta tccacctctt tgccctatct ggtatgcagg taggtttttt
    36841 catgaatgga tttaagaaac ttctcttgcg attgggcttg acccaagaaa agttgaaatg
    36901 gctgacttat cccttttccc ttatctatgc gggactaact ggattttcag catcggttat
    36961 tcgcagtctc ttgcaaaagc tactggctca acatggggtt aagggcttgg ataattttgc
    37021 cttgacggtg cttgtcctct ttattgtcat gccaaacttt ttcttgacag caggaggagt
    37081 cttgtcctgc gcttatgctt ttatcctgac catgaccagc aaagaagggg aggggctcaa
    37141 ggctgttact agtgaaagtc tagtcatctc cttgggcata ttgcccattc tatccttcta
    37201 ttttgcggaa tttcaacctt ggtctatcct tttgaccttt gtcttttcct ttctatttga
    37261 cttgaccttc ttaccgctct tgtctatttt atttgtcctt tcctttctct atccagtcat
    37321 tcagctgaac tttatctttg aatggttgga gggcattatt cgcttggtgt cacaggtgac
    37381 aagtagacct ctggtctttg gacaacccaa tgcatggttt ttaatcctat tgttaatttc
    37441 cttggctttg gtctatgatt tgagaaaaaa cattaaaaag ctaacggtat tgtgcttatt
    37501 gattacaggg ctctttctcc tgaccaagca tccactggaa aatgaaatca ccatgctgga
    37561 tgtggggcaa ggagaaagta ttttcctacg ggatgtaact gggaaaacca ttctcataga
    37621 tgtaggtggt aaggcagaat cttataagaa aatcgaaaaa tggcaagaaa agatgacgac
    37681 cagcaatgcc cagcgaacct tgattcccta tctcaaaagt cgaggagtag ctaagattga
    37741 ccagctaatt ttgactaaca cggacaagga gaatgttgga gatttgtcag aggtgaccaa
    37801 ggctttccat gtaggggaga ttctagtatc aaaagacagt ctgaaacaga aggaatttgt
    37861 ggcagaacta cagacgactc aaacaaaggt gcgtagtatg acagtagggg agaacttgcc
    37921 catttttgga agtcagttag aagttctatc tccaaggaaa atgggagatg gaggacacga
    37981 tgacacccta gttctgtatg ggaaattctt ggataagcaa tttctcttca cgggaaattt
    38041 ggaggagaaa ggagagaagg acttgctgaa gcactatcca gacttgaaag taaatgtttt
    38101 gaaagctagc caacatggca ataaaaaatc atcaagtcca gcctttctag aaaaactcaa
    38161 accagagctt actcttatct cagttggaaa gagcaatcga atgaaactcc cccatcagga
    38221 aacattgaca cgactggaag gtatcaatag caaagtttat cgaactgacc agcaaggagc
    38281 tatacgtttt aagggggtgg atagttggaa aatcgaaagt gttcgatagg aaggataaat
    38341 gttgtagatt agtgaaataa actaaaaatt tgttgcataa taatgataaa aatggtataa
    38401 tgaaaacgta ttcaatattg aggatataaa atcattaaaa atcagcaaaa gttgttttat
    38461 tagttagttt ataatctatt ggtcttcttc agtccagtgt atctgctgtg acagccacta
    38521 aaagttacaa gtatgattgg aatacggttt tggaatatag taccaactat cacgaccatc
    38581 agtatgcttg gattccggaa tggtctcgtt attacagcta ttctgagtat aaagttggcg
    38641 gaggctggaa ctacgctcgt tatgaggtca taaactacta tactggaagt tattaatcct
    38701 taaaaagtga gaaaaggagg gctggatatg ttaaatctta ctcatgttac cttaaaaacg
    38761 cgacaagtca tcttgcaaga tgcggatttt acctttaaaa agggtaggat ttatggcctt
    38821 cttgctatca atggctcggg aaagacgaca ctattccgag ctatgagtaa gttgcttccc
    38881 cttagtagtg gacacatcgc agttcctcct tctttgtttt attatgagag cgttgaatgg
    38941 ctggatggaa acttaagtgg gatggactac cttcgtctca taaaaaacat ctggaagtca
    39001 gacctaaact tgagagatga aatcgcctac tgggaaatgg ctgactatat cagtcttccc
    39061 atccgcaagt attccttagg catgaagcaa cgcttggtga ttgctatgta ttttctcagt
    39121 caggccaaat gctggctcat ggatgagatt acaaatggct tagacgagta ttatcgacag
    39181 aagttttttg ataggctagc acaaatcgat agacaagaac agctggttct tttaagttcc
    39241 cactataagg aagagttggt tgatatctgc gatagagtag taaccattca tcaggggcag
    39301 atagaagagg tttagtttat gaaagatgtt agtctatttt tattgaaaaa agttttcaaa
    39361 agtcgtttaa actggattat cttactttta tttgcatctg tactcggtgt taccttttat
    39421 ttaaatagtc agactgcaaa ctcacacagc ttggagagca ggttggaaag tcgcattgca
    39481 gccaacgaga gggctatcaa tgaaaatgaa gagaaactct cccaaatgtc tgataccagc
    39541 tcggaggaat accagtttgc taaaaataat ttagacgtgc aaaaaaatct tttgacgcga
    39601 aagatagaaa ttctgacttt actaaaagaa gggcgctgga aagaagccta ctatctgcag
    39661 tggcaagatg aagagaagaa ttatgaattt gtatcaaatg acccgactgc tagctctggc
    39721 ttaaaaatgg gggttgaccg cgaacggaag atttaccaag ccctgtatcc cttgaacata
    39781 aaagcacata ctttggagtt tccgacccac gggattgatc agattgtctg gattttagag
    39841 gttatcatcc caagcttgtt tgtggttgcg attattttta tgctaacaca actatttgca
    39901 gaaagatatc aaaatcatct ggacacagct cacttatatc ctgtttcaaa agtgacattt
    39961 gcaatatcct ctcttggagt tggagtggga tatgtaactg tgctgtttat cggaatctgt
    40021 ggcttttctt ttctagtggg aagtctgata agtggttttg gacagttaga ttatccctac
    40081 ccaatttata gcttagtgaa tcaagaagta actattggga aaatacaaga tgtattattt
    40141 cctggcttgc tcttagcttt cttagccttt atcgtcattg tggaagttgt gtacttgatt
    40201 gcttactttt tcaagcaaaa aatgcctgtc ctctttcttt cactcattgg gattgttggc
    40261 ttattgtttg gcatccaaac aattcagcct cttcaaagga ttgcacatct gattcccttt
    40321 acttacttgc gttcagtgga gattttatct ggaagattat ctaagcagat tgataatgtc
    40381 gatctaaatt ggagcatggg gatggtctta cttccttgcc tgattatcct tttgttagtg
    40441 gggattctat ttatcgaaag atggggaagt tcacgtaaaa aggaagtttt taaagtttag
    40501 ttttcctata gggaagctaa agaaaaacta acatagggag agaatcaact tgattctctc
    40561 tttttgattc gaaaaccaaa ccaaaataca aacacaaact tttcaaaaaa taacttttta
    40621 tcttgacaag agctagaaaa cttggtatca tataaaagtt gagaaaagca gaagtgagag
    40681 cttctcgcct tgtgacatta agttgcctgg ccctacggat gaaaagtttc gaagaaacgc
    40741 tatcataacg tgcgggcttg tatatttacg agtccgctat tgtttttctc taataaaaca
    40801 aaagaggtga aaaccatagc aaagcaagac ttattcatca atgatgagat tcgtgtacgt
    40861 gaagttcgct tgattggtct tgagggagaa cagctaggca tcaagccact cagtgaagcg
    40921 caagctttgg ctgataacgc taatgttgac ctagtattga ttcaacccca agccaaaccg
    40981 cctgttgcaa aaattatgga ctacggtaag ttcaaatttg agtaccagaa gaagcaaaaa
    41041 gaacaacgta aaaaacaaag cgttgttact gtgaaagaag ttcgtctaag tccaactatt
    41101 gacaagggtg actttgatac aaaacttcgt aatgcacgta agttccttga aaaaggaaat
    41161 aaagttaagg tatctattcg ctttaagggt cgtatgatta cccataaaga gattggtgca
    41221 aaagttttag ccgagtttgc tgaagcaact caagatattg ccatcatcga acaacgtgct
    41281 aaaatggatg gacgtcaaat gttcatgcaa ttggcgccag cgactgacaa aaaataattg
    41341 tcagaaagtt aaataaagga gaaaaaatca tgccaaaaca aaaaacacac cgcgcatcag
    41401 ctaaacgttt caaacgtaca ggttctggtg gacttaaacg tttccgtgct tacacttctc
    41461 accgtttcca cggaaaaact aagaaacaac gtcgtcatct tcgtaaagca tctatggtgc
    41521 attcaggaga ttacaaacgt atcaaagcaa tgcttactcg cttgaaataa tagcttgact
    41581 gtaagtaaac aattctagga aatatttgga ggaaataaaa catggcacgt gttaaaggtg
    41641 gcgttgtatc acgcaaacgt cgtaaacgta ttcttaaatt agcaaaaggt tactatggag
    41701 ctaaacacat cttgttccgt actgcaaaag aacaagtaat gaactcttac tactatgcat
    41761 accgtgaccg tcgtcagaaa aaacgtgact tccgcaaatt gtggattact cgtatcaatg
    41821 cggcagctcg tatgaacgga ctttcatact cacaattgat gcatggtttg aaattggctg
    41881 agattgaagt taaccgtaaa atgcttgctg acttggctgt taacgatgca gtagctttca
    41941 cagctcttgc agatgcagct aaagcaaaac ttggtaaata acaactgatg agactggaac
    42001 aggattgtcc agtcttttta aaaataaagg agaaagatat ggcttcaaaa atgctacaca
    42061 cttgcttacg agtagaaaat cttgaaaaat caatcgcatt ttatcaagat gcttttggtt
    42121 ttaaagaatt gcgtcgcaga gattttccag accatgcctt cacgattgtc tatctaggtc
    42181 ttgagggtga tgactatgag ttggagttga cttataacta cgatcacggt ccgtatgtgg
    42241 ttggtgatgg gtttgcccat atcgccctca gtacacctga tcttgaggca cttcatcaag
    42301 aacacagtgc aaaaggctat gaagtgactg agccaaatgg tctaccagga actacaccaa
    42361 actattactt tgtcaaagac cctgatggat ataaggtcga agtcattcgt gaaaaataat
    42421 ttcgtgcaag ttaagtagaa tattcgtttt ctacttgact ttttttagct gaaagagtat
    42481 actaataaaa attcaacctt taaggggagt ccagagagac tcacaaggtg tcagataaaa
    42541 gaatagtgca attttctaga ggagactttt tgagtgtgct ctcttgtgtt gtacgatttt
    42601 aactgaggcc ttgcactagc aaggtctttt ctttatctgg tccccttaaa atttaaggag
    42661 gaaaagttat gaatcccaca tgtaagaagc gtttgggtgt cattcggttg gaaaccatga
    42721 aggtggttgc acaagaggaa atcgcgccag caatctttga attagtccta gaaggagaaa
    42781 tggttgaagc catgcgagca ggccaatttc ttcatctgcg tgtaccggac gatgcccatc
    42841 tcttacgtcg tcctatttca atttcgtcta ttgacaaggc aaacaagcag tgtcacctca
    42901 tttatcggat tgagggagct gggactgcaa ttttttcaac cttaagtcag ggagacactc
    42961 ttgatgtgat ggggcctcag ggaaatggtt ttgacttgtc tgaccttgat gagcagaatc
    43021 aggttctcct tgttggtggt gggattggtg ttccaccctt gcttgaggtg gccaaggaat
    43081 tgcatgaacg tggagtgaaa gtagtgacag tcctcggttt tgctaataag gatgctgtta
    43141 ttttgaaaac ggaattggct cagtatggtc aggtctttgt aacgacagat gatggttctt
    43201 atggcatcaa gggaaatgtt tccgttgtta tcaatgattt agatagtcag tttgatgctg
    43261 tttactcgtg tggggctcca ggaatgatga agtatatcaa tcaaaccttt gatgatcacc
    43321 caagagccta tttatctctg gaatctcgta tggcttgtgg gatgggagct tgctatgcct
    43381 gtgttctaaa agtaccagaa aacgagacgg tcagccaacg cgtctgtgaa gatggtcctg
    43441 ttttccgcac aggaacagtt gtattataag gagaaaatta tgactacaaa tcgattacaa
    43501 gtttctctac ctggtttgga tttgaaaaat ccgattattc cagcatcagg ctgttttggc
    43561 tttggacaag agtatgccaa gtactatgat ttagaccttt taggttctat tatgatcaag
    43621 gcgacaaccc ttgaaccacg ttttgggaat ccaactccaa gagtggcaga gacgcctgct
    43681 ggtatgctca atgcaattgg cttgcaaaat cctggtttag aggttgtttt ggctgaaaag
    43741 ctaccttggc tggaaagaga atatccaaat cttcctatta ttgccaatgt agctggtttt
    43801 tcaaaacaag agtatgcagc tgtttctcat gggatttcca aggcaactaa tgtaaaagct
    43861 atcgagctca atatttcttg tcccaatgtt gaccactgta atcatggact tttgattggt
    43921 caagatccag atttggctta tgatgtggtg aaagcagctg tggaagcctc agaagtgcca
    43981 gtttatgtca aattaacccc gagtgtgacc gatatcgtta ctgtcgcaaa agctgcagaa
    44041 gatgcgggag caagtggctt gaccatgatc aatactctgg ttggaatgcg ctttgacctc
    44101 aaaaccagaa aaccaatctt ggccaatgga acaggtggaa tgtcaggtcc agcagtcttt
    44161 ccagtagccc tcaaactcat ccgccaagta gcccaaacaa cagacctgcc tatcattgga
    44221 atggggggag tggattcggc tgaagctgcc ctagaaatgt atctggctgg ggcatctgct
    44281 atcggagttg gaacagctaa ctttaccaat ccttatgcct gccctgacat catcgaaaat
    44341 ttaccaaaag tcatggataa atacggtatt agcagtctgg aagaactccg tcaggaagta
    44401 aaagagtctc tgaggtaaac tgcaatcaat ctgttcttga ttttttatta gtttgtaata
    44461 tgaatttagg agaattttgg tacaataaaa taaataagaa cagaggaaga aggttaatga
    44521 agaaagtaag atttattttt ttagctctgc tatttttctt agctagtcca gagggtgcaa
    44581 tggctagtga tggtacttgg caaggaaaac agtatctgaa agaagatggc agtcaagcag
    44641 cgaatgagtg ggtttttgat actcattatc aatcttggtt ctatataaaa gcagatgcta
    44701 actatgctga aaatgaatgg ctaaagcaag gtgacgacta tttttacctc aaatctggtg
    44761 gctatatggc caaatcagaa tgggtagaag acaagggagc cttttattat cttgaccaag
    44821 atggaaagat gaaaagaaat gcttgggtag gaacttccta tgttggtgca acaggtgcca
    44881 aagtaataga agactgggtc tatgattctc aatacgatgc ttggttttat atcaaagcag
    44941 atggacagca cgcagagaaa gaatggctcc aaattaaagg gaaggattat tatttcaaat
    45001 ccggtggtta tctactgaca agtcagtgga ttaatcaagc ttatgtgaat gctagtggtg
    45061 tcaaagtaca gcaaggttgg ctttttgaca aacaatacca atcttggttt tacatcaaag
    45121 aaaatggaaa ctatgctgat aaagaatgga ttttcgagaa tggtcactat tattatctaa
    45181 aatccggtgg ctacatggca gccaatgaat ggatttggga taaggaatct tggttttacc
    45241 tcaagtttga tggcaaaatg gctgaaaaag aatgggtcta cgattctcat agtcaagcct
    45301 ggtattactt caaatccggt ggttacatga cagccaatga atggatttgg gataaggaat
    45361 cttggtttta tctcaaatct gatgggaaaa tagctgaaaa agaatgggtc tacgattctc
    45421 atagtcaagc ttggtactac ttcaaatccg gtggttacat gacagccaat gaatggattt
    45481 gggataagga atcttggttt tacctcaagt ctgatggcaa aatggctgaa aaagaatggg
    45541 tctacgattc tcatagtcaa gcctggtact acttcaaatc tggtggctac atggcgaaaa
    45601 atgagacagt agatggttat cagcttggaa gcgatggtaa atggcttgga ggaaaagcta
    45661 caaatgaaaa tgctgcttac tatcaagtag tgcctgttac agccaatgtt tatgattcag
    45721 atggtgaaaa gctttcctat atatcgcaag gtagtgtcgt atggctagat aaggatagaa
    45781 aaagtgatga caagcgcttg gctattacta tttctggttt gtcaggctat atgaaaacag
    45841 aagatttaca agcgctagat gctagtaagg actttatccc ttattatgag agtgatggcc
    45901 accgttttta tcactatgtg gctcagaatg ctagtatccc agtagcttct catctttctg
    45961 atatggaagt aggcaagaaa tattattcga cagatggcct gcattttgat ggttttaagc
    46021 ttgagaatcc cttccttttc aaagatttaa cagaggctac aaactacagt gctgaagaat
    46081 tggataaggt atttagtttg ctaaacatta acaatagcct tttggagaac aagggcgcta
    46141 cttttaagga agccgaagaa cattaccata tcaatgccct ttatctcctt gcccatagtg
    46201 ccctagaaag taactgggga agaagtaaaa ttgccaaaga taagaataat ttctttggca
    46261 ttacagccta tgatacgacc ccttaccttt ctgctaagac atttgatgat gtggataagg
    46321 gaattttagg tgcaaccaag tggattaagg aaaattatat cgatagggga agaactttcc
    46381 ttggaaacaa ggcttctggt atgaatgtgg aatatgcttc agacccttat tggggcgaaa
    46441 aaattgctag tgtgatgatg aaaatcaatg agaagctagg tggcaaagat tagtactata
    46501 agtgaatatg atttgagtga atagtaagtt aaaaatcctg atttcaagta aaatcaggat
    46561 tttttcatgg atgcaatttt tttggagtct ggtgtgacgc ggagggtctt ttgtcctgtg
    46621 taagtgacaa agccgggttt tccaccagtt ggtttattga gttttttgac ttcaatcata
    46681 tctacctgca ccagattcga caggcgccct tgagagaagt aggcagctaa ctctgctgcg
    46741 tctgtcttga ctgcatcaga tgggtcaaga tttcctgaga tgacaacatg gcttccagga
    46801 atgtccttag catggaacca aagttcctcc ttgcgggcca ttttaaaggt caattcctca
    46861 ttttgaagat tgtttcgtcc gacatagatg atggttttgc catcgcttgc tagatattgt
    46921 tctagttttt tgcgtttctg gattttctcc cgttgtcttc tgcggataaa acctgtttga
    46981 atcaattctt cacggatttc agcgatttct tccagtccag cttggttgag gacggtttct
    47041 acactttcca gatagagaat agtggctttg gtttcttcaa tcaaatcagt caagtatttg
    47101 acagcttctt tgagtttctg ataccgttta aaatagcgtt gggcattctg gttgggagtc
    47161 agagccttat caagcgcaat catgataggt tggttggtat agtagttgtc taggataacc
    47221 tggtcttggt cgttaggcac ttggtggagg aaggttgtca gcaattctcc tttttgacga
    47281 aattcttcag cgttgtctgt cgccagtaac tctttttcct gttttttgag tttgtgtcgg
    47341 tttttctgaa gttcattttc aacacgacga atcagttcac tggcctgctg tttgacgcgg
    47401 tcgcgctcag ccttattctt atagtaggtg tccaacaaat cagaaagatt tgcaaaaggc
    47461 tctcccgcct gatttgcaaa aggaactgga ctgaaggaag tctcagtcaa gcatggcttg
    47521 gtttcttgat tgaaaaaatt tcggaaagcg gaaagttttt cactaaccag tatcctttcc
    47581 aattcatttg ccgtatcgcg tcccagacct tgaaagaggc tttgaagatt ttttgctgtt
    47641 agttcttggg tttgtaggat ttcaaagagc ttttcatcct tgatagtaaa aggattgaga
    47701 gattctgtac ttggcggagc gatataggtc gatcctggaa gtaaggtgcg gtagctattt
    47761 tgtgaaaaac cgacgtgttt gataacttcg aggattttat gactgctttt atcgaccagt
    47821 agaatattac tgtgtttccc cataatttcg ataatcaagg tagcctggat atggtctcca
    47881 atctcgtttt tattggaaac tgtcatttcc acaatacggt cattttccac ttgctcaatc
    47941 gactcaatca gggccccctg caaatacttt ctcaaaacca tgataaaggt agaaggttgg
    48001 gctggatttt caaaagtcgt ttgggtcagc tgaatgcgtc caaaaactgg atgggcagaa
    48061 aggagcaggc gatggctttg gcgattgctg cggatttgca agaccaactc ttgttcaaaa
    48121 ggctgattga ttttctggat gcgaccattc actaattcgc ttcgcaattc ctcaactatg
    48181 tggtgtaaaa aaaatccatc aaatgacatc gttctctcct tgtgattgta ttccatagta
    48241 ttatatcaaa aaggtagaat aaaatcatgg aaatgtggta taataaagcc aagtaaagag
    48301 aaacgagaag cacatgtata ttgaaatggt agatgaaact ggtcaagttt caaaagaaat
    48361 gttgcaacaa acccaagaaa ttttggaatt tgcagcccaa aaattaggaa aagaagacaa
    48421 ggagatggca gtcacttttg tgaccaatga gcgtagtcat gaacttaatc tggagtaccg
    48481 tgacaccgac cgtccgacag atgtcatcag ccttgagtat aaaccagaat tggaaattgc
    48541 ctttgacgaa gaggatttgc ttgaaaatcc agaattggca gagatgatgt ctgagtttga
    48601 tgcctatatt ggggaattgt tcatctctat cgataaggct catgagcagg ccgaagaata
    48661 tggtcacagc tttgagcgtg agatgggctt cttggcagta cacggctttt tacatattaa
    48721 cggctatgat cactacactc cggaagaaga agcggagatg ttcggtttac aagaagaaat
    48781 tttgacagcc tatggactca caagacaata aacgaaaatg gaaaaatcgt gacctgatat
    48841 ccagtttaga atttgccatc acagggattt ttactgctat caaggaagaa cgaaatatgc
    48901 gaaaacatgc agtgacggct ctagtggtca tccttgcagg ttttgttttt caggtgtcac
    48961 gaatcgaatg gctctttctc ctattgagca ttttcttggt agtagccttt gagattatca
    49021 actctgctat tgaaaatatg gtggatttgg ccagtcacta tcacttttcc atgctggcta
    49081 aaaatgccaa ggatatggcg gctggcgcgg tattagtggt ttctcttttc gcagccttaa
    49141 caggtgcatt gatttttctc ccacgaatct gggatttatt attttaaaca gtaagaggaa
    49201 attatgactt ttaaatcagg ctttgtagcc attttaggac gtcccaatgt tgggaagtca
    49261 acctttttaa atcacgttat ggggcaaaag attgccatca tgagtgacaa ggcgcagaca
    49321 acgcgcaata aaatcatggg aatttacacg actgataagg agcaaattgt ctttatcgac
    49381 acaccaggga ttcacaaacc taaaacagct ctcggagatt tcatggttga gtctgcctac
    49441 agtacccttc gcgaagtgga caccgttctt ttcatggtgc ctgctgatga agcgcgtggt
    49501 aagggggacg atatgattat cgagcgtctc aaggctgcca aggttcctgt gattttggtg
    49561 gtgaataaaa tcgataaggt ccatccagac cagctcttgt ctcagattga tgacttccgt
    49621 aatcaaatgg actttaagga aattgttcca atctcagccc ttcagggaaa taacgtgtct
    49681 cgtctagtgg atattttgag tgaaaatctg gatgaaggtt tccaatattt cccgtctgat
    49741 caaatcacag atcatccaga acgtttctta gtttcagaaa tggttcgcga gaaagtcttg
    49801 cacctaactc gtgaagagat tccgcattct gtagcagtag ttgttgactc tatgaaacga
    49861 gacgaagaga cagacaaggt tcacatccgt gcaaccatca tggtcgagcg cgatagccaa
    49921 aaagggatta tcatcggtaa aggtggcgct atgcttaaga aaatcggtag tatggcccgt
    49981 cgtgatatcg aactcatgct aggagacaag gtcttcctag aaacctgggt caaggtcaag
    50041 aaaaactggc gcgataaaaa gctagatttg gctgactttg gctataatga aagagaatac
    50101 taagtagagg taggctcatg cctgcttctt gtttttacag aaggaggact tatgcctgaa
    50161 ttacctgagg ttgaaaccgt ttgtcgtggc ttagaaaaat tgattatagg aaagaagatt
    50221 tcgagtatag aaattcgcta ccccaagatg attaagacgg atttggaaga gtttcaaagg
    50281 gaattgccta gtcagattat cgagtcaatg ggacgtcgtg gaaaatattt gcttttttat
    50341 ctgacagaca aggtcttgat ttcccatttg cggatggagg gcaagtattt ttactatcca
    50401 gaccaaggac ctgaacgcaa gcatgcccat gttttctttc attttgaaga tggtggcacg
    50461 cttgtttatg aggatgttcg caagtttgga accatggaac tcttggtgcc tgacctttta
    50521 gacgcctact ttatttctaa aaaattaggt cctgaaccaa gcgaacaaga ctttgattta
    50581 caggtctttc aatctgccct tgccaagtcc aaaaagccta tcaaatccca tctcctagac
    50641 cagaccttgg tagctggact tggcaatatc tatgtggatg aggttctctg gcgagctcag
    50701 gttcatccag ctagaccttc ccagactttg acagcagaag aagcgacagc tattcatgac
    50761 caaaccattg ctgttttgag ccaggctgtt gaaaaaggcg gttccaccat tcggacctat
    50821 accaatgcct ttggggaaga tggaagcatg caggattttc atcaggtcta tgataagact
    50881 ggtcaagaat gtgtacgctg tggtaccatc attgagaaaa ttcaactagg tggacgtgga
    50941 acccactttt gtccaaactg tcaaaggagg gactgatgag aaaaatcatc ggaatcactg
    51001 ggggaattgc ctcaggtaag tcaactgtga caaattttct aagacagcaa ggctttcaag
    51061 tagtggatgc cgacgcagtc gtccaccaac tacagaaacc tggtggtcgt ctgtttgagg
    51121 ctctagtaca gcactttggg caagaaatca ttcttgaaaa cggagaactc aatcgccctc
    51181 tcctagctag tctcatcttt tcaaatcctg aagagcaaaa atggtctaag caaattcaag
    51241 gggagattat ccgtgaggaa ctggttactt tgagagaaca gttggctcag acagaagaga
    51301 ttttcttcat ggatattccc ctactttttg agcaggacta cagcgcttgg tttactgaga
    51361 cttggttggt ctatgtggac cgagatgccc aagtagaacg cttaatgaaa agggaccagt
    51421 tgtccaaaga tgaagctgag tctcgtctgg cagcccagtg gcctttagaa aaaaagaaag
    51481 atttggccag ccaggttctt gataataatg gcaatcagaa ccagcttctt aatcaagtgc
    51541 atatccttct tgagggaggt aggcaagatg acagagatta actggaagga taatctgcgc
    51601 attgcctggt ttggtaattt tctgacagga gccagtattt ctttggttgt accttttatg
    51661 cccatcttcg tggaaaatct aggtgtaggg agtgagcaag tcgcttttta tgcaggctta
    51721 gcaatttctg tctctgctat ttccgcggcg ctcttttctc ctatttgggg tattcttgct
    51781 gacaaatacg gccgaaaacc catgatgatt cgggcaggtc ttgctatgac tatcactatg
    51841 ggaggcttgg cctttgtccc aaatatctat tggttaatct ttcttcgttt actaaacggt
    51901 gtatttgcag gttttgttcc taatgcaacg gcactgatag ccagtcaggt tccaaaggag
    51961 aaatcaggct ctgccttagg tactttgtct acaggcgtag ttgcaggtac tctaactggt
    52021 ccctttattg gtggctttat cgcagaatta tttggcattc gtacagtttt cttactggtt
    52081 ggtagttttc tatttttagc tgctattttg actatttgct ttatcaagga agattttcaa
    52141 ccagtagcca aggaaaaggc tattccaaca aaggaattat ttacctcggt taaatatccc
    52201 tatcttttgc tcaatctctt tttaaccagt tttgtcatcc aattttcagc tcaatcgatt
    52261 ggccctattt tggctcttta tgtacgcgac ttagggcaga cagagaatct tctttttgtc
    52321 tctggtttga ttgtgtccag tatgggcttt tccagcatga tgagtgcagg agtcatgggc
    52381 aagctaggtg acaaggtggg caatcatcgt ctcttggttg tcgcccagtt ttattcagtc
    52441 atcatctatc tcctctgtgc caatgcctct agcccccttc aactaggatt ctatcgtttc
    52501 ctctttggat tgggaaccgg tgccttgatt cccggggtta atgccctact cagcaaaatg
    52561 actcccaaag ccggcatttc gagggtcttt gccttcaatc aggtattctt ttatctggga
    52621 ggtgttgttg gtcccatggc aggttctgca gtagcaggtc aatttggcta ccatgctgtc
    52681 ttttatgcga cgagcctttg tgttgccttt agttgtctct ttaacctgat tcaatttcga
    52741 acattattaa aagtaaagga aatctagtgc gagtaaaaat taatctcaaa tgctcctctt
    52801 gtggcagtat caattaccta accagtaaaa attcaaaaac ccatccagac aagattgagg
    52861 ttttaaagta ttgtcccaag gaaagaaaag taaccctaca tcttgaatct aagtagattt
    52921 tatggtaaaa taatagggat tttaaggagt ttgatatgta taacctatta ttaaccattt
    52981 tattagtatt atctgttgtg attgtgattg caattttcat gcaaccaacc aaaaaccaat
    53041 ccagcaatgt atttgatgcc agttcaggtg atttgtttga acgcagtaaa gctcgcggtt
    53101 ttgaagctgt aatgcagcgt ttgacaggga ttttagtctt tttctggcta gccattgcct
    53161 tagcattgac ggtattatca agtagataag aaaataatgg gcaggactag gtctttgcct
    53221 ctttttattt ttaaaggatg tttgagaagg ttttacagta aaagaaaatt aaaaaatcta
    53281 gaaagaaaat atgaaagata gaataaaaga atatttacaa gacaagggaa aggtgactgt
    53341 taatgatttg gctcaggctt tgggaaaaga cagttccaag gattttcgtg agttgattaa
    53401 aaccttgtcc ttaatggaaa gaaagcacca gattcgcttt gaagaagatg gcagtctgac
    53461 cttggaagcc aagaaaaaac atgagattac cctcaagggg atttttcatg cccataaaaa
    53521 tggttttggt tttgtcagcc tagaagggga agaggacgac ctttttgtag ggaaaaatga
    53581 tgtcaactat gctattgatg gtgataccgt cgaggtagtg attaagaaag tcgctgaccg
    53641 caataaggga acagcagcag aagccaaaat tattgatatc ctagaacaca gtttgacaac
    53701 agttgtcggg caaatcgttc tggatcagga aaagcctaag tatgctggct atattcgttc
    53761 aaaaaatcag aaaatcagtc aaccgattta tgttaagaaa ccagccctaa agttagaagg
    53821 aacagaagtt ctcaaggtct ttatcgataa atacccaagc aagaaacatg atttctttgt
    53881 cgcgagtgtt ctcgatgtgg tgggacactc aacggatgtc ggaattgatg ttcttgaggt
    53941 tttggaatca atggacattg tatccgagtt tccagaagct gttgttaagg aagcagaaag
    54001 tgtgcctgat gctccgtctc aaaaggatat ggaaggtcgt ctggatctaa gagatgaaat
    54061 tacctttacc attgacggtg cggatgccaa ggacttggac gatgcagtgc atatcaaggc
    54121 tctgaaaaat ggcaatctgg agcttggggt tcacatcgca gatgtttctt attatgtgac
    54181 cgaggggtct gcccttgaca aggaagccct taaccgtgcg acttctgttt acgtgacaga
    54241 ccgagtggtg ccaatgcttc cagaacgact atcaaatggc atctgctctc tcaatcccca
    54301 agttgaccgc ctgacccagt ctgctattat ggagattgat aaacatggtc gtgtggtcaa
    54361 ctataccatt acacaaacag ttatcaagac cagttttcgt atgacctata gcgatgtcaa
    54421 tgatatccta gctggcgatg aagaaaagag aaaaaaatat cataaaattg taccaagtat
    54481 cgaactcatg gccaagcttc atgaaacttt agaaaacatg cgtgtgaaac gtggagctct
    54541 caattttgat accaatgaag cgaagatttt agtggataaa caaggtaagc ctgttgatat
    54601 cgttcttcgg cagcgtggta ttgccgagcg gattattgag tcttttatgt tgatggctaa
    54661 tgaaacagtt gccgaacatt tcagcaagtt ggatttgcct tttatctatc gaattcacga
    54721 ggagcctaag gctgaaaagg ttcagaagtt tattgattat gcttcgagtt ttggcttgcg
    54781 catttatggg actgccagtg agattagtca ggaggcactt caagacatca tgcgtgctgt
    54841 tgagggagaa ccttatgcag atgtattgtc catgatgctt cttcgctcta tgcagcaggc
    54901 tcgttattcg gagcacaatc acggccacta tggactagct gctgactatt atactcactt
    54961 taccagtcca attcgtcgtt atccagacct tcttgttcac cgtatgattc gagattacgg
    55021 ctgttctaag gaaatagcag agcattttga acaagtgatt ccagagattg cgacccagtc
    55081 ttccaaccgt gaacgtcgtg ccatagaagc tgagcgtgaa gtcgaagcca tgaaaaaggc
    55141 tgagtatatg gaagaatacg tgggtgaaga gtatgatgca gttgtatcaa gtattgtcaa
    55201 attcggtctc tttgtcgaat tgccaaacac agttgaaggc ttgattcaca tcactaatct
    55261 acctgaattt tatcatttca atgagcgtga tttgactctt cgtggagaaa aatcaggtat
    55321 cactttccga gtgggtcagc agatccgtat ccgtgttgaa agagcggata aaatgactgg
    55381 agagattgat ttttcattcg tacctagtga gtttgatgtg attgaaaaag gcttgaaaca
    55441 gtctagtcgt agtggcagag ggcgtggttc aaatcgtcgt tcggataaga aggaagacaa
    55501 gagaaaatta ggacgctcaa atgataagcg taagcattca caaaaagaca agaagaaaaa
    55561 aggaaagaaa cctttttaca aggaagtagc taagaaagga gccaagcatg gcaaagggcg
    55621 agggaaaggt cgtcgcacaa aataaaaagg cacgccacga ctatacaatc gtagatacgc
    55681 tagaggcagg gatggtcctg actggaactg aaatcaagag tgtacgagct gctcgaatta
    55741 atctcaagga tggctttgct caagtgaaaa atggagaagt ttggctgagc aatgttcata
    55801 tcgcgcctta cgaagagggc aatatctgga accaggaacc agaacgtcgt cgtaaactcc
    55861 tgctccataa aaagcaaatt caaaaattgg aacaagagac caaagggaca ggaatgacct
    55921 tagttcccct taaggtctat ataaaagatg gctacgctaa gcttctttta ggacttgcca
    55981 aagggaagca tgactatgac aaacgggagt ctatcaaacg tcgtgagcaa aatcgagata
    56041 tcgcgcgtgt gatgaaagct gttaatcagc gataaaaaga ggaattgaaa atggaaaaat
    56101 tagttgccta taaacgcatg cctttgtgga ataaacaaac aatgcctgaa gctgttcagc
    56161 aaaagcacaa tacaaaagtt gggacttggg ggaaaattac tgtcttgaag ggagctctca
    56221 agtttattga attgacagaa gaaggggaag ttctagctga acacctcttt gaagcagggg
    56281 cagacaatcc aatggcccaa cctcaagcct ggcaccgagt ggaagctgcc acagatgatg
    56341 tggaatggta cttggaattt tattgtaaac ctgaggatta ttttgctaaa aaatacaata
    56401 ccaatcctgt tcattcagag gtcctagagg ccatgcagac agtgaaacaa gggaaagctt
    56461 tggatttggg ttgtggtcag gggcgtaatt ctctttttct agcccagcaa gattttgatg
    56521 tgacggctgt agatcaaaat ggactggctc ttgaaatctt gcaaagcatt gtggagcagg
    56581 aagatttgga catgcctgtt ggcctttacg atatcaattc agctagcatt ggacaagaat
    56641 atgattttat cgtttcaaca gttgttctca tgtttctaca agcggaccgc attccagcta
    56701 ttattcaaaa tatgcaggag aaaaccagtg ttggtggtta caaccttatc gtttgtgcca
    56761 tggacacgga ggattatcct tgctcggtta atttcccatt cacctttaaa gaaggagaac
    56821 tggcagacta ttacaaggat tgggaattgg ttaagtacaa tgaaaatcca ggccatttgc
    56881 atcgtcgcga tgagaatggc aatcgtattc aactacgctt tgcgacctta ctagctaaga
    56941 aaatcaagta aacacacatg aagattagga attttcctga tcttttttct tttttacgaa
    57001 tgatatagaa aaggagggaa ttcatgtttg ttgcgagaga tgctagggga gaattggtaa
    57061 atgtgttaga ggataaactt gagaagcaag catacacctg cccagcttgt ggaggccagc
    57121 tccatttgcg tcaaggacca agtgtacgga cgcattttgc ccataaatcc ttaaaagact
    57181 gtgatttttt ctttgaaaat gaaagtccag aacacctggc caataaggaa tccctctatc
    57241 actggttgaa aaaagagaca aaggttcaat tagagtaccc gctttcagaa cttaaacaga
    57301 ttgcggatgt atttgtaaat ggcaatctag ctctagaagt tcagtgtagt cccttgcctc
    57361 agaaagtcct taaagagcga agtgagggat atcgtagtca gggttaccaa gtactgtggt
    57421 tgctgggtca aaaactgtgg ctcaaggagc gtttgactcg tctacagcaa ggttttcttt
    57481 atttcagtca aaacatgggc ttttatgttt gggaattaga caaggaaaaa caagttttaa
    57541 gactcaaata cctgatttac caggatctcc gcggtaaact ccattatcaa atcaaggaat
    57601 tttcctatgg tcaaggtagt ttattggaaa tattgcgtct tccctataag agacaaaaaa
    57661 tatctcattt tacagtttct gaggacaagg acatctgtcg ctatatccgg caacaacttt
    57721 attatcaaaa tctcttttgg atgaaagaac aagcagaagc ctatcaaaag ggagaaaata
    57781 tcctgactta tggactgaaa gaatggtatc cacaaattcg accaatagtg ggcaaatttt
    57841 tccagattga acaagacttg actagctatt atcagtactt ttatacctat taccaaaaaa
    57901 atcctcaaaa tgattggcaa aagctttatc caccagcctt ttatcagcaa tatttcttga
    57961 aaaatatggt agaataaaaa ggatggagga atctaatggt attacaaaga aatgaaataa
    58021 atgaaaaaga tacatgggat ctatcaacga tctacccaac tgaccaggct tgggaagaag
    58081 ccttaaaaga tttaacagaa caattggaga cagtagccca gtatgaaggc catctcttgg
    58141 atagtgcgga taacctacta gaaatcactg aattttctct tgaaatggaa cgccagatgg
    58201 agaagcttta cgtttatgct catatgaaga atgaccagga tacacgtgaa gctaagtatc
    58261 aagagtacta tgccaaggcc atgacactct acagccagtt agaccaagcc ttttcattct
    58321 atgatcctga atttatggag attagcgaaa agcagtatgc tgacttttta gaagctcaac
    58381 caaagctgca ggtttatcaa cactattttg acaagctctt gcaaggcaag gatcacgttc
    58441 tttcacaacg tgaagaagaa ttattggctg gagctggaga aatctttggt tcagcaagtg
    58501 aaaccttcgc tatcttggac aatgcggata ttgtgttccc ttatgtccta gacgatgatg
    58561 gtaaagaagt tcagctatct catgggactt acacacgttt gatggagtct aaaaaacgtg
    58621 aggttcgccg tggtgcctat caagctcttt atgcgactta cgaacaattc caacacacct
    58681 atgccaaaac cttgcaaacc aatgttaagg tgcaaaatta ccgtgctaaa gttcgtaact
    58741 acaagagtgc tcgtcatgca gccctcgcag cgaattttgt tccagaaagt gtttatgaca
    58801 atttggtagc agcagttcgc aagcatttgc cactcttata tcgctatctt gagcttcgtt
    58861 caaaaatctt ggggatttca gatctcaaga tgtacgatgt ctacacaccg ctttcatctg
    58921 ttgaatacaa ttttacctac caagaagcct tgaaaaaagc agaagatgct ttggcagtct
    58981 tgggtgagga ttacttgagc cgtgtcaaac gtgccttcag cgagcgttgg attgatgttt
    59041 acgaaaatca aggcaagcgt tcaggtgcct actctggtgg ttcttacgat accaatgcct
    59101 ttatgcttct caactggcag gacaatctgg acaatctctt tactcttgtt catgaaacag
    59161 gtcacagtat gcattcaagc tatactcgtg aaactcagcc ttatgtttac ggagattact
    59221 ctatcttttt ggctgagatt gcctcaacta ccaatgaaaa tatcttgacg gagaaattat
    59281 tggaagaagt ggaagacgac gcaacacgct ttgctattct caataacttc ctagatggtt
    59341 tccgtggaac agttttccgc caaactcaat ttgctgagtt tgaacacgcc attcaccaag
    59401 cagatcaaaa tggggaggtc ttgacaagcg atttcctaaa taaactctac gcagacttga
    59461 accaagagta ttatggtttg agtaaggaag acaatcctga aatccaatac gagtgggctc
    59521 gcattccaca cttctactat aactactatg tatatcaata ttcaactggc tttgcggccg
    59581 cctcagcctt ggctgaaaaa attgtccatg gtagtcaaga agaccgtgac cgctatatcg
    59641 actacctcaa ggcaggtaag tcggactatc cacttaatgt catgagaaaa gctggtgttg
    59701 atatggagaa ggaagactac ctcaacgatg cctttgcagt ctttgaacgc cgtttaaatg
    59761 agtttgaagc ccttgttgaa aaaataggat tggcataaaa tggttgaatc gtatagtaag
    59821 aatgctaacc ataacatgcg tcgtcctgtc gtcaaagaag aaattgtaga cttgatgcgt
    59881 cagcgtcaaa agcaagtcac aggttccttg aaagaattgg aagactttgc ccgcaaggaa
    59941 aatattccta ttattcccca tgaaacggtt gcttatttcc gttttcttat ggaaaccatg
    60001 cagcctaaaa atattctgga aattgggacg gctatcggtt tttcagctct cttgatggct
    60061 gaacatgcgc caaatgctaa gattacaact attgatcgta atccagaaat gattggtttt
    60121 gccaaggaaa attttgccca gtttgacagt cgcaagcaaa tcactctcct agagggagat
    60181 gcggtggatg tcttatctac actgacagag tcttatgatt tcgtctttat ggattctgcc
    60241 aagtctaaat acatcgtctt tctgccagaa atcctcaaac atttggaagt tggtggtgtg
    60301 gttgtcttgg atgatatttt tcaaggtggt gatgttgcca aggatattat ggaagtccgt
    60361 cgtggtcagc gaaccattta tcgaggcctt caaaaattat ttgatgcaac cttagacaat
    60421 ccagaactca ccgcaacatt agtgccttta ggagatggta ttctcatgct tcgtaaaaat
    60481 gtagcagatg ttcaactgtc tgaaagcgaa tgattttcag aaaaatttaa gaaaaaatag
    60541 taaaatagat agagtaacac ttatctcaaa ggagtagaca tgaagaaaaa attattggca
    60601 ggtgccatca cactattatc agtagcaact ttagcagctt gttcgaaagg gtcagaaggg
    60661 gcagacctta tcagcatgaa aggggatgtc atcacagaac atcaatttta tgagcaagtg
    60721 aaaagcaacc cttcagccca acaagtcttg ttaaatatga ccatccaaaa agtttttgaa
    60781 aaacaatatg gctcagagct tgatgataaa gaggttgatg atactattgc cgaagaaaaa
    60841 aaacaatatg gcgaaaacta ccaacgtgtc ttgtcacaag caggtatgac tcttgaaaca
    60901 cgtaaagctc aaattcgtac aagtaaatta gttgagttgg cagttaagaa ggtagcagaa
    60961 gctgaattga cagatgaagc ctataagaaa gcctttgatg agtacactcc agatgtaacg
    61021 gctcaaatca tccgtcttaa taatgaagat aaggccaaag aagttctcga aaaagccaag
    61081 gcagaaggtg ctgattttgc tcaattagcc aaagataatt caactgatga aaaaacaaaa
    61141 gaaaatggtg gagaaattac ctttgattct gcttcaacag aagtacctga gcaagtcaaa
    61201 aaagccgctt tcgctttaga tgtggatggt gtttctgatg tgattacagc aactggcaca
    61261 caagcctaca gtagccaata ttacattgta aaactcacta agaaaacaga aaaatcatct
    61321 aatattgatg actacaaaga aaaattaaaa actgttatct tgactcaaaa acaaaatgat
    61381 tcaacatttg ttcaaagcat tatcggaaaa gaattgcaag cagccaatat caaggttaag
    61441 gaccaagcct tccaaaatat ctttacccaa tatatcggtg gtggagattc aagctcaagc
    61501 agtagtacat caaacgaata gtccaaatca atgagtcagg gaaaaaactc gacttcagga
    61561 aaaaatgaag caaacattcc cacaataaaa cgcatagtac aaggtttgta ctgcccccca
    61621 aaaaagttag acaattaatt tatccgaagg atttagttct gtattgcaca gagctaagtc
    61681 cttttagttt tatcttaatt ctcttattgt tgtaataatc aatatagtct ataatggctt
    61741 gttccaattg attaagtgat ttaaatgttt gctcatagcc ataaaacatt tcggatttta
    61801 aaatgccaaa gaaagattcc atcctaccgt tgtcttggct gtttcctttg cgtgacatag
    61861 atgcttgaat tcccttactc tctaggaagc gatgataaga atcgtgttgg tattgccagc
    61921 cttggtcact atggagaatc gtattctcgt agtgcttctc tttgaatgct gttccaacat
    61981 taacgatcaa tcaatttaat catgtaccta agattagaat tgtttatccc aaatttattt
    62041 gaaagcttct ctaagctata tccttgtttt ctaagttcat agatctgaac tttatcatca
    62101 taagttaatt tcataataaa aacaccccaa aagttagatt ttttctgtct aacttttggg
    62161 gtgtagttca tgtacacctg atatgatgcg ttttataatt ttaaagactt tttgaccagc
    62221 ctcatttttt aacttgatac tcagtgaaaa gcaaagatta aactaggaag ctagctgtag
    62281 gctgctcaaa gaacagcttt gaggttgcag ataaaacttg tgaggtaacc aacatatata
    62341 atgtgaagct gacgtggttt gaatagattt tagaagggta tgagtctgga agttttaatg
    62401 gataatgcaa gattccatag aatgggtaag ctagagttct tatgtgaaga gtttgggcat
    62461 aaacttttac cttttcctcc ctactcatct tagtatagaa aagtgaatct aaaatagtac
    62521 ataactgctt ctaaaacatt cttataaatt gatttaaatt ctcaaatcat attattcagt
    62581 tcttatttca ttttgctcta caatcctgtt gagaagacac gtgttcatat caaaaaggta
    62641 ttggcaagtt gcaatacctt tttacaaggt tcttttgtct tatttttgtt tcaactgact
    62701 atatctccta tggttctagt tcagaaggct aggctataat tatgattgat aagaagtatc
    62761 attccaagta ttgagagtga atgtttcaaa atcatgggtt tctataatgg tcaggctggc
    62821 atttgctaga ccgccatctt tacgaagaag tggttcttta tagcctagga gagtacgaag
    62881 actggcagta agattggcgc cgtgtccgac aattagaata cgctcagctg gactatcttt
    62941 taatgatttg ataaattgga tggtccgctg agttgtacta tagagggatt cggctccgaa
    63001 cattcgagtg tcaaattgag caagatttga acgaaaagcc tggatttgtt gcgggtaaat
    63061 agcttccagg gttgcaattt tcaaaccttc taacttccca agttgccatt cacggagatt
    63121 aggaacgatt tctaaagaac agggggtatg gagttgactt tggataatct cagcagattt
    63181 gaccgctcga ggtaaatcac ttgaataaat ctgatcaaaa ggaatttcct tgagatactg
    63241 gccaagtcgt tttagggttt caatggatcc aggaagaaga ggagaatcac cgctagcacc
    63301 ttgaaaacga ccttcttggt tccagagggt acgaccgtgg cggacaaagt agagtttcat
    63361 tacttgatgt cctccaaaat atctacaaag tctgccttta caaagctagc caagtcttgt
    63421 ggcgcgacga taatgctgtg tccgacttcg cctgcagaga caatcattcg atccaaatct
    63481 agagcaattt tatcgataaa aatgtgataa ttgtgtttct gacgaattcc gacaggatta
    63541 ttggctccat gaatgtaacc agttgttttt tctaagtcct tttgtggaat catgctcact
    63601 tttttattgc cagaaatttt agctagtttc ttttcagaca agtgctgagt gatagggaca
    63661 attccgataa tcggtccggt cttgtctccc aaaagcgcca aggttttgaa aatctgatct
    63721 cgttcataac cttgaggaag ctctccttct agggcattga tttgaatccc ctgatgaggg
    63781 atagctgctt tagataggat ttgttccacc aatgtttttt tgattttaac tttttttgcc
    63841 attatttata tttatcctcc aattgactca tccaaatacc aagccagatt cccagcgcaa
    63901 agaagaaggc gatgatgaca taaccgacaa gtgaaagtcc tgtgtattgg atactttcag
    63961 cgtttcctgc atttggaatt aagatcaaaa gggtacttga taggacgata ccgatgatga
    64021 aatgatagac gcgtgagtgg tagttgttta aggcataatc catcaatttt gaaaaaacga
    64081 tgagagttgc acctgcacca attccaatcg gaaagaaggt tcccaagaga tcaaaagttt
    64141 taaaaccagt caacatagga gcatagagtc ccaaaatcaa aagtaaattc gatgggctga
    64201 ggccaggaac caagacgcca agggccaata gtgcgcctgc taggacgaag ttaagaaagc
    64261 tggcgcttaa ggttccaacg acaaaattta aggcatagag tcctaatcca gaaatgataa
    64321 aggttgtcca taaccaagct aaatcaatct tgtctcggtc agattctcga gttgattctt
    64381 tgaggaggct aggaactgta ccgataatag ctcccgcaaa gctccataat acaaagacct
    64441 gataattttc aagcaggtat tcaatcgggt aggaaaataa gccgattccc agaagcatac
    64501 cgatggcaac tggaataaag tacaaaacat tttctttaag gtctttaaag ggatgggcca
    64561 gaaagccaat cattcgttca tagattccta agattgctgc tagaacccct ccggaaattc
    64621 ctggtaggat aaatccaaga gcaattacaa tccctttaat aacgcgtgct aaccatgaga
    64681 gcatatattt cctccaacta tttctatttc aaaaaatcct tactatattg tatcacaatc
    64741 agacacaaaa agaaaaagca aatgataaac aaatgctttt aaggttttaa aaaaagtttt
    64801 cgaaaggttt cttctttatt ttttaaggga gagataacgt tgatatctaa atcgtggtca
    64861 aagccggcaa tttttccttt agatgtgtat tggtgaatat cataatctaa atcagtttta
    64921 ggactgctct ccaaaaatcc tgagtctgag ccgtaggacg gaatccaaac agaggtaaac
    64981 ttgcctgtat caatactgtg ttcttccatg aagtagacac caacgtagat gccgatgttt
    65041 ttagcaccta gtgatgctag ttttgctcga aagttttcga caccttcgtt catattagac
    65101 atggttttgt cttccacgtc aagccaatag taactagggc tgtaaggaga ggcagcattg
    65161 tagaaaactt cggcagcctt ttccatttct tgggcacttt ttccagctac ataagcgtag
    65221 acagcaactg ggacattccg cttttgaagt tcagtgatat gactcttata ggccttgtct
    65281 attccattga taaatgaagc atcattttct tttgtcgttt gagcaccact gtgaacacga
    65341 acaatagcac ctgaaatatt ttgtgagagg gcatcgtagt tgatttcctc aggacgctgc
    65401 cagccagaga ggtcaataat cggtttgtct aagtgtttca aagcctgtgc ttcaatctgt
    65461 gctatattgg attttgtttt aaacgattgg ctgtcattaa gtgggcgatt gatgattaaa
    65521 atgaacatca taatccccaa aaaactaaat aaaataagtg gatgaatttg ttttctcata
    65581 tcttataatt ctaccctaaa aatcaaaaaa aatcaaaaaa atgggttaag gaagagactt
    65641 tagagcattt tttcattcaa gagtgcggaa tgatttgaaa tatggtataa taaaagggaa
    65701 tttctacaga aaagagaaga ttatgtcaaa ttttgccatt attttagcag cgggtaaagg
    65761 gactcgcatg aaatctgatt tgccaaaagt tttgcacaag gttgcgggta tttctatgtt
    65821 ggaacatgtt ttccgtagtg tgggagctat ccaacctgaa aagacagtaa cagttgtagg
    65881 acacaaggca gaattggttg aggaggtctt ggctggacag acagaatttg tgactcaatc
    65941 tgaacagttg ggaactggtc atgcagttat gatgacagag cctatcttag aaggtttgtc
    66001 aggacacacc ttggtcattg caggagatac tcctttaatc actggtgaaa gcttgaaaaa
    66061 cttgattgat ttccatatca atcataaaaa tgtggccact atcttgactg ctgaaacgga
    66121 taatcctttt ggctatggac gaattgttcg taatgacaat gctgaggttc ttcgtattgt
    66181 tgagcagaag gatgctacag attttgaaaa gcaaatcaag gaaatcaaca ctggaacata
    66241 cgtctttgac aacgagcgtt tgtttgaggc tttgaaaaat atcaatacca ataacgctca
    66301 aggcgaatac tatattacag acgtcattgg tattttccgt gaaactggtg aaaaagttgg
    66361 cgcttatact ttgaaagatt ttgatgaaag tcttggggta aatgaccgtg tggcgcttgc
    66421 gacagctgag tcagttatgc gtcgtcgcat caatcataaa cacatggtca acggtgttag
    66481 ctttgtcaat ccagaagcaa cttatatcga tattgatgtt gagattgctc cggaagttca
    66541 aatcgaagcc aatgttacct tgaaagggca aacgaaaatt ggtgctgaga ctgttttgac
    66601 aaacggtact tatgtagtgg acagcactat cggagcagga gcggtcatta ccaattctat
    66661 gattgaggaa agtagtgttg cagacggtgt gacagtcggt ccttatgctc acattcgtcc
    66721 aaattcaagt ctgggtgccc aagttcatat tggtaacttt gttgaggtga aaggatcttc
    66781 aatcggtgag aataccaagg ctggtcattt gacttatatc ggaaactgtg aagtgggaag
    66841 caacgttaat ttcggtgctg gaactattac agtcaattat gacggcaaaa acaaatacaa
    66901 gacagtcatt ggagacaatg tctttgttgg ttcaaattca accattattg caccagtaga
    66961 acttggtgac aattccctcg ttggtgctgg ttcaactatt actaaagacg tgccagcaga
    67021 tgctattgct attggtcgcg gtcgtcagat caataaagac gaatatgcaa cacgtcttcc
    67081 tcatcatcct aagaaccagt aggagcctat catggagttt gaagaaaaaa cgcttagccg
    67141 aaaagaaatc tatcaaggac caatatttaa actggtccaa gatcaggttg aattaccaga
    67201 aggcaaggga actgcccaac gggatttgat tttccacaat ggggctgtct gtgttttagc
    67261 agtaacggat gaacaaaaac ttatcttggt caagcagtac cgcaaagcta tcgaggctgt
    67321 ctcttacgaa attccagccg gaaaattgga agtaggagaa aacacagccc ctgtggcagc
    67381 tgcccttcgt gaattagagg aagaaacagc ctatacaggg aaattagaac tcttgtacga
    67441 tttttattca gctattggct tttgtaatga gaagttaaaa ctatatttag caagcgattt
    67501 gacaaaagtg gaaaatccgc gtccgcagga tgaggatgaa accttggaag tccttgaagt
    67561 gagcttagaa gaagcgaaag aattaatcca atcaggtcat atttgtgatg ccaagacaat
    67621 tatggctgtt cagtattggg agttgaagaa aaaatagagg aggtcagtat gggtaaatct
    67681 ttattaacgg atgaaatgat tgaaagagct aatagaggcg aaaaaatttc aggtcctcct
    67741 ttgctagatg ataatgagga gactaagatt ttaccaacct cttcttcccg ttttggttat
    67801 gccaatccta agaatcatgg ttttagccag gaaaccttga agattcaggt cgaaccatct
    67861 attcataaaa gccgtcgcat tgaaaatacc aagagaaatg tcttcaattc taagttgaat
    67921 aaaatcttat tcgcggtcat ctttctcttg attttgcttg ttttagcaat gaaacttttg
    67981 taatagaaaa ggaattgaaa tgaaaatagg aattattgct gctatgccag aagaactggc
    68041 ttatctggtc cagcatttag ataatgccca ggagcaagtt gtttgtggga atacctatca
    68101 tacaggaacc attgcttctc atgaagtcgt tcttgtagaa agtggaattg gtaaggtcat
    68161 gtctgctatg agtgtggcga ttttggctga tcatttccag gtggatgccc ttattaatac
    68221 gggttcagct ggggcagtag cagaaggtat cgctgttggg gatgtcgtga ttgctgacaa
    68281 attagcctat catgacgtgg atgtcacagc ttttggctat gcttatggac aaatggcgca
    68341 acaaccgctt tatttcgaat cagacaaaac ctttgttgct caaatccaag agagtttatc
    68401 tcaattggac caaaactggc atcttggttt gattgctaca ggagatagtt ttgttgcagg
    68461 aaatgacaag atagaagcga ttaagtccca tttcccagaa gttttagccg tggagatgga
    68521 gggggcagct attgctcaag cagcgcatgc cctcaatctc ccagtcttag tcatcagagc
    68581 tatgagtgac aatgccaacc atgaagcaaa catctttttt gatgagttta ttatcgaagc
    68641 tggacgtcgc tctgcccaag tcttgttgac ctttttgaag gctttagatt aagcggaaat
    68701 ttgacagttt ttctagctta tgataagatt taagtaaaga aaagctagaa aacgtttcag
    68761 aggatattat gagtattgaa atgaccgtca gtgagattgc agaggtctta ggattatctc
    68821 gccaagcaat caataaccgt gtcaaagaat taccagaaga agacacagat aaaaatgaca
    68881 aaggggtaac agttgttacc agaagtggct tgattaagct agaagaaatc tataaaaaaa
    68941 cgatttttga agatgaacct gtcagtgaag atgtcaaaca acgtgaactg atggagattc
    69001 tagtggatga gaagaatgca gaaattcttc gtctttatga acaattaaaa gccaaggatc
    69061 gtcagttatc agaaaaagac gagcagatgc gtatcaaaga ccgtcagatt gctgagaaag
    69121 acaaacaatt agatcagcaa caacaattga cccttcaagc catgaaggat caagaaaatc
    69181 ttaagctaga gctggaccaa gcaaaagaag aagtccaatc cactaaaaaa ggcttttttg
    69241 ctcgtttatt tggaggataa tcaaggagct gtttaggtta aatgctaacc tgatggcttc
    69301 ttttgtttgt gaatagtata gttgattaga acagagacag tagaggagag gtacagaatg
    69361 gaacgattag aagattacat tgcttttgat ttagaattta atcagcatga aggacaaaca
    69421 cacttgattc aagtatcggc agtgcgtttt agagatggtc gggaaatcga tgcctatgat
    69481 tcctatgttc ataccagcgt ccctctaaaa agctttatca atggtttgac cgggattaca
    69541 gctgagacct taaaagatgc tcctccagtt gagaaagtct tagaagaatt ccaagagttt
    69601 gtgggttctt tgctgatgat aggctacaat gctactaaaa gtgatttacc tattttagca
    69661 gagcatggtt tagactatag ccaacagtac aaggtggatt tgtatgatga agcttttgaa
    69721 cgtcggagtt cagatttaca tggtattgcc aatctcaaat tgcaaactgt tgcctcattt
    69781 cttggatttc aaggtcagtc tcataatagt ttagaggatg ctcggatgac ggcgcgtgtt
    69841 tacgaatcct tcttagagtc ggatcaagct agggaattgt tagagacaga aagtagctta
    69901 tctaacaatc cttttggtgg cttggacttg tctcaattat ttgactagga gtgcctatga
    69961 aacctgaaaa acctaaaaaa ttgggtctta aacagattta cctcaatctt gataaaatcc
    70021 tctttctatt tttcttgatt tttatgatag tggagtattt gtgggtacca ttcaattcat
    70081 ggttggctag cttcttatta gatcagacag gttatctttt tatttcctat aacaatgtct
    70141 tagccatcct tactcattct ccattgatta gtctagcttt tttagccttg attgtaatta
    70201 accttctggt tgcttatttt caaataggac tcctctttat tggtgctcgt catctcctct
    70261 ataatgaaaa gcgaaggcta attgagtata tccgcaaggt tttccatgaa agttttggat
    70321 ttatgaaaaa gctaacttgc gctaaagcct tgtttatctt tttctatata gctatgctgt
    70381 ttccttttat acggaaaatg ctgaagattt attatcttaa taaaatcgtc atcccagagt
    70441 ttatccaagc ttatttagaa gataaatatt ggatgtggtg gctgagcatc ctacttctat
    70501 ctcttatctt tctctatgtc tctgtcagat tgatgtttgc ccttccgaag attgtatatg
    70561 atcagctgac tgttcgagaa gcagtgatgt ttagtttgga gaaaaccaag aagagagtta
    70621 ctttttatgc ttggaattta ttttacatct tgctcaaagc acatttatta ttttatcttc
    70681 ctttgcttcc tttattattg gctcaaactt tggtagatga tatcactcag agagagtctc
    70741 tggttcttgg tattttgaat tttgtcgtga ttaaaaatct ctattatatg gctctgactt
    70801 attttttggt taaatttgtt tcatttttga caggaaagga gctggatatg cttcctagga
    70861 gagaaaaaga tcacatcgtg cgatggggtg tcatgacttg tgccagtctt ttctttgcct
    70921 tagaaggtta tatttatctg gaggctccca tggttcatct acctcaactt atttctcacc
    70981 gaggggtttc caatgcaaat gggattcaaa atacagtaga gtccttggaa actacagcac
    71041 aactcaaacc agacttggtg gagacggacg tgcaggaaac aaaagatggg cagtttgtca
    71101 tgatgcatga tgctaacttg aaaaatctag caggtatcaa taaaagtcct caagacttaa
    71161 acttggagga gcttaaaggg attgatattt ttgaaaatgg ctaccagact aaaatttcaa
    71221 gctttgaaga ttatctcagt cgagccaacg aacttggtca aaaattacta attgaaatta
    71281 aaaccagtaa aaaagatagt ccagacatga tgaaccgctt tttagcccgt tatgctgcaa
    71341 agctcaagat ttatggacat caaatccagt ctttagacta ccatgttgtc gaaaaagtaa
    71401 gacagtatga tgccgaactg ccagtttatt tcatcatgcc ctacaattct gtctttccta
    71461 aaacaagagc gacaggatat actatggagt actcaacctt ggatgaatat tttgtaagca
    71521 aactatggac aacggatcag aaactttatg tctggactgt caatgattca gaagctatca
    71581 gcaaatctct tcacttagga gtagatggag tgattacaga tgatttggaa aaagttcagc
    71641 gggaaataga agtagcccaa gaagatccag aatatacgga tttgctcttg aaaaaagcat
    71701 tggaattctt tgaattttag taataaaaaa gaggaacggt tgttcctccc atgataggta
    71761 agtattcttg tgaatgcttg cttttttgtg gttgcaatcc gtttacgaga attgtttgta
    71821 ttgttcttgt ttcaatttac tttatagtgc tttgaagttg gaatgctaca ctataacttc
    71881 taaaatatag taaaatgaac caaaaatagt acacaatgag gtataatctt cttatggcat
    71941 attcaataga ttttcgtaaa aaagttctct cttattgtga gcgaacaggt agtataacag
    72001 aagcatcaca cgttttccaa atctcacgta ataccattta tggctggtta aagctaaaag
    72061 agaaaacagg agagctaaac caccaagtaa aaggaacaaa accaagaaaa gttgatagag
    72121 atagacttaa aaaactatct tactgacaat ccagacgctt atttgactga aatagcttct
    72181 gaatttggct gtcatccaac taccatccac tatgcgctca aagctatggg ctacactcga
    72241 aaa
//
LOCUS       DAVDHC010000010        64357 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVDHC010000010 DAVDHC010000000
VERSION     DAVDHC010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64357
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.010"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..196
                     /locus_tag="VUR43_000882"
     CDS             <1..196
                     /locus_tag="VUR43_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HET5412590.1"
                     /translation="DNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAIIDYIDYYNNK
                     RIKVKLKGLSPVQYRTKSFG"
     gene            412..752
                     /gene="tnpB"
                     /locus_tag="VUR43_000883"
                     /pseudo
     CDS             412..752
                     /gene="tnpB"
                     /locus_tag="VUR43_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(785..1674)
                     /locus_tag="VUR43_000884"
                     /pseudo
     CDS             complement(785..1674)
                     /locus_tag="VUR43_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(2556..4283)
                     /gene="ezrA"
                     /locus_tag="VUR43_000885"
     CDS             complement(2556..4283)
                     /gene="ezrA"
                     /locus_tag="VUR43_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET5412591.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(4365..6311)
                     /gene="gyrB"
                     /locus_tag="VUR43_000886"
     CDS             complement(4365..6311)
                     /gene="gyrB"
                     /locus_tag="VUR43_000886"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET5412592.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(6326..6889)
                     /locus_tag="VUR43_000887"
     CDS             complement(6326..6889)
                     /locus_tag="VUR43_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET5412593.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(6974..7528)
                     /locus_tag="VUR43_000888"
     CDS             complement(6974..7528)
                     /locus_tag="VUR43_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET5412594.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(7539..8762)
                     /locus_tag="VUR43_000889"
     CDS             complement(7539..8762)
                     /locus_tag="VUR43_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET5412595.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(8799..11249)
                     /locus_tag="VUR43_000890"
     CDS             complement(8799..11249)
                     /locus_tag="VUR43_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET5412596.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(11449..12378)
                     /locus_tag="VUR43_000891"
     CDS             complement(11449..12378)
                     /locus_tag="VUR43_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET5412597.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVR"
     gene            12518..12805
                     /locus_tag="VUR43_000892"
     CDS             12518..12805
                     /locus_tag="VUR43_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET5412598.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(12839..14173)
                     /gene="ciaH"
                     /locus_tag="VUR43_000893"
     CDS             complement(12839..14173)
                     /gene="ciaH"
                     /locus_tag="VUR43_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET5412599.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLEDARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(14163..14837)
                     /gene="ciaR"
                     /locus_tag="VUR43_000894"
     CDS             complement(14163..14837)
                     /gene="ciaR"
                     /locus_tag="VUR43_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET5412600.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLLEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(14946..17492)
                     /locus_tag="VUR43_000895"
     CDS             complement(14946..17492)
                     /locus_tag="VUR43_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET5412601.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(17615..18055)
                     /locus_tag="VUR43_000896"
     CDS             complement(17615..18055)
                     /locus_tag="VUR43_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET5412602.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(18030..18899)
                     /locus_tag="VUR43_000897"
     CDS             complement(18030..18899)
                     /locus_tag="VUR43_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET5412603.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQEFVKDYLDTICSFYLGKEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LLSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(18877..19377)
                     /locus_tag="VUR43_000898"
     CDS             complement(18877..19377)
                     /locus_tag="VUR43_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5412604.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVISYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(19388..20086)
                     /locus_tag="VUR43_000899"
     CDS             complement(19388..20086)
                     /locus_tag="VUR43_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET5412605.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGFQVYGVDQGENPLLEGDF
                     HFLQRDLTLDLEPIFGWCPQVDVLCNTAGVLDDYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(20079..20315)
                     /locus_tag="VUR43_000900"
     CDS             complement(20079..20315)
                     /locus_tag="VUR43_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET5412606.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(20415..21341)
                     /locus_tag="VUR43_000901"
     CDS             complement(20415..21341)
                     /locus_tag="VUR43_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET5412607.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(21416..22231)
                     /locus_tag="VUR43_000902"
     CDS             complement(21416..22231)
                     /locus_tag="VUR43_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412608.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFLLFRGFKKIKWSEV"
     gene            complement(22235..22555)
                     /locus_tag="VUR43_000903"
     CDS             complement(22235..22555)
                     /locus_tag="VUR43_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET5412609.1"
                     /translation="MKETQLLKGVLEGCFLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(22885..24882)
                     /gene="metG"
                     /locus_tag="VUR43_000904"
     CDS             complement(22885..24882)
                     /gene="metG"
                     /locus_tag="VUR43_000904"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET5412610.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQVYVDRMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKDHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEKSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(25006..26265)
                     /locus_tag="VUR43_000905"
     CDS             complement(25006..26265)
                     /locus_tag="VUR43_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5412611.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKFQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(26267..26968)
                     /locus_tag="VUR43_000906"
     CDS             complement(26267..26968)
                     /locus_tag="VUR43_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412612.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(26952..28151)
                     /locus_tag="VUR43_000907"
     CDS             complement(26952..28151)
                     /locus_tag="VUR43_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET5412613.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            28416..29762
                     /gene="gor"
                     /locus_tag="VUR43_000908"
     CDS             28416..29762
                     /gene="gor"
                     /locus_tag="VUR43_000908"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET5412614.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTSSEEFVTMR"
     gene            29959..30495
                     /locus_tag="VUR43_000909"
     CDS             29959..30495
                     /locus_tag="VUR43_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET5412615.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            30550..30630
                     /locus_tag="VUR43_000910"
                     /pseudo
     CDS             30550..30630
                     /locus_tag="VUR43_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30699..30914)
                     /locus_tag="VUR43_000911"
     CDS             complement(30699..30914)
                     /locus_tag="VUR43_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET5412616.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            31012..31332
                     /locus_tag="VUR43_000912"
     CDS             31012..31332
                     /locus_tag="VUR43_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412617.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNK
                     FKKE"
     gene            complement(31362..31700)
                     /locus_tag="VUR43_000913"
     CDS             complement(31362..31700)
                     /locus_tag="VUR43_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412618.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(31712..32431)
                     /gene="trmD"
                     /locus_tag="VUR43_000914"
     CDS             complement(31712..32431)
                     /gene="trmD"
                     /locus_tag="VUR43_000914"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET5412619.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(32421..32939)
                     /gene="rimM"
                     /locus_tag="VUR43_000915"
     CDS             complement(32421..32939)
                     /gene="rimM"
                     /locus_tag="VUR43_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET5412620.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPSKRV
                     DVEILEGLDDED"
     gene            complement(32970..33758)
                     /locus_tag="VUR43_000916"
     CDS             complement(32970..33758)
                     /locus_tag="VUR43_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5412621.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKKLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(34335..34574)
                     /locus_tag="VUR43_000917"
     CDS             complement(34335..34574)
                     /locus_tag="VUR43_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET5412622.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(34594..34866)
                     /gene="rpsP"
                     /locus_tag="VUR43_000918"
     CDS             complement(34594..34866)
                     /gene="rpsP"
                     /locus_tag="VUR43_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET5412623.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            35036..35245
                     /locus_tag="VUR43_000919"
     CDS             35036..35245
                     /locus_tag="VUR43_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412624.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMDL
                     LADDSLAGDIILLWRIQFGTFTTET"
     gene            35724..35936
                     /locus_tag="VUR43_000920"
     CDS             35724..35936
                     /locus_tag="VUR43_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412625.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            36020..36823
                     /locus_tag="VUR43_000921"
     CDS             36020..36823
                     /locus_tag="VUR43_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET5412626.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(36879..38420)
                     /locus_tag="VUR43_000922"
     CDS             complement(36879..38420)
                     /locus_tag="VUR43_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5412627.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(38422..38904)
                     /locus_tag="VUR43_000923"
     CDS             complement(38422..38904)
                     /locus_tag="VUR43_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET5412628.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(38904..39989)
                     /gene="rlmN"
                     /locus_tag="VUR43_000924"
     CDS             complement(38904..39989)
                     /gene="rlmN"
                     /locus_tag="VUR43_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET5412629.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(40010..40540)
                     /locus_tag="VUR43_000925"
     CDS             complement(40010..40540)
                     /locus_tag="VUR43_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET5412630.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(40697..41302)
                     /locus_tag="VUR43_000926"
     CDS             complement(40697..41302)
                     /locus_tag="VUR43_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET5412631.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(41475..42512)
                     /locus_tag="VUR43_000927"
     CDS             complement(41475..42512)
                     /locus_tag="VUR43_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET5412632.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(42546..43481)
                     /locus_tag="VUR43_000928"
     CDS             complement(42546..43481)
                     /locus_tag="VUR43_000928"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET5412633.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(44034..45224)
                     /locus_tag="VUR43_000929"
     CDS             complement(44034..45224)
                     /locus_tag="VUR43_000929"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET5412634.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYANTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAADLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(45601..46944)
                     /locus_tag="VUR43_000930"
     CDS             complement(45601..46944)
                     /locus_tag="VUR43_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5412635.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDIVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(47084..47899)
                     /locus_tag="VUR43_000931"
     CDS             complement(47084..47899)
                     /locus_tag="VUR43_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET5412636.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(47951..50131)
                     /locus_tag="VUR43_000932"
     CDS             complement(47951..50131)
                     /locus_tag="VUR43_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET5412637.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(50417..51343)
                     /locus_tag="VUR43_000933"
     CDS             complement(50417..51343)
                     /locus_tag="VUR43_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5412638.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLRI"
     gene            complement(51336..52028)
                     /gene="ftsE"
                     /locus_tag="VUR43_000934"
     CDS             complement(51336..52028)
                     /gene="ftsE"
                     /locus_tag="VUR43_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET5412639.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(52046..53141)
                     /gene="prfB"
                     /locus_tag="VUR43_000935"
     CDS             complement(join(52046..53068,53070..53141))
                     /gene="prfB"
                     /locus_tag="VUR43_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET5412640.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(53249..53905)
                     /locus_tag="VUR43_000936"
     CDS             complement(53249..53905)
                     /locus_tag="VUR43_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET5412641.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(54212..54922)
                     /locus_tag="VUR43_000937"
     CDS             complement(54212..54922)
                     /locus_tag="VUR43_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412642.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(54922..55686)
                     /locus_tag="VUR43_000938"
     CDS             complement(54922..55686)
                     /locus_tag="VUR43_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412643.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(55686..56642)
                     /locus_tag="VUR43_000939"
     CDS             complement(55686..56642)
                     /locus_tag="VUR43_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET5412644.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(56646..57515)
                     /locus_tag="VUR43_000940"
     CDS             complement(56646..57515)
                     /locus_tag="VUR43_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET5412645.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(57783..58943)
                     /locus_tag="VUR43_000941"
     CDS             complement(57783..58943)
                     /locus_tag="VUR43_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5412646.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(59045..59293)
                     /locus_tag="VUR43_000942"
     CDS             complement(59045..59293)
                     /locus_tag="VUR43_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET5412647.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(59372..59962)
                     /gene="clpP"
                     /locus_tag="VUR43_000943"
     CDS             complement(59372..59962)
                     /gene="clpP"
                     /locus_tag="VUR43_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET5412648.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(60136..60765)
                     /gene="upp"
                     /locus_tag="VUR43_000944"
     CDS             complement(60136..60765)
                     /gene="upp"
                     /locus_tag="VUR43_000944"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET5412649.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(60854..61321)
                     /locus_tag="VUR43_000945"
     CDS             complement(60854..61321)
                     /locus_tag="VUR43_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET5412650.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(61340..61897)
                     /locus_tag="VUR43_000946"
     CDS             complement(61340..61897)
                     /locus_tag="VUR43_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET5412651.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            62022..62867
                     /locus_tag="VUR43_000947"
     CDS             62022..62867
                     /locus_tag="VUR43_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET5412652.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            62926..64098
                     /locus_tag="VUR43_000948"
     CDS             62926..64098
                     /locus_tag="VUR43_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET5412653.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            64113..64352
                     /locus_tag="VUR43_000949"
     CDS             64113..64352
                     /locus_tag="VUR43_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET5412654.1"
                     /translation="MEQSPQKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFL"
BASE COUNT        19115 a        14001 c        11665 g        19576 t
ORIGIN      
        1 agacaacggt atgatggaat ctttctttgg cattttaaaa tccgaaatgt tttatggcta
       61 tgagaaaaca tttaaatcac ttaaccaatt ggaacaagcc attatagact atattgatta
      121 ctacaacaat aaacgaatta aggtaaaact aaaaggactt agccctgtgc aatacagaac
      181 taaatccttc ggataaatta attgtctaac tttttggggg gcagtacact acacctacta
      241 ttatacgttt ttatcatttt gaaatctact gctaatcaat gaagaagcaa agatcaaact
      301 aggcagctag ttacaagtta cgtaagcacg tcataacaag gtatctatcc taattcccca
      361 acttccagta tactagataa aaaataatta tcggaggaaa ggtattgtac tatgataatt
      421 caactaagtg atttaggtca agttcacctt gtttgtagca agatagatat gaggcaggga
      481 atagactcat tagcctatgt agttaaaacc cactttgaat tggatccttt ctccggtcaa
      541 gtctttctct tttgtggtgg acgtaaagac cgctttaaag ccctttactg ggatggtcaa
      601 ggattttggc tactatataa acgctttgag aacggcagac tgacttggcc cagtacagaa
      661 aaggatgtca aagctctcac acctgaacaa gtagactggc ttatgaaggg cttttctatc
      721 actccaaaaa taaatccatc agaaagtcgt gatttctatt gaaatgagga ctttcttttt
      781 atactcatct gctttcaaaa agcattctag tccatctccg attaacgatg ggctttatca
      841 cctccttctc cagtccttgt atgatatctt aaagttgatt catgacatct tccaaagttt
      901 gaaaggcttt attcttaaat ccacgtttac gaatctcttt ccacacttgt tcaatggggt
      961 tcatctctgg tgtgtacgga ggaataaatg caaagccaat attagtcgga atctttaagg
     1021 tacttgattt atgccatata gcattgtcca taacgagtaa aaggataagc ttgtgaaagc
     1081 tcttctaaaa aggcgttcat ccactcagta ttacatccac cagctattaa gaaaaatgat
     1141 tcgcctgtat aggcataaca atagcgaaat tctcgtatat agtgactatg gacatgtgga
     1201 cctactccta ttggagccca acaagatccc agtttactga ttctaccgaa accagcctca
     1261 tcttggtaca tcaagcgaac cttacgaaaa cgtctactgg ttttaaatcg ctttcttttc
     1321 ttcttgaatt gagattttat ttttagacgc gacaatggtt tgagcgtctg ctttcctagg
     1381 atgttctgga cgtggcataa tatttcgcca accatggcgc ttcaacagtt gatagaaggc
     1441 atcacgtgtg taggaacgac ctaactcctt tttataagcc tgaaataagg catcaattgt
     1501 aacaaattct cctgcatctg tagtcttcaa atgacgggca agaaaggctt tctcttgctc
     1561 aatcgtcata tatgcatggt tacgaccacc acgtgtttct tgaaggagag agtcgagtcc
     1621 gaactcctca tattttttta catttcgcca aatcgttgtt tgattacagt ctatagtata
     1681 ttgaatctat aacagtacac cttggctgct aaaatatttc tataaattaa tttgactttc
     1741 ctgatagagt tgttcacatc ttatttcaaa ccactataaa agttctataa tctctttata
     1801 agatttgccc atcagacgaa atatagtaga ttgaaactag aatagtacac ctctacttct
     1861 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tgccctgttc ttgtttcgtt
     1921 ttactataga acgatttgaa ggcgtttatg atatttagct gtacgagagt cttttaaaag
     1981 tgttttgatg gcttggattt cttctttagt tgattttata ttactattat ataatacttt
     2041 tttattttag tctagtataa atagcgagaa atatctatcc tatcttctag aatgtcttcc
     2101 aaacgagaaa actctcgtaa acaaagaggt tttagaggcc tatttaccgt gggactaaag
     2161 ttgtacaaga aaagtgcaaa taagaaatct ccagattagg aactatccgt gagttctcta
     2221 gtctggagat ttttcaatag acttcgttat tggacggtta ccaagttact caaagtacag
     2281 atttgaagct gcagataaga ctgacgaaat cactttaata ctaaatgaaa atcaaaaagc
     2341 aaactaagaa gctagcctca ggctgtactt gagtacggta aggcgacgct gacgtgattt
     2401 gaagagattt tcgaagagta taaaacactg ttttgaggtg gtggataaat cggctgggta
     2461 aaaactcaat ctcaggagaa aatgaagtaa atctccccac aactatagaa aaagatttga
     2521 ttctgctcct cacacaataa aatctttttc ttttattaaa aacgaatcgt ttcacgtgtt
     2581 ttctcatatg aggtaacaaa gcgattggtt acaccaggct ctgccacttc caatgcttga
     2641 gaaatcttgt caaatgaagc gtgataatca aattcttttt caaaaatatc taaagcttcg
     2701 ttaaatgctt cttgaatgcg ttcatcaaat gagcgatagc ggttagaata ttgcaagagt
     2761 tgctctgtca aagttgcata ttgtacaata ttataagttt ccgtttctaa agcttccata
     2821 tcattcgttg caatttcaag aactcgggta acagattcaa tgttaatcat tttttgttct
     2881 aactcaacca ttaaatcctc ggtattattg cttgccgtaa agaataactt caagaaagtt
     2941 tgtggaatac ctggcagatt gcgtttttcc atgtatcgct tgatagtatg gagacgattg
     3001 acataaacat tggccttttg acgtgcatta atatcatctt tctcaatttg tgtcaggcgc
     3061 tcactaactg aaatttgctc atcttcaata tcttttagtt gagtttgtaa atcctcaaga
     3121 ttttcttcaa gaactgaata agcttgggtt ggttcttctt gattcgaagt tacctcaaca
     3181 atagctgcct caaaactctc taattctgtc tgaatacgac gaacatggct tgcagctgtc
     3241 tcaggaagta aataggtctt gttcaaacgt gcaatatctt ctcccaataa agtattattc
     3301 tctttcatat gttgaagata agttggaaga gttgcaagta gattttccac tactttctga
     3361 gcagcaattt ctcgagtaaa aatatcatac aaggcattga tttcctcttg tgcctgtcca
     3421 ttctcatatt cggcattatc caattccaac tgacgaatat tctcttggtt tttcttgaat
     3481 gcttcataaa gcaagtggaa acgcgcttca atatccgttt caacaaaatg ataattagca
     3541 tcaattagtt tacgataacc ggcttccaaa tcctgtaatt gatctggcaa ttctgtagaa
     3601 agcgtcgtaa ccaaggctgg aacacgatcc acaatatgac ttaaggccaa aatgtgattt
     3661 tctgtattat ccaaaatcac tgcggcttcc acagggtcac ccgatgaatt caaggttaca
     3721 aattgtgaaa attcagattg gatattttct aattgttttt caatttcatc caaggcttga
     3781 ccatactgtt ctgaattttc agcaactcta tgctgaagtt cctcaaataa atccaaagca
     3841 tgaagaacac gaccactatt tttagattct tgcttctcta agtctgccaa agcattgcga
     3901 attgccgcaa tatcttcttc aatcaaagta atttgactct caatttggtc aatttgatga
     3961 ctggccttga gaaaacgaaa tgaatggtta tagccttctg cttcaaagag attattttca
     4021 atatcggcaa aagagttgag agataaatcg acccattttt gattccattc acggaaagcc
     4081 acttgacttt gtccaatcaa gtgcatattt tttacagctt ctacttcatc atttactgga
     4141 agattgtata gttcttcttt tctttcttct agcgcctcta atctcccctc gtttcgctta
     4201 cgtagaaaga ttgccactac ataagccaga actaaaatga ctgcaattgc aaccattaaa
     4261 taaattagtt gtccattaga catatcaaac tcctttttta cttgaaacaa tcgtaacgat
     4321 tatatcatat tttttagacc aagggaacta cttctcccta ttttttagac atcaagtgta
     4381 ctatagacag cattttcttc gataaactca cgacgaggct ctactcgatc ccccatcaac
     4441 atatcaaaga ttttatctgc ttctgcagca tcatctacag aaactctagc catcaagcga
     4501 tgttcgggat ccatggttgt ttcccacagc tgatgatcgt ccatttcacc tagcccctta
     4561 taacgctgaa tagtcggttt ggtacgacct tcactataac gggctaaagc ttcttggagt
     4621 ttgatttctt gatctgcacc cggctggata tattctttaa tctcgcttcc aaccttgaca
     4681 ccatagattg gtggttgggc aatataaaca tatccagctt ctaggattgg tttcatataa
     4741 cgataaatca aggttaaaag aagggtacga atgtgggctc catcgacatc ggcatcggtc
     4801 atcaaaacga gtttttggta acgggctttc gaaacatcaa attctgcgcc aaatcctgtt
     4861 cccatggctg tgaaaagact acgaatttct tcgttggcta gaatcttatc catacttgct
     4921 ttttcaacat tcaaaatctt accgcgaatt ggaaggatag cctgaaactc acggttacga
     4981 ccagatttgg ctgatccacc agctgagtct ccttcgacga tgaagagttc tgtttcagca
     5041 gggttattag aagaacagtc tgctagtttc cctggaaggt tggaaatttc caaaccagat
     5101 tttttacgtg tgacttcacg cgcacgcttg gcagccacac gagccttggc agccaaaatt
     5161 cctttttcta cgatacgttt ggcaatctgt ggattttcca tgaggaaatc ggagaaggct
     5221 tcactgaaga ggcgattggt aatcttgacc acttcgctat ttcccaattt ggtcttggtt
     5281 tgtccttcaa actgtggatt tgggtgttta actgagataa ctgcagttaa gccttcgcga
     5341 acatcttccc ctgttaaatt atcttcattg tctttcagta acttattctt acgagcataa
     5401 tcattgataa cacgagtcag tgccgtacgg aaaccttgtt catgcgttcc accttcatgg
     5461 gtatgaatat tattggcgaa actcatgaca ttttcatggt aacctgttgt gtactgcatg
     5521 gctacctcaa ctgtaatatc atccatctca ccgtctgtat agattggtgt atcaaagatt
     5581 acatccttgt tctcgttgat atattcaacg taactagcaa tcccaccttc ataatgataa
     5641 tgcttggttt gttccaaacc ttggcgctta tcagtgatag aaatttgaag accgcgattt
     5701 agaaaggcca actcttgaat ccgtttattt aatttatcaa aatcaaagat tgttgtttca
     5761 gtgaaaattt ctgggtccgg tgtgaagtga accgttgttc cagttctatc tgtatcccca
     5821 accacctcaa ggtctgcaac aacatgacca cgacggtatt cttggtaatg aatcttaccg
     5881 tttttatgga catgaacgtc taattgagtg gaaagggcat taactactga cgaccccacc
     5941 ccgtgaaggc cacctgaaac cttgtatcca ccaccgccga actttcctcc agcatgaagg
     6001 actgtaaaga cggtctcaac agcaggacgg cctgtttttt cctgaatatc gactgggata
     6061 ccacgcccat catccacaac agtaatcgaa tcatctggct caataaaaac ttgaatatgg
     6121 ctggcaaatc ctgccaaggc ctcgtcaatt gagttatcaa caatttccca gactagatgg
     6181 tgaagacctt cttttgaggt tgatccaatg tacatccctg gacgcatacg aacagcctct
     6241 aaaccctcta aaacttgaat ttgactggca tcataatcct gtgcctgcag atttttgatt
     6301 tcttctgtca tcttattcct ttttcttata tgtctaatac ttgtcttaaa ttcacgatac
     6361 tggtaaacaa gtgggtatca agtcctgcag cttgacctgc ttcgatatca atcggccgat
     6421 caccaatgac aagaccagag ctaatctgat acttttctct taaataaagc atggattcgg
     6481 gatttggttt tctcttaaag cctgagctag aagtcaccac ttctgtaaaa taagctgcta
     6541 tagaggtttt ttctaaaatt tccaaaacct gatcatttcg atgagagacc aaaaaatgac
     6601 ggccaccttg atttgaaatg tcttccaata ggtcagaaac tccttcaaat aaaatcgggt
     6661 gttcaagctc tctagcttca ttttccttgt acttttctaa aaaattctct aaattgggag
     6721 cgaatgtctc aatcgcaaaa ggagtagaaa cctttaaagc ttgatagaca ctgtcatggt
     6781 cttgtgtgat accatacagt gccaatgttt caacaaatgc agctgttgaa gtttcataat
     6841 tatccagtaa agttccacct aaatcccaga tgtaatcgtg atatttcata cccttcatta
     6901 tagcattttt ttatgaaaaa agcgatgatt tccctgagtt ttccacataa aaaacgagag
     6961 aataactccc gttttactga tttttaccaa agacatctcg atagagcatt cctgttcgta
     7021 aactctctgc gtcccctcct agttgctcca ccaactcgta ggcaaaggca agggctgttg
     7081 aaggaccccg actggttgtc aactgaccat ctaccactac tgtttccttg acgtagtgac
     7141 catcaaggat ttgctcttga acgccgtcat aacaagtgta tcgcttattt ttcaatatct
     7201 ctgcttgatt gagggcaatt ggtgccgcac aaatggctgc tagtttcttc ccttcttgct
     7261 cgaagctttg caattcttga atcaaggtct gattatcacg taaatgtgca gaaccaggca
     7321 tacctccagg aagaacaatc atatcatagt ctgataaatc tccatcaaag acatgatctg
     7381 ctcttacttg gattgcatgc gaacccgtta cttgctcttc aaaaccaacc atatcacatg
     7441 tgatattggc tcgacgcaag acatctacaa ctgtcaaggc ttcaatttct tcaaagccct
     7501 gagctaacat aactgctact tttaccatga ttttctcctt atttaatttg ttttaataca
     7561 acctttttcc gtttgaatgg gacttttccg ctcttttctt cagctagatt agtctggtaa
     7621 ctcatcgata aaagcaaacc aacaccaatc agattactga taatagctga tcccccttgc
     7681 gaaatgaaag gcaagggaat ccccgtcaaa ggaagtagtc cagtcacagc accgatattc
     7741 tcaaagatgt ggaagagcaa catcataatc aaacctgtgg aaatataagt gtagaactgg
     7801 ttatttgatt taagagtaat cttcaacata cggtaaatca acatgagata gagggcaata
     7861 accaggacag agccaataaa gccaaaatct tctgcaataa ccgtaaaaat catatctgac
     7921 tctcgaactg ggataagcag attcgaagca ttaaatccct gaccaaataa gccaccactc
     7981 ccaatggcaa tctgcccttg agcctgctgg taagtcgttg tttgggcaaa ctcaaaggga
     8041 ttgagccaag ccaaaatccg attgatttgg taggtcggca ttccaatctg gtgaagaaaa
     8101 gctcgtccgt ccttgctaat aaagatagct aagaaaccag caactcctgt tacagcagtc
     8161 acaaatactg ggataataat tttccaagaa acccctgata ataaaacgat tcctgagaaa
     8221 atggctacaa aaaccaaagc cgtccccaag tcactttgaa gtgctaaaag aactaggact
     8281 ggaatggtaa agagaatcat ccagaaaatt aacaaaaagt ccagcggaac cgtgcgtctc
     8341 cattccttat gtttctttgt aaattggaca atgacacgag ccaacatgag gatataggat
     8401 atcttcataa attctgacgg ttggaatagg gtaattccat ttattgatac ccagtttttg
     8461 gcacccgttg atgcaactaa gcttggatta taaaatacaa tcggcaagat cataagtccc
     8521 aagcctaaaa tatatagaaa gggggtcacc ttccaaagaa attctgtatt aaagagcatg
     8581 accacaaaac caatcacaag ccccaaggca atccaggcga cctgctgccc taaaatgggc
     8641 agaatattat tgggataatc atgactaacg gctatataga tagccaccac accgatgacc
     8701 agtagaaaaa atactggcaa gagcaaactg taatcgactc ttgagtcgag agaacgtttc
     8761 atatatacta accttatact ttcatacaat actatttatc aaagttcatt aaaaaatcta
     8821 tcaatagcct cgtcaacttc ggatcgagag atggttttaa cagtcgcttc ttctgctaga
     8881 gatgctacta tttgtttgcc gtatcgtttt ccgacgattc tcctatccaa aataagagtt
     8941 aaggaacgtt ggtattcacg tctcatactt cttcccaaag cctgttttaa acgaataatg
     9001 gccattggca attgataatc ataaaaggca tttttccctt cttgattcag ttcttgatta
     9061 atctttttcg tcaagggttc ttgaggattt tggaaaggaa gcctcggtac aacttgaatc
     9121 acaaaaggat ggcttgaaaa atcaactccc tcccagaaac ttgctgcacc aagcaagatt
     9181 tgttgttcac ctttttcaaa gcgtttcttt agctgatgaa catccccatt tttatactgg
     9241 gccaagtggc taactgtaag taaatccgat actgctagaa gcatgtcttt agcggtaaag
     9301 agaaccaaaa tcggttgctg gaaagcttga atttccacta gtaaagcagc tacctctctg
     9361 gcatagactt ctaaggaggt ttctgttacc agagggaaat ctttgaccat gaccacttct
     9421 tgttcctgtt ttccccgaga ttcaatcttg acaaatttgg cttcaggata gcctaaaagg
     9481 tctgccaaag aaaccctctg actaatctca agagtagccg atactcccaa gacttggcaa
     9541 ctctcaggaa gtaaagagga cagaagagta cggcctgatt ttgtagaaga aatctgaatt
     9601 ttcttttgac tcgtttcagt tacttcaagc cagtaatcac cttcagctgt aaaatagcga
     9661 accagctcat caaagccttc cacttctaat tctgaaaaat actgatggag attgtccaga
     9721 gaatctaaga tatttttcct agatttgcca gactgaaatt gttctatcaa gtagagacac
     9781 tcaaagcgaa tactttctag tatccgttgt tgaaccctgt tttcttctcc tactaaagcc
     9841 ttatcaatta aatcgataat agattgtata tcgtaggtct cttgaagcag attttctaga
     9901 gctaacaaaa tcttttggac ttcatcaata atcagtaaac ggtcactgac aaattcagga
     9961 ttatcttcaa gtctggtcac gagataggca tgattagtca ctaaaagctt gcaagtctct
    10021 gccctttctt gactacgttt ccaaaaatct tccgtcacaa ataagctctg ggatgataaa
    10081 ttcccatcat gacgaaggtc tgctagaaaa tgttggtaac ggtagagttg cccgatttca
    10141 tccaaatctc ctgtctctgt ctcagtaagc cagaccaaga cttgcatttt aaagcgtcta
    10201 aataagcgat tttcatcatt ttcctgcaag gaatgataaa aggcatccaa cttcagataa
    10261 ttttgtggtc cctttaagct atgaatatct gtatggaaca cttccttgag acgtttacct
    10321 tcttcttcca tgatttgatt ttgaagaatc tttgtcggaa cactaagaac aatttgtcgc
    10381 tctttggatt gagataaagc gggtaagaga tagccatagg ttttcccaat ccctgtcggc
    10441 gcttgaatca gagagacagg ttcatctttc aatagcaagc caacctcttt agcaaaactt
    10501 tcttgttcct ccctcacttc aaggttcaac agagaaatat ttttagaaaa gtcttgagat
    10561 agttttcgta gctccagaga agctgccgtt ttcttaaaat acagaccttg aacttggacc
    10621 aagtctggag aactcaggat agattggttg cgataagttt cctcaataac caggtaggac
    10681 tcatatagga gagcgtcagc catttccagc aagcgttcca agagaccttt aggaagctgg
    10741 gtcatctttt cccgtaaaaa aagaagtaat tctgctgtag cttgggcatc tgaaagggct
    10801 gtgtgtgcgt gtttaagagg aattcctaat tctcgacaca aaatcggcaa gctatatttt
    10861 tccagttcag ggaaaaagac ctgggccaat tcgaccgtat caacacgagg gtttcttagc
    10921 tcatagcctt caaaaaataa attttccgcc aagagattag catcaaactg aacattatgg
    10981 gctacaaaaa tcccatcctc caccaagtca aatatttttc tggcaacttg cgaaaaatca
    11041 ggtgcttgcg ccagacgttg gtctgtcaat cctgtcagtt ctttgatatg agcatccaag
    11101 ggttcatgtg gattgacatc cgtcgtatag tgatcgacga tttctccgtc ctcaatcacg
    11161 acaattccca cttggataat tttagcctta ctacctgtgc tagttgcctc taaatccacc
    11221 acaacatagc gattaccaat cgttttcatt ataaaaaatt ataccaaaaa aagggccatt
    11281 tggcacctgc aaacatagga taattttcaa actcaagaac actacttttc ttaaaaatcc
    11341 catcgaatag agcattctag cctgctgatt tttgtaaaat agtgaagaaa tacgaaaaat
    11401 tgagagaaga aatgtttgca tcttccttct ctcaacgaat catgtatttt atctaaccat
    11461 gtcaggatcg tagtcataaa atcctgtatc aaggaaacgg tttttagggt gaagtttacg
    11521 aacttcttca tccagcaaga aggcttgatc atggctaaag ttgccctctt gaatcaaatt
    11581 acgcgcttgg ataaagagtt ttgcaatctc aacaaagttc tgaccaggag tgtagagccc
    11641 ttctagtttc cagcgagtaa agccatgctc caccaattct gttaatttga tcatcaaatc
    11701 aaggtcattg ttggcaaaga tatgggtccc atgattatct tcaaaaatgg aatagtggct
    11761 ctctggatca cttggctcag ccaagaagag gtcacgttta tgcgtctttt catcatcgat
    11821 atgtgtaaag ttatagtagt tttgcaagag tggacgttta gaatgatgga tgacgctagc
    11881 accgtaaacc aaaacttcag caggaatttc caaaatctct ggcattttga aaagttcagc
    11941 tgatggaatt tcacgcgcca aaacagcctc agatgcgcca gccttttgtc cccagaagtt
    12001 aatctgacga ctgctagtta ccatggttga agcatcgtag atggtcttaa atgaataacc
    12061 atcgcggtta actacgtaaa agacgcctgc atccccaatc gtaatatagt ctgtcttgat
    12121 ttcttccaag aagtctaaga aaggcttgat acggtccatc atatcttggt gcatgagagc
    12181 attgaccgca acgagcaatt ccttaccagc atcatgaacc aacttagcga tttcacgtaa
    12241 ttggtcataa ctaaaggtcg ttggcagacg aaggccaaaa tctttctcac cgacatagat
    12301 acggtctacg ccagcttcga gtagttgttc aacttgttca atactttcag cagttgctgt
    12361 aatgacaatc ttttccataa gaaaaattat accacatttc tccaaaatca gccatgcttt
    12421 gaaaatgaaa agggacttta ttctttttgt aacctttctg taataattct ctgccgaaaa
    12481 aatgataaaa taggtatgta ctgttaagga gagaatcatg cccgtaagaa aattacaatc
    12541 ctatgaggta gactatcaag aagaattaaa ccagcagctt cctcattacc aagcttatac
    12601 acctgaagcg caatctgatg ccaatctcaa ggaaatccta ttttttatta atatcgctgt
    12661 tttttgtatc tgtattgcta tctttagttt tatcttttta gcattaaaat tatcaactgc
    12721 tcttgccttt gccgcagcaa tcggattcag cttacttgtt ttaaaagttc aacggtctat
    12781 tatcaaacga aaacgtagaa gatagatcca aaatatcgcc ccaattggag cgatattttt
    12841 attttttctt tttagatggt gtctgaatgg caatcttcac ttcaaagatt gttcccttgg
    12901 gtttattatc tttgacagta acagttcctt ttagagcatc tacaatttgc ttggctaggg
    12961 ataatcctaa accaaaacca cctttttgcc gggttctagc tttgtctact cgataaaaac
    13021 ggtcaaaaat tttcttttta tcttctgtcg aaataccgat tccattatca gaaacaagta
    13081 aataaagatt gcgatcggtc gccgagataa gaaaatcaat ttcaccatcc tcctcagtat
    13141 acttgacggc attatcgaaa agaatggtca tcagttgttt cagaagaagc tgatctgtga
    13201 caattgttcg atggatacga ttttcaaaac ggaagacacg attattttcc gaagcaatca
    13261 tctcgtagtt tgtgaaagtt gtattaaaaa agctagttgg aacttctgca agctccggct
    13321 taatcccatc atctctccga gctaagttca gcaagcttgt cgttaaaaaa cgcatatttc
    13381 ggacttcttc caaactcgat gcaatgcttt cgctcacatc cataatggta gcttctggct
    13441 tacgaaaaag ggtctctaag cgattttgca aaactgcgag tggagttcgt aactcatgac
    13501 tggcattttc cacaaaagac tgttgcttct gcatactctc aagcaggggc ctaacactga
    13561 ccctagctag atagagactg gcaagtaaag acaaaatcca gaaactagcc atcacgacca
    13621 caatcaattg ctcatgcttt tgactagcct gctccaactg actggtatta atcaagacag
    13681 cagcatactt tatattggtt gaaaccgaac taatattggt ctccatcaaa atcacacgat
    13741 agatttcttc ctgcccatag ctattaaaaa cctgaatctg gtagatatgt cctagttctt
    13801 tcttttctaa cttaatctta tccaagccca aaaatcgatt tccagaaaga agttgagtaa
    13861 agtctttatc aaagagaatg acttccgtat tggaactgac attaggtttt atttctactt
    13921 tactagcgtc cgccctagca tcttctaaat ctttaatctc ttctgttgcc ctatttatag
    13981 ccagctgaat aactgcttga ggattttcac tcagtccatg aagcttatcg tccaccgaag
    14041 tataaagact cgaatgcatg acttgtaaaa taatcagagt cattgtagaa aaaatcaggg
    14101 tgaagacacc gaagttacgg ataaaataac taaagtcatc cgcataccat gtttttttaa
    14161 gtttactgaa catcttttaa aagataccca acactacgca aggtttgcaa attctctgca
    14221 aaagtggttc cctttaattt cttacggact tttgaaacat agacttcgac aaccgaaatc
    14281 gttgtatcac tatcaaatcc ccatagacgg tcaaaaatct gcgtcttagg caaaatcaca
    14341 ttttgatttt gaaggaaata aactagtaaa tcgaactctt tccccagcaa ttcgacagga
    14401 gtatcttcaa ctttaacggt attggttgat aaattaacca cgatattccc ataagtcaag
    14461 gtgttttcat taaacttccc tgaacgtttg agaagggcct gaatccgcat tttaagttct
    14521 tctaggtaga aaggtttggt cagataatca tccgctccca gttcaaatcc atgtcccttg
    14581 tcatccaaac tttccttggc agtcataatc agaactggtg tcgtaattcc cttttcacgc
    14641 aattctttta agacttggaa accatttttt tctagcaaca tcaaatccag caaaatcaag
    14701 tcatagacac cactctcagc ttcgtagaga ccttcttctc catcaaatac ctgcataaca
    14761 tccgcaaaat cgtctaaaaa gtcaaatact gaatttgaca gacctaggtc atcctcaacc
    14821 aataagattt ttatcatgag aaactcctcc ttattaaaac tattatacca aatttgcctt
    14881 aaaaaaaact caactctctg cattttacat gagatagctg agttttcttt ttattttagg
    14941 cttatttatg catttccgta ttgaagaaca actgcttcga ctgcagcttt ttcacggcta
    15001 atcaagtcaa cacgtgctgc aatttccttg attcccatac cgatgttacg gctaagagca
    15061 aggtcagaaa gttgcggctc aaagaactcc ttgtattccg ccaagcgttg ctgagtctta
    15121 aatacatgag caggaaggat aacaaagcta tcaaagctca tatctcctcc aagggctgcc
    15181 ttaatccaag cccagttttc acgcgcccaa gaccaagctg ttttctgagt tgcttgatga
    15241 gctaggaatt gataatacca agcagacaag tcctgtggtt tgaccacaaa tttgtccttc
    15301 caagaagtaa tcaagttttg gatattatcc gcatctgtac tgtatgcaag agctgctgcc
    15361 aactggcgtt taaagacagc atctgttgcg tgagtataag tatcaagata aagtgctaac
    15421 aagtctttag tctcatgatg tttcatctca ttaatcagaa cttgtgaacg aatagctgct
    15481 gggagtcctg caagattctc cttgtgtgtt gcgaagattt ggctagcgac ttgactagct
    15541 tctgcatcat ttgagcgaat catcatcgaa acagccagct gacgaaccaa ttcatcctca
    15601 tctgattctc cgtctttagc ttcaaaacca agacggtcat agttatgacg agccaattta
    15661 gcaaccagtc ctttgaaggc tgtttcagca tccgttcctt catcaataaa gcgctcaagg
    15721 gctgaaatca cttgagaaac agctgaaacc accagataag actcttcctt agcaagttta
    15781 tcaagaactg gaagcaagtc tgcataagaa atgtgccctg cctcagccaa caaacgacgt
    15841 tcttgaacaa tttgcagttt gcttgtgtta tcaagtgtct ctagctcagc aagaacagct
    15901 tctaacaagt ctccttgata gtcggtaata tagtgggcag tattttcagt gttgagacga
    15961 agagctcctt cattttcagc aagaagagct gcgtagccag ggatttcgat actttcagtt
    16021 tcgagtgtat caggcaagcc tttccagttg ctattgaggg gcaccaccca gagacggttc
    16081 ttgtcttcgt tctcaccgat gaagaattgt ttttgtgaaa tcttcaagac atcattttca
    16141 actttgacag taagaactgg gtaaccaggc tgttccaacc aagaatccat gaaggctgcg
    16201 acatcacgtc ctgacgcttg accaagggca tcccaaaggt cactaccaat ggtgttgctg
    16261 tattggtgtt tttcaaagta ggcgtgcaaa cctttagcaa aatcagcatc tcctagccaa
    16321 cggcgaagca tgtgcatgag acggcttcct ttggcataga cgatagcgcc gtcaaagagt
    16381 gtattgattt catctggatg tttaacttcg acgtggacag actgaacgcc atcagtagcg
    16441 tcacgttcaa gagcaagagg tactccacct gtttggaaat cttcaaagat attccagctt
    16501 ggttcgatgg tatccacaca gacgtattcc atcatattag cgaaactttc attgagccaa
    16561 aggtcatccc accatttcat agtcacgagg ttcccaaacc attggtgagc caattcatgg
    16621 gccacaacaa gggcaacttg ttgacggcta gcaaatgtag agttctcatc gacaaccaag
    16681 taaacttcac ggtaggtcac aagaccccag ttttccatag caccagctga gaagtcagga
    16741 agggcgatgt ggagagattg aggaattggg tacttaactc catagtaatc ttcgtaaaac
    16801 tcgatagagc gaacagcgat atccagtgag aaatcaagat ttgaaagtgg atgtgctttg
    16861 gttgagtaga cacctaccag ggtaccattt ttagttttag cggtcacccc ttgcaaatca
    16921 ccagcaacaa aggccaacaa gtaagaagac atgcgaggtg ttgtctcaaa cttccagata
    16981 cctgtttcct tacggttttc aacatcgatt tctggcatgt ttgacaaggc caattcacct
    17041 tctgcttggt caaagcgaag agagaggtca aaagttgctt tggcttcagg ctcatccaca
    17101 cacgggaaag cttcacgcgc aaaatggctc tcgaactgag tagacaagac ctccttcttg
    17161 actccatcaa ctgtataata agaagggtaa atccctgtca tgttgtctgt aattttacca
    17221 gaaaaggcaa gaaccaattc aacttgacca gcctcagcca attcgatatg aagggcttca
    17281 ttgtcatggt caactgtaaa tggacgagct tgacctgcaa cttctacaga ggtgatttcc
    17341 aagtcttttt ggtggaggga gatgcggtca ctctgtgctt gaccagtgat ggtcactttc
    17401 ccagaaaaag tcttggtctc acgactcaaa tctaaaaata aatcataatg ttcaggaaca
    17461 aattgcttaa taaaatgttc aactgcttgc atagttttct cctattctaa gtttaagagc
    17521 tgctgctctt cttcaaacaa acttattata tcatattttg cttgagaaaa aaggattgga
    17581 cagcgatttc caaaactttc ttccttctaa tagtctacag tgggtagacc ttgcgaaatt
    17641 cttctaaaac aaccttgctt tcaggtgtaa aagtcagccc tacttcaccc aaacagtctg
    17701 tgaaaaagtc ctcatgaacc tggcgccaat aggcaagtga tttgtctccc tcaccttcct
    17761 taaaggcatg ttgcgcagaa acttgattga agagttcaac agaaaccttt gtaatttcga
    17821 caatgcagac agcctgattt tgactatcta aaatgacatc gaaggtccct acttggggaa
    17881 gtggttcgtc ttctagtaca tagaggtcat aggctgatgc tgttgctgtc ttttctcctt
    17941 taaacaccaa atccgctaaa aggtctggtt caactccaaa agcccaagca tcgatttcat
    18001 ctccgatcaa aggattgatt tgcttgtatt tattccacat ttcttgcggt gtcatgggta
    18061 ctcctttgta attttttact ttcttctttt atgtgtttaa gatgatctgg atggtcaatc
    18121 tctaaatcaa aaatctctgg aatagaactg tagtggataa tgcacttgat acccaactga
    18181 ttcatttttt gtatgaaaga agtattcaga tagcctgcta cagcaaaatt aatcttgttc
    18241 tttcttgctt tatcctgcat atctcttagc atatctaaca ttattggact ttccatatca
    18301 tgccattgac tgtttctcat agtcgcaaaa acaaaggaag tcaaatcatt cattccaact
    18361 acaatctttg aaatgcccgt ttccagtatc ctatccaagt caaaatacgc tgacagtaat
    18421 tcaatcatcg ttccgacttt cccagtaaag ccatactgac gcaatactgt aatagcttgt
    18481 tttaattggt cggcatcatt gacaaaagga aagataagag atagattggg attggtttga
    18541 taaacttctg taacgacatg tgcttcagcc tgaaattcat ccaaacacgc cagtaaacgc
    18601 ctggttcctc tatagccaaa caagggatgc ccttcgtcaa aaaactctct agtccccact
    18661 aaacaattgg cttctgtatt cgttaattca gaaaaacgat accaaacttc cttacctaag
    18721 taaaaggagc aaatagtatc aagataatct ttcacaaatt cctgacaact tgctaatatg
    18781 atgttttgat taagctctct caacaaatat tccccacgaa tcatgccgac gtggtgaaat
    18841 agttgaggat aaattttttc aagaattttt tcgccactaa gggcaagttg atttctcatc
    18901 attcaccttc caattcatgt aagaagtctt gtccagttct ggaaatccta ataattcaga
    18961 cttaaccttc aagactaatg gcgatgcatt ttcttctgta atctcttgaa tatccatcca
    19021 aatatatcca agtgaatcat tcgcaccatc agacacagct tccgaagtcg taacttgagg
    19081 tgcactctca ttcatttcaa catcatacaa ggccatgaca tggtgaacca taaaattggt
    19141 taactcttct ctgacgaaaa catcgtagat tcgaggatta gagtagctta taacagtaaa
    19201 tcccgtctct tccataactt ctctagtcag cgtttccgtc agtccttcac caagttgctg
    19261 actgcctcca ggtagatcat accgatgttg ataagggcct ctcgcttttt caatgcagag
    19321 taacttccca ttttctaagc aaacagcgta gactccaaag tgttttttga tttccatcca
    19381 actcctccta cttcaaagac cagccaccat ctattgtcaa gatttgtcct tgcatggcag
    19441 atgcctttcc actggccaaa aagagactga cttctgccac ttcctctggt tcaatccagc
    19501 gcttgattgg tgtttcacta gccacccagt cagctaagcc acctggctca aaatccgcag
    19561 cggtcatagc cgtcttgact gctcctggag caatcccaaa gacctgaatc ccagcttcag
    19621 catagtctag agccaactgc ttggtgaagc cagccaaggc atgcttggat gaagtatagg
    19681 cgtgaccacc tccacctgct aggctagaag caatggaaca catattgatg atgattccct
    19741 ttttattttc cagcatttgt gtcaaataat accgagtcaa ctcaacagga gtcatgtagt
    19801 taatttcaaa aatctcttga atttcctgcg cagtctgttc caacagtggt ttgtaatcat
    19861 ccaaaactcc agcagtatta cacaaaacat ccacctgagg gcaccagcca aaaataggtt
    19921 ccaagtccaa ggtcaaatct ctctgtaaaa aatggaaatc accctctaag agtggatttt
    19981 caccttggtc aactccataa acttgaaagc ccttctctaa aaagagtcga gcctgagcca
    20041 atccgatacc tgaactcact cctgtaataa gtacacgttt agtcatgcac ttctacccaa
    20101 tccgttgcca aaacatcaca agctgtcggg ctccacatgg aaaaaccttc tccttcgcca
    20161 gaaacgttga ttaggaaata aggtgtcact tcaagtgcaa gcccgttttg ttcaatggtg
    20221 tcaaaaagtt ggacatagtt ttccgcacct ccccaaccag ttcgtacata ttttttctta
    20281 gcctttaagc caggtagaat ttcttcaaat gtcatgtttt tctcctttaa tgtcaataat
    20341 tctccccttc attataacaa aaaaaccgct ttaaaacggc tttttgactg tgatttattt
    20401 acatcttctt ctacttacgg caaattattc cctgcagcaa gataaatttc ataccattct
    20461 tttcttgtta agctaaagtt tgccgctcgg ctaacttctc tcaagtgctt aggatttgtt
    20521 gtacctacga ctgcctgcat ttttgctgga taacgcaata tccaagaaat ggcaatagtt
    20581 gaagaggtta ctccatattt aatagctaaa cgatcaagta cttgatttaa agcttgaaat
    20641 ttctcatttc caacaaagtt ccctttaaaa tacccgaatt gcaagacaga ccatgcttga
    20701 atgaccacat cgtgtaattt gcaatattca aaaatgctgc catctcgcat agctgcttga
    20761 ctatcttcca tattaacatg aaaagctgat tcaaatcctg gagtaaaagc cgcactcaat
    20821 tgtagctgat taacagctaa cggctgcttg acatcttttt taagcaactc catcatcata
    20881 ggattttgat tagaaactcc aaaatctcga accttacctt gtttataaag gagatcaaag
    20941 gcttctgcta cttggtcaga ttccatcaaa gcatctggtc gatgaaggag caagctatct
    21001 agatgatcaa tcttcaatct ttgcaaaata ccgtctactg attttataat atagtcctta
    21061 gaaaaatcaa aataggtaaa ttcttcaatg cgaatgccac atttggactg aatccacatc
    21121 ttttctctta aatctggacg attttttagg acaagaccta acagttcttc acaacgacca
    21181 cgaccataaa tatcagccaa gtcgaaggca ttgattccaa cagaaagtgc tgtttctaca
    21241 agctcttcaa cttcttttac agacttatct tttattctca tcattccgag aacaatttct
    21301 gataattctt tgtcatcttg accaagagtt atgtatctca tcaaattttt ctcctttaat
    21361 ttctaacatt cttcccttca ttataacaaa aaaccgcttt gcaacggctt tttgactata
    21421 cttcactcca ttttatcttc ttaaacccac ggaacaagag aaaaatgcca ataaagagga
    21481 cagctaaagg aataactttt gtaaggaaaa catttgaaat tcccatccac tcataataac
    21541 ggagcagaga acccaccaca agatgggcaa taatcatact gacaaatgga cgaaagaccg
    21601 cttctttcca attccaaata ccgataacta gcgaaatcgt aaagacagac aaactatccc
    21661 agggagccgg aatataaaag gctccttctt gtatgaagct tgccattcct acatatccta
    21721 aaacaactag aagaactata gtcccaacaa caatgtaagt gccaattttc attttaggag
    21781 aatcttggac taaacttctt cgtaaaattg tggccacaag tccaaatcca atcagaaaaa
    21841 taagaagttg ccctaaaaat gtgagcaaat tgactgttaa gagaggacct ttagaaaaat
    21901 cacttagtag ttgataataa cgtaataccg ccaggacaag aattggcgtc aaaagggact
    21961 ctttgataga actgcgaggt gctcccttga gaatctcttt cattattttt ttaggattct
    22021 tacctagata atcctctgca ctcatgccat ctcgttctgc ttctgagaaa tctagcatca
    22081 tcaaatagat ctgctctctg agatagtctt catcatagag aaatccagca agattaaaac
    22141 tttcccacaa ctcctcaaaa tacttttgat tctcctcaga aaactcatgt agcaaagcgc
    22201 ttgtttcttc gtaatacttc attttcttca tggtttaacc cccattctta atcccttcta
    22261 ctttttgact caaatcgtcc cattgctgcc aaaagactga gacacgctct tctccttctt
    22321 tcgttaatga aaaatacttc cgatctggac catctggcga cgggcgcatg tcgcctctta
    22381 tccattgatt tttttctaac ttttgcaaca aaggataaat agttcctgga acgatagtat
    22441 caaatccagc ctctcgcaaa gtctgaacca actcataacc ataccgctct ttttgaccaa
    22501 tcatatccaa gaaacaacct tcaagaacac cttttaatag ctgagtttct ttcatcactt
    22561 ctcccttcta atctattttg taatacctac tagtaacttc acctatagta tattacttct
    22621 acactagttt gtaaagcata atagttaata ctcttcgaaa atctcttcaa accacgtcag
    22681 cgtcgcccta ccgtatgtat ggttactgac ttcgtcagtt tcatctacaa cctcaaaaca
    22741 gtgttttgag ctgacttcgt cagtttcatc tacaacctca aagcagtgct ttgatcaacc
    22801 cgcggctagc ttcctagttt gctctttgat tttcattgag tataaataaa aaacagaact
    22861 agcctgaact agtcctgtct acttttaccc aatcacactt ccatttggta cagctggatc
    22921 aactgtgaga agggttaatt tgccatcatg ttcagctgag agaatcatac cctggctgac
    22981 atattttttc atcattttac gtggtttgag gttagcaacg atttgaactt tcttgccgac
    23041 caattcttgt tcatttggat agtattttgc aattcctgaa agaatctgac gatcttctcc
    23101 atcaccagca tccaagcgga attgaagcaa cttatctgaa ccttctactt tagacacttc
    23161 tttgacttct gcaacacgga tttcaacctt gtcaaagtct tcaaacttga tttcatcctt
    23221 gtttagtttg agctcaactt cgtccggatt ccattctttt tcgactgctg gtttattgcc
    23281 ttccatttgt tccttgatat aggcgatttc ttcttccata tttagacgtg gaaagatagg
    23341 tgttcctttg gcaactacag tcacatctgc tgggaagtca gccaaactca agttttcaag
    23401 actagaaact tcttccaaac caagttgagt caaaactgca cgactagttt ccatcataaa
    23461 tggttcaatc aagtgagcaa ctacacgaat gctggctgcc aagtggctca tgacacttgc
    23521 caattggtca cgaagagctt catccttggc caagacccat ggtgcggtct catcgatgta
    23581 tttattggta cgagagatca gagtccagac tgcttcaagc gcacgtggat agtcaactgc
    23641 ttccatgtgt gtatggaagt ctgcgattga tttttctgca acctcagcaa gaacatgatc
    23701 aaattcagtc acaccttcta cataggcagg gatttgtcca tcaaagtact tattaatcat
    23761 ggaaaccgta cggttaagga ggttcccaag gtcattagcc aattcatagt tgatacgacc
    23821 gacatagtct tcaggagtaa aggttccgtc tgaaccaact ggaaggttac gcatgaggta
    23881 gtaacgaagt ggatctagtc cataacgctc taccaacatt tcagggtaaa cgacattccc
    23941 ttttgactta gacatttttc cgtctttcat gacaaaccaa ccatgggcaa tcaaacgatc
    24001 aggtaattta acatccaaca tcataagaag gattggccag tagatagagt ggaagcgaag
    24061 gatgtctttt cctaccatat ggaagactgt tccattccag aacttgtcaa agttaccatg
    24121 ttcgtcttga gcgtagccaa gagctgtcgc atagttaaga agggcatcaa tccaaacgta
    24181 gacaacgtgt tttggatttg atgggacagg cactccccat gtaaaggttg tacgagatac
    24241 cgccaaatct tccaaacctg gctcgatgaa gttgcgtagc atttcattaa gacgaccatc
    24301 tggcgtgata aattcaggat gatctttgaa aaattcgacc aaacggtctt ggtatttgct
    24361 aaggcgaagg aagtatgatt cttcagaaac ccattcaacc tcatgacctg atggagcaat
    24421 accaccagtc acatttccag cttcatcacg gaaaacttct gccagctggc tttctgtaaa
    24481 gaattcttcg tctgatactg aataccaacc agagtattca cccaagtaga tatcatcttg
    24541 agcaagtaag cgttcaaaga cctgtgcgac aactttttca tggtagtcat cagttgtacg
    24601 gataaattta tcgtatgaga tatctagtaa ttgccagagt tctttaactc caaccgccat
    24661 tctatcaaca tagacttgag gtgtaatacc agcttcttcc gctttctgct ggattttctg
    24721 accatgttca tcaagacctg tcagataaaa tacatcgtag cccatcaggc gtttgtaacg
    24781 tgctaggaca tcacatgcga tagttgtgta ggcagaaccg atatgaagtt tcccagatgg
    24841 atagtaaatc ggcgttgtaa tataaaaatt cttttcagac ataatttttc ctttccaggc
    24901 aaatgaaacc tgtttttcta acacttcatt atatcacatt tttaatgaat ttcgataggg
    24961 aaatccatac aaaaacaaga tagacgagtg tccatcttgt tgatcttatt cataacgaag
    25021 ggcttcaatt ggatcaagtt tcgatgcctt gttggctggc aagactccaa aaatcatacc
    25081 aacactagcc gaaactgcaa gactaaatag ggcaactggg attgatactc caacttctat
    25141 accttctatt aaaccttgca gtaacaaacc tgctaaggca gttaaaccac ttgcaattgt
    25201 caagccaatt aagccaccta acaaggtcaa aatcatggat tcaatcaaaa actgaattaa
    25261 aatattggca cgtgttgcac ccaaagcctt acgaagacca atctcacgag tgcgctctgt
    25321 caccgaaacc agcatgatgt tcatgacacc agttcctcca acaaagagag aaatccctgc
    25381 gatggaacta ataatcgtcg tcataaaact aaacgattgt tgaatttctg caaatacaac
    25441 ggactcatct gccacctggt attctccctg ttgtaagcct gcaagctctg tcatttttcg
    25501 tgccagttct ggacccagag ttggggttaa actggtatca ttcactcgaa agacaatatt
    25561 agctatttca tctacattaa aattcgcagc aagggagata ttggtagtaa taggcaagcc
    25621 accaaaccca tatatttttg atcttttagc ctccggacta gtataaaccc caatgacccg
    25681 gtaactaaat ccattgactt ctacaacctt gttaatagcc tcttgaggag attcaaataa
    25741 actaatggac aattcctcat ctagcaaaat gacacttgca aactctttga aatcttgctc
    25801 tctcagacta cgacctgcaa taatttcatt cttaacagcg tccatgtaag ttctgtttcc
    25861 acctgtcaaa ttagcattct caaccttttt atcttgatag gtcaagatgg cattcgttga
    25921 attggttaca tagtaactat ccactccctt cagtttagct gcctcttgaa cccaggattc
    25981 ttgcggtttt ggcggttcaa caggaacttc ctcttccttt ccagaaaccg taaaagctga
    26041 ttgtttctga gtaaaagacc catctttact ttttttagga gagaaaaaga cgctaatatt
    26101 tttctgaaat ttagtcatat ctttattgac ttgacgagat agggaatcac ccaaagccat
    26161 aatcacaaca actgatgaaa caccgataat aatcccaatc atagtaagca aagaacgcat
    26221 cttgtgagcc atgatagatg aaaaggcaaa tttcagattc tgcatcttag ttttcctcct
    26281 ttcctaactg agcactgtca gacgaaatga ccccatcccg aatgacaatc tgacgtttgg
    26341 cataggcagc aatctcaggc tcatgcgtta ccatgataat ggtttttcct tctttattca
    26401 aatcaaccaa taattgcata atttggttac ctgttttggt atccaaggct cctgtcggtt
    26461 catccgctag gataatagaa ggattgttta ccaaggcacg cgcaatggct acacgttgct
    26521 tttgaccacc agataattct gaaggtaaat ggtgactacg ttctgtcaat tcaaccttgt
    26581 ctaaatattc ctcagccaac ttgcgacgtt ttgaagacga aactcctgcg taaatcaagg
    26641 gcaattctac attttgcaga gcattgagct tcgatagaag aaagaactgc tgaaagacaa
    26701 aaccgatttg ttggttacgg accttagcca gttgtttttc accaagccca gccacttctt
    26761 gaccttcaag ataatattct ccactggttg gtgtatccaa catgccaatc gtattcatca
    26821 gagtggactt accagaccca gatggtccca tgatggctac aaattcaccc tcattcactt
    26881 ctagattgat atttttgaga acctgcagtt cttggtcacc attacggtag cttctgaaga
    26941 tattttttag actaattagt tgcttcatca gccttcacct cttttccttc ttccaaggaa
    27001 gatgttggat tactgatgac cttagcacca tttgtcaaac cagaagtgat ttcttgattt
    27061 tctgcgtcag catttcccaa tgaaacctca acttttttag ccttttgttg ttcatccaca
    27121 atccagacat aatttttact atcatccatt actagactgc taacaggaac aagaatagcc
    27181 ttagttttgc ttttaacctc aatgttgaca gaaaaacctt gtttcaaatc accaacctcg
    27241 cctgtcacat caatagtata agggtattta gaacctgtat tattcccggc tgctggacta
    27301 gctgcttcac cattgttttt aggatagtca gaaatatagc ttaatttccc agtccatttt
    27361 ttatcaggat acactttaga agtaaagctt acttcttgac ctacagaaag gttggctaga
    27421 ttgtactcag acaattctcc cttgacttgt aaattttcat tgctgacaat atgaaccata
    27481 acttgactcg cccctgttgg agatttagaa acattgctat tgacttcgac cacagttccc
    27541 tctagggtac tgagaacagt tgttgcatcc aattgacttt gagccttgct taattgcgcc
    27601 gcagcatctg cacgcgcatc acgggcatca cccaattgag cgtcaataga agcaacagaa
    27661 tttccagcca ctggagttgg gctttgcacc gttgcatctt ctcctcctac tggcgctggt
    27721 aactgtggag ccggagctga agcggcttca tttcgtgctt gattgagttc attgatatga
    27781 cgatctgccc tagctactgc tcgactagct gaatcatagg ccgcctgcgc ttctgaacta
    27841 ctgtacttga ctaaagcctg cccttcgctg accttatcgc ccacagaaac aaggatttca
    27901 tctaaatcac ccttactagc atcaaaataa acatattgtt cattttttgc tgttactgtc
    27961 cctgacaata aaacagagga ggccacgctt ccttccttgg caacaacaag atgagtaggc
    28021 tcatctttta gagcagtctg agaaggttgt ctaaagagta aaatcccccc agcacccaat
    28081 acaactacac tcgcagcacc gattgctgca tacagttgcc actttttagc tttaccattc
    28141 tttttcttca taatgaaact ccttttcttt tttacaatac tttgctatta taccaaattt
    28201 ccctccagca aacaatacag ttcaggatta aacaatcgtt cggaattttg cttttctatt
    28261 gtactagata tataatacac tatcttgact tatttggcaa gcttttttgc aattttttgt
    28321 gcgtagcaga tttttgcaat caaatcaaaa aaagaataaa atataactat caaaaaagac
    28381 gctctactat ttaaaagatt acaaaggagt tttcaatgag agaatatgat atcattgcta
    28441 tcggtggagg tagcggagga atcgctacca tgaaccgtgc tggtgaacat ggagccaaag
    28501 cagccgttat tgaggaaaag aaattaggtg gaacctgtgt caacgtcggt tgtgttccta
    28561 aaaaaatcat gtggtacggg gcgcaaatcg ctgagacttt ccatcaattt ggagaagact
    28621 acggctttaa gactactgat cttaactttg actttgcaac cctacgtcgc aatcgtgaag
    28681 cctacattga tcgcgctcgt tcttcttatg atggtagttt taaacgcaac ggtgtagact
    28741 tgattgaagg tcatgctgaa tttgtagatt ctcatactgt aagcgtaaat ggtgaactga
    28801 ttcgtgctaa acatatcgtg attgctacag gtgcccatcc aagtattcct aatattcctg
    28861 gtgctgagct aggtggctct tctgatgatg tatttgcctg ggaagaactt ccagagtcaa
    28921 ttgccattct aggcgctggt tatatcgccg ttgaattagc tggcgtactc cacacttttg
    28981 gtgtcaagac agatctcttt gttcgccgcg atcgtccttt acgtggtttt gattcctaca
    29041 tcgttgaagg tttggtcaag gaaatggaaa gaacaaactt accacttcac actcacaaag
    29101 tccctgtcaa gttagaaaaa actactgacg gcattaccat tcatttcgaa gatggtacta
    29161 gtcacacagc tagccaagtt atctgggcta caggtcgccg tccaaacgtt aagggcttgc
    29221 aacttgaaaa agctggagtg actctgaacg aacgtggctt tatccaagtg gatgaatacc
    29281 aaaatactgt tgttgaggga atctatgctc taggtgatgt aacgggcgag aaagaactga
    29341 ctccagttgc aatcaaggcc ggacgtaccc tatctgaacg tctctttaac ggaaaaacta
    29401 ctgcaaaaat ggattactca actattccaa ctgttgtctt ttcacaccct gctatcggaa
    29461 ctgttggttt gacagaagag caagctatta aagaatacgg tcaagaccaa atcaaggttt
    29521 ataaatcaag ctttgcatct atgtactctg cttgcactcg caaccgtcaa gaatcccgtt
    29581 tcaaactcat aacagctggt tcagaagaaa aagttgtcgg acttcatgga attggctacg
    29641 gcgttgatga aatgattcaa ggatttgctg ttgctatcaa aatgggagca accaaggctg
    29701 actttgacgc aactgtagcg attcacccaa cttcatctga agaatttgta accatgcgtt
    29761 aatcgaaaca aaagaagcta atataaatat gtctgcttct tttttaatga ttttcgaatc
    29821 aacaaaaaaa ttatccaact tgactagtca cgaaaatcgg ctgttacagt ttttgttacc
    29881 ttgtttttaa aaaatggttg acatcgactc ctatatgagt ataatagtta gtatacatta
    29941 gaaaagaggt taactatttt gaaaaaagct cacgtttatg ctatccctgc tattggggct
    30001 gctctcattg ctgctttggc acaaatcagt cttccaattg gacctgttcc cttcactctg
    30061 caaaactttg caatcggctt gattgctact gtctttagac cgagagaggc tgtactttct
    30121 gctggactct atcttcttct aggtgctatc ggtcttcctg tctttgcagg aggtggagct
    30181 ggttttcagg ctttagttgg ccctactgca ggctatcttt ggttttatct cgtttactct
    30241 ggacttactt cctctctaac caacagcaag agtggtgttg ttaagatttt tcttgcaaac
    30301 ctcttgggtg atgcccttgt ctttgtcggc gggattctca gcttgcattt cctagctgga
    30361 atggcatttg aaaaagctct tgttgtgggg gttcttccct ttatcattcc agaccttggc
    30421 aaacttctgg ctattagttt tattagccgt cccctacttc aacgccttaa aaatcaggct
    30481 tactttacta actaaaaaag gataccgagt tatcatgact caatatcctt tttttatttt
    30541 gaaaacttat actcaatgaa aatcaaagag caaactagga agctagccgc aggctgctca
    30601 aaacactgtt ttgaggttgt ggatgaaact gacgaagtca gtaaccatac atacggcaag
    30661 gcaaagctga tgcggtttga agagattttc gaagagtatt agttgccttt aaaggcatcc
    30721 accatcgttt gaaattcttc atttgagaga gtaatccctt tgcccatttt agtatggtct
    30781 ggactccaag cacgaatatc aaactttgca ggggcaccat taaagctcac acggttaatt
    30841 tccttggtcc aacctttttc gttttcagaa agagtcaaca agtgctcttc gatttcaaat
    30901 gtaaattctg ccattttctt ctcctttttt agtttcatta gtttattcgt aaaatcttgt
    30961 agattttagg aaaattttat ataatattga tataaaagaa gggaggccaa tatgagacat
    31021 aaattccagc aagttctaaa taaaatacat gattttttaa atggatatga ccaacctgac
    31081 cagactgaaa ccaactccct tacagccact attgaagagg ctatccagaa acaaaccgct
    31141 gttcacctta tcttatctga gacaagcttt acaggtgaca tcatcaaata tgatcagcaa
    31201 ggccagcaaa ttatcgtgaa aaatttttcc aaaaatgtga gccggattat ccgtataagc
    31261 gatattcaac gcctgcgatt tgtcccctca actgtccaaa cagcccaaaa aaataaattt
    31321 aagaaagagt gagatgtagt tgcttcatcc cactcttttt cttagcgaat ttgttcaaaa
    31381 tgtaaatgaa ctgcgatatg atctccataa ccacttcttt ccaagtcacg ttgtaaacga
    31441 taggaaatat agtgttctgc aatggtaatg taacctgcgc ccaataaacg atgttcaacc
    31501 atagattgaa tcatactgat agtcgcacgt tccaccttgg cttcttgtaa atccaaaact
    31561 accttcttag tgacttgagc aagattttga cgcaaatcat ctgtcaaaac ataaacagtt
    31621 tgggctgcct tcaagatggc ttggtaaatc ttatctggat taaattcagc aatttcgcca
    31681 ttacgtttga ttacttgcat aggtttctcc tttattcttt gttttctttg atttctgcca
    31741 gcattttttc ttcttctact gtcagttgat aatgttcaag taaatccggt ctgcgctcgt
    31801 aggttttctt taaactctcg tacaatcgcc actgacgaat cttttcatga tggccactca
    31861 tcaatacatc tggcacgacc atgcctcgat aatcataggg acgtgtgtac tgaggatatt
    31921 ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga ctccttgcca atcacttctg
    31981 gaatcaggcg aactgtagca tcaatcatgg tcatagctgc caattctcca ccagtgagga
    32041 catagtcacc tagggaaatc tcatctgtta ccaaggtctt aatgcgctca tcataaccct
    32101 catagtgccc acagataaag attagctctt cctcttgagc caaatcttca gcataagcct
    32161 gatcaaactg ctttccagca ggatcaagga gaataacgcg cggatttttc ttttcaatag
    32221 catcaaagga atcgaaaata ggttgtgctc tgagcaacat gccctgaccg cctccgtagg
    32281 gctcatcatc tacatgacgg gccttttcag cattttctcg aaaattatga tactggatat
    32341 ccaagagccc tttttctcga gcctttccaa cgattgagtg ctccagtgga gaaaacatct
    32401 ctggaaagag ggttaaaata tcaatcttca tcgtctaacc cttctaagat ttccacatcg
    32461 acccgtttac ttggaatatc aacattgaga accactggtg ggatataagg taaaagcaaa
    32521 tcacgtttgc cttttcgttt gaccacccag acatcattag cacctggttg caggatttcc
    32581 ttgatggttc caaccaagct atcaccctca tagacttcca aaccgataat ctcgtgatag
    32641 taaaattcac catcgtctag gtcattcaaa tcttcctcag cgaccttgag actgtatccc
    32701 ttgtactttt cgatagtatt gatatggtac atatctttga atttaataat gtcaaagttc
    32761 ttctgtttac ggtggctagc gatggtcact gtttggacaa actgatcttt ttcatcaaac
    32821 aaagccagct cagctccttt tttaaaccgt tcttctgcaa aatccgtcac agacaagact
    32881 cgcatctccc cctgtaatcc ctgcgtatta acgattttcc caacattaaa gtagttcatc
    32941 ttgtctcctg taatctcctt ttttccatct tattctgaca attctcgaat aatagccgca
    33001 attttttccg attctgacca ttgtaaataa tggtgattcc ctcctaaaat gagtttagta
    33061 ttggaagtcc aatattctga ttctctgtac tctttttctc tataagtctg acaaaaaata
    33121 aatacaggaa catgagattc tatcgacaaa ttctcaaaat cttcctcagt aatctctcca
    33181 gatatctgaa attctggatc ttgattttcc aactctaagc ctttttcttg cattaattcc
    33241 cagatttttt tattcgtttc aggactaaat gttgcttgag ttaagttctt aaaataaagt
    33301 tcaggaccac actcgtcaat cagtctcatc tgctcttcca tttctggata aggattttct
    33361 gaaaaatcag caaacatgac ttttttagtt gtcggttcaa ttgctactaa agtctgacgc
    33421 ttaattggtt tctcgagtaa tttgcaagct aaaattccac tccaactatg tgcacaaagt
    33481 atatattcag aaattcctaa ttcttcaagt acttcataaa ccgcatctgc aagattatct
    33541 agtttttttc cagcttggtc atgaatcgga ctcctacctg tgttcggaaa atcaattgtc
    33601 aaataaccaa ttgtaggagg aggtttttca agtataagtg aaaaattttc ataacttggt
    33661 agcaaacctg ctccgtttag acaaactagc actttctttt gcttttgata agtaacagag
    33721 aggctaccaa tttctgtaga tacttcaaac ctcttcataa agaaatccac tgattctata
    33781 taatgaatta ttaaaaatcc ttatccttta ttttatcacg ttccaaggat tttctcaagt
    33841 tggaggaagg ggacaacatc tctactttcc cttcaagaat ccttccaaat tatgtttatg
    33901 ttggtaatta acggctgcgg ttttgtcttt ctcaaagaca gtcttggtaa ggtcaatatg
    33961 attaatagct acgattgcga cggtgtagta aatgatatca gccagttctc tggcaagttc
    34021 ctcgttcgaa tcctatccct tcttttcgac cagagcgcct attcaaaacc tcggctactt
    34081 ctccgacttc ctccactaac ttcataaaga gaccttcatc agtccgagac tgctgttaat
    34141 gttcgattaa gtagtcttgg aattgcctaa acgttcaatc ttttatagta tattgaaact
    34201 agaatagtac acctttactt ctaaaacatt gttagaaatc gatttgactg tcctgatcga
    34261 tttgtcctgt tcttgtttca ttttactata tcttctattc cacacaaaaa agcgagacat
    34321 ccgtcccgcc cttcttattt ttcgtcaata acgattctta cttttttgta ttcagttggg
    34381 acagagtaga caatcgttct tatcgcagaa atagtgcgac ccttacgacc gattacacga
    34441 cccacatcgc tttgatcaag attcaaatga tattccaaaa attctggtgt atcctcaatc
    34501 ttgatagtta aggcatctgg ttgtgaaatt aagggtttca caatcgcaat aatgagattt
    34561 tcaatcgtat ccatctgtca acctacttta aacttatttt gagaatttag aatcgtggaa
    34621 ttttttcaat acgccttctt ttgaaaggat gttacgtact gtgtctgaag gttgagctcc
    34681 attagccaac catgcaagaa cgcggtcttc tttcaaagtt acttggtttt cagcaacaag
    34741 tgggttgtaa gttccaactg tttcgatgaa acgtccgtca cgtggtgaac gtgaatctgc
    34801 tacgttgata cggtagaaag gttttttctt agaacccata cgagtcaaac ggattttaac
    34861 tgccattttt aaagtctcat ttctttaatt ttttatttcg gtgaaatagc tgagctattt
    34921 agcacatgtt ctattatagc agatttctgg caggtgtcaa gaaaaaaact tgacagacta
    34981 taaatttctt aaagcattta gaaatttgtt agaataggaa ataaatgttt gaaagatgct
    35041 atccgtgaat actattttag aaaaatttta taaagaacac caagtcaaac ccttcatatc
    35101 gcctgaacgt gatttggata cttggcttct aagtcccaaa cccgttccca agcgaaatat
    35161 ggacttatta gcagatgatt cactagcagg agatatcatt ttactatgga gaatccagtt
    35221 tggtactttt accactgaaa cataatttta aaaactccca ttcgaatatg attcaaaatt
    35281 cgcttagaat caatgttttc ccactttttc aaaaaataaa ttttcatcta atttaaataa
    35341 ctttcaatta agtgtgaatt ttgcttaaaa tcataaaaaa acaccccatg gtgtgaacca
    35401 tgaagtgttg taaatgctgt attgtagcta gttcttaacg tttagagaac tggctagctt
    35461 tacgagcttt cttaagatct ggttccctaa atactttgag tacacttatg gcattgatgc
    35521 ccctaaacat ctaaaaactc tggtagaaaa agggtatgct cttgtcgaaa cttcttttga
    35581 ctcacttgac catctaaata ctaccatgaa aaagaatatc ctgaagaaga agggagttac
    35641 tggactttct aaaatgaaat cttgcgacct ggatcaagct cttcatgagc atttttcaga
    35701 agaagaatta gctggtcact ttcatgtcct tctatggact tttttacaat ggcattgcta
    35761 tcacacccaa tacctatcta agcgcctggt tcgtaaactt tattgcagct cttcctctaa
    35821 atttcctaat tgttgaacca attgcccgtt ttatactaag ttcttttcag aaaccattta
    35881 ctggggaaga agttgaagat tttcaagatg atgatgaaat cccaactatt atctaagcca
    35941 gttctgtaaa ctactaatat ttgaaatcca cttcctttta gggtacaatg gttataaatg
    36001 aatttttgag aggatcagaa tgaaaaaact agcaaccctt cttttactgt ctactgtagc
    36061 cctagctggg tgtagcagcg tccaacgcag tctgcgtggt gatgattatg ttgattccag
    36121 tcttgctgct gaagaaagtt ccaaagtagc tgcccaatct gccaaggagt taaacgatgc
    36181 attaacaaac gaaaacgcca atttcccaca actatctaag gaagttgctg aagatgaagc
    36241 cgaagtgatt ctccacacaa gccaaggtga tattcgcatt aaactcttcc ctaaactcgc
    36301 tcctctagcg gttgaaaatt tcctcactca tgccaaagaa ggctactata acggtattac
    36361 cttccaccgt gtcatcgatg gctttatggt ccaaactgga gatccaaaag gggacggtac
    36421 aggtggtcag tccatctggc atgacaagga taagactaaa gacaaaggaa ctggtttcaa
    36481 gaacgagatt actccttatt tgtataacat ccgtggtgct cttgctatgg ctaatactgg
    36541 tcaaccaaac accaatggca gccagttctt catcaaccaa aactctacag atacctcttc
    36601 taaactccct acaagcaagt atccacagaa aattatcgaa gcctacaaag aaggtggaaa
    36661 ccctagtcta gatggcaaac acccagtctt tggtcaagtg attgacggta tggatgttgt
    36721 ggataagatt gctaaggccg aaaaagatga aaaagacaag ccaactactg ctatcacaat
    36781 cgacagcatc gaagtggtga aagactacga ttttaaatct taaaaaccaa aaaaatacag
    36841 tatccacatt cggtactgta tttcttttac tctcattctt aagttaaatt attaaaatcc
    36901 catatttggt ctatccagcc ttcataaaag tctggctcgt ggcagaccat aaggatagat
    36961 cccctgtatt ctttgagagc gcgtttgagc tcatcctttg catccacatc caaatggttg
    37021 gtcggctcgt ccagcactaa aacgttgttt tcacgattca tcaagagaca gaaacgaacc
    37081 ttggcttgct ctccccctga taatacttga atctggcttt caatatgttt ggttgtcaaa
    37141 ccacaacggg caagggctgc acggacttct gcttgattaa gggcaggaaa ggcattccag
    37201 acagcttcaa gaggagtttg gcgattaccg ccttctactt cctgctcaaa ataaccaagt
    37261 tctaaataat ctccacgctc cacttcccca gcgattggcg agataatgcc caagagactc
    37321 ttcaagagag ttgtttttcc aataccatta gcaccaataa tcgcaacctt ttgattgcgt
    37381 tcgaaggtaa gatttaaagg cttagtaaga ggacggtcgt aaccaatttg caagttcttg
    37441 gcttggaaga taaagcgccc tggtgtacga gctggtttga aatcaaagga tggttttggt
    37501 ttctcacttt ggagttcgat aatatccatc ttatccaatt tcttttgacg agacatagcc
    37561 atattacgag ttgcaacacg ggctttatta cgagccacaa agtccttgag gtctgcaatc
    37621 tctttctgct ggcgttcgta ggctgcctct agctgagatt tcttcatagc ataaacttct
    37681 tggaactggt agtagtcacc agagtaacgc gtcagctgtt gattttccac atgatagaca
    37741 atattaataa cgtcattgag gaatggaata tcgtgcgaaa taagaacaaa ggcattctca
    37801 tagttttgga gatagcgctt gagccaatca atatgctcag catccaagta gttggtcggc
    37861 tcgtccaaca gcaaaatatc aggcttttca aggagaagtt ttgccaaaag caccttggtt
    37921 ctttgcccac ctgacaaaga agttacatcc gtatccatgc caaagtccat aataccaaga
    37981 gcacgcgcta cttcgtcaat cttagcatcc aaggtataga aatcacgact ctccagacgg
    38041 tcttgaagtt ctcctacttc ttccatgaga gcatcaacat ccgcgccgtc ttcagccatt
    38101 ttcatataga ggtcattgat acgagcttca gctttgaaaa gctcatcaaa agccgtacgg
    38161 agaacatcac gcaccgactg tctttcagca aggacagagt gctgatccaa gtaaccagcc
    38221 gtcacatatt tggaccactc aacctttcct tcatctggca gcattttacc agtcacgata
    38281 ctcataaagg ttgattttcc ttcaccattg gcaccgacca ggccgatatg ttctcccttg
    38341 aggagacgga aggacacatc ttcaaaaatt gcacggtcac caaaaccgtg actcagattt
    38401 ttaacttcta aaatactcat tttaattcct tatcttgttt ttatgtaatc gtttataaag
    38461 gagccaagcc agatagccac ccaaagtgtt ggtccacaaa tcatcaatct caaagacgcg
    38521 attgaaatca aagaaaaaat ccaagattaa ttgcgtacac tcgattccaa gactcacaag
    38581 aaaactaaaa agaaggacct tttttgtttt ccgtaaattt ggaaatagat aaaggagttg
    38641 gaaaatcaga ggaaaaaaca agaagacatt gaggatattt tgtaaaaaaa tccaacataa
    38701 ttgtccaatg tcactcactt cgcccagttt ccagagagaa ttgaaaggag tcaaaagaaa
    38761 aaccaggcgt ccaagatgct gaatacctgg agttcccact cccacggtag attgttcttg
    38821 aggagtaaag caaaaacaga caatgcaaat gctatagaaa atgactcccc agaccaaaat
    38881 atgattataa gtcttcttca tcattaagga tttaccgctg cgactgcctt ctggcggtca
    38941 cgtttcattg tgttagagcg caattgtcca caagctgcgt caatatctgt accatgctct
    39001 tgacgaacca cacagttgac cccttttttc ttaagcgtat catagaaagc caacacgcgc
    39061 tctttgggac tacggctata ttggtcatgc tcactaactg ggttataagg aatcaagttt
    39121 acataagaca atttcttgat gttcttgagc aattcagcca attccaaggc ttgttctaca
    39181 ccgtcgttga cttcattaag catgatatat tcaaaggtta cacgacggtt tgttgtctca
    39241 atgtagtatt caatagcagc aaagagtttt tcaatcggaa aggcacggtt aattttcatg
    39301 atacttgaac gaagttcatt gttgggtgcg tgaagagaca cggcaagatt gacctgaacc
    39361 ccttcatcag caaagtcacg aattttatga gccaaacctg aggttgaaac catgatgtga
    39421 cgagcaccga tagccattcc tttatcatca ttgatagtac gaaagaaatt caagacattg
    39481 ttgtaattat caaagggctc accgattccc atgacaacga tatggctgac gcgttcatcc
    39541 tgaccacgct catcaaagta tttctgaacc agcatgattt gcgctacgat ttcaccgtta
    39601 ttgaggtcac gttgcttctt aatcaaacca gaggcacaga aggtacaacc gatattacag
    39661 ccgacctgag tggtcacaca gacagataaa ccatagtgtt gacgcatgag tacagtctca
    39721 attaacatac cgtcgggcaa ttcaaagaga tatttgactg taccatcagc agactcttgc
    39781 acaatacgtt gtttcaaggg attgaccaca aactggtcat tgagcttagc aatcaaatcc
    39841 ttggaaaggt tggtcatttc ttcaaatgac tgcacacgtt tacggtagag ccattcccag
    39901 atttgatctg cacggaattt cttttctccc tgctccaata cccattcctg catggtttga
    39961 tgtgccaaac tatgaattga gggtttcatt tcttctcctt attctctact cacttctgac
    40021 gaatgacaaa atgacgttgt cccttgtcct ctttctgaga atgctggtct ttctgacgac
    40081 gtctattctt cttatctgca ttcgactttc gtttagtttg agtcggtttc tttccttttc
    40141 tagaaggtgt ttcttcttcc gtcttacgca ttttcttgtc aaatgatgct cgcttagggg
    40201 cttcattttc taagacaaaa taggcacaac cataactaca atactctaaa aggtagtctt
    40261 gtaaacgact gattttttca agtttttctt ctgttcggtc atccttgtaa aaacctcgta
    40321 ggcgaagctg ttcgttgctc cagtccccca cgatataatc aaacttggtt aatacttctg
    40381 aaaaacgctg attaaaagtc gtcacatcaa aggcatcctt gatattttca accaaggaaa
    40441 aagctatccc ttccgtttcg accttgtccc cgtgtaaatg gaactccgga ccaggaaact
    40501 tgttatagtt gtataattca ggtgcaattt cttttcgcat agatatcctt ttttcacgat
    40561 tacttaatac tttattctac cataatttct agcagttagc acgtttctca taaaaatgaa
    40621 aaaagtctaa cgattttgtc agaccagaat cttataacct aaaaaagaga agaacaattc
    40681 ttccctccaa ctatcattat ttagcagctg cgtacaattc atctacttta ttccagttga
    40741 ttactgaaaa gaaagctttg atgtagtcag gacgcacgtt gcggtatttc acgtagtaag
    40801 catgttccca aacgtccaag cccaagattg gttttttacc ttctgagatt ggtgtgtctt
    40861 ggtttgctgt tgaagtcact tcaagttttc cttctttgtt gacaaccaac catgcccaac
    40921 ctgaaccaaa acgagttgtt gctgctgcag tgaaggctgc ttggaattct tcaaatgaac
    40981 caaatgttgc atcgattgct gctgccagtt ctgctgaagg agctgttttc tcgggagtca
    41041 tcaattccca gaaaagagcg tggttcaagt gtccgccacc attgttgata agtgcttgac
    41101 ggatatcagc tgggatagat tctacatcag caagcaaggc ttcaaggtct tcaccgattt
    41161 cagggtgttt ttctaaagct gcattggcat tgttgacata agtttgatgg tgtttgtcat
    41221 ggtgcaaatg cattgtttcc gcatcgatgt atggttccaa agcgtcgtat gcatatggaa
    41281 gttctggtaa gataatagcc atctgtaata cctctttttc tttctatatg aaaatgataa
    41341 cgcaaacatt cacttttttc aagttttttg cttatagata aggaaatcac tgacatactt
    41401 tctaataaaa taagcaaatc agcaagaaac ccacgacaag ataatcctga tgcgggttgt
    41461 agtttcaaca aatgtcaatt gacctgacta gcaatctgta agagtgcctt ttcaaaaagg
    41521 aaaccttttt cataaagacc tgtcttaatc tgatagtctg tctcaatcaa ataggaaata
    41581 gcttgcttca gaaagctcaa agaaagtcct ctcgaatctc ttaatgcaaa cttgatttga
    41641 taaggatttg ggttacgtcc cagataacta cctaaactac ttgcaatctg cgattctgtt
    41701 tggccagact ccgccaaaat cttcacctga gtaaaagtcc gaaattgtcc cagcatgact
    41761 gcaatcagtt tgatttcatc ttccccttgc aaggtcaagt ctctcaccaa atcgcgcgcc
    41821 tgatccatct ttttagtcag aataaactga gttaaatcaa aaatattgtc ctgcaaggtc
    41881 ttgggaattg cgttaacaat atcctcttcc tcgataacag aatccgcctt ataggactgt
    41941 aaaaagagaa gatttttctg gatttcgcta aattgaaacc ccgacttgat gaggagattt
    42001 tcaaaagaat gattggtaaa ctgcagacct tgtttctgac tccacttttg gaagtactgg
    42061 cgcaattctt gttcttttac ttctactgca tcgaaggcct tggcatcacg cttaagtaat
    42121 ttgactaacc gtcttttgct atccagcttt ccttctgcaa agattatcaa cttggttgtt
    42181 ggagaaggat tgtcaaggta ttcctcaaat gacttaagct catcatctgt caaaaagcgt
    42241 ttcttagcag tcgtgatatc cataaaataa tctaatatca cgattttctc atccgcaaag
    42301 aaaggaaggc tgaccaactc cagttccaca tccttgtaaa ctacttcttt catatcaaag
    42361 taggcaaagt tgaggtcagc agaatcatac ccaatctgtt tcaacacttg actcttcatc
    42421 acttcaaact gaccctgatc tgtccctgta aataggctca ggctcggtaa atttgataaa
    42481 gtcaacttct gactttcttc aatggctagc atcgtctctc ctttcttcag atttttcgat
    42541 ttaatttagt caatatagcg caatttccca cggaaatctt ctaagctctc gtagcctttt
    42601 tccaccatga ttgctttcag ttcattggta atgcggtcaa aagcactgac gccttctttg
    42661 tgaagggtcg ttcccacctg caccatactt gctccacaga ggatgtgttc aaaggcatct
    42721 cgaccagtca gaacgccacc tgttccgata atttggattt gaggatttaa acgttgataa
    42781 aaggcgtgaa cattggctag agcagtcggt ttgatgtatt ctccaccaat tccaccaaaa
    42841 ccattcttag gccgaataac gacagattcg tcttctatat agaggccgtt tccgatagag
    42901 ttaacgcagt tgacaaactt gagcggatat ttgttgaaaa tagctgccgc ttgatcaaag
    42961 tgaacaatat caaaataagg tggcaattta attccaagag gtttggtgaa gtaagcaaac
    43021 acttctgcca aaatccggtc tgttgtctca aaatcatagg caatctgagg tttacctgga
    43081 acatttggac aggaaagatt tagctcagtc agaccacgaa aatcactctc ttggactttt
    43141 ttcaaaatag tatgggtttc ctctggagac atgccgacca gagataagaa gaaagttcgg
    43201 ttcgactctt tttcctgcaa atctaaaaga taatccaaat aatagtctaa gccattattt
    43261 ggcaagccca tagagttgat ggaaccaagt ggaacatctt ggtagcgtgg ctcaggattc
    43321 ccctgacgga agtccaaggt cgctgtctta gtaacaaagg ttcctgccgc tgagtttttg
    43381 acctcttcta actcctctat cgtcatacaa gccacacctg ctgcattcat caagcaattg
    43441 tcaaactcaa aaccagcaat ttgtgttttc gttgatacca tgattctaat cctccagatt
    43501 tcttttattg ctaatattat accataattt taattctagg tttactagat tctgtggttc
    43561 tatctattta ttcggaaaag aaagtctagt acagaagtca tgctatggaa acagctagtg
    43621 tattagaagt ttgaacaagg cttgggtaac agacttttga atgaagtcca agcaacaagg
    43681 agaaatctca accatgagtc cattccatga ctctgttgct ctagaaaacc ttacaatagt
    43741 caagtgataa cgaataaaac tttggattga aatatcccca agattatcta ttacgaggag
    43801 aaatcttaac ctttatcatt tttaaagaaa tatagtaaaa tgaaacaaga acaggagaaa
    43861 tcgatcagga cagtcaaatt gattgctaac aatgttttag aagttgaggt gtactattct
    43921 agtttcaatc tactatacat gtaaatctct actttcgcaa aatggatttt cagaacagta
    43981 tcccagtata gttaaaaact ataaaaaaga gaggacgttc ccctcttaaa atcttatttt
    44041 actgcttctt tcaaagcatc taccttatcc aaacgttccc atggaagatc aatatctgta
    44101 cgtcccatgt gaccgtaagc cgatgtttga cggtaaattg gacgcttgag gtccagcatt
    44161 tggataatcc ctgcagggcg aaggtcaaag atttgacgag ccgctttttc aagttgactt
    44221 tcagctactg ttcctgtacc gaaagtatcg atacgaacag aaacaggttg cgcaacaccg
    44281 atagcatagg ccaactgcac ttctgccttc ttagcaaggt ctgctgcaac gatattcttg
    44341 gcaatatagc gagccgcata agaggctgaa cgatccacct tagtcgcatc tttaccagag
    44401 aaggcaccac caccatgacg agagtagcca ccataagtat ctacaataat cttacgacca
    44461 gtcaaacctg agtccccttg aggaccaccg attacaaaac gacctgtcgg attgataaag
    44521 aattttgtct tatcatcaag ataagaagat ggaataactt ctttgatgac cttgtcaatc
    44581 acatcttgat ggatttgttc attagtggcc tctggatcat gctgagtaga aataacgact
    44641 gtatctacac gtaccggacg gtcattttca tcgtactcaa ctgtaacttg tgattttgca
    44701 tctggacgga gatagctaat ttctccagac ttacgaagtt ctgccagacg acgaaccaat
    44761 ttatgactga gtgcaattgg caatggcatg agctcttctg tttcatctac tgcaaatcca
    44821 aacatgagcc cttggtcacc tgctccaatc aagtccagtg gatcttgatc agcatttcca
    44881 cgaacctcca aggcttcgtt aacaccttga gcgatgtcag gagattgttc caccaaagat
    44941 gggtgtactc ccaccgtctc agcagaaaat ccatattctg tattggcata accaatctct
    45001 gcaatggtat cacgaaccac acggttaata tccacatagg catttgtaga aatttcacca
    45061 aaaacgtgga cagaaccagt atatacagct gtttcagcag caacgtgcgc ctctggatcc
    45121 tttgctaaaa tagcatccaa aatcgcatct gaaatttggt ctgcaatctt atccggatgc
    45181 ccctcagata cagattcaga cgtgaataat ttacgttctg acataaaaat gtcccccctt
    45241 aaaaaatatt gttatagagt tacaaagtac tgataggaat ttccattatc taagagttac
    45301 tagcttcaga aataaaaacg atactttttt atttctgaag ctagtaaggc gcatagggtg
    45361 accgcagtat ggcagcaacc gtagaaagac gagcgacctc gaagccgtca ttctttgcga
    45421 attgcaaact actgatagga aaactcttcg taataaatac ctaccatctt atcgggacta
    45481 tataacttta tcattatacc atttttaatc gcaatttgca gtctttaatg tagtgtttcg
    45541 gtttagatag ttcgttctca taaagcaaaa agttggagct cagtactcca acaatttcta
    45601 ttaaaatgtt tggcgtttag ctttacgctc tgcacgaccg cgagcgcgat tttcagcacg
    45661 cttggtttta cggcgctttt catcaaccgc ccattgaatt ttcttcttat aacccggttt
    45721 gacttttttc tttttctttt taaccaaacc aatcatttcg atatcaagtt tatcttgttt
    45781 tttctcacgg ttggcacgac gatcacggtc ataggtatct tgaaattccc catctttgac
    45841 catcttagga ctaaacttga ttcccaattt ctccaactca cggatatccg agtcatcact
    45901 tggctgataa agggtaatag ctgtacctgg taggccattt cgtccagtac gaccaacacg
    45961 gtgaacaaaa aaagataagt cttgcggaat ggcatcattg atgacatggc tgacaccttc
    46021 aatgtcaatc ccacgcgctg ctaaatctgt tgcgacaata tactcaaaat ccagattttg
    46081 cacctgattc atgattcgct tgcgttcacg aggggcaata tcgccatgga tttttgcaac
    46141 cttcaagcct tgagcagtca gatatgaatg caattcatca gcacgcgttt tagtgttaac
    46201 aaaaatcatt gccaaatacg gctgcatcaa ctgagtcaac tggtaaattt gagcattctt
    46261 atcatgtccc ttggtcgaaa tcaaccaatt atcaatggtg tcagaaataa ccgttttggt
    46321 cttaattttc tccataacag gattggataa gtattttttc aagaatggtt gcagtttttg
    46381 tgggatagtc gctgagaaga ccatgaattg caagtctttt ggaagactgc cagcaatctt
    46441 atcaacagtt tccaagaatc ccatatccaa ggtcatatcc gcttcatcaa caacaaatgt
    46501 cttggcttta tgaatagcta aatcaccaga tttaaccaag tcgtagatac ggcctggtgt
    46561 tccaataaca atatgaggct gattgcttgc caatttctca atctggcgag ccttatccgt
    46621 accacccaca taattaacca cacgaacttc gacatctgag tgagctgaaa tctgacgcgc
    46681 tacttggtaa atttgagtag ccaactcacg actcggtgca gtaatcactg cttgtacact
    46741 atcgctagct tcatctaatt gctgaaaaat cggtaacaag aaagtatgag tcttacctga
    46801 acctgttttt gattctccta ctatgtcacg acctgccaaa acaataggaa tcaacttgtc
    46861 ttgcacctct gttggagttg taaattttaa ctccttcaag gcttctctaa tatagttttt
    46921 aaattgaaat ttcgtaaatg acataacatc ctcgattcta tctatcttat caattatacc
    46981 atattttatt ccattacagt agtctcactt atttaggcta tttccagtag cttctctagt
    47041 aagaaaaggc tggaatttta tagttccaac ctcttttcag ttattatttc cagtttaaca
    47101 tagcattcaa gccatagtga tcactcactt gtggactctt gttaccatca aatacgacat
    47161 gtaaattttc caccgctaac tctttggtag taaagacata atcgattcga aggggttcag
    47221 tgttcccttt ccagccatca atttcaggcg gaacagtata gctaccactt ttctcttgag
    47281 caacttcaaa tgcgtcttgt aagcctaatg gactagctaa aatagcttgg taaccttcct
    47341 gacctgctgg gttgttaaaa tctccagcta gtaaaagtgg cttgttcaat tttttcaaga
    47401 cagcctcaaa tcgtgcccat tcttcttgga aacctttatc ccaccaagag agatgaacac
    47461 tggcaactgc tagctccttg ccatcgacta cagtttcagc tagggcaaca cggcgagtat
    47521 gatagtctgt tggatcatcc acatctgaaa ccaaaatttc tctggcttca ataggtgttt
    47581 tagacaagat agccacacct tcgtggtagc ggtcatagcc gatatggtta taagcccagg
    47641 tccagtagta atttttccct tgctctaaca acttttcaac caagagtcta acataatggt
    47701 cttggtgaat aggctcagct gctggcaaag cttgataaag gtcattaacc tccacctctg
    47761 acgaggtcat ctcctgattg atttcttgga aacaaatcaa atcatagtcc ttttcaagaa
    47821 tatcttcaag caaaatctgg aatttttcct ctgcttcttt ctccatccaa ctgtgagtat
    47881 tgagtgttaa aaatttcatt cttttctccc aaaataagag gttggaatac agcttccaac
    47941 ctcaagtata ttacaattct actttagcaa ctgctgtttt agctgcaaga gaacctgttt
    48001 tttctaattt aactgattta attgcatcac catttgtgaa gacaactact gttgaagttt
    48061 cacgtcctgc tgcacggata gcattcaagt cagctgtgac aaggagatct cctgctgcaa
    48121 ctttttgtcc ttcagcaaca tgaactgtaa atggtttacc ttcaagactt actgtgtcca
    48181 aaccaatgtg aaccaatact tcaagacctg cttccgtcac aataccaaaa gcatgttttg
    48241 ttgggaagat gcttgataca gtacctgaaa ctggagatac aatgtttcca tttgcaggtt
    48301 ctactgcaaa tccatcaccc atcatttttt gagcaaatac tggatccttt acttgttcca
    48361 aagcaacaac ttgaccgtct gctactgagt aaacttcctc agtaagatct ttgaagtgaa
    48421 cagtgttttg ttgtgcttca gtcatttggc ttggaagagt ttcaggaatg atttcacctg
    48481 aatcaaggat atcttggata tcagatttca aaatgtcagc ttttggaccg tagatagctt
    48541 gaaccccttg tcctttcatc acaagaccca tagctccttc tgctttccat tgctctgcat
    48601 ttcctacttt atctgcatct ttaacagtta cacgaagacg agtcatacat gcatcaacat
    48661 caacgatgtt tacacgtcca ccaagaaggt tgataatgtt tacagcttga gagcctgctg
    48721 caactttcac ttcgctgctg gtttcttctg aaccttcagc agtttcgtag tttccgttgc
    48781 gccctggagt tgcgtagttg aatttttgaa tcatgaagtt tgcgataaag tacatgatta
    48841 cagcaaagag aacagttacc caaacgaagt taacgatatc cataccaata ccagcactga
    48901 ttgcaatagg tgtacgagtc aagaactcga ttgaaccgaa tgagtgcata cgtaggttta
    48961 cgacgtcagc catagcgaag gcagcacctt gaacaagtga gtaaacaaga tacataggtg
    49021 ttgcgatgaa catgaacatg tattcgattg gttcagtaac ccctgtcaag aatgttgcaa
    49081 gagctgttgc aatcatcata cctttgtatt tatgtttctt gtcagcatca acattacggt
    49141 agatagcaac aatcacaccc atcaagatac cgaatgaacc gatcatttgt ccaactttga
    49201 aacgagctgg atgtactgta tctaacaagt gttggtattg actagcatca gtacctttaa
    49261 ggtttacaag gtctgttacc catgcaagcc atagtgggtc ttgaccgaat acttgagtac
    49321 ctttagctgc accagttaaa atgtcataag taccaccaag agctgtgtag ttcattggga
    49381 tagtcaacat gtggtgaaga ccaaatggca agagcaaacg ttccaaagta ccatacaaga
    49441 atggtgcaag aattggagca gtttcttgtg agttggcaat ccagataccg aagttattga
    49501 tacctgtttg aactactggc cagaaagcag caagtagaat tgcagcgatt gctgaacgaa
    49561 gaataactac aaatggtacg aaacgtttcc cgttgaagaa tgaaagtgca tcaggaagtt
    49621 tacggaagtt gtagtatttg ttgtaagcag ttgcccctac aaaacctgag ataatcccta
    49681 cgaatacccc catgttcaag gctggagctt caagaacact gataaagtaa tcagcaactt
    49741 tgattgaacc accaaagaaa gtagttacca tagcatctgg atttttcaac atatcgcctg
    49801 atacaccaaa aattgtacca gtgatacggt taatcaagat gaaggcaaga ccagcggcga
    49861 aagcaccacc agcacgttct ttagcccagc ttcctccaat ggctagggca aacaaaatgt
    49921 gaaggttacc gataaccccc caaccgattt gctcaagaat tccacctgtg atgacaagtg
    49981 gtgtaaaggt tgggttaatc atcacgatag acttaccgat tgaaatcatc aaaccagcag
    50041 ccggcataac cgcgataact accatcaaag ccttaccgaa tttttgccaa aattcgaaag
    50101 acaagacatt tttgaatgta tctttcatca ttcaaatctc ctttattttt atttaggcaa
    50161 acgttttacg aaaacgtttg caccttctat gatttaatta taccacttta attttttttg
    50221 taaaggcttt tataaaaaaa ttacactttt ttctaaaaaa tttctagtgc gccaaatttc
    50281 aagttcaaat tagccatcaa gaagtcttct ctgggggact tctttggaag ctcttttctt
    50341 ctacgcatct cttttcaaaa actcttgtag caaaaaagga gattttacaa tctcctcata
    50401 aaagcagcta ttttacctaa atcctcaaga atcggcgcat ggatattcct gatcccaatg
    50461 aaccaatgaa aaccccaatc acaaatagta gggcaatcat caacggacta aataaatctg
    50521 gactaatcat ggatagattt tgccctacca acgatttgtt gacagattgg taaacaattt
    50581 gataaacaat aaagaccaaa acagatggtg cgatagctcc caataaaccg ataaaggctc
    50641 cttctaacaa gaacggtcca cggatataac tgtttttagc tccgaccaag cgcatgattt
    50701 gaatttcgcg actgcgggaa ataatggtaa tacgaatggt atttgaaatc aagaaaactg
    50761 cgataaaaat taacaaagca gcaatcccta gtccccaaac acggataaat gaagctaact
    50821 tgaagagtct ttctgtattg gcaccgccat cttgaacctc agagacacct tcaatttttt
    50881 tagcatcttc ggctatagtt tttacatcat ttggagtgtt tgcctctaca atataggcat
    50941 catagagagg attggcatct ccttcaaaga ttttccagtt atctcccatt atctcggtta
    51001 atttttcata ttgttcttct ttacttgaaa aggtaacact tttaaccgta gacatgttct
    51061 tcaaagaatc atataccttg tggtagtcat tatttgtaac agtttgacct tctttttcaa
    51121 ttgtctgact attatcttcc acatcctttc ggatataaac tactacacgg acattatttt
    51181 caatatctgt agctagtttc gctgtattga aaataacaga tgcaaatatt gccaccaagg
    51241 tcaaagtaat catgactgaa ctgacagcag ctactgtcat ccaaccattt cgtttcaaac
    51301 tttttaaggc ttcaaataaa tggcgaaaaa atctactaat catcgtatcc atactctcct
    51361 tttgattcgt cacgaacgac acggccattt tcaatggcaa tgacacggtg gcgcaaggta
    51421 tttacaatct ggctattatg agtcgccatc aaaatagttg tcccttgtag gttaatccgt
    51481 tccaagagat tcataatttc ccatgaatta tccggatcca gatttcctgt tggctcatca
    51541 gctatcaata ctttgggatt atttacaatt gcacgcgcaa tcgcaattcg ctgttgctcc
    51601 ccacctgaga gttcatttgg gaaagaacga accttatgct tcaatccaac caagtccaaa
    51661 acttccatca ctcgtctttt gatattacgg cgattttccc cgattacttc catagcgtaa
    51721 gcaatatttt catagacagt tttctttggt aacaatttat aatcttggaa gacaacccca
    51781 acactacgac gtagaagcgg gacatctttc tttttgatct taaccagatt aaaaccagca
    51841 actgatagac ttcctttatc gatttttact tcacgataca gagaacgaat aaaagttgac
    51901 ttccctgctc ctgaaggtcc tacgatgtaa gcaaattccc ccggttgaac gctgaccgaa
    51961 acaccgcgta gagcagtcgt tccgttgtcg tattttttaa cgacatctct catttcaata
    52021 attgacatgt gagttccttt ctatcttagc taattcgcca cttgagataa gcatcgataa
    52081 aaccatctag gtccccatcc ataaccttat ctacctgagc aacctcaaag ctagttcggt
    52141 gatcttttac catagtataa ggcgtgaaga cataagaacg gatttggctt ccccaagtga
    52201 tctccttttt ctcacctttg agagaatcta cctccgcagc cttcttatct tgctccattt
    52261 gatagagctt agcctgcaac atcttcatgg cacgatctct atttccatac tgggtacgat
    52321 ccactgttga ttggacaaca attccagttg gaatgtgggt taaacgtaca cctgttgaaa
    52381 ctttattgac gttttgtcca ccggcaccac ctgaacggaa ggtatccatc ttgatatcat
    52441 cttcacggat ttccacttca atagtatcat ccaattctgg catcacttct acagatgtga
    52501 aagaggtatg gcgacgtttg gcagagtcaa atggtgagat tcgcactaag cgatgaacac
    52561 ccatttctga cttgaggaga ccataggcat taggcccttc aaatgataaa gttaccgact
    52621 taataccagc ctcatcacct gcttggtaat ccaacacttc cactttaaag cctttagcat
    52681 taccataacg agtatacata cgaagcaaca tatcacccca gtcctgcgcc tcagtaccac
    52741 cagaacctgg atggatttcc aagatggcat tgttgtggtc ataaggttct gacaagagta
    52801 gagtcatctc gtagctggtc attatcttat caagttcggc taactgcgct accagttcat
    52861 catgcactga ctcgtcttca gccaaaaaat ccaataaaat ttcgacttca tcctgcaact
    52921 cttccatctt atggaaggta ttgtaagtgt tttttaattc atttaattct tgcgacgttt
    52981 tttgggccgc aatattatcg ttccaaaaat caggttctgt catcttgttt tccaagatgg
    53041 caatctcttc ctctagccct tcgaggtcaa agagaccccc tgaaagaagc taatttttca
    53101 cgatttgcgt caattttctg acgaattact gaaatgtcca taaatactcc ttttttacat
    53161 tatttcatta tagcatattt tatcatttct ttccatcttt ttctctaatc cccttttcat
    53221 gaaaaaagaa gcctttgggc ttcccttctt acaagacttt tgctgaagtg cgagcgattt
    53281 cttccacttg aataccattt gcttcaaatt tttctttcaa ggctggtaaa tcaattgatc
    53341 catcgatttg cacttcgata atcaccttac catccttacg cggaatattg actgtatggg
    53401 agatattcaa attttcttct acaatcaaag aaacaatttt tccaagaaca ccaacttcat
    53461 cttctgtaac aaagcgtaca cgaatccctt cttcgccata acctgcaatt tcaagaaagg
    53521 cttggaaaac gtcacggtca gtaataactc cgtatacttg atggttatct acgacaggga
    53581 gaatactaat cttatttttc aacatcagat aagttgcatc ttctagacta gcatagcctg
    53641 agacagtgac aacatcgcga atcatgacat cttttacttt tgtcttattc agaagataat
    53701 tcatctcata gatagaaaga cttgttgctt tagatggact tgcttgtgca atggttccct
    53761 cagtcaccaa accaactaat tgatcatttt cgataacagg cagacggtgc aaaccttgct
    53821 ctctcatcaa atctgctgca tgagatactg ttgtatctgg actaatataa actaccttgc
    53881 gggtcataaa atctttaact gccatgagac ttctcctttt ctattcttat ccctattata
    53941 caatcttttt gcaaatctat caaacgctta catttctttt tcgaaattca gaaaagtatg
    54001 aataagctag caaaagagct ctgaaatcga gttctgtgaa tgaaggtaag aaacttttca
    54061 ttcgattttt tcaattatta gaaattcagc tttcaatgta gatgcagatt tgtttgcaat
    54121 ctcaatctac cgactaaaaa ggtcccccgg actatattga tgattacttc gtaatcttca
    54181 tctgccgact aaaacaatcc actggattgt tttagccacc tagatatgct tttctgactt
    54241 cttctgatga ggcgagttct tttcctgttc ctgataggac gattttccct gtttccagta
    54301 catatcctcg gtcagagatt gcgagtgctt tattggcatt ttgttcaatc aagaggacgg
    54361 ttgttccttg cttctgaata tcttgaatga tatcaaaaat ctcttggata aagattgggg
    54421 caagtcccat tgatggttca tctaaaagaa gaagttttgg tgttgacata agagcgcgtc
    54481 ccatggcaag catttgttgt tcccctcctg aaagagtagc tgcatcttgg ttcttacgtt
    54541 cttcaagacg aggaaagcgt gagaaaacct tcttcaagtt tgcttgattt tcttcacgat
    54601 ttttctttaa gaaagctccc atttcaagat tttccataac agtcaagcca ggaaagacgt
    54661 ggcgtccttc tggaacttgt gaaagaccac ctgccacgat tttctgagct ggcatttttt
    54721 ggatttcttg acctaaaaat tcaatctttc ctgaacttgg tcgaaccaaa cctgacaagg
    54781 tgcgaagaat agttgtctta cctgcaccgt tggcaccgat aagggaaaca acttctcctt
    54841 cattaacttc aaagcttaca tcacggactg cttggatcat accgtaatgc acagaaagat
    54901 tttcaacttt taacatagac attaggcttc acctcctaga taagcttcga taacgcgttt
    54961 attggtctta atttcgtctg gagttccttg agcaattaaa cggccatatt caagtacgta
    55021 gatacgttct gttacttcca tgaccagatt catatcgtgt tcaatcaaca tgattgtaat
    55081 cttaaattca tctttgatac gacgaattaa ctcagtcaat tcggctgttt cctgtgggtt
    55141 catacctgct gctggttcat ctaagaagag aattttaggt tccgtagcaa gggcacgaac
    55201 aatttccaaa cgacgttgtt gtccgtagga aagattttta gcaagagtct ctgcatcacc
    55261 atctaaatca aagattttca acaattccaa agctttatcc tttaattctt tttcactctt
    55321 gtaaaaagct ggtaagcgta agaaactagt aaaaacatgc tgtttgtgat ggtttccaaa
    55381 agcaatcaaa acattatcta aaactgttaa atctttaaag agacggatat tttggaaagt
    55441 acgtccaagt cccaaagagg caatcttata aggtgatttc ccattcaaaa ggtgaccatc
    55501 tagggttact gttccctcgc ttggttcata aacaccggtc aaaaggttga aaagggtggt
    55561 tttcccagct ccgtttggac cgattaatcc aaccagttcc ccttcgttca attcaagagt
    55621 cacatctcca acagctgtta gaccaccaaa atgtttggtt aactgtttta cttcaagtaa
    55681 tgccattagt tttgttcctc cttcttagat tttttaaaga aacgtgatag gctcagttcc
    55741 catgttccaa ggagtccacc tggtctgaaa atcattacca ataccaaggc caaagcgtaa
    55801 ataatcatac gcacactagc aacatcttgg agaagcatat tcaaaattcc cagaacaata
    55861 gccgaaacaa tcgcacctgt aatggaaccg agtccaccaa atacaacaat aatcaaaacg
    55921 ttgattgagt tgatgaaggt gtaatctttc ggtacaacag acccgataaa tcctgcctga
    55981 agtgacccag caatacttgc agtaatggca ccaaagacaa aagcgatgat tttaatttta
    56041 gtcgtattaa ccccaactga ctcagcagcg atttcatctt cacgaacaga gagggttgaa
    56101 cgaccaattg ggctacgcaa gaagttcaag gttgcaatgg ttgtaatcac gacaaagaag
    56161 taaaccattt gccaagttgt aaagttagga atccctaaaa tacctgccgc accatttgta
    56221 aggcttccac cattgatgat aaagatacgg ataatttcag aaacacctag agttgctacc
    56281 gcaagatagt cccccttcaa gcgcaaggtt ggaatgccga caagtaaggc aactgctcct
    56341 gaaagcaaag ctcctacaag catagctcca aagaaggcac cgtaggttgg tgatttagaa
    56401 ccaataatag ctgctgcata ggcaccaatc gccatgaaac cagcatgacc aagtgaaaat
    56461 tgtcctgaaa aaccaacgat taagttgaga ccaacagcca aaataatatt aattccaatt
    56521 tgttgtaaaa tctgtacata gaatagatta agtactccga ctgaaaccag tacactaatc
    56581 aagctatagc cagctaacaa aaggagtaac catagaatat taacttttaa attttccttc
    56641 atcgcttaca ccttctcttt cacattctta ccaaggatac cagctgggcg gacaatcaag
    56701 atcaacaaca agattccata aacaatggca tcacggaaat ctgacatccc aaaggctgtc
    56761 gcaaaggttt ccaatagacc aatcacaaag ccaccaagag ccgcaccagg aataattccg
    56821 ataccaccaa gtactgcggc aacgaaagat ttaagacctg gagtaacccc catcaaaggc
    56881 tcaagagagt tataataaag agcaatcaga acaccagccg cacccgcaag agcagaaccc
    56941 aaagcgaagg taaagctaat cgtacggttt acattgatcc ccatcaattg cgccgcgtcg
    57001 ctatctactg atactgcacg catggctttc cccatcttag tcttttggac aatgacttgt
    57061 aacaaaatca tcaaaatcaa ggaaatagcc aaaatcatta actgcacatt tgttaagcta
    57121 attggtccca aatcatatcg aactgtttga atcgcttgag ggaaggcacg ggtattggca
    57181 ccaaccagat agaccattcc atactccaat aggaaagaaa ccccaatagc cgtaatcaaa
    57241 acagcaatac gagtagagtg gcgcaaaggt cggtaagcaa gaaactcaat cacgacacca
    57301 agaatagctg tcgctagcat agctacaata agcgctacaa agaaattcat ttggaaagaa
    57361 ttgatcaaga aataaccgat aaaggctccc atcatataaa tatcaccatg ggcgaagttg
    57421 atgagcttga taattccgta aaccatggta tatcctaggg ctaacagcgc gtaaacacta
    57481 cctagaatca aaccatttac gagttgttgg agcataagat tcactctttc tatttataat
    57541 tccgagggtt ttccctcact ttttgatagg ttcttatact caatgaaaat caaagagcaa
    57601 actaggaaac tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac
    57661 gaagtcagtc acatatataa tccaaggcga cgttgacgca gtttgaagag attttcgaag
    57721 agtattaaat atcgaaacag ggagtgagtc aaaggctcat tccctatttc aacatttttc
    57781 tattatggtt ttacaacttc tgctgcttca actttaccat tgttcatggt catcatgtaa
    57841 gcagttttga ctgtgttgtg gtctgcatcg aagcttgttt gaccagttac accttcaaaa
    57901 tcttttgttt tagcaaggtt atccttgatt tcacctgaat ttttagcacc ttttgctgcg
    57961 tttgctacaa ggtgaactga atcataagcc aaggctgcaa atgttgaagg ctcttcattg
    58021 tacttagcac ggtaagcgtc aaggaaggct ttagctttag ctgaaacttc tacagtagtt
    58081 gagaagcctg agataaagta gatgtttgat gctttttcag cagttgcttg ttgtacaaac
    58141 tcctcaccgt tgaatccatc accaccaacg attggtttgt caattcccat gccacgcgct
    58201 tggtttacaa tcttaccagc ctcattatag taaccaggaa caacgatagc atcaaagtct
    58261 ttccctttca tttttgtaag ggctgcttgg aagtctgtgt cacctgctac gaaagtttca
    58321 tctgcaacga tttcaccctt gtatgactcg cggaaagatt tggcaatccc tttagcatag
    58381 tcactggcat tgtcagtgta aagaacaact ttcttagcat ttaatttttc agaaacatag
    58441 tttgagataa tttttccttg gaagctatct tggaaagttc caataaagag gtaatcttga
    58501 cctttagtca atccatcttg agtcgcactt ggtgagatca atggaacacc tgcttttgta
    58561 gcgttcgcta ccgcagctgc agtcgcacca gatgtcgcag gtcctacgac tgctgatact
    58621 ttagattggg ttacaaggtt agttgtaact gaagcagcct cagctgtttc agacttatta
    58681 tctttatcga ctacttcgat ttgttttcca tcgataccac ctgcggcatt gatttcatca
    58741 acagccaatt gggcaccttt ttgttcagct gttccgtatg cagctaaaga acctgattct
    58801 tcaaagttaa acccgatttt aattgtcttt tcctctactg agttaccagc agtgttgact
    58861 gctccagact tcacttctcc acaggctgca agaagtgcta cacttgcaag cgccacaaac
    58921 gatagggcaa attttttctt catctttttg tctccttatt tcttaaatag tctgttaaga
    58981 atataccgaa ttatcagaaa attgtcaatg ttttccttga gcttttttcg atgataacgt
    59041 tttcctatcg ataaagattg cccacaaagg gtgtttccaa ctcttggata tgacaaaccc
    59101 taactttttt aataaatttt tccttgctca agcgtccgac caattgctcc acttcttgag
    59161 ttggaacata gagttgtaag taacgatgtt tcttggaatg ataggtaata tctccataat
    59221 cctgcagttt tttggcatca cgattatagt aaagatagat aatcaagcca gagcgattga
    59281 ctttttcaaa catgataaat cctctttcta agaaatctct ccctattata ccaaaaaaag
    59341 caaacccagt cgagtttgcc ttctatcatc attagttcaa tgaattgttg gccataattt
    59401 catcaataaa gccatattca agtgtttcct gggcgctcat ccagttatca cgttctgcat
    59461 ctgcatggac tttttccatt gactgacctg aattttcagc caagattttt tccaaggtat
    59521 tacgagtttt gagcaagtgt tctgcagcga tagccatatc agtttgttgg gtaccaccac
    59581 ctgtaccgcc cattggttgg tgaatcatgt attcagcatt tggaagcatg aaacgtttgc
    59641 cttttgcccc acttgatgcg atgacagtcc ccatagatgc agccattccc ataacaatgg
    59701 tttggacatc tgccttgata aagttcatgg tatctacgat tgccaaacca gctgaaacag
    59761 aaccacctgg tgtattgaca taaaggtaaa tatcttttgt actatcttgg gcatccaaga
    59821 aaagcaattg ggcaataaca gagttagcca tattgtcttc aaccggacct gtcagcataa
    59881 tgatgcggtc tttgagaaga cgtgagtaaa tatcgtaaga acgttctcca cggcttgttt
    59941 gttcaataac tacaggaatc attcatttct ccttttgagt tttaattttg ttggtcaaat
    60001 gactgaagat aagactatta taatatcttg gtcaaaaaag gtcaaatttt tgctctgctt
    60061 tcattagaca gaaacaaaaa cccaacctcc tttcgtgact ggaaatactt ttccaagtca
    60121 ttcttctttt cgatcttatt ttgtaccgaa caagcggtct ccagcatctc caagacctgg
    60181 aacgatataa ccgtgttcgt tcaaacgttc atccaaggct gctgtaaaga tttctacatc
    60241 tggatgagct tcttgaaggg cttttacacc ctctggagca gatacaaggc agacaaattt
    60301 gatatttgat gcgccacgtt ttttaagaga atcaacagcc aagattgctg agccacctgt
    60361 tgccaacatt gggtctacta caaaaatttg acgttggtca atgtcctcag gcaatttcac
    60421 caagtattca actggttgaa gtgtttcttc atcacggtac ataccgatgt ggccaacttt
    60481 agcagctgga accaagctca agagaccatc aaccatcccg atacctgcac gcaagattgg
    60541 gacgatggcc aatttcttac ctgccaattg tttttgaact gtttttgtaa ttggtgtttc
    60601 gatttccaca tcttctagtg gaagatcacg aagtacttca taccccatca acattgcaat
    60661 ctcatctact agctcacgaa aagcttttgt agaagtatct gtacgacgca agattgacaa
    60721 tttgtgttga atcagtgggt gattaataac ttcaattttt cccatttttg gaattccttc
    60781 tttcaattta ttcttcttat tataccaaaa aacggtttaa aaatctttct aaaccattta
    60841 tttttgataa tttttacatt agatcagcct ctttaagagc tgtctgtact gtctcaagtg
    60901 gtaaatgggt caattctgtc cctttttctt gataaaggta ttgggcgtag tcgtccattc
    60961 ggtactggtt gatataaacc acacgcttgc agccgacctg aagcaattgt tttgtacagt
    61021 tgagacaagg aaaatgggtt acataggctg taaagccttt gggaacacca cgctcagcac
    61081 cttgaaggat agcattgacc tcagcgtgaa gggtgcgaac acagtggcct tcaatgacca
    61141 aacattcgtg atcaatacaa tgctcagtcc ctgacaccga accattgtaa ccagtggaaa
    61201 taaccttatt atcttttacc agaatcgcgc ccactttagc acgtttacaa gtggaacgat
    61261 tcgcaattag tagggcttgg gctgcaaaat actcatccca ggccagtctt ttttcagtca
    61321 tctcttttct cctttttctc tattttttaa aaaatggtaa acctaaatct gcaatctttt
    61381 cagctggtac cttcatgcca tccttgatcc attttagaag gacagagacg atggctgagc
    61441 tccagaagga atgaagataa gagctgacac cttttgattt cccatggtat ttttctagaa
    61501 attcctgcat ggcttggaca aagatttttt ccagatggta atccaaggcc aattgaatca
    61561 ctctagcttc ctttctggcc tcccggaaaa ggtgaaccca aaccaaataa aggtctgtct
    61621 ttaaatcgta atgatgcagc tgttccataa tattgtggac agttcgttta aagacgctct
    61681 ctaaaatttc ctctttggag tcataattgc gataaaaggc cgcacgcgaa acacctgcac
    61741 gtttgaccaa ttcagaaata ctaatcttgg tcagttcctt tttttccaag agttgcaaga
    61801 gggctgtttc aatggcttct ctggttaata aattggattc ttggtttgat tttctgagat
    61861 tttcaagaga cttttcagag attctacgtt cagacataac attttctttc tacttgtcac
    61921 aacagacgga tgatgctttt gtttcaaggg ttttcatgat ataattgtaa aaaaagacag
    61981 aacctttgtc aatgtataac tgacaaagat ggagaatttc tatgacttgg aagattattg
    62041 ctgactctgg ttgtgattat cgtcaactgc caacaccagc tattaacaca acctttgtaa
    62101 gtgtcccctt aaccattcaa gtagctgatc aggtctttgt tgatgacgcc agtctcgata
    62161 ttgaccaaat gatggaaacc atgtatgcaa ctgcagaagc ttcaaaatcg gcttgtccaa
    62221 gcccagatga ctatttgcga gcatttgaag gtgccaaaaa cattttccta gtaaccatca
    62281 caggtaccct ttctggcagt cacaatagtg ctcaactagc aaagaatatt tatctggaag
    62341 accatcctga cactaagatt catgtgattg atagtttatc tgctggtggt gaagttgacc
    62401 tactcgtaga aaaattgaat gacttgattg accagggctt gtcttttgaa gaagtggttg
    62461 aagctatcac cgcctatcaa gaaaaaacta agttgctctt tgtcctagcc aaagtcgata
    62521 acttggtgaa gaacggccgt ttgagcaagc ttatcggtac ggtcgttggc cttctcaaca
    62581 ttcgtatggt cggaaaagct agtgaaactg gaactctcga attgctacaa aaagcaaggg
    62641 gatcaaagaa atcagttcaa gctgcctatg atgagttagt aaaagctgga tatgctggtg
    62701 gccgtattgt catggcccaa cgcaataacg aaaaatgttg tcaacagctc tcagagcgaa
    62761 tccgtgaaac cttcccacaa gcggatatta aaattctacc aacctctggt ctctgcagtt
    62821 tctatgcaga agagggcggt ttgctgatgg gctatgaaat tgattaattg cattcttgac
    62881 aagaggtgac catcatctct tgtttttttg tggtacaata gagctatgaa acattttgat
    62941 actattgtca tcggtggggg acctgctggt atgatggcta cgatttccag tagcttttat
    63001 ggacagaaaa ccctcctcat cgaaaaaaat cggaaacttg gaaaaaaatt agctgggact
    63061 ggtgggggac gttgcaatgt gaccaacaat ggtagcttag acaacctgct agctggaatt
    63121 cctggaaacg gacgctttct ttacagtgtt ttctcccagt tcgataatca tgacatcatc
    63181 aactttttta cagaaaatgg tgttaaactt aaggtcgaag accacggacg cgtctttcca
    63241 gccagtgaca agtctcggac tattatcgaa gctttggaaa agaaaatcac tgaactaggt
    63301 ggtcaagttg ctactcaaat agaaatcgtt tctgttaaaa aagtagatga ccagtttgtc
    63361 cttaagtcag cggatcaaac cttcacttgt gagaaactca ttgtcacaac aggtggtaag
    63421 tcttatcctt cgactggttc gactggtttt ggtcacgaga ttgctcgcca ttttaagcat
    63481 accatcaccg agcttgaggc tgctgaaagt cctttattaa cagattttcc acataaagcc
    63541 ttacaaggga tttctttgga cgatgtgacc ctaagttatg gtaagcatgt catcactcat
    63601 gatttactct ttacccactt tggtttgtca ggtcctgctg ccctacgcat gtctagcttt
    63661 gtcaaaggtg gggaggttct ctcactcgat gttttgcctc aactttctga gaaggacttg
    63721 gttacatttc tagaagaaaa tcgggaaaaa tccttgaaaa acgctttaaa aaccttgtta
    63781 ccagaacgct tggccgaatt ttttgtacaa ggatatcctg aaaaagtcaa acagctgact
    63841 gaaaaggaac gagaacaact tgtccagtcc attaaagaac ttaaaattcc tgtaactgga
    63901 aaaatgtccc ttgcaaagtc ctttgttacc aagggtggag tcagtctcaa ggaaatcaat
    63961 cctaaaaccc ttgaaagtaa gctggtacct ggcctccact ttgcaggcga agttatggat
    64021 atcaatgccc acacgggtgg ctttaacatc acttctgctc tctgtaccgg ctgggtggcg
    64081 ggatcaaatc caatctaaat atacattact aaatggaaca atccccccaa aaaaagaaag
    64141 gaactacttt ggaacatatt atcttgctaa ggggagtcac tcctaatgga aaaaatgcta
    64201 tccctaaaat gtcttatcta gtagatatct tgacagaagc tgattttcaa caagttcgaa
    64261 cttatattca aagtggaaat attattcttg aaagtaactt agctctcgaa gaaatacgag
    64321 aacaggttca tactctatta gacttcctgt gaaacta
//
LOCUS       DAVDHC010000011        61501 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVDHC010000011 DAVDHC010000000
VERSION     DAVDHC010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 61501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.011"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..273
                     /locus_tag="VUR43_000950"
     CDS             <1..273
                     /locus_tag="VUR43_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5412655.1"
                     /translation="PEKPKPEVKPQPEKPKPDNSKPQADDKKPSTTNNLSKDKQPSNQ
                     ASTNEKATNKPKKSLPSTGSISNLALEIAGLLTLAGATILAKKRMK"
     gene            complement(492..1472)
                     /gene="dusB"
                     /locus_tag="VUR43_000951"
     CDS             complement(492..1472)
                     /gene="dusB"
                     /locus_tag="VUR43_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET5412656.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKV"
     gene            complement(1459..2331)
                     /gene="hslO"
                     /locus_tag="VUR43_000952"
     CDS             complement(1459..2331)
                     /gene="hslO"
                     /locus_tag="VUR43_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET5412657.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2496..3923
                     /locus_tag="VUR43_000953"
     CDS             2496..3923
                     /locus_tag="VUR43_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5412658.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRYYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4082..5590
                     /gene="glpK"
                     /locus_tag="VUR43_000954"
     CDS             4082..5590
                     /gene="glpK"
                     /locus_tag="VUR43_000954"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET5412659.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGIKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGATHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAMLPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5632..7458
                     /gene="glpO"
                     /locus_tag="VUR43_000955"
     CDS             5632..7458
                     /gene="glpO"
                     /locus_tag="VUR43_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET5412660.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSGKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7528..8232
                     /locus_tag="VUR43_000956"
     CDS             7528..8232
                     /locus_tag="VUR43_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET5412661.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8529..8732
                     /locus_tag="VUR43_000957"
     CDS             8529..8732
                     /locus_tag="VUR43_000957"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412662.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8819..9079)
                     /locus_tag="VUR43_000958"
     CDS             complement(8819..9079)
                     /locus_tag="VUR43_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412663.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(9134..9478)
                     /locus_tag="VUR43_000959"
     CDS             complement(9134..9478)
                     /locus_tag="VUR43_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412664.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENDSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            10514..11791
                     /gene="ltrA"
                     /locus_tag="VUR43_000960"
     CDS             10514..11791
                     /gene="ltrA"
                     /locus_tag="VUR43_000960"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET5412665.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKFLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRHKTLVGTPQGGNLSPLLSNVMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSASRFIEKRLGLKVNMTKAKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     RIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVSQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            12248..13426
                     /locus_tag="VUR43_000961"
     CDS             12248..13426
                     /locus_tag="VUR43_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5412666.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            13740..13871
                     /locus_tag="VUR43_000962"
     CDS             13740..13871
                     /locus_tag="VUR43_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET5412667.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            13892..15442
                     /gene="dltA"
                     /locus_tag="VUR43_000963"
     CDS             13892..15442
                     /gene="dltA"
                     /locus_tag="VUR43_000963"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET5412668.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDSVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15439..16683
                     /gene="dltB"
                     /locus_tag="VUR43_000964"
     CDS             15439..16683
                     /gene="dltB"
                     /locus_tag="VUR43_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET5412669.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            16697..16936
                     /gene="dltC"
                     /locus_tag="VUR43_000965"
     CDS             16697..16936
                     /gene="dltC"
                     /locus_tag="VUR43_000965"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET5412670.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            16929..18197
                     /gene="dltD"
                     /locus_tag="VUR43_000966"
     CDS             16929..18197
                     /gene="dltD"
                     /locus_tag="VUR43_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET5412671.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18352..18792
                     /gene="adcR"
                     /locus_tag="VUR43_000967"
     CDS             18352..18792
                     /gene="adcR"
                     /locus_tag="VUR43_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET5412672.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            18792..19496
                     /locus_tag="VUR43_000968"
     CDS             18792..19496
                     /locus_tag="VUR43_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET5412673.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19489..20295
                     /locus_tag="VUR43_000969"
     CDS             19489..20295
                     /locus_tag="VUR43_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET5412674.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20305..21810
                     /gene="adcA"
                     /locus_tag="VUR43_000970"
     CDS             20305..21810
                     /gene="adcA"
                     /locus_tag="VUR43_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET5412675.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYHTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(22970..23743)
                     /locus_tag="VUR43_000971"
     CDS             complement(22970..23743)
                     /locus_tag="VUR43_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5412676.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            23919..25322
                     /locus_tag="VUR43_000972"
     CDS             23919..25322
                     /locus_tag="VUR43_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET5412677.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            25437..26075
                     /locus_tag="VUR43_000973"
     CDS             25437..26075
                     /locus_tag="VUR43_000973"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET5412678.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            26087..26530
                     /locus_tag="VUR43_000974"
     CDS             26087..26530
                     /locus_tag="VUR43_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET5412679.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENVQ"
     gene            26520..26951
                     /locus_tag="VUR43_000975"
     CDS             26520..26951
                     /locus_tag="VUR43_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5412680.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            26942..27412
                     /locus_tag="VUR43_000976"
     CDS             26942..27412
                     /locus_tag="VUR43_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5412681.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27437..28210
                     /locus_tag="VUR43_000977"
     CDS             27437..28210
                     /locus_tag="VUR43_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET5412682.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            28207..29007
                     /locus_tag="VUR43_000978"
     CDS             28207..29007
                     /locus_tag="VUR43_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5412683.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            29066..31360
                     /locus_tag="VUR43_000979"
     CDS             29066..31360
                     /locus_tag="VUR43_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET5412684.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTVFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31370..34486
                     /locus_tag="VUR43_000980"
     CDS             31370..34486
                     /locus_tag="VUR43_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET5412685.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPISCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            34543..36309
                     /locus_tag="VUR43_000981"
     CDS             34543..36309
                     /locus_tag="VUR43_000981"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET5412686.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMFPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRS
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYCACQLLGPLHK"
     gene            36455..37606
                     /locus_tag="VUR43_000982"
     CDS             36455..37606
                     /locus_tag="VUR43_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET5412687.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKALKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            37751..38635
                     /locus_tag="VUR43_000983"
     CDS             37751..38635
                     /locus_tag="VUR43_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET5412688.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            38989..39240
                     /locus_tag="VUR43_000984"
     CDS             38989..39240
                     /locus_tag="VUR43_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET5412689.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGAQPVQATE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            39228..39518
                     /locus_tag="VUR43_000985"
     CDS             39228..39518
                     /locus_tag="VUR43_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412690.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQTEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQKLMNKAVKDEVAQI"
     gene            complement(39701..39828)
                     /locus_tag="VUR43_000986"
                     /pseudo
     CDS             complement(39701..39828)
                     /locus_tag="VUR43_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(39922..41253)
                     /locus_tag="VUR43_000987"
     CDS             complement(39922..41253)
                     /locus_tag="VUR43_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET5412691.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGIKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVKLLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPEAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(41275..42786)
                     /locus_tag="VUR43_000988"
     CDS             complement(41275..42786)
                     /locus_tag="VUR43_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET5412692.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(42995..43942)
                     /gene="arcC"
                     /locus_tag="VUR43_000989"
     CDS             complement(42995..43942)
                     /gene="arcC"
                     /locus_tag="VUR43_000989"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET5412693.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(44107..45123)
                     /gene="argF"
                     /locus_tag="VUR43_000990"
     CDS             complement(44107..45123)
                     /gene="argF"
                     /locus_tag="VUR43_000990"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET5412694.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(45181..46410)
                     /gene="arcA"
                     /locus_tag="VUR43_000991"
     CDS             complement(45181..46410)
                     /gene="arcA"
                     /locus_tag="VUR43_000991"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET5412695.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVISKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            47166..48845
                     /locus_tag="VUR43_000992"
     CDS             47166..48845
                     /locus_tag="VUR43_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET5412696.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     EPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            complement(48885..50969)
                     /locus_tag="VUR43_000993"
     CDS             complement(48885..50969)
                     /locus_tag="VUR43_000993"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET5412697.1"
                     /translation="MKPLLETIDTRFGTTNKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTGQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEGGDWRIDLVSSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKASAQADWENLLHRFDVIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            51140..52420
                     /locus_tag="VUR43_000994"
     CDS             51140..52420
                     /locus_tag="VUR43_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET5412698.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFVELDLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            52511..55156
                     /locus_tag="VUR43_000995"
     CDS             52511..55156
                     /locus_tag="VUR43_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET5412699.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKDHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMCSENVRVPESQHLFLDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            55239..56108
                     /locus_tag="VUR43_000996"
     CDS             55239..56108
                     /locus_tag="VUR43_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5412700.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            56102..57982
                     /locus_tag="VUR43_000997"
     CDS             56102..57982
                     /locus_tag="VUR43_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HET5412701.1"
                     /translation="MVRFTGLSLKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEILALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDVTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            58134..58343
                     /locus_tag="VUR43_000998"
     CDS             58134..58343
                     /locus_tag="VUR43_000998"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412702.1"
                     /translation="MKQKNYLVSNATVRQTYDKIAESECFLRAIGGIMLHLKLVKQEI
                     EAEKPASVEAWIISVKFKKGCYRHI"
     gene            58344..58706
                     /locus_tag="VUR43_000999"
     CDS             58344..58706
                     /locus_tag="VUR43_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412703.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFRS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(58758..59571)
                     /locus_tag="VUR43_001000"
     CDS             complement(join(58758..59192,59194..59571))
                     /locus_tag="VUR43_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET5412704.1"
                     /translation="MKKTLTPTKESIDSLRNYEASKQLTDTRFKRLVGVQRTTFKEML
                     AVLKTAYQLKHAKGGRKPKLSLEYRTYEEIAADFGIHESNLIRRSQWVEVTLVQSGVT
                     ISRTPLSSEDTVMIDATEVKINRPKKELANDSGKKKFHAMKAQAIVTSQGRIVSLDIT
                     VNYCHDMKLFKMSCRNIGQAGKILADSGYQGLMKICPQAQTSRKSSKLKPLTAEDKAY
                     NHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLVAGIINHELGF"
     gene            complement(59516..59698)
                     /locus_tag="VUR43_001001"
     CDS             complement(59516..59698)
                     /locus_tag="VUR43_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5412705.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            60033..>61501
                     /gene="pcpA"
                     /locus_tag="VUR43_001002"
     CDS             60033..>61501
                     /gene="pcpA"
                     /locus_tag="VUR43_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET5412706.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSMATGWVKDKG"
BASE COUNT        18681 a        11212 c        13384 g        18224 t
ORIGIN      
        1 ccagaaaaac caaaaccaga ggttaaaccg cagccggaaa aaccaaaacc agataatagc
       61 aagccacaag cagatgataa gaagccatca actacaaata atttaagcaa ggacaagcaa
      121 ccttctaacc aagcttcaac aaacgaaaaa gcaacaaata aaccgaagaa gtcattgcca
      181 tcaactggat ctatttcaaa tctagcactt gaaattgcag gtcttcttac cttggcgggg
      241 gcaaccattc ttgctaagaa aagaatgaaa tagtgattga ttcattcaaa aatgtttgta
      301 aaaagtattc ggcttaaaag aaaagagtct gggataaaaa gattttgatt ttaggaattc
      361 tttattataa atttttaaaa tcgatagatt agacaaaaaa gcgaacaaga cagaattctg
      421 agtgtcagat aactgatttt gttcgctttt tatatttaat attatacttt tgtcctaggc
      481 tcttttttgc actatacttt ttccaattgc aagagggctt caatctctgc cagggtgcta
      541 gcttgcgaaa tggctccacg gagtttggca gcgccagatg ttccccggag atagtgagga
      601 gcgaggccgc ggaattcacg aactgcgacg ttttctcctt tgaggttaat caatcgtttc
      661 aagtgttcgt aggcgatctt catcttgtct tcaaaggtca aatcaggtag gatttctcct
      721 gtttcaaagt aatggttgat ttggttgaag aggtaaggat ttcccatggc agctcggcca
      781 atcatgactg cgtcagcacc aacttcttcg atgcgttgct tggcttcttg gacagtacgg
      841 atatcaccgt tggcgatgaa tggaatcttg gttagagctt gggcaacctt gtaaagggtc
      901 tcaaggtctg cgtggccagt atacatttgt tcacgggtac ggccatgcat ggcgagggca
      961 gaaacacctg cagcctcagc agcgagggca ttttctactg caagagatgg gtccgcccag
     1021 ccggtacgca ttttgacagt aagtgggata tcaaggacag actggacctt gttgatgata
     1081 gagtagatct tgtcaggatc cttgagccac atagcaccag cttcgttctt cacgattttg
     1141 ttgacagggc agcccatgtt gatatcgacg atatcggtct tggtattttc ttggatgaat
     1201 tctgctgcgc gtgctaggct gtcttcatcg ctaccaaaaa gttggataga gacagggttt
     1261 tcgccctcat cgatatgaag catgtgcagg gttttttcgt tgttgtattg gattcccttg
     1321 tcagagacca tttccattac aacgagtcca gctccgagct cttttgcgat ggtacgaaag
     1381 gctgagttgg tcacgccagc cataggcgct aaaacggtac gattgggaat ctcaatattg
     1441 ccaatcataa aaggtgtatt aagatttgtc acgaatgagt tcctccaggt ccttttcatc
     1501 aaagttgtaa gtagtttggc agaattgaca agtgatttct gccccgtggt cttcctcttt
     1561 catttcctgt aagtctgagc ttggaaggct ggcaagagcg ttcataaagc gttcatggct
     1621 acagtcacat tggaaacgga tttcttcttc agaaagacgc ttgtaggctt cgtccccgta
     1681 gatagccttg aggagggctt cgatatggtc gtcgctttcg agaagagtag agatagctgg
     1741 catttcttgg atgcgttttt caaagcgagc aatctcttct ttcttggctc ctggcaagac
     1801 ttgaactagg aaaccacctg caaccttgac cttgtcttcc tcgtccaaaa ggacattgag
     1861 gccgaccgct gaaggcgttt gttggctttc agtaaggtaa aaggcaaggt cttcaccgat
     1921 ttctccagag atgaggggag ttatagagtt gtaaggattt ccagtaccgt agtctgtgat
     1981 aacgaggaat tgaccatttc caacaaaagg tccgactagg acttcaccag tcgcagtctt
     2041 tttgatgtca acaccaggat tttgaacata gcctttgacg ttccccttgg tatcagcgac
     2101 ggtgataata gcacctagag agctagagcc caacacctta actgtaagtt tggtatttcc
     2161 tttttcattg gctgcgagaa tctggctggc gataagagtt cgaccaagcg ctacagttga
     2221 gctagcttgg gtttgatgtt tttcttgagc agtgcggacg gtttccgtgc tatcaaggac
     2281 aaaagcacga aaggctccgc tttctgatat agttttaata attttatcca tagctactat
     2341 tttagcataa aaatgcccaa agggggagcc gtgtgtttac tgattttcag gataatggac
     2401 caggaaatca gcatgaaaat aaaaagagaa acagattatt ttagcatttg taagatttat
     2461 gctatgctta aggtagaaaa tgaaagggat aacaaatgta tttaggagat ttgatggaga
     2521 aagccgagtg tggtcaattt tcaatccttt cctttctatt acaagagtct cagacgaccg
     2581 tcaaggctgt aatggaagaa acaggatttt caaaagcaac cctaaccaaa tatgtcaccc
     2641 tgctcaatga caaggctttg gatagtggct tagaactgac tattcactca gaagatgaaa
     2701 atctgcgtct gtctatcggt gcagctacca aggggagaga tattcggagc ttgtttttgg
     2761 agagtgctgt taaataccag attttggttt atcttctcta ccaccaacag tttttagccc
     2821 atcagctggc tcaagaattg gtgattagcg aggctacgct tggtcgtcac ttggctggtt
     2881 taaatcagat tttgtcagaa tttgatttat ccatccaaaa tggacgttgg cgaggtccag
     2941 agcatcagat tcgctatttc tatttctgtc ttttccgaaa ggtctggtcg agtcaggaat
     3001 gggaaggtca catgcagaaa ccagagagaa aacaggagat tgccaattta gaggaaatct
     3061 gcggtgcaag tttgtctgtg gggcagaaat tggacttggt tctctgggct cacatcagtc
     3121 aacaacgtct tcgggtcaat gcttgtcagt ttcaagtcat agaagagaaa atgcgagggt
     3181 attttgacaa tatcttttat cttcgtttgc tgagaaaggt tccgtccttt tttgctgggc
     3241 aacatattcc actaggagtt gaggatggtg agatgatgat attcttctct tttctcctat
     3301 ctcatcgcat tcttcctctt catactatgg agtatattct tggttttgga gggcagttgg
     3361 cagatttact gacgcaattg attcaagaaa tgaagaagga ggaactattg ggggattata
     3421 cagaggacca tgtcacctat gaactcagtc agctttgtgc tcaagtctat ctttataagg
     3481 gctatatttt acaggatcgc tacaagtacc agttagagaa tcgtcatcca tatttactga
     3541 tggaacatga ttttaaagag acagcagagg agatttttca tgctctgcct gcttttcaac
     3601 aggggacaga tttagataag aagattctct gggaatggct ccagttaatc gaatatatgg
     3661 ctgaaaacgg tggccagcat atgcggattg gtctggattt gacatctggt tttcttgtct
     3721 tttcaaggat ggcagccatt ttgaaacggt atttggaata caatcgtttt attaccattg
     3781 aagcttatga ccctagtcgg tattatgatt tgctggttac caataaccct attcataaga
     3841 aggaacagac accagtctat tatttaaaaa acgacttgga tatggaagat ttggcaggga
     3901 ttcgtcagtt attattcact taaaaggctt ggttaatcca ggtctttttt gtgaaattca
     3961 cacaatctcc tcacattttt ttaaaaatta aaaaaagttg ataaacaaga aagcgcttta
     4021 ttttgtatac tagtaagtgt aaagaggaaa cacctcaaga tctttatcag gaggacagta
     4081 catgtcacaa gaaaaataca tcatggccat tgaccaggga actacgagtt ctcgtgccat
     4141 cattttcaac aaaaaagggg aaaaggttag ctcgagtcaa aaagagttta cccagatttt
     4201 ccctcaagca ggttgggttg agcacaatgc caatgaaatt tggaactctg ttcagtcagt
     4261 tattgcgggt gctttcatcg aaagtggtat caagccaaat caaatcgagg caatcgggat
     4321 taccaaccaa cgtgaaacaa cggttgtttg ggataagaaa acaggacttc ctatctacaa
     4381 tgctatcgtt tggcagtcac gccagacagc acctttggct gaacaactaa aaagccaagg
     4441 ttatgtggaa aaattccatg aaaagactgg tttgatcatc gatgcttact tctcagctac
     4501 caaagttcgt tggattttgg atcatgtaga gggcgctcaa gagagagcag aaaagggtga
     4561 attgctcttt ggtaccatcg atacttggtt ggtttggaaa ttgactgacg gtgcgactca
     4621 cgtgactgac tactcaaatg cagctcgtac catgctttat aacattaaag aactcaaatg
     4681 ggatgatgag attttggaaa ttctcaacat tccgaaggct atgctgccag aagttcgttc
     4741 taactctgaa atctacggta agacagctcc attccatttc tatggtggtg aggtgccaat
     4801 ctcaggtatg gctggggacc aacaagcagc cctctttgga cagttggctt ttgaacctgg
     4861 tatggttaaa aatacttatg gaacaggttc ttttatcatc atgaatactg gggaagaaat
     4921 gcagttgtct gaaaacaacc tcttgacaac gattggttac ggaatcaacg gcaaggttta
     4981 ctatgccttg gaaggttcaa tattcatcgc aggaagtgct attcagtggc ttcgtgacgg
     5041 tcttcgcatg gttgaaaatt caccagaatc tgaaaaatac gctcgtgatt ctcacaacaa
     5101 cgatgaagtt tatgtcgttc cagcctttac aggtctaggc gctccatact ggaaccaaaa
     5161 tgctcgtggt tccgtctttg gtttgactcg tggaacaagc aaagaagact ttatcaaggc
     5221 gactttgcaa tctattgctt atcaagtgcg tgatatcatc gacaccatgc aagtggatac
     5281 tcagaccgcc attcaagtac tgaaggtgga tggtggtgca gccatgaaca acttcctcat
     5341 gcagttccag gcggatattt taggcattga cattgcacgt gctaaaaacc tggaaacaac
     5401 agctctagga gcggccttcc tagcaggttt gtcagtaggg tactggaaag acttggacga
     5461 gttgaaactc ttgaacgaga caggagaact ctttgagcca tctatgaatg aatctcgcaa
     5521 ggaacaactc tacaagggct ggaagaaggc tgtgaaagca actcaagtct ttgcggaagt
     5581 agacgactaa tactggcaga ataaagcgat ttatttagaa agtgtgtaaa tatggaattt
     5641 tcaaagaaaa cacgtgaatt gtcaattaaa aaaatgcagg aacgcaccct ggacctcttg
     5701 attatcggtg gaggaatcac aggagctggt gtagccttgc aggcggcagc tagcggtctt
     5761 gagactggtt tgattgaaat gcaagacttt gcagaaggaa catctagtcg ttcaacaaaa
     5821 ttggttcacg gaggacttcg ttacctcaaa caatttgacg tagaagtggt ctcagatacg
     5881 gtttctgaac gtgcagtggt tcaacaaatc gctccacaca ttccaaaacc agacccaatg
     5941 ctcttaccag tttacgatga agatggagcg acctttagcc tcttccgtct caaagtagcc
     6001 atggacttgt acgacctctt ggcaggtgtt agcaacacac caactgcgaa caaggttttg
     6061 agcaaggatc aagtcttgga acgccagcca aacttgaaga aggaaggctt ggtaggaggt
     6121 ggagtgtatc ttgacttccg taacaacgat gcgcgtctcg tgattgaaaa catcaaacgt
     6181 gccaaccaag acggtgccct cattgccaac cacgtgaagg cagaaggctt cctctttgac
     6241 gaaagtggca agattacagg tgttgtagct cgtgatctct tgacagacca agtatttgaa
     6301 atcaaggccc gtctggttat taatacaaca ggtccttgga gtgataaagt acgtaatttg
     6361 tctaataagg gaacgcaatt ctcacaaatg cgcccaacta agggagttca cttggtagtg
     6421 gattcaggca aaatcaaggt ttcacagcca gtttactttg acacaggttt gggtgacggt
     6481 cgtatggtct ttgttctccc acgtgaaaac aagacttact ttggtacaac tgatacagac
     6541 tacacaggtg atttggagca tccaaaagta actcaagaag atgtagatta tctacttggc
     6601 attgtcaaca accgctttcc agaatccaac atcaccattg atgatatcga aagcagctgg
     6661 gcaggtcttc gtccattgat tgcagggaac agtgcctctg actataatgg tggaaataac
     6721 ggtaccatca gtgatgaaag ctttgacaac ttgattgcga ctgttgaatc ttatctctcc
     6781 aaagaaaaaa cacgtgaaga tgttgagtct gctgtcagca agcttgaaag tagcacatct
     6841 gagaaatatt tggatccatc tgcagtttct cgtgggtcta gcttggaccg tgatgacaat
     6901 ggtcttttga ctcttgctgg cggtaaaatc acagactacc gtaagatggc tgaaggagct
     6961 atggagcgcg tggttgacat cctcaaagca gaatttgacc gtagctttaa attgatcaat
     7021 tctaaaactt accctgtttc aggtggagaa ttgaacccag caaatgtgga ttcagaaatc
     7081 gaagcctttg cgcaacttgg agtatcacgt ggtttggata gcaaggaagc tcactatctg
     7141 gcaaatcttt acggttcaaa tgcaccgaaa gtctttgcac ttgctcacag cttggaacaa
     7201 gcgccaggac tcagcttggc agatactttg tcccttcact atgcaatgcg caacgagttg
     7261 gctcttagcc cagttgactt ccttcttcgt cgtaccaacc atatgctctt tatgcgtgat
     7321 agcttggata gcatcgttga gccagttttg gatgaaatgg gacgattcta tgactggaca
     7381 gaagaagaaa aagcaactta ccgtgctgat gtcgaagcag ctctcgctaa caacgattta
     7441 gcagaattaa aaaattaaga aaaaataaaa gaggtggagg gcagcattcc ttgtcgctcg
     7501 tcccttcttt ttaatggaga cagaaagatg atgaatgaat tatttggaga atttctaggg
     7561 actttaatcc tgattcttct aggaaatggt gttgttgcag gtgtggttct tcctaaaacc
     7621 aagagcaata gctcaggttg gattgtgatt actatgggtt gggggattgc agttgcggtt
     7681 gcagtctttg tatctggcaa gctcagtcca gctcatttaa acccagctgt gaccatcggt
     7741 gtggccttaa aaggtggttt gccttgggct tccgttttgc cttatatctt agcccagttc
     7801 gcaggggcca tgctgggtca gattttggtt tggttgcaat tcaaacctca ctatgaggca
     7861 gaagaaaatg caggcaatat cctggcaacc ttcagtactg gaccagccat caaggatact
     7921 gtatcaaact tgattagcga aatccttgga acctttgttt tggtgttgac aatctttgct
     7981 ttgggtcttt acgattttca ggcaggtatc ggaacctttg cagtgggaac tttgattgtc
     8041 ggtatcggtc tatcactagg tgggacaaca ggttatgcct tgaacccagc tcgtgacctt
     8101 ggacctcgta tcatgcacag catcttgcca attccaaaca agggagacgg agactggtct
     8161 tacgcttgga ttcctgttgt aggccctgtt atcggagcag ccttggcagt gcttgtattc
     8221 tcacttttct agtttatact cttcgaaaat caaattcaaa ccacgtcagc gtcgccttac
     8281 cgtactcaag tacagcttgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
     8341 tagaaaacaa ttatgttgat agagcttggg caagagccca atttcagcaa aaaatgaagt
     8401 aaatcttctc ataataaaac gcatcatatc aagcacgaaa attccacgag gtcaactaca
     8461 gtcagaaagc tgaacaacaa gccaaaacgc ccaaaaaagg cggcaaaaag caagcacctg
     8521 caagcaatgt gccgaaatgg tcaaatcctg attatgtcaa cgaattagac ccaaaaatcg
     8581 ttgatatgct agtagaattt cacaagtcac aaggcacttt ggaaactccc gaggcgcaag
     8641 cagaaatcgc ccaaaaacgt gaagaaatcg agcaaaggag agctgagctt gaggataaaa
     8701 aacaagagct tttgaaccgc ttgaacaaat agagtttcgc aagtattatg cttacaaatt
     8761 acttgagcaa ttaactaaaa tataaaccct gcctttatat ctaggcaggg tttatatttt
     8821 agaaattcac gtaggttgtt acggttttta catacccagt atagtttgag tttctatagt
     8881 attcagtgat aaacttccat tttctttgag caacatggat ataagtactt gttatgtagt
     8941 atggatatgg gctttgtgaa tccaagtaag actgataagc ttgtatacca aaatatgctc
     9001 caccaattat tgcaccccat ggacccccca ataaagcacc tatcctacca atcatataac
     9061 tgattccagc accagtcatg aagttagcga atgtgttagc ttgtttattc ccatgtattg
     9121 tgttgaagta atttcaaaca ttaggatcgt atgatctaaa agatatattt aggtcgattt
     9181 cattcttttg ataagccata taaaatgccc cattgatata gacgccgtca gcacgtcgtt
     9241 caatagtgtc tacacttcca tctggattga caacctcaag aacttcatcg cttaaaatat
     9301 ttacttgcgt atctccgaac cgcactgatg agtcattctc aaactgagcc tcaccagata
     9361 caactttaga gtttgccgat aagctatcat cagcaaaaac aacaagcgac ggggaaatgc
     9421 tagacataca gaaaacagac ataactagca aacacatgca tttaaacatc ttagacataa
     9481 cggaaactcc tttgtatttt tgattttttt caacttttat tatacaataa aaccaaataa
     9541 aaagaaagcg gtaacaatat gcttaatgcg aaaatttttt atatattttt atgtttgatc
     9601 gttatcgaaa ctacaggctt gttgttgttg aaaagaggtc tcgaaatggg ttatttagac
     9661 acagaagcta ttatcctcgc agttttttca tttgcttttt acaacctatg ttcattcgct
     9721 tgggtctgct ctacaataaa aaacaataaa aaataaatag acgtattttc aaaaaaaaaa
     9781 atgcatattt atcttagtaa aacgacgatt taaatcgtcg tttttttgta gtacgacggg
     9841 catgtcgtat atctgaggtg caagtcctcc gtgggcactt gctaccggtg aacccaaaag
     9901 cgattcccaa gcctgactat cgtgaggtag cggggagagg aagagatagc gaaatcgtgg
     9961 ctctacgaac aggaacgtga tagcaaggcg tatatagcgg ataaggaggc ttcaaactct
    10021 aaagtccaaa aaggtagtcg taacctatat gtgtaaatca cgagagtaat tgaattcgga
    10081 ctaaggtttg tgtgaaaaag ataaatcttt ctagagtcta aagactctgc gtcagatttc
    10141 ctattttcac tgtaaccttt taacgtcctc atatcttgta taaacgagga aagatgtacg
    10201 acttatcccg tgaggtttca tgagcgctga aagcgtagta acaacgaatc atgagaagtc
    10261 agccgagccc atagtagtga ggaaacttcc gtaatggaag tggagcgaag gggtgaatac
    10321 tcaaacagtc tggggagaga ctgtttgagg tctgtcgcta gaaagagaaa acgacagatc
    10381 gaagtaatcc tacttcactt gtgtctgtaa aatgagtggc ctgatagaac tggactttga
    10441 cacgtaatga ctagatgaag gttcaccaat ataagatgtc cctcaggcac caaaacaaga
    10501 aaggaatacg cacatgtcaa aattgctaga taagatatta tcacgcgaaa atatgctgga
    10561 agcctacaat caagtaaaat ccaataaagg ctcagctggg attgatggaa tgactatcga
    10621 agagatggat aattatctca gacaaaactg gcgcttgact aaggaactga taaaacagag
    10681 aaaatataag cctcaaccag ttcttagagt tgagattcct aaaccagacg gaggcatccg
    10741 tcaactagga attccaacag ttatggatag aatgattcaa caggccattg tccaagttat
    10801 tagccccatt tgtgaacccc atttctcaga tacgagttat ggcttcagac caaataggtc
    10861 atgtgaaaaa gccatcatga agttcttaga gtacttaaat gacggctatg agtggatagt
    10921 ggatatagac ctagagaaat ttttcgatac ggttcctcaa gatagattga tgtccttggt
    10981 acataacatt atcgaagacg gagatacgga atccctgatt cgtaagtatc ttcattcagg
    11041 tgttatcatt aatggtcagc gtcataaaac gctagttggc acgccacagg gaggaaattt
    11101 atctcctctc ttatccaatg tcatgcttaa tgaattggac aaggaattag aaaagagggg
    11161 acttcgattt gtgcgctacg cagatgattg tgtgattacg gtcggaagcg aggcagccgc
    11221 taagcgtgtg atgtattcag ccagtcgttt tattgagaag cgactaggtt tgaaagtaaa
    11281 tatgaccaag gctaagatta ccagaccaag agagctgaaa tacttaggtt ttgggttctg
    11341 gaaatcatca gatggttgga aaagtcgtcc ccatcaagat agtgttcgga gatttaagct
    11401 taaattgaag aaactaacac agaggaaatg gagtatagac ttaacaagac gtattgagca
    11461 actgaatttg tctattcgag gatggataaa ctatttctcg ctgggaaata tgaagcgcat
    11521 agtcgctagc atagatgagc gcttgcgtac tcgcctacga gtgattatct ggaagcaatg
    11581 gaagaagaaa tcgagacgac tatggggatt gcttaagtta ggagttccta aatggatagc
    11641 agataaggta tctggctggg gcgaccatta tcaattagta tctcagaagt cggtacttaa
    11701 acgtgctata tcaaaaccag tccttgaaaa acgtggactg gtttcgtgtt tggattatta
    11761 ccttgaacga catgcgttaa aagttagttg aaccgccgta tgccgaacgg catgtacggt
    11821 ggtgtgagag gggctagaga ttatccccta ctcgattaac tcccctgaaa tttattttaa
    11881 ttatgcaaat ttcacgtatt tttgatgctg agacgacgat ctgggaactt ttcagatatt
    11941 tttttgacta tctaaaatct atcattagaa aagcttagag cgccaaagga tttgagcgtt
    12001 tttctgattt ttaagacttt ttcccagtct ctttttcgat tgaagatgta attattctac
    12061 taactaacta acttcttagt actagccaac aacgataatc ataattcctc ctaaaattag
    12121 gaataataaa ggcaatagtt tttgtttttt catgtaaaaa acctcacttt tgttttctgc
    12181 tattttatgc taaaatatta aaaatcaaat ttaattccaa agtttgtaac taaaggggga
    12241 gcgctacatg tctaattcat ttgtcaagtt gttagtctct caattatttg caaatttagc
    12301 agatattttc tttagagtaa caatcattgc taacatatac attatttcaa aatcagtaat
    12361 tgccacatca ctagttccta tcttaatagg aatatcctct tttgttgcga gtcttttagt
    12421 tccgttggtt actaaaaggt tagcgctaaa tagggtttta tctttatctc aatttggaaa
    12481 gactatatta ttggcgatac tggtaggaat gtttaccgta atgcaatccg tagcgccttt
    12541 ggtgacctat ctatttgttg ttgcaatttc catactagat ggttttgcag cacccgtttc
    12601 ctatgctatt gtgccacgct atgcgaccga tttgggtaag gctaattcag ccttatcaat
    12661 gactggtgaa gctgttcaat tgataggttg gggattaggt ggactcttgt ttgcaacaat
    12721 tggtctgtta cctaccacgt ttatcatttt agtcttgtat atcatttcta gctttctgat
    12781 gttatttctt cctaacgctg aagtggaggt gttagagtca gaaactaatc ttgaaatttt
    12841 gctcaaaggt tggaagttag ttgctagaaa tcctagatta agactttttg tatcagcaaa
    12901 tttattggaa attttttcaa atacgatttg ggtttcttcc attatacttg tttttgtaac
    12961 ggagttatta aataaaacgg aaagttactg gggatattct aatacagcat actctattgg
    13021 tattataatt agtggcttaa ttgcttttag gctatctgaa aagttccttg ctgctaaatg
    13081 ggaaagtatt ctttttcctc ttgtagctat ggcaatagtg acactgacta ttctatattt
    13141 tccaaacgca cagatgtttt tattattttc agctttagtt ggtatgttat cgcaactaaa
    13201 agaagttcct gaaagtgtat ttcttcagga aacagtagag gaaaatcatt tagttaatgt
    13261 ctattccgtt cttgaagtga tttctacatt agcattttca gtatttgttt tgctaatgag
    13321 ctatattact gagagttttg gtattagcat cagtttttgg ctatcagcca tttgtctgat
    13381 gatagaagct attttaattt atatcagacg agattatttt aaatgagaga gtggttaaaa
    13441 agtctttaaa aatcagaaaa gcgcatagta tcaggtgttg aaaaaacttg atattgtgtg
    13501 ttttattatg ggaagattta cttcattgtc tcctgaaatg gagttttgaa gcaggatcac
    13561 tctatttgaa aatatacata gaaaaaccgc ataatcctta aaataagctg aaatctattg
    13621 gaaacatacg gtaaacaatt gaaaagatac tatataaagt ggtacaatgg tagaaaaata
    13681 agctagtaag aatcactctt attttagcga aaaattacag aaatgaatgg tttttcttga
    13741 tgaaacagag aaaagaattg tacctctttc ttggtcggac agccttgtat tttcttatct
    13801 ttctagggct gctttacttc tttagctatc ttggtcaggg tcaaggaagc tttatctata
    13861 atgaatttta acttgaagga gaatccctat tgtgtcaaat aaaccaatag cagatatgat
    13921 tgaaaccatt gagcattttg ctcagacaca gcctagctat cctgtctata atgttttggg
    13981 gcaggaacac acttatggcg atttaaaggc tgattcggat agtttggctg cagtcattga
    14041 ccaactaggc ttgcctgaaa agtctcctgt ggttgttttt ggtggccaag aatatgaaat
    14101 gttggcaacc tttgtagcgc tgactaagtc aggtcatgcc tacattccaa ttgatagcca
    14161 ttcggccttg gagcgagttt cagctatttt agaagtagca gagccaagct tgattattgc
    14221 catttcagcc tttcccttgg agcaggtttc tacaccaatg ataaatctag ctcaggttca
    14281 agaagccttt gcccaaggga acaactatga aatcacgcat ccagtcaagg gagatgataa
    14341 ttactacatt atctttactt ctggtacgac tggtaagcct aagggagtgc agatttcaca
    14401 tgataatctc ctcagcttta caaactggat gattacggat aaggaatttg cgacaccgag
    14461 tcgtccgcaa atgctggcac agccacctta ttcttttgac ttgtctgtca tgtattgggc
    14521 accgaccttg gcacttggtg gtacgctttt cactcttcct tcagtcatca ctcaggactt
    14581 taagcaactc tttgcggcta tcttttcatt gccaatcgct atctggacat caacaccatc
    14641 ctttgcagat atggccatgt tgtctgaata cttcaacagt gaaaaaatgc ctggaatcac
    14701 gcatttctac tttgatggtg aagaattgac ggtcaaaaca gctcaaaaac tgcgcgagcg
    14761 tttcccaaat gcccgtatca tcaatgctta cggcccaaca gaagcgacag tagctctgtc
    14821 agcagttgcc gtgacagacg agatgttagc gactctcaaa cgcctaccaa tcggctatac
    14881 caaggctgat tctccaacct ttatcattga cgaggaagga aataaactgc caaatggcga
    14941 acagggagaa atcattgttt ctgggccagc tgtttcaaaa ggttatatga acaatcctga
    15001 aaaaacagca gaagccttct ttgagtttga aggtctgcca gcctatcaca caggcgatgt
    15061 gggaaccatg acagatgagg gcttgcttct ctacggcgga cgcatggact tccagattaa
    15121 gttcaacggt taccgcattg agttagaaga tgtctctcaa aacctcaaca agtctcgctt
    15181 tatcgaatct gctgtcgcag taccgcgcta taacaaggac cacaaggtac aaaatctatt
    15241 ggcttatgtc atcttaaaag acagtgttcg tgagcagttt gagcgagata tcgatattac
    15301 caaggccatc aaggaagacc tgacagacat catgatgtcc tacatgatgc catctaaatt
    15361 cctttaccga gacagtttgc cactgactcc aaatggaaag attgacatca aaggattgat
    15421 taacgaggtg aataagagat gatggagttt tttcaacagc ttcctcattt agagccatat
    15481 ggcaatcctc agtattttgt ttatgtgatt gctgcaacct tgcccatctt tataggcctc
    15541 tttttcaaga aacgctttgc ctggtatgaa gtgttggtaa gtctcttctt tattgtcacc
    15601 atgttggtgg gtggaaagac caatcaacta gctgccttgg gtatttacct ttgctgggaa
    15661 atattgctcc tgcttttcta caagcattat cgaaaaagca aggatggcaa gtgggtcttc
    15721 tacttagtta gttttctgtc cctacttccg attatctttg tcaaggtgca accagctatc
    15781 aatggaacgc agtctttgct tgggttcttg ggaatttctt acctgacctt tcgttcggtt
    15841 gggattatca tcgagctgag agatggagtg attaaggatt ttaccctctg ggaattcctc
    15901 cgtttccttc tcttcatgcc aactttctcg agtggtccaa tcgatcgctt taagcgattt
    15961 aatgaaaatt atcaggctat tcctgagcga gatgagttga tggatatgct ggatgaatct
    16021 gtccgctata tcatgtgggg ctttttgtat aagtttatcc tagctcatgt tttaggagag
    16081 accttactac ctcctctgaa gaatttagcc ttgcagtcag gtggcttctt taatctctat
    16141 gccttggcag ttatgtatac ttttggtctg gagctcttct ttgactttgc aggttattct
    16201 atgtttgctt tggccatctc aaacttgatg ggaatccgta gccctatcaa ctttaacaag
    16261 ccctttttat caagggattt aaaggagttt tggaatcgct ggcatatgag tctgtccttc
    16321 tggttccgtg actttgtctt tatgcgaatg gtgatggtgt taaccagaaa gaaagtcttt
    16381 aaaaatcgta atgtaacctc aagcatggcc tacattgtaa atatgctgat tatgggattt
    16441 tggcatggtg tgacctggta ctatatcgcc tatggactct ttcatggact aggcttggtc
    16501 atcaatgatg cctgggttcg caagaaaaaa acgctcaata aggaacggaa aaaagcaggg
    16561 aaggctgccc tacctgagaa tcgctggatt cagttgcttg gcatggttgt cactttccat
    16621 gttgtcatgt tgtcattctt aatcttttct ggattcttga ataatctatg gtttaaaaaa
    16681 taaaaggaaa taaaatatgg atatcaaatc agaagttatt gaaattattg atgagttgtt
    16741 tatggaagat gtttctgaca tgatggatga agatcttttt gatgcaggtg tcttggatag
    16801 tatgggaacg gttgagttga ttgtggagat tgagaaccgt tttgacattc gtgtccctgt
    16861 aacagagttt ggtcgtgacg actggaatac agctaataaa atcatagctg gtattgtgga
    16921 gctacaaaat gcttaaacgc ttatggatga tcttcggacc ggtcttgatc gctggtttgt
    16981 tggtttttct gctcattttc ttttatccta ctgagatgca tcataatcta ggagctgaaa
    17041 agcgttcagc agtggctact actatcgata gttttaagga gcgaagtcaa aaagtcagag
    17101 cactatctga tccaaatgtg cgttttgttc ccttctttgg ctctagtgaa tggcttcgtt
    17161 ttgacggtgc tcatcctgcg gtattagctg agaaatacaa tcgttcctac cgtccttatc
    17221 ttttaggaca ggggggagct gcatcgctta accaatattt tggaatgcaa cagatgttac
    17281 cacagctgga gaataaacaa gttgtgtatg ttatctcacc tcagtggttc agtaaaaatg
    17341 gctatgatcc agcagccttc cagcagtatt ttaatggaga ccagttgact agttttctga
    17401 aacatcaatc tggggatcag gctagtcaat atgcagcgac tcgcttactg caacagttcc
    17461 caaacgtagc tatgaaggac ctggttcaga agttggcaag taaaggagaa ttgtcgacag
    17521 cagacaatga aatgattgaa ttattggctc gttttaatga acgccaagcc tccttttttg
    17581 gtcagttttc ggttagaggc tatgttaact acgataagca tgtagctaag tatttaaaaa
    17641 tcttgccaga ccagttttct tatcaagcaa tagaagatgt tgtcaaagca gatgctgaaa
    17701 aaaatacttc caataatgag atgggaatgg aaaattattt ctataatgag cagatcaaga
    17761 aggatttgaa gaaattaaag gattctcaga aaagctttac ctatctcaag tcgccagagt
    17821 ataatgactt gcagttggtt ttaacacagt tttctaaatc taaggtaaac ccgattttta
    17881 tcattccacc tgttaataaa aaatggatgg actatgctgg tctacgagag gatatgtacc
    17941 aacaaacggt gcagaagatt cgctaccagt tagaaagtca aggttttacc aatatagcag
    18001 atttttctaa ggacggcggg gagcctttct ttatgaagga caccattcac cttggttggt
    18061 tgggttggtt ggcttttgac aaggcagttg atcctttcct atccaatccc acaccagctc
    18121 cgacttacca tctgaatgag cgctttttca gcaaagattg ggcgacttat gatggagatg
    18181 tcaaagaatt tcaatagata atataatata gaagagttca agaatgaaac tagttttcac
    18241 gttttttctt gactcttttt ttgcttgtga tataattaac tggtaaacaa aatgtcaaag
    18301 aatagtattt ttctcttaaa aaagagaagt ctaaaaggaa aggagtcaga tatgagacag
    18361 ctagcaaagg atatcaatgc ttttttgaat gaggtgattt tgcaggcgga aaatcagcat
    18421 gaaatcctaa taggtcattg cactagcgag gtggccctga ccaatactca ggagcatatc
    18481 cttatgctct tgtcagagga atctttaaca aattcagaat tggcccgtcg tctcaatgtc
    18541 agtcaggcgg cagttaccaa ggccattaag tctttggtca aggaagggat gttggaaaca
    18601 tctaaagatt ctaaagatgc gcgtgtgatt ttttatcagt tgactgactt ggctcgtcca
    18661 atcgctgagg agcaccacca tcaccatgag catacacttt taacctatga acaagtggcg
    18721 actcagttta ctccaaatga acaaaaagtg attcagcggt ttttgactgc tttagtagga
    18781 gaaatcaaat aatgagatat attacggtag aggatttgtc cttctattat gataaggagc
    18841 ctgttcttga acatatcaat tatagtgttg atagtgggga atttgttacc ttgactgggg
    18901 aaaatggagc ggctaagacg acgctcatca aggctagtct tggaattctg caaccacgca
    18961 ttggaaaggt ggctatttca aagacaaata cgcaaggtaa gaaattgaga atagcctatc
    19021 ttcctcaaca aattgccagt tttaatgctg gttttccaag tacggtctat gaatttgtca
    19081 agtcgggtcg ctatccgaga aaaggctggt tccgtcgttt gaatgctcat gatgaggagc
    19141 atatcaaggc cagtctggac tcagttggca tgtgggaaca tcgagacaaa cgcttggggt
    19201 ctctatctgg gggacaaaag cagcgagcgg tgattgcgcg tatgtttgct tctgaccctg
    19261 atgtgtttat cctagacgag ccgacaacgg ggatggatgc aggaagtaaa aatgaatttt
    19321 acgaactcat gcaccacagc gcccatcatc atggcaaggc tgttttgatg attacccatg
    19381 accctgaaga agttaaggat tatgcggatc gcaatattca tctagtccgt aaccaagact
    19441 cgccatggcg ttgtttcaac gttcatgaga atgggcagga ggtgggccat gcttagttta
    19501 ttatcttatg actttataca acgcgccttt ttggcggtta ttgctatgag tcttttctca
    19561 ccggtattgg gaaccttcct catcttgcgt cgtcagagtt tgatgagtga tacccttagc
    19621 cacgtctcac tttcaggtgt agcctttggt ctggttttgg ggatttctcc aactgtttct
    19681 actattgcca ttgtcttgat tgcggcggtc tttctggagt atctccgtac ggtttacaag
    19741 agctttatgg aaatcgggac agctatcctc atgtcaacag gtttggctgt ttctctgatt
    19801 gtcatgagca agggtaaaag ctcgagttca atgagtttgg accaatatct ctttggttcg
    19861 atcgtgacta tcagtgaaga acaggtcatt tccctctttg tcattgcggc ggttgttttg
    19921 attttgacct ttctctttct tcgtcctatg tatatcttaa cttttgacga agatacggcc
    19981 tttgtggatg gcttgccagt tcgtaccatg tccattcttt ttaacatggt gacaggggtg
    20041 gctattgccc ttatgattcc tgcagcagga gctcttctgg tatcgaccat tatggtcttg
    20101 ccagctagta ttgccctgcg tctggggaaa aactttaaat cggttatgct gcttgccagt
    20161 gcgattggct ttttgggaat ggtagcagga ctttacattt cctactatgc agaaacacct
    20221 gcaagtgcaa gtattaccat tatttttgta actgtcttta tactaatcag tttagtaaga
    20281 cgttttatca aataggagac gaacgtgaaa aaaattagct tattactagc cagtctatgt
    20341 gccttgtttt tagtggcttg ttccaatcaa aaacaggcag atggtaaact caatatcgtg
    20401 acaacctttt accctgtcta tgaatttacc aagcaagtcg caggagatac ggctaatgta
    20461 gaactcctaa tcggtgctgg gacagaacct catgaatacg aaccatctgc caaggcagtt
    20521 gccaaaatcc aagatgcaga taccttcgtt tatgaaaatg aaaacatgga aacatgggta
    20581 cctaaattgc tagatacctt ggataagaaa aaagtgaaaa ccatcaaggc gacaggcgat
    20641 atgttgctct tgccaggtgg cgaggaagaa gagggagacc atgaccatgg agaagaaggt
    20701 catcaccatg agtttgaccc ccatgtttgg ttatcaccag ttcgtgccat taaactagta
    20761 gagcacatcc gcgacagctt gtcagcagat tatcctgata aaaaagagac ctttgagaag
    20821 aatgcagctg cctatatcga aaaattgcaa gccttggata aggcttacgc agaaggcttg
    20881 tctcaagcaa aacaaaagag ctttgtgact caacacgcag cctttaacta tcttgccttg
    20941 gactatggac tcaaacaagt cgcaatctca ggactttctc cagatgcaga gccatcagct
    21001 gctcgcttgg cagaattgac agagtatgtc aagaaaaata aaatcgccta tatctatttt
    21061 gaagaaaatg cctcacaagc ccttgctaac acactttcaa aagaagcagg tgtcaaaact
    21121 gatgtcctca atcctttaga aagtctgaca gaagaggaca ccaaggctgg agaaaattac
    21181 atctctatca tggagaaaaa cctcaaggct ttgaaacaaa caacagacca agaaggccca
    21241 gcgatcgagc ctgaaaaggc agaggatacc aagacagtcc aaaatggtta cttcgaggat
    21301 gcagctgtca aggaccgcac cttgagtgac tatgcaggta actggcaatc agtttatcct
    21361 ttccttgaag acggcacgtt tgaccaagtc tttgactaca aggctaagtt gactggtaag
    21421 atgacccagg ctgagtacaa ggcttactat acaaaaggct atcatacaga tgtgactaag
    21481 attaacatta ctgataatac tatggaattt gttcaaggtg gacaaagcaa gaaatacact
    21541 tacaagtatg tcggtaagaa aattttgact tacaagaaag gcaatcgtgg cgtgcgtttc
    21601 ctctttgaag ccacagatgc tgacgctgga caattcaagt atgttcagtt tagtgaccac
    21661 aatgttgccc cagttaaggc agaacatttc catatcttct ttggaggcac aagccaagaa
    21721 gccctctttg aagaaatgga caactggcca acctactacc cagataacct atctggccaa
    21781 gaaatcgccc aagaaatgtt ggcgcattga tgagaaatcg actagttcat aagagctagt
    21841 cggttttttg atactagatg gctaacttca ttatagacct ttcagaactt taaacaataa
    21901 ataaaactct tgaaatatct gggcttatat gctagaatgt agttagtgta taaggttcat
    21961 tagaacacca aagcccctaa ctagtgccat agttaagggc ttttttgacg tatcttagcg
    22021 atttaacggg tgtttatagg ctagtcattc ggtctacttc ttaccatcta gccatttgca
    22081 gacgaaatac aagataattc cagctataac atctgctata atagtaagag caagctctgg
    22141 tataaggctc attagtttca cctcctctca cgaaccgtaa ggaacgtaat cggtaaccga
    22201 tgacaaaaat agtatatcac actacattca ggtcatcaac cttacttaat gcttgaacta
    22261 ttgtagatta tatgctagaa tgtagttaat tgataaggtt cattagaaca ccaaagcccc
    22321 taactatggc cgtagttaag ggcttttttg acgtatctta gcgatttaac gggtgtttat
    22381 aggctagtca ttcggtctac tccttactat ctagccatct gcagacgaaa tacaagataa
    22441 ttccagctat aacatccgct ataatagtaa gagcgagctc tatgataagg ctcattagtt
    22501 tcacctcctc tcacgaaccc ataggaacgt aatcggtaac cgatgacaaa aatagtatac
    22561 cacaatacat ttagatcatc aaggtcactt aattcttgaa atatcagatc taagagaaaa
    22621 atctttaaaa tcagaaaaac gcataatatc aggtgtgcaa aaacttgata ctatgcgttt
    22681 tattgtggga aggtttactc cattttctcc tgaaattgag tttttgtcca gcctctgttt
    22741 ttagggttgc taagaaaata atgtcatgtg gtgaatattt gtaaatcagt cagcagacag
    22801 aacgatactc ttcgaaaatc tcttcacatc atgtcagctt cgtctttccg tatatatgtg
    22861 actgacttca tcagttctat ctacaacctc aaaacagtgt ttcgagctga cttgatcaat
    22921 tttcaaatct gtactttgag caagctgaga ctagcttcct atttgatttt cattgaatat
    22981 cagaaaccca ttctccatca aataattcga ctgcgtctaa taatttttga tctggcacgg
    23041 tgtctgaaat aaaggttgtg tatttggaga ggggattaat tttaaaaaat ccagtcttgt
    23101 aaaatttaga actatcaatc agtaagatgg tttcatgggc tttgtcaata atattctttt
    23161 ttgaaatagc ttggctgaga gaagcttcat aaacatattg gtcatcaata cctcttgctg
    23221 aacaaaatgc taaatcgata ttaaaatgat ctaataaaga attttcctta tcatagttga
    23281 ccacggaaca ggattgatgt ttgacctcgc cagatgtgat aaagattttg gagctatctt
    23341 taacagtttc agatagggtt tgtgcagtat gtaaaccatt tgtaaaaata atcaaattat
    23401 caagttcaga aagataggga cagagttcgt agacagtagt actagaatct agatagatac
    23461 acataccaga ccgaataaag tctttagcga gactagcgat tagtcttttt tgcctagtac
    23521 tttctccttc acgtatttga tgagaaagtt caattgtgtt catagaggac agggtcacgt
    23581 atccgtgctt tcttttgata agaccttgat tttctaagaa aattaaatca cgacgtaagg
    23641 tacttgtgct ggagaaagtg atttctgcca gctcttttac ggcaattctt tttttctttt
    23701 tgataatttc aatcaattca agtacacgtt catcttttat cataagctcc tcctaattta
    23761 tcatttcaac tatattatag cacaaattgg aggaatttga attattttta tgaatattgg
    23821 gttaacattt gaacattatt caagtaagcg ttcacatatt gaaaaaataa aacgtgggga
    23881 ttataataaa gttaatcaag gacgaagaga gaagaaaaat ggaagcggtt ttagcaatag
    23941 atttaggtgc gacttctgga agagcaatcg ttggttacct ttctgaaaat aaactagtaa
    24001 tggaagaaat aaatcgcttt tctaatctac ctattagagt aaaagggcat ttatcttggg
    24061 atattgactt tctactagct aaaattcttg aaagtatccg cttggctaat actagttaca
    24121 agattttatc tatcggtatt gacacatggg gagttgattt tggactgatt gataatgaag
    24181 gtaagctgtt attacaacct gttcattatc gtgatgaaag aacaaaggga gtgttaaagg
    24241 aaatatctga aatgactgaa ttagaaaaac tgtattcaga gacaggaaat cagattatgg
    24301 agataaatac cttgtttcaa ctctttaagg cacgtcaaga atctcctgac tctttctata
    24361 agaccaataa gattctttta atgccagatt tgtttaatta tctcttgaca ggtaagtttg
    24421 ctacagaaaa aagcattgct tcaacaactc aattatttga tcctaggagt caaaattgga
    24481 atcagaatat cttaaaacta tttgaattgg attcatcttt acttcctgaa attgtttcag
    24541 agggaaatgt tcttggaagg ataaaagagg agtatggttt aggcgatatt cctgttgtga
    24601 atgtttgtag tcatgataca gcaagcgcga ttgtctcagt acctaagaca gaaggtagtt
    24661 tatttatttc atcaggtact tggtctttgg ttggagtgga acttacttca ccgattctta
    24721 ctaccgaatc cttcagttat ggatttacaa atgaagtcgg taaagatgga gtgattacat
    24781 ttctgaagaa ttgtacaggg ttgtggatca tagaggaact aagacgttca tttgaacgaa
    24841 gagggaaagc ctattctttt gatgatatta ggacaatggt ggagaaagaa aaagaaaatc
    24901 ttcctctgat tgatactgaa tcaactgaat ttgcaacaga atctgatatg cacaagactt
    24961 tgacagaata tctagcttat catcatgaaa ctagagagtg gacagatgga caactattta
    25021 agattgttta tgaaagccta gctgaaacgt ataggaaagc gatagagtta ctagaagaac
    25081 taactcataa ggtttataag aggatatatg tgattggagg aggtgctaga gccagttact
    25141 ttaaccaaat gattgctgat agaactggta aagaggttct tacaggtttg actgaggcta
    25201 cagctgtggg gaatattgtt gtgcagctca tagctatggg acaattaaaa gggatggaag
    25261 aggctcacca tgttattgag gagtttctac aattagagag ttattactcc caaaagaatt
    25321 aaaaagattg agagtttgta aatttgcctc cctccccctt cttagctttt gtgcaggaag
    25381 gggggataat tggtgaattg aaaaatattt agtgttttga tatgaggagg acaaggatgt
    25441 cagatgtaaa acaagaatta attaaatatg gtaagaagct agtagaaaca gatttgacga
    25501 aaggaacagg tgggaatctc agcgttttcg atcgtgaaaa acaattgatg gcaattaccc
    25561 cgtcgggtat tgatttcttt gaaatcaaag aatccgatat tgtagtgatg gatattaatg
    25621 gaaatgttgt agagggagaa cgcttgccat ctagcgaatg gtatatgcat ttgattcaat
    25681 atcaaactcg tgatgatatc gatgcaatta tccatgctca tacaacttat gcaacagtat
    25741 tagcttgtct cagagaacca cttccagcga gtcattatat gattgcagtg gcagggaaag
    25801 atgttcgggt agctgagtat gcaacatatg gcacgaaaga attggctgtg aatgcagcta
    25861 aagcaatgga aggtcgtaga gcagttttac tagcgaatca tggaatttta gcaggtgcac
    25921 aaaatttatt gaatgcattt aatattgttg aagaagttga atattgtgca aaaatttatt
    25981 gtttagctaa gaattttgga gagccagtag ttcttcctga tgaggagatg gaattgatgg
    26041 cagaaaaatt taaaacatac ggtcagagaa aatagggagg atattaatgt taaaacatat
    26101 accgaaaaat atttctccag atttattgaa gactttaatg gaaatgggac atggagatga
    26161 aatagtatta gctgacgcga attatccttc tgcctcatgt gcaaataagc taattcgttg
    26221 tgatggtgta aatattccag aattattaga ttccattctg tatttaatgc cattagatag
    26281 ttacgtcgat agttcaattc agtttatgaa cgttgtttcg ggtgatgata ttcctaagat
    26341 atggggtacc tatagacaga tgattgaagg tcatggtaca gatcttaaaa cgattactta
    26401 tcttagaaga gaagactttt atgaacgtag taagaaagct tatgctattg ttgctacagg
    26461 agaaacttca ctttatgcta atattatcct taagaaagga gtagttgttg aaagagaaaa
    26521 tgttcaatag aggaatttta gttgccagtc atggtaattt tgctagcgga gctctcatga
    26581 ccgcagaaat gtttgttggt gagacaacaa atgatagagt taggacatta ggtttgatgc
    26641 ctggagagaa tattgtagag tttgagcatt attttaaaaa tcaagtggat gaactgttag
    26701 actcaaatca agaggttatc gttttgactg acttgattgg aggaagtcct aataatgtgg
    26761 ctttgtcacg gtttttaaat ttggattcag ttgatattgt aacagggttt aatatccctc
    26821 tcctagtgga attaatatca agttatgatt caaaaatcaa tttagaagaa attgttcaca
    26881 atgctcaaaa tagtttgttt aatgttaaac aacaacttaa cgtagaggag gaagaagatt
    26941 tatgtctata gagtttgttc gtattgatga ccgtctggta catggtcaag ttgtcactac
    27001 gtggctaaaa aagtatgata ttgagcaagt tatcattgtt aatgatcgca tctcagaaga
    27061 taaaacacga caatctattt taaagatttc tgcaccggta ggtttaaaaa ttgttttctt
    27121 tagtgtaaaa cggtttgtgg aagttttaaa ctctgtgcca ataaaaaaga gaacaatgct
    27181 gatatataca aatccaaaag atgtgtatga ttctattgaa ggaaatttaa aattggagta
    27241 cctcaatgta ggacagatga gtaaaacgga ggaaaatgaa aaggtaacgg gaggtgtagc
    27301 tctaggtgaa gaagacaaat attattttaa gaaaatagtt gataagggaa cgagagttga
    27361 aattcaaatg gttcctaatg ataaagttac aatgttggaa aaatttttat aaaaataatt
    27421 taaggaggta cagtatatgc tattcacaca agcattactg gtgacattag ttgggattat
    27481 tgccactatt gactataatg gaccgttatt tatgattcac cgtccgttag ttacaagtgc
    27541 aatggttggc ttagtattag gagatttcac ccaaggtgtt cttattggtt cagctcttga
    27601 attaacttgg ctcggtgtaa caggtattgg aggttatact ccaccagata ctatttcagg
    27661 tgcgattatt ggtactgcat ttggtatttt atctggtcaa ggagaaactg ctggtatcgc
    27721 tatagcagtt ccaattgcag ttgctaccca acagttggat gttcttgcaa aaactttaga
    27781 tgtttatttt gtgaaaaaag ctgataatga tgctaaaaac ggagattatt caaagatcgg
    27841 tttttatcat tattcaagtt tggttttaat cacgttattt aaaattgtac caattttcct
    27901 agctattatg cttggagggg aatatgtggc agacttgttt gctaaggttc caccaatcgt
    27961 tatgcaggga cttaactctg caggtgcttt actaccttca attggttttg gtatgctttt
    28021 aaatatgatg ctcaagaaaa atatgtgggt attcttgttg attggattca tttgttctgt
    28081 gtatggagga atgtcaacca ttgggatctc actagttggt attgcggtag catacttcta
    28141 cgatatgatt ggaagcaaac cacaagaaac aacttcaagt agtgatgttg aggaggatct
    28201 tgatctatga tgaataataa agtaactaaa gttgaactta aaaaagtttt caaacgaagt
    28261 tttatgtatg gttcttcatg gaactatgag agaatgcaga acctaggttt tctatataca
    28321 attcttccag tattgaaaaa actataccca gacaaagatt cagcttctcc tgcaatgaaa
    28381 cgtcaccttg agtttttcaa tactcatcaa acagcggcac catttattct tggagttact
    28441 tccgctatgg aagaacaaga aggaaatgaa ggtgcagctt caattactgg tattaaagtt
    28501 ggcttgatgg ggccactggc tggtctagga gatagtttgt tctggctgac actagttcct
    28561 atctgtttta gtattggtgc gtcttattct aaagacggcg gtgctttagg tatctttatc
    28621 gccttaatat tgtttaatat tattaatatt cctgttaaat atttcggttt gaaatatggg
    28681 tatactaagg gttctagtct tatccaagaa aataatacaa aaggaacatt gaatcgcgtt
    28741 acgagtatgg cgacagcatt agggctagta ctagtgggtg gtttgattcc atcaatggtt
    28801 ggtattaatt ttggattaga atttaagcag ggggaacttg ttatttctgt tcaagaaatg
    28861 attacaaaat taattccagg atttatccct atggctttga ctttattaat gtgtaaatta
    28921 attagaaaag gaaagaatcc ggttgtacta atctttagtg ttatggctat tggagttatt
    28981 ctagttgttt taggaatttt gaagtagtag aaagtgtgga ggtggtattt gggatatcac
    29041 ctccattttg gaagagaggt aaagagtgaa attatggtat aagaaagctg ccgcaaattg
    29101 gaatgaagcc ttgccgattg ggaacggtca tttaggtggt atgatttatg gttcagctac
    29161 aaaagaatgt attcaactaa acgatgagac tatttggtat agaggaaagt cagatagaaa
    29221 taatccagac tcactattgc atcttaaaaa aattcgggaa tatcttttag atggagaaat
    29281 tcagaaagcc gaagaattga taaagttaac agtgtttgct accccaagag atcaaagcca
    29341 ctatgaatta cttggggaac tttacattga gcatatagat attcagtctt gtgctctttc
    29401 attgtatgaa agagagctag atttagatac agctatttct aatgttgtgt ttgagcctaa
    29461 tagttgtaat ttacaaataa aaagagaata ttttacgagt tttaataaga atattttatg
    29521 ttgccgtata gtgtcatcag ttcaaaacac attaaattta aacattaatt tgggtagaaa
    29581 taaacggttt aatgacgaag tatctaaact ggattcaagt acaattttaa tgtcggcctc
    29641 tgctggaggt agaaaaggtg ttcagtttaa agtagtatgt cattctaagg ttacggatgg
    29701 tgaagtaagt gtattgggag agacaatagt tattcggaat gctacagagg tatttcttta
    29761 tctcaaatca atgacggatt attggggaaa tatagatatt tcttctcttc agggagaatt
    29821 tagtagtatt gattacttta cagaaaaaga tgaacatgta aaaaaatatc aggagcaatt
    29881 taatagagtt gattttaaac tagactatag taaaggttgt cttagcattc caacgaatct
    29941 acttcttgaa aacactaaaa agtatagtaa ctacttgact aacttgttat ttcattatgg
    30001 aagatatctg ttaatatcgt ctagtcaacc gaatggttta cctgccaatc ttcaaggaat
    30061 atggtgtgat gaattaaatc caatttgggg ttctaaatat acgattaata ttaatactca
    30121 aatgaattat tggatggtag gtccatgtga tttaccagaa gtagaatatc cattatttga
    30181 tatgctcgaa agaatgagag aaccgggaag actaaccgct aagaaaatgt atggagctag
    30241 aggttttaca gcacatcata atacggatgg ttttggcgat acggctcccc aatctcatgc
    30301 catgggggct gcaatttggg tattaactat tccatggtta tgtactcata tttgggaaca
    30361 ctatttatat ttccaagatg agcgtattct tacggaacat tttgaaatga taaaagaagc
    30421 atttcttttc tttgaagatt atttatttga ggtggatggc tacttgatga caggtccaag
    30481 tgtctcaccg gaaaataaat atcgcttaaa aaatggtatt gaaggaaatg cttgtctatc
    30541 atctacaatt gataatcaaa ttttaagata tttttgtgat tcatgcattg gaattgcaaa
    30601 acaattagga gacaattcgg attttattag tcgtgtgaag gagttaaaaa agaaattacc
    30661 tagaacaaaa ataggtagta atgggcaaat acaagaatgg ctagaggatt atgaagaagt
    30721 agagcctggt catagacaca tttcacctct atttgggctt tatccttata atgagattga
    30781 tattcataaa actccggaat tagcagaagc agctaaaatc actatcaata ggagattatc
    30841 aaacgctaac tttttatctt cacaggatag ggagcaagcg attaataatt ggttagtaag
    30901 tggtttgcat gctagtacac aaacaggttg gagtgctgca tggctgattc atttttttgc
    30961 gagactatat caaggtgaac ctgcttataa ccagattaat ggtttgttaa ataatgcgac
    31021 tcttggcaat ttatttcttg accatccacc atttcaaatt gatggtaatt taggtttggt
    31081 gagtggaatt tgtgaattat tagtacagag ccatcataat tggttatcac taattccagc
    31141 tttaccttct gcttggtcag aaggagaagt gaaaggtttc agagtaagag gaggatataa
    31201 ggtatcgttt gcttggaaaa atggggatat aacattccta aaattggaag gaggaaacaa
    31261 agatcaaaaa gtaagagtaa gaatatatgg caaaaatact gatgtacaaa atattgaatt
    31321 ggtatttaat tcagaaaaaa ttattgagtt aaatttttag gtataagtca tgaataaaga
    31381 aaaaataaaa agaaaattaa tcacaatact gtttgtatgt attgggatgt tatgttttgg
    31441 attgttagca ggagttaagg ctgataatcg tgttcaaatg agaacgacga ttaataatga
    31501 atcgccattg ttgctttctc cgttgtatgg caatgataat ggtaacggat tatggtgggg
    31561 gaacacattg aagggagcat gggaagctat tcctgaagat gtaaagccat atgcagcgat
    31621 tgaacttcat cctgcaaaag tctgtaaacc aataagttgt attccacgag atacgaaaga
    31681 attgagagaa tggtatgtca agatgttgga ggaagctcaa agtctaaaca ttccagtttt
    31741 cttggttatt atgtcggctg gagagcgtaa tacagttcct ccagagtggt tagatgaaca
    31801 attccaaaag tatagtgtgt taaaaggtgt tttaaatatt gagaattatt ggatttacaa
    31861 taaccagtta gctccgcata gtgctaaata tttggaagtt tgtgccaaat atggagcgca
    31921 ttttatctgg catgatcatg aaaaatggtt ctgggaaact attatgaatg atccgacatt
    31981 ctttgaagcg agtcaaaaat atcataaaaa tttggtgttg gcaactaaaa atacgccaat
    32041 aagagatgat gcgggtacag attctatcgt tagtggattt tggttgagtg gcttatgtga
    32101 taactggggc tcatcaacag atacatggaa atggtgggaa aaacattata caaacacatt
    32161 tgaaactgga agagctaggg atatgagatc ctatgcatcg gaaccagaat caatgattgc
    32221 tatggaaatg atgaatgtat atactggggg aggcacagtt tataattttg aatgtgccgc
    32281 gtatacattt atgacaaatg atgtaccaac tccagcattt actaaaggta ttattccttt
    32341 ctttagacat gctatacaaa atccagctcc aagtaaggaa gaagttgtaa atagaacaaa
    32401 agctgtattt tggaatggag aaggtaggat tagttcatta aacggatttt atcaaggact
    32461 ttattcgaat gatgaaacaa tgcctttata taataatggg agatatcata ttcttcctgt
    32521 aatacatgag aaaattgata aggaaaagat ttcatctata ttccctaatg caaaaatttt
    32581 gactaaaaat agtgaggaat tgtctagtaa agtcaactat ttaaactcgc tttatccaaa
    32641 actttatgaa ggagatgggt atgctcagcg tgtaggtaat tcctggtata tttataatag
    32701 taatgctaat atcaataaaa atcagcaagt aatgttgcct atgtatacta ataatacaaa
    32761 gtcgttatcg ttagatttga cgccacatac ttacgctgtt gttaaagaaa atccaaataa
    32821 tttacatatt ttattgaaca attacaggac agataagaca gctatgtggg cattatcagg
    32881 aaattttgat gcatcaaaaa gttggaagaa agaagaatta gagttagcga actggataag
    32941 caaaaattat tccatcaatc ctgtagataa tgactttagg acaacaacac ttacattaaa
    33001 agggcatact ggtcataaac ctcagataaa tataagtggc gataaaaatc attatactta
    33061 tacagaaaat tgggatgaga atacccatgt ttataccatt acggttaatc ataatggaat
    33121 ggtagagatg tctataaata ctgaagggac aggcccagtc cctttcccaa caccagataa
    33181 atttaatgat ggtaatttga atatagcata tgcaaaacca acaacacaaa gttctgtaga
    33241 ttacaatgga gaccctaata gagctgtgga tggtaacaga aatggtaatt ttaactctgg
    33301 ttcggtaaca cacactaggg cagataatcc ctcttggtgg gaagtcgatt tgaaaaaaat
    33361 ggataaagtt gggcttgtta aaatttataa tcgcacagat gctgagactc aacgtctatc
    33421 taattttgat gtgattctat atgacaataa tagaaacgaa gttgctaaga aacatgttaa
    33481 taatttgtcg ggtgaatctg ttagtctaga tttcaaagaa aaaggagcaa ggtatattaa
    33541 agttaaatta ctaacgagtg gagtgccttt gagtttagca gaagtagagg tttttagaga
    33601 atcagatggt aagcaatctg aagaggatat agataaaata acagaagata aagtagtctc
    33661 tacaaataag gtagctactc aaagttcaac caattatgag ggtgtagctg ctttagcagt
    33721 tgatggtaat aaagatggag attacggaca tcattcggtg actcatacta aggcagattc
    33781 taacgcttgg tggcaggtcg atctgggaga agagtttacg gtttctaaag ttgatattta
    33841 taatagaaca gatgccgaac ctcagcgttt atctaatttt gatgttattt ttctatcttc
    33901 atcaggagaa gaagttttta gaagacattt tgataaagta gttgatggtt tgttatcttt
    33961 aaaagtacct tctgtagggg ctaagctagt caaaatagaa ttaaaatcag cagctattcc
    34021 gttaagttta gcggaagttg aagtctatgg ttcaaagaga actccgaaga aactttctaa
    34081 tattgcatta accaaagaaa ctcgacagag ttcaacggat tacaatggtt tttctcgtct
    34141 agcagttgat ggaaataaaa acggagatta tggtcatcat tcagtgactc ataccaaagg
    34201 agattctcct tcatggtggg agatagattt agcacaaacc gaagaattag aaaagttaat
    34261 tatttataat agaacagatg ctgaaattca gagattatca aattttgata ttattatata
    34321 tgattcaaat aatcatgaag tttttaaaca acatattgac agtttagaaa gcaataatct
    34381 atccatagac ttaaaagggc tgaagggaaa aaaggttaga atttctttga gaaacgcagg
    34441 aattccttta agtttggcag aggtagaggt ttatacttat aagtaatttt aaaaattatc
    34501 atcggtagta tgaaagaaac agaaaaataa gaggaaaata gtatgattca acatccacgt
    34561 attgggattc gtccgactat tgatggtcgt cgtcaaggtg tacgcgaatc acttgaagta
    34621 caaacaatga acatggctaa aagtgtggca gatttgattt caagcacatt gaaatatcca
    34681 gatggggaac ctgtggaatg cgtgatttct ccatctacta ttggccgtgt accagaggct
    34741 gcagcttccc atgagttgtt taaaaaatca aatgtttgcg caacaattac agttacacca
    34801 tgctggtgtt atggtagtga aactatggat atgtttccag atattcctca tgctatttgg
    34861 ggatttaatg ggacagaacg cccaggagct gtctatcttg cagctgtact agcttcacat
    34921 gctcaaaaag ggattccagc ctttgggatt tatggaagag atgttcagga agctagtgac
    34981 acagatattc cagaagatgt caaagaaaaa cttttacgct atgcgcgtgc agctcttgca
    35041 actggcttga tgagagacac tgcttaccta tcaatgggta gtgtttcgat ggggattggt
    35101 ggttctattg taaatccgga tttcttccaa gaatacctag gaatgcgaaa tgaatcggta
    35161 gatatgacgg agttcacgcg ccgtatggat cgtagtattt acgaccctga agagttcgaa
    35221 cgtgcgctca aatgggtgaa agaaaacgta aaagaaggat tcgaccataa ccgtgaagac
    35281 cttgttttaa gccgtgaaga aaaagataga caatgggaat ttgttattaa gatgttcatg
    35341 attggacgtg acttaatggt tggtaaccca agacttgctg aacttggttt tgaggaagaa
    35401 gcagttggtc accatgcttt agtagctggt ttccaaggtc aacgtcagtg gacagaccat
    35461 tttccaaatg gagattttat ggaaactttc ctcaatactc agtttgactg gaatggtatt
    35521 cgaaaaccat ttgtatttgc gacagagaat gattcactaa atggtgtgtc tatgctcttt
    35581 aattatctat taacaaatac tccacaaatc tttgctgatg tgcgtactta ttggagccca
    35641 gaggctgtta aacgtgtaac gggacatact ttagagggtc gtgctgcagc tggcttctta
    35701 catctaatca actctggttc ttgtacattg gatggtacag gtcaagctac tcgagatggc
    35761 aaacctgtta tgaaaccatt ctgggagttg gaagaaagtg aagtgcaggc tatgcttgaa
    35821 aatacagact tcccaccagc aaaccgcgaa tacttccgtg gaggaggatt ctcaactcgt
    35881 ttcttgacga agggggatat gccagtaaca atggtacgtc tcaatcttct aaaaggggtt
    35941 ggtccagtgc tacaaattgc agaaggttat acacttgaac ttcctgaaga tgttcaccat
    36001 actttagata atcgtacaga tccaggatgg ccaactactt ggtttgctcc acgtttgaca
    36061 ggaaaaggtg ctttcaagtc tgtctatgac gtcatgaata attggggagc taatcacgga
    36121 gccataacat atggacacat tggagcagac ttgattacct tggcttctat gttgagaatt
    36181 cctgtcaata tgcataatgt acctgaggaa gatatcttta gacctaaaaa ttggtcctta
    36241 tttggaacag aagatctaga atcagcagac tattgtgcat gtcagttgtt gggaccacta
    36301 cataaataaa acttgtttat ataggaggtg aacttacgtc cctcctatcc ttttaaaaag
    36361 atttgttaaa caattcacaa ataattaaaa acgaatacaa aaagtaatat aatgatgtta
    36421 aatagatagc gcggaggcgc aggaggaaaa ttatatggct acattttatg ttccggcagt
    36481 caaccttatt ggaaaaggtg ttgtaaatga agtgggtcct tatatcaagg aacttggcta
    36541 taaaaaggca cttttggtta cagataagta catcgaaggc agtgatattt tacctaaggc
    36601 tttaaaacca ctggatacag aaggaatcga atatgtcatc tttagcgatg tagagccaaa
    36661 ccctacttgt aaaaatgtca cagatggggt agctgctttg caagaacatg gctgtgactt
    36721 tatcatcagt cttggcgggg gttctccaca ggatgcagct agttgtattt ctatcatggc
    36781 tacaaatggt ggaaaaccac aggattatga agggcttcat aagtctgcta aaaaaggctt
    36841 gccagttgtg gctatcaata caacggcagg aacttctgca gaaatcacta ttaactatgt
    36901 gattactgat gaagaacgca aggttaagat ggtaatggtt gacaagaata gccttgctct
    36961 tatctctgtt aatgacccgg aactcatgct ttccaaacct aaaggcctga ctgctgctac
    37021 tggtatggat gctctgactc acgctgttga agctttggta acacctggtg cttatgatgt
    37081 aaccaagaaa ctgtctattg gtgctattga gcttatcaag gaatatcttc ctcgtgctgt
    37141 agaaaatgga catgatattg aagcgcgtga aggtatggtc aatgccatct tccttggtgg
    37201 tatgagcttt aataatgctg gtcttggtta tgttcactca atggctcacc aactcggtgc
    37261 agtatataat ttgccacatg gcgtgtgctg tgccatgttg ctaccagtta tagaacgtga
    37321 aaatgctaaa cgtgtaccag aagctttccg caatgttgcc aaagccttgg gacttcatgt
    37381 agaaggtaaa tcagatcaag aatgtgccga ttatgcgatt gctgagattg agaagctttc
    37441 tgagacagta ggtattccta agaaactgac tgaacttggt attgaagaaa aagatttcga
    37501 ctttgaatac ctttctaaga atgccttgat tgatgcctgc gcaccaggaa atccatttat
    37561 gccaacctta gaagaaacga ttgcctttta taaagagtta ttttagcaag agattggacg
    37621 acaataggac aattcacctc taattattga catttcagga aaaatcgcag taaaaacggc
    37681 acagccttct ttaaatgtgc tataatacta gaaaaatact tgtggaggtt ccattatggc
    37741 aatatttttc atgatttttc tgattgtttg tgtgctccta ttggtgatag tcacactgag
    37801 tacagtttat gtggttcgtc agcagtcggt ggcgattatt gaacgctttg ggaaatacca
    37861 aaaggttgct aatagcggta ttcatattcg cttgcctttt gggattgact cgattgcagc
    37921 acggattcag ttgcgcttgt tgcaaagtga tattgtggtt gagactaaga ccaaggacaa
    37981 tgtgttcgtt atgatgaatg tagcgactca gtaccgtgtc aacgagcaga gcgtgacaga
    38041 tgcttactat aaactcatac gtccagaatc tcagattaaa tcttatatcg aagatgctct
    38101 tcgctcttct gttccaaaat taaccttgga tgaattgttt gagaaaaaag atgagattgc
    38161 ccttgaggtt caacaccaag tagcagaaga aatgaccact tacggctaca ttatcgtgaa
    38221 aaccttgatt accaaggtcg aaccagatgc agaagttaag caatccatga atgaaatcaa
    38281 tgcggcgcaa cgtaagcggg tcgcagcaca agaattggcg gaagctgaca agattaaaat
    38341 tgtcactgca gctgaagcag aagcagaaaa agaccgcctt catggtgtgg ggattgccca
    38401 acaacgtaag gcgattgtgg atggattggc agagtctatc accgaactca aggaagccaa
    38461 tgttggcatg acagaagaac aaatcatgtc tatcctcttg accaaccagt atttggatac
    38521 cttgaatacc tttgcctcta aaggaaatca aaccatcttt ttaccaaata ctccaaatgg
    38581 tgtggatgat atccgaacac aaatcttgtc agcccttcgc gctgagaaga aataatagac
    38641 taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccttgccgta tagatgttac
    38701 tgacttcgtc agttctatct gcaacctcaa aacagtgttt tgagcaacct gtggctagtt
    38761 tcctagtttg ctctttgatt ttcattgagt gcaaagagct tggcaacagg ctctttttgt
    38821 attgcgttta ttaagaaaaa caaaaaacat cgatatacat ttaactaaaa attattgtat
    38881 gtcatctccc ttaattagga atgataaggg aataactaga aagatttgtg aatacaaact
    38941 atttctgata tacaaaatat acagtaataa tgaatgatgg gagatgggat gaaagaattt
    39001 caatttgaga gaaagcagcg tttttctttg aggaaatatg caataggagc ttgttcggtc
    39061 ttgctaggaa cgagtttatt ttttgctggt atgggtgctc agcctgtaca ggctacagaa
    39121 acgagttcag cactaatttc aagtcattat ttggatgagc aggatttatc tgaaaagctg
    39181 aaatctgagt tgcaatggtt tgaattagaa aacaagcttt tgaacttatg ggagcattag
    39241 gttactatga aggatttgtt ccttatgttt caaatcaata caaaaaccaa actgaagaag
    39301 aaggcaaacc gctatctgat aaatatattt tcgaaaaaat cttaggaaaa acatatgcag
    39361 ccttcaaaaa agatcaaatt aatgagcgtg tcgagaaatt aggtaagtta aaacctatta
    39421 caataaatta caacggaaaa tcagaagtaa ttgatagtaa agaaaaatta caaaagctta
    39481 tgaataaagc cgttaaagac gaagtggctc aaatatagta aaatgaaata agaacaggac
    39541 aaatcgatca ggacagtcaa atcgatttct aaaaatgttt tagaaggaga ggtgtactat
    39601 tctagtttca atatactata aaatcaggca ataccacggc taaaaagttt gagtttatcg
    39661 aaacaccagt gcaaaaactg aaaaaagcga tttataaagc tcatctcaaa gattcagatg
    39721 actttagacc agaaacatcc acataaatct ttttgaaagc tgtttgaagc tttgtccttg
    39781 ctttcttagt tcatagatct gaactttatc ttcataactc aatttcataa taaaacaccc
    39841 caaaagttag atttattctg tctaactttt ggggtgcagt tcattaatcg gtcgattttt
    39901 ttggtagaaa cagttgcctg attaagttgc aagtcgatag acggcttcgg cataaatatc
    39961 catagcacgg tacaaatctt ctagaacggc acattcattt gcctgatgtt ctgtctgctt
    40021 cgcttctggg aataaggcgc cgaaggctac acaatttggc atggtgcgag caaaagtggc
    40081 accaccggat gaaatagcag gactgttatc gccagtcttt tcttggtaga tttgcatcag
    40141 tgtgctaacg agtttactgt cttttgcgac gtatagaggc gctagatagt caaactcttc
    40201 gtagcggagt tggtagtttt gtgcacatct tgtaagcaac tttactagtt cttccttgtc
    40261 agctaagaca ggagtccgaa tgtcaatacg gatttcagaa cgttcatgat tgatcatgag
    40321 acctgcgaca ttaaaggata ggtgaccaga aggttcatct gctatatcac caaagatttg
    40381 tcttcctgtg ccgtcttgac ctgcttgtgt tgcaagaaaa ctgagagcag ggtgttcttg
    40441 gagaggagca agaatggtag ctagtcggat gacagcattg ataccttgac tagcatcctt
    40501 agcatgcttt ggcactccga gaaccgttac ggtttgttca gtggtttggt aatcataacc
    40561 agcttctttg ataccgttac aaacctgttc atagaggaga ccttggtagt tggccttgtc
    40621 tggtacaacg ttaaaggcgc ctcctacttc aagctctagt tgatccgatc cagggccatg
    40681 aagtttgacc tgtagaagcc ctttttcagc ataggtcaga ggaaaagatg agtcaggtgc
    40741 aaagcccata ctggcctgtt cttcgatggt attgtagcgt gccatgcagc gccagagggt
    40801 ttcctcatcg gtaccaaaga taaagcgtac gcgctttttg aactgaatac cttggtccag
    40861 caagcttttt actgcataga gagctgcgag cgaagggcct ttatcatctt ggacaccacg
    40921 tccgaatacc cagccgtctt tgatagttgc ttcaaatggc ggtgtctgcc aatctgcttc
    40981 atcacctgat ggaacaacat ccaaatgaca gagaatggcc agaagctctg ctccctgacc
    41041 gatttctgca tatccgtaat aacctttagg gtcaagatag gtagtgaaac ctatgtctcg
    41101 acaaatctct aaagtttttt ctaggacatc ttggattgct tgtccaaaag gtgttccatt
    41161 ttctccttca ttgagtactg aaggatagga aatcaaggtt tttaatgata taagaaattc
    41221 atctttaact tgatttgtta tatctatttt catggaatca cctcactcac tattttatag
    41281 gaatggaagg aaggttccaa ggagaagaag ggcgatggtc actacaataa tagcgactac
    41341 gagtttgccc atgaatttcc accaagtacc aatgttgata cgtccaagtg caagagctcc
    41401 catcacaata ccagatgttg gtgcaatcaa gttcaagaca cctgaagcag attggtaagc
    41461 agtgataatc aagctaggac ggacatttac aaattctcca agtggagcca tgatacccat
    41521 agttgcgctg gcaagaccag atgaagatgg gatcaagaat gacataggta gatagaagat
    41581 ataagttaca acgataaaga cttgtgaaga tagaccgctc aagccttctt taccccagtt
    41641 gaggattgta tcggtaatca taccgtcgtt catgataact tgaataccac gagcaatcgc
    41701 tacgatcaag gcaacactga gcaagtcagc agcaccattc atgaaggaag agataatctt
    41761 atcttcttta agaccataaa taacaccaat caggataccc ataaaggcaa agagcatggc
    41821 gccttctggg aagtaccaag tacctagtgc agaagtagat gaaccgacaa tattaccaat
    41881 aactggaaga ccagtcaacc aagcattaaa gtcatcaaaa atggtaacgc caaggtctgt
    41941 ccatggaatg aagctcaata ccatcaagat gaatgtcaac acaaataaga agagaactga
    42001 tttttgtttg ctgctaagtg tagattctac agatgaagat tcttctacgt taaagtgttt
    42061 caaatcttct ttgcgagtac tataaaccag tgacttagtc ggatcttttt gaatcttatc
    42121 cgcataacgg taaacaaacc aagtactaag agcagtcaag gtaacccaga agatcagacg
    42181 aagtacgata ccgtcccctg taccaactcc cgcagtcgct gaagcaatac ctgtcgcaaa
    42241 tggattcaga gtagatgcca aacagccgat ttgagaaccg agcaaaataa ttgcaacacc
    42301 agtcaggcta tcaaaaccaa cggccatcat aactggcaca aggagtggat agaaggccat
    42361 tgtttcttca cccataccat aagttgtacc accgagggca aacaaaggca tcagtaccaa
    42421 aattaacatt ttttcgcggc ccttatactt cttcacgata gaggcaatcc ctacgtcaag
    42481 agcaccagtt ttgttgacaa tgccaaggaa accaccaacc ataaggatga agaaggctac
    42541 atcaatcgct gcgctcgttt ctttaatgag cgaaccttcc tctggatgag tacctagcat
    42601 agcccgaatc ggtgccatga ggacatccca aatcccttgt ggattttgag gctgagcctc
    42661 gtaaatacct tctataaagg cccccgcagg gataaaccaa gttagcactg ccataatagc
    42721 aatgattatc aataatacgg tgtaagatga aggcatctta aacccttttt tagctttttc
    42781 actcatttgt ttttcctcct gatgtctaac aaagtgtaaa aaaccaacta ctttcttaaa
    42841 taaacattca agaaaacgct ttctatttat atttgtttta ccatattaaa gtctaaaact
    42901 agtatctttt gaaatattgt acatgttttc aagaataatt tctaatttga tataaagata
    42961 ctagaaatag aatacatctt attagtaaaa caacttatcc tttttcaata attgttccgc
    43021 tttcagattc aatcaaggcg cctagatttt caagggaagt aataactgct tttccttctg
    43081 gacgaccatt gacaaaagcg atagctgctt ctacttttgg aagcatgcta cctggtgcaa
    43141 actgatcttg tttgatatat tcttccagct gggcaacatt cacatgttcc aatttttcct
    43201 ggtttggctt gttgtagtta acaaatacat aatctacacc tgtcaaaatg atgaagaggt
    43261 ctgcatcaac caattctgcc aaacgttggg aagcgaagtc tttatcaata accgcttcga
    43321 caccagtcaa atgtccattg ttttctttga cgacgggaat accgccacca cctgcagcta
    43381 cgacgacttg accattattt aaaagagtac ggatggtttc aatttctttg atgtcaacag
    43441 gttttggtga ggcaacgacc ttacgccagc cacggccagc atcttccttg aaagtcgctc
    43501 cgctcttttc ggcttctgct tttgcttctt cttctgaata gaaaggaccg attggtttac
    43561 tcaagttaac aaaagccgga tcatttttat ctacgacaac ttgcgttaca acagaggcaa
    43621 catttttttc gatgccttca tccaagagag cattttgcaa agcatttttc aaccagaaac
    43681 cgatgctacc ttctgtcata gcgacaagtg agtcgagtgg gaaggcaggg ttcttttcag
    43741 agtctgatgc caaatgttgg agcaagagat tcccaacttg aggtccatta ccgtgagtga
    43801 taatcaaatc atctccattt ttaatcaatt ttacaagatg cttagctgtt tcaactaaag
    43861 cttcttgttg agcctttgct gatgggtcag aagaaagaat cgcatttcct cccaaagcta
    43921 ctacaatttt acgatttgcc ataaattctc ctttatcaca ctcaatagaa tgcgtttaga
    43981 tttcaattta atgatttttc acatatttta taagaaataa tagattacca ttatataaaa
    44041 gaggaccgga ctaaagctat tagtcgcagc cctcatagct gttggtagac ggtttattat
    44101 ctaaaattat actttaggaa tataaaggtt accaagtgta gcagccataa cagctttgat
    44161 agtgtgcata cggttttctg cttgatcgaa gtggcgagcg tacttgctgc ggaagacttc
    44221 gtctgttact tccatttctt ctacaccaaa tttttcagca acgtctttac cataaacagt
    44281 gtgagtatcg tggaatgctg gcaagcagtg taggaagatc aagttttcat tgcctgcttt
    44341 tttaactaag tccatattga cttggtaagg tttaagaaga gctacacgtt ctgcgaattt
    44401 gtcttcttca cccattgata cccaaacgtc tgtgtaaaga acgtctgcat ctttaactgc
    44461 ttcatcagca tcttcagtga tgagaacatg tgcgccactt tctttagcaa atccttctgc
    44521 caattcaacg atttcttttt ctgggaagag ttcttttggt gagaagatgt gaacattgac
    44581 accaaggata gcacctgtta cgagcaagct gttggcaacg ttgttacgtc catcaccaca
    44641 gtataccaat gtcaagcctt ccaagcgacc gaagttttct tgaacagtca agtagtcagc
    44701 gagcatttga gttgggtgcc attcgtcagt tagaccgttc catactggaa cgcctgagaa
    44761 ttctgccaat tcttcaacca tacgttggct gaatccgcgg aattcaatcc cgtcaaacat
    44821 acgtcccaat actttagcag tatcttcagt agattctttt ttgcccaact gaatatcatt
    44881 tgctccgagg tattctgggt gagcaccaag gtcgatagcc gcagttgtaa aggctgcacg
    44941 agtacgagta gatgtttttt caaataggag agcgatattc ttgccagcaa ggtagtggtg
    45001 ttgaatattg cgttttttca aatctttcaa gtgagctgaa agaccaataa ggtattctaa
    45061 ctctgcacgg gtaaagtctt tttctgctaa gaagctacgt ccttggaata ctgaatttgt
    45121 cattttatta tttcctcttt ctatttttta cattttctat tgacgaatac cgaacagcga
    45181 ttacacttct tcacgttcaa atggcataga catacaacga ggtccaccac ggccccgaac
    45241 caattcactt ccgcgaatct taatcaagcg aagcccgtat tcttccaaaa tcttattggt
    45301 cacggtattg cggtcataaa caactaccac accaggtgcg atggtcaaag tgttagaacc
    45361 gtcgttccat tgttcacgcg cagctgctac gatattgcca ccaccgcaac gaatcaaatg
    45421 aactttttct acaccaaggt tttgagcaag aagttcagct aagtcacctt tctcttcaac
    45481 gattttaagt ttttcgtttt cgtaagtaac tgagtaaacg tgaaggtcgc cttcgatttc
    45541 tgggtgaata gtgaacttgt catagtctac catagtgaag acagtatcca agtgcatgaa
    45601 tttacggttg ttagcaaatt caaaggccaa aactttcttg aagccaacat ttttcttgaa
    45661 gatgttgacc aaaagttttt cgatagaagc tgcgtctgta cgttgagaga tacctactgc
    45721 aaggacgtct ttagaaataa ctagctcgtc tccaccttcg atacgcgtat cttcttcacg
    45781 gttgtagacc aaatccactt ttccgccata gattgggtgg tatttgaaga tatacttacc
    45841 gtagagtgtt tcacggttac gagtgtctgc aaacatgtgg ttaagcgata cggcgtttcc
    45901 aattgttgca aatgggtcgc gagtgaaata gaggtttggc atcgggtcaa ttgcaaatgg
    45961 atactctgat tcaactaagt cagttagatc tttagcttcg tcaggaattt ctggcaattc
    46021 aactttttga atcccagcca ttgttttttc aaccaattct tggttgtcct tgatgccgtg
    46081 aagcaattca cgaatagcaa ccttggtttg acgatcacgg atgttggctt cgtctaagta
    46141 ttcctcgata aattgatcgc ggatttctgg agaggtcaat gattcagcag cgagttgttc
    46201 tagatagaga acctcaattc cttcatcgcg aagagcttgg gcaaatgcat catgttcttt
    46261 ttgagcatct tccaagaaag gaatatcatc aaaaagaagc ctttcaagat agtccggcaa
    46321 caagttttct aactccttgc ctggacggtg caacataact tttttcagtt tcccaatttc
    46381 tgagaagacc tgaattggat gtgaagacat gtattttcct ccttaaaaat tttgacttgg
    46441 caccattttg ggtaccgctt acatgtatgt tataacgcaa ttcctaggta atgtcaatgg
    46501 ctataatttc tcggaaaata atataaatta tgatatttag cacaatttta tgttattata
    46561 cataacatag gatggaatac atatatacaa atgcataaac ttctattaaa gaggatataa
    46621 aattttttta aaaaattttt caaaaaatat acaaatgacc aaaaagtgtc caattatcat
    46681 ctggttatca cttggatctg tataaagaga aatgtttgtg tgaaaggata aaaagatgca
    46741 acattctttt gaagatagat tttggagaag catttcttgt tcaattgtac aaattataga
    46801 atcttttctg agtatttagg aagagataat tatcttattg accctctttt tattttttgt
    46861 tatagtcgac gagatgatag tttagaataa tcacttattc acaatctgtg gaaaagtctg
    46921 gatagtgaat ggtcttcaca caatgacctg aaagaagcct gagaataatt atggagagta
    46981 gcattctgag aggtgttagc agaaccatat gacagagctg tttgaagagg gaacattgag
    47041 gagaaaaatc ctgagcctac cagttggagt tggaaagagc tggctgttag atcatggttt
    47101 attatccaca acctgtggat aatcttgtga acaagagaag ttgcaaaaga aggagatata
    47161 taacgatgaa gaaaatcaaa ccgcatggac cgttaccaag tcagactcag ctagcttatc
    47221 tgggagatga actagcagct tttatccact tcggtcctaa taccttttat gaccaagaat
    47281 gggggactgg acaggaggag cctgagcgct ttaacccgag tcagttggat gcgcgtgagt
    47341 gggttcgtgt gctcaaggaa acgggcttca aaaagttgat tttggtggtc aagcaccacg
    47401 atggctttgt cctttatccg acagctcaca cagattattc ggttaaggtc agtccttgga
    47461 ggagaggaaa gggcgacttg ctccttgaag tatcccaagc tgccacagag tttgatatgg
    47521 atatgggggt ctacctgtca ccgtgggatg cccatagtcc cctctatcat gtggaccgag
    47581 aagcggacta caatgcctat tatctggctc agttgaagga aatcttatca aatcctaact
    47641 atgggaatgc tggtaagttc gctgaggttt ggatggatgg tgccagagga gagggcgcgc
    47701 aaaaggttaa ttatgaattt gaaaaatggt ttgaaaccat tcgtgacctg cagggcgatt
    47761 gcttgatttt ttcaacagaa ggcaccagta tccgctggat tggcaatgaa cgagggtatg
    47821 caggtgatcc actgtggcaa aaggtgaatc ttgataaact aggaacagaa gcagagctga
    47881 actatcttca gcacggggat ccctcgggca cgattttttc aatcggagag gcagatgttt
    47941 ccatccgtcc aggctggttt taccatgagg atcaggatcc taagtctctc gaggagttgg
    48001 tcgaaatcta ctttcactca gtagggcgag gaactccact cttgcttaat attccgccga
    48061 atcaagctgg gctctttgat gcaaaggata ttgaacgact ttatgaattt gcgacctatc
    48121 gcaatgagct ctataaagaa gatttggctc tgggagctga ggtatctggt ccagctcttt
    48181 ccgcagactt tgattgtcgc catttgacag acggccttga gaccagctct tgggcaaacg
    48241 atgcagactt gcccatccag ttagaactcg atttaggttc tcctaaaact tttgatgtaa
    48301 ttgagttaag agaagatttg aagctagggc aacgaatcgc tgcttttcat gtgcaagtag
    48361 aggtggatgg tgtctggcag gagtttggca ggggcttcac agttggtcat aagcgcctct
    48421 tgcgaggtcc gctagtagag gcacaaaagg tgcgcgtgat gattaccgag gcacaatcta
    48481 tccctgtatt gaccaagatt tccctttata aaactcctgg gttatcaaaa aaagaagttg
    48541 ttcaggaact agcatttgca gaaaaaagcc tagctgtggc aaagggagag actcttcatt
    48601 ttaggattga acgtagtgaa agtagctcct ctttagaggc taagatttcg attcaaccgg
    48661 ggacaggtgt ccatggtgtc gcctatcagg acgagattta tgtccttgcg tttcaagctg
    48721 gtgagactga aaaaaggctg acgctaccaa ccttgtattt cgcaggagat aaaaccttgg
    48781 atttctatct gaacctaacg gtggatggtc agcttgtgga tcaacttcaa gtccaagttt
    48841 cataaaagaa gaacctttgc gcgatgcaaa ggttcttttg gttattagtg atttggtagc
    48901 cagctgaggg tgaaagttag ttgttcagct tttaggaggt cttggtgttg aatagttgat
    48961 acgagtgttt tgtccagtcg gcattctttg acaaagttaa aatggttgtg gttttgttta
    49021 gtatgaatat ctagccattt attttcttta gctaggtaga ctcgtagatg gtcaaagaga
    49081 ggaattccga gatcatagct tggttttcct ggacaggttg gataaaatcc gagagctgac
    49141 cagatgtacc aagcagagag actaccattg tcttcatctc caggataggc ttcccaactt
    49201 gggtgaaaag ctttctgacg gagcgtcttg ataagaaggg cagtgtagtc agggtaatcg
    49261 ctgtagcgga agagataagg aatgtggaaa ctaggctggt tggaaatggc tatttgtcca
    49321 aaaggagcag tagccatctc gctcatttcg tgaatttcgt aaccatagcc tgttgtttca
    49381 aagaggggag catcttgaca ggctttcaaa agatagttgc taaaggtttc ttttccaccc
    49441 atcagttgga ttaagccagg gatgtcgtgg agaacgccta aagtagcttg aatggcagag
    49501 cattcagcgt agtctcgccc ccaactataa ggagagaagt cagggtgaaa gtttccttga
    49561 ttgtctcgtg ctcgcatgta acctgtctca gcgtcaaata gctggcggta attttgtgaa
    49621 gcagccttgt aggtttcagc gatttctatg ttctctagtt ttttggcaca gctggcgata
    49681 caaaagtcac tataggcata gtctagagta tggctaacac tttcgtggtg gtcggtagag
    49741 aggtaaccta gttcttggta ttgggctagt ccgtggcggc cattgatgcc gagagggtcg
    49801 gctttgctgg ctgtttcgag catggcttgg aagagttctc cttctaggtc aggggccatg
    49861 tccttgcagg cgctatctgc gataataccg tctaaaagtg tacctggcat cataccccgt
    49921 tcatctggag ccagccattt tggaaggaaa ccagtatcgc ggtagctatt gaggaaacct
    49981 tctaaaaagc gttgatagtg ctccggtatg ataagggcaa agagggggaa ggtggtgcgg
    50041 aaggtatccc agaaaccatt gttgctaaag aggacaccag gcttgacagt accagtagcc
    50101 agatccatgt ggatggcttg ccctgactca tcaacctcat aaaaagtctg tgggaagagg
    50161 aagagtctgt agaggcagtg gtcaaagaag gttcggtcag cctctcctgt ctctataaca
    50221 tcaaaacgat ggaggagatt ttcccaatcc gcttgggcac ttgctttaca gctatcaaaa
    50281 tcttcttgag gtagattgat tagagcttga gaaggagaga tgaaagaagt ggctagttgc
    50341 atctcggttt gactacttac taagtcaatt cgccagtctc ccccttcttg gctgatagca
    50401 agaatatccg tgttcatttg tagggcagtg aacatcgtta gcgaattttt gttggtttca
    50461 gttttacctt cttgtcgcag ggcaagagtt cgcttatcta cttgctctac tgtcagttca
    50521 tctgctgcgt gaagatagag ggagagggct ttgccttgct tttgcttcaa acgaatagaa
    50581 gcaccgtagc aagtcggtgt gagctgggtt tcaatctgat agcgcaggga gaaaatcttt
    50641 agataatgag gttggaaaga ggccttatcc ctatcatagg aagattggcg gtgaaagaga
    50701 ctgtctcccc caagctgacc tgtgacaggt gtcagaagga gccaagagta gtccccaatc
    50761 caaggactgg gctggtgagt taatcgaatc ccctgaaaga taggcagatg cggatcaaaa
    50821 aaccaagatc catcctggtc actggtctgg ggcacaaagt aattcatccc aaaaggcacg
    50881 cctgtgtatg gcagggtatt tccccgagaa aaggcatgct tgttggtagt tccaaagcgg
    50941 gtatcgatgg tttcaagtag tggtttcata gtctttcctt tagctgtttt tctacattat
    51001 atcagaaaaa gagggccttt agaaaaggag tttcaaaaat aactattttg tagaaaaatg
    51061 actatcattt gtgtatgtat tttctgtctc aaaagctata tactgaacat gaaacttgtt
    51121 tgaaagaggg aattgcacga tgatttattc gaaagaaatt gttagagaat ggctagatga
    51181 agtagcagag cgggctaagg accatccaga gtgggtggat gttttcgagc gttgctacac
    51241 cgataccttg gacaatacgg ttgaaatctt agaagatggt tcaacttttg tcttgactgg
    51301 ggatattcct gccatgtggc ttcgagattc gacagcccaa ctcagaccct accttcatgt
    51361 agctaaaaga gatgccctcc tgcgtcagac cattgcaggt ttggtcaaac gtcagatgac
    51421 cttggtactc aaggatccct atgctaactc cttcaacatt gagaagaact ggaaagggca
    51481 ccacgagact gaccacacag accttaacgg ctggatctgg gagcgcaagt atgaggtgga
    51541 ttcactttgc tatcctttgc agttggctta tctcctctgg aaagagactg gcgagactgg
    51601 tcagtttgat gagacttttg tcgcagcgac taaggaaatt ctccatctat ggacagttga
    51661 acaagaccac aagaactctc cttatcgttt tgtccgagat acggaccgta aggaagacac
    51721 cttggtaaat gatggctttg gacctgactt tgcagtgaca ggtatgactt ggtcagcttt
    51781 tcgtccgagt gacgattgct gtcagtatag ttacttgatt ccgtctaata tgtttgccgt
    51841 agtagtcttg ggttatgtgc aagaaatctt tgtcgaatta gacctagctg atagccagag
    51901 tgttattgct gatgccaagc gtcttcagga tgaaatccaa gaaggaatcg aaaactacgc
    51961 ttacaccacc aacagcaagg gcgaaaagat ttacgctttt gaagtagatg gcctaggaaa
    52021 tgccagcatc atggatgatc caaatgtacc aagtttacta gctgcgccct atctgggcta
    52081 ctgttcggtc gatgatgaag tgtatcaagc tactcgtcgt accattttga gctctgaaaa
    52141 tccatatttc taccaaggag aatacgctag cggtctcgga agttctcata ccttctatcg
    52201 ctatatctgg ccaatcgccc tttctatcca aggattgaca acaagagata aggcagagaa
    52261 aaaattcttg ctggatcagc tggttgcctg cgatggtggt acaggtgtca tgcacgaaag
    52321 cttccacgtg gatgacccaa ctctctactc tcgtgaatgg ttctcctggg ctaacatgat
    52381 gttctgtgag ttggtcttgg attacttgga tattcgctaa ggggctcgct ttagctcaac
    52441 cgattcttat cagaatcaca agtttacatt taaaacgtta aaatttaaat ttagaatgag
    52501 gttttacttc atggaaaatg ttgttgtaca tattatctca catagtcact gggaccgtga
    52561 gtggtacttg ccttttgaaa gtcatcgtat gcagttggtg gaattgtttg acaatctctt
    52621 tgatctcttt gaaaatgacc ctgagttcaa gagtttccac ttggatggac aaactattgt
    52681 ccttgacgac tacttacaaa ttcgccctga aaatcgcgac aaggtccaac gctacattga
    52741 cgagggcaag cttaaaattg gtccctttta catcttgcag gatgattatt tgatttcaag
    52801 tgaagccaat gtccgcaata ccttgattgg tcaacaagaa gctgccaaat ggggtaaatc
    52861 aacccagatt ggctactttc cagatacctt tggaaatatg ggacaagcac ctcaaattct
    52921 tcaaaaatca ggcattcatg tggcggcctt tggtcgtggt gtgaagccga ttggatttga
    52981 caaccaagtc cttgaagatg agcagtttac atcccagttt tcagaaatgt actggcaggg
    53041 tgtggatggt agtcgtgttt taggtattct ctttgccaac tggtacagta atgggaatga
    53101 aatcccagtt gacaaagatg aggccttgac cttctggaaa caaaaattgt cagatgtgcg
    53161 tgcctacgct tcgaccaacc aatggttgat gatgaacggc tgtgaccacc agcctgtaca
    53221 gaaaaatctg agcgaagcca ttcgtgtggc aaatgaactc ttcccggatg taatctttgt
    53281 tcatagttct tttgatgaat atgttcaagc tgtagaaggt gcgcttcctg aacacttatc
    53341 aactgttaca ggcgagttga ccagtcagga aacagatggc tggtacacac ttgccaacac
    53401 ttcttcatcc cgcatttacc taaaacaagc cttccaagaa aatagcaacc tcctagagca
    53461 agtggtagaa cccttgacta ttatcactgg tggacacaac cacaaggacc agttgaccta
    53521 tgcttggaaa acacttttgc agaacgcgcc acatgatagt atctgtggct gtagcgtgga
    53581 cgaagttcac cgcgagatgg aaacgcgttt tgccaaggtc aaccaagtag gaaactttgt
    53641 taaaagtaac ttgctcaacg agtggaaggg taaaattgct acggataagg ctcaaagtga
    53701 ctatctcttt actgtcatta acacaggctt gcatgataag gtcgatactg tcagcacagt
    53761 gattgatgtg gcgacttgtg atttcaagga attgcaccca acagaaggct acaaaaagat
    53821 ggctgctctt atcttgccaa gttaccgtgt ggaggacttg gatggtcgtc ctgtagaggc
    53881 tacaatcgaa gacctcggag ctaattttga gtacgattta ccaaaagata agttccgcca
    53941 agctcgtatt gctcgacaag tgcgcgtgac cattccagtt cacctagcgc cgctttcttg
    54001 gacaaccttc caattgctgg aaggaaaaca agaacaccgt gagggtattt accaaaacgg
    54061 agtgattgat acaccattcg taacggtgag tgtggatgac aacatcacag tctatgacaa
    54121 gacaactcac gaagcctatg aagactttat ccgctttgaa gaccggggtg acatcggaaa
    54181 cgagtatatc tatttccaac caaaaggaac agagccaatc tttgcagagc ttaaggacca
    54241 cgaggtcttg gaaaacacag atcgctatgc taaaatcttg ctcaaacatg aattgaccgt
    54301 gcctgtcagt gcggatgaaa agctagaaga agagcaacaa ggtatcatcg agtttatgaa
    54361 gcgtgaggct ggacggtcag aagaattgac aaacattcct ctggaaactg agttgactgt
    54421 cttcgttgac aatccacaaa tccgcttcaa gactcgcttt actaacactg ccaaggatca
    54481 ccgtatccgt ctcttggtca agactcataa cacgcgtcca agcaatgatt ctgaaagtat
    54541 ctatgaggtg gtgacacgac caaacaaacc agctgcttca tgggaaaacc ctgaaaatcc
    54601 tcaacaccaa caagcttttg tcagtctgta tgacgatgaa aaaggggtga ctgtatccaa
    54661 caagggattg aatgaatacg aaatccttgg ggataacacc attgccgtga ccattttgcg
    54721 tgcatcaggt gagctaggtg actggggcta cttcccaacg ccagaagcac aatgcttgcg
    54781 ggagtttgaa gtcgagtttg cacttgaatg ccaccaagcc caagaacgct tctcagccta
    54841 tcgtcgtgcc aaagccttgc agacaccgtt taccagcctt cagcttgcta gacaggaagg
    54901 aagcgtggtt gcgactggta gcctcttgag ccattctgtt ctcagcatac cgcaagtttg
    54961 tccaacagcc tttaaggtag ctgaaaatga agaaggctat gtgcttcgtt actacaatat
    55021 gtgtagtgaa aatgtacgtg tgccagaaag tcaacatctc ttccttgacc tacttgaacg
    55081 accataccca gttcattcag gactattggc tccacaagag attcgtacag aattcatcaa
    55141 aaaagaagaa atttaatttc aaaaagtaaa catcaaaaga aaggaggggc gaaaaagtaa
    55201 gaactaactg ctgattcgcc ccttttatgg taaaaacaat gaccattgca acgattgata
    55261 tcggagggac tgggattaag tttgccagtc tgactcctga tgggaaaata ctggataaga
    55321 caagtatttc aacgcctgaa aacttggagg atttactagc gtggctagat caacgcttgt
    55381 cagaacagga ttacagtggg attgctatga gcgttccagg tgcagtcaat caagagacag
    55441 gtgtgattga tggcttcagt gcggtgccct acatccatgg cttttcttgg tatgaggcgc
    55501 ttagctctta tcagctacct gtccatttag aaaatgatgc caactgcgtt ggactcagtg
    55561 aactactagc tcatccagag cttgaaaatg cagcctgtgt cgtgattggg acagggattg
    55621 gcggagccat gattatcaat ggtagacttc atcgaggtcg ccacggtctg ggtggagaat
    55681 ttggctacat gacaaccctt gcccctgctg aaaaacttaa taactggtcg caactagcat
    55741 caactgggaa tatggtacga tacgtgattg aaaaatctgg tcatactgat tgggacggtc
    55801 gcaagattta ccaagaggcc gcagctggta atatcctttg tcaagaagcc attgagcgca
    55861 tgaaccgcaa tctggcgcaa ggcttgctca atatccagta tctgatcgat ccagatgtca
    55921 tcagtctggg tggctctatc agtcaaaatc cagattttat ccaaggtgtc aagaaggctg
    55981 ttgaagactt tgtcgatgcc tacgaagaat acacggtcgc accagttatc caggcctgca
    56041 cctatcacgc agatgccaat ctctacggtg ctcttgtcaa ctggctacag gaggaaaagc
    56101 aatggtaaga tttacaggac ttagtctcaa acaaacgcaa gctattgagg ttttaaaagg
    56161 tcacatttct ctaccagatg tggaagtggc tgtcactcag tctgaccaag catctatctc
    56221 tatcgagggt gaggaaggtc actatcaatt gacctaccgc aaacctcacc aactttatcg
    56281 tgccttgtcc ttgttggtaa cagttctagc agaagctgat aaagtagaga ttgaggaaca
    56341 agcagcttac gaagatttgg cttacatggt tgactgttct cgaaatgcgg tgctgaatgt
    56401 ggcttctgcc aagcagatga ttgagatatt ggctctcatg ggctactcaa cctttgagct
    56461 ttacatggaa gacacttacc agattgaagg gcagccttac tttggctatt tccgtggagc
    56521 ttattcagca gaggagttgc aggaaatcga agcctatgcc caacagtttg acgtgacctt
    56581 tgtaccatgc atccagacct tggcccactt gtcggccttt gtcaaatggg gtgtcaagga
    56641 agtgcaggag ctccgtgatg tagaggacat tcttctcatt ggcgaagaaa aggtttatga
    56701 cttgattgat ggcatgtttg ccacgttgtc taaactgaag actcgcaagg tcaatatcgg
    56761 gatggacgaa gcccacttgg ttggtttggg acgctacctg attctgaacg gtgttgtgga
    56821 tcgtagtctc ctcatgtgcc aacacttgga gcgcgtgctg gatattgctg acaaatatgg
    56881 tttccactgc cagatgtgga gtgatatgtt cttcaaactc atgtcagcgg atggccagta
    56941 cgaccgtgat gtggaaattc cagaggaaac tcgtgtctac ctagaccgtc tcaaagaccg
    57001 tgtgactctg gtttactggg attattatca ggatagcgag gaaaaataca accgtaattt
    57061 ccgcaatcat cacaagatta gccatgacct tgcatttgca gggggagctt ggaagtggat
    57121 tggctttaca cctcacaacc attttagccg tctagtggct atcgaggcta ataaagcctg
    57181 ccgtgccaat cagattaaag aagtcatcgt aacgggttgg ggagacaatg gtggtgaaac
    57241 tgcccagttc tctatcctac caagcttgca aatctgggca gaactcagct atcgcaatga
    57301 cctagatggt ttgtctgcgc acttcaagac caatactggt ctaacggttg aggattttat
    57361 gcagattgac cttgccaacc tcttaccaga cctaccaggc aatctcagcg gtatcaatcc
    57421 caaccgctat gttttttatc aggatattct ttgtccgatt cttgatcaac acatgacacc
    57481 tgaacaggac aaaccgcact tcgctcaggc tgctgagacg cttgctaaca ttaaagaaaa
    57541 agctggaaac tatgcctatc tctttgaaac tcaggcccag ttgaatgcta ttttaagtag
    57601 caaagtagat gtgggacgac gcattcgtca ggcctaccaa gcggatgata aagaaagttt
    57661 acaacaaatc gccagacaag aattaccaga acttagaagc caaattgaag acttccatgc
    57721 cctctttagc caccaatggc tgaaagaaaa caaggtcttt ggtttggata cagttgacat
    57781 ccgtatgggc ggactcttgc aacgcatcaa acgagcagaa agccgtatcg aggtttatct
    57841 ggctggtcag cttgaccgca tcgacgagct ggaagttgaa atcctaccat ttactgactt
    57901 ctacgcagac aaggatttcg cagcaactac agccaaccag tggcatacca ttgcgacagc
    57961 gtcgacgatt tatacgactt aatattcttc gaaaatctct tcaaaccacg tcagcttcca
    58021 tctgcaacct caaaacagtg ttttgagcaa cctgcagcta gcttcctagt ttgctctttg
    58081 attttcattg agtataaaaa caagaacacc ttgcttggcg cagggtgttt cgcgtgaaac
    58141 agaagaatta tctggtttca aatgctacag ttagacaaac ttatgataaa atagcagaaa
    58201 gtgaatgttt cctaagagca attggaggta ttatgctaca cttaaaatta gtaaaacaag
    58261 aaatagaagc tgaaaagcca gcatctgtag aagcttggat catttccgtc aaatttaaaa
    58321 aaggttgcta ccgacatata tagattccaa aaacaaaaac gttagcggaa ctagcagatg
    58381 tgattttatg gagttttgat tttgcaaatg atcatgctca cgcatttttc atggataatg
    58441 ttgagtggag tcatgcagat tcttactttc gtagctttgt tagtgacgat gttgaagaac
    58501 gttacacaga aaatgtctat ctggatagcc taagtgtcaa acaaaaattt aagtttattt
    58561 tcgacttcgg tgatgaatgg cgttttgaat gccaagtgct gagagaaatc gagacagagg
    58621 acgaagaagc ttatctcgta cgttcggttg gaacgtcgcc agaacaatat ccagattatg
    58681 atggttttga ctatgaagaa tggtaaaatt gaaatcagtc tgtgtaggct tagtatttca
    58741 atagacttcc tgcaaaacta gaatcctagt tcatgattga taatgccagc aaccaaattc
    58801 attcgtaatc cgaagcgttt acgatgattt cgataggttg ttgaaaacat tttaaacgtt
    58861 tttactttgg caaagatgtt ctcaaccttg cttctctcct tagatagcgc atggttatag
    58921 gctttatctt cagctgttag tggcttgagt ttgctggatt tacgtgaagt ttgtgcttga
    58981 ggacatatct tcatgagccc ttgataacca ctgtcagcca agattttacc agcttgtccg
    59041 atatttctgc aactcatttt gaacaacttc atatcatgac aatagttcac agtgatatcc
    59101 aaagaaacaa ttctcccttg acttgtgaca atcgcttgag ccttcatagc gtgaaatttc
    59161 tttttaccag aatcattcgc taattctttt tttagggcga ttgattttta cttccgtcgc
    59221 atcaatcatt accgtgtcct cagaactaag aggagttctt gaaatcgtaa caccactttg
    59281 aacaagagtt acttcaaccc attggctccg acggattaag ttgctttcgt gaataccaaa
    59341 atcagccgca atttcttcat aagtgcggta ttctaggctt aatttaggtt ttcgtccacc
    59401 ttttgcgtgt ttaagttgat aagctgtttt taatacagct aacatctctt taaaagtcgt
    59461 gcgctgaaca ccaacaagac gcttaaatcg tgtatcagtt aattgtttac ttgcttcata
    59521 atttcgcagg gagtctattg actctttggt aggtgtcaat gtttttttca tctatcccga
    59581 gaattatttt cccgccattt gtatttgcaa atgctgagta ggtttcccag aaagactctg
    59641 gaagattgtt tttagctttt ttgtattcta aatcaacccc ttcaaatttt aagtccatat
    59701 ttttccttta catctgtttt ttgtggttct ggtatttgtt caagttgagt gataatatag
    59761 cgaattgaat ttcgagagtt tttactcagt taatttcttt tttaacccac tttaatttct
    59821 tttttaacac gggttaaaaa agaaattaaa gtgggttaat ttttcttgac ttaaaattta
    59881 aaaatgatat actgtgttta tggagagatg acaatttata aaatgtacta ctctattcta
    59941 ctagataatg attgaataaa actttttata acaacggcta gcaaagttat aattttatat
    60001 ctattagaaa ataaatatgt aaggaaattt aaatgaaaaa aactacaata ttatcattaa
    60061 ctacagctgc ggttatttta gcagcatatg tccctaatga accaatccta gcagatactc
    60121 ctagttcgga agtaatcaaa gagactaaag ttggaagtat tattcaacaa aataatatca
    60181 aatataaggt tctaactgta gaaggtaaca taggaactgt tcaagtgggt aatggagtta
    60241 ctcctgtaga gtttgaagct ggtcaagatg gaaaaccatt cacgattcct acaaaaatca
    60301 cagtaggtga taaagtattt accgttactg aagtagctag tcaagctttt agttattatc
    60361 cagatgaaac aggtagaatt gtctactatc ctagctctat tactatccca tcaagcataa
    60421 aaaaaataca aaaaaaaggc ttccatggaa gtaaagctaa aactattatt tttgacaaag
    60481 gcagtcagct ggagaaaatt gaagatagag cttttgattt ttctgaatta gaagagattg
    60541 aattgcctgc atctctagaa tatattggaa caagtgcatt ttcttttagt caaaaattga
    60601 aaaagctaac cttttcctca agttcaaaat tagaattaat atcacatgag gcttttgcta
    60661 atttatcaaa tttagagaaa ctaacattac caaaatcggt taaaacatta ggaagtaatc
    60721 tatttagact cactactagc ttaaaacatg ttgatgttga agaaggaaat gaatcgtttg
    60781 cctcagttga tggtgttttg ttttcaaaag ataaaaccca attaatttat tatccaagtc
    60841 aaaaaaatga cgaaagttat aaaacgccta aggagacaaa agaacttgca tcatattcgt
    60901 ttaataaaaa ttcttacttg aaaaaactcg aattgaatga aggtttagaa aaaatcggta
    60961 cttttgcatt tgcagatgcg attaaacttg aagaaattag cttaccaaat agtttagaaa
    61021 ctattgaacg tttagccttt tacggtaatt tagaattaaa agaacttata ttaccagata
    61081 atgttaaaaa ttttggtaaa cacgttatga acggtttacc aaaattaaaa agtttaacaa
    61141 ttggtaataa tatcaactca ttgccgtcct tcttcctaag tggcgtctta gattcattaa
    61201 aggaaattca tattaagaat aaaagtacag agttttctgt gaaaaaagat acatttgcaa
    61261 ttcctgaaac tgttaagttc tatgtaacat cagaacatat aaaagatgtt cttaaatcaa
    61321 atttatctac tagtaatgat atcattgttg aaaaagtaga taatataaaa caagaaactg
    61381 atgtagctaa acctaaaaag aattctaatc agggagtagt tggttgggtt aaagacaaag
    61441 gtttatggta ttacttaaac gaatcaggtt caatggctac tggttgggtt aaagacaaag
    61501 g
//
LOCUS       DAVDHC010000012        48500 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVDHC010000012 DAVDHC010000000
VERSION     DAVDHC010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.012"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..789
                     /locus_tag="VUR43_001003"
     CDS             <1..789
                     /locus_tag="VUR43_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5412707.1"
                     /translation="GNGRIMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMA
                     DYRLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWG
                     ISREQFKQDIENGLSAATGWQKNGTGYWYVHSDGFYPKDKFEKINGTWYYFDGSGYML
                     SDRWKKHTDGNWYWFDNSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAK
                     EGAMVSNAFIQSADGTGWYYLKPDGSMADKPEFTVEPDGLITVK"
     gene            complement(1042..2010)
                     /locus_tag="VUR43_001004"
     CDS             complement(1042..2010)
                     /locus_tag="VUR43_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET5412708.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLAKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            2146..3003
                     /locus_tag="VUR43_001005"
     CDS             2146..3003
                     /locus_tag="VUR43_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET5412709.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERW
                     LGGWKHEKK"
     gene            2990..3769
                     /locus_tag="VUR43_001006"
     CDS             2990..3769
                     /locus_tag="VUR43_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET5412710.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            3793..5145
                     /locus_tag="VUR43_001007"
     CDS             3793..5145
                     /locus_tag="VUR43_001007"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET5412711.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KVIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            5219..5593
                     /locus_tag="VUR43_001008"
     CDS             5219..5593
                     /locus_tag="VUR43_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET5412712.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            5595..6443
                     /locus_tag="VUR43_001009"
     CDS             5595..6443
                     /locus_tag="VUR43_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET5412713.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGMIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGSGSIAL
                     GYIPVI"
     gene            6720..7487
                     /locus_tag="VUR43_001010"
     CDS             6720..7487
                     /locus_tag="VUR43_001010"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET5412714.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDSDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEEPIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            7499..8683
                     /locus_tag="VUR43_001011"
     CDS             7499..8683
                     /locus_tag="VUR43_001011"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET5412715.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            8680..10551
                     /locus_tag="VUR43_001012"
     CDS             8680..10551
                     /locus_tag="VUR43_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5412716.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(10694..11878)
                     /gene="mntE"
                     /locus_tag="VUR43_001013"
     CDS             complement(10694..11878)
                     /gene="mntE"
                     /locus_tag="VUR43_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET5412717.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSATKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            12182..14878
                     /locus_tag="VUR43_001014"
     CDS             12182..14878
                     /locus_tag="VUR43_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET5412718.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVDLATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            14891..15682
                     /gene="yghU"
                     /locus_tag="VUR43_001015"
     CDS             14891..15682
                     /gene="yghU"
                     /locus_tag="VUR43_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET5412719.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKFNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYATEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            15798..16208
                     /locus_tag="VUR43_001016"
                     /pseudo
     CDS             15798..16208
                     /locus_tag="VUR43_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
     gene            16220..17815
                     /locus_tag="VUR43_001017"
     CDS             16220..17815
                     /locus_tag="VUR43_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412720.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            17882..18046
                     /locus_tag="VUR43_001018"
     CDS             17882..18046
                     /locus_tag="VUR43_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET5412721.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            18125..18853
                     /gene="yaaA"
                     /locus_tag="VUR43_001019"
     CDS             18125..18853
                     /gene="yaaA"
                     /locus_tag="VUR43_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET5412722.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(19131..19679)
                     /locus_tag="VUR43_001020"
     CDS             complement(19131..19679)
                     /locus_tag="VUR43_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET5412723.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            20000..20488
                     /locus_tag="VUR43_001021"
     CDS             20000..20488
                     /locus_tag="VUR43_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET5412724.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISGSFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQAVQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            20485..21672
                     /locus_tag="VUR43_001022"
     CDS             20485..21672
                     /locus_tag="VUR43_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5412725.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVEKDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVENMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKGME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVKRLKVFMGS
                     END"
     gene            21665..22030
                     /locus_tag="VUR43_001023"
     CDS             21665..22030
                     /locus_tag="VUR43_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5412726.1"
                     /translation="MIDHFEIKVKDLQISEDFYRRFLAPLGYKLAFKTTSLISFLAPN
                     SPHPGGDFWLAQGTQDPIHFAFLAENKEEVQACYEAGLEAGGRDNGAPAYRSEQPIYY
                     AAFMIDPDGNNIEVVCHKE"
     gene            22050..23393
                     /gene="asnS"
                     /locus_tag="VUR43_001024"
     CDS             22050..23393
                     /gene="asnS"
                     /locus_tag="VUR43_001024"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET5412727.1"
                     /translation="MTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAF
                     FQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITDI
                     EVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVMQIRNAIIYATYEFFDKNGFM
                     KFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAE
                     KSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTEL
                     LKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPTF
                     VMNYPAAIKAFYMKPVPGNLERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDELG
                     MDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            23546..23836
                     /locus_tag="VUR43_001025"
     CDS             23546..23836
                     /locus_tag="VUR43_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET5412728.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            23848..24318
                     /gene="ssbA"
                     /locus_tag="VUR43_001026"
     CDS             23848..24318
                     /gene="ssbA"
                     /locus_tag="VUR43_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET5412729.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            24350..24589
                     /locus_tag="VUR43_001027"
     CDS             24350..24589
                     /locus_tag="VUR43_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET5412730.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            24883..26283
                     /locus_tag="VUR43_001028"
     CDS             24883..26283
                     /locus_tag="VUR43_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET5412731.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDHRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            26285..26644
                     /locus_tag="VUR43_001029"
     CDS             26285..26644
                     /locus_tag="VUR43_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET5412732.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            26698..27447
                     /locus_tag="VUR43_001030"
     CDS             26698..27447
                     /locus_tag="VUR43_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET5412733.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            27437..27736
                     /locus_tag="VUR43_001031"
     CDS             27437..27736
                     /locus_tag="VUR43_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET5412734.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            27807..28742
                     /locus_tag="VUR43_001032"
     CDS             27807..28742
                     /locus_tag="VUR43_001032"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET5412735.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            28828..29340
                     /locus_tag="VUR43_001033"
     CDS             28828..29340
                     /locus_tag="VUR43_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET5412736.1"
                     /translation="MLENGDVIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            29377..29640
                     /locus_tag="VUR43_001034"
     CDS             29377..29640
                     /locus_tag="VUR43_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HET5412737.1"
                     /translation="MIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILRENKR
                     YYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRN"
     gene            29689..29973
                     /locus_tag="VUR43_001035"
                     /pseudo
     CDS             29689..29973
                     /locus_tag="VUR43_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811881.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            30074..30268
                     /locus_tag="VUR43_001036"
     CDS             30074..30268
                     /locus_tag="VUR43_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET5412738.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVSKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(30314..31759)
                     /locus_tag="VUR43_001037"
     CDS             complement(30314..31759)
                     /locus_tag="VUR43_001037"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET5412739.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGTTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            31865..33487
                     /locus_tag="VUR43_001038"
     CDS             31865..33487
                     /locus_tag="VUR43_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET5412740.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLAMGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKVQADRLRAKFKLS"
     gene            33692..35650
                     /locus_tag="VUR43_001039"
     CDS             33692..35650
                     /locus_tag="VUR43_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5412741.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGI
                     KALDDQTVQYTLARPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPANILYSGPFL
                     MKAFVSKSVIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTKMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            35822..37504
                     /locus_tag="VUR43_001040"
     CDS             35822..37504
                     /locus_tag="VUR43_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412742.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVTEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENR
                     PVLKDITCSIFKGQKIAFVGPSGSGKSTIVRLLEQFYKPLSGDILMEQSSIYDFNLKE
                     WRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDT
                     EVGERGRLLSGGRSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEK
                     TVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            37662..38756
                     /locus_tag="VUR43_001041"
     CDS             37662..38756
                     /locus_tag="VUR43_001041"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET5412743.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLATIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            38764..39930
                     /locus_tag="VUR43_001042"
     CDS             38764..39930
                     /locus_tag="VUR43_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5412744.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLLEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            40023..43121
                     /locus_tag="VUR43_001043"
     CDS             40023..43121
                     /locus_tag="VUR43_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5412745.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADSHQIYVTSY
                     AIFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLSAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            43169..43786
                     /locus_tag="VUR43_001044"
     CDS             43169..43786
                     /locus_tag="VUR43_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET5412746.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            43797..45131
                     /locus_tag="VUR43_001045"
     CDS             43797..45131
                     /locus_tag="VUR43_001045"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET5412747.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            45141..45605
                     /locus_tag="VUR43_001046"
     CDS             45141..45605
                     /locus_tag="VUR43_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412748.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            45602..46096
                     /locus_tag="VUR43_001047"
     CDS             45602..46096
                     /locus_tag="VUR43_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412749.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            46177..47832
                     /gene="mltG"
                     /locus_tag="VUR43_001048"
     CDS             46177..47832
                     /gene="mltG"
                     /locus_tag="VUR43_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET5412750.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSTEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            47903..48385
                     /gene="greA"
                     /locus_tag="VUR43_001049"
     CDS             47903..48385
                     /gene="greA"
                     /locus_tag="VUR43_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET5412751.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        14332 a         9162 c        11067 g        13939 t
ORIGIN      
        1 ggaaacggtc gcatcatgca ggtaggacct gtgaacaacg gaagttggga tgttgggggc
       61 ggttggaatg ctgagaccta tgcagcggtt gaactgattg aaagccattc aactaaggaa
      121 gagtttatgg ctgactatcg cctctatatc gaattgctac gcaatctagc ggacgaagca
      181 ggcttgccga agactcttga tacagacgac ttggcaggta tcaagacgca tgaatactgt
      241 accaataacc aaccaaacaa ccactcagac cacgttgacc cttatccata tcttgcaagt
      301 tggggcatta gccgtgaaca gtttaagcaa gacatcgaaa acggcttgag cgctgcaaca
      361 ggctggcaga aaaatggcac tggctactgg tacgtacact cagacggctt ttatccaaaa
      421 gataagtttg agaaaatcaa cggtacctgg tattatttcg atggctcagg ctatatgctt
      481 tcagaccgct ggaagaagca cacagacggt aattggtact ggttcgacaa ctcaggcgaa
      541 atggccacag gctggaagaa aatcgctgag aagtggtact attttgatgt agaaggtgcc
      601 atgaagacag gctgggtcaa gtacaaggac acctggtact acttagacgc taaagaaggc
      661 gccatggtat caaatgcctt tatccagtca gcggacggaa caggctggta ctacctcaaa
      721 ccagacggta gcatggcaga caagccagag ttcacagtag agccagatgg cttgattaca
      781 gttaaataaa tagaaaggaa actttctaaa ttgttctttc accgcaggct caggcttgcg
      841 gtttttttgt ttgctcaaaa ggggcaaaaa aggggcaaaa gtgtcgtaaa tctctgtaaa
      901 atgatgtaaa aacatttatt taaaagctca aaatatagct gttttaaaag gtattgtaag
      961 atatagtaaa acgatgtaaa ggtattttta aatgcggatg aattataaaa ccacgaatcc
     1021 tatgtgactc gtggttcttt tttataaact agtagagtgt tttggttgta ctttttgttc
     1081 agggtcaatg tagttgatag cgttgttgac agcagttgga gcttctccga ggcctgtcgc
     1141 aatcagatca atttttccgt catagtagca gcagtcaccg atagcataga tacctgcttg
     1201 gctggattcc tgtttgctgt tgacgataat cttgtgacgg ttgaggtcga gcccccagtt
     1261 tttaaggtta ccgacagaag atttgaaacc atagttgaca aagaggtggt ctaggtcaat
     1321 ggtttcagtt tcatcagatt tgacttttgt gatttcaagt ttagcaagtg tttttccatt
     1381 tccaaggagt tggctagggg cgaatggtgt cttgatggtt acagatgatt cttgcaaggc
     1441 ttgaacactg tgttccaagg cacggaaatt atctctgcgg tgaacaaggg tagttggtgc
     1501 gattttttca aaagccaaag cccaatccac agccgagtct cccccaccaa gaatcgtcac
     1561 tttcttacca gcgtattgct gaatgttaga aacgtggtag tggatatttt catagccctc
     1621 aacaccttca agttccagcg gacgtggttt gaaggcaccg ccacccatag cgatgataac
     1681 tgttttagtc aggtgacttc ctttagaagt tgtgatggca aattcttctt cttgtttgtc
     1741 aatctcaaga accgtttcat tgagatgaat aggggtatca aatccattta gctgttcaat
     1801 caagcggtta gtcaactctt ctccagtcag gtttgggaag cctggtacgt ctaggatttc
     1861 cttttcaggg tagagaatag caggttgtcc acctagctgg ggaagagagt cgatgatttg
     1921 aaccttggct tggcgtaggt gggcataaaa ggctgcaaaa agcccgacag gaccaccacc
     1981 cacaatggta atatcataga gttgagacat agtttctcct ttgttttttc tagtcagttt
     2041 attttatcat atttttgttc aatgtaaaat ggactaggat agggaaaaaa atgcccgaaa
     2101 atggtataat aggacgaaag tgttttgata gggaggatat cagggatgaa ttttcaacaa
     2161 ttatccaatc tgcaatattg gaccagtttg tttgcaagtc catggacgat agctatcaat
     2221 ctgattgata ttttgattgt tgcttatatt ttataccatt ttacaaaagc tattgcagga
     2281 accaagatta tgattttggt acgtggagtt ttggtattta ttttagctca aatccttgca
     2341 aatatgattg gtttgactac gatttcttgg ttaatcaatc aaattattac ttatggggtt
     2401 attgcggcgg ttgttatctt ctctccagag attcggactg gtttggaacg tttgggaaga
     2461 gcgacagatt tcttttccaa tgcccctatt agtgctgagg aacagatgat tcgtgccttt
     2521 gttaagtctg ttgaatacat gagtcctcgt aaaatcgggg ccttggttgc tattcagcgt
     2581 gtacgtacct tgcaggagta tatttcgaca ggaatcccct tggatgctaa gatttctgca
     2641 gaacttctca ttaacatttt tattcccaac actcccctac atgacggtgc ggtgattatc
     2701 aaagaagaac gtatcgctgt gacgtctgcc tatctgccct tgacaaaaaa cacaggtatt
     2761 tccaaggaat ttgggaccag acaccgggcg gctatcggtt tatcagaagt ctcagatgcc
     2821 ttgacttttg tcgtatcaga ggaaacggga ggaatttcga taacctataa tggaaggttt
     2881 aagcacaacc taacacttga tgaatttgaa acagaattac gtgaaatctt acttccaaaa
     2941 gaggaagtgg gtcttagttt taaagaacga tggctaggag gatggaaaca tgaaaaaaaa
     3001 tagtttatat atcatatcct cactcttttt tgcttgtgtc ttatttgtct atgctacggc
     3061 gacgaatttt caaaacagta ccagtgctag gcaggtaaaa acggaaacct atactaatac
     3121 agtaacaaat gtccctattg acatacgcta taatagtgat aagtatttta ttagcggttt
     3181 tgcttcagaa gtatcagtgg tcttgactgg tgcaaatcgc ctatcgctag ctagtgaaat
     3241 gcaagaaagt acacgtaaat tcaaggttac tgctgaccta acagatgccg gtgttggaac
     3301 gattgaagtt cctttgagca ttgaagattt acccaatggg ctgaccgctg tggcgactcc
     3361 gcaaaaaatt acagtcaaga ttggtaagaa ggctcagaag gataaggtaa agattgtacc
     3421 agagattgac cctagtcaaa ttgatagtcg ggtacaaatt gaaaatgtca tggtgtcaga
     3481 taaagaagtg tctattacga gtgaccaaga gacattggat agaattgata agattatcgc
     3541 tgtcttgcca actagcgaac gcataacagg taattacagt ggttcagtac ctttgcaggc
     3601 aatcgaccgc aatggtgttg tcttaccggc agttatcact ccgtttgata caataatgaa
     3661 ggtgactaca aaaccagtag caccaagttc aagcacatca aattcaagta caagcagttc
     3721 atcggagaca tcttcgtcaa cgaaagcaac tagttcaaaa acgaattaaa aatagaaaag
     3781 gattttataa caatgggtaa atattttggg actgatggag tccgtggaga agctaaccta
     3841 gaactaacac cagaattagc ctttaaacta ggacgttttg gaggctatgt tcttagtcaa
     3901 catgaaacgg aagcgccgaa agtctttgta ggacgtgaca cacgtatttc aggggaaatg
     3961 ctggaatcgg ccttggtggc aggtctcctt tcagtaggga ttcacgtata caaacttggt
     4021 gtccttgcaa caccagcagt agcttacttg gttgaaactg aaggagcaag tgccggtgtc
     4081 atgatttctg ctagccacaa cccagccctt gataacggaa tcaagttctt tggcggtgat
     4141 ggcttcaaac tagatgatga aaaagaagca gaaattgaag ccttgctaga tgctgaggaa
     4201 gacactcttc ctcgtccaag tgcagaaggc ttaggaattt tggtagatta tccagaaggc
     4261 ttgcgtaagt atgaaggata ccttgtttca actggaactc ctcttgatgg aatgaaggtt
     4321 gccttggata cagctaatgg agcagcttct accagtgccc gtcaaatctt tgcagacctt
     4381 ggtgcccaat tgacggttat cggggaaaca ccagacggtc ttaacatcaa ccttaatgtt
     4441 ggttcaacac atccagaagc ccttcaagaa gtggtcaaag aaagtgggtc agctattggt
     4501 ttggcctttg atggagacag tgaccgcttg attgctgttg atgagaatgg tgacatcgtc
     4561 gatggtgaca agattatgta catcatcgga aaataccttt ctgaaaaagg acaattggct
     4621 caaaatacaa ttgtgacaac tgttatgtct aaccttggtt tccacaaggc cttgaatcgc
     4681 gaaggtatta acaaggcagt tactgcagtt ggtgaccgct acgttgttga agaaatgaga
     4741 aaatcaggct acaaccttgg tggtgaacag tctggtcacg ttatcttgat ggattacaat
     4801 accacaggtg atggtcaatt atcagcagtt caattgacta aaattatgaa ggaaactggt
     4861 aagagcttat cagagttggc ggcagaagta acgatttatc cacaaaaatt agttaatatc
     4921 cgagtggaaa acgtcatgaa ggaaaaggcc atggaagtgc cagctatcaa ggtcatcatc
     4981 gagaagatgg aagaagaaat ggcggggaac ggccgtatcc ttgttcgtcc aagtggaaca
     5041 gagcccctct tgcgtgttat ggcagaagcg cctacaacag aagaagtgga ctactatgtt
     5101 gatactatca cagatgtagt tcgtgctgaa attgggattg actaaatcct agaaaactag
     5161 atgaaaataa aaaattatgg tacaatagct tataatattg tagccgatgg agaaagacat
     5221 gaatcttaaa cgtgaacaag aatttgttag tcagtatcat tttgatgcgc gtaattttga
     5281 atgggaaaat gaaaatggag ctcctgaaac caaggtggat gtgaatttcc aattgctcca
     5341 acatgaccaa gaaaatcaag tgacttcctt gattgtcatc ttgagcttta tgattgtatt
     5401 tgataagttt gtcattagtg gaacaatctc acaagtaaac catatcgatg gccgtattgt
     5461 caatgaacca agtgaattga accaagaaga ggtggaaacc ttggctcgtc catgtttgaa
     5521 catgctcaat cgtttgactt acgaagtgac tgaaattgca ttagacttac caggaattaa
     5581 tttggagttc taatatgaaa ttagctgttt tcacagattc ctctgcttat ctcagtgaag
     5641 agaccttgca aagagaagac ttgtttgtct tggatattcc tgtcaatatt gatggtgagg
     5701 aatatgtcga aggcatcaat ctgtctgctg aggaatttta ccaaaaaatg gctcaggctt
     5761 ctgaattgcc taagaccagt caaccaagta ttgccaagtt agatgagatc ttaacttcgc
     5821 tcaaagaaca aggctataca catgccttgg ggcttttcct atcttctgga atttcaggtt
     5881 tttaccaaaa tatccagtat atggtcgatg actatgaggg cttaaccatt gctttcccag
     5941 acactttgat tacaagtgct cccctaggca tcatggttga aagcgtcttt aattggcgtg
     6001 atcagggcga tgattttgcc agcattcagg ataagctagc cattcaaatc agccgtacgt
     6061 cagcctttat catggtagat gacttggatc atttggtaaa aggtggacgc ctttcaaatg
     6121 gggctgccat tttgggcaat ttgcttagca ttaagccaat cctttatttt aacgatcaag
     6181 gtatgattga agtttacgaa aaagttcgta ctgaaaagaa ggccaccaag cgcttaattg
     6241 aaattatcaa ggaaacaacg gcttcaggtc aataccgggt cattgtcatt catgggaatg
     6301 ctcctgaaaa ggctgaagaa ttgcgtcagc atttgcttga ttttggcttg ggttcggatg
     6361 tttcacttgc tacatttggt agtgtcattg gaacgcacct aggatcagga agtattgctc
     6421 tgggttatat tccagtgatt tagttggcgc ttctaggcta gttaagatgc cttgtatctt
     6481 agaaattgaa cacggactac ctgcctcttg aaaaaagatg cctgtcttgc ctttcgtgga
     6541 aagtcagtgc cattccctat ttttcatggg tggctaagat cctttgtatc ttgataattg
     6601 aacacgcctg gaaccctgtg tgaaaaagat agttcttcca aggagtagac acttcttgat
     6661 cagaattcct attttcactt tgtgttctta caggctttgt atcttagaca ggagtagaga
     6721 tgagtattcg agtaattatt gccggtttta agggaaagat gggtcaagct gcttgccaga
     6781 tggtcttgac tgattcagat ttggacttgg tagcagtttt ggatcctttt gagtctgagt
     6841 cagaatggca gggtattcct gttttcaagg ataaggctga tttagctggt tttgaagcgg
     6901 atgtctgggt agactttact actccagctg ttgcctacga aaatacacgt tttgctcttg
     6961 aaaatggctt tgctccagta gttggaacga ctggtttcac gagtgaagaa attgcagagc
     7021 taaaagaatt ttctcgtgcc caagacttgg gtggtctgat tgcccctaac tttgccttgg
     7081 gtgctgtctt actcatgcaa tttgcgacgc aggctgccaa atatttccca aatgtggaga
     7141 ttattgaact ccatcatgac aagaaaaagg atgctccgag tggaacagcc attaaaacag
     7201 ctgagttgat ggcagaggtt cgagagtcaa ttcagcaagg tgcagcagat gaggaagagc
     7261 cgattgctgg tgctcgtggt gctgactttg atggtatgcg catccactca gttcgtttgc
     7321 caggcttggt agctcatcag gaagtcatct ttggcaatca gggagaaggg ttgaccctcc
     7381 gtcatgactc ctatgatcgc atctccttca tgacaggagt caatttggga attaaagaag
     7441 ttgtcaagcg tcatgagctt gtctatggat tagaacactt attatgagat taacgcaaat
     7501 gccttctgaa tttcagaagg ctttaccagt attagaaaaa attaaagaag caggctttga
     7561 ggcttatttt gttgggggct ctgttcgaga tgcccttctc catagcccta tccacgatgt
     7621 ggatattgcg acgtcttctt atccagaaga gaccaagcag atttttccgc gaacagccga
     7681 tatcggaatc gagcatggaa ccgtcttggt cttagatggg gatgaggagt atgaggtaac
     7741 aacctttcgg acagaggatg tctatgtgga ctatcgcaga cccagtgcgg tttcctttgt
     7801 gcgctcgcta gaagaagacc tcaaacgccg tgatttcaca gtcaacgcct ttgccttgga
     7861 tgagacagga gaaatcgttg acttgttcca tggtttagaa gatttggaaa agcaagtctt
     7921 gcgagcagtt ggagtggcta gtgagcgttt caacgaagat gctttacgga ttatgcgtgg
     7981 tttccgtttt caggctagtc ttggttttgc acttgagcca gaaacattta aagctatgaa
     8041 gaccttgacg ccgcttttgg agaaaatttc tgtagagcgt accttcgtcg agtttgataa
     8101 actcttgctg gctccatttt ggagaagggg cttggcttcc atgattgaga gtcaagctta
     8161 tgactatctc cctgatatgg catctagcca ggacaagctc aacagactgt ttgatttgga
     8221 gactgatttt acttttgaat cctctgaaca agcctgggcg gctttactat gggctttgga
     8281 gattgaaaat gcgcagtcat ttttgaaatc ttggaagacc tcacgccagt ttgccaagca
     8341 agttcaggat ttgctgatta ttttggctct gcgtgaaaat ggagaattga gcaagcgaga
     8401 ttgttatcgc tttgacatag atttgctttt acaggctgaa aatcttcgtc aagctcaagg
     8461 aaaagaagtc aacccacaag ccatcacaga aaaataccaa agcttgacta tccatgacaa
     8521 gaaagagatt cagattaatg gcgatatttt gatcaaggaa tatggctatc agccaggccc
     8581 agacttggga gagattttaa cagagattga gtttgccatt gtcgatggag aattggagaa
     8641 taatcgtgaa gccatccatg cttacctgag ggagaaaaaa tgagtgattt tatcgttgaa
     8701 aaactaagta aatccgttgg tgacaagacc gtttttaggg atatttcctt tattatccat
     8761 gacttagaca gaattggttt aatcggtgtc aatgggactg gcaagaccac ccttttggac
     8821 gtcctttctg gtgtttctgg atttgatggg gatgtcagtc ctttttcagc taaaaatgat
     8881 taccagattg gttacttgac tcaggatcct gattttgatg atagaaagac agttttggat
     8941 acggttctat ctagtgaact caaggaaatc cagctcattc gtgagtatga attgattatg
     9001 ctcgactata gtgaggacaa gcaggcgcgt ttggaacgtg tcatggcaga gatggactct
     9061 ctccaagctt gggaaatcga gagtcaggtc aagaccgttc ttagcaaatt gggcattcaa
     9121 gacttatcta ctcctgttgg ggaattgtca ggtggtctga gaagacgggt acagttggca
     9181 caagtcttac ttggcaacca cgacctcttg cttttggatg agccgaccaa ccatctggat
     9241 attgcgatta ttgagtggct gaccctcttt ttgaaaaatt ctaagaagac cgtccttttt
     9301 atcactcacg atcgttattt cttagacgct ttgtcaacac ggattttcga gttggatcgt
     9361 gcaggcttga ccgagtacca gggaaattac caggactatg ttcgcctaaa ggcggaacag
     9421 gatgagcgcg acgcggctct tcttcacaaa aaagaacaac tctacaaaca agaattggcc
     9481 tggatgcgca gacaaccgca ggcgcgtgcg accaagcagc aggcccgtat caatcgattc
     9541 catgatctga aaaaggaagt ttcaggcagt agtgctgaga cagacttgac catgaacttt
     9601 gaaaccagtc ggattgggaa gaaagtcatc gagtttcagg ctgtttcctt tgcctatgaa
     9661 aacaagccta ttttgcaaga ttttaatctc ttggtgcagg ccaaagaccg tatcggaatc
     9721 gttggggaca atggtgttgg aaaatcaacc ctgctcaact tgattgcagg aagtcttgag
     9781 ccaactaaag gacaagttgt gattggggaa actgttcgca tcgcctattt ctctcagcaa
     9841 attgagggtt tggatgaaag caagagagtt atcaattacc tgcaggaagt ggcagaagag
     9901 gtcaagacca gtggcggttc tacgacttcg attgcagagt tgctggagca gttccttttc
     9961 ccacgttcga cgcatggaac cttgattgag aaattgtcag ggggtgagaa aaaacgtctt
    10021 tatctcctca aactgctttt ggaaaaacca aatgttcttc ttttagacga gccaaccaat
    10081 gacctagata ttgcaacttt gacagtctta gagaatttct tgcaaggttt tgcaggtccc
    10141 gttttaacag tcagtcacga ccgctatttc ttggataagg tagcgaccaa gattctcgct
    10201 tttgaggatg gcaagattcg tcctttcttt ggtcattaca ccgactatct tgatgaaaaa
    10261 gcttttgaaa cagatatggc caatcaagtg caaaaggtcg aaaaggaaaa agtggtcaag
    10321 gttcgagaag acaagaaacg catgacctac caagaaaagc aggagtgggc aagtattgaa
    10381 ggtgatattg aaaccttgga aaaacgtatc gctgctattg aagaggaaat gcaggctaac
    10441 ggctctgact ttggtaagct ggctactctc caaaaagaat tggatgagaa aaatgaagca
    10501 ctccttgaaa aatacgaacg ctatgagtat ctcagtgaat ttgatagtta agactattcg
    10561 aaaatcaaag tgcaaactat gtcggcttca cattgccgac tcaagtacag cctgtgaccg
    10621 gcttcctaat ttgcactttg atttttattg agtataaacg aatagaaaaa tcccgtctca
    10681 tgaaaggatt tctctattct tttttggttt cttgatgaaa gatattttgc caggtttcgt
    10741 ggcgacgcca gatactggta tggatgatac catctaactc atagcagata agtttggttt
    10801 tttgactgat ggaagtaatt tgaatgtcct tgatagcaga atttaactct ttttttgtct
    10861 tataagcctc tttatccatc tgctctccat cttggcgaat atagacaaaa tcatcagtca
    10921 agagttcttc tagttggttt ccttggtcga tcaattgttc acgcataagc aattttttat
    10981 agacattgtc taaaatttca tcctcaggga taggtgctgg ttcgatatgg acatcggtat
    11041 caaagacgcc aaaacgattc tccagcatag actcgacctg atccgcgatt tcatggcttt
    11101 caaaaacaga caagtcagga ttcatctcta gtgtaatatc caggtagatg ttgctaccgt
    11161 aggtgcgacc tctttgcgat ttgaccttgc tgattttggg aatttccatg atagcctttt
    11221 ggtagtcctc gagcaggcgg tcgtcaaagc catctgaaag actaaaggaa gactcgatga
    11281 agatatcata ggcagtcttc aagataaaga aagtgatgat gatagcaacc agtttatcca
    11341 caatcggata attgaaacta ctagctagga tggcaatggc ggttccaagt gaggtaacag
    11401 cgtcagaaag attgtcctta gcagctgcct tcagcgcctt ggagttggat ttcttactga
    11461 ggcgagtatt gtagagatag accacaaaca taatcgctgc agaaatgatt cctagagttg
    11521 caccaagagg atcaatgacc gtttcttccc gactgagaat cttttgaatg gtatctctta
    11581 gaacatcgaa accgacatag aacatgatga tagaagtgat caagcttgcc aaatcttcaa
    11641 tcttccaatg accaaaacgg tggtcacggt ctgcaggctg gcgcgccatc cgaatcccga
    11701 ttaagagggc cacatttcca atgatgtccg atacgttatt aaaaccatcg gccaccaaac
    11761 tggatgaatg aaggagatga ccagctgcta atttggttgc agacaagatc aaataggtcg
    11821 aaatactgat aatggctcca cgctcagcta acttgagatt tgagatagat tgcttcattc
    11881 aacttccttt ctagtcacat agcattctac cattatactg gttttcaagg aaaaattcaa
    11941 ataaggcagt ttttactctt tgaaaactcc ccaaaatttg gtataatggt actactcaag
    12001 ggagtagctg gcagaaacct gtgatagtgt cgtcattccg aattttatgc tgaaaagtat
    12061 gctttccggc cctatcttaa acagcgagac ttgttatgat taacaggtct ctttttgttt
    12121 gtcgtgaaaa gatatgacag aaagagagtc tgttttgcac acaatgtcaa ggaggagaca
    12181 catgtcaaaa gaacaaaaac gccaagcgtt ttatactcag agccctgaag aggtcttgca
    12241 ggctgtggat gcgaccgagc aaggtttgtc atcaagtgag gcggaaaagc gccttgccga
    12301 atttgggcac aatgaactcg aagaaggcga gaaacgatca atcttggtca aattcatcga
    12361 gcaatttaag gatttgatga ttatcatcct agttgcggca gcaatcttgt cagtcgtgac
    12421 ttctggtggg gaagatatcg cagatgccat tatcatccta gctgtggtta tcatcaacgc
    12481 tgcctttggt gtttaccaag aaggaaaagc tgaagaagct attgaagccc tcaaatccat
    12541 gtctagtcca gttgcccgcg ttcttcgtga tggacacatg gcagagattg actctaaaga
    12601 attggtacca ggcgatatcg ttgcccttga agcaggtgat gtggtaccag cggacctacg
    12661 tttgatagaa gccaactctc ttaaaattga agaagcagcc ttgacaggtg aatctgtacc
    12721 agtcgaaaaa gacttgtcag tcgatcttgc gacagatgct ggcattggtg accgtgtcaa
    12781 catggccttc caaaactcaa acgtaaccta tggtcgtggg atgggtgttg ttgtcaatac
    12841 aggtatgtat actgaagttg gtcatattgc tggtatgctt caagatgcgg atgagactga
    12901 tacaccactc aaacaaaact tgaacaacct ttctaaggtc ttgacctatg ctatcttggt
    12961 cattgccctt gttacttttg tagtgggtgt cttcattcaa gggaaaaatc cacttggtga
    13021 gttgttgact tctgttgccc ttgccgttgc agccattcca gaaggacttc ctgctatcgt
    13081 taccatcgtt ctttctcttg gtactcaagt tttggccaaa cgacattcca tcgttcgtaa
    13141 gttgccagca gttgaaacac ttggttcaac tgaaatcatc gcttctgata agactggtac
    13201 gctaactatg aacaagatga cagtcgaaaa agtcttctac gatgcggttc tacatgactc
    13261 agctgatgat attgaactag gtcttgaaat gccactactt cgttcagttg tcttggccaa
    13321 tgatacgaaa atcgatgtgg aaggtaactt gattggtgac ccaaccgaaa cagcctttat
    13381 ccaatatgcc ttggacaagg gctatgatgt caaaggtttc ttagagaaat atcctcgtgt
    13441 agctgaattg ccatttgact ctgaccgtaa gctcatgtca acagttcacc cattgccaga
    13501 tggtcgtttc cttgtagcag tcaagggtgc gccagaccaa ctcttaaaac gttgtcttct
    13561 tcgtgataag gctggggata ttgctccgat tgatgagaag gttacaaatc tcattcatac
    13621 aaacaattct gaaatggctc atcaagcctt gcgtgtcctt gcaggtgctt ataagattat
    13681 cgatagtatt ccagaaaatc tcacttctga agagcttgaa aatgatttaa tttttactgg
    13741 tttgattggg atgattgacc ctgaacgtcc tgaagccgct gaggctgttc gtgtagctaa
    13801 ggaagcggga atccgtccaa ttatgattac aggtgaccac caagacacag cggaagccat
    13861 tgccaaacgt ttgggaatca ttgacgcaaa cgatacagaa ggtcacgttt taactggtgc
    13921 tgaactcaat gaactgtcag atgaagaatt tgaaaaagtc gttggtcaat actctgttta
    13981 tgcccgtgtg tctccagaac acaaggttcg tatcgtcaag gcttggcaaa aacaaggtaa
    14041 agtcgttgcc atgacaggtg acggtgtcaa tgacgcgcca gctctgaaaa cagccgatat
    14101 cggtatcggt atgggaatca ctggtacaga ggtttctaag ggggcttctg atatgattct
    14161 tgcagatgat aactttgcga ctattatcgt cgcagtggaa gaaggacgta aggtcttctc
    14221 aaacattcaa aagactattc agtacctact ttctgctaat actgctgaag tattaaccat
    14281 cttcctatca accttgtttg gttgggatgt cttgcagccg gttcatcttt tgtggatcaa
    14341 cttggtaacg gataccttcc cagctatcgc tcttggtgtt gaacctgcgg agcctggtgt
    14401 catgaatcat aaaccacgtg gacgcaaggc aagcttcttc tcaggtggtg ttttgagttc
    14461 tatcatttat caaggtgtac tccaagcagc tcttgttatg agtgtttatg gccttgcgat
    14521 tgcttaccca gttcatgtgg gtgacaatca tgctattcat gcagatgccc taacgatggc
    14581 ctttgcaacc cttggtttga ttcagctctt ccatgcctac aatgtcaagt ctgtctacca
    14641 atccatcttg acagttggcc cattcaagtc taagaccttt aactggtcca tcttggtatc
    14701 ctttatcctt ctcatggcaa caatcgttgt agaaccgctt gaaggaatct tccacgtaac
    14761 caaactagac ttgtcacaat ggggaattgt tatggctgga agcttctcaa tgattatcat
    14821 cgtcgaaatc gttaagttta ttcaacgcaa actcggtttt gacaagaatg cgatttaagg
    14881 gaggtttcgg atgtcagcat atcaattacc gaccgtatgg caggatgaag ctagtaatca
    14941 aggagctttt acggggctaa acagaccaac agcaggtgcc cgtttcgaac aaaacttgcc
    15001 aaaaggagaa caagcttttc agctttattc actgggaaca ccaaatggtg tgaaggttac
    15061 tatcttattg gaagaattac tagaagctgg ttttaaggaa gcggcttacg acttgtataa
    15121 gattgctatc atggatgggg atcaattcgg ctcagacttt gtgaagttca atccaaattc
    15181 caagattcca gccttattgg accagtcagg tactgaaaac gtaagagtct ttgagtctgc
    15241 tcatattctt ctttaccttg ctgagaaatt tggagccttt ttaccaagta atcctgtgga
    15301 aaaggtagaa gttttgaatt ggctattctg gcaagcaggt gcagcacctt ttctaggtgg
    15361 gggatttgga catttcttca attatgctac tgaaaaattg gaatatccta ttaaccgttt
    15421 tacgatggaa gtgaaacgcc agttggattt attggataag gaattggctc agaaacctta
    15481 tattgcaggc aatgactata cgattgcaga tattgctatc tggtcttggt atggacagtt
    15541 agttcaagga aatctttacc aaggttctgc aaaattcttg gatgcctcaa gttatcaaaa
    15601 tctagtaaaa tgggcagaaa aaattgccaa tcgtccagct gttaagcgtg gcttggaagt
    15661 aacttataca gaaattaaat agcaaaaaag tcatcttcgg atggcttttt gctacagttg
    15721 agggaaaggg tttgcagtta tcggcttttg tgctataatt gctataatat agtaaaaagc
    15781 aagaggagtg tgaggaagtg gaaaagaaaa ttgtgaagga tatcttattt ttatctcaag
    15841 tgtctcagcc ggcaagtcag gaggaccttt atcttgccag agatttgcag gatacactct
    15901 tagcaaatcg tgatacctgt gttggtctag ctgccaatat gattggggtg cagaagcgcg
    15961 tgattatctt taatcttggc ttggttcctg tggtcatgtt taacccagtg cttctgtcct
    16021 ttgaatgatc ctatgaggca gaagaaggct gtttgtcctt ggtaggtgtg agatcaacta
    16081 agcgttatga aaccataagg cttgcctatc gtgacagcaa gtggcaggaa cagaccatta
    16141 ccttgacagg cttcccagct cagatttgcc agcatgagct ggatcacttg gaaggacgaa
    16201 tcatttagga ggaaagcaaa tgaaacgaat agtctttgaa cttattttta tcgcaacgac
    16261 ctggtatatc tttttaccgc cccttaacct gaccagctgg gaatttctct tcttcctctg
    16321 tgggcatttg ttagttgtgg caatcttatt tggctttggc aaggggataa accttgtcaa
    16381 aacggttcat gtgcgccacg gtaaggcgga agctgcctta aatcttgagg gtttcaaaat
    16441 caatcggtta gggaaaattc tgttagcttc gattggagga attcttctct tggcagcttt
    16501 ggtttccttg gtaacttcta gcatgtttca ggctaaaaat tatgccaatg tagtcacggt
    16561 tacggaaaaa gactttactg aatttcctag gagtgacacc agtaaggttc ctatcctaga
    16621 tagaagtact gctgaaaaaa ttggagaccg ctacttgggt tccctaaccg ataaggtgtc
    16681 gcaatacgta gcggcagata cctataccca attgacaatt gatgggaaac cttatcgggt
    16741 cacaccacta gaatatgcag accctatcaa atggtttaac aatcaagcca agggaatcgg
    16801 tgagtatatc aaggtggaca tggtaactgg aaatgcggat ttggtggact tgaagacacc
    16861 aatcaagtat tcagactcgg agtattttaa ccgtgatgtc aaacgtcacc tgcgcttgaa
    16921 gtacccgacc aaaatcttta aaactccatc ttttgaggtg gacgatgagg gcaatccttt
    16981 ctatgtagca acggtttacc aaaagcaatt tggacttgct gttcctcgtc ctgcttcagt
    17041 cattatcttg gatgctacaa atggagaaac caaggaatac agcttatcag atgttccaga
    17101 atgggtggac aggatctatc cagcagagga aaccattgag caaatcaact acaacggcaa
    17161 gtacaaggac ggtttcttga atgccatgat ttccaagaaa aacgtgaccc agactaccaa
    17221 gggctataat tacttgtcta tcggtaatga catctatctc tacacaggtg tgacgtcggc
    17281 taatgcggat gagagtaatc ttggtttcat ccttgaaaat atgcgaacag gagaaatcac
    17341 taagtatagc ttggcttctg cgacagaaga atcagcccgt gaatcagcag aaggtgctgt
    17401 tcaggagaaa tcctacaaag caaccttccc aatcctcatc aacctcaatg acaagcctct
    17461 ctacatcatg ggcttgaagg acaatgctgg cttggtcaaa gagtacgccc tggtagacgc
    17521 agtcgagtac caaaatgtta tcgttgctac tacagtggaa gagatgctca gcaagtatgc
    17581 caataaaaac gaccttgaaa ttgacaatgc aacgacagaa agcatcaatg gagtagtagc
    17641 agacctcaaa tcagctgtta tcaagggaga cactgtctac ttctttaaag ttgatggcaa
    17701 gatatacaag gtcaaggctt cagtatccga tgaccttcct taccttgaaa atggtaaaac
    17761 cttcgaaggt caagtaggaa aagacaatta tctcaagacc tttaagctac ggtaaaaata
    17821 ggtttttttc agaaagtata tgttataata aggtaaatta agcctaatgg aggacaaaga
    17881 aatgggtttt tatttgatgg ttgcttcaat gctactcgga ctgctcgctt tgaagatagg
    17941 tttttctcag ttcaaggaga aaaaagataa attcttatct atcttaacaa gtttagctgg
    18001 cacagccctt gttctcgtgg ctgtctggtt aggatggccc aaataaatag aaaaacctcg
    18061 gtcaaaccga ggtttttcaa atgaatttct tggttgtggc taaaaaatat gctacactat
    18121 caatatgaaa attttaatcc caacagcaaa agaaatgaac acagacttgc caagtatcga
    18181 ggcaattcct ttaaaaccag aaagtcagac cgtgcttgat gccttggctc tctattctgc
    18241 cagtcaattg gagagtttct acaaggtatc agctgagaaa gcggcggaag aatttcaaaa
    18301 tatccaagct ttgaaaaggc aaactgctca acactatcca gccttgaaac tttttgatgg
    18361 gcttatgtac cgcaacatta agagagataa gctgaccgag gcggaacaag attatcttga
    18421 aaatcatgtc ttcattacct cggctttgta cggtgttgtt ccagccttgt cacccatggc
    18481 tcctcaccgt ttggattttt tgatgaaatt aaaagtcgct ggtaagactt tgaagagcca
    18541 ttggaaggca gtctatgatg aagctctgaa gaaggaagaa gtgattttct ctctcttgtc
    18601 atcagagttt gagactgtat tttctaagga aatcagagca aagatggtga ccttcaaatt
    18661 catggaggat agaggcggtc agctgaagat tcactcaact atctccaaga aagcgcgcgg
    18721 ggcctttcta acagctttaa tagaaaatca agtacaaact gtgggggaag cacgtcgctt
    18781 gaactttgct ggatttgttt accgagaaga tttgtcacaa ccacagggat tggtttttgt
    18841 aaaggaagta tagaaatcag atattttgta tttggcaata tgtatcatca gctgttttag
    18901 tttataaatg agaaaaaaag cgaacaagct agtcttctga gtgtcagaaa agtagtcttg
    18961 ttcgctttta ttatgttata ctcttcgaaa atctcttcaa gccatgtcag tgtcgcctta
    19021 ccgtatatat gttactgact tcgtcagttc tatctacaac ctcaaagcag tgctttgagt
    19081 agcttgcggc tagcttccta gtttgctttt tgatttttat tgagtgttag ttacttgata
    19141 gcttcgacca agtcttgagc ttgtttttca agtgagttta ggactgtttc ttcaagaacc
    19201 aattttccgt ctgcccaggc agagtcatta acacgtgcag cagtgaaatc accaacgcct
    19261 tgtgtacgga taaatggcaa gaggtctttg tagatagcga aaagttgatc gtgccctgca
    19321 ttggctacag atgatactgt gacaaacttg tcttgaaggg cagaaacgcc acgtgtatca
    19381 gacaagtcaa gggcacgaga tagccagtca agcaagtttt tcactgtacc agggatagag
    19441 aagttgtaga ctggagagaa aatccagata gcatccgcaa cgagaactgc ttcacgagca
    19501 gcagctacag ctggatgtgt tggaacttcc aaatcttggc taaagagagg aagggctgaa
    19561 taatcaaggt agctaacttc cgctttacca gcaagtgctt tctcagcttc gagcgccatt
    19621 tggtggttga aagaaccttg acgtagtgat ccgacgataa ataatacttt tttagacatg
    19681 atgtgtctcc tttttcttaa aatttcgaga attctctcgt tgttataaat tatattacaa
    19741 caaaacaaaa gaacttgcaa gaaatttgct cagagtttat ttgaaaattg taaaatttcg
    19801 gaaactctag tcatttgtga ctgaaaaagt aagaactgtt tcactttcaa aatcggtttt
    19861 gtttgaaggg agaaatagaa ttggttgctc aaagcacagc tttgaggttg cagataaagc
    19921 tgacgtggtt tgaagagatt ttcgaagagt attcttatat tcacttgtaa taaagcttaa
    19981 tagatggtaa aatagacgag tgaaaaaaag acaaaacaaa gcaaaaaata atctactgtg
    20041 gcagtatggt ctagggatga cgattttgtt tgtggttatc agtggttcct ttctgtatat
    20101 ggtttctctt agcatgaaac cctatcaaac agctaaaagt gaaggagaaa aattagctca
    20161 gcagtatgca ggattagagc aggctgttca ggttgattta tacaatggct tggaatctta
    20221 ttacagcgtt cttggtcgta ataaacagca agaagcgctt gctgtcctga ttggtaaaga
    20281 tgaccataag atttacgttt atcagctaaa tcagggtgtt tcacaagaaa aagcagaaac
    20341 ggtttctaag gaaaagggag ctggcgagat tgacaagata acctttggcc gttatcaaga
    20401 taagccaatc tgggaagtta agtcaggatc tgatttttat ctagtagatt ttgaaacagg
    20461 agcattggtc aacaaggagg gcctatgaaa ttatccaacc gtgttttaga aatggaagaa
    20521 agtgtgactt tggctgctgg agcccgtgcc aaagcactga aggctgaggg tagagatatt
    20581 ttgtctctaa ccttgggtga gccagatttc actactccca aaaatatcca agatgccgcc
    20641 attgcatcga ttcgagatgg gcgtgcttct ttttatacag taacctcagg tctgccagag
    20701 cttaaggcgg cggtcaatag ctactttgag cgcttttacg gctattctgt agcgtcaaat
    20761 caagtgacag tcgctgcggg agccaaatat tctctctata ccttctttat ggctgtggtc
    20821 aatccaggtg atgaagtcat catcccaacc ccatactggg ttagctatgg agatcaggtc
    20881 aagatggcag aaggcgttcc cgtctttgtt tctgctaagg aagacaatca ctttaaggtg
    20941 accgtggagc agttagaagc agctcggact gacaagacca aggttttggt gctgaattca
    21001 ccatctaatc cgacaggtat gatttacacc cgtgaggaac tcttggcaat cggaaactgg
    21061 gctgtagaaa aggatattct catcctagca gatgatatct atggccgctt ggtctataat
    21121 ggacatgaat ttacacccat ttctagccta tcggaagcga ttcgcaagca aacagtggtc
    21181 atcaatggtg tgtctaaaac ctatgccatg actggttggc ggattggcta tgccgtcgga
    21241 gaagcagaca ttatcgctgc catgtccaag attgcaggcc aaacaacctc gaacccttca
    21301 gcagtagccc agtatgcagc agttgaggct ctatcaggtg agcaagatac tgtagaaaac
    21361 atgcgtcagg cctttgaaga gcgactcaat accatctatc cccttcttgc tgaggtacca
    21421 ggatttgaag tggtcaaacc gcaaggagcc ttctatctct tcccaaatgt caaaaagggc
    21481 atggagatga aaggctatac ggatgtgaca gactttacaa ctgctatctt agaagaagcc
    21541 gaagtggcct tggtaacagg agcaggtttt ggagcgccag aaaatgtccg cctcagctat
    21601 gcgacagact tagacacgct taaagaagca gttaaacgct tgaaagtatt tatgggtagt
    21661 gagaatgatt gatcattttg agattaaggt aaaggattta caaatttcag aagattttta
    21721 taggagattt ctcgcccctt tgggctataa attggctttt aaaactactt ctctaatcag
    21781 ttttcttgcc ccaaatagcc ctcatcctgg tggtgatttt tggctggctc aggggacaca
    21841 agatcctatt cactttgctt tcttagcaga aaataaggaa gaagttcagg cttgttatga
    21901 ggctggttta gaggcaggtg ggcgagacaa tggggctcct gcttatcgca gtgagcaacc
    21961 gatttactac gctgctttta tgattgaccc agatgggaac aatatagaag tggtttgcca
    22021 taaagaataa aaaataaaaa ggaaaaacaa tgacaaaacg tgtaacgatt attgatgtaa
    22081 aagactatgt tggtcaggaa gtgacgattg gcgcttgggt tgccaacaaa tcaggaaaag
    22141 ggaaaattgc cttcttgcaa ttgcgcgatg gaacagcctt cttccaaggt gtggctttta
    22201 aaccaaactt tgtagaaaaa tttggtgaag aagtgggact tgagaagttt gatgttatca
    22261 aacgcttgag tcaagaaacg tctgtttatg tgacaggtat tgtcaaagag gacgaacgtt
    22321 ctaaatttgg ctatgagttg gacatcacag acatcgaagt gatcggtgaa tctcaagact
    22381 acccaatcac accaaaagaa cacggaacag acttcttgat ggacaaccgt cacttgtggc
    22441 ttcgttctcg taagcaagta gcggtgatgc agatccgtaa cgcaatcatt tatgcaactt
    22501 atgagttttt tgacaagaac ggcttcatga agtttgatag cccaatcctt tcaggaaacg
    22561 cggcagaaga ttcaactgaa ctctttgaaa cagactactt cggaacgcca gcctacttga
    22621 gccaatcagg tcagctttac ttggaagcag gagctatggc tcttggtcgt gtctttgact
    22681 ttggtccagt tttccgtgct gaaaaatcaa aaacgcgccg tcacttgact gagttctgga
    22741 tgatggacgc agagtactca tacttgacac atgatgagtc acttgatttg caggaagctt
    22801 atgtaaaagc tcttcttcaa ggtgttcttg atcgtgcgcc tcaagccttg gaaaccttgg
    22861 aacgtgatac agagctcttg aaacgctaca ttgcagagcc attcaaacgc atcacttatg
    22921 atcaagctat tgacctcttg caagagcatg aaaatgatga agatgctgac tacgaacatc
    22981 ttgagcatgg tgatgacttt ggttcaccac acgaaacgtg gatctcaaac cactttggtg
    23041 tgccaacatt tgtcatgaac tacccagcag ccatcaaggc cttctacatg aaaccagttc
    23101 ctggaaatct agagcgcgtg ctttgtgcag acttgcttgc tccagaaggc tatggagaaa
    23161 tcatcggtgg gtctatgcgt gaggaagact atgatgccct tgttgctaag atggatgaac
    23221 ttggtatgga ccgtacagag tacgaattct atcttgacct tcgtaaatac ggtacagttc
    23281 cacacggagg atttggtatc ggtatcgaac gtatggtaac cttcgctgca ggaacaaaac
    23341 acatccgtga agctattcca ttcccacgta tgttgcaccg tattaaacca taagaatagg
    23401 aaaacgccca tgtggcgttt tttcgaattc tagtgttttt acttgcgtaa aaaaattttt
    23461 tctagtataa taattcattg tgagcgaacc tcacttaccc cttgcaaagt cttggggtca
    23521 ttagaccaaa aggaggaaca tatcaatggc taaatacgaa attctttata tcattcgtcc
    23581 aaacattgaa gaagaagcta aaaacgcttt ggtagcacgt tttgactcta ttttgactga
    23641 caacggtgca actgttgttg aatcaaaaac ttgggaaaaa cgtcgtcttg catacgaaat
    23701 ccaagatttc cgtgaaggac tttaccacat cgttaacgtt gaagcaaatg acgatgcagc
    23761 tcttaaagag tttgaccgtc tttcaaaaat caacgctgac attcttcgtc acatgatcgt
    23821 caaaattgac gcgtaagaag gtaaactatg attaacaatg ttgtacttgt agggcgtatg
    23881 acacgtgacg ctgagttgcg ttatacccca tcaaatgtag cagttgcgac ttttactctt
    23941 gcagtaaacc gtacatttaa gagtcaaaat ggtgaacgtg aggctgattt tatcaatgtc
    24001 gttatgtggc gccaacaggc tgaaaatctt gctaactggg ctaaaaaagg ctcacttatc
    24061 ggggtgacag gtcgtatcca gactcgtagt tacgataacc agcaaggaca acgtgtctac
    24121 gtgacagagg tcgtggctga gaatttccaa atgttggaaa gccgtagtgt gcgtgagggt
    24181 cacacaggtg gagcttactc tgcaccaact gcaaactatt cagcacctac aaattcagta
    24241 ccagactttt cacgtaatga aaatccattt ggagcaacaa acccattgga tatttcagat
    24301 gatgatttac cattctaatg gacaactaaa cttataaagg agaaaaaaca tggctcaaca
    24361 acgtcgtggc ggattcaaac gccgtaaaaa agttgattac atcgcagcaa acaaaattga
    24421 atatgttgat tacaaagata ctgagcttct tagccgtttc gtttcagaac gtgggaaaat
    24481 ccttcctcgt cgtgtaacag gaacttcagc taaaaaccaa cgtaaagtaa caacagctat
    24541 caaacgcgct cgcgtaatgg ctttgatgcc tttcgtaaac gaagattaaa gaaaagaccc
    24601 ggttgggtct ctttttcatg agcttgaaaa caagaaagcg aattaagacc ccaacgggtc
    24661 ttttttcaca agctttgaaa tgagagagcg agttaggctc agtggctccc tttttacgag
    24721 tttgaaaaca agagaacaca ttaaaagcac atggagcttt ttcataaata tgtctctttt
    24781 ctcatccaag aaattaaaat aaaaatgata aactttttga aaatagggga tttgcctact
    24841 ttatgatata atggaaagag ttagattgaa agaggtagtg agatggacgc gaaattaaga
    24901 tacaaggcaa agaagatcaa gattgtcttt tttgatattg atgatacact gcggaattca
    24961 aagacagggt ttattccaac tacaattccc actgttttta aacagttgcg tgaaaaagga
    25021 attttaacag gaatcgcctc tggacgtggc atttttggtg ttgttccaga gattcgtgat
    25081 ctcaagcctg acttttttgt aactttgaat ggggcttata tcgaagataa aaaaggtcag
    25141 gtcatttatc agcatcagat tgaaaagtca gatgttgagg agtatatctc ttgggctaag
    25201 caagaaggaa ttgagtatgg cttggttggg agtcatgatg ccaagttgtc gactcgcacc
    25261 gatatgatga gtgaagctat caatccaatt tatcccgact tagatgtaga tcccgatttc
    25321 catgaaaaag aagatatcta tcagatgtgg acttttgaag ataagggaga tgacttgcac
    25381 ttgcctgata gtctctcaga caaacttcgc atggttcgtt ggcatcaaca ttcgtctgat
    25441 attgtgccga tttcaggctc caaagcgacg ggggtggaaa aggttgtgga acaccttggc
    25501 ttgaaaccag agaaggtcat ggtttttgga gatggtctca acgacttgga actctttgat
    25561 tatgctggaa tcagcgttgc catgggaatt tctcatgata aaatcaaaga aaaagcagat
    25621 tatattacaa aaacattaga agaagatggc atttttgatg ccttagaagt atttggtatg
    25681 gtagaaaaag aattgcattt tccacaagta gacattgaaa cagtagaagg tcctcttgcg
    25741 actattaaga ccaatcacgg agacttacgt atcaagcttt tccctgaaca tgctcctaaa
    25801 acagtggcta actttgtatc tctttcaaaa gatggctact atgatggtgt cattttccac
    25861 cgtattatca aggactttat gatccaaggt ggagacccaa ctggaactgg tatgggtggc
    25921 gagtcaatct acggcgaatc ttttgaggat gaattctcag aagagcttta caatatccgt
    25981 ggtgctcttt ccatggcaaa tgctggtcca aataccaacg gcagccagtt ctttatcgtg
    26041 caaaaccaac acctacctta ttctaagaaa gaaattactc gtggtggttg gccagaaccg
    26101 attgcagaaa tctatgccaa tcaaggtggg acacctcacc tagaccaccg tcacacggtt
    26161 tttggtcagt tagctgatga agcatcttac gctgtcttgg atgccattgc tgctgttgag
    26221 acaggagcta tggacaagcc agttgaagat gttgtaattg aaactattga aatcgaggac
    26281 taagatgaaa atcggtgata agctaaaggg gcgtattaca gggattcagc cctacggtgc
    26341 ctttgttgag ttagagacgg gtgatacggg gctgattcac atttcagaaa ttcggacagg
    26401 atttattgaa aatattcatg aaaccttgaa agtcgatgaa gaggttcaag ttcaggtagt
    26461 ggatttagat gaatttacgg ggaaagccag tctttctatc cgcactttgg aggaagaaaa
    26521 gtaccagttt cctagacgga gacgcttttc aagcgaccgc tttaactacg gttttgctcc
    26581 ctttcgacga atgctaccaa tctggactgg agaagccctg caccatttaa aaaagaagaa
    26641 gtagtttaga gttttatatt ttttgtaatg ttaatataaa tttgctataa taggaccatg
    26701 gaagaagaac aattattaaa atcaggagag cgcattaacc agctcttttc gacagatatc
    26761 aaaatcattc aaaatagaga ggtttttagc tattcggtgg atagtgttct cttatcacga
    26821 tttccacgtt ttcctaagaa ggggttgatt gtggatttct gtgctgggaa tggagcagtg
    26881 gggctttttg ctagcactcg tactcaagca cagatattgt ctgttgagat tcaggagcgt
    26941 ttggcggata tggctgaacg ctctgtccga ttgaatggat tagaggagca aatgcaggtc
    27001 atctgcgatg atttgaaaaa tatgcctgct cacattcagg ggagtaaggt ggatatgatt
    27061 ttgtgtaatc caccctattt caaggtggat ccttattcta atctgaacga gagtgaacat
    27121 tatctcttgg ctcgacacga aatcacgact aatttggaag aaatctgtcg tagtgcccag
    27181 agtattctca agtctaatgg gcgtttggcc atggttcatc gtcctgatcg acttctggat
    27241 attttggata cgttaaaacg acataatcta gcccctaagc gcctgcagtt tgtttatcca
    27301 aaaagagaaa aggaagccaa tatgcttttg attgaggcga tcaaggatgg ctcaacaagt
    27361 ggctttaagg tcttacctcc tttgattgtc cacaatgatg atggctctta tacgcccgaa
    27421 atcgaagaga tttattatgg atcataaggc ttatatgtac gttctggagt gtcgtgatgg
    27481 atcctactat ataggctata cgactgatgt gagaagacgc ctcgctatcc acaatagtgg
    27541 gaagggagcc aaatatacac gagcacgctt gccagtcaaa cttatctatg ctcaaggttt
    27601 tgccagtaag gaagaagcca tgtcggctga agctcttctc aagcgtaaga agaggccaca
    27661 gaaggaagaa tttttatccg aaaatcaaga tagaaattta ctcagttatt ttgaagaatc
    27721 gtggggagtc ctttgactcc tcttaccttt gtcaaaaagc gaaaaaaatg ctacaataaa
    27781 gaaaataaac aaaatgaggt attatcatgt ccaagattct agtatttggt caccaaaatc
    27841 cagactcaga tgccatcgga tcatctgtag cttttgccta ccttgcaaaa gaagcttacg
    27901 gtttggatac ggaagctgtt gcccttggaa ctccaaatga agaaacagcc tttgtcttga
    27961 actattttgg tgtggaagca ccacgtgtta tcacttctgc caaagcagag ggggcagagc
    28021 aagttatctt gactgaccac aatgaattcc aacaatctgt atcagatatc gctgaagtag
    28081 aagtttacgg tgttgtagac caccaccgtg tggctaactt tgaaactgca agcccacttt
    28141 acatgcgttt ggagccagtt ggatcagcgt cttcaatcgt ttaccgtatg ttcaaagaac
    28201 atggtgtagc tgtgcctaaa gagattgcag gtttgatgct ttcaggtttg atttcagata
    28261 cccttctttt gaaatcacca acaacacacc caacagataa aatcattgct cctgaattgg
    28321 ctgaattggc tggtgtgaac ttggaagaat atggtttggc aatgttgaaa gctggtacca
    28381 acttggctag caaatctgct gaagaattga ttgatatcga tgctaagact tttgaactca
    28441 acggaaataa tgtccgtgtt gcccaagtga acacagttga catcgctgaa gttttggaac
    28501 gccaagcaga aattgaagct gcaatgcaag ctgccaacga atcaaacggc tactctgact
    28561 ttgtcttgat gattacagat atcgtcaact caaactcaga aatcttggct cttggtgcca
    28621 atatggacaa ggtcgaagcg gctttcaact tcaaacttga aaacaatcat gccttccttg
    28681 ctggtgccgt ttcacgtaag aaacaagtgg tacctcaatt gactgaaagc tttaatgcgt
    28741 aagattttgg gtgtcagctc aaaatcggaa agtctagttt gccttatatc gaaaggagtt
    28801 tcggctcctt ttttctagga gtgaagtatg ttagaaaatg gcgatgtgat ttttgtgaga
    28861 gatgggtcag acatgggaca ggccatccag acttccacag gtaactatag ccatgttgcc
    28921 atttatttgg atgggatgat ttatcatgct agtggacagg ctggtgttgt ctgtcaagaa
    28981 ccggcagact tctttgagtc caatcattta tacgacctct atgtttaccc agaaatggat
    29041 atccagtcgg tgaaggaaag agcttgcaaa catcttggag caccctacaa tgcttctttc
    29101 tatccagatg cagctggttt ctactgctcc cagtatatag cagaaatcct acctattttt
    29161 gaaactattc ctatgaaatt tggagatggg gaacaggaga ttagtgattt ttggagggag
    29221 tattacatag aactaggtct gcctgttcct ctgaaccaag ctgggaccaa tcctagtcag
    29281 ttggcagcat cgcctctgtt acaatgtaaa gaaaggaatc ttcatgattc agatttttaa
    29341 tccatctcgt ttgacgagac agccattttt ggagaattga tccgctatct ggatcagtat
    29401 gaggatgtga ttctacggga aattaaggct caatttccag atgttgcagt tgataaactc
    29461 atggaagagt atataaaggc aggcttgatt ctacgtgaaa ataagcgcta ttacctcaat
    29521 tttcctacgc ttgaatcact tgatagtctt gaactggatc aagagatttt tgtcagagaa
    29581 gctagtccgg tctatcaagc cttgttggag cagagttttg agacggaatt gcgcaattaa
    29641 atcaatgcag ctattttagt tgaaaagacg gactttgcgc gcattaaaat gaccctgtcc
    29701 aattattttt acaaggtcaa acagcagtat cctttgacag aaaaacagca ggagctctat
    29761 gacattttag gagatgttaa tcctgagtat gccctcaagt atatgacggc ttttttgttg
    29821 aaatttctca aaaaagacca gcttatgcag aaatgccgtg atatctttgt ggacagttag
    29881 gttgtcttag gctatattgt gcaaaatgaa gatggaaagt atgagttggc tatcgatttt
    29941 gataaggaga ggttaacttt ctacttagcg tgatttcttg tttctgagta cattgtttga
    30001 ctttccttag tattcggtat aaactatatg taaccggtaa cacatatcgg aataaactaa
    30061 aggagacaat catatgtcac ttgaaaacaa attggaacaa gcaacaggcg ctgtcaaaga
    30121 aggttttggt aaagttactg gagacagcaa gacagaactt gaaggagctg ttgaaaaaac
    30181 agtttctaag gcaaaagacg ttgtagaaga cgcaaaaggt gctgtagaag gtgccgttga
    30241 aggtttgaaa aacgttttta ctaaataata ggaaaaaatc aagggtttca ttttcccttg
    30301 attttttcta ttcttataaa taattttctg cgacggctgt atctcctggg taggattctt
    30361 tcttgccctg gatgatttgg taacaatcgg ctcccttacc cgcaataata actgcatcta
    30421 attcgtgatt tgtgatagcc attgccgcct tgatggcttc ttggcgatcc gcaatctttt
    30481 caacaggatg attgatgtag ctactaattt catctgcaat ggccattggg tcttcatagt
    30541 tagggtcatc agcagtcaga aagacttgaa tctcagggtg ttgattgagg aggaggccaa
    30601 agtccttacg acgactttct cccttgtttc ctgttgttcc cagaaccaga gcaatctttc
    30661 cggtttgatg agtttcaacc acattgatga gttttttcag actatcccca ttgtgggcat
    30721 agtcgatgaa gaccttggct ccatttttct gagtgaggac ttccatacga ccaggaacgc
    30781 gggttgcagc gatgcctttt ttgatgtcct caagacttgc tccgagacgg agacaagcaa
    30841 gtccagcagc aactgcattt tcttggttga agttgccaat gagttggata tcataatctc
    30901 cagcgagttt acccgtagct gaaaagctaa aggctttgga attctcgatt tggttatcaa
    30961 attggctacc atagaaatca tggtcttgat cttcaacctg ttctttcaag actgagaagt
    31021 ggtccatgtc actgttaatg atgactgctc ggctattttc catcaagaga cgcttgtggt
    31081 agaaatagtc ttcaaagcta gggtgttcaa tcgggccgat atggtcagga gtgatgttaa
    31141 gaaagactcc tacatcaaag gtcagtccat agactcgatg gactagatag gcttgactgg
    31201 agacttccat gatgaggtgg gtacggtcat tttgcacagc ctgattcatc atgtcaaaga
    31261 ggtcaatact ctcaggggtt gtcaacgctg acttaaagaa agtctcgcca tcaagagttg
    31321 tgttcatggt cgacaacata gcaggtctat gcccttgaga taagatgtta taggcgaaat
    31381 aggttgctgt tgtcttaccc ttagtaccag taaaggcaag gagtttgagt ttctcttgtg
    31441 gattaccata gaactccatg gcaatcaaac tcatggcttt ctttatatcg ttcacaatga
    31501 tgacagggat accgacttcg tagtcctttt cagctacata ccaagctaaa ccttgtgtta
    31561 tagcagaaag aaggtattct tttttaaagg cagcgccttt tgcaaaaaaa agagtgtctt
    31621 ctgttacttt tcggctgtcg tagctgatgc tatcaaaaat aactttgctg tagttgtagt
    31681 ggtaatgacc ttggtcaata atttcgcgaa aaaggccatc tttctttaaa atatctaata
    31741 cggtttcaat cttaatcata ctttctattg taaaccgaaa gtcgtaaatt tacaagtaac
    31801 aaggaaaagt ttataatgga agataaggag tttttcctag ttatcaaaat tgaatgagga
    31861 atctatgtcg cacgaaaaca atcaccagca ggcccagatg ttacggggga ctgcttggct
    31921 aacggctagt aactttatca gtcgcctact cggggctgtt tacattatcc cttggtacat
    31981 ctggatgggg gcttatgcag ctaaggcaaa tggtctcttt accatgggtt acaatatcta
    32041 tgcttggttc ttgttggttt caacagcggg gattccagtt gcggtggcca agcaagttgc
    32101 caagtataat accatgcgag aagaagagca tagctttgcc ctgattcgga gcttcttagg
    32161 ctttatgaca ggactaggcc tggtttttgc tttagtcttg tatgtctttg ctccttggct
    32221 agcagacttg tctggcgtgg gcaaagactt gatcccaatc atgcaaagct tggcttgggg
    32281 agtcttgatt ttcccgtcta tgagtgttat ccgaggattt ttccaaggga tgaataacct
    32341 caaaccctat gccatgagcc aaattgctga gcaggtcatt cgtgttatct ggatgctcct
    32401 agcaaccttt atcattatga agctcggttc aggagattat ctagcagccg ttacccaatc
    32461 aacctttgct gcctttgtcg gtatggtagc cagttttgca gtcttaattt atttccttgc
    32521 ccaagaaggt tcactcaaaa gagtctttga aacaggagat aagattaaca gtaagcgtct
    32581 cttggttgat accattaagg aagccattcc ttttatcctg acagggtctg ccatccagct
    32641 cttccagatt ttggatcagc tgacctttat caatagtatg agctggttta ccaactacag
    32701 caatgaggac ttggttgtca tgttttctta tttctcagcc aatcctaata aaatcacgat
    32761 gattttgatt tctgtagggg tttcgattgg gagtgttggt ttgccacttt tgacggaaaa
    32821 ctatgtcaag ggggacttga aagcagcttc tcgtctggtt caggacagtc tcaccctact
    32881 ctttatgttc ttgctaccag caacggttgg agtggttatg gtaggagaac ctctttatac
    32941 ggtcttctat ggtaagccag atagtttggc tatgggctta tttgtctttg cagttttgca
    33001 gtctattatt ttaggtttgt acatggtctt gtctccaatg cttcaggcca tgttccgcaa
    33061 ccgcaaggcc gttctctatt ttatctatgg ttctattgcc aagctagtct tgcaactacc
    33121 taccatcgcc ctcttccaca gttatggtcc tttgatttca acaaccattg ctctcatcat
    33181 tcctaacgtc ttgatgtatc gggatatttg taaagtaact ggtgtcaagc gcaaggtgat
    33241 tttgaagcga accattttaa tcagtttgct gaccctagtc atgtttctgt taataggaac
    33301 catccagtgg ctgttaggat ttttcttcca accaagtgga cgtttgtgga gcttctttta
    33361 tgtagctctt gtcggtgcca tggggggtgg actttatatg gttatgagtc tgcgtaccta
    33421 tttattagat aaggtaatag gaaaagtcca agcagatcgc ctgcgagcaa aatttaagct
    33481 ttcgtaaggt ggcatttata aataaaagga ataagttgaa caatctttta ggagaacttg
    33541 aaacttattc ctttttttag cgtcaaaata gctaaaatta tctttcaaaa atagaaaatg
    33601 aggttttttt cgattttttg gaaaaaacaa ttgactaaac aaacaaagag ttgtataata
    33661 aaacaaatat ttaaagcagg aggttctgga aatgaaaaag tctaagagca aatatctaac
    33721 cttggcaggt cttgtcctgg gtacaggagt tttattgagc gcgtgtggaa attctagcac
    33781 tgcatcaaaa acctataact atgtttattc aagtgatcca tctagtttga actatctagc
    33841 agaaaaccgc gcaacaacca atgatattgt gaccaatctg gtagatggtc tcatggaaaa
    33901 tgaccaatat gggaactatg tgccatcctt ggcagaagat tggactgttt ctcaggatgg
    33961 tttgacctat acctacaaac ttcgtaagga tgccaagtgg tttacttctg agggagaaga
    34021 atatgcacct gtaactgccc aggattttgt gacaggattg caatatgcag ctgataaaaa
    34081 atcagaagcc ttgtatctag tgcaggactc tgttgcaggt ttggatgact atatcactgg
    34141 taaaacaagc gacttttcaa ctgtcggtat caaggctctt gatgatcaaa ccgttcaata
    34201 caccttggct cgaccagaac cttactggaa ctcaaaaaca acctcaacca ttcttttccc
    34261 agtcaatgca gatttcttga aatcaaaagg ggatgatttt ggcaaggtag accctgctaa
    34321 tattttgtac agtggacctt tcttgatgaa agcttttgtt tcaaaatctg tcatcgaata
    34381 caagaaaaat cctaactact gggatgctaa aaatgtcttt gtagacgatg tgaaattgac
    34441 ctactatgat ggtagcgacc aagaatcact ggaacgtaat tttacagctg gtgcttatac
    34501 tacggctcgt ctttttccta acagctccag ctatgaaggg attaaagaaa aatacaaaaa
    34561 caatatcatc tatagtatgc aaaattcaac ttcatatttc tttaatttta acctagatag
    34621 gaagtcttac aattatactt ctaaaacaag tgacattgaa aagaaatcga ctcaggaagc
    34681 agttctcaat aaaaatttcc gtcaggctat caattttgct tttgacagaa catcttatgg
    34741 ggctcagtct gaagggaaag aaggtgcaac aaagattttg cgtaacctag tggttcctcc
    34801 aaactttgtc agtatcaagg gaaaagactt tggtgaagtt gtagcctcta agatggtcaa
    34861 ctatggtaag gaatggcaag gtatcaactt tgcggatggt caagaccctt actacaatcc
    34921 tgagaaagcc aaggctaagt ttgcggaagc taagaaagaa ctcgaagcaa agggtgttca
    34981 attcccaatc cacttggata agactgtgga agtaacagat aaagtaggca tacaaggagt
    35041 tagttctatc aaacaatcaa ttgaatctgt tttaggttct gataatgtag tgattgacat
    35101 tcagcaatta acatcagatg agtttgacag ttcaggctac tttgctcaaa cagctgctca
    35161 gaaagactat gatttatatc atggcggttg gggacctgat tatcaagacc cgtcaaccta
    35221 tctcgatatt tttaatacta atagtggagg agttctacaa aatcttggac tagagcctgg
    35281 agaagccaat gacaaggcta aggcagttgg actggatgtc tatactaaaa tgttggaaga
    35341 agctaataaa gagcaagatc cagccaaacg ttatgagaaa tatgctgata ttcaagcttg
    35401 gttgattgat agttctttag ttcttccaag tgtttcgcgt gggggaacac catcattgag
    35461 aagaaccgta ccatttgctg ctgcctatgg tttaaccggt acaaaagggg ttgaatcata
    35521 taaatacctc aaagtacaag ataagattgt cacaacagac gaatatgcaa aagccagaga
    35581 aaaatggttg aaagaaaaag aagaatccaa taaaaaagcc caagaagaat tggcaaaaca
    35641 tgtcaaataa aatctaattg tagataagtt tgtgtaagaa gtctttgtgc ttaaaaacgc
    35701 ataatatcag gtatataaaa tcctagatgt tatgcgtttt gttataggaa gatttattag
    35761 attttatcct caaattgagt tattcccgac tttatccgtt gaaatattat aaggagtatt
    35821 tatgaaatta aaattattaa gagtagatac taaggtgatt atggggagtt tcttacttgt
    35881 tctgtctagt ctacttgctt tgttgcttcc ccttatctta aagggtttaa tagatgggag
    35941 ttctattgaa aatataggtt ccaaagtatt tcaatcgttt ttgattttta ttggtcaagc
    36001 cttgttttct tctattggtt actatctgtt tagtcaatcg ggtgaaaaaa agatagcaaa
    36061 aatcaggaaa aaagtgacag aggggttgat ttatgcagag aaatccttct ttgataagag
    36121 ccaaagtggg gagttgactt ctgccattgt caatgacacg agtgtcattc gtgagttttt
    36181 aattacgact ttcccaaata ttattctgag tttagttatg gtacttggtt ccattgtagt
    36241 cttatttagt cttgattgga atctttctct acttttattc atcactcttc cttgtatgat
    36301 gtttattatc ttgccccttt ccaatatcag tgaaaagtat agtcgtcgtt tacaggagga
    36361 aatcggattt ttaacagggc aattgactga aaagattcaa gaacatgaat taattaagac
    36421 taaccaagca gagaaaagtg tacaggatgt tttggataat tgtattgaaa gggtacaaaa
    36481 caattcactg aaatcagata gggttacttc ttttgagacc ccgtttgctc tcttatttat
    36541 ctttgcgact atagctgtga tgctaaccta tgggggttat cgggtcagcg caggatatat
    36601 atctgtggga accttggttt cgtttttgat ttacctcttt caattactta atcctattag
    36661 taatatagct aattttgtaa ctgtttattc taggagcaag ggatcttcag ttgcactgga
    36721 gaacttgctt gcagttccta aagaaaaatt tgagggagga aaatcggtat caggacaagg
    36781 gttgaatttt aaccatgtct attttggtta tgatgaaaat cgacctgtct taaaggatat
    36841 tacttgttca attttcaagg ggcaaaaaat tgcttttgtt ggaccatctg gatcaggaaa
    36901 atcaacgatt gtgcgtttgt tagagcagtt ttataaaccg ctttcaggag atattctaat
    36961 ggagcaatca agtatatatg attttaactt aaaagaatgg agaagtaaaa tcgcttgggt
    37021 ttcacaaaat aatgcagtct tatctggcag tattcgtgac aatctttgtc tcggtttgaa
    37081 tcgcttagta actgatgatg aattgatgaa agtgctagac ttagtatcac taggtgatga
    37141 gattcgctcc atgaaagagg gactagatac tgaagttggt gaacgcggac gactcttgtc
    37201 aggggggcga agccaaagac ttcaaatagc tagagcctac ttaaaagatg ctgaaattct
    37261 tatatttgat gaagccactg ctaatcttga tgcggattct gagtatgcga ttatcagtag
    37321 cctctattct gtactaaagg agaagacggt tgtgattata gcgcatcgtt tgtcaacggt
    37381 aaaagatgtg gattgtattt tcttcttaga ggaggggaaa atcactggct caggaactca
    37441 taaggaacta ctggaaaatc atgagcgtta tgctcgtttt gtgcaggagc aaatgataga
    37501 gtgaaggtgt cttttgagat tcaccatttt atagtctatt aaagggagca ggaaaaactc
    37561 cctttttata tagtttgaaa ctataactag ctcttgaaaa gaagaaaatg agttgatgaa
    37621 aataagtggt acaatagtta ctatagattt ggaggaattg tatgagcaag gaattacaca
    37681 ttaacacaat tttagcacaa gcagggatca agtctgatga ggcaacaggt gctttggtga
    37741 caccacttca tttttcaacg acctatcagc atccagagtt tggtcgatct actgggtttg
    37801 actatacgcg cactaaaaat ccaactcgta gtaaggctga ggaagtcttg gcgactattg
    37861 agtcagcaga ctatgcctta gcgactagct cagggatgtc agctattgta ctggccttta
    37921 gcggctttcc agtaggaagt aaggtcttgg cagtgcgtga tctttacggc ggttcttttc
    37981 gctggtttaa ccaagtggag caggaaggtc gtttccattt tacctatgcc aatacagaag
    38041 aagagttgat tgccgagtta gaaaaggatg tggatgttct ctatatcgaa accccaacca
    38101 atcccttgat gttggaattt gatatcgaaa aactagcaaa attggctcat gctaagggtg
    38161 ccaaagtggt ggtggacaat accttctata gccctatcta ccaacgtccg attgaagatg
    38221 gagcagatat cgttctccat tcagcaacca agtatctagc aggccacaat gatgtcttgg
    38281 ctggagtggt tgtgaccaat agtttagaac tatacgagaa gcttttttac aatctcaata
    38341 caacaggggc agtcttgtct ccatttgaca gctaccagtt gcttcgtggt ctcaagacct
    38401 tgtctcttcg tatggagcgc tcaacagcta acgcccaaga agtggttgcc tttttgaagg
    38461 attctccagc agttaaggaa gttctctaca ctggtcgtgg aggcatgatt tcctttaaag
    38521 tagccgatga aacacgcatt cctcatattt tgaacagtct caaggtcttc tcttttgcgg
    38581 aaagtttggg cggagtggaa agtcttatta cttatccaac gactcaaact catgctgata
    38641 ttccagcaga agtacgccat tcttatggtt tgacagatga cctcttgcgt ttgtctattg
    38701 ggattgagga tgctagagat ttgattgcag atttgcgcca agccttagaa ggataagaca
    38761 aagatgggaa aatatgattt tacaagcctg cccaaccgtt tagggcacca tacctataaa
    38821 tggaaagaaa cagaaacgga tagtgaagtt ctaccagctt ggatagcgga tatggacttt
    38881 gtggtcttgc ctgaaatccg ccaagccgtg caaacttacg cagaccaact ggtttatggt
    38941 tatacctatg ccagtgaaga cttaattaag gaagttcaaa agtgggaagc tacacaatac
    39001 ggttacaact ttgacaaaga ggctcttgtc tttatcgagg gtgtggtacc agccatctca
    39061 acagctattc aaacctttac aaaagaaggc gaggcggttt taattaacac gcctgtctac
    39121 ccaccctttg ctcgcagtgt caagttgaat aatcgtagat tgattactaa ttccttagtg
    39181 gaaaaggatg gtctgcttga gattgacttt gaccaacttg aaaaggattt ggtggaagag
    39241 gaggttaaac tctatattct ttgcaaccct cacaatcctg gtggacgtgt ttgggaaaaa
    39301 gaagtgttgg agaagattgg ccaactctgc caaaaacacg gtgttttgtt agtttcggat
    39361 gagattcacc aagatttgac cctctttggt cacaaacacc agtctttcaa taccatcaat
    39421 cctgccttca aaaattttgc tatcgtcttg agcagtgcca ctaaaacatt taatattgct
    39481 ggaacaaaaa attcctatgc agtcattgaa aatcctaagt tgagactagc tttccagaaa
    39541 cgcctgttgg ccaataatca gcatgaaatt tcaggcttgg gttatttggc gacagaagct
    39601 gcctatcgat acggtaaaga ttggctagag gaactcaagc aagtctttga agaccacatc
    39661 aattatgtgg tggatctatt tggaaaagag actaaaatca aggtcatgaa accgcaaggt
    39721 acctacttga tttggcttga cttttcagct tatgacctga ctgatgaaac attgcaagag
    39781 ttgttgagaa atgaagccaa ggttatcctc aaccgtggtt tggattttgg agaggaagga
    39841 agtctccatg cccgcatcaa tatagctatg cccaaatctc tgttgcaaga agtctgtcag
    39901 cggattgtgg ctacttttgc caaacgttaa aaatccagcc ttctaggaga aaagtcttcc
    39961 tagaaggcta ttttcatagg cgaaaatatg gtataataaa aagataaggt aaaggtgaaa
    40021 atatggctaa attgattccg gggaaaattc gtatcgaagg tgttgccctt tatgaaactg
    40081 gtaaggttga tatcatcaag gaaaagaaca atcggctcta cgctcgcgtt gcagaagaag
    40141 aactacgcta tagtttagag gatgatttgg ttttttgtgc ctgtgatttt tttcaaaaga
    40201 ggggttactg tgtgcatttg gcagcgctag agcattttct gaaaaatgat gagcgtggtc
    40261 aggaaatctt gtggagtctg gaagaaggtc atgaagaaaa agaggctgtt gaaaccaagg
    40321 tgaccttggg tggcaagttt ttggatcgaa ttttatctcc aaaatcagaa tgcgcctatg
    40381 agttatcagc tgtgggtcag gtggaagcag gaaccaatca tatcttgtgg actctgagaa
    40441 tcggccaaat caatagccaa aaatactatg tcattcggga tattccactt tttttaagga
    40501 ttgtcgagca gagaaagtcg tatatgattg gcaagattta tgaggagtct ctttcttggg
    40561 aagcctttga tgatgccagc caagaacttt tgactttctt gcacggacta acggaggaag
    40621 ggctggtttc agacctcttt ttccaaaacc aaggtcggca cctctttttc cctctgacct
    40681 tttttgagca gggtgtgaat ttactgatgg ccttgcccca ttttcaattt gaccatcaag
    40741 tggatagcta ccaaaccctg ctttttcagg atatgcatgc tgatgccaat ctatttgcct
    40801 ttacagtaac agaatactcg gactattttg aaatggaaat cagtgagagt cctagggtca
    40861 atgtctttta tcagggagca gtacttttcc ataaaggtca ggtttatttt ttaacagacc
    40921 agcagatgcg tcttctcaag gaaattaaag tgttacctgt gggtcaacaa ggaaagaaat
    40981 acctgcaatt tgatagcagt gatcgagaca aattggcctc ctgtctgact ctttttatcc
    41041 agatgggcac cgtttcagct ccagaacgtc tacaaatcaa aacttttgcg ccctcttttt
    41101 actttgacag ggaagaagat aatcggattc gtttagaaat tcagtttgat tatggaaata
    41161 gacaggtatc tagccgacaa gagctagaag aattaccatt ttcaagtgac gcggacttag
    41221 aagaaagaat tttccaagtc tgtttggctg cgggctttga agccgatttt caatcttggc
    41281 gtcaggcctt aaaagcggag tctgtctatc atttttttca tgatatcatt ccagtctttg
    41341 aaaaactcgg gcatgttgac ctatcagata aactagaaga gctttatagc ctagcgagtc
    41401 ctcaggtgca gattgcctcc aagggaggtc tcttggaaat ccagtttgat tttcaaaata
    41461 ttgcccagga ggaaatcgac caagccatgc aggccttggt tgccaatcag gatttttata
    41521 ttgattcgtc taatcaagtt tactttttcg atgaagaaac caagaaaatt cgccaaaatc
    41581 tacaggaact ggggcaattt gaattaaaag atgggacctt gcaggctcgg aaatccttgg
    41641 cctacagttt agctcatcta tttgaagggc gagaccgtgt ttctttttca caagaattcc
    41701 agaatctggc ccaggatttg acgcatccag aggactttcc tttgcaagca actcaggtca
    41761 aggctgactt gcgagattat caggaaaagg gaattggctg gttgcagatg ctccatcatt
    41821 atggttttgg tgggattttg gctgatgata tgggacttgg gaaaaccctt cagaccattg
    41881 cttttttgac tagtcaagtg acaaaagaaa gtcgagtctt gattctcgct ccgtcgggtt
    41941 tgatttacaa ctgggcggat gagtttcaga aatttgcccc acagttggat gtggctgttg
    42001 ttcatggttt gaaagcaagt cgtgaggaga ttcttgccga tagccatcaa atctatgtga
    42061 ctagctatgc catcttccgt caggacagtg agctttatca ggggatggcc tttgacttcc
    42121 ttttcttaga tgaagctcag gtcatgaaaa atgcccagac caagattgcc cagaccttga
    42181 gacaatttgt ggtgccgtcg gtctttgcct tgtcaggaac tccgattgaa aaccatctgg
    42241 gtgagttgtg gtctattttc caaatcgtca tgcccggact tttgccaagc aagaaagaat
    42301 ttatgaaatt gtcagcagag cgagtggctc agtttatcaa gcctttcgtg atgcgacgca
    42361 agaaagaaga agttctgact gaattgccag acttgattga ggtggtttat aaaaatgaac
    42421 tggaagacca gcaaaaggct atttaccttg cccagttaca acagatgcga gaccatctgg
    42481 ctcaagtgtc agaacaggaa tttcagcgaa gtcgtgtgga aattttatct ggtttgatgc
    42541 gcttgcgtca aatatgtgac actcctgccc tgtttatgga agattatcag ggagccagcg
    42601 gcaaactaga tagtctccga gacctactgg tacaggtggc agacggcgga caccgtgtct
    42661 tgattttctc tcagttcaag ggaatgttgg aaaaaattga acaagaactg ccagacttgg
    42721 gcctgacatc ctttaaaatt acgggttcaa ccccagccaa ggaaagacaa gacatgacca
    42781 aggcctttaa ccaaggagaa agagatgcct ttctgatttc cctcaaggct ggtggggtcg
    42841 gtctgaacct gacaggtgca gatacagtga tcttggttga cctttggtgg aatcctgcgg
    42901 tggaagcgca agccattggc cgtgcccatc ggatgggtca ggaagaaacg gttgaggtct
    42961 atcgcttggt gaccaaggga accattgaag aaaaaattca ggaactccaa gaacaaaaga
    43021 aacatctggt gtcacaagta ttggacggca cagagtcacg tggtagtctg accctagcag
    43081 aaattagaga aattttggga atttctgaag ccagcacttg aaaaatcaag acaatacgct
    43141 ataatgaagt gttgaaagga aatagaaaat gaaacaagaa cgatttccat tggtgtcaga
    43201 tgacgaggtc atgttgactg aaatgccagt catgaatctc tatgatgagt ctgatctgat
    43261 cagtaatatc aagggtgagt atcgagataa aaattattta gaatgggctc ctattgctga
    43321 agaaaaacca gtaaaaccga ttgaaaagca agtagggaaa cctaaaaaag ctcctttagg
    43381 ggttaaaaaa gaaggaaaga gctatgcgga ggtggcgcgt gaagaagcgc gtgcagactt
    43441 gaaaaagaaa cgctctgcta actatctaac tcaggatttc agccttgcga gacgtcattc
    43501 tcagcccagt ctagttagac agggcaatca accgacaact cctttccaaa aggaaaatcc
    43561 tggtgaattt gtcaaatata gccaaaaatt gacccagtct cattatatct tggcggaaga
    43621 agttcattct atccctacca agaatgaaga agtgtcagca cctgctccaa agaaaaacaa
    43681 ttatgatttt ctaaagaaga gccaaatcta caataaaaaa agtaaacaaa cagaacaaga
    43741 acgtcgggtt gcccaagagt tgaatctgac cagaatgaca gaatagggga gaaaacatgt
    43801 caaagacata tcattttatc ggaattaagg gatcagggat gagtgccttg gccttgatgt
    43861 tgcaccagat ggggcacaag gttcagggat cagatgttga aaagtactac tttacccaac
    43921 gcggtcttga gcaggcagga attaccattc ttccttttga tgaaaagaat ctagacggtg
    43981 atatggaaat tatcgctgga aatgcctttc gtccagataa caacgtcgaa attgcctatg
    44041 cggaccaaaa tggtatcagc tacaaacgtt accatgagtt tctaggtagc tttatgcgtg
    44101 actttgttag catgggagta gcaggagcac atggaaaaac ttcaacgaca ggtatgttgt
    44161 ctcatgtctt gtctcacatt acagatacca gcttcttgat tggagatggg acaggtcgtg
    44221 gttcggctaa tgccaaatat tttgtctttg aatctgacga atatgagcgt cacttcatgc
    44281 cttaccaccc agaatactct attatcacca acattgactt tgaccatcca gattatttca
    44341 caagtctcga ggatgttttc aatgccttta acgactatgc caaacaaatt accaagggtc
    44401 tttttgtcta tggtgaagat gctgaattgc gtaagattac gtctgatgca ccaatttatt
    44461 attatggttt tgaagctgaa ggcaatgact ttgtagctag tgatcttctt cgttcaacaa
    44521 ctggttcaac cttcaccgtt catttccgtg gacaaaactt ggggcaattc cacattccaa
    44581 cctttggtcg tcacaatatc atgaatgcga cagccgttat tggtcttctt tacacagcag
    44641 gatttgattt gaacttggtg cgtgagcact tgaaaacatt tgccggtgtt aaacgtcgtt
    44701 tcactgaaaa aattgtcaat gatacagtga ttattgatga ctttgcccat catccaacag
    44761 aaattattgc gaccttggat gcggctcgtc agaaataccc aagcaaggaa attgtagcag
    44821 tctttcaacc gcataccttt acaagaacca ttgccttgtt ggacgacttt gcccatgctt
    44881 taaaccaagc agatgctgtt tatctagcgc aaatttatgg ctcggctcgt gaagtagatc
    44941 atggtgacgt taaggtagaa gacctagcca acaaaatcaa caaaaaacac caagtgatta
    45001 ctgttgaaaa tgtttctccg ctcctagacc atgacaatgc tgtttacgtc tttatgggag
    45061 caggagacat ccaaacctat gaatactcat ttgagcgtct cttgtctaac ttgacaagca
    45121 atgttcaata ggatgttccc atggaaattc caattaagat cattcaggca agcaagtctg
    45181 atttgcctga gataggggca cttcagacct cgtcttttcc agctgaaaag cagcaacttt
    45241 cccatatttt agaagaaagt atccgtaagt gtgcggatac ctttcttcta gctagggatg
    45301 aaaatcaact tttaggctat attttatcaa gtccccagtc agacaatccg caatgtctaa
    45361 aagtacattc tttagtcatc gagtctgacc atcagagaca gggcctggga acacttcttc
    45421 ttgcagcctt gaaagaggtg gcagttgagc tggattacaa agggattcgt ttggagagtc
    45481 ctgatgagct gctttcctat tttgaaatga acggttttgt tgatgaagaa gcaactttgc
    45541 tctatgcaac tagccagggc tatagtatga tttggtttaa tcccttttat ctggaggaac
    45601 aatgaaaatc agacaagcaa gattagaaga tttggatcgg attgttgaac ttgaatttga
    45661 aaatttttcg gtcgaagaag ccattcctcc ttctgtcttt gaagcacatt tgagagaaat
    45721 tcagacctct tttctggttg ctgaaaaaga aggaagaatc atgggttata tcgaaggacc
    45781 agttggcctg caccgccatc tgcaagacca gtcttttaca gaagaaataa aagactatag
    45841 tcatgagcct ggtggttata tctctgtgac ctgtctgtct attgccaagg aggcacaggg
    45901 actcggactg ggtcagaaat tgctgacagc cttgaaagaa gttgctcttg aagatgagag
    45961 agatggcatt aatctaactt gtcatgacta tctcatcgcc tattatgaaa aacatggatt
    46021 tgtcaacgaa ggccagtccc agtcaacctt tgcaggggaa acatggtatg atatggtctg
    46081 ggaaatgaaa aaataagtta ggaaaagtat catagattgc tttttttgga cttttaagat
    46141 ataatattat ggattatcaa caaggaggaa aaacttttga gtgaaaagtc aagagaagaa
    46201 gagaaattaa gctttaaaga gcagattctg agagatttag aaaaagtaaa aggctatgat
    46261 gaagttctga aagaagatga ggcagtagtt cgcactcctg caaatgaacc ttcaactgaa
    46321 gaactcatgg ctgattcctt gtcaacggta gaggagatta tgagaaaagc tcctaccgtg
    46381 cctactcacc caagtcaagg tgtaccagct tctccagcag atgagattca aagagaaact
    46441 cctggtgttc caagtcatcc aagtcaagat gtaccttctt ctccagcgga agaaagtgga
    46501 tcaagaccag gtccaggtcc tgttagacct aagaaacttg aaagagaata caatgaaacc
    46561 ccaacaaggg tagctgtttc ctatacgacg gcagagaaaa aagcagaaca agcaggtcca
    46621 gaaacaccta cgcctgctac agaaacagtg gatatcatca gagatacatc acgtcgtagc
    46681 cgtagagaag gagcaaaacc cgttaagcct aagaaagaga agaagtcaca tgtgaaagct
    46741 tttgtgattt cattccttgt attccttgcc ttgctctcag caggtggtta ctttggttac
    46801 cagtacgtgc tagattcctt attacctatc gatgctaatt ctaagaaata tgtgacggtt
    46861 ggaattccag aaggttcaaa cgttcaagaa atcggtacga cgcttgaaaa agctggtttg
    46921 gtaaagcatg gtctgatttt tagtttttat gccaagtata aaaattatac cgacttgaaa
    46981 gcaggttact acaatttgca aaagagtatg agtacagaag acttactcaa agagttgcaa
    47041 aaaggtggaa cagatgaacc gcaagaacct gtacttgcga ctttgacaat tccagaaggt
    47101 tataccttgg atcagattgc tcaaactgtg ggtcaattgc aaggtgactt caaagagtct
    47161 ttgacagcgg aggctttctt ggctaaagtt caagatgaga cgtttatcag tcaagcagta
    47221 gcgaaatatc ctactttact ggaaagtttg cctgtaaaag acagcggtgc gcgttatcgt
    47281 ttggaaggat accttttccc agctacatac tctatcaagg aaagcacaac tattgagagc
    47341 ttgattgatg agatgttagc tgctatggat aagaacctat ctccttacta tagtactatc
    47401 aaatctaaaa acttgactgt caatgagttg ttgaccattg cttccttggt cgaaaaagaa
    47461 ggtgccaaga cagaagatcg taagctcatt gcaggtgtat tctacaatcg tttgaatcgt
    47521 gatatgccac ttcaaagtaa tattgcaatc ttgtatgccc aaggaaaact ggggcaaaat
    47581 atcagtctag ctgaggatgt tgcgattgat accaacattg attcacctta taatgtttat
    47641 aaaaatgtag gtctcatgcc tggtccagtc gatagtccaa gtctggatgc gattgagtca
    47701 agcatcaatc aaactaagag cgataacctc tactttgtag cagatgtcac agaaggcaag
    47761 gtctactatg ctaacaatca agaagaccac gaccgcaatg tcgctgaaca tgtcaacagc
    47821 aaattaaact aaacaaacta aaattatgtg atacttcaca taattttctt tagaaaatat
    47881 tatcagaaga aagttgagaa aaatggcaga aaaaacatat cctatgaccc ttgaggaaaa
    47941 ggaaaaactt gaaaaagaat tagaagaatt gaaattggtt cgtcgaccag aagtggtaga
    48001 acgcattaag attgcccgtt catacggtga cctttcagaa aacagtgagt acgaagcagc
    48061 taaggatgaa caagcctttg tcgaaggaca aatctctagc ttagaaacaa aaatccgcta
    48121 tgctgaaatc gtcaatagcg acgcagttgc ccaggacgaa gtagcgattg gtaaaacagt
    48181 caccatccaa gaaattggtg aggacgaaga agaagtttat attatcgtag gttcagctgg
    48241 tgcggatgcc tttgcaggta aggtttcaaa tgaaagccca attgggcagg ccttgattgg
    48301 caagaaaaca ggtgatacag caaccattga aacgcctgtt ggtagctatg atgtaaaaat
    48361 cttgaaggtt gaaaaaacag cctaaaaaca gaaaaaggag tggggaggcg atgtgcttca
    48421 ctcactcctt tttccatttt gctattcttc gaaaatatct tcaaaccacg tcagcgtcgc
    48481 cttgccgtat gtatggttac
//
LOCUS       DAVDHC010000013        46146 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVDHC010000013 DAVDHC010000000
VERSION     DAVDHC010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46146
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.013"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..217)
                     /locus_tag="VUR43_001050"
     CDS             complement(<1..217)
                     /locus_tag="VUR43_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HET5412752.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAA"
     gene            complement(286..555)
                     /gene="blpJ"
                     /locus_tag="VUR43_001051"
     CDS             complement(286..555)
                     /gene="blpJ"
                     /locus_tag="VUR43_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET5412753.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(1022..1219)
                     /gene="blpI"
                     /locus_tag="VUR43_001052"
     CDS             complement(1022..1219)
                     /gene="blpI"
                     /locus_tag="VUR43_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET5412754.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            1501..2088
                     /locus_tag="VUR43_001053"
     CDS             1501..2088
                     /locus_tag="VUR43_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET5412755.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            2015..3658
                     /locus_tag="VUR43_001054"
     CDS             2015..3658
                     /locus_tag="VUR43_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET5412756.1"
                     /translation="MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVI
                     TYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDA
                     NSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
                     KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYS
                     ILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQT
                     KLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDIN
                     LTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINY
                     LPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAG
                     LSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRL
                     SIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            3669..5030
                     /locus_tag="VUR43_001055"
                     /pseudo
     CDS             3669..5030
                     /locus_tag="VUR43_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            5087..5242
                     /gene="blpC"
                     /locus_tag="VUR43_001056"
     CDS             5087..5242
                     /gene="blpC"
                     /locus_tag="VUR43_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET5412757.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGWWEELLHETILSKFKITKA
                     LELPIQL"
     gene            complement(5284..6624)
                     /locus_tag="VUR43_001057"
     CDS             complement(5284..6624)
                     /locus_tag="VUR43_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5412758.1"
                     /translation="MNITWILLYALVINGLEIVIFFKVDGIGLTFDRIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNIRDRALKSLLAGKFIKAREKNIVFNVEVPEEI
                     QVEGMSLLDFLTIVSILCDNAIEASAEASQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTNLNTTCQNQVFRQVLTVIHAE"
     gene            complement(6638..7375)
                     /locus_tag="VUR43_001058"
     CDS             complement(6638..7375)
                     /locus_tag="VUR43_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5412759.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSTEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7380..7718)
                     /locus_tag="VUR43_001059"
     CDS             complement(7380..7718)
                     /locus_tag="VUR43_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5412760.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKQGE"
     gene            7994..8323
                     /locus_tag="VUR43_001060"
     CDS             7994..8323
                     /locus_tag="VUR43_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET5412761.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8491..9540)
                     /locus_tag="VUR43_001061"
     CDS             complement(8491..9540)
                     /locus_tag="VUR43_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5412762.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFCQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNSDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9537..10268)
                     /locus_tag="VUR43_001062"
     CDS             complement(9537..10268)
                     /locus_tag="VUR43_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412763.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10336..10746
                     /locus_tag="VUR43_001063"
     CDS             10336..10746
                     /locus_tag="VUR43_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET5412764.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10756..11043
                     /locus_tag="VUR43_001064"
     CDS             10756..11043
                     /locus_tag="VUR43_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412765.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(11365..12501)
                     /gene="dnaJ"
                     /locus_tag="VUR43_001065"
     CDS             complement(11365..12501)
                     /gene="dnaJ"
                     /locus_tag="VUR43_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET5412766.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12903..13259)
                     /locus_tag="VUR43_001066"
     CDS             complement(12903..13259)
                     /locus_tag="VUR43_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HET5412767.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(13261..15084)
                     /gene="dnaK"
                     /locus_tag="VUR43_001067"
     CDS             complement(13261..15084)
                     /gene="dnaK"
                     /locus_tag="VUR43_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET5412768.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15564..16088)
                     /gene="grpE"
                     /locus_tag="VUR43_001068"
     CDS             complement(15564..16088)
                     /gene="grpE"
                     /locus_tag="VUR43_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET5412769.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSKLDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(16115..17149)
                     /gene="hrcA"
                     /locus_tag="VUR43_001069"
     CDS             complement(16115..17149)
                     /gene="hrcA"
                     /locus_tag="VUR43_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET5412770.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17313..17750)
                     /locus_tag="VUR43_001070"
     CDS             complement(17313..17750)
                     /locus_tag="VUR43_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET5412771.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            complement(18482..18619)
                     /locus_tag="VUR43_001071"
     CDS             complement(18482..18619)
                     /locus_tag="VUR43_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412772.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            18877..18996
                     /locus_tag="VUR43_001072"
     CDS             18877..18996
                     /locus_tag="VUR43_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET5412773.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            complement(19086..20432)
                     /gene="glnA"
                     /locus_tag="VUR43_001073"
     CDS             complement(19086..20432)
                     /gene="glnA"
                     /locus_tag="VUR43_001073"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET5412774.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(20469..20825)
                     /gene="glnR"
                     /locus_tag="VUR43_001074"
     CDS             complement(20469..20825)
                     /gene="glnR"
                     /locus_tag="VUR43_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET5412775.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            complement(20902..21429)
                     /locus_tag="VUR43_001075"
     CDS             complement(20902..21429)
                     /locus_tag="VUR43_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET5412776.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFCFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            complement(21565..22761)
                     /locus_tag="VUR43_001076"
     CDS             complement(21565..22761)
                     /locus_tag="VUR43_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET5412777.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            complement(22851..27830)
                     /locus_tag="VUR43_001077"
                     /pseudo
     CDS             complement(22851..27830)
                     /locus_tag="VUR43_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
     gene            28123..29754
                     /locus_tag="VUR43_001078"
     CDS             28123..29754
                     /locus_tag="VUR43_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET5412778.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            complement(30313..31920)
                     /locus_tag="VUR43_001079"
     CDS             complement(30313..31920)
                     /locus_tag="VUR43_001079"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET5412779.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(32310..32897)
                     /locus_tag="VUR43_001080"
     CDS             complement(32310..32897)
                     /locus_tag="VUR43_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET5412780.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(33025..33474)
                     /locus_tag="VUR43_001081"
     CDS             complement(33025..33474)
                     /locus_tag="VUR43_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HET5412781.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            complement(33479..33868)
                     /locus_tag="VUR43_001082"
     CDS             complement(33479..33868)
                     /locus_tag="VUR43_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET5412782.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(33896..34522)
                     /locus_tag="VUR43_001083"
     CDS             complement(33896..34522)
                     /locus_tag="VUR43_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET5412783.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(34536..35099)
                     /locus_tag="VUR43_001084"
     CDS             complement(34536..35099)
                     /locus_tag="VUR43_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5412784.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(35264..35498)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(35552..36055)
                     /locus_tag="VUR43_001085"
     CDS             complement(35552..36055)
                     /locus_tag="VUR43_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET5412785.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(36248..37078)
                     /locus_tag="VUR43_001086"
     CDS             complement(36248..37078)
                     /locus_tag="VUR43_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET5412786.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(37063..38745)
                     /locus_tag="VUR43_001087"
     CDS             complement(37063..38745)
                     /locus_tag="VUR43_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412787.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            complement(38856..39104)
                     /locus_tag="VUR43_001088"
     CDS             complement(38856..39104)
                     /locus_tag="VUR43_001088"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412788.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            complement(39111..39659)
                     /locus_tag="VUR43_001089"
     CDS             complement(39111..39659)
                     /locus_tag="VUR43_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET5412789.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(39674..40522)
                     /locus_tag="VUR43_001090"
     CDS             complement(39674..40522)
                     /locus_tag="VUR43_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET5412790.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            40711..42060
                     /gene="trkA"
                     /locus_tag="VUR43_001091"
     CDS             40711..42060
                     /gene="trkA"
                     /locus_tag="VUR43_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET5412791.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            42064..43503
                     /locus_tag="VUR43_001092"
     CDS             42064..43503
                     /locus_tag="VUR43_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET5412792.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(43629..44087)
                     /locus_tag="VUR43_001093"
     CDS             complement(43629..44087)
                     /locus_tag="VUR43_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
                     /protein_id="HET5412793.1"
                     /translation="MEVVLFSYCLNTRYLLQIVDIASSNDIILEEDTSEIMPGEIDVI
                     KSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILA
                     PQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            45430..45714
                     /locus_tag="VUR43_001094"
     CDS             45430..45714
                     /locus_tag="VUR43_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412794.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQNLMEKYKHG"
     gene            45707..45856
                     /locus_tag="VUR43_001095"
     CDS             45707..45856
                     /locus_tag="VUR43_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412795.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVD
                     AFMAL"
     gene            45971..>46146
                     /locus_tag="VUR43_001096"
     CDS             45971..>46146
                     /locus_tag="VUR43_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5412796.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPS"
BASE COUNT        13865 a        10061 c         8238 g        13982 t
ORIGIN      
        1 ttgctgcata ggctacacct ccaagtatag ctccacccgc agcaccagtt gctgcacctt
       61 gccatgttcc tgttttaatg cctagttgaa gacctcttgc tgctcctcct ccaacacctg
      121 ctttggcaaa atctccccaa ttgcatccgc caccttcaac gcaagcaagc atttcagtat
      181 ccataacaga aaattgtgac atcatttttg tatccatgac aaatactcct tttttaaaaa
      241 actaaaataa atcagaatag aatcctcata attttactat aagtcttacc aacttagtcc
      301 caatttatca ccaaccatac ctcctaagca tgttaatcca cccccaattg caccaatgtg
      361 tgctccaaca aatgcaccag caagtccagc tactcctaaa gtggccaaac ctgctccagt
      421 tccaccagtt ataattcccg tagtgactcc tgtaatcagt gcattttgac aatcagtgga
      481 gctatacccc ccttcaactt tcgcaagcat ttcagtatcc ataacctcta actgtgacaa
      541 catttttgta ttcatgatga atacctcctt tttattttca atttgttacc aaagtcttaa
      601 attcaataaa caaatagatt ttttatagta tctttttgat tttcttaaaa aagtatatac
      661 gtctactatc ttcttaaagg tagcagtacc tattttttag tctaagattt caataatctt
      721 gagtatctaa aatatcttaa tttcgttatt ctccttgcaa taaaaagttt tactatacta
      781 tttattaact tgcagaaagc aaaaaatatt agtaaataat agtttatagt taagtttttt
      841 attcctacca atccatcaac taagtaaagc atcaacgatt acataaacga ttgataatat
      901 aattaaaatt ttgctaacta tcttattctc atcattctta gataactttg atattttgta
      961 agtaagtaaa taagacagta aattaatagc gataataata ctatatttaa gaatcataat
     1021 cttacaaaga ggacataatt cctgaaccta cacaaataag tgttgctgct cccccagtta
     1081 tcggaccagt cgcagcagct aatagtactg ctccaataca accaccgatt gcagatccta
     1141 aattgcctct tcctccacta actatttcga gttcttcatt atccataaca gaaaattgtt
     1201 ccatcatttt tgtattcatg acaaatactc cttttttctt tttttatttt tgtcttgttg
     1261 taactttgat aagtttagta tatcatcgtt ttttaaaatt tttcatccag atcttgaatt
     1321 gtcatcgaaa cgtcttgaat tagctttttt atttcaagcc acctctaaat gtttaaaaaa
     1381 aataatttct aatcactttt ttaccattca ggaagtttta atgactattc aagatttcat
     1441 aaaatatgaa cttagtttta tgacataata gacctatcca ctatatgaaa ggaattgcca
     1501 atgacttctt ataaacgtac atttgttcct caaatagatg cgagagactg tggtgtcgct
     1561 gccttagcct cgattgctaa attctatggt tcagattttt ctctagctca cttgagagaa
     1621 cttgcaaaga ccaataaaga agggacgact gctcttggca ttgtaaaagc cgctgatgaa
     1681 atgggctttg aaacaagacc tgttcaagca gataaaacgc tctttgacat gagtgatgtc
     1741 ccctatccat ttatcgttca cgttaacaaa gaaggaaaac tccaacatta ctatgttgtc
     1801 tatcaaacaa agaaagacta tctgattatt ggtgatcctg acccttctgt aaaaatcact
     1861 aaaatgtcaa aagaacgctt tttctatgaa tggactggag tagctatttt tctagctacc
     1921 aaacccagct atcaacccca taaagataaa aagaatggtc tactaagcaa gcttccttcc
     1981 tctgattttc aaacaaaaat ctctcattgc ttacattgtt ctctcaagct tattggtcac
     2041 tattatcaat ataggtggtt cttactatct ccaaggaatc ttggatgaat acattccaaa
     2101 tcagatgaaa tcaactttag gaatcatctc agttggtctg gttatcacct atatcctcca
     2161 acaagtcatg agcttctcca gagattatct cctaaccgtt ctgagtcaga gattaagtat
     2221 tgatgtgatt ttatcctata ttcgccatat ttttgaactt cccatgtctt tctttgcgac
     2281 acgtcgtaca ggagaaatca tttcacgatt cacagatgct aactctatta tagatgcctt
     2341 ggcttctacc attctttctc tttttctgga tgtttctatt ctgattcttg taggaggcgt
     2401 cttactggca caaaacccta atctcttcct tctttctctt atttccattc ctatatacat
     2461 gttcatcatc ttttctttta tgaaaccttt cgaaaaaatg aaccatgatg tcatgcaaag
     2521 taattctatg gttagctctg ccattatcga agatatcaac gggattgaaa ctataaagtc
     2581 gctcacgagt gaagaaaatc gctatcaaaa tatagacagc gaatttgtag attatttgga
     2641 aaaatccttt aagctcagta aatattctat tttacaaacg agtttaaagc agggaacaaa
     2701 attagttctg aatatcctta tcctatggtt tggcgctcaa ttagtcatgt caagtaaaat
     2761 ttctatcggt cagctgatta cctttaacac acttttttct tactttacaa ctcctatgga
     2821 aaatattatc aacctccaaa ccaaactcca atctgcgaag gtcgctaata accgtttgaa
     2881 cgaagtctat ctagtcgaat ctgaatttca agttcaagaa aaccctgttc attcacattt
     2941 tttgatgggc gatattgaat ttgatgatct ttcttataag tatggttttg gacgagatac
     3001 cttaacagat attaatctca cgattaaaca aggagataag gttagcctag ttggagttag
     3061 tggttctggt aaaacaactt tagccaaaat gattgtcaat ttctttgaac cctacaaagg
     3121 gcatatttcc atcaatcatc aggatattaa aaacattgat aaaaaagtct tgcgccgtca
     3181 tattaattac ctaccccaac aagcctatat ctttaatggc tctattttgg aaaacttaac
     3241 cttgggcggt aatcatatga ttagtcaaga agatattcta aaagcttgtg aagtagctga
     3301 aatccgtcaa gacattgaaa gaatgcctat gggctatcaa actcagctct ctgatggagc
     3361 tggtctatca ggaggacaga agcaacgaat cgctctcgct cgtgctcttt taactaaatc
     3421 tcctgtttta atactagatg aagctactag cggtcttgat gtcttgactg agaaaaaagt
     3481 tatagataat cttatgtccc taactgataa aaccattctc tttgtagccc atcgtctcag
     3541 tatagccgaa cgaaccaacc gtgtcattgt tcttgaccag gggaaaatca ttgaagttgg
     3601 tagccaccaa gagttaatgc aggcgcaagg tttctaccat catctattca ataaataagg
     3661 agaatgtcat gaatcctaat ctttttagaa gcgtcgagtt ttatcagaga cgttaccata
     3721 actatgcgac agtgttaatt atacctcttt cattactatt tactttcatc ttgattttct
     3781 cccttgttgc cacaaaagaa attactgtca cttcccaagg agaaatcgcc cctacaagtg
     3841 tcatttcatc tattcagtca accagtgata atcctatcct tgctaatcat ttagtggcaa
     3901 atcaagtagt tgaaaaaggg gacttactca tcaaatactc tgaaacaatg gaagaaagtc
     3961 agaaaactgc cttagcaact caattacaaa gacttgagaa gcaaaaagaa ggacttggaa
     4021 ttttgaaaca aagctgagaa aaagcgactg atcttttttc tggcgaggat gaatttggct
     4081 accataatac ctttatgaat tttactaaac aatcccatga tattgaactg ggtatcacaa
     4141 agactaacac tgaggtttca aatcaagcta atcttgccaa tagcagttca tcagctattg
     4201 aacaagaaat tacaaaagtt caacaacaaa ttggagaata tcaagagctg agagatgcta
     4261 tcataaataa cagagcacgc ttaccaacta gcaatccaca ccagtcaatt ttgaatcgtt
     4321 atcttgtagc ctcacaagga caaacacaag gaacggcaga ggagccattt ttatctcaaa
     4381 ttaatcaaag tattgcaggt cttgaatcat ctatcgcaag cctcaaaatt cagcaagctg
     4441 gtatcggaag tgtagcaact tatgataata gtttagcaac caaaattgaa gtactccgca
     4501 ctcagttttt acaaacagcc tcacagcaac aactaaccgt ggagaaccaa ttaacagaat
     4561 taaaagtaca actagatcaa gcgacacagc gcttagaaaa caatacctta accgctccaa
     4621 gtaaaggtat cgttcatctg aacagcgaat ttgaaggtga aaatagaatt ccaactggta
     4681 cagaaattgc tcaaatattc cctatcatca cagatacaag agaagtacta atcacttact
     4741 acgtagcttc tgactatcta cctctactag ataaaggaca aactgtaaga ttaaaactgg
     4801 agaagattgg aaatcacggc attaccatca tcggccaact tcagacaatt gatcaaactc
     4861 ctaccagaac agagcaaggc aatctcttta aattaaccgc tcttgcaaaa ctatctaatg
     4921 aggatagtaa actcatccaa tatggcttac aaggtcgcgt cactagtgta actgcaaaga
     4981 aaacatattt tgattatttc aaagataaaa ttttaaccca ttctgattaa ttttcagata
     5041 acactctata actatttatt atcttatcaa aaaggagaat cataacatgg ataagaaaca
     5101 aaacctaact tcatttcaag aactaacaac taccgaactc aaccaaatta caggtggagg
     5161 atggtgggaa gaactcttac atgaaacaat tttaagtaaa tttaaaatca caaaagcact
     5221 tgaactacct attcagctat aaaaacaaga ccgagaaaca agaactctcg gtcttgtttt
     5281 ttatcattct gcatgtatca cagtaagtac ctgacgaaag acttgatttt ggcaggtagt
     5341 atttagattg gtattgggat gactttccac aattttcata acggtataga gaccaactcc
     5401 tctctcctcc cctttagaac ttgctccaaa ggagaagatt tcagaaatat cgatgccctc
     5461 ttctttgatg gagttttcaa tgataaaagt ctcctgtgct ccatttttta aaaaggcgat
     5521 tgaaacatga ggttgactgg cctctgcact agcttcaata gcattgtcac aaaggataga
     5581 cacaatggtt agaaaatcaa gtaggctcat cccctcaacc tgaatctcct caggaacttc
     5641 aacattaaag acaatgttct tttctctagc ttttataaat tttccagcta ggagactctt
     5701 gagggcacgg tcacgaatat tcaccaatct gcccaggtca tatttattgt cctgcaattt
     5761 ctgactggaa tcccttaaga ccgagtcgta gatctctttt atctgctcca tatcctcctc
     5821 ttcaatgccc aaacgtaagc tggttaagag gttagtgtag tcatggcgaa aactccgaat
     5881 ttccttgtaa agttcctcta tatgccgact atagcgttcc atatctctgt agcgcaaggt
     5941 ctgctcttgg ttcagttcct cctgaagttt ttccttcaaa taggtatcca atttcttgat
     6001 accccccata aaaaagagta ggtaaaacac taggatgaga tggcgaacag tcgttgattg
     6061 aataccttgt tcatattcaa ggtaagatag actttgcatc actagataat aagcccccat
     6121 tgcccagtta atcttagtaa gagacttttg aaaacctgta tctagaaact cccttctcaa
     6181 tctagtgaaa tcatagtcta accatttcaa aaagactaaa actatgaagc aaacgaatat
     6241 cataatcaat aaaaagatag gattgccatc cccatctaca attccttgcc ccaaaaatgg
     6301 aagcacaaaa taggaaacac ctctgtaaaa gagctctact aatatcattg ggaagagacc
     6361 ataaaaaata aggatttttt taggaagccc tcttaacaat aagaaagata gacctatacc
     6421 gaacaaaggt tctataaaat aggacaaata tttacttaca gccaaaaatt gaaaagtcgt
     6481 aaaaatgatc cctagaagaa atttcagaag aaaggcctta aaaattctat cgaaagtgag
     6541 accaattcca tctactttaa agaaaatgac aatttctagt ccattaataa caagtgcata
     6601 caacaatatc caagtaatgt tcataaactc tcctagctca gtgtaagtta ttaatagcct
     6661 cagacacttc cctgacctta taacgcgcga tcagacaact tccaccattg ggaaagaaaa
     6721 ggagtttttc tttcttatcc aaatgcacca catttgcagg attgatgaga aaagagcgat
     6781 ggcactgcaa gagacggggt tcctgcttga aaacctcctc taaactcgct gtaaattcca
     6841 gcctgtctgt cttggtatag agaataacac gatggggtct tggggatgtt tcgagatagt
     6901 aaacctcttt aaaaggatac tgaaattggg caaattttga tttaaagtaa aagcaatctt
     6961 ccgccagact tttactatct tgactattgg catagaggag ggctgtctcg attcgagatt
     7021 caaactcctc tgtcgaaagg gccttatcaa tatagtccag agcagacact tggtagcgaa
     7081 aggacagggg cataaactcc gagtgagtcg tcacaaagac aatcagggca taggggtctt
     7141 gttcccgaat ctttctagcc acttccagcc ccttcatctc ctcatttcga atctcaatat
     7201 ccaaaaagaa tagctgatgg gcccccttct catgcacctc tgccagcagt tggtctggct
     7261 tgccaaatac ctcaaaagag ctgggagtga tatgatgttc cttcaagagt ttctcaatcg
     7321 tcgtttcaat cctagtctgt tgggaaaaat catcctctaa aacaaatatt ctcatctttt
     7381 tactctcctt gttttaacca tttttgacga atttctctat agcgacgtct ggcatacttg
     7441 acagcgtatt gaccttcttc tccgagaaaa aggattcttt cttgaaaatc aatcgatttt
     7501 aatttatcaa gattaaccaa acaatttcga tgacatctca tcaaggtttc cccacattgg
     7561 ttctcaagat tacttaaatt ttgaagcata ttaaaactag cttcttctgt aacaatctgt
     7621 acggtatggg ctttagttgg atgtgtttgg atatagtaga tatcgtcgat gtttacttta
     7681 tagactgttt tctgcgtctg aataatcata tatttcattg gattctcctc ctaagaaaag
     7741 aataacagaa aaggtctagc ccaagcacac ccaatcctaa acagtctttg aaaactccta
     7801 aaaggattat tttctacaac atcatgatga gcttacaact attttatcat aaaattcact
     7861 cagcgcaatt caagacattt caatgacaat taaagatttg aataaaaaaa aagaattaaa
     7921 agtgataaac taacagtatc aaaacacagt tgccagaagt aagactggca cccagattaa
     7981 aggaggcatt cccatgacag atacagaccc catcaaaaga gctcatactt tgattactga
     8041 cttaaacaaa gcctaccaag catgcaaaca ggcaagcgct gacgacgtcc gctttcagga
     8101 gcaattaaac tctattcttg gttttctagc caaggctgaa acagtggata atcgattctt
     8161 gattgaacta gaaaaatttt accagacttc cagtcttctc atgggactca gcgctcttga
     8221 tccagatgct ccaactcgcg ccgcttggcg ggcctatgac cgcttccact ttgaccaagt
     8281 caagaccaag ttaatactca atgaaaatca aagagcaaac taggaagcta gccgcaagct
     8341 gtacttgagt acggtaagac gacgctgacg tggtttgaag atattttcga agagtataag
     8401 tctctacgga ccaaccatta tcctgtagta acaaaaaaga agctgagaca aactgaactc
     8461 aacttctttt ttagtgtcgt atcagcaatg ttagtcctgc atctgacgtt ttacctgata
     8521 aggcaaatac aagactagta aaaccaaacc agctcctagt aaggctagaa gggctagttt
     8581 ttcttggaag gtaatcaacc caacaactaa ttccacaagt aaaacaaaac tggtcaatcc
     8641 tcgaactacc tcctgtaagc ctttttcctt ttgccccttg tccagcggaa agagttgggt
     8701 caaatactgg tagtcaaagg catgatagag ggccagcaac tggaagagca agaggtagtt
     8761 aaagagaact accactgctg tcgcaatcca agcttgctcg ataaaaacct gcgccagtac
     8821 ggaaagtaag agaagacgaa gactgagagc aaagaggtcg ctatttcgca gataagaacg
     8881 cagatagaga ttttgccaaa tcttcccagg caccttctga acagccttta aaataaagtc
     8941 cagataggca cgacgcttaa cgctgtttga aattcccttg acctgcgtaa agagggcaaa
     9001 gaaacgaagc aagacttgct tacgcttgct ttcttgagaa ataagatagt cccagtccag
     9061 tccagtttca gtgaaaaatt tgctggcctt ttgacaaaag tggaaatatt ttcctacccc
     9121 caataaaagc acatagagca gaaaaactgg caagccataa cccattgcta aaaataaagg
     9181 cgcaaataac agcaagaaaa gggtctgtac aaagagccaa aagactaggg aaatgccagt
     9241 ttgacgcttg agatggagct tgatttcctc ttctccgact aagagaaaga gcttgtctgg
     9301 agcctccata taggtggcaa ttcctcccca aagtaaaagt aaaacagacg taattcctac
     9361 aaacaaaagg ataggccaat gattttcagg aaaatgttgt aagagttgac tgtactggta
     9421 ggctagaaag cccaacagga caagcaggaa caagacaaag tggtcattga gcacatagcg
     9481 cagataacca agacactcct tacgaaaggc ctgctttctc tttaaaaaca agtctttcat
     9541 aggtcctcct cttttgtcag agccaagtaa atatcattca aactagcctc aggcatatca
     9601 aaggcttcgc gtagttgcag gagattgcct ttggcacgca cctctccctt gtgaagaatg
     9661 acaaaggcat cacacatctt ctccgccgaa tccagcacgt gggtactcat gagaatagac
     9721 ttgccctttt gcttctccac ttccaaaagc tgaatcaaat cagaaatagc tagcggatca
     9781 agaccaagga aaggctcatc cacgatgaaa agacttggat ccaccacaaa agcacagata
     9841 atcatgacct tctgcttcat cccttttgaa aaatgaacag ggaaccagtc taatttctgg
     9901 tccagacgga acatctttaa caagggctct actcgttcga aagccacttt ttgctcaata
     9961 ccgtaagcca tagcaaccgt ttcgatatgc tctctgaggg tcaattcctc atacagacta
    10021 ggcgtctcag gaatgtagcc aatctgcttg cggtagctag tcgcatctcc ttgcagagtc
    10081 aggccattga tattgatgga gccactataa ggtgccaaca gaccgataat ctcattgatc
    10141 gtcgttgatt tcccagcacc attgagacca atcaaaccga ccaactgccc actttcaaca
    10201 gtaaaggaca catctttcaa aacaggaaca tgaacatagc cacctgtcag gtttttaatt
    10261 tctaacatat tttctccaaa tctggtataa tgtagctata ttatatcaaa attcagtaca
    10321 gtagaggtag attttatgtc agattgcatt ttttgtaaaa tcatcgcagg ggaaattcct
    10381 gcttcaaaag tatatgaaga tgagcaggtc cttgcctttc ttgatatctc tcaagtaaca
    10441 ctaggacaca ccttggtcgt gccaaaagaa cactatcgca atcttttgga gatggatgct
    10501 acgagcgcca gccaactctt tgcccaagta ccaaaagtag ctcaaaaagt catgaaagtc
    10561 actaaggctg ctggtatgaa tatcatttcc aactgtgaag aagtcgctgg tcaaacagtt
    10621 tttcatactc acgttcacct tgtgcctcgc tacagtgctg acgatgacct caagattgat
    10681 tttatcgccc acgaaccaga ctttgacaaa cttgctcaag tcgctgaaac catcaaaaac
    10741 gcttaaggag ttgctatgaa attatccaac ctactgctat ttgcaggagc tgcagccgga
    10801 agttatctgg ttacaaaaaa tcgccaaacc atcacagatg aagtcttgaa taccactgac
    10861 cgcgttcaag ctatcaagga cgatgtggat attatccaaa acagcctgca aatcattaac
    10921 cagcaaaaag aacttatcaa ggaataccaa gaagacttga cttacaagtt taaggtcttg
    10981 gaaaaggata tccagactag actagctgtg ataaaagaaa tgcagggaac tgaagataag
    11041 taaaaagagc cccccggctc ttttttaaaa cgtaaacaag ttatagtgaa ttgaatttag
    11101 aatagcacac catagtttct aaaacattgt tagagattac tttaaaatcc tcttatcaat
    11161 ttgttcatat tctatttcaa tctattatat atatcccatc aactatgcat cataatttag
    11221 gtaactcata ctcaatgaaa atcaaaaagc aaactaggaa actagccacg ggctgctcaa
    11281 aacactgttt tgaggttgta gatacgactc acatatatac ggcaagccga cgctgacgtg
    11341 gtttgaagag attttcaaag agtattattc tccatcaaag gcatctttaa tatgatcaaa
    11401 gaagcctttt ttctttggat ttactttcaa gtcaccagca gccgcgaatt ctttcaaggc
    11461 tactttttgg cggtcgttca agcctgtcgg tgttacgaca ttaacagtaa cgtattggtc
    11521 accaactgca ccgccacgaa ggctcggtgc ccccttacta cgtaggcgga atttcttacc
    11581 agtctgagtt ccctctggaa taaccaattc aacatcaccg tgaacagttg gaatatctac
    11641 tgtatcacca agagccgctt ggacaaagtt gaggttgaga ttgtagaaga tagtcgttcc
    11701 ttcacgttca aacttgtcgc tagcttccac agaaactact acatacaagt caccataagg
    11761 tccaccgtta aagcctgctt caccttgacc agcgaggcga atttgttgac ctgtttccac
    11821 accagcaggg attttcacat gtacgctatg agcttgtttc tcatgacctg ttccatgaca
    11881 ggttgtacat ggatatttga tttcttttcc ttggccgtga cagacatcac aggttacttg
    11941 gcgacgcatc ataccaagag gagtctgcgt atcgacgtta atgacaccag cgccatgaca
    12001 gcgtccacaa gtgactggac ttgtccctgg cttagcacca gagccattac atgtacgaca
    12061 gccagcttca cgatgatact taacttcctt ctcagttccg aagatagctt cttcaaaggt
    12121 caaattgaca cgatactgga gatcatctcc ttggcgagga gcgtttggat tgcgcgaaga
    12181 accgcctccg ccgaagaaac ttgagaaaat atcctcaaaa ccaccgaagc cacctgcccc
    12241 attgaaaccg ccgaaaccac catctccacc aaaaccacca ttggcgcctg cagcaccata
    12301 ctggtcatag gcagcacgtt tttggtcgtc actcaaagtc tcataggctt cttgaacttc
    12361 cttgtacttg tcctcagcac caggctcctt gttgatatct gggtgatatt ttttggaaag
    12421 cttacgataa gcctttttga tttcgtctgc cgaagcgttt ttggataccc ccagacgatc
    12481 ataaaattca gtattgttca taattcaaga tacaaagggc gtcaaacgga cacagccatc
    12541 taggagtttt gacgacggac gcttatgtcc tagaaaaaac tatctttttg gcacagtccg
    12601 tagcccgtgt tcagttacga acacccttat tcctttctat tgatgttctg aatcgaacca
    12661 ccatttaggt cggattcaat tcctttcttt tatatttagt aagaaattct gaaacccgtg
    12721 ttcagttacg aacactcttt gttcctttct attgatgaga caaaacccaa acaaatgaga
    12781 ttccgtccct ttttatcgaa aaacagaggc tgggttgcaa cctctgcaaa taagtaaatt
    12841 aactttattt tgattttaaa tatcctataa gtacagaaat atttatatat ttttgtctct
    12901 tcttagtatt tgcctatata attccaattg atcataagaa atacaactac tgtccaaatc
    12961 ataccaatta tgaacggtat tacaaattta tatgtttgta tttctaatga tatcatagct
    13021 gataccatcg ccgatacaaa tgcagacaac aatactgaag taacaaaatt ccttaccgct
    13081 tcatcatttt tgacacaact atcatgctca gctaatataa tttctctata tatagtcaaa
    13141 cattctactg gaatattatc tataaaacct tttgctgctt catagttgtc agcttgatta
    13201 caaaaatcat tataaacttt tcgtgtattt tttagatact catcatccaa tacactcatc
    13261 ttatttttcc gtaaactctc cgtctacgac gtcatcgcct gcgtttcctg ttgcttgtgc
    13321 gccttctgct ccttcttgag cttgttgcgc tgctgcggct tgttcgtaga gtttcacagc
    13381 aaggccttga gctttttcgt tcaacgcttc aagtttcgct ttcatgtcgt ccaagttgtt
    13441 gtcttcttga gctttcttaa ggtcatcaag ggcagcttgg gcagcgtcac gttctgcgtc
    13501 gaagccttta ccttcagttt ccttgattgt cttttcagtc gcaaagattg cttggtctac
    13561 ttcattacga aggtctactt cttctttacg tttcttatca gcttcagcgt ttgcttctgc
    13621 atctttcatc atgcggtcga tttcttcgtc agtcaaacct gagttcgatt ggatgacaat
    13681 agtttgttct ttttgagttc caaggtcttt ggccttaaca gacacgatac cgttcttgtc
    13741 gatgtcaaat gttacttcga tttgaggaat tccacgaggt gcagctggga tatcagtcaa
    13801 ttggaagcgt ccaagagtct tgttatctgc tgccattggg cgttcacctt gaagaacgtg
    13861 gatatcaacg gctggttggt tgtctgctgc tgttgagaag acttgtgatt tagatgttgg
    13921 gattgtagtg ttgcgatcga taagttttgt aaatactcca cccattgttt cgataccaag
    13981 tgacaatggc gttacatcaa gaaggacaac gtccttgaca tcaccagtaa tcacaccacc
    14041 ttggatagcc gcacccatag caactacttc atcagggttt actgatttgt ttggttcttt
    14101 accagtttca gctttaacag cttcaacaac ggcagggata cgagttgaac caccaacaag
    14161 gataacttcg tcgatttctg acaagctcaa acctgcatct gaaagggctt gacgaactgg
    14221 aacttttgta cgttcaacaa ggtcacgagt caaatcgtca aatttcgcac gagtcaaagt
    14281 catttccaag tgaagaggtc cagcttcacc tgcagtgata aatggcaagc tgatttgtgt
    14341 tgaagttaca ccagaaaggt ctttcttcgc tttttcagcc gcatctttca aacgttgcat
    14401 tgccatcttg tcagtagaca agtcgatacc gttttctttc ttgaattctg ctaccaagtg
    14461 gtcaatgatt ttttggtcaa agtcgtcacc accaagtttg ttgtcccctg cagttgacaa
    14521 tacgtcgaag acaccgtcac ccaattcaag gatagagacg tcgaatgtac caccaccaag
    14581 gtcaaatacc aagatttttt cttctttgtc agtcttgtcc aaaccataag caagagctgc
    14641 tgcagttggt tcgttaacaa tacgttctac ttcaagacca gcaattttac cagcgtcttt
    14701 tgttgcttga cgttgagcgt cgttgaagta agccggaact gtgataacag ctttggttac
    14761 tttctcacca aggtagtctt cagcgtagcc tttcaagtat tgaaggatca tagctgagat
    14821 ttcttgtgga gtgtattctt ttccatttgc agaaactttt tcagaagttc ccatcttaga
    14881 tttgatagag ataactgtat ctgggtttgt gactgcttga cgttttgcag catcaccaac
    14941 gatgatttct ccgtttttga atgagactac agatggagtt gtgcggtttc cttctgggtt
    15001 tgcgatgatt ttgctttcag ttccttcaag aactgcaact gctgagtttg ttgtacctaa
    15061 gtcaataccg ataattttag acatgtgttt ttctccttgt tagttaattt tctatttttc
    15121 tttttgatac tcttcttaag tggcgacgcc gtcagagctt gacttcgtca gtctctttga
    15181 ctaaactttg agcctaaggt ctcaaaattt gcgcaaatag cgccacggcg aagagtatcg
    15241 tctttggttc gcttcgctca ctattacaaa gcaaaacata ttttatcttt cttcatagtt
    15301 tattgtcgtt tcggacaagt tttctattat gtaaattgcg acacgaggag tcgaaatcga
    15361 ttttatttcg acgacgagtt agtaaggaag ctaggcaaac gccatagcaa ttgccgtttt
    15421 ctgacgagtt gctttagcta ccgtcagaat tgccgaatcg aacacgccct aagctctgag
    15481 taaaaaagat agattttctt gtgttcatcg aacacttcgt caatctccta tttttactgc
    15541 gagcttttta cgagctttgt atcttagtta tacaccacta ccattgctgg gcgtaggatg
    15601 cggtcatgga gtttgtagcc tttttgaaag acttgggcga tggtatctac tgggtgttca
    15661 tcgtctgctg ggagagtttg gatggccata tggtagttat ggtcaaattc gccatctgct
    15721 gcgatttctt caattccttc ttctttcaaa gcgtgaatca agctttcttg caccatcccc
    15781 aagcccttct tcacatcatc tgtcaaacct tcaactgcaa gtgcacgctc aaggttgtca
    15841 agagatggta agattgcttt tgccaagtcc tggctacgat aacgttgcaa gttttgacgt
    15901 tcttcattgg cacggcgttg gatattttgc atttctgcat gagcgcgaag atatttgttt
    15961 tcgaactcat ctgcacgttc atttgccaag tccaacttag acttttcagg agttgtttct
    16021 tcagctgttt ccacaacttc ctcttcttga acttcttcta cttcttcatt ttttatatct
    16081 tgggccatgt tcgcctcctt taatgatttc aatcttaatg tacttcgtaa tgattactgc
    16141 tgaggtagcg gtaaaaatct gtcaacttca tagtcaaaac acggttgacc acattgactt
    16201 gattgattag ctgttggtaa tccagattaa ctggaccgat aatggctaga attccaactc
    16261 ctcgataagg aatgaggaac ttactactaa tcaccgctag gtcagctaaa caggactctt
    16321 gaccgtctgc aacacgaaca ttttgcatct gatcctcacg caacccctca cgaatctcca
    16381 aggccacctt ttgcggttgg tcaaagaact gataggcttc tagattggca aaattcaaga
    16441 gattgacctt gcccgccatc acaatgtttt cgttgaacat ttccttaaag atgtgttcaa
    16501 agagatcgat gacattatcc gttgttgtaa agtaacgctg gataatctgc ggaatctccg
    16561 tccgaatctt gtagtgaata tctaaaacgg tgtgaccgag gaaacgttcc tgaatgatgc
    16621 tcttcagttt cagcaaatcc tcctgcaaga agttccttgg aatcagaaac tgactagtaa
    16681 ccgttcgcga ctcgtctagg gtaaataccg ccaaggctgt atgttgcccc aaaacaacga
    16741 tatcaaaggc tgtcaaacgt tgcctgctcg gctcaacatc cagtgccact accgtacagc
    16801 cactcaggtc tgttagcaag ttagcagcct cttgcagaat atcctccaat ttgaagaatt
    16861 cctgatcaaa ggctttgaca atctcatata cctcattttc agccagccgg tgaaaatcca
    16921 gtgagtgttt cacatagtac tgaaaaccag caacacttgg catccgaccg cttgaagtat
    16981 gagccttctc aagcaaccct tgtttttcta gttccgccat gtcattacga atggttgcac
    17041 tgctagagtt aatagactct tgcaaggctt ttgatccgac aggttcgtgc gttttggtaa
    17101 agatgtcaat aatcagattt aaaatatcct gctgacgctc tgtaaccatc tcatcactcc
    17161 tctctgtctg atcaattagc actcaatgca tccaagtgct aacttatgat tctattatac
    17221 acccttaaaa gagaatgtca agacaaaaac tcaaaaaatt agcactcttt tatcaagagt
    17281 gctaaaaatc aatctgaaga cctagaacct tgctattcat ctactcggta tttccttttt
    17341 agtctgaaat aaccatgaat tagataagaa atcagaaaag catataaaac aaaaataaga
    17401 aagaaagaca tagaaagatc ctctctaaac aaactcgtac aaacaacaag accacctaag
    17461 aaagtagttg tacaggaacg aagtctagat cgcataactt cccatttgag ccccttactc
    17521 atatagactt gatcctctgg aagtaaatca gaagacgatt tacgaagaat cgaacaagaa
    17581 cctgctccta tcaattccca acctctatct ctaaaatctt gcagttcatg cttatatttt
    17641 ttaagaaatc tagaatcata gatacggtag atgacatcgt ctggttgaca ttggtcaaaa
    17701 tagaacaaac caaaacgact cgttctatac ctccaacctt tcaaatgcat ctcatgtaaa
    17761 tattcttctt acttgtccaa atcaacaatg gtgaaaatcc gaaattctac tctgctattc
    17821 attgtcttac cccaaaatta gaaaacatgc ctggcgttat ttattagata attctttcca
    17881 cttttgactc aatctccaaa aaatataaga aatctgaatc gcaaaaacta tcaataaaac
    17941 ccaatctatt atgaaagtca aaaacacttt ccaactgaaa gaactacctc cagtgacaaa
    18001 ctttgagaaa aacggtagta gagctaaaaa gagaagtaaa ataggaagca tccgcattgt
    18061 taaaatccgt ttggcataaa aaaatcttta tttaaactaa aatattatat caaaatttac
    18121 gccagttttt gaacggctga tgtagatatt ttatactttc aaaatgttta aatgtgatta
    18181 tttatttttg aaaaatagct caccagcccg actgaaagtg cttatagaat gataataagt
    18241 cgcctgccga aaacagcgga aaatagcggt gttatgcgga gataatctga cgcgatgcga
    18301 aagtatattg catacttatt ttcaacaatt tagcagagta tttttataag tgtgatataa
    18361 tagaagtata atttgttctg atagtgtttc ttatgtgctt caagtatata aaaaggcgta
    18421 aaaatacgcc tatagataat ggggttgaaa taggtttatt gttgatgaga ttgtagataa
    18481 ttcaattttt tacttccaat cgaatattca aagcctccac cttttctgcc tgtaattgtt
    18541 catcataaaa ttcaatatct tcaggatttt ccccttgaca acctcggcag aaatattctt
    18601 ccgctcgatc aggattcaaa aatcgacaag cacaaacaaa acagtcgcca tcatcattta
    18661 ttgagataat atagtagatt gaaataagat gtaaacaaat cgattaggaa agttaaatta
    18721 atttctagaa atttttagca gatgtagtgt actattctag tctcaattta ctatggcttc
    18781 aaatatatct ttcgaaaaaa tatttacaga tgtgtaattt tgaagcttgc aaaagttagt
    18841 aaacttgtag atttcgattt gaagtaactt gttttcttgc ccgatattgt ttttgaaatt
    18901 gaatttttcc atagtgactc cttgattttc ttctacacgt ctgatgataa atctaattcg
    18961 caaaagagtc aagaggattt ttcgaaaaat aaatagcgac cgaaatcgct attttaaggg
    19021 ttataggtat ttgatggctt agactgctgt gtgactgttt acccacaggc aatctttctt
    19081 ctatattagt aaaggtctaa ataattatca atttcccatt gtgaaacgaa ggttgcataa
    19141 cttgcccatt cgattcgttt ggcttcaagg aagctagtgt agatgtgatc tccgagagca
    19201 gctttaacca cttcatcttc tgtcaaagct ttcaaagcgt tgtgaagagt tgatggaagg
    19261 tctgtaatac cagcttcctt gcgctcttct gctgtcatga tgtagatatt ttcttcgata
    19321 ggagctggtg cttcgatttt attttcaata ccatacaaac caacttccaa aagaacagcc
    19381 atagcaatgt aagggttcgc cattggatcc actgaacgca actcaagacg agttcccata
    19441 ccacgtgaag caggtacgcg cacaagtggc gaacggttac gaccagccca agcaatgtaa
    19501 acaggcgctt cataacctgg aaccaaacgt ttgtatgagt taactgttgg gttcatgatg
    19561 gcagtatagt tgtaagcatg cttgatcaaa ccgcctagga aatggtaagc tgtttctgac
    19621 aactgcattc cttttggatc atttggatca aagaaggcgt tatttccttc tgcatcaaac
    19681 aaggacatat tacagtgcat acctgagcca gcaataccaa attttggctt cgccataaat
    19741 gttgcgtaaa gtccgtgttt gcgagcaatg gttttaacaa caagtttaaa gatttgaatc
    19801 ttatcacaag cacggagaac ttcatcgtac ttaaagtcaa tctcatgctg tccaaccgca
    19861 acctcgtggt gactcgcttc tacttcaaat cccattttgg tcaagacatt cacaatctca
    19921 cgacgtgtgt tgtccgcaag gtcagtaggt gccaaatcaa agtagccacc cttgtcattc
    19981 acttcaagtg ttgggtcccc attttcatcc aacttaaata ggaagaattc tggctctgga
    20041 ccaaggttga aggatttgaa tccaacttct tccatgtgac gaagagctcg tttcaaatta
    20101 ccacgagggt cacccgcaaa tggttcacct tctgttgtat aaacatcaca gatcagacct
    20161 gcaacacttc cattttcatc tccccaaggg aagactgtcc atgtatccaa gtccgggtac
    20221 aagtacatat ccgactcatt gatacgtaca aaaccttcaa tagaagatcc atcaaacata
    20281 accttgttcg acaagacctt atctaactgt tcatctgtag caggaatttc gacgtttttc
    20341 atggttccca aaatatctga gaacataaga cgaataaagg taacattttt ttccttgact
    20401 tcacgacgaa tatctgcagc tgtgattggc ataagttttc tccttaatct atgactactt
    20461 gcggttgcct aaccgcgacc aaaaggtgac tgtactgaag caaaacgccc ctgttggagg
    20521 agttcattgt gaagtgcacg acgtacttca gtctgactaa ccgctttctt ggatttcgct
    20581 tcacgttcag catatttttt cttaatggca gcgatattat aaccttcaga gatataatct
    20641 ttgatttcaa gcagacgatc catgtcattc aaggaataca tgcgacgatt tccttcgttt
    20701 cgatcgggct tgatcaactc ttgatcttca taataacgaa tctgacgcgc cgatagatcg
    20761 gtcaacttca taacactgcc gataggaaaa acagccatat ttcggcgaaa ttctttttcc
    20821 ttcatttaca atttccttct ttctgtctat tatagtctaa aaaaagacaa acgtcaattg
    20881 ataatgttat aaaatgtaac attatttttc ttttttctct aaaaagagac gaatacgatc
    20941 aatatcgtaa tttacgataa ttgcgacaaa aactcccata aacgtttctg atacacgcac
    21001 aaacacgtac gaaattgtct caccacttgg aattgatagg gtaatgatta acatagctgc
    21061 tacaccacca ataacccctg ctttgttatt cattgctaca tttgtcataa tggttaacat
    21121 ggtgcagatt ggaacaacta ccaaggtcac ccaaaaggct tcgtggaaaa aggtatttaa
    21181 taagaagaag accaaggcat agagtccacc gatactattt cctagaatac gcgaagtccc
    21241 aaaatgaaca ctctcatcaa aactctccct caggctaaaa acggctgtca aagcaccaat
    21301 ttgaagacct ttccagccaa aaaagcaaaa aatcaagaga actagaaaaa cagcaatacc
    21361 tgttttaaag gttcgcatac caagtttgaa ctgggattta tcgaatttat attttttaaa
    21421 ataactcata atctcaactt tctatttcca ttttatcata aatcggtgat ttttatgagt
    21481 aatagttgag aggaagcgtt tttattttaa gcaaaagaaa agaggaactt tcatccctct
    21541 cttctttgat ttatttataa aatcttattt ttctgtcaag gctgcaagtc ctggaagaac
    21601 cttaccttca agaagttcca ttgatgctcc accacccgta ctaatccatg agaacttgtc
    21661 tgcacggcca aggttaatcg ctgcggcagc tgagtcacca ccaccgatga ttgatttaac
    21721 tcctggttgt ttcacgatag cgtccatcac accgattgta ccagcttgga aatctgggtt
    21781 ttcaaataca cccataggtc cgttccatac aactgttttg gcaccagtca aagcttcgtc
    21841 aaatttggcg atagattttg gaccgatgtc aagaccaagg aagccttcag aaactgcttc
    21901 accttcagtg tcacgcactt cagtgtaacc agcaaatgcg ttagcttctt ttgagtcaac
    21961 tggcaagatc aatttaccat ttgctttttc aagaagagct ttcgcaacat ccaatttgtc
    22021 ttcttctaca agtgagttac cgatttcgat accttgtgct ttgtagaatg tgtaagtcat
    22081 cccaccaccg ataaggactt tatcagcttt ttcaagcaag ttttcgataa caccgatctt
    22141 gtctgaaact tttgaaccac caaggatagc cacgaatgga cgttctggag tttcaactgc
    22201 ttcttggatg taggcaattt cgttttcaag aaggaaacca gcaactgctt tttcaacgtt
    22261 tgctgagata ccaacgttag atgcgtgtgc acggtgagct gtaccgaatg catcgtttac
    22321 gaagatacca tctccaagtg atgcccagta tttaccaagt tcaggatcgt ttttagattc
    22381 tttcttgccg tcaacatctt cgtaacgagt gttttcaacc aagagaactt gtccatcttc
    22441 aagagcgttg attgccgctt ccaattcagc accacgagtg acacctggga aaacaacatc
    22501 ttgaccaagt tttgctgcca agtcagctgc tacaggagca agtgatttgc cagctttatc
    22561 agcttcttct ttcacacgtc caaggtgaga gaaaagaatt gcacgtccac cttgttcgat
    22621 gatgtactta atagttggaa gagctgctgt gatacggtta tcgttagtga ttacgccatc
    22681 tttcaatggt acgttgaagt caacacgaac gaggactttt ttacctttca agtcaacgtc
    22741 tttaacagta agttttgcca tgttacaaaa actcctttat ttattttatt caaaactatt
    22801 atatcacact ttggaaatat aaggaaagat ttcacaagat ttttcgatat ttaatcttta
    22861 tcttctcttt tccgtctcaa ggtcaaggct aaactagcaa gaccgaggct ggctaagcct
    22921 gctattaggg cttcattagc atcagctgtt cctgtatttg gcaattgttt gcttgcttct
    22981 tctgatttaa ctgctgtatt ttgagctggt ttttcctgtg tagctactac tgctggtact
    23041 gtttttactt ttgttccaat ttcaacaatt tctggaatcg cttcttggat gacttctgtt
    23101 gaacgaagac gacgctgacc gttttcatca acttcaaaga catgtcttaa cagtccatct
    23161 cgtccctgta tgatgactcg ttgttcccca actagcatct cagcattttc atgctcttga
    23221 cgatgaaagg caaccttttc ctcttaaact tccaatttag gagccttttg ttgatcagaa
    23281 gccggttgat aagtaggttt tggaaggact ttgttttgtg gtgctggttt agcaggttgt
    23341 ggtttttcag cagattcata aacaaaggca taatgagtaa agtgtggtgc tgtaaagata
    23401 acatgactat ccgtttgttc aaaagccaat tctactgcct ctttgccttc aggtaagaaa
    23461 aatactttct taactttctt atctttttca attgggattt tcacaataga agcgtaagag
    23521 agatcaacat cttgaccttt ttcatccaaa ccttctattt caaagacatg agcatcttct
    23581 ccagcaaagt atttcttctc ttcagcactt gcttgaacac gctctacttt caaacccttg
    23641 atgacagtct tctctttatt tgagaagtgt acttcaacac ctgttttact atcagaaaag
    23701 actgctggct tgtcttcttt caataaagca accagatctt ttagactctg tttcgctgtt
    23761 gcaagctctt ctggactcaa atctactttt tcaaccaagg ccttgttttt ctcaagaagc
    23821 ggagctaggg cagaacctga aggatggttt ggtttggcag ccaagagttc ttgaacctca
    23881 cctgttaagc gatcaagctc tgtcttttct tccttaaatt tctcttgacc attcagagct
    23941 ttatgagctt ctgtcaattt attaagtcgg tcattgactt gatcttgggt gctagtttca
    24001 tggtctttca acacttgttc ggccgcttca attgctttca agaaggcttc ttttacttct
    24061 gatgaagcaa agttatagac caccttgttc ttagcagctt caacttctgc taatttttgt
    24121 ttgaggtact catcgttcaa tgctgctttt ggagatacca aaacatcaaa gctaacttca
    24181 tggccttggt aatgaagcgt caaggtttga cgaccagtct tttgagcatc gtaaccagaa
    24241 atttcaactc cctcatcagt aaaggaatgt tcttccatgg tgtcattgct ataagccact
    24301 gcaaagcgtc cttcagacaa gtctaagcta tcaccaacta ggtaatcttt tttcggttcc
    24361 tgacttactt caattcccaa aatagttttc ggacttgctt catcttggcc agtgacagtc
    24421 actgacaaat tagcatttac tggttgtccc aaatattgga gagtaagatt ctgttctccc
    24481 ttatgatgcg tatcaaaacc tgatactgat acacctgcgt gagttaggcg aatgagttcg
    24541 tcctcagttc ctccttcata ctgaactcga agaacaccac ctctaaggtc caaatcctcc
    24601 ccttcggcgt agcttgtttt cttaggtcct gtttctaggc tgactgactt gattcttctg
    24661 tcatcttttg gaacggaaac tgctaggaca ttactaattt ccttgcctgg caactgggta
    24721 cgataataaa gaagaccaga ttgatttgtc aaatccaatg gtgcacttgc taggtctcct
    24781 ccaacttcgc tcttcaaggt tgcgagcgga gtttgagaat ttggattatc ataaacggta
    24841 atagttgctc cagccggtac atctgcaaag ccaacttgta ccttgttatt gcctagagaa
    24901 cgggctgcag ccttggccat cggaatattg acactctcag tatcaagctt ttcatacatt
    24961 ttccagttat agatacgaat agccttccat ggagttccat tgtcagaagt gacaacattc
    25021 aagcgccagt cttgagcagt gattggttta tcaagagtga tatctgtcac gtgtgctttg
    25081 ttaccacgga cttccttagc tagcttccac tcaccatctg catctttata ataaaggtca
    25141 aagtctttag tgttcatcaa gccatcgtta acagactcac caccagcccc tgcatgatcc
    25201 atgacccatc taacaacggt acgtggcttg gtcaaacgaa tatccacact accactcaac
    25261 tgagctgaag accatttatc tgacaagcta gtaatggtac cgttcaacat accttcaata
    25321 ccttctccac cttcagtctt agggaaagta ctatcaataa ctgttgcacc tggaacgata
    25381 ttttcagcta gtggttttgg taggctggta tcttttacag tcatacccca atcaaaggtt
    25441 gtggttgcag cttctgaacg aactccattt ttaccgactg ctacaacctt cagttcttga
    25501 gttgtaccct gagcacttgc tgagcggcta acttttggta gataaatagt tgtagaagat
    25561 gagccagtta gtaatttcca gctgtctcca tctttttcat aaacttcata gaaatctgca
    25621 tccttgttgc ctttaaattg cacaactgct tccgcttctt gggcattttt aagagattgt
    25681 ttcactacag aaaagcttgt cggcgattgt ggctcttggt gattgtccga gatagttaat
    25741 tgtcctaggt tgaactgata atcttttaca gcacctttat gctcgaaaaa tagtttgact
    25801 gcatagatgg ttttacctgc tagtgagctg agatcaaatt cttcatttgt ccagttgtca
    25861 gaaagggtta gctctttcca tgcatctgca tcatcgaatt tgtagtctgg agttgtagag
    25921 aatgccatat aaactttaga accttttcct cccttgtggg caacacgaag tttggtcttc
    25981 tcagttactt ctaacttagt agaataaagt ctcacatcct gatctgtctt accggctaca
    26041 tcaccagaga atttaaggga atttccgcca ttataggcat ctgtaaaatc atattctgca
    26101 cgaagttttt cccctgttga agtctgccac cagcgccatg ttggaagaac acctgatact
    26161 gaacgataat tccactcaga atccttagaa accttaccat ctacgaacca ttttttacca
    26221 tgacctgtat taaaagaagt agtaaaagta ttacctaccg ctggcgtacg gtccgcaact
    26281 aggttagcaa taccatacca atctttgtca cctggttttt ggccagtagg gtctccttga
    26341 taacctgtaa agaagatatc ttcattttta tgataatctt caccagtttt tcctaaactt
    26401 gtaatggtat ctggggcaaa taaaccaaga gaaaggcgca atttcccatt ttcgtctaaa
    26461 atgtcattcc acttaacctt tgtcttgtag gaaccaccct gttgcaattc caaacctgca
    26521 aatacatcat aaggattacg accaatccag ttggcagttg caatagtgta atcattttta
    26581 gccttatccc agttaaagtt agcaaagaag ttatctgccg gaaccttatc tccttctggt
    26641 tgcatgaatt ggtagttgta ttctcccaaa ccatcttgat gataacgtcc atagttatag
    26701 gtcatggcat cgtaccaaga atacttgatt ggatggttta ccttagcagc atattccttg
    26761 ctatagagca taaactggcg catcttttct ccaagaggtt taaccaaatc tccagttgtt
    26821 tcttggttga tgaaatagcc atcatagcca taatacttgg ccatgtctac caatttacgg
    26881 gcaattggga agctaccatc tgcgtcttgc ttcaaagctt cagcaaatct ttcttgatct
    26941 gcaatactat tagaccagtt gaagaagagt gtaccgtata caggaacccc gttacggtga
    27001 cctgcatcaa taacgtcagg agttggtacg agaccttccc agaagaccat tgaatctaga
    27061 tattgccaat agtcaaaagc ataggccttg aactcttctc caccaacaga agcatggtct
    27121 tttgctttag aattggtgtt tgataaggct tgaacttttg cttccttgct agctttttca
    27181 ttgactaaat gacctgtccg acgtgaagcg aggacaacag atccgcggtt aatagcatca
    27241 tcttcacgag cacctggttc ccattttaac aattcttccc aagaattaaa tttgatttcc
    27301 tttggtttta atgttttttc tgtattttta gggacatctg gctggacttc tttttcagtc
    27361 ttattagctt ctgctgctgg tttagactca tccccttggt tagttgcttc gggctttgct
    27421 tctgtttcct tgtcagactt aggttttgct tctgcagatg gtgtttctgc aaccacctca
    27481 cttgcttttt cctctggttt agctgcgcta gctgcttctg cagtttcagt agttgcagct
    27541 tcattgcttg ctggcgaagc agtttcagat gctatcgcta ctccttctgc cttttctagc
    27601 ttgttttctc tagcatgttc cccttcattc tgcttatcag cttcattggt cgaatgctca
    27661 ctctctcctg aaacaagctc tgtattagct ccgctatttt caggaactgc agtttcttca
    27721 gccaaggctg gaccagcaaa taaaacagca ccaatcatca gcgagcaggc tcctactgat
    27781 aacttacgaa tactgtaacg acaacgtctt tcaaaaaatg gattcttcat tttctcctcc
    27841 taaaagattg attttgttgt tttcaagaaa gcgctttata ttctgtagtt ttttatcaaa
    27901 ctctagaacc atgataatca catttttatc ctaaaacatt tttagacaaa aaacaataac
    27961 tgtttgcaca aatctaaaat aaggttaaaa actcttaaaa ataatacact tatcaattat
    28021 aattttcttt tacaaacttg acattaacac ttgttagatt tacttttatc ctttaaaata
    28081 gaataggaga tattccgcga ttatttttcg gaggaaaaag aaatgtccat taattggcag
    28141 gaaattttat ttcacttttt aggtggtctg gggctattct tatatagcat caagaccatg
    28201 ggagacggtt tgcaacaagc tgctggagat cgccttcgtt tttacattga caaatatact
    28261 agtaatcctt tctttggagt tctggttggt attgggatga ctgctctaat tcagtctagt
    28321 tctggtgtaa cagttatcac agtcggcctg gtcagtgccg gtctcttaac cttacgtcag
    28381 gctatcggga ttgtcatggg tgctaatatt gggacaactg tcacatcctt tctcatcggt
    28441 tttaaattag gtaactatgc cctacctatg ctctttatcg gtgccgtctg tctctttttt
    28501 acaaaaaatc ggacagtcaa taatatcgga cgcatcctct ttggtgtcgg tggtatcttt
    28561 tttgccctca atctcatgag cggcgcaatg gctccactca aggatttaca ggtctttaag
    28621 gactatatga ttgagctaag taagaatcct gttttgggtg tctttgtcgg taccggcttg
    28681 accttgctaa ttcaagcttc ttcggctacc attgggattt tacaaaacct ctacgccggc
    28741 aatctaattg acctacaggg agctttgcca gttctatttg gtgacaatat cgggacaacc
    28801 attacagcca tcattgcctc tttaggggct aatattgcag ctaaacgggt agcaggagct
    28861 catgttgcct tcaacgttat cggaacagtc gtctgcgtta tttttctagt tccttttact
    28921 gtcctgattc attggtttga agctacgcta aatctagcac cggaaatgac catcgccttt
    28981 gctcacggaa cctttaatat taccaacacc attgtccaat ttccatttat cggagctctg
    29041 gcttactttg taaccaagat tattcctgga gaggacgagg ttgtcaaata cgaaccctta
    29101 tatcttgatg aacatttcat caaacaggcc ccatctatcg ctctaggaaa tgctaagaaa
    29161 gagctcttgc acttaggaaa ctacgctgct aaagcctttg acctttccta taagtacatc
    29221 attgatttgg atgaaaaagt tgctgaaaaa gggcataaaa ccgaagaagc aattaacacc
    29281 atcgatgagc aattaacacg ttatctcatt gccctttcaa gcgaagctct cagccaaaaa
    29341 gaaagtgaag tgcttaccaa tatccttgat tcctcccgtg atttggaacg gattggagac
    29401 cacacggagg ctctactcaa tctgactgac tatcttcaac ggaaaaatgt tgaattttct
    29461 gatgccgcct tgaaagaatt agaggaagtt taccgccaaa ctagtgactt tatcaaagat
    29521 gctctggata gtgtggaaaa caatgatatt gaaaaagcac gcagtcttgt agaacgtcat
    29581 gaagcaatca ataagataga acgtgttctc agaaaaaccc acatcaaacg cctcaacaaa
    29641 ggcgaatgtt caacacaagc tggggtcaac tttatcgaca tcatctcaca ctacactcgt
    29701 gtatcagacc acgctatgaa ccttgctgaa aaggtttttg cagaacaaat ctaagaacca
    29761 agaagctatc catcataatt ggatggcttt ttactttttc ctaagcaaga ctaggctgaa
    29821 tgaaactgaa agagtattct gcagatatat agtatattga aactagaata gtacacctct
    29881 atttctaaaa cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgttattat
    29941 ttcattttac tatagtggat taaattaaaa aagtataatg tattgaatct ataacagtac
    30001 atcttgactg ctaaaatatt tctataaatt aatttgactt ttctgataga gatgttcaca
    30061 tcttatttca attcactata caatccagtt cctaaaactt tgctagaaat tgatttggct
    30121 ttccgaatta atttgttcaa attttatttc atttcaatat actgataaat ccattcacta
    30181 gcacagggca agagggagtc gctattgatt tcaacggtag caggtacata cagaggaccc
    30241 ctacctcaga tatactgcaa tatcatcgta tgcaaaaaac ctctgagatt tttctcaaag
    30301 gttctgattt tgctaattgc tgttctcaac cgctgcagta acaaaggcag tgtagagttc
    30361 ttctggtcgg tttggacggc ttgacagttc agggtgatac tgacaagcta caaagaattt
    30421 attttcagga atttccacga tttctaccaa acgattgtct ggagaaactc ctgaaaagac
    30481 aaaacctgct gcctcaaact gctcacggaa ggcattatta aactcataac ggtgacggtg
    30541 acggcgttgc accacttctt gattgtgata agcagcagca gccttagagc cacgtttcaa
    30601 cttagacgga taaagtccca aacgaagggt tccacccata tcctcaatat caatctgatc
    30661 acgcatgata tcaatgatag ggtattttgt ttctggtgca agctctgcag aattggcacc
    30721 ttcaagacct aaaacgtgac gagcaaactc gatacatgtc aactgcattc ccaagcagac
    30781 tcccaacatt ggaacatcat tttcacgcgc atagcggatg gcttggattt tcccttctgt
    30841 accacgttga ccaaaaccac ctggtacgat gatcccgtcc gcatcagaca agagttctgc
    30901 tacattctct gctgtcacat cattggcatt gacccaattg attttaactt ctacatcatt
    30961 gacatagcca gagtgtttca aggcttcgac cactgagata taggcatctt gcaactccac
    31021 atacttacca acaagggaaa tcttaacttg tttcttgagg ttcatgacct tgtccaccat
    31081 ggctgaccat tctgtcatat ccgctgctgg tgcgtctaat ttcaaatgat cacaaacaat
    31141 ttggtccatc ccttgtgcct gcaagttcag tggaatttgg taaaggtgtt caacatccaa
    31201 cgattcgata acggcttctg gtgccacatc acagaactgg gccagtttat ttttaattcc
    31261 ttgaccagct ggctcttctg tacgaataac caacatattt ggttggattc ccaagccacg
    31321 caattctttg acagagtgtt gggttggttt ggttttcatt tcaccagcag ccttgaggta
    31381 aggaagcaag gttgtatgga tatacatgac attatccgca cccacatctg ccttcatctg
    31441 acgaagagcc tctaggaatg gcaaggactc gatatctcct actgttccac caacctctgt
    31501 gataatgaca tcagagtcgg tcgttagagc ggcacgcttg attttttctt tcaaagcatc
    31561 tgtgatatga ggaatgactt gaacagttgc cccaaggtat tctccacggc gttctttacg
    31621 aagaacttca ctgtaaattt tcccagttgt cacgttggaa tatttgttga gattgatatc
    31681 gatgaaacgt tcatagtgac ccaagtccaa atctgtctca gctccgtcat ctgtcacaaa
    31741 aacttccccg tgctggtaag gactcatggt tcccggatca atattgatat aagggtcaaa
    31801 cttttgaatg gttactttga gaccacgatt tttcaagaga cggcctagac tcgctgccac
    31861 aatccctttc ccaatagacg ataccacacc accagttaca aaaatatatt tcgtagacat
    31921 agattcctct ttctaaaatg ctcaaggtct tgttaactac gaggggatat agaaaacaag
    31981 accctactaa taagaataat ctgggacgac tgcaccagat tcacagctaa tactcttcga
    32041 aaatctcttc aaaccgcgtc aacgtcgcct tgccgtagat atgtgttcct gactttgtca
    32101 gtcttatcta caacctcaaa atagtgtttt gagcagccta cggctagttt cctagcttgc
    32161 tctttgattt tcattgagta taaaatacaa gaagataact tcttgaaaaa acaaaaatag
    32221 ctccctaaga actagggagc cccgacctct aaaagaggtg cccaaacaat atgataccta
    32281 aaaataggat aattgtcaat agctaactct tattcctcgc tggtttcagc gtcgtcatct
    32341 gaaaactcgt cgtcgtcttc gttgagatcc acatcttctc ccaagtcatc tggagcgatt
    32401 tcgttgattt ctgcatcata agcttccact tcattttttt catcatctgg attttcatca
    32461 tcgtatgaaa gagctggatc tgcttcgtat gcatcttcgt cttctggatc atctgcattg
    32521 tagtcaatgg catctgaatc accatccata aaggcattga cacgtttttt cttagctttt
    32581 ggtgctactt catcgtcgtc attttcttca agagcgatga tttcttcgtc gatttcgtcc
    32641 acaccatacc atgaacgaag accccatttg ttgtccccaa gtgagatgaa gctaccgtca
    32701 aagttcaact ctgtgtagaa caaaggcaaa gcttcgcgga tatcgctgtt tgatgttcca
    32761 aggtagtttt gaatttcgtt tacaagatcg ctaaaatgca tctcatgatc gcgaccacga
    32821 agttccaaga tagcacgcgc tacctcaatc atagatagtt cacttttttc ttgcccagca
    32881 aatacttcta attccaaagc gtttctcctc atttatacta ctatcgccag agcgaacaga
    32941 ctctgacctc attttatcat ttactcttta ttttacgata attttgcaga atagtcaaag
    33001 gttaaggggg agaaaatggc aggattagac taattccaat ataaaactca ttcctttttc
    33061 tgttgctcca ttttccacaa atccaagcga cttgaaacac ctcctagaag catgattgta
    33121 ggtgtagatt tccttgaccc tcaattcttt ccatcctttt actcgagcca attcaatcaa
    33181 agcacttaga atcttttttc caagtcctcg atgttggtaa gcggaattcc caatcacaat
    33241 ggggagatta tcctgagata gtgtaatatc cccaattgga aaccattctc ccttctcctt
    33301 gacttcaatc caaaaaagct caccatgccg atccaaatag gaatacatgg cttccaaggt
    33361 cgcttgactg taaggaagct tcaccccatc tacgaggtaa accaagttca catcctgata
    33421 ccaagcaaaa gcttcctcac aatgattgac cttataataa ggaacaaaac acaatgcact
    33481 accttttcaa caaaagagtt gctgcttgat taaaaccatc acaccagtta taccattttg
    33541 cttcataccc atcttgagct aggatacgat cttctaaatc aaaaacagag taaatctttc
    33601 tttcctcgca agcttgcgca tagagatgat atagttcatc accaccatct ctatcccact
    33661 cagcagaaat cgtatcccga tctgccaata aagtctgata agccctgtga tgcccatctg
    33721 taatcagcaa acaatctcca aaggcaagaa tactgattgg atcgacttgg attgtttctg
    33781 ccgactggta aagcatctga atatcttgca acttcttttc tgataaatat agttgagtcg
    33841 gatgaagatc tgctatgttg actttcattt ctttctcctc aagggaattc gatactcact
    33901 tctgtttgcc tttaaatcgc cattggaagc ggagcttgtc atagaaggga aactcgataa
    33961 acaggactcc caagcccaca cagagactgg caaggacgtc tgatgggtaa tgaactccca
    34021 gatagactct tgataccagc acactgacta ggtagaggcc aaggacgatt tgtacgattt
    34081 ttctccagac tggatcttta atccgctgac taagaataac aatcaaagta cctaccatca
    34141 aggttacagc cagagaatgc ccacttggga aggaaaatcc cttctcctcc accagatgta
    34201 agatatctgg ccgtgggcgc tggtagatat ttttaaaggt cacgattaaa agacctgcca
    34261 aagccagatt tcccagcatg aagaaacttt ctatcttcca tcgcttacga taaaagacaa
    34321 aagctgtaat gacaacccaa gtgataatca ctgggatatc aatcagacgt gtgagggctc
    34381 gaaaaagaat agtcaaataa tctggtaagt ctcctcgaat ggcagtctga atcgattggt
    34441 caaaattgac cagcgtttca gggtaaaatt tgaccatgta gccaagaata acgaaaagta
    34501 aaagggcaaa actgcccttc attaaaaatg tttgtttatc tctcataatg ttttaaggtt
    34561 ggtttcaaga gaacatacaa caaccagaat gaaacggaaa agataacacc ttcaatcaag
    34621 ttaaaaggta ataccatggt cattaggtag ttggaaagtc ccaaaatttt tccaatatca
    34681 aagttagcaa acttagcgta caaaggaaca gcataaacat agttgagaac caacatggcc
    34741 aaggttaaac caatagttcc agctagagag cctagtagga aacgaagggt tgtccgttcc
    34801 tttttccaaa tcaaagcaaa tacgatgaca aaaactccca aagctacgat attcatcggc
    34861 aaaccaatgt aagtattcac tccttggctg ttaagaagca acttcaagag tgagcgaagc
    34921 aagagcactc ctagagcagc aggcaaatcc atgaccacca gacccacaag gactggcaag
    34981 atactaaatt cgatcttgag gaaagatgcc gctggtaaaa gcggaaaatc aaagtacatc
    35041 agcacaaatg agatggctga tagaattgca atggtcgaaa gtcgacgtgt gtttgtcata
    35101 acaggttcct ccaattttct ataaaatcag aagaagttgg aaaggattcc tctatctatt
    35161 ctcacttttt atatcccaaa agttccctct tactctatta aagaaaaaca aagcaagtgg
    35221 ttacaatccg gctataaatc tatcaaaaca gacaaagcta ttctttcgtc ttctcccatc
    35281 cagactatac tgtcggttgt ggaatctcac cacatcagct tgcgctcgcg gacttcttta
    35341 aagagaaaga aatagagatt tttcttttag actaggcgac aagctgtagg cataacttct
    35401 ggttaggcaa agcttgtcaa caaagtataa aaggaaaaga tcatttccta gttaaagtca
    35461 ccgccggtcg ggaatcacac cctgccctga agactctttt atcataacaa aaaacgcttg
    35521 caagcgcaag cattttgttc attttcattt tttatttcaa tttatccact tcataggtat
    35581 ggacgagctc aagacctgca aagttctgct ggcgaagagc ctcatagaca atcatgcaga
    35641 cggtattaga cacattgaga ctgcggacat gttcatcatt catgggaata cggagagcct
    35701 tctcaggatg ttctcgcata aaatcttcag gtaagccctt gtcttcacgt ccaaagagaa
    35761 aataatggtc ctcgtcagtc gataaatcca cctcagaata gattttttcc gcgaatttcg
    35821 aaatcagata gagttttccc ttcatctgag atatgaaatc ttctaaactc tcgtaaaaat
    35881 aaatctctag cttatcccag taatccaatc cagcccgctt catcttgcgg tcatcaatag
    35941 gaaagcccat aggcttgatg atgtggaggg gagaattggt cgcagcgcaa gtacgcgcga
    36001 tattgcctgt attttgtgga atttgaggtt caaataatac aatgtgattt gtcatgactt
    36061 gcttcctttc accattgcaa aaaaatagcc acactgcccg gagtcaagct cagcaaacag
    36121 cgtggttaag gcatcgttaa cttacctcac aacaggtttg aagtaaatca gcgaaactac
    36181 tttcttagta taacactttc agaatcattg tcaatagaaa tgacttgatt ttttcaattt
    36241 tttcaagcta tttccaaggg ttgtaaaatc gtccctgatt ctgcaagata agtagtaaac
    36301 taactactaa aaacaaggtt gccaagagca aggtaatata gtctcctttt ttcaaggcct
    36361 gataactata ccatgtgcgt tttttctctt tcccaaagcg gcgaagctcc atggcagtcg
    36421 caatggtatc aatgcgttct agcgagctaa aaatcaaggg cgtaataatg agcagattgc
    36481 ctttgattcg ttgcataaga gaagctttct tggataattc catcccacgc gcctcctgag
    36541 acatcttgat agtaaagaat tcttcctgca aatctggaat atagcgcaag gtcaggctga
    36601 cagaataagc aatcttatag ggcacaccaa tttgatttaa actggaagca aactgactag
    36661 gatgggttgt catcaaaaag ataatagcca gaggaatggt gcaaagatac ttaatggcca
    36721 aatttagcag ataaaagagc tcctggctgg ttagagtgta gacaccgatt ccctgccaaa
    36781 tcacacttct ctctccataa agtccaaccc catactcggg agaaaagaga tagaccatca
    36841 aaacgtttaa aacggcaaat accgtcgcaa aaacggctac aaaggaaaca tctttaaagc
    36901 gaatttctga taaatagagg agaaagactg aaaagatggc aatcagcaag agcattctgg
    36961 tatcatagct aatcatggcc gccaatgata ccagaatgaa aaagagaagt ttcccagctc
    37021 ctgacaagcg atgaatcaca gtatctctat gctggtaacc gattaattta gcttgcatcc
    37081 ctctctcctt tctttgtaaa atgccgttaa atccagtgga tccacatcta gtttcttagc
    37141 caagttaaag atggaggttt cttttagatt ggcttttact aacagctcag gatcgctcaa
    37201 cagactggct ggaacagtat cggcaatcaa ttctccatcc accatgacaa ggacccggtc
    37261 tgaataatcc agcatcaatt gcatatcatg ggtaatcatg acaatggtat gccctttttg
    37321 atgtaactct tcgagaaatt ccataatctc agtatagttc ttctgatctt gacctgcagt
    37381 cggttcatct aggagaataa tttcagctcc taagaccaaa attgaagcaa tggtgacacg
    37441 ttttttctga ccaaatgaca gggcagaaat aggccaatta cggaattcat aaagtccaca
    37501 gattttcaag gtttcataga ctctcgtttc aatttccttc tcatccacac ctcgcaaacg
    37561 gagccctaga gccacctcat caaaaatcat attggttgaa atcatttgat taggattttg
    37621 tagcacatag cctactcgtt ccgcccgctc tgcaacagaa tcgcctttta tatcctgttt
    37681 ttcccaaaga tagcgtcctt ccgtctgaat aaagctactt atagccttgg ctagagttga
    37741 tttccctgct ccattttttc cgacaatagc aatcttttca ccctttttaa tatctaaatg
    37801 tagggatttt aaaatcggtc tatcatcata agagaaagac acgtcctcta atttaaagag
    37861 tgactgcaat tctggagttt cttttgccag ttcattctgc agctgaacct gaccttttga
    37921 gatagacatg ttatccagat tcgctaactg ttcttccttg actaagtcca cacctaattg
    37981 acggagagtc gttagataaa ggggttctcg aattccattt tgagtcaata aatcagtcgc
    38041 aagcaactgg tcagggctcc cattaaaaag gatacgacca tcgtttatca agacaatccg
    38101 atccacaggg cgatgcagaa catcctccaa acggtgctcg ataatcagag tcgtcgtccc
    38161 ctcttcctta tgaatctggt caatcaattc gataatatcc tgacctgact tgggatctag
    38221 attggcgagt ggctcatcaa acaagagaat cggactttca tcaatcaaga caccagccag
    38281 actgactcgc tgcttttgtc cacctgacaa atcctgagga cgctgatcca gtaaaggaag
    38341 aaggtccagc ttttcagccc atttataaac acgacctttc atctcatcta gggctgtcac
    38401 atcattttcc agagcaaacg ccaaatcttc tgccacagac aagccaataa actgcccatc
    38461 tgtatcctgc aaaactgtgc taaccagatg agacttatca tagatgctca tatcaaaggc
    38521 tacttgaccc tttatcaaaa attctccata tgtctgaccc ttgtaaatat tgggaataat
    38581 cccattcaaa cactgaccca aggtagattt acctgaccca gatggtccaa caattaagac
    38641 tttctctccc ttgtaaatgg tcaagtctat cccttgcaag gtcggttctt gttgtgtttc
    38701 ataccggaaa gagaaatcct tccactcaat tatagcttct ttcatcttac tctcttcatt
    38761 cgcttcttag acttctattt tatcataaat caagcccttc ttgcagtctc tcctcttaaa
    38821 atcttagcgc caaaaagatt cctatcctag cttacttacc taactaatct ataaacatcg
    38881 aaaaagacta gttgcccagc cttccccatc attttatact cttcgaaaat ctcttcaaac
    38941 cacgtcagct tcgccttgcc gtaggtatgg ttactgactt cgtcagtttc atctacaacc
    39001 tcaaaaccat gttttgagct gacttcgtca gttctatcca caatctcaaa acactgtttt
    39061 gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta ttagtccttt
    39121 ttcaaacttc ctgcacgagt ttgggttcct gcataggcaa gtaagagaag agttcctgca
    39181 atagctacag atacaccatt ggcaattccc gcaacaatcc cttgtgcaaa tactttttct
    39241 gccgcttctt gataaatcac aacatctcca agtggtgcca agacacccca aacaagggca
    39301 tttgcaagta gttgaatgag gttaaaaata agaatatctt tccagtcaaa aacaccattg
    39361 atcactcgaa cgtactttct aaaaagtccc acaactagac caaagagtcc gctagcgata
    39421 atccaagtcc accatagacc ataaccagca agagagtcct tgattgcatg accaatcaac
    39481 ccgacaagca aaccgataat cggtccaaaa ataatagaaa gtagcgcttg taccgcatac
    39541 tgaagctgga tgcttgtatt tggaacaggg gttggaatgt tgatcatccc gatgacgaca
    39601 aagagggcag cgccaattcc gacagcaaca acttgtttaa ttgtaaattt gatttccata
    39661 ctattctcct attttatcct tctattttct ttatttcaat ggtccaagat gaaccgacac
    39721 ctacattata ggccttggca aaggaacctt ggttgatagc caaacctaaa cgatagagag
    39781 agttgatgta aaggatgggt tgcccaattc tcacatctgc aaatgatttg ccatagacaa
    39841 cctgattttg atagaccagc atatcagcat gatagatggt cacttcaaaa cgatcaccaa
    39901 attctggttc cagcttgtaa aattcttccc gtgtgataga ggtccaaagc gaaccgaaac
    39961 gcacatccag aatatcaatg gctcccttca ccagatgatc ttctatgatg gtcgctacga
    40021 ctggaagctc tacaatctgt tccacactga gctctggccc tacttcctca aaagtaatgt
    40081 gaccactggc cagtttagca ccagtatagg catagacatc acgaccgtgg aaggtataag
    40141 aatgctctgt gttttgacgc ctattggcca cctcagaaat ctcacgaatg gctacaatgc
    40201 caacgtgttt cttgataaag gaaagcgtcc cattatctgg cgtgacaatg tattgatttt
    40261 ttgcagtctt ggcaactaca ctcttacgtt tcgaaccgac acctggatcg acaaccgata
    40321 caaacgtcgt tccctcaggc cagtaatcca ccgtctgaaa gagacgatag ctcccctcaa
    40381 aaatattata aggcgtgata tcgtgcgtca agtgatggat ttttaaggtt ggagactctt
    40441 ctaaagccac tccaatcata gccgataccg caccatcaac cagaccaaag tctgattgta
    40501 ataccagtaa attattattc attttatctc cttgtatatc ctttatcata ccatatttca
    40561 gagaaagtcg ctaatagcta tttcaattgg ttagggtata gttttacctt atagcaaatt
    40621 tcctactaaa agttcttgtt attagctagt aggtgcattt tttcttgaaa aagggtatga
    40681 tagttacatc atgaaaaagt aggttttatt atgaaaatta tccttgtcgg agggggaaaa
    40741 gttggttttg ccctctgtcg ctccttggtt gcagaaaagc atgatgtttt gctgattgag
    40801 caagacgaag ctgttctcaa tcatattgtc agtcgctttg atatcattgg tatccttggt
    40861 aatggggccg attttgccat tcttgagcaa gccagcgtcc aagattgtga tatctttatc
    40921 gccctgactg agcacgatga agtcaacatg attgcagcag ttctagccaa gaaaatggga
    40981 gctaaagaaa ctatcgttcg ggtgcggaac cctgaatatt ctaactctta tttcaaggaa
    41041 aagaatattc tcggtttttc tcttatcgtt aatcctgagc tcttggctgc ccgcgctatc
    41101 gcgaatatca ttgacttccc caacgccctg tctgtcgaac gctttgctgg tggacgcgtt
    41161 agcctcatgg aatttgtcgt caagtccacc agcggtcttt gccaaatgcc catttctgat
    41221 tttcgtaaaa aatttggtaa tgtcattgtc tgtgcgatag agagggatca tcaaattatc
    41281 attccaagcg gtgacatgac tgtacaggat aaagatagaa tctttgtcac tggtaaccgt
    41341 gtcgatatga tactcttcca taattatttt aaatcacgcg ccgtgaagag ccttctcatc
    41401 gttggggcag gtagaattgc ctattatcta cttggtattc tcaaagatag tcgtatcgat
    41461 acaaaagtca ttgaaatcaa tcctgaaatc gccagcttct ttagcgagaa attcccaaat
    41521 ctctacatcg ttcaaggaga tggaaccgca aaagatatcc tgctggaaga aagtgctcaa
    41581 cactatgatg ccgttgcgac tctaacaggt gtcgatgagg aaaatctgat tacatctatg
    41641 ttccttgaca gggtaggtgt acagaaaaat attactaagg tcaatcgtac cagtctcctc
    41701 gagattatca atgcgcctga tttttcaagt atcatcacac ctaaaagcat cgctgtagat
    41761 acgattatgc actttattcg tggtcgagtt aatgcccagt attcagacct tcaagccatg
    41821 caccatctag ccaatggcca aattgaaacc ctgcaattcc atatcaagga agccaataaa
    41881 atgactgcca aacctctttc tcaactgaaa ttgaaaaaag gggttcttat tgcagccatt
    41941 attcgaaagg gcaagactat tttcccaact ggggaggata tgttggaagt tggagacaag
    42001 ctcctagtaa caaccttgtt gccaaacatc accaagattt atgacttgat tgcgaggtaa
    42061 gaaatgaata aaagtatgat tcgttacctc ctttcaaagt tacttttgat tgaagctgtt
    42121 ctcctcttgg ttcctgtggc tatcgctgtc tattaccgtg aatcgagcca agtctttaca
    42181 gccctctttt cgaccatagg gattctcgta ttgttaggcg gttcagggag tttacagaag
    42241 ccaaaaaatc aacggattta tgccaaggag ggagtcttga tcgttgccct ctgttggatc
    42301 ctttggtctt tctttggtgg tctccccttt gtcttttctg ggcaaatccc tagcgttatt
    42361 gatgcctttt ttgaaattag ttctgggttt acaactactg gagcaagtat tttgaacgac
    42421 atttcggttc tcagccgttc cctcctcttc tggcgaagtt ttacccactt gattggaggg
    42481 atgggagtgc ttgtttttgc acttgctatt atggacaatg ccaaaaatag ccacctagag
    42541 gtgatgaagg ctgaggttcc aggtcctgtt tttggcaagg ttgtatccaa actaaaaaac
    42601 actgcccaga ttctctatct cctttatcta gctctcttct ccctctttgt catcatctat
    42661 tatctagctg gtatgcctct ctacgatagt tttgtcattg ctatggggac agcgggaact
    42721 ggaggcttta ccgtctataa cgacggaatt gcccactatg gcagctcact gattacctat
    42781 ctggtcagta tcggagttct ggtttttggg gtaaatttca acctctacta ctacctcatg
    42841 ctccgtcgca tcaaggcctt ctttggtgac gaagaacttc gggcttactt ggtcattgta
    42901 ctggtttcta caggcttgat tagcctcaac accctctacc tctacccagg gttttcaaag
    42961 agctttgaaa tgaccttctt ccaggtttcc aacatcatta caacaactgg ttttggatat
    43021 ggagatatta ccaactggcc cctcttctcc cagtttatcc tccttttcct catggcaatc
    43081 ggtggctctg ctggatcaac tgcaggtgga ctcaagatta ttcgaggcct catcctttca
    43141 aaaattgcca aaaaccaaat tttgtcaatc ctatcgcccc accgtgtttt gaccctccat
    43201 gtgaatcaaa cggtgattga taaagatacc cagcataaga ttctcaagta ctttgtcatc
    43261 tatgctatga ttttgctagc gcttatcttt attgtcagcc tagatagcaa tgattttctg
    43321 gtcgtgacca gcgctgtctt tagctgtttc aataatatcg ggcctattct aggaaccact
    43381 tctagtttct caatctttag tcccatctca aaaattctcc tatcctttgc aatgattgca
    43441 gggcgcttgg agatttaccc aatcctcctt ctctttatga agagaacttg gtctaagaga
    43501 taaaatacaa aatccctctt tttacaattg tgaaagaggg attcttatat taaaaaaggg
    43561 ggaacgtttt taaatccaag cctatctgta agcaaaatcc ttactcaaat aaaagatgga
    43621 aaaacttact acacagcttg gtaatgctcc aatacaaatt gtaaggattt acttggactc
    43681 tttgttaaat gaatatattc cattcctctg gtagcaacta tctgaatacc taatctttct
    43741 gcatccacct tcatctctct ataataactc cgaacttgtg gagccagaat aattaaatca
    43801 taaacaccca taatatcata atgagctccg tacgctcctg aattcgcaat cactctaact
    43861 tctgctaatt gagcgccctc attaattgca ttggctaatt gcgcacttgt tccagaccct
    43921 gcacaaagaa ccagtacttt caactcctta ctttttatta catctatctc accaggcatt
    43981 atttcacttg tatcctcctc taaaataata tcatttgagc ttgcaatatc tacaatctgt
    44041 agtaaatatc tcgtatttag acaatatgaa aacaagacga cttccatata ggaaaccgcc
    44101 ttctcgctat gttgagtgat ttatattaaa ataacttttc ttctagctgc attttattat
    44161 tataaaaaca ttcatcataa cccccagaac ttaaataaca atttttattc aagatacata
    44221 ctcctagaat aaactttata tgaaattctc atttttgttt ttacaattct ccttagttaa
    44281 atcttgttta atatatgttt tacatatagt atttagcgcc acatagtact gaactctctc
    44341 caaaaacggt tatgcctctt tgaatagggc gttatcacaa gaaaagcatc tccacgtttc
    44401 aacttcatat ggctcaaaaa caatcaattg atgctaaaac ctgtacctag atgtttcggt
    44461 tcataaaacc atgaaactgt aaaagtggat gaaattgata gcgatagtca aatcaagagg
    44521 catcataact ctaaaaagtc acaatatata agttcatcct cggaaaaata tcattctaat
    44581 tgttgaaatg cctacatgaa aagaaacgtc aaatgctcat gaaacaacga atacaggtat
    44641 caaaactatg acaaaacaaa tccctaaatt tactaaagac actgctcaac tttacacctg
    44701 taaatggttg ttgtataata aagttacaaa gatgtacgac cacactgttg taaatcatag
    44761 tgttcgcgaa tatattactg atagcatttc tacaaataca agtaaagaga gcggatgaga
    44821 ttcaaacgaa atatgtcagt gctttggcat tcctagcctt catatcattt aaagaattct
    44881 atagacaaaa ttttttccaa tacagacact cgtaacaact gcttcatttt tctaccaaca
    44941 tatttaggaa caggataaga tacaagagta ttaatccata gctcagttct ataccaatct
    45001 aagacaaata agctaaaaaa acgattgata ataagcaaat agattccaaa ttttctctat
    45061 ctgctcattt taataaacaa tactagtgta actatccttc cagtcagaag cttgtcaaat
    45121 cacaccgaaa attcttctaa aatttatctc gttaggcaat caagcaaaaa ctcgacgata
    45181 gtacaaacat tatcatacag gattgacttc ctaaattata tactttagta aggttttcgg
    45241 ataagaaaaa aggttcattt tacatttcta aacattcttt tctaagatga aaaacagaat
    45301 ttttcgattg tgatttaaag caacaagaag attttcagta tcatcctata gatacgagct
    45361 aattaagaaa aactacattt ttgaatataa actacaataa tataaactaa attttatagg
    45421 aggaagacaa tggattggta cgattatatg atacaggcat ccaaacaatc acaattcaac
    45481 gcaagccatt ggtttcgcta tttgcgaaaa gttatttttg aagactattc ttatttaaca
    45541 aaccaagatg tagaaaagtt gctagactcc aaagaactaa cccgttttca aaaaattagc
    45601 ttgaagtatg cctttcaaga gcatactcca actcataaat atgtgatttc attaaataaa
    45661 cctgctaagt taaccaatgt tcaaaatttg atggagaaat acaaacatgg ataaaatgaa
    45721 accggtcttc caagccctaa ataaggaatt aattcaggaa aatctgactt taacaattat
    45781 ctgtgtcggt ggttatgtct tagaatatca tggtttacgt gccacacaag atgttgatgc
    45841 ttttatggct ctataatatt tgtagtgggt aaatccccta tggatattat ggagcctatt
    45901 tttgtgtaga aaaaaagtcc catatgacct ataatgaaaa gcgacaaaac aactcattag
    45961 aaagaatcat atggaacaat tacattttat cacaaaatta ctagacatta aagaccctaa
    46021 tatccagatt ttagacatca tcaataagga tacacacaag gaaatcatcg ccaaactgga
    46081 ctacgacgcc ccatcttgcc ctgagtgcgg aaaccaattg aagaaatatg actttcaaaa
    46141 accgtc
//
LOCUS       DAVDHC010000014        45613 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVDHC010000014 DAVDHC010000000
VERSION     DAVDHC010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45613
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.014"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(253..1479)
                     /locus_tag="VUR43_001097"
     CDS             complement(253..1479)
                     /locus_tag="VUR43_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5412797.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1551..2216)
                     /locus_tag="VUR43_001098"
     CDS             complement(1551..2216)
                     /locus_tag="VUR43_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5412798.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2228..2905)
                     /locus_tag="VUR43_001099"
     CDS             complement(2228..2905)
                     /locus_tag="VUR43_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5412799.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            complement(2927..3160)
                     /locus_tag="VUR43_001100"
     CDS             complement(2927..3160)
                     /locus_tag="VUR43_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412800.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            complement(3446..4309)
                     /locus_tag="VUR43_001101"
     CDS             complement(3446..4309)
                     /locus_tag="VUR43_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET5412801.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTIYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            complement(4704..5876)
                     /locus_tag="VUR43_001102"
     CDS             complement(4704..5876)
                     /locus_tag="VUR43_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET5412802.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            complement(5889..6638)
                     /locus_tag="VUR43_001103"
     CDS             complement(5889..6638)
                     /locus_tag="VUR43_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET5412803.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYESQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            complement(6650..8149)
                     /locus_tag="VUR43_001104"
     CDS             complement(6650..8149)
                     /locus_tag="VUR43_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
                     /protein_id="HET5412804.1"
                     /translation="METRNLISYSLTDIFETDKIRIELLGEIYYKNIKLELHEFAGLY
                     KIYGISLIKNITGMFLIIIFDTKTKELKIFQDITTSYFNLYYTVYGGVFYYSTSLKKV
                     MKLSHVPVTLNNKKIQEFMRNGFILDSNTLVTEINKLEYFSYISVNNTLRICGIDYND
                     SNNFTKEQVLKNWDSMLRESILRVYSEAGEANITLSSGFDSNYILYTLANYTNSSINA
                     FCIGGEKGINEIPEVTKIAKFYGINLLVDTVMSQDLEYFPDIVWRLEGSLFECGVILQ
                     YYLGRLLFQKGNTSILCGESADEIMTFKYHSVNYNQFCNDKQKSVYFSYSDYPFYVTN
                     SIVLKKNSLLLHSFGIHPRYPYKMSEIVEMSKKISDLNDKKEFHKKNCELRFQDSVLD
                     NINSVPGTTHLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNI
                     EENLEDDIERILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            complement(8217..9061)
                     /locus_tag="VUR43_001105"
                     /pseudo
     CDS             complement(8217..9061)
                     /locus_tag="VUR43_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9081..10697)
                     /locus_tag="VUR43_001106"
     CDS             complement(9081..10697)
                     /locus_tag="VUR43_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412805.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            complement(10707..11660)
                     /locus_tag="VUR43_001107"
     CDS             complement(10707..11660)
                     /locus_tag="VUR43_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5412806.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYHFGFFYCIYDNYVQLKFRK"
     gene            complement(11653..12857)
                     /locus_tag="VUR43_001108"
                     /pseudo
     CDS             complement(11653..12857)
                     /locus_tag="VUR43_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13100..13369
                     /locus_tag="VUR43_001109"
                     /pseudo
     CDS             13100..13369
                     /locus_tag="VUR43_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            13500..13851
                     /locus_tag="VUR43_001110"
                     /pseudo
     CDS             13500..13851
                     /locus_tag="VUR43_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14127..15433
                     /locus_tag="VUR43_001111"
                     /pseudo
     CDS             14127..15433
                     /locus_tag="VUR43_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(15473..16483)
                     /gene="tsaD"
                     /locus_tag="VUR43_001112"
     CDS             complement(15473..16483)
                     /gene="tsaD"
                     /locus_tag="VUR43_001112"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET5412807.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVLDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEVTDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWNLNAKPSLAFDT
                     ME"
     gene            complement(16473..16910)
                     /gene="rimI"
                     /locus_tag="VUR43_001113"
     CDS             complement(16473..16910)
                     /gene="rimI"
                     /locus_tag="VUR43_001113"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET5412808.1"
                     /translation="MIEIKRIQQRPDLAQAIYAVMIAVYPINPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(16907..17590)
                     /gene="tsaB"
                     /locus_tag="VUR43_001114"
     CDS             complement(16907..17590)
                     /gene="tsaB"
                     /locus_tag="VUR43_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET5412809.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENSKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SVESYIKRL"
     gene            17768..17953
                     /gene="cibA"
                     /locus_tag="VUR43_001115"
     CDS             17768..17953
                     /gene="cibA"
                     /locus_tag="VUR43_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET5412810.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            17955..18107
                     /gene="cibB"
                     /locus_tag="VUR43_001116"
     CDS             17955..18107
                     /gene="cibB"
                     /locus_tag="VUR43_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET5412811.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            18925..19158
                     /locus_tag="VUR43_001117"
     CDS             18925..19158
                     /locus_tag="VUR43_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET5412812.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            19160..20839
                     /locus_tag="VUR43_001118"
     CDS             19160..20839
                     /locus_tag="VUR43_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET5412813.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            20893..20985
                     /locus_tag="VUR43_001119"
                     /pseudo
     CDS             20893..20985
                     /locus_tag="VUR43_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21192..23105)
                     /gene="mnmG"
                     /locus_tag="VUR43_001120"
     CDS             complement(21192..23105)
                     /gene="mnmG"
                     /locus_tag="VUR43_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET5412814.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMR
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(23115..23570)
                     /locus_tag="VUR43_001121"
     CDS             complement(23115..23570)
                     /locus_tag="VUR43_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET5412815.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLIMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(23711..24832)
                     /gene="mnmA"
                     /locus_tag="VUR43_001122"
     CDS             complement(23711..24832)
                     /gene="mnmA"
                     /locus_tag="VUR43_001122"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET5412816.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSLLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDEAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            complement(25237..27036)
                     /gene="pspA"
                     /locus_tag="VUR43_001123"
     CDS             complement(25237..27036)
                     /gene="pspA"
                     /locus_tag="VUR43_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HET5412817.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEESPVASQSKAEK
                     DYDAAVKNAKNAKKAVEDAQKALDDAKAAQKKYDEDQKKTEEKAKEVKKASEEEQAAN
                     LKYQQELVKYIKYTRENNSTKRTEAEKVMTAAKKEHEKKQTELAKVLAKVIPSAEELE
                     NTRQKAEKAKEKEPELTKKLEEAKAKSEEAEKKATEAKQKVDAEHAKEVAPQAKIAEL
                     ENQVHRLEQDLKDINESDSEDYVKEGLRAPLQSELDTKKAKLLKLEELSGKIEELDAE
                     IAELEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAEADLKKAVDEPETPAPAPA
                     PAPAPAPAPAPTPEAPAPAPAPKPAPAPKPEKPAEKPAPAPKPETPKTGWKQENGMWY
                     FYNTDGSMATGWLQNNGSWYYLNANGAMATGWAKVNGLWYYLNSNGAMATGWAKVNGS
                     WYYLNANGAMATGWLQYNGSWYYLNASGAMATGWAKVNGSWYYLNANGSMATGWLQYN
                     GSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWF
                     KVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            complement(27322..27600)
                     /locus_tag="VUR43_001124"
     CDS             complement(27322..27600)
                     /locus_tag="VUR43_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412818.1"
                     /translation="MYNDVIERISLCEFIGDIFYSKITSCCIVAKDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSEVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            complement(27585..27824)
                     /locus_tag="VUR43_001125"
     CDS             complement(27585..27824)
                     /locus_tag="VUR43_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412819.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSANYKYLEIFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            complement(28567..29295)
                     /locus_tag="VUR43_001126"
     CDS             complement(28567..29295)
                     /locus_tag="VUR43_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412820.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            complement(29292..29645)
                     /locus_tag="VUR43_001127"
     CDS             complement(29292..29645)
                     /locus_tag="VUR43_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET5412821.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSSGT
                     FIALTGAAVLTKKLINYIKVGGLGGWLIGAAAGVLAGAAGRITYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            complement(29701..30603)
                     /locus_tag="VUR43_001128"
     CDS             complement(29701..30603)
                     /locus_tag="VUR43_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412822.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLQLNLEIPFDFVVSTSL
                     TFFVLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKINVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            complement(30811..31185)
                     /locus_tag="VUR43_001129"
     CDS             complement(30811..31185)
                     /locus_tag="VUR43_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET5412823.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAEFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            complement(31562..32539)
                     /locus_tag="VUR43_001130"
     CDS             complement(31562..32539)
                     /locus_tag="VUR43_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412824.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            complement(32853..33911)
                     /locus_tag="VUR43_001131"
     CDS             complement(32853..33911)
                     /locus_tag="VUR43_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412825.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEDGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            complement(34068..34313)
                     /locus_tag="VUR43_001132"
     CDS             complement(34068..34313)
                     /locus_tag="VUR43_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412826.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            complement(34793..35005)
                     /locus_tag="VUR43_001133"
     CDS             complement(34793..35005)
                     /locus_tag="VUR43_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412827.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(35013..35330)
                     /locus_tag="VUR43_001134"
     CDS             complement(35013..35330)
                     /locus_tag="VUR43_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412828.1"
                     /translation="MLQVKNDLGQRWAITGAITGAAYAALAAAGGGGLQLVLASYGLR
                     SALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGADWIFTNIIDGWDGRRDNQL
                     RIG"
     gene            36042..36905
                     /locus_tag="VUR43_001135"
     CDS             36042..36905
                     /locus_tag="VUR43_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412829.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVETHYQPKKL"
     gene            complement(37092..37562)
                     /locus_tag="VUR43_001136"
     CDS             complement(37092..37562)
                     /locus_tag="VUR43_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET5412830.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVAHQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(37528..38334)
                     /locus_tag="VUR43_001137"
     CDS             complement(37528..38334)
                     /locus_tag="VUR43_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET5412831.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQNGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(38541..39182)
                     /locus_tag="VUR43_001138"
     CDS             complement(38541..39182)
                     /locus_tag="VUR43_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412832.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(39179..41287)
                     /locus_tag="VUR43_001139"
     CDS             complement(39179..41287)
                     /locus_tag="VUR43_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET5412833.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(41342..41635)
                     /locus_tag="VUR43_001140"
     CDS             complement(41342..41635)
                     /locus_tag="VUR43_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET5412834.1"
                     /translation="MIGEINHEKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSG
                     NFGYSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            42043..42363
                     /locus_tag="VUR43_001141"
     CDS             42043..42363
                     /locus_tag="VUR43_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5412835.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLVICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(42415..42987)
                     /locus_tag="VUR43_001142"
     CDS             complement(42415..42987)
                     /locus_tag="VUR43_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET5412836.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            43229..43900
                     /gene="sdaAB"
                     /locus_tag="VUR43_001143"
     CDS             43229..43900
                     /gene="sdaAB"
                     /locus_tag="VUR43_001143"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET5412837.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            43909..44781
                     /gene="sdaAA"
                     /locus_tag="VUR43_001144"
     CDS             43909..44781
                     /gene="sdaAA"
                     /locus_tag="VUR43_001144"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET5412838.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            44803..45435
                     /locus_tag="VUR43_001145"
     CDS             44803..45435
                     /locus_tag="VUR43_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET5412839.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
BASE COUNT        14601 a         9396 c         7314 g        14302 t
ORIGIN      
        1 tttcgaagag tataagtagg ctgaaaagaa tccagtcaca gcatggacta ttatatagca
       61 gattgaaata agatgagaac aaatcgattg ggaaagtaaa attaatttct ataaatgttt
      121 tagcaattgt ttcatactat tttagattca gtttactata acacattcag aaaagagaaa
      181 aagtctgttg attttgacca tcataaaaag actggcaatc cagtctcaaa catatattat
      241 agaaattctc cactaaatac tttcacgaat attcagaagc ataacaaagg caactagaag
      301 aaatagcaat aaaacaaagc taactgccag agttccaaag ctagtagcaa tggttaccaa
      361 agctattgta aataagctag gtaaaacaac cgtaatggca ccgatagagg attgaactgc
      421 tcccattgac tcctcaggta tttgtttaaa aacgagttct tgcaatctag gagagagaac
      481 acctgcgaaa aaggcatcca aggtactaaa gatgagaatc cagtcaaaac gaactgtggc
      541 aaatcctact agaagaagca actggatgac aagtgaggca tagagagctg tttttatgga
      601 aatggtatgt tgcagatagc cacttacaag gcttccgaca atcagggctg acagttcaaa
      661 agtggatagc aaggcaagag attgacctgt ttgtaaattc aaaaagggtt gattcctcaa
      721 aaatagagta gagacaggaa ctgtaacatt tatcactgct tgactagtag agataataaa
      781 caaaaccaag agcaccttat tcatattcca tatcaatttc gatgattgga gcaaatgctg
      841 gcaaaaggat tttacagaga gtccttcttg atagttaatc gttttttcta ctttcaagag
      901 gtcagttttt atgaagagga tacctaaaaa tgcgattaaa aaggtaagag cgttcagcaa
      961 ggaaataaac tggatggata gaatacctaa taagactcct cctagaatat tactgattgt
     1021 tttcactaaa ctaacagttg actgtttaaa tccaatagct tctgccagat ggtcttgccc
     1081 aataattcta atgaaaatcg gagtgagcat ggcgcctgaa aaataactca acgtgtcaga
     1141 caagaggtta atcagacaaa taaatgctac taataacaag gaaaaggact gccctgaaag
     1201 tgataaagac actatagagt aaagcaaaaa ttttgcaaaa ctaatgactg tgtatttcaa
     1261 gacacgatga tgttgaaaat ccgccaaaac tcccagaaag atttgtagaa cttggggcag
     1321 ggtttctgaa atcgtgatga gtaaaatcgc caaaggggca aaagatgcat ctgccacata
     1381 attcaggaag gccagataaa aaatcgtatc cccaagcgtt gaaatccact ggttgatagt
     1441 taattgccta aaatctctat tttgaagaaa tactttcatc acaactcctt cttaagttca
     1501 aatgggaatc tttccccaag gatagaccgc gatactacta acaaccaaaa ttacagtaac
     1561 atcaaaagct gaccaatgcc attgtagact atatgcagtc caataggcca ataaattgac
     1621 tttgtcattc taaataagac tgcaaatata agacctccac ccatatagaa gacaaagtct
     1681 gtcaagaccc aaccgtgatt actaatgtgc gagaccccaa ataaaacagc ggaaccaagt
     1741 acatctagcc cccatttctt tcctttttcc agagcagtca tcactaatcc acgataaatc
     1801 atgtcttcaa aaatgggacc tgcaatcaca ggataaaaaa aatacatcaa aaatgccgta
     1861 gctcctgtaa aagtaggagc agcatgttga taagaaattt catttcgagt aggtgggaaa
     1921 agaaaaaagg tgacaaaatt ccaagcaaca aaagcaagca gagctaggaa ggaatagaaa
     1981 agataggatc ctttaaactt tctactattg attttctgcc atttccccga ccaaatcata
     2041 gcaataagag caaataaaac cacaagaaaa ttcaacatca tatccgacag ataataggca
     2101 aagtcagata gcccagcaac aaggtcgctg cgtaaaacta aaacactgaa cttctggtca
     2161 gcaataacta gtagaaaaac tataataaag tagcggtgtg agattatctt tttcatatat
     2221 cacctttcta atatccaaat accaataaag taacaatgag taagaagcta ttccatgaag
     2281 catgcagagc tatagcccaa tagatggatc gggtgtagcg aaacatcata caaaatatca
     2341 agcccattcc aaaatacttt atgaaatctg tcgttatcca accatactgc aaaacatgca
     2401 tagcgccaaa tatggcagcg gaaacaagaa catcaagata gtatctatta actttagata
     2461 aacttgtcat caaaagacca cgacaaacaa cctcttctga tacaggtgcg ataatactag
     2521 tataaagtat tcgcgtaaca aaatagctaa ttcctgttaa actggtggct acttctacga
     2581 ctgtacttcc attctgggta cgaggaaaga tataggttgt tagatttgcc cacacgaaca
     2641 ataagaaaaa agaaagaagg aaaacaccca ggtaagacca acgaaactgg aaacgaccac
     2701 actctttcca atgttcactt ttgacaaaag caattgtagc tatagttccc agaataagta
     2761 ccaataaaac ttggaacaca tagtacatat tatcagacaa agcaaccata aaatctaagt
     2821 ctgatgtgac attaaaaatg aggtaataag tcaaaatcaa caagccagtt gctaggtgaa
     2881 atttcacttc tttcattttc ttcatcctat tatctcctat aagagcctat cttctacggc
     2941 ggccaaacaa tccatctgct aaatctatag tccaatcaaa agctccacga ttaggactca
     3001 tcccttgatt gccccaacca gggtaaattc ctgggacgcc ccaaccagat ataccacttc
     3061 ttccaccacc tcccatagaa tttacgaggt tgcctcctct aacatcttgc aactcagctt
     3121 ctgtcaattc cattgtttct gcaaattgta aatttaacat cttttacact ccttcaatta
     3181 tcttcatttg taaaccactt ctgcgaccta ggatttgctt caaatgtttt acaaggacag
     3241 tataacacgg aaattggctt attttagaaa atcgcatatt tgatattttt tcttatagaa
     3301 atttcagatt tgcgattttg gtagatttga ttatttccct ggtataataa agttattact
     3361 aatgaggagg gaagtaatat gaagaaacaa gttttaacat tattgacgat cgttgctgat
     3421 attattatct ttttcccatt tctaactaat cgataagctc tttgtattgc tgcaaacgca
     3481 attcaaaaag ggctgtcaat tgtggatttt ctaatacttg cagagattgg ataaaatgtt
     3541 caatctcttt ttgattgctt cctttggttt gaagaaaaat ctgcattttc tttaaaaact
     3601 gccacaatac tttttcaaaa acatcgtatg gacggagcat gcgctccagc tcagcttcaa
     3661 agattggaat ataagaaaat agcttgcgct ccataagttc tgagatgata ttaagataac
     3721 cacttttcat ataccatcga ttgtgtacta actctttaaa ttccttggat ttttcgagta
     3781 aggaggttga taaaaagatc agatcttgat tgctcaagaa gggcatagta ttgcaaaaaa
     3841 gatagagttc aaaccaggtc caagactcaa tagcgtagag gtagatagtc aaaaactcgc
     3901 tatcctcctc tgttagcggg tagcttttat ctaaggaatg gagtgcattt ttaatcacaa
     3961 tggcattcaa acgacgatag gtctgcgcca tctgttcttg atcgacttcc tccaatagct
     4021 gctctaaagc agctatatcc tgatgggaaa agcaatccac aacccttcta ccaattcgca
     4081 tatgtggaga ttcttgatag ttgttgagtt tgtgcccaaa ctcatcaaaa ttcatattga
     4141 tcccttggat ggctaggatc agcttgtctg cagacagcat agactgtcct agttcaaact
     4201 tggacaactg agaggctgtt agtccagcac aagccacatc tgactgcttg agctttctcg
     4261 ccaagcgcaa ttccttgtaa aattccccca gttccatttt ttcaatcatc ctaccacctc
     4321 ctagcttttg catattatat cattatttgt gttcatttgt caaaacattc tgacactttg
     4381 gtgattgaaa aagccagcct taagctgact ctaaaaggac cgagccttgt acaatacaga
     4441 actcaatcct cgttctaaat agaatgtcta acttttttgg gcagtacacg agcttgggga
     4501 acagccactg gaacgatgag gtgtgagctc aaaatatcct ccagttatgt ttttcctaat
     4561 agtataccgg aagagtgaaa ggattttata atggagcggt tacaaagaac ctactttcta
     4621 ttaaacagta tactatgaaa atgtgaaaat ttaacatttt tttgtacaaa ttttataaat
     4681 tattgccttt ttaatatcaa tagttaatct cttatccaga tcccccttgt gtaaacttta
     4741 tctttataag cttcaaggcc cctatcccat ctatttgcaa caattagatc gctttgtttt
     4801 gtaaatagtt caaaattctt ttcaaaaatt acgttatcta tactaacgtt taaatttggt
     4861 tcatatacta aaatttttat accgacaatc aatagttcat taattatact taaaatagct
     4921 gactctttgt aattatctga attatatttc atccccaatt tatatattcc tactatcttt
     4981 ggctttcgtt ccaatatttg tttaactatg aactgttttc tatttgtgtt tgaaatatca
     5041 atcgcttcta tcactggggc atttatttct ataaattctt tttttaattg tttagtatct
     5101 ttgggaagac aatatcctcc aaatccaaaa gaaggattat tataaaaatt tccaattctt
     5161 ggatctaaac aaacaccttt tattacaact tcagcattta aacttctcct ctcagcaaaa
     5221 gaatctagtt cattaaaaaa agcaacacgg agagctaaga atgtgttaga aaaaagctta
     5281 attgcttctg cttcagtagg agaaactaac ataacatttt taatattggc agtactatga
     5341 gtactaatcg aaaggaacaa ctctgcaatt tttcttcctt caactgtctc atctccaaca
     5401 actatgcgac ttggatataa attatcatat atagaacaac cttctctcaa aaattcaggg
     5461 acaaaaatga tattttttgt atcaaacagc ctttttaatt tgtttgaaaa gccgatcgga
     5521 actgttgact ttaaaataat ctttccatta ggttttaccc tcagaatctt cgataccgtt
     5581 tgttcgattt catatgtatt aaaactacca attttctcat cataatctgt cggaagcgca
     5641 ataatataat aatcaatatt atttttaatt tcagaaaatg tatcaaaaaa agtaatattt
     5701 aagttattct cgcaaaaaaa cttcataagc tcttcatttt tagatggaag agtgcccttt
     5761 tttaaattat ttatttttac agaatctata tcatatgcaa caactttata tttagatgca
     5821 aatagtaacg cgtaggccag cccaacatgc cccaaaccaa ttactgctat attcataaaa
     5881 ctacttcctt atttcttaat ccaaaatcta atagaataag ctgccccatt ccttaaatac
     5941 aactctttaa tattgtttaa aagtttttca actgatttcc agattatcaa aatctgagat
     6001 tcatagcaca atattgatga tattctatca atataatgtt tttcatcaag ttcctcttga
     6061 tacattttta attctttagt ttttcccata taactaacca tactactatc acttacatat
     6121 gggaagtcct cataatatat tactttataa cgcataaatt caagcgccct tccaatacta
     6181 ttcacaaaaa catgatcaac atggtcacca agtgaaagcg gacaatatac gacacatttg
     6241 tcgtctaaat gcattaacag ctcttttatg atatcattct ttaatgtgtc ctcatttttt
     6301 aattcactat agatatgacg gtatagaaaa ttgccatttc tatctttcct atagagacat
     6361 tcatagtacg ataagtgtct aaaatcacac tgtagacgtt cacaagctaa cctgtcttct
     6421 ttcttccttt cttcaatcgg atatttccca aggttacaca acttatgaaa ttgcttagca
     6481 gagggctgta gctgttggct caaagggtaa ccagaaaata tagtaataac aagtacaatt
     6541 tctccttctg aagttaattt tgaaatataa tcaccacagg aaaaaattgc gtcatctaaa
     6601 tgtggagata aaaatatata cttagtattg ttactcataa ccattccctc tacaatttat
     6661 ctaaaaattc actaagtgtc tgattaaatt ccacatcatc aaaaaaattc accttattct
     6721 taataatgaa tatttcgtta aataaacata tatataaata tttcaatatc ctttcaatat
     6781 catcctctaa attctcctca atattttgta tcagcccatt tacaatctta ttaaaaaaga
     6841 taagctcttt atctctaaaa ttaaatattt tcatacaact gttgtatcga aaaatatata
     6901 aaataatttt tactaatgtt tgaatattta aacaactaaa taaatgagtt gtacccggga
     6961 cactatttat gttatcaaga acactatctt gaaacctcaa ctcacagttc tttttgtgaa
     7021 attctttttt atcgtttaaa tctgatattt ttttagacat ttcaacaatc tcagacattt
     7081 tatatggata tctaggatga atgccaaaac tatgcaaaag taggctattt ttctttaaaa
     7141 caattgaatt tgtaacataa aatggatagt cggaataact aaaatatact gacttctgtt
     7201 tatcattaca aaattgattg tagttcacag aatgatactt aaaagtcatt atttcatccg
     7261 ctgactcgcc acaaagaata cttgtgttcc ctttttggaa caacaacctg cctaaatagt
     7321 actgcagtat gacaccacat tcaaagagac ttccttccaa tctccatact atatcgggaa
     7381 aatattctaa atcttggctc attacagtat caactaataa atttatacca taaaattttg
     7441 caattttagt tacttcagga atctcattaa ttcctttttc tcctcctatg caaaatgcat
     7501 taattgaaga attcgtataa ttcgctaatg tatataatat ataatttgaa tcaaaaccag
     7561 atgatagtgt aatattagcc tctcctgctt cactatacac tcttaatata gattcacgta
     7621 gcatagagtc ccaattcttt aatacttgtt ctttagtaaa attgtttgaa tcattataat
     7681 caataccaca tatacgaaga gtattattta cagaaatgta agagaaatat tctaatttat
     7741 taatttcggt tactaaagta tttgaatcta aaataaatcc atttctcata aattcttgta
     7801 tttttttgtt atttaaggta acgggaacat gagataactt catcactttc tttaaagatg
     7861 tactataata gaacacacct ccataaacag tatagtataa attaaagtat gaagtcgtta
     7921 tatcttgaaa aatttttaat tcttttgtct tcgtatcaaa aattataatt aaaaacattc
     7981 cggtaatatt ctttattaag ctaattccat aaatcttata caatccagcg aattcatgca
     8041 attccaactt tatattttta taataaattt ctccaagaag ttcaattctt attttatctg
     8101 tttcaaagat atcagttaaa gaataactaa ttagattcct agtttccata tcgaagcttc
     8161 ctgtgatatt caataaagta ttttccatat ttctttatct ctctcgaata gattaactat
     8221 tctaaaaaat atttaataag tttactttta taatcttgta aaccataaca aaaagaataa
     8281 tttctatcta aaaaatgaca tctactaatc tcttctacat atacgtattt tccaatagaa
     8341 tctttcccaa acatactatc ccaccaaaaa atacaaaagt attctatatt agtaagatcg
     8401 ctataataga taattcctcc agcaacaatt tttttccaaa tagcaacgaa attgttttaa
     8461 aatttttttg attatataaa agcttaaata attcaaattg gctttcagta aacgtaaccg
     8521 aaaattttcg attgcaataa tttttccagt tttgcagtat atctgaaaca cgactgaaat
     8581 tataaacaca aacatatttt ccgttatttt tatcaaccag tgttctaaaa cgcttgtaaa
     8641 aaacaccaaa tttagagtca tctgaaacat ctacaataat aagctcttct ctatgacaca
     8701 aagatatact ttgagttttt aggatgagat ccatattttt atagcaaaaa tcgataaaat
     8761 tcttttcaat ttccaaagaa aagtgatgca gcaacgttgg atcaacttgc ttattggaaa
     8821 ctccatctaa gattgggata ttttttttag ctagaactag tagaaatata tagtcaaata
     8881 acagatacct taagggtttc tcatctacat aaaaaaatga tacttttttc ttatctaata
     8941 atttctcaca tattataaac aattcttcga cagaggaata cttaacttct aactcaatat
     9001 cattaaagta tacttttttc tcttcagtaa ttacctcata agcttcacaa tagaatctca
     9061 tgtttctctc ccctatattc ttaaataaaa tcctttggaa attgatatat cttagtaaaa
     9121 tattgtttaa gttccggatg cggagcatgg gtaacaataa tgacagtcaa atcctctcta
     9181 tctaatatct tacgttcaat cgctaacgaa gttctcctat cgatagcaga agttccctcg
     9241 tcaattaata ctattttctt atttctaatt agccctctag ctaaagtaat tttttgtttc
     9301 tgccctcctg acagtaatct cccatcatca ccaacataat aatctaaaat gttattagga
     9361 aaatctttta cactcaaacc aacttgctct aaagactgta gtatttcttc atcagtataa
     9421 ttttcttcca ataaaatatt atctctaatc gtaccttcaa acaaataagc tttttgatct
     9481 acatatagaa cattcgaaac catatttaaa taggaggttt tttttatatc atccccgcag
     9541 aatcgcaatt ctccactata atctctcaaa aagccattca ataattttaa taatgtagat
     9601 ttcccgcttc cactttcacc taaaattaaa tacttttcat tacgttgaaa acaaaaattt
     9661 aagtttttta atatttcttt atctccatac ttatagcaaa tattttttgc ttcatataac
     9721 ggaaaatctc tattcacctc atttggttcg atatcattca ttttatttga ctcaattgga
     9781 ttaattgaat acaattttaa aaaaataggc ttcgtaccaa taatagagga taattgacct
     9841 cctaattcac ctagcgctgt aaaaataaca cctgttagtg ctcctattgc ttcaatagta
     9901 ccaattttca ctattccttt tattgcaaga tagcctgtta aaaaaacgag agatatctga
     9961 aaaaaaatat tgagaaagaa gctaatagcg cctgctaacg tttctacagt tgtctttctt
    10021 tgtataacca tctttaataa aattcctgct tctttaattt tcttaggcaa tacatataaa
    10081 agattcaagg acgctaacac atcaaatcca ttcaatatag tctcactaga ttttaaaaaa
    10141 gcttcatttt ggttagttaa atttagacta acttctcgca ttttcgatgc aaagattttt
    10201 ggtacaagta gcataatcat taatgaaaac aaggtggcta cagtcaatga ccaatgatag
    10261 tgattaagag tcacaactgc aaatatagta ccagaaattc cttttattac taaaaaaagt
    10321 tgtttaaaag cctgatcatt taaagtctga acgtcattat ttagccacga aagatatgtt
    10381 cctgatgatt tactatgaaa ttcttgatag gtagagttag agatgtctgt ggcaactcta
    10441 tttcgaatct ctagattaaa ctcttggatc acttcaacct gataattttt cactacccag
    10501 tcaaggaata ttatcccaca ccagacaatc atttggtaga ttgacaattt caaaaaccgc
    10561 tctaaattca tcgcaattaa ttcattcaac accagagcat taatagttgc tgcataaatt
    10621 agcaataatt gaccagcaac aataaatatc gttaataaac taaatttttt tatatttgat
    10681 tttataatag tatacacaat agtttctcac tttctaaatt ttaattgaac atagttgtca
    10741 tatatacaat agaaaaaacc aaaatgatat aataacatat atttcaaaaa aagaaattcg
    10801 ttaaaaattt tttcttctct tgccttcttg attactttta aagccttgca tttgtctcct
    10861 attaatagta accgctttat gtttaaagaa taatatttct ttgtaaccaa tattctctcg
    10921 ttgaaactca ataaattaaa atatttccta cagtaattat aatattcttc atctgcatta
    10981 attgtttttt gtgtcactcc agtgataccg ttttctttac tgtgagcgta gtaattcacc
    11041 aagaattctc gcactatatc aatttggtat ccttgagcaa gtagttttaa taaaacaaca
    11101 ccgtcctgat gtgaatctat tttctcaaaa ccattaatta attctagcac ctctttttta
    11161 cacaaccaaa atgacgtacc tgctatattg tgaaccattt gaacaaacaa gggatttcca
    11221 acaaaatcgg tcttctcctc ttctcgtgta ccatttggat aaattattat tccataacta
    11281 taaactaaag ctaaattctt cattctactc tttttaaaac aagccatcaa ctttaaaatt
    11341 cgatctggca tatattcatc atcatcgtct aaaaatgata tatacttacc tctagaattt
    11401 ttgataccta tgtttctggc attagttgca cctaaatctt cattacttaa aattaactta
    11461 attctatgat tggtatagcc aaattgatgg ataattttat ttcttaaatt tacattacta
    11521 taattatcat caataattat aacttcgata tttttataac tttgatgtaa acaacttttc
    11581 acagctctaa tcagagattc atacctatta tgtgttggta ttataatact tactaattct
    11641 tgatctatat tcctatccat gactactctt ctctaataat tcatcatata ctctcatggt
    11701 ttctacaaac attttttgca cagaaaaatg ttttcttatt tttgatttac tattctcacc
    11761 tatatatttc aaatactcag aatcattgag taaaaaatta gcacaagcac acactccctc
    11821 aacatcttcc ttctcaaata aaaatccatc aaccctatgt tcaataattt cacttaaccc
    11881 gccaacatta ctagctaaaa ccggagttcc ttgtgacatt gactctaaaa cacacatagg
    11941 tattccttct gtatcagaag gaatatacaa taaatccgat atttggtaaa ctatagtagc
    12001 tggatagatt tcaccaagta acctgaaatt atctctacat ttcaaatggc aaattttttc
    12061 tttcaaagca gcccacatac taccatttcc agccataata aaaatcacat cttctctgac
    12121 taaaaataat ttttctgcaa attcaaggaa tctatccggc cttttttctg gatccaacct
    12181 tccaacataa caaatgattt tttgttattt ggaatacaaa attctttttt aaagtcttga
    12241 acacctacta catctaaatc gctatttgat acattaattc cgttatttat tgcaactatc
    12301 ttcttatttt ttattatact ctccaatctt tttttcatag tttcagatac acaaataaaa
    12361 gcatctccca tagaatatgt ccaaaaatca aaataagtca agaatttctt ttttaagtta
    12421 tattcaaccc atccatggca tgttatcact gtcttaacct ttccaaatcc attcttgtca
    12481 agttttttta acatatataa aaaataatta gttgagtagc catgacagtg tataagttgg
    12541 atttttaata attttaaaat atttttaacg tgtaaggcag tttcaaaatt atttgaacat
    12601 tgagtacaat caacataggc aatatctaaa tttttataat catcaataac ctttgaatct
    12661 ctagatacga ttatcaaaat aggatataga gacatccttc tgatctgctt tttacaaagt
    12721 ccaattatat gcggatctat acctccacaa tgtccattat tatacctaac tataatatga
    12781 gccgaaaaca ctatatcctt aatgtctcca tatccatcag ggatattaat atttattttt
    12841 ccacaactat attgcattgt aaccatctcc ttaaacgacg cattatgata tttgatagag
    12901 aaatttttat gaataactca ataattttat agtaaatcat gcttatatct caaagatacc
    12961 tattttctct tgtctcgacc ttctccaaag aattgctata atactattac aaatgcatct
    13021 gcactacact tcaaatttta gcactgtata aaaacgtttc aacacactaa ctttaagaaa
    13081 acttccacta ttaattgaaa aagttgatag agataaatta aagatctata ttgaaactca
    13141 tcccgatgct tatttgactg aaatagctgc tgaattcaac tgtcctccaa caactattca
    13201 ttacgctcta aaggctatgg gatatagtct aaaaaagagc cgtacctact gcgaacaaga
    13261 cccagaaaaa gtaaatcggt tccttaaaga attgaatcac ttaagctacc tgactcctat
    13321 ttatatttat gagacagggg ttgagaccta tttttatctc gaatatgatt gatccttgag
    13381 caggcagtta gtctctctgg aagaagatat aattatttga attaagatcg agacaacgca
    13441 caccagagat tgcgatactg ttatagaagt actaataccc ttttttgttt caatatacta
    13501 tggctccgat gacctataaa gatacgatga cgagtgactt tttcgaagct tgcttccaaa
    13561 aattcttact acctacttta gatacaccat cccttatcat tatggaccat gcaaggtttc
    13621 acagaatgaa catgtgtaag gagcagggca tagactgtta ccacttccta cctattcacc
    13681 cgagtataat cccattgaga aaatatgggc ttacatcaaa aacatctcag aataatattg
    13741 tcaaattacg atgcttttct tgaggtactt ttgtcctatt cttgtttcag ccgactatac
    13801 tccgttattg ggcagctacg gaacagtcga tgggacgatg gggggacata aaaaaatcct
    13861 ccagttttgt tttttataac agtatactgg agaattgaca atctcggtag atacctcgtt
    13921 atagcgcggt tacttattag gcagttacaa aacaactgtg aacagaaaac attccagagt
    13981 cagacaagac tttggaatgt tttggctcta taatttctgt agtgggtaat cccaccccag
    14041 gaattatagg gtcgtttctt gtagaaaaaa agccccatat gacctataat gaaaagcgtc
    14101 taaccaactc attagaaagg gttcatatgg aacaacttaa gaataccaca gatttgctcg
    14161 gattggaaga caaaaatatc aaaatcttgt ctgttctgaa ataccaaacc catctagtcg
    14221 ttcaggcaaa gttggattcc cccgctcctc cttgtcctca ttgtcaaggg aagatgatca
    14281 aatacgactt ccagaaagcc tctaaaattc cgcttctcga ctgtcagggt ttacccacgg
    14341 tactgcatct caaaaagcgc cgctttcagt gcaagaattg ccttaaggtg gtcgtttctc
    14401 aaacatccat tgtcaagaaa aattgccaga tttccaacat ggtgagacaa aaaatcgctc
    14461 agctcctcct tgaaaagcag tctatgactg agattgccca cagattggcg gtctcaactt
    14521 ccaccgtcat ccgaaaactg agggaattta agtttgaaac cgattggacc aagttgccaa
    14581 aagttatgag ttgggatgag tatagcttca aaaagagcaa aatgagcttc attgcccaag
    14641 attttgagtc caaatccatc ctcgcaattt tagacgggcg aactcatgcg gtgattcgaa
    14701 accatttcca acgctatcag agagaggttc gggagctggt cgaggtcatc accatggaca
    14761 tgtacagccc ttattatcgg ctcgctaagc aactctttcc aaaggcgaag attgttcttg
    14821 accgcttcca cattgtccaa catctgagcc gagctatgaa ccgagtacga atccaaatca
    14881 tgaaccaatt tgaccgaaaa tccttggagt atcgggcgct caagcgcttt tggaaccctc
    14941 gctttttcgt ttctaggctc gggctaaatc agtccactgg actgatttac tacaccagga
    15001 tagcttcaag ctctgtcaga aacgattcta tcagcccacg tttcgaatgc acttaaccca
    15061 tcgggaagta cgagataagc tgctttctta ctctgaggga ttacaggttc actacgaact
    15121 ctatcaactc ctgctctttc attttcaaga gaagaatgcc gaccatttct ttggattgat
    15181 tgagcaagaa ctgccaacgg ttcatccgct ttttcaaacg gtcttttgga cttttttaag
    15241 ggatagagat aagattatca acgcacttaa gctgccttat tccaacgcta aacttgaagc
    15301 gaccaataat ttgattaagg ttatcaagcg caaagccttt ggtttccgga actttaacaa
    15361 ttttaaaaaa cggattttga tgactttgaa catcaaaaaa gagagtacga atttcgtact
    15421 ctccagattg tagcttttcg cctacccact acacttgaca aagagccact ctttattcca
    15481 tggtatcaaa ggcaagactt ggtttggcat tgaggttcca gcctgcgaag ttttctttgt
    15541 tccactcgct gacactggca taagcaatca tacctgcatt gtctccgcag aggcgcagag
    15601 gtggaatgat gaccttgaca tctgtaacct cggctgctag gcgttctctg agacctttat
    15661 tggctgccac accacctgcc acaaccaggg ttttaacagg atatttctcc aaagccttct
    15721 tggtttttgc catgagaata tccagtacag ctgcttggaa ggaagcacac aaatcctctg
    15781 tagacagact ttctcccttt tgctcggcat tgtgatgaag attgataaag gcagatttca
    15841 aacctgagaa ggagaactcc agattatctt ccttaatcat ggcacggggg aaatcataaa
    15901 tatcctgccc ctgatgagcc agctcgtcaa tctcacgacc tgcaggatag gtcaagccca
    15961 tgacacgacc gaccttatca taggcctcac caaccgcgtc atctcgcgtt tccccaacaa
    16021 tcttgtaatc gccagcctca gaaacataga ccaactctgt gtgcccacca ctgactaaaa
    16081 gggctagcaa gggaaactcc aaaggctcca cactctgagc tgccatgagg tgcccagcca
    16141 tgtgattaac aggaatcagt ggaagtccgt gagcccaagc aaaggccttg gcagctgaca
    16201 aaccaactag caaggctccg accaagcctg gtccgtaggt aaccgcaaca gctgtcacgt
    16261 cctcttcggt aatccctgct tctgccaatg cctcctcgat acaggctgta atgacctcga
    16321 catggtgacg actggctact tcgggcacta cgccaccaaa acgtttgtga ctctcaattt
    16381 gactagcaat gacattggac aagagctcat cgtcgttttt caagacggcg acactggtct
    16441 catcacagga tgtctcaaat gctaaaatat atctatcctt catctatttc tctcttcatg
    16501 ataatggcgt cctcgactgg gtcatggtag taggcctttc gctcagcgat aactgccatc
    16561 ttttctttct tgtaaaatgc ttgcgctcgt tgatttgact gtctgacttc gaggaaaatt
    16621 tccttgtctg tcggcaattg agcaaacaag gctgacgcaa ttccctgacc ctgataagct
    16681 cctttgacag cgatttgcag gacttctgct tcaaaaagat tctcctgcac agctagaaat
    16741 ccaatcactt ctgccccatc ataagccaat gcataccaag tctggtcttg ggacagatct
    16801 gcttggattt gttccagcgt ccaagggttg attgggtaaa cagctatcat aacagcgtag
    16861 atggcttgag ccaagtcagg tcgctgttgg attcgtttga tttctatcat aggcgtttaa
    16921 tgtaagactc gacagactcg gtgtgattct tgagccagtt ttcctcagct tcgacacgct
    16981 tgaggtagtt cggcacaaaa tcatgcaagg agtctgcttc cttgtcccag gcccatagag
    17041 ctagattagc tgcatttggc aatgtttctt tgtaatcagt ccttggcaag tgtttttgaa
    17101 tctgctcaac aaaggggcca acttctccga caaaggttac ctgactagcg cccttgatta
    17161 gctcaatgac tcgctcaaaa ggcagatgtg cttctgccat gacaggtttg gaattttcat
    17221 aaaatcctgc ataaacatta ttgcgacgcg catccatcaa ggggacaaac aaaccttctt
    17281 gttggtgggg caccagagcc aagagactcg acataccaac caactcgatg ttcagggtgt
    17341 gagctaaggt cttagcagtt gctaccgcaa ttcgcaagcc tgtatagcta cccggccctt
    17401 cagctaccac gattcggtcc aaatccttgg gtgtccaatc caaacttgcc atcaaaaaat
    17461 ctatggcagg cataagagta atactgtgat ttttcttaat attaatcgtc gtctcggcaa
    17521 gaacctgctt gtcctctaaa atagcgagag aaagagcctt gctggacgta tcaaaagcta
    17581 atactttcat aacacattcc tatctttttg tctgcttact attatactac aaaagctggc
    17641 acatgggaat tttctttgcc cccagacaag agtgccctca cttaactaaa aataatttaa
    17701 aaaaatgctc acttttcctt ttcttttccg aatataaaag tgaacaagaa aaaaggagga
    17761 aagttcaatg acaaattttg acattcttga caatcaattt ttatccttat ctgaaaatga
    17821 attatcagat attgatggcg gtctcgctcc cttggttatc tttggagtag cagtatcttg
    17881 gaaggctatt gcaggtggaa cagcacttat aggttctggt ttggcagctg gttatttttt
    17941 aggaggagat taatatgatg aaaaatttga acaactatcg tgaaatttct aataaggaat
    18001 tgcaagaaat caagggtggc tttggtgtag gtgttggtat cgctttattt atggcaggtt
    18061 ataccattgg aaaagacctt cgtaaaaagt ttggtaagtc atgctagata agaaacacat
    18121 ttttagaagg ataaatttta ttgtcttcat ctcttacagt ttgctcagca ttctcaatga
    18181 tttgaacatt actactatcc ctttaccatt cgatttatct gtttgtattg ttttattttt
    18241 atgcttcaac tctatttttg agcagaacaa tgactcccat aaaaataata agctttgaaa
    18301 attccattgt catgtcattt tagaaaaatg caaagaccac ctcatcttga tagatggggt
    18361 ggaattttcg tgtcgtaaat ctactatctc tacatcccca aacaaaaaac cccagcataa
    18421 gcagggcatc taagcattta atccaaagta aaatacaaac caaacgacat aggtcacgag
    18481 gaggagaaaa agcgagtaga gagtcacaaa ggtcattttc cacaagaact tggtttgtca
    18541 tcgttccagt ttggcaaata gaagatttcc ttcataaacg caagcaacaa aaacgataaa
    18601 agctagcaaa cgaactccga tagcaaaagc aaataagtta tacatagggc aacctccttg
    18661 acttaaaatc tatatggaat tatgacaagt aataaacttc acttccgtta tcaacataac
    18721 acattttctt tatttttgca aacgctcacc aaagaaatca tcccctaact ttctcgtttc
    18781 cgtcttttac taatttttca ttttgtggta taattgaaat aattgtaacg aatcaaggtc
    18841 aatctagaca caaaatggaa tgaaatcaag caaatatctg ctaaaagttt ggaataagct
    18901 gacctgtaaa tagaaaggaa ctatatgatt tacaaagttt tttatcaaga aacaaaagaa
    18961 cgtagcccac gccgtgaaac aacacgcgcg ctttacctag acatcgatgc cagctcagaa
    19021 cttgagggcc gtatcactgc tcgccaactt gtcgaagaaa atcgcccaga gtacaatatc
    19081 gaatatatcg aactcttgtc tgacaaattg ctcgattacg aaaaagaaac tggcgccttc
    19141 gaaattacgg agttctaata tggcctacac tcttaaacct gaagaagtcg gcgtttttgc
    19201 catcggtggt ctaggagaaa tcgggaaaaa cacttacgga attgaatacc aagacgagat
    19261 tatcatcgtc gatgctggga ttaaattccc agaagatgac ttgcttggta tcgactatgt
    19321 cattcctgac tactcttaca tcgtagacaa tatcgaccgc gtcaaggctg ttttaatcac
    19381 acacggacac gaggaccaca tcggtgggat tccattcctg ctcaagcaag caaatgtccc
    19441 tatttatgct ggaccgcttg ccttggcttt gatccgtggg aaactcgaag aacacggcct
    19501 cttgcgcaac gccaaacttt acgaaatcaa ccacaacacc gagttgacct ttaaaaatct
    19561 caaggcaact ttctttagaa cgactcactc tattccagag cctttgggga ttgtcattca
    19621 tactcctcaa gggaaaatcg tctgtacggg tgactttaag ttcgacttta ctccagttgg
    19681 agaacctgcg gacttgcatc gtatggctgc gcttggtgaa gaaggcgtgc tctgtctcct
    19741 ttctgactcg acaaatgcgg aagtaccaac ctttaccaac tctgaaaaag tcgttggtca
    19801 gtccattatg aagattatcc aaggtattga aggacgtatc atctttgcat cctttgcctc
    19861 aaatatcttc cgtctccagc aggcaacaga agctgctgtt aagactggac gcaagattgc
    19921 ggtctttggt cgttctatgg aaaaggccat tgtcaacgga atcgatcttg gctacatcaa
    19981 agctcctaag ggaaccttta tcgagccaaa tgaaatcaaa gattatcctg caggagaagt
    20041 tcttatcctc tgtacaggta gtcagggtga gcctatggca gccctctctc gtatcgccaa
    20101 cggaacccac cgtcaagtac aattacaacc aggtgatacc gttatcttct cttctagtcc
    20161 catccctgga aacactacta gcgtcaacaa gctgattaac atcatttctg aagctggtgt
    20221 cgaagttatc cacggtaaag tgaacaatat ccatacatct ggacacggtg gtcagcaaga
    20281 gcaaaaactc atgctctgct tgattaagcc aaaatacttc atgcctgtcc acggtgaata
    20341 ccgcatgcaa aaagtccacg ctggactagc agtggatact ggtgttgaga aggacaacat
    20401 ctttatcatg agcaatggcg atgtgcttgc ccttactgct gactcagctc gtatcgcagg
    20461 tcatttcaac gcccaagata tctatgtcga tggaaatcgt atcggtgaaa ttggcgcagc
    20521 tgtcctcaaa gatcgtcgcg atctatctga agacggtgtc gttctggcag tcgcaactgt
    20581 tgacttcaaa tcgcagatga ttctatctgg tccagacatc ctcagccgag gctttgtcta
    20641 catgagagag tctggcgact tgattcgcca aagccagcgt atcctcttca atgccattcg
    20701 tatcgcactg aaaaataagg atgctagcgt gcaatctgtc aatggtgcca ttgtcaacgc
    20761 tattcgcccc ttcctctatg aaaataccga acgtgaaccg atcatcatcc cgatgatcct
    20821 cacaccagat gaagaataaa gcaagaaaac agccccgtcc tcggagctgt ttttctctat
    20881 gctttctttt gagattaaaa ctcatactca atgaaaatca gagagcaaac taggaaacta
    20941 gccgtaggct actcaaagca ctgctttgag gttgtagata gaactgacga agtcagtagc
    21001 catacctacg gcaaggcgac gttgacgcgg tttgaagaga ttttcgaaga gtatcaataa
    21061 aaatcgaaat cagactagaa ggctaagcga aagcataact tgagttagct cccatagttc
    21121 gggaaactat gggaggctgg agatgaatca aagccaagct ttgaactcat tcgtaagaag
    21181 ccgacgacgt atcattttga tttttgaaga gttttagaaa tactacgatt tttaccttcc
    21241 agatacacca tcaaaataga aatatctgct gggtttactc ccgaaatacg gctggcttgg
    21301 ccgatggttt ctggattgat gagtttgaac ttctgacgag cttctgttgc gatagagtca
    21361 atgtcatccc agtcgatatt ggctggaatg cgtttttctt ccatacgtct catcttggca
    21421 acctgatcca tggctttgga aatatagcct tcgtacttga tttctgtttc aatcaattcg
    21481 ataatcttgt catccaagtc ttctgcagct ggtccgatga aggccaccac atcttggtaa
    21541 gaaacttctg gacggcgaag gaattccttg gctgtcaccg catctgtcaa cggcttgaag
    21601 cccatttcct caaccttagc attggtttcc ttgactggct tgagtttgat actgtctagg
    21661 cgtttcatct cattatcaaa ttgatttttc ttgatttcaa aacgagccca gcgttcatca
    21721 tccacaaggc caatctcgcg tcccatctca gtcaagcgca tatcagcatt gtcatggcga
    21781 agaatgagac gatattcagc acgactggtc aagagacggt aaggttcaat ggttcccttg
    21841 gtcaccaagt cgtcgatcat caccccgata taaccgtcac ttcgcttcaa aatcaactca
    21901 ggcttacctt ggattttcag agccgcattg atacccgcga taatcccttg gcctgctgcc
    21961 tcttcgtaac ctgacgttcc atttgtctga ccagcagtga agagacctga gattttcttg
    22021 gtttccaaag tcgcacgcaa ctgatgaggc aagaccatat catactcaat agcataacct
    22081 gtccgcatca tctctgcatt ttccaaacct ttgatggaat gcaccaagtc acgctggaca
    22141 tcctcaggca gactggttga aagtccttgc acatagactt cctcagtatt gcgcccttct
    22201 ggctcaagga agagttggtg acgttccttg tccgcaaagc gcacaatctt gtcttcaatc
    22261 gacggacagt aacgaggccc cactcccttg accacacctg taaacatagg cgcacggtgg
    22321 aggttgtttt ggataatctc atgactggta ccattggtgt aggtcaacca gcatggcact
    22381 tggtccttga cataatcctc atcacgtgaa gtgtatgaga agtgattagg tgcttcatct
    22441 cctggttgga tttctgtcac gtcgtagttg atagaagagg ccttgacacg tggaggggtt
    22501 cctgtcttga aacgaccgat ttcgaggccc agttccttga gattgtcagc taggttaata
    22561 gaagccaagc tgtggttagg acctgatgag tacttgaggt ctccgatgat aatttcccca
    22621 cggagagcag tccctgtcgt cacaataaca gccttagcag catattcttg atgggtggct
    22681 gtacgcacac cgacaacctt gccatcttcc accaaaatct catcaatcat ggtttgacga
    22741 agggtcagat tttcttgatt ttcaactgtc ttgcgcatct ccttagagta aagttccttg
    22801 tcagcctgcg cacgaagagc acggacagct ggccccttcc ctgtgttgag catcttcatc
    22861 tggatgtaag tcttgtcaat ggtcttggcc atctcgccac cgagggcatc gacttcacgc
    22921 acgacaatcc ccttggcaga accaccgata gagggattac aaggcatgaa agccagcatt
    22981 tcaatattga tggtcgcaag caggacctta cagcccatac ggctagcggc caaggaagcc
    23041 tcaaccccag cgtgtcccgc accaattaca ataatatcgt attcttcagt aaaatgataa
    23101 gtcatgtttc tctcctattc ctcaagatga atgtgtctta gttggccttc ccaatctggt
    23161 agggccgttt ttaaaaaggc tggaactagc tggatatcct caagcttatc caagtcaatc
    23221 cactcacagg gctgcctttt ctcatcttcc tgcatgatca atggggcatc ctccagtaag
    23281 tccaccagat aatgaaattc gatattgtga taggaaacgc cgtccacttc aaaacgattt
    23341 tcaaccacaa aagctagctg cccagcttga gctttgacac ccagttcttc cttcacttca
    23401 cggactaccg cgtcttccgt gctttcattg acttgaatcg cacctccaat agtgtaatac
    23461 ttgcccttgt ctttggtaac tagaagcttg tgattttgga caatcaaggc tgtagcccga
    23521 acaccaaaaa ccgtattgtc tacttttgtc cgaaagtctt gttgagtcat tcttgtcctt
    23581 tcccttaaac gacacaaaaa cagtcaaaac tacaaagaag tgcaggacaa aaaagcctgc
    23641 aacatccatg agctttgacc atcatttcta ttgctgttat tattgtagca aattgagaaa
    23701 atttgtcaat ctaaatgtac tgacaaactt gtccatcgcg gtaagcattg tcaatcaaac
    23761 cgccacctag acactcttcg ccatcgtaaa agacaactgc ctgtcctggt gtaatcgcgc
    23821 gttgtggttc cgcaaagatg acctctgcct cgtctccttt gacatggact gtcaccttag
    23881 agtcaggctg acggtaacgg aatttagccg tacattctag cgtaaactct tctggcattt
    23941 cacgagtaaa gtggacttgg ctagcctcta ggctggttga catgagcgaa tcatggtaga
    24001 atccttgtcc tacatagaga atattcttgc ttagatcttt tccgacaacg aaccaagggg
    24061 cattgtcacc accgtgttgc ccaccgatac caagcccgcc acgctgacca atcgtatagt
    24121 acataagacc tgcatgctcg cccatatcgc gaccatccac agtcatcatg cgaccaggct
    24181 gagctggcag gtagttgctg agaaagtttt taaagttctt ttctccgata aagcaaatcc
    24241 ctgtcgagtc tttcttctta gcagtcgaaa gacctgcttc ttctgctagt tttcgaactt
    24301 caggcttttc caaatgtcct agtgggaaca tggttttttg aagttgttct tgcgaaagta
    24361 ggctgaggaa ataggtctga tccttgccat tgtccacgcc acgaagcatg tgaacggtac
    24421 catcctcatc acgcaccact cgagcataat gcccagtcgc tacatagtct gcccccaagg
    24481 tcatagcata gtccaaaaag gccttgaact tgatttcctt gttgcacata acgtccggat
    24541 ttggcgtgcg ccctgcacgg tattccgcta ggaaatactc aaaaacgcgg tcccagtact
    24601 ctttttcaaa attgacagag tagtagggaa tgccaatctg gtctgccacc gcaaccacat
    24661 ccttgtaatc ttcggtcgcc gtacagacgc cgttttcatc tgtgtcatcc cagttcttca
    24721 tgaagatacc gatcacatcg tagccctgct ccttgagcaa aagagccgtc accgacgaat
    24781 caacaccacc actcatcccc acgacaacac gtgttttaga gttatcactc atggtaagtc
    24841 tcccatctat tcgtttattc acgattgaag gtcgtgtgtg cttcacgatt gaaggtcgct
    24901 tgagcagtat tcattataac acgcttggtt ggagaagaca aggaagagtt taaaaattat
    24961 tttttaaaac ttatagtcaa tatacagatt atgtgaatga tgtgagtata ccttcttctt
    25021 atcttcattc aaataactat aataaataaa taaaacaacc cattttctct aatctatttt
    25081 tcaagttaga gaaaaggagt cgttttttta atgacatttc ctgaaatcat aagataggta
    25141 cctaaagaat acgaacataa atctattcaa tcgaacctta tctttgtttc aaaattaaaa
    25201 tgtcaaatgt tcttaacatg atttaattta atcggcttaa acccattcac cattggcatt
    25261 gacttcatag ccatctacag ttgtgttgac tgcaagggca cctaagccat tgacatagta
    25321 ccatttatct gatactttga accattggct tgctttcata gcacctgatg cttcaagata
    25381 gtaccaggta tctccatctt tcacccaacc tgttgccatt gaaccgttag cgttgaggta
    25441 gtaccatgaa ccgttgactt tagcccaacc tgttgccata gcaccgttag cgtttaggta
    25501 gtaccatgaa ccgttgtatt ggagccatcc tgttgccatt gaaccgttag cgttgaggta
    25561 gtaccatgaa ccgttgactt tagcccaacc tgtagccata gcgccgctag cgtttaggta
    25621 ataccatgaa ccgttgtatt ggagccatcc tgtcgccata gctccattag cgtttaggta
    25681 gtaccatgaa ccgttgactt tagcccaacc tgtagccata gcgccgttgc tgttgaggta
    25741 ataccataag ccgttgactt tagcccaacc tgttgccata gcaccattag cgttgaggta
    25801 gtaccatgag ccattatttt gtagccagcc tgttgccatt gaaccatccg tattgtagaa
    25861 gtaccacata ccattttctt gtttccagcc tgtttttgga gtttctggtt taggagctgg
    25921 agctggtttt tctgctggct tttctggttt aggagccgga gctggtttag gagccggagc
    25981 tggagctggg gcttctggag ttggagctgg agctggggct ggagccggag ctggggctgg
    26041 agccggagct ggagtttctg gctcatcaac tgctttctta aggtcagctt cagctttttc
    26101 taattcagct tttttctcag cagtagtttt ctctaaacct tctttaaagt aggcttctac
    26161 attattgttt ccttcagcat ctttaagttg aacttcaagt tctgcaattt cagcgtctaa
    26221 ctcttcaatc ttaccactca actcttcaag tttcaatagt ttagcttttt tggtatccaa
    26281 ttcagattga agaggagcac ggagaccttc tttaacataa tcttctgagt cagactcatt
    26341 aatatctttg agatcttgtt ctagcctatg aacttgattt tccaattcag cgattttagc
    26401 ttgaggagca acttctttag catgttctgc atccactttt tgtttggctt cagtagcttt
    26461 tttctcagct tcttctgatt ttgctttagc ttcttctagt tttttagtaa gctctggttc
    26521 tttttcttta gctttctctg ctttttgtct agtattttct aattcttccg cgctaggaat
    26581 tacctttgcg agaactttag caagttctgt ttgttttttc tcatgctctt tcttagctgc
    26641 agtcattact ttctcagctt cagttctttt tgttgaatta ttttcacgtg tatatttaat
    26701 atatttaacc aactcttgtt gatatttcag atttgcagct tgttcttctt ccgaagcttt
    26761 ttttacttct ttcgctttct cctcagtttt cttttgatcc tcgtcatatt ttttctgagc
    26821 agcttttgca tcatctaaag ccttttgagc atcttctact gcttttttcg cattcttagc
    26881 atttttcact gctgcatcat agtctttctc agctttagac tgactagcta cgggagattc
    26941 ttctgctctt acaaaagtag gctgagacgc aacaaaacca gcccctaaga tagcgacgct
    27001 ggctagactt gttaaaatca tttttttctt attcatctaa atttacctct tttctgatag
    27061 tcatttttag actatactta tattaagtat actccccccg taaatatttg tcaaatgttt
    27121 tatattacat ttttattaca aatttctata tcataagctt ctactccaaa aagataaaga
    27181 cactactttt gcccttttcg attctctttt taaacatagc atcatcttcc ttcattccta
    27241 taaaaacatt tccgatgaga gagcttgttt tttaatttcg ttaaacaaca aaaaacgcaa
    27301 gcttaagtct gcggacaatc tttatagcca tttcatttct ttcacatctg ttttacgaac
    27361 tttagcatat ttcttagcgc ttgtaaaatg tagagtaact ggtttaaata cttcgctttt
    27421 gtctcttcgt aaacctaaaa ctgcggatct tttattttta tcctcaaaaa atatgacgtc
    27481 caatttcata gtatttttag ataaatcctt agctacgatg caacaacttg ttattttaga
    27541 atagaaaata tcgccgataa actcacataa agatatcctt tcgattacat cattgtacat
    27601 aggatatttc taaaatcttc taaaataaaa acaccagctt gaatagcagg ttttgtttga
    27661 ctagcataat ctcgtgtgat tttgtgtaag ccaaataaat gatgtaaatc agtcaagcaa
    27721 aaattcactt tgaaaatctc taaatactta taattcgctg atacttgaca tgtttttcca
    27781 ttgaatcttt cttgataatc caaaatacaa tcaagtaatt tcaacgacaa gaaagaggct
    27841 gataatcgac caacctctgt ttttagatac agttcaagtc caaactattc tttatagaaa
    27901 agtccgataa attcgagcaa tagttaacat acttacaaat ataactccca aaatagataa
    27961 cactattttc acaaaactca gttccgaacc tatgacatat atatgaaaaa gaggagctag
    28021 tcctacacat atatacaata agtagccaac aagttttatc tcaccaattc ctgcaaaaaa
    28081 atgtttcatg tgacgattct ccatttactc tattaaatca attttatttt agactatcat
    28141 aaaacaatca cctcttcaat aaaaaccatt ggcgaatact attctgaagc attgatagct
    28201 cagatttctc agaatagagc tatcctaact atcgagcagc tcaaatacat atatatgagc
    28261 aattctaagc ctagaattgc tataaaataa atgttttcgg gctattctaa gtctttgact
    28321 gcttaaaatt ttacattctg aaggattcta aacctagaat agctcaaaat cacgagaact
    28381 aaggtattcg aaacttcaga gtaatacaat ccccatagga attctccatt cttattaagc
    28441 atgattaaaa tgtaatccta acaagtgatc ctcgattgtg tttgtagcac ttagttacct
    28501 agataagact atttcccttt atcatatctg attttaagcc gttctaagat ttaacctatg
    28561 tttctattac ttgctatttt taaataattc gaattccttt tctttgataa atggaactga
    28621 aaaattagaa aaaagaagta aaaccgaaaa caaatagcct gctttttgaa tcactaaaag
    28681 atatcctaaa aataagtaag ctataacatc caatgcgaaa agaaaaaata ttctcctctt
    28741 cattaaagta cttgtgtcaa ataatctgat gaataaaaat tttatcgtgg tatctgcaca
    28801 aatttttatc aaaaagataa gagtcagtac atgattatca actgtaccat aaagaataga
    28861 tggaaatata gttaatataa aactagaaat ctctaaatat tttatccaag gagattgaga
    28921 caccttgctt ctaaactgac taattttctt atattcgtta gtcaatttaa tatcaaaatc
    28981 tttcccaatt aaatgaaaaa ttatcaactc tgtaataaaa acacttatta atacggtata
    29041 agtcaaaaaa ctttctggga aaaacttatt gattaaaatg gggaaactca ttaacagaat
    29101 cgaatttatg gctagacaga tagatactat tttatttttc acagaatata gaggtagtga
    29161 tactattgag tagataaaag ctaaaaaaat aagcaaaaaa tactccgtgt catttataat
    29221 cgccctgaat gataaaaata tatacatcca acatacgata atgtgtattt ttcgaatctt
    29281 atctacatta ctcatcttac tgtcgcagat atgaatccat cccaaggata agggttcccg
    29341 ctaatatcac aacctctatt aagagcacca tatccaatac agtaagttat tcttcctgcc
    29401 gccccagcca atacacctgc tgctgcacca ataagccagc ctccaagacc tccaacctta
    29461 atatagttta ttagtttttt ggttaaaact gcagctccag tcaatgctat aaaagttcct
    29521 gaactcatag ctaaagctgc gcaaattcct tgacaagcac gcttgcttaa ataagctccc
    29581 ccatcaagat acatcatttc ttcttcatca atcacaacat aattatttgg taatacaagt
    29641 tccatttgtt ttctcctcct tagttgaaat tgtttcattt gttttacaaa taggacaaac
    29701 ttaaactatc tttttattac tcagtaataa tttccgagat ttcattttat gatactctct
    29761 attcatacag aaatcaaaat tttgccttaa ccaacttgta taatagaaaa aatctaattg
    29821 atttattctg atgagctgta ttctaatttt atcaaccttt tcttgccagt tgttattgtt
    29881 actaatagaa atctcataca gcagtaactc gacaagacct gtacacagaa gggtgttatg
    29941 agaatcttca attttactca gaatatcctc aaagagttca ctatccgtta aaaaggtgga
    30001 ttggttcatc gcatcataca gctgaagaga cattaagtca gaatagctta attctgattt
    30061 ttgtatctta tcctttaacg tatttgtcaa atcactttca aacgaatctt ctttttccca
    30121 tttattttga ttgaaaagaa attccgtctt attaaaaacg agatgattga tatccattat
    30181 agtccagaaa aatattgtag taagcatgat gattgcaaaa ggaattttta aaataaatac
    30241 tagaataata gcaatttcaa gaataaaact ccatataatc ctagatctta aatcatcagg
    30301 cgacaaactt ttacgatgga atgaaaaata gggcgagaac ctcacattta tttttttcct
    30361 tcttataaaa ataaagggaa aaatcttaat aagaccttct ttcttgtata aatctttcaa
    30421 tgcgtatagt atgtctaaaa ctatttttga taatatcaaa acaaaaaaag taagactcgt
    30481 actaaccaca aaatcaaagg gaatttctag attcaattgc aagttattca ctaggacatg
    30541 caactctagc cacaagacaa aaagagggag cattaataaa aaaatgatta gtttacgtat
    30601 cataatttta cagtgtcctt atcattttct tgattttgga taaattatca ttgctacgat
    30661 taaaatcaaa aaaacgacat taatccaaat aatcaacttt tttatttctt cgctaacaaa
    30721 atcataggct aaaaaagtta tggatgatat aaatagacat acaaaaaaaa taataacaaa
    30781 aattttttcc attttaatac ccatatctag ttaccacaag gcgtttaaat ttgggtctct
    30841 cctatttaca tcattgttgg cccagattgt tgtaatagca tcgccaattg acatccaagc
    30901 tgcaaatcca ttaatagcag acagtgcaaa ttctgccact ctatttgcaa ctcgtacccc
    30961 aacatatctt gcagctgctc cagcaattgc gcttgtaact cgccgcaaac cataattacg
    31021 aatataattt ctaactagac tgattgctcc tccacctaaa acaccattaa aagctatatt
    31081 aatggctgtt gcaacaggcc atctcagaat agaaaatccc ccatcaagat acatcatctc
    31141 ttcttgctca agagcaacat aattatttgg taatacgagt tccatttatt ttctcctttt
    31201 ttattaagca tagttaggat agtttcctaa caagtgatag acgactgtgt ttttatcact
    31261 tagctaccta tataagatat cctttctcta ccttatttgt ttttataggt tacctaaggt
    31321 ttaaaatcaa ttattgtttg aaacttaaca gttctaaacc actagcaata aatgattgcg
    31381 aactcactaa tactatttca aaatttattt tttttgactt agtaacgcaa ttccaattag
    31441 caatacacct aatataaata aaagtatttc ccaaaattta ttctcagttt taataagtgg
    31501 aataagatac atactgacta atatgcaact tgcccctata atggcaaata ttattctggt
    31561 tttatctcct aattgaaaca tgtttgatcc ccatatacac ttcaagcaaa agttggattt
    31621 ctgaaatggc taaagataaa gataagggtt gcgagctatt taaactatca tcaatattct
    31681 gctcgattaa aacaaagtct ggtcttacct ctaaaatttt ctttaacatt gattcatatt
    31741 tatttttttc attataatgc cgtaaatata gatttaattt tataacatcc aacataccat
    31801 aaagtgatat tggatgattt atttttttaa atcgcttaac ttctaataaa tcaatttgtt
    31861 cacgcacact ctctgaaaga tatggcttga tcaaactgat ataagataaa gccacgcatg
    31921 gcaactcaga ttttgattgc aatttccaaa tttcatgata atcctgaaga ttaaactcac
    31981 aatccctctt agattccagt attgttagta cttttgattt taacagaaat aattgttgat
    32041 tctcaattct ataaagtttt tgtactaatg ctatgataat agaaaatgga ataagaggca
    32101 aaagcaacga tttgtcatac acaaaagtaa agaaaaaata gtatgaaatt agtgttgtaa
    32161 agtacaagaa gtagtaaaat ttaaacagat tcttagttgt ttgactctcc ttataaaaca
    32221 ctgctattcc tggactaaat cccattagtt ggtgaaagag aattcgatag tatttcctag
    32281 ctcctataat gatcacaaat ataaaataaa aataaattgg tcttaattta caaaagattg
    32341 aggaaactag taatagcaaa gtatgtaagc attgagacaa aatatagaat aacggtatcg
    32401 ccaatacaaa ggttaagatg gcatgagagg gagttcctaa gatgtccaat tttataaata
    32461 ctgggctgac acaaaatatc gtgcttataa gcagtaaaat tattaaaatt gtgtcaaaaa
    32521 aataacgctt atttttcatt agtctacttt ccattgttaa ataatactac tgctaacacc
    32581 aagccaactt agcacattgc atcacctaat cctgcgctac ttgtccataa tcctttaatg
    32641 tttctactaa aattattcca atctccccca tcaagatagc ttatttatcc tagacaacgc
    32701 ctactgcaac agtataaata agattcatca gccatctttt ctggcaatca tatgggtaga
    32761 ctaatgatat ttctagttac tcaaaaatat ctagctatac tagagttatt tctaatccct
    32821 aggacacttg ttaatccaaa tgtaacaaat tttcacccct taataggact ctttctggaa
    32881 aaaatataag gtctatcttt ataaaaaaat ctatcatatt gggatggcac gcatctggaa
    32941 tttaaacaag ctataaattc atttataact actatttgtt tagaggcaac agcatcttgt
    33001 ataccgtcct cgaaagaacc atcttgtaat tccgaaatat ttttgtttaa atattgtttt
    33061 gacaaatctc ttaatgcttc attatcgtaa atgattccca aaaatccaac cttatatagt
    33121 aaataattta aacttacaaa gtaattgaat cccatagtat atttttcttt ataaagcaaa
    33181 ggtaaaactt tataaaaaat atctaagtca acctcactct gattctgaag caagtaggag
    33241 tcaagcaaat tttcaaaaat agctaacaat atgattggtg taaagttttt gtattcacat
    33301 gtcaagtatt ctgagtatcg tgcagatgat atttctttta tataactttt tgaaagcaag
    33361 attttttcaa attcatcatc tattattaat cttctatttc caatccaagc ggtattacca
    33421 cccaaataag attgtgcaaa tagcaatatg taagaaaata tgaacgtaaa tactgaaaga
    33481 ggtagaattc tatgcgtaaa aaaatagacg ataatggtag ccaggagtaa agatatctct
    33541 cgtgacaatc gaattctttt cagcatcttt tttaacagtc cgtaaggttg tccttggcaa
    33601 tattcttgaa ctaaattaat cggaatgaca tctctcacca tttctggaaa gtagagtaag
    33661 tttataggtt gaaatctcca gctcccatca taagtaaatg gatatagaac caaatactta
    33721 aaagattttt ttcttataaa cttaattatc acaatatgaa tgactgttgc aatgaagtat
    33781 attaaatata aaagtaaaac cgccatcaat atacttacaa aaatcccctt ggactcaatc
    33841 aatggaaaat aaaatattgc aactagaagc gaataaagtc ccgctaataa atatttctga
    33901 tcatctttca ttcaaaacac catattattt actaagaata catcaataca atagagcaac
    33961 tctgtaagtc aatatttgat aaagcaaagc tttaacccct tccccagacg ttagcttttc
    34021 ttcaacccac tacagttgac aaggagccca aattattgat aaaaacttta gtcatcatcg
    34081 tctctataaa aatattttct atacactctt gataatacca aaattaatgc caatatcata
    34141 ccaagagcta taataataga atttattaga tttattttag tatatccaat cactagtcca
    34201 ataattggac tagcagacat gcttagatat aataaaaata acaaaaaatg aatttcacca
    34261 attcctgcaa aaaaatgttt catagctata gttttacgcc cataaatacc catcaaattt
    34321 accgtctacg atatctaaac catatgcaat ggctcctcct aatgagaaga cttcagcaac
    34381 agtagccgca atattaagag cattagtaat agttgccata ctaactccac caatatatct
    34441 tgttatagca cttagttacc tagataagat atcctttagc ttgcttccaa aatttaagtc
    34501 tacacctata atatgagttc atattagtac tgctaaatcc tatctatagt aatgtcaaac
    34561 acctaaataa agtcatctct ccaattcatt caagaaatga agaaaggcaa aaaatcttta
    34621 aaataagaaa aatgcatatt atcaggtgtt caaaaatatt gatgatatac gttatataga
    34681 tagaaagatt tactcaattt cactttcaaa ttgagttttt tcccaacctc gtttttaatt
    34741 tatatcttca ataaaatcta atgacctagt tgatatgtca tatggaataa tattatttaa
    34801 tctgtaattt ttttaaaaaa cttaataata aatttgctcc actgattgct atcaatattt
    34861 caattggtaa aaaatagtaa ttccaaataa aatgagaaat cagcaatgat agaaaaataa
    34921 caatatcaat tttcctgttg ttgacatact ctgtaatttt atggtacagg aatgcaacaa
    34981 taactgaaat taaaacaacc atcataatac tattatccta ttctcaattg attatcacgt
    35041 cgcccatccc agccatcaat aatattggta aaaatccaat cagctccagc accaattcca
    35101 gcagatgcaa tacttctaat aacagtattt gcaaaagcat ttccaatatg aattcctaat
    35161 actcctaaac ctttaacaat cccagctacc agtgcggagc gtaatccata agatgcaaga
    35221 actagttgaa ggcctccacc tcctgctgct gctaatgctg catatgctgc accagtaatg
    35281 gctcctgtaa ttgcccacct ttgacctaaa tcattcttaa cttgaagaat cgcaggaaat
    35341 gttaattttg gagtcaaatc ttccagtgct actcgaacag cttttactgt aaaattcaac
    35401 ttattcagac ctaaaacaat accactgaca gtcgttccat acatgtctgt accaataatt
    35461 tcccgaatct tcatgattga tagttccttt ttgtaagata aaagaactgt tgaaacaact
    35521 gccgcagcac aatctgactg atcatgttgc atcgtacaag gatatttttt taacatagaa
    35581 atactcaatt ctttagaatt aatctaactt ttctttgatg tcacccaaac ctcaatcact
    35641 gcccagtagt tcttgaatca gtttattttc aatcgtatca ttctttgttc ttgatatctt
    35701 tccaagcatt gtagtacagc agatttttgt ccaaggacta agcctccttt aacaactcaa
    35761 gctcccttac attatatcga ccagccccat ggaaagatta tggccagact aatcaatgat
    35821 ataatacata ctagaataca aaatattttt ttattcatac tttttctcct atctttattt
    35881 tctacctaca tcatacctct tattaagctc attttaaaat tacgttaact tttttcacaa
    35941 atttatttcg actttctttt ttacttttta cattgctatg atacaatatt tttaacaaga
    36001 ttttattatt tgttaacttt tttcacagaa aggagaaaat catgcgttat gatttcggaa
    36061 aggtctataa agaaatacgt gagtcaaagg ggctgaccca agaagaggtc tgtgggggtg
    36121 ttctctcaag aaccagctta tcaaaaatcg aaagtggcaa gacaacccca aaatatgaaa
    36181 atatggaatt tcttctccgt caaatcaata tgagttttga agagtttgaa tatatctgtc
    36241 aactttatca accaagtcaa cgcacagaga ttatgcaaac ctatctcaat atgcgttcca
    36301 ttatcgggac cagcgatctt gtcaatttat ttcaaaaatg ccaagactac ctcaagaccc
    36361 accacgatct ccctatagaa gaaatcagag atatgcttga agttgtcatt tatatccgtc
    36421 aacacggggc aggggaacta tcagatcacg cagaacaggt tgtcaaaaaa ctttggagaa
    36481 aaattgaaaa acaagataca tggtatgaga gtgatctaaa aatcctcaat accattcttt
    36541 tcagttttcc cattgaatac ctccatctca tcactggaaa aatattgcaa cgcttagaag
    36601 tctataaaaa ctatcaacat ttatatgact tgcgaatagc aatcctgctc aacctttcca
    36661 cactctatct atacaatcaa gataaaaaca tgtgtaagca aatctgctac actttactgg
    36721 aggacgccaa gaataagaaa agctacgata ggctggctat ctgctatgtc cgcattggga
    36781 tttgtacaga cgattctaaa cttatccaaa aagggttctc ccttctggag ctgaccgagg
    36841 aaacttctat gctgtctcat ctcaaaaaag aagtagagac ccattatcaa ccaaagaaat
    36901 tataaaaaaa gtcgagggag ctcctcgacc ttttcataga atcgccgaac gatttaacga
    36961 gaaagtatga cttttacgtt tatcccaact caattatgac atttttttca aaagtcaata
    37021 tatctcactt tttcaacgac aagaaagagg ctgataatct accaacctct tattctgaac
    37081 ccatcactcc atcacttttt agcttcattc gctttcttag cgactgcaat ctggtattcg
    37141 acttggtcat tccccttacc ggtacaacca tgagcaattg tagtcgctcc tatctgatgc
    37201 gctatttcaa ccaatttttt agaaatcaga gggcggctca aggcagatac caagggatac
    37261 ttttgttcat aataggcatg tgactgatga gccactagca cataatctgt agcaaattcg
    37321 tccttgacat caatgacata agattcgact gccccaacct tgagagcctt atcatggatg
    37381 aagtctaagt ctttcccttc acccacatcc atacaaactg aaacaacatc atagtctttc
    37441 tttaaccagg taatagcaac tgatgtgtcc aaaccgccag aataggccaa aattactttt
    37501 tctttactca tgttcttttc cttctttcta tttttcaatg gatgctttaa aggcatcctc
    37561 aatgagtttg tctaattccc cagactcctt caacttttga atggttttat cgactgcctc
    37621 tttcaattcc ttgctatctt ttttcatggc taccgcgtag gaatcatctt gctctttttc
    37681 aaaattgagg tctgcgattg ctaaatcagg attattttcc acaaatccct tggaaacagg
    37741 ttcttcaaag ataacggcat ccacttgtcc tgattttaaa tctgtgatta aattcccatt
    37801 tttaggcaga gatacgaggg aagaattttg tagcaagtct ttcgccatcg tctcttgaat
    37861 cgaaccattc tgtgctccga cctttttctg cgctaagtcg ttgacagact gataagtggc
    37921 caagtcagat tttttgacaa tgagtttatt ttttgcagta tagtagggag ttgaaaaatc
    37981 gaacaccttg ctccgttcat ctgtcttaga aacaccagat atggcaagat cggcttttcc
    38041 tgattgaaca ctagccagta cattgtcaaa actcatggga gatagttcca attcgacacc
    38101 tagttctgtt gcgatagctt tggctaattc gatatctgaa cccacaatct gatttttccc
    38161 atctaccact ttttgatatt caaatggagc aaaatctgga ttgagggcta caaccaattt
    38221 tcctttggac ttgatggctt caattccagc cgattgattg ttactacaag caaatagtag
    38281 ggggagcatc actaaaccaa acatcgtcat caacaccttc ttcatcttat tcataacaaa
    38341 gcctccttta tgtttattct tttttattgt ataaataata ctcctatact catcctttgt
    38401 caagcctaaa ttgaaaaaat tttcaatttg aaacaaaaaa aacctagaaa tactacataa
    38461 aatgtcattc ctaggcgtat ttatgctatt tttctctgga aaacatgagt attcagccag
    38521 tcaaaaggag ctgaatgaac tcattttccc tcgcccaatt caatgacacg atgacattgt
    38581 tgggctacat aagcatcgtg ggtcacaata atgactgttt tcccttctcg attcatctct
    38641 aagagaaact tcaagaccaa atctctattt tcaggatcca gcgaacctgt aggttcatcg
    38701 gctaaaatca gctggctggg ttttaagatg gctctagcaa ctgcaattcg ttgttgttcg
    38761 cccccagaca actcggagac cctttgatgc aaagtagctg acaaacctac tctctctaaa
    38821 atctcttcca cctttttgag cttgtctttc ttaggcaatt tcacatattt cagcgccagc
    38881 atgagattgt actcgaccgt ttcatcatca atcagggcaa aattttgaaa cagataagag
    38941 atatgttcac ggattattgt ttgcgactta gcagaattaa ccgctagatt tgtctgacca
    39001 aaaatctcat accgtccgct ataatcacca tctatcaaac ccaataaatt taacaaggtc
    39061 gacttcccac taccactctt accaacaata gctaccaaat ccccctgatc aatcctgaga
    39121 gataagttat ccaaaatcac ttttccccca atggttttgg taatattttt caactcaatc
    39181 ataagatgcc ccctttcaat aactctacta gacttctttt ctccatccta gaagctaagc
    39241 ctagcacaaa tagtatatcc agacatgtaa aacctgcaaa cagtagaagt ggtaagaacg
    39301 catgggcaaa gaaaatcaag actagaagag ggaaactata gcccagcaag agcagaacga
    39361 ggagaggacg gtagcgatcg accagtttcc accccataaa cttcttggta atgatatccc
    39421 tgcgcttcaa taagaaagtt gttactagta agaagtagga aatcatcatg ctaaggagac
    39481 caaacaaagc aaagagtagg ttaaaattcc gaacagcatc tcgataagaa tccactttct
    39541 cttgttgaat ggcttgaata gatgaaaatt ttaaataatt tccatctgac aatttctcaa
    39601 ctaactctgt aatctctttt tgatgttgaa ccgtattttc aattttaatc ggattattta
    39661 agccagttgt tgacagggag gctttctcat cccacatcat atcagaatca ttgaccaagc
    39721 taataattgg attggagaga ttttcctttc gcttatcact atatgggaaa aatgaccaat
    39781 ctccttcata ataggcaatc tcgacatcca tctcctctat cgttcgtttt tgctgctctt
    39841 catacttcat cgaatgaaag gcaattaact tccccaagag ctgattttta tcttcttcac
    39901 ctttcgtact tgctggcatc aaaataactt ttttaatacc ggtatctggt agcttgaatc
    39961 ccttgctctt tagaaaattg cgattggcat agtaaacatc caccgtatct gttaactgat
    40021 attgctgaat ctgttctgat tggacaaaat tttttacagg aagactgcta ctctgcacat
    40081 agcccgcctg cgttttttct accaaatcct gataaaatcg atagaaataa tctgtagatt
    40141 tccctgaccc tgctagctct tcttgccaca gattatcatt gagtttgaag gtttctaagg
    40201 tcaggtaatt accttgactt acccactgtt gctgataagc aagttctttg ttttcttgtt
    40261 ctaaacttct gcccacccca atcagtaagg ccgtcagtaa aatagttgtc cctattttca
    40321 tcacataatt gaagataaga ccaaatttga aagatgaaaa acctttcagc agagagctga
    40381 ttgtcatttt ttggattaag aggtaagtca accaactgat aaagagataa agctgcaaca
    40441 gcaaaaaatg agacaaccac agcataggaa acaaatcttt tggcttataa tcaagcaaga
    40501 aaaacacgcc tagattgatc acaagagccc cacctaggag gaggtaaagg ttgcctttta
    40561 caacatcagc taaaacagcc ctatcttgaa aaccaagtaa tttttgtacc ccaactcttt
    40621 tcatctccat catcggttga tacactgtca ctaacacaag aagcaaaata gccaagacaa
    40681 aaacaatggc agataaaagc aaatctcgat ttatgacttc cactgcactt ttgtaggtcg
    40741 gctctagcaa ggtagcctgg tctatcttga aaaaatcgct ccatttctgt acaatcctat
    40801 ccttgtccat ctcttgtgta gaagttatcg tatagcgacc atttaaacta cgagatgtat
    40861 ccttgatata ggtttgaaaa gtcataagct gaataggttt ggcttttaga aaggtcggaa
    40921 tcgtaccaag tttattggaa atttctttat tactatagac tccttcacca tctgtggtaa
    40981 aatcaagaga agaaatccca aactcttggt aggggaaggt atctttatca aaaacaccag
    41041 acttgaccac ctcatcacca ctgtctgttt tgatgatgga gactttatac tcctttgata
    41101 catcctcaaa aaatcgaaga acagacgctg caggttcgtt aatatctttc aaatacaaat
    41161 ccaaagaatc tacagtcttt cccatttctt gaatccgaac cacttctcgt gtatagttta
    41221 cattaaaaac aaaaaaagtg gtacacagaa gcaggagtaa catacaaaga tgactgattt
    41281 ttttcataga gatacctccc gtgaagaaac tccctctcca aaaggggagg gagaatttta
    41341 attaaaatcc atagaaatat tccattcccg ttggtgggaa tttgaagatt gaagcccgag
    41401 cccatgcctc agcttctgca cgatccttag agaatttatt tccatcttta acagttgctg
    41461 tatgagagcg agtagaatgt aaataatcag aataaccaaa atttcctgac catcctactc
    41521 catagttcca ttgaccacca tcaacccata ctgccaaaac acttgtagaa gcaagtatac
    41581 tacataccat taaagatgca acaccaattt tctcatgatt tatttctcct attatcgaga
    41641 gctattccgt agaaacagct atagtaattt gtcaacaagt atcgtagtcc attggactca
    41701 ccttccttct atctcatttc atttttaaac aacgaactta ctcttaacta gaagaatagt
    41761 tctcttctgt atcaggtctt tgaacaacca gagtagtatt aatcacactc taactattac
    41821 tcaagaatca gcccaataaa caatatggat agcgctttca aatttttaaa ctcttatccc
    41881 atccttttat ctatataata agtgaaaata taataactgt caagtaatcg aagtgaattt
    41941 tataaaaaaa aattacaagc caaatttgca aagtttacaa taagccgcta gggcaatcgt
    42001 ctatcagaat gtccgtttat ttgtcaataa tccgagaaaa tcttgcaacg cttagaagtc
    42061 tataaaaact atcaacattt atatgacttg cgaatagcaa tcctgctcaa cctttccaca
    42121 ctctatctat acaatcaaga taaaaacatg tgtaagcaaa tctgctacac tttactagag
    42181 gacgccaaga ataagaaaag ctacgatagg ctggttatct gctatgtccg tattgggatt
    42241 tgtacagacg attctaaact tatccaaaaa gggttctccc ttctggagct aaccgaggaa
    42301 acttctatgc tgtctcatct caaaaaagaa gtagagatct attaccaagc gaaggaaaga
    42361 taaaaaagcc gagggatttc ctcgactctt tacatattat ttgttcgtta gttcttaata
    42421 ccagccattg ttaagccaga agtttttagc agcagtccat gaaccgtaac gtcctgcaac
    42481 gtaggcatct gctacacgtt cttggttttc agctgagtag tcaccgttca ggtatgaatc
    42541 tgttaattgg taacgtccga tataacgtcc atttgtagct gtatagctac cacctgattc
    42601 tttttgagcg atccattctt tggcttctgc ttcagatccg cttacagttg aaacaactgt
    42661 ttcacttact actggagctg aaacagtttc atcttgagcg gctggtgccg cataagtagc
    42721 tggcgctggt gttgcaacag gcgctacagg gccatcgata accaactctt gaccaacata
    42781 aatcaaatga atgttatcaa tgtggttgtt ttctgccaat ttttcaactg ttgtgttgtg
    42841 agtttcagcg atttctgaaa gtgtatcacc ttctttaaca gtgtaagttg atgattcttg
    42901 agcagataca aatgatggag caaatactgc aaacaaggca gctactcctg caagagttgc
    42961 tttaatcttt ttagttattg atttcatatt cgaaaattct ccttctttct atagttctat
    43021 catacccttt aaatattacc gtttcttgac acttttatgt agaaatatta caaaattatt
    43081 ttttatttcc ctaaataagg tgttttttgt cataaaagat actattttta tgctatttga
    43141 ggtattagaa aggttttcat ccacaattaa agccaagccc ctcattcttt gatataatag
    43201 agataagaat ttttataagg ggaaactgat gaaatcactt cgttttcaat ctgtctttga
    43261 tatcatcgga ccagttatga ttggcccatc tagtagccat accgctggtg ctgttcgtat
    43321 tgggaagatt gtctcttcca tttttgatga tactccgaca gaagttgaat tccaactttt
    43381 taactcattt gccaagacct atcgtggtca cggaacagac ctagcccttg ttgcaggtat
    43441 tttaggcatg gatacagatg atcctgaaat tccaaacagt ctggagattg cccacaagcg
    43501 tggtatcaag attgtctgga ccattcagaa agacagcaat gcccctcacc ccaacaccac
    43561 taaaattacc gtcaaaaatg cccacaagac catcagcgtg actggtattt ctatcggtgg
    43621 aggaaatatt caggtaaccg aactcaatgg ttttgccgtc tctctcaata tgaatacacc
    43681 gactatcatc atcgttcatc aagatattcc aggtatgatt gcccttgtta cagaggcgct
    43741 ttcccgctat ggtatcaata tcgcccagat gaatgtcact cgtgaaaaag ctggtgaaaa
    43801 agccattatg attatcgaag ttgacagtcg caactgtgat gaggctatcg aagaaattcg
    43861 aaaaatccct catctccaca atgtcaattt ctttaaatag gaggaagcat gttttattct
    43921 atcaaagaat tggtcgagca agcagatctg gactttcaag gaaatgtcgc agaactcatg
    43981 attacaacag agtttgaatt gaccggtcgc gaacgtgaag aagtctttct tctcatggaa
    44041 cgcaatctgg aagttatgaa agcctctgtc caacttggcc tcaatgaaaa taaatctcgt
    44101 agtggcctga caggtggaga tgctgccaaa ttggatcact acatcaaaaa cgaaaaaact
    44161 ttatcagatt acacgattct ctctgctgcc cgaaatgcta tcgcagtcaa tgaacacaat
    44221 gctaaaatgg gcttggtctg cgctactcct accgcaggaa gtgccggttg tctcccttcc
    44281 gttctcactg ctgctattga aaaattagac ctcagccacg agcaacaatt ggatttcctc
    44341 tttgctgctg gtgcctttgg actagtcatc gcaaacaatg cctccatctc aggtgctgag
    44401 ggtgggtgtc aagctgaagt tggttcagcc tctgctatga gtgctgccgc cttgactctg
    44461 gctgcaggtg gaacacctta tcaggccagt caagctattg cctttgtcat taaaaatatg
    44521 ctaggcctca tctgtgaccc tgttgcaggt ttggtcgaag ttccctgtgt caaacgtaat
    44581 gccatgggag ctagctttgc tttcatcgca gcagacatgg ccttggcagg tatcgaatct
    44641 aaaatccctg tggatgaagt gatcgatgcc atgtaccaag taggagcaag catgccaact
    44701 gcctttcgtg aaacagctga aggtggactc gctaccaccc ctactggtcg tcgcctccaa
    44761 aaagaaattt tcggagaata agcttatcaa ataggagaaa ccatgacctc tatcacagcg
    44821 atttttttcg atttggatgg aaccctcgtt gatagttcta tcgggattca caatgccttt
    44881 acctatacct ttaaagagct gggggtgcct agccctgatg ccaaaactat tcgtggtttt
    44941 atgggaccac ctctcgaaag tagttttgcg acctgcctgt ccaaagacca aatttctgaa
    45001 gccgtgcaga tatatcgttc ttactataag gcaaaaggca tctatgaagc tcaactcttt
    45061 cctcagatta tagacttgct tgaggagtta tcgagcagtt atccactcta catcaccacg
    45121 acaaaggata catctactgc tcaagacatg gcaaaaaact tggaaatcca tcatttcttt
    45181 gatggcattt atggttctag ccctgaagca ccccataagg cagatgtcat tcaccaagcc
    45241 ttgcagacac atcaactagc accagaacaa gccatcatca tcggagatac caagtttgat
    45301 atgctgggag ctcgagaaac aggtattcag aaattggcca tcacttgggg atttggagag
    45361 caagcagatc tactaaacta tcaacctgat tatatcgctc acaaaccctt agaagttttg
    45421 gcgtattttc aatagcatag actgggtaac aattccattt cagaagaaaa tgaagtaata
    45481 ctcaatgaaa atcaaagagc aaactaggaa actagctgcg ggctgctcaa aacactgttt
    45541 tgaggttgca gatagaactg acgaagtcag ctcaaaacac tgttttaagg ttgtggatgg
    45601 aactgacgaa gtc
//
LOCUS       DAVDHC010000015        45379 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVDHC010000015 DAVDHC010000000
VERSION     DAVDHC010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.015"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            1..985
                     /locus_tag="VUR43_001146"
                     /pseudo
     CDS             1..985
                     /locus_tag="VUR43_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1113..1316)
                     /locus_tag="VUR43_001147"
     CDS             complement(1113..1316)
                     /locus_tag="VUR43_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5412840.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1309..2391)
                     /locus_tag="VUR43_001148"
     CDS             complement(1309..2391)
                     /locus_tag="VUR43_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET5412841.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2517..3299)
                     /locus_tag="VUR43_001149"
     CDS             complement(2517..3299)
                     /locus_tag="VUR43_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET5412842.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3299..4642)
                     /locus_tag="VUR43_001150"
     CDS             complement(3299..4642)
                     /locus_tag="VUR43_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET5412843.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRYGEIYTTYKMILDAIRKVPT
                     ATVLLNGDSPLFYKPAIPNPVEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLSKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4741..6057)
                     /locus_tag="VUR43_001151"
     CDS             complement(4741..6057)
                     /locus_tag="VUR43_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET5412844.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6250..7476
                     /locus_tag="VUR43_001152"
     CDS             6250..7476
                     /locus_tag="VUR43_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET5412845.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GIVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7675..9249
                     /locus_tag="VUR43_001153"
     CDS             7675..9249
                     /locus_tag="VUR43_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET5412846.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            9514..10302
                     /gene="codY"
                     /locus_tag="VUR43_001154"
     CDS             9514..10302
                     /gene="codY"
                     /locus_tag="VUR43_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET5412847.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10302..10877
                     /locus_tag="VUR43_001155"
     CDS             10302..10877
                     /locus_tag="VUR43_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET5412848.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10959..11044
                     /locus_tag="VUR43_001156"
     tRNA            10959..11044
                     /locus_tag="VUR43_001156"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10993..10995,aa:Leu,seq:aag)
     gene            11327..12457
                     /gene="ugpC"
                     /locus_tag="VUR43_001157"
     CDS             11327..12457
                     /gene="ugpC"
                     /locus_tag="VUR43_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET5412849.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(12580..12750)
                     /locus_tag="VUR43_001158"
     CDS             complement(12580..12750)
                     /locus_tag="VUR43_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412850.1"
                     /translation="MEIKEQTRKLAVSYSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEYKEHHNIDV"
     gene            12958..13716
                     /locus_tag="VUR43_001159"
     CDS             12958..13716
                     /locus_tag="VUR43_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET5412851.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKFAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13803..14315
                     /locus_tag="VUR43_001160"
     CDS             13803..14315
                     /locus_tag="VUR43_001160"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET5412852.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            14497..15441
                     /locus_tag="VUR43_001161"
     CDS             14497..15441
                     /locus_tag="VUR43_001161"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET5412853.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            15450..16127
                     /locus_tag="VUR43_001162"
     CDS             15450..16127
                     /locus_tag="VUR43_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET5412854.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELFFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            16225..16983
                     /locus_tag="VUR43_001163"
     CDS             16225..16983
                     /locus_tag="VUR43_001163"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET5412855.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            17021..18526
                     /gene="lytC"
                     /locus_tag="VUR43_001164"
     CDS             17021..18526
                     /gene="lytC"
                     /locus_tag="VUR43_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET5412856.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            19023..19541
                     /locus_tag="VUR43_001165"
     CDS             19023..19541
                     /locus_tag="VUR43_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET5412857.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19671..20177
                     /locus_tag="VUR43_001166"
     CDS             19671..20177
                     /locus_tag="VUR43_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET5412858.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            20177..20347
                     /locus_tag="VUR43_001167"
     CDS             20177..20347
                     /locus_tag="VUR43_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412859.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            20379..21611
                     /gene="clpX"
                     /locus_tag="VUR43_001168"
     CDS             20379..21611
                     /gene="clpX"
                     /locus_tag="VUR43_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET5412860.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21620..22207
                     /locus_tag="VUR43_001169"
     CDS             21620..22207
                     /locus_tag="VUR43_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET5412861.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            22218..22598
                     /locus_tag="VUR43_001170"
     CDS             22218..22598
                     /locus_tag="VUR43_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET5412862.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVVRLPRDVKVEIEVIAEIG"
     gene            22650..23540
                     /gene="rapZ"
                     /locus_tag="VUR43_001171"
     CDS             22650..23540
                     /gene="rapZ"
                     /locus_tag="VUR43_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET5412863.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            23537..24514
                     /locus_tag="VUR43_001172"
     CDS             23537..24514
                     /locus_tag="VUR43_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET5412864.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            24511..25422
                     /gene="whiA"
                     /locus_tag="VUR43_001173"
     CDS             24511..25422
                     /gene="whiA"
                     /locus_tag="VUR43_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET5412865.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGNIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(25510..26637)
                     /locus_tag="VUR43_001174"
     CDS             complement(25510..26637)
                     /locus_tag="VUR43_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5412866.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIETIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(26791..27741)
                     /locus_tag="VUR43_001175"
     CDS             complement(26791..27741)
                     /locus_tag="VUR43_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HET5412867.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPNDWHRNEPKV"
     gene            complement(27890..28666)
                     /locus_tag="VUR43_001176"
     CDS             complement(27890..28666)
                     /locus_tag="VUR43_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5412868.1"
                     /translation="MKVENKEIFANNLSFYMEQKGVDRNTLCADLDLKYTTVRDWLKG
                     ITYPRIGKIELLANYFNINKSDLIENKISTAQPSDSLLEEITNTARKLNTENKKIVLR
                     TSEELLESQKNEEETKVNEVSEVISLYKVEVVSETAAASGFNYGFGYDDTDRETIEVD
                     EQPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAVIAYGDRSYFKKIYTE
                     NGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            28820..28957
                     /locus_tag="VUR43_001177"
     CDS             28820..28957
                     /locus_tag="VUR43_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412869.1"
                     /translation="MMEHIIKSLATKDTATVILVLGLTREARLWHKQILEHKRKLQNK
                     K"
     gene            complement(29266..29562)
                     /locus_tag="VUR43_001178"
     CDS             complement(29266..29562)
                     /locus_tag="VUR43_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412870.1"
                     /translation="MDFNQIAITFLTSCVPAFLVYLTNKHQTNAKIKELKTQSENELQ
                     RLEKEHELKLDALKQSQQVDIASKFFTGEVDIKNITKAINGIAELQKAVDKLSK"
     gene            29629..29766
                     /locus_tag="VUR43_001179"
     CDS             29629..29766
                     /locus_tag="VUR43_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412871.1"
                     /translation="MTQKALAEKAGISPNTIRNIKTERISFKNMCKIADALEVSLDEF
                     R"
     gene            29779..29985
                     /locus_tag="VUR43_001180"
     CDS             29779..29985
                     /locus_tag="VUR43_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001171134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412872.1"
                     /translation="MQKMTLKTLRTLKNWRQSDAAEAVNVSVDTWGHWERGITEPSVS
                     KAYQIANVFEVSVDDIIFLPDIAV"
     gene            30062..30598
                     /locus_tag="VUR43_001181"
     CDS             30062..30598
                     /locus_tag="VUR43_001181"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412873.1"
                     /translation="MEEFIDALEKEKDHLEKVIKVVSAGGKFLRLPYQKKSRSISEYL
                     KLISQNLDRLSCLYNQRGERMTDRELFELPEDYVESTGLDKITFEVPFELFTKILKGY
                     GHKLAWEDYRQIKIHPSTRTKKTVGQCQFLFSIWMNDHLKPAIKPSKELQKEPVRKTK
                     RLKRLRKLAQNLLHRMKG"
     gene            complement(30925..31116)
                     /locus_tag="VUR43_001182"
     CDS             complement(30925..31116)
                     /locus_tag="VUR43_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412874.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDELQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            31235..31378
                     /locus_tag="VUR43_001183"
     CDS             31235..31378
                     /locus_tag="VUR43_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412875.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     RTV"
     gene            31375..31545
                     /locus_tag="VUR43_001184"
     CDS             31375..31545
                     /locus_tag="VUR43_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412876.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAVEARLNQKADQLKLDDVD
                     LEIISSRLEKVI"
     gene            complement(31538..31777)
                     /locus_tag="VUR43_001185"
     CDS             complement(31538..31777)
                     /locus_tag="VUR43_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412877.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMASPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            31895..32167
                     /locus_tag="VUR43_001186"
     CDS             31895..32167
                     /locus_tag="VUR43_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412878.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            32164..32379
                     /locus_tag="VUR43_001187"
     CDS             32164..32379
                     /locus_tag="VUR43_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412879.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEKRWNIFTW"
     gene            32358..32546
                     /locus_tag="VUR43_001188"
     CDS             32358..32546
                     /locus_tag="VUR43_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412880.1"
                     /translation="MEYIYLVTIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMNL
                     RNSDKQFTYDVEPPEGLK"
     gene            32558..32899
                     /locus_tag="VUR43_001189"
     CDS             32558..32899
                     /locus_tag="VUR43_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412881.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDNRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            32900..33130
                     /locus_tag="VUR43_001190"
     CDS             32900..33130
                     /locus_tag="VUR43_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412882.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELQRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            33144..33866
                     /locus_tag="VUR43_001191"
     CDS             33144..33866
                     /locus_tag="VUR43_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET5412883.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNSGQFKKGNRPPNYVPVGTINYTTDGYPKEKIGEPNQW
                     VLKHRKVWEEHHGPIPKGYSIVFLDGDKTNYDISNLACLSKNEIVRMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            33859..34341
                     /locus_tag="VUR43_001192"
     CDS             33859..34341
                     /locus_tag="VUR43_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HET5412884.1"
                     /translation="MASLYELTGQFLTIYQMDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            34341..34700
                     /locus_tag="VUR43_001193"
     CDS             34341..34700
                     /locus_tag="VUR43_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412885.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            34700..35185
                     /locus_tag="VUR43_001194"
     CDS             34700..35185
                     /locus_tag="VUR43_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412886.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            35148..36341
                     /locus_tag="VUR43_001195"
     CDS             35148..36341
                     /locus_tag="VUR43_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HET5412887.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFRNYESYISNLPNFFRWEDIEKIENATENNGFETKF
                     YPVTVKAGNPEKLAEFRQLNLVTVGDKTAMAKQSFGRKTFERYLNQTGVIVDFPKLKP
                     VNADTPLMLKLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            36360..36677
                     /locus_tag="VUR43_001196"
     CDS             36360..36677
                     /locus_tag="VUR43_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412888.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            36677..37504
                     /locus_tag="VUR43_001197"
     CDS             36677..37504
                     /locus_tag="VUR43_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET5412889.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            37524..38027
                     /locus_tag="VUR43_001198"
     CDS             37524..38027
                     /locus_tag="VUR43_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412890.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALKRKAVGSYYNLVISVTKGKDGREFRNYDLEEEAQPLTEADI
                     DDDDLPF"
     gene            38200..39021
                     /locus_tag="VUR43_001199"
     CDS             38200..39021
                     /locus_tag="VUR43_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HET5412891.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLINFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKYLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPTPLPEKEMMRTIESMIKKDRR"
     gene            39024..40367
                     /locus_tag="VUR43_001200"
     CDS             39024..40367
                     /locus_tag="VUR43_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET5412892.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSNQAMLDGMET
                     FFSERSYNPVIEYMEKAAEKWDGRKRIDRMLQVYLGAEDIPLISKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFIIARTTNQTEYLKDKTGER
                     RFLPIMADSRQQKKHPMEIEPETIEQIWGEAVAIYRAGADLMFDEDTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            40661..40813
                     /locus_tag="VUR43_001201"
     CDS             40661..40813
                     /locus_tag="VUR43_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412893.1"
                     /translation="MSYTVTLYFDNMVDETHFFKKEGDAAKCKAQIESKYRGDRMYKV
                     KMEEME"
     gene            40813..41151
                     /locus_tag="VUR43_001202"
     CDS             40813..41151
                     /locus_tag="VUR43_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412894.1"
                     /translation="MSYDLEILAKIESGDYICIAEPRYSSPTYNLGKMFRVAMDWDFD
                     QGTIYNVADIFENIKRGITELERQPEKYVQYEPANKWGTINDALYVLRSLRDCILEQD
                     IDTKYLYVRW"
     gene            41302..41616
                     /locus_tag="VUR43_001203"
     CDS             41302..41616
                     /locus_tag="VUR43_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412895.1"
                     /translation="MEELKKKVNAVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMARVIIAVYLIYR
                     GN"
     gene            41618..42121
                     /locus_tag="VUR43_001204"
     CDS             41618..42121
                     /locus_tag="VUR43_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET5412896.1"
                     /translation="MNVQRLIEKYKKLEGVWDAEGAELARQIFLEDLKQLDEQKPVKV
                     PQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLNGYEIEKE
                     KRYFVKIKGNIKENMLVYGELLKRYFFTKRFSLDDVIYSHTRKELEDANFGWVFDCPG
                     IEIEEVE"
     gene            42121..42186
                     /locus_tag="VUR43_001205"
     CDS             42121..42186
                     /locus_tag="VUR43_001205"
                     /inference="COORDINATES: protein motif:HMM:NF021182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412897.1"
                     /translation="MEDEEIIGNIYENPELLEVNE"
     gene            42183..42497
                     /locus_tag="VUR43_001206"
     CDS             42183..42497
                     /locus_tag="VUR43_001206"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET5412898.1"
                     /translation="MRYFKILCIVLFASLLVACHQISSGTVVDKYIDEPHTTFIPVIN
                     GKSSVLVPTRTKRKYILVVSGFTGNKQVEERFEVTANEYKHYEIGNTFIQDAVLENKE
                     DK"
     gene            42617..43078
                     /locus_tag="VUR43_001207"
     CDS             42617..43078
                     /locus_tag="VUR43_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET5412899.1"
                     /translation="MNKAKELLKELQNLDMDIQSRIDEINELEAGLLSSPKWSDVKVQ
                     GGQARKVDDVYTQLVVMKEAIEQDTKEVINRKLQLGRMINRLKNPKHRTILRMTYINK
                     MYVDDICDSMRGISSPTYYRLKKQAVKELDIILSELIVNDSNCTGMKSKIC"
     gene            43103..43185
                     /locus_tag="VUR43_001208"
     tRNA            43103..43185
                     /locus_tag="VUR43_001208"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43134..43136,aa:Tyr,seq:gta)
     gene            43434..43913
                     /locus_tag="VUR43_001209"
     CDS             43434..43913
                     /locus_tag="VUR43_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HET5412900.1"
                     /translation="MAFFDYSKGGDGKLSGLRIKQKRFADEYIISGNATEAYKKAGYR
                     VSSDRVAGVEGHKLLKNPKIKSYIDERLKQLDSEKIADQQEVLSYLTSVMRGETQEQT
                     LISIGELGQTITDIDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            43891..45189
                     /locus_tag="VUR43_001210"
     CDS             43891..45189
                     /locus_tag="VUR43_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HET5412901.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRNLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWGNLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
BASE COUNT        14369 a         7948 c        10015 g        13047 t
ORIGIN      
        1 aaagatagag tttctcttga atacggcctc ccaagtcgta cgatacttct taactggcta
       61 gcacaataca ggaaaaacgg gtatactatt gttgagaaaa caagagggag agtacctaaa
      121 atgggacgta agccaaaaaa gagacctgaa gagaggacag aattagaata tcttcaagca
      181 gaaaatgagt acctgagagc ggagaatgcc atcctaaaaa agttaagaga actccgattg
      241 aaggaggaaa aagagaaaga agaaagacag aaattgttca agaattaatg actgagtttt
      301 cgttagatct tcttctaaaa gccattaaac tagctcgttc gacctactac tatcacttga
      361 aacagctaga taaaccagat aaggaccaag agcttaaagc tgaaattcaa tccatcttta
      421 tcgaacacaa gggaaattat ggttatcgtc ggatttattt agaactaaga aatcgtggtt
      481 atctggtaaa tcataaaaga gttcaaggct tgatgaaggt actcaattta caagctaaaa
      541 tgcgacagaa acgaaaataa aggagacgtt ggtaagaagg cagagaatct cattcaaggc
      601 caatttgaag gctctaaaac aatggaaaag tgctacacag atgtgacaga atttgccatt
      661 ccagcaagta ctcaaaagct ttacttatca ccagttttag acggctttaa cagcgaaatt
      721 attgctttta atctttcttg ttcgcctaat ttagaacaag tacaaacaat gttggaacag
      781 gcattcacag agaagcacta tggtggagtc cttctttggg attctgaaat cggaaatgtt
      841 ttatggctat gagaaaacat ttaaatcact taatcaattg gaacaagcta ttgtagacta
      901 tattgattac tacaacaata aacgaattaa ggtaaaacta aaaggattta gttctgtgca
      961 gtacagaact aaatcctttg gataaattaa ttgtctaact tttggggggc agtacatttt
     1021 aacacttgat aatatgcgtt ttattgtggg aagattttcc tcattttcta gtgaaattga
     1081 actttttcta acatcttttg atagatgact tcttaatcaa ttatcatttc cattgttgtt
     1141 tcttggggtt tcatcccttg tctttgataa aagcggagag caccctcgtt atcattccag
     1201 acacttaggg ttagattatt gcagccaatt tctttagcat aatagcagaa aaatgacaat
     1261 aaaatagccc ctagatattt tgaaaggaaa gcataggggc tatatagttt aatcaaaata
     1321 aagcaaatct ttgctggtgc ttgtaaagag gtcgaagcca tccttggtaa caacaccgca
     1381 gtcttcaata cgaacaccga ctttaccagg gatatagata cctggttcaa cagagaagca
     1441 catgccttct tcgatgacca tgtcgtttcc ttccatgata gatgggaatt catggacatc
     1501 cataccgata ccatgcccga gacggtggtt gaagtactca ccataaccag ctttttcgat
     1561 gacctcacgg gcagcgcggt ccacttcatg agcagtcaca cctggcttga taaagtcaag
     1621 agcagcttgt tgggcttcaa gagtcaagtt gtaaatatct ttcttgaatt ggtctggttt
     1681 gccgacagcg actgtacgag tcatatctga cgcatagcca ttgaccagaa cacccaggtc
     1741 aaagaggaga agagcatcat tttcaacctt attagctgct ggaatgccgt gtggattcgc
     1801 agcattatca ccagtcaaga ccatggtatc aaagctcatt tcgtaacctt cacgtttcat
     1861 ggcaaagtca atttgtgcga tgatatctgt ctcagtctta tcaagagaaa tattgtcaaa
     1921 accaacatga acagccttgt cagcataaag acctgcaacc atcatttttt gcacttcatc
     1981 agctgatttg atgaggcgca tgcgttggat acgaggagtg aggttgtcaa actcagcagt
     2041 ctcaaaaact gttttcaaac catggtattt ggtcaagatg agattgtcaa actcaacagc
     2101 gacacgtttg aagtcaagtt gtggaagagc atgtttgatt ttttgccatg gattttcaga
     2161 atcgacatag cccactactg ggaaggaaac ggtgctactt gcacgttcta cttcaagagc
     2221 tgggacaaag aggagaggtt cctgatccgc taggacaaag aggaacattt ggcgttcatg
     2281 gggatcactg taaaaaccag tgaggtaatt gattgtgacg gggtcagata cgacagcgac
     2341 gtctagtttt tctgattcaa gatatgttag gatttgttgt aatttagaca tatgctacct
     2401 tctttctacc cctctatttt ggcaaaaaat gagagaaaat gcaagggaga agggtaaaag
     2461 aaaagacaaa aaactccgac aagataacgg agttctttga tatcattttc ctttgtttaa
     2521 gaaaagtcag ccttgctttt gacgtcactg tactcttcag cgatttcttg gctgagaatg
     2581 tcctcatagg cagggagttg gatgtcctga ccatatttct tcttgagggc agtagtaact
     2641 aggcgataag ccagattggc attacgagag aggataggcc cgtggaagta ggaaccaaag
     2701 acattcttat aatgaacccc ttcaccgacc ttttcttcgt tgtttccatt tccatagaca
     2761 acctgtccca gcggtttttg gtcatcagag aggaaggtac gaccttggtg attttcaaat
     2821 ccatagtagg tttcatcgaa atcttcattg tgaatcttga tgtcaccgat aaaacggtta
     2881 ttggtctggt tgagcgtgta gtgtcccatg acccctagcc cttcgatacg ttttcctgaa
     2941 gcttcaacat aatattgacc caatagttgg aaaccaccgc agatagccag aactacaccg
     3001 tcgttttgga tgtagttgtc aatgctctct tttttagcag gtaggtcgtc tgcaatgata
     3061 ctttgttcaa agtcttgacc accaccgaaa aaggcgatgt cgtagtgatt ttcatcaaag
     3121 tcatcatgga gagaaacgat gtcaacggtc acatgggctc ccagtttttc agccacatac
     3181 ttgagcatga ggatgtttcc attgtccccg taggtattca tgagatttcc gtagaggtgg
     3241 gcaatgttga gctgataggg gtaattgcta tcttttgagg aaagtgaagt ataaaccatt
     3301 agttcatctc ctttctaaca atctgacgac tagccagcag ttcacgaaat tccagcatgg
     3361 cagtataagt tgccagaata taggcatgct tgcagtcttg attctcaatg gtcttgagaa
     3421 cttgctccag attactcgtt tcagtgattt tctcagctgg atagccagtc actcggaggc
     3481 gacgagcgat ttcagaatga cgaacaccgc cagcgttgat ttcaggaatg tccatgtcag
     3541 tgatttgttc aaagtctgca tcccagatcc agctagtgtc aattccatct gcatagttgg
     3601 cattaaggag gacagatagg ctaaatggat aaggtgctag tttgatcatt tcgatagctt
     3661 gggttgcacc gactggattt ttactcaaga caagggtaca ttctttgtca ccgatatgaa
     3721 aggtttcttg gcgtccaaag acagcacggc tcttgtcaaa tccctgtttg atgagttgcg
     3781 aatcggcacc taggaaacgg gcgatggcca cagcagctag ggcgttatag atattataga
     3841 gcccgccgat ttggataccg tattcttggc cgtctatgac aaagcgagag cgattgttgg
     3901 tcaactcaac cagttttgtc aaacgatagt cgagatcagg acgtttgcat ccacaacctt
     3961 cacagatata ggcacccaag tttgcatagg tattatgctc atatttgagg atgccttggc
     4021 agtcaggaca gaggattcct tcggtattat agtgagccag ctgggctgga cctttctcca
     4081 agtcaaaacc aaaatactct acaggatttg gaatagctgg cttgtagaaa agtggactgt
     4141 ctccattaag gagaacagtg gcagtaggca ccttacgaat ggcatccaaa atcatcttgt
     4201 aagttgtgta aatctcacca tagcggtcca tctggtcacg gaaaatatta gtaataacaa
     4261 ataagcttgg ctggatatag tcacagatac gagatagact ggcctcgtcg atttctagga
     4321 cggcaatatt tttcccagtt ttagaagatt tggctgttaa gaaggttgtc gcaattcctg
     4381 taatcatgtt ggcaccgctt gggttggtca gaacttgacc ataaacttct tttaaaatac
     4441 cgacagtgag ggcagttgtc aaggtttttc cgttggttcc agtgaccacg acaatctcgt
     4501 agttcttagc taggttttgt aaaatatctt tatcaaattg aagggcgact ttacctggga
     4561 gcgtacttcc acggccaaga cggcttaaaa tgaagtggga agaacgccca gcaagaaggc
     4621 ccaaagtagt ttttaagttc atgtttctat tatatcataa aagaggagaa agacagattt
     4681 gagattccgc agaagtaaaa acagcccaaa gagggctgtt cgatacgatt aaatctcaac
     4741 ttaaatcgca aacaagtcat tcaagttctc agccaaggtt gggtgagtga agatttgttt
     4801 tgtgaagtaa gtgtaaggaa tcttgttgtc catagcaaca gtgatgatgt tgatgatttc
     4861 ttgagaacct tctgagaaga tgcttgctcc aagaatttct tttgtttcag tattgacaac
     4921 agctttgaag gcaccgcgaa ggtctccatt tacgtgacca cgaggcattg ctgcaacggg
     4981 gatttcctta acagcgtatg gaagtttcaa atcagctgct tggctttcag tcaaaccaac
     5041 ttgtgaaagt gcaggtgtga tgaacatagt atttggcaca ttgagacggt cttcaagtgt
     5101 gtagctgcca tctccagcaa ggtagctgta aacaacacgg aagtcatcaa gtgaaatgta
     5161 agtaaattga aggccaccgt tgacatctcc aactgcaaag acaccaggaa cgtttgtttg
     5221 acagtgtttg tctactttaa tagcaccacg ttcagttagt tcaatatctg tattttcaag
     5281 ttgaagtggt tctacatttg gtttgcgtcc agttgcgtag agaagggcgt cgaaacggta
     5341 agtttcgtct tcagttacga caagcacttg gtcaccatcg tttttaattt cagtagtatg
     5401 gatattttga agcaattcaa tgccatcttc ttccatgtat tgtttagcaa gagctgcgat
     5461 ggaaggttct gcacgaggaa ggaaagtatc caaggcatct aggactgtga ccttgcttcc
     5521 aagtttgttg taaaggccgg caaattcaag accgatattt ccgccaccaa ggattccaag
     5581 tttttcaggt aatttgtcca agttttggat acctgttgag tcaaagatgt ttttgcttgt
     5641 agcaagtcca ggaattggca agacgtttga aacagcacca gtgttgatga cgatagtttc
     5701 agcagtcaat tcttgttttt catcaccagc ttggatttcg atgactttat ttgaaaggaa
     5761 gtgagcttca gcatcaaaga tatcgacgcc agtaccagca acagtcgtat agtttttacc
     5821 gttgaggcga ccagtgatcg tgtttttagt agcaatcact tcttcaaaag acaagtcctt
     5881 ttcagcagca actagcaagg ttttagttgg gatacaacca atgttgatac aagttccacc
     5941 gtacatagcc ttgctgcgtt caacgagggc aacttttttg ccagctgaag ccaatttacc
     6001 tgctagtgtt ttaccagctt taccaaatcc aataacaatt aaatcgtatg ttaacattta
     6061 tcttcctcct attcgaattt cattctagca caagaaaaaa acttttgcac aattctgcta
     6121 cggaaaagac agaaaaagat aaaaacgctt tccagacaaa aaactagtaa ttttttgaca
     6181 agcttgataa actaaaatcc tatctatttt tatataagaa agaataaatg ttcgaaaata
     6241 ggaggtttta tgaaatcgaa tcgttatatt attgcctttg ctggggtcat tttacactta
     6301 atgctgggtt cgacttatgc ttggagtgtt tatcgtaacc ctattattga aaaaacggga
     6361 tgggatcagg cttctgttgc cttcgccttt agtctagcaa tcttttgttt gggcttatcg
     6421 gctgcattta tggggcgttt ggtagaaaaa tttggtccga aagtcatggg gagtctatct
     6481 gcttttctat acgcaggtgg aaatatctta acaggatttg caatagaccg tcaggaactg
     6541 tggttgttgt atctagctta tggcatttta ggtgggcttg gtttgggagc aggctatatt
     6601 acccctgtgt caacgattat aaaatggttt cctgataaac gtggtctcgc aacaggttta
     6661 gcgattatgg ggtttggttt tgcttcttta ttgactagtc ccatagcgca acacctcatc
     6721 gcaggggtag ggattgtaga aactttttat attttaggag caagttactt tattatcatg
     6781 ctcctagctt cacaattcat taagcgtcca aatgagcaag agcttgcaat tttatcttct
     6841 tcagggaaag aaaaaacagc ctctttgacg caaggaatgg ctgcaaatca ggctctaaaa
     6901 agcaatcggt tttatatgct ttggattatt ttctttatca acatagcttg tggtttaggc
     6961 ttaatttcag cggcatcgcc aatggcacag gagatggctg gcttgtctac aagtcatgca
     7021 gcagtaatgg tgggtgtttt ggggattttc aatggatttg gtcgcttgct ctgggcgagt
     7081 ttgtctgact atatcggtcg ccctctaacc tttagtatat tactgcttgt caatcttttc
     7141 ttttctctct cactttggct ctttacagat tccgttttat ttgtagttgc tatgtctatt
     7201 ttgatgactt gctatggagc tggtttttct ttgattccag cttatctcag tgatattttt
     7261 ggaaccaagg aattggccgc tctgcatggt tatattttaa cagcttgggc aatggctggt
     7321 ttagcgggac ctattttatt agcagagact tataaaatgg ctcattcgta cacacaaacc
     7381 ttgttcgttt ttctcatttt atacagtatc gccttggctt tgtcttatta tctaggtcgt
     7441 tcaatcaaaa aagaaagtca aaaaccgctt acatgatttt ctgtagaaat ggggctatct
     7501 tttgctctgg tcttgtgtta tactagatag gttgcaaaga aaacagtact tttcttttgt
     7561 ggaaaagaag caacacgatt ttatatctag ttatatgaaa atacgtcata aaaagaaaag
     7621 tataaactaa gccctatagg gtggcttcgc accaccttta gaaagaagaa taacgtgaaa
     7681 tttaatgaat taaacttgtc tgctgatttg ctagcagaaa ttgaaaaagc tggttttgta
     7741 gaagctagtc ctatccaaga acaaactatt cctttggccc ttgaaggcaa ggatgttatc
     7801 ggtcaagctc agactggtac aggaaaaact gcagcctttg gcttgcctac ccttgaaaaa
     7861 atccgtacag aagaagcgac tatccaagct ttggtcatcg ctccaactcg tgaactagct
     7921 gtccaaagtc aagaagaact cttccgcttt ggtcgtagta agggagtcaa agtccgttca
     7981 gtatatggcg gatcaagcat tgaaaaacaa attaaggctc ttaaatctgg tgcccatatc
     8041 gtggtgggaa ctccaggtcg cctcttggac ttgattaaac gcaaggcctt gaaattacaa
     8101 gacattgaaa cccttatcct tgacgaagcg gatgaaatgc ttaacatggg cttccttgaa
     8161 gacatcgaag ccattatttc ccgtgtacct gagaaccgtc aaactttgct tttctcagca
     8221 actatgccag atgccatcaa acgtatcggt gttcagttta tgaaagcccc tgaacatgtc
     8281 aagattgcgg ctaaggaatt gacaacagaa ttggttgacc agtactatat ccgtgttaag
     8341 gaacaagaaa aatttgacac catgactcgt ctcatggatg tggcacaacc agaactcgct
     8401 attgtatttg gtcgtaccaa acgccgtgtg gatgaattga ctcgtggttt gaaaattcgt
     8461 ggcttccgtg cagaaggaat tcatggcgac ctagaccaaa acaaacgtct tcgtgtcctt
     8521 cgtgacttta aaaatggcaa tcttgatgtt ttggttgcga cagacgttgc agcgcgtggt
     8581 ttggatattt caggtgtgac ccatgtctac aactacgata ttccacaaga tcctgagagt
     8641 tatgttcacc gtatcggtcg tacaggtcgt gctggtaagt caggtcaatc tattactttt
     8701 gttgctccaa atgaaatggg ttaccttcaa atcattgaaa acttgactaa gaaacgcatg
     8761 aaaggtctca aacctgcaag tgtagaagaa tccttccaat caaaaaaaca ggtagctctc
     8821 aagaaaatcg aacgtgattt tgcagatgaa accattcgtg ccaactttga gaaatttggt
     8881 aaggatgctc gcaaattggc tgctgagttt actccagaag aattggcaat gtatatcttg
     8941 agtctgacag tccaagaccc agatagcctt ccagaagtgg agattgcacg tgaaaaacca
     9001 ctaccgttta aaccatcagg taatggtttc ggtggtaaag ctaagggagg tcgtggaggc
     9061 cgtcgtgggg acgaccgtcg agagcgtgat cgtcgtggca atggtcgccg tgatgagttc
     9121 aaaaaaggaa gtcgtggcaa cgatcgtttt gataaggaaa aacgttaccg taaggataat
     9181 aaaaaaccac gcaatacttt aagcgaaaag caaacaggct ttgttattcg taacaaaggt
     9241 gataaataag aaaaagcggt tcaaaatgaa tcgctttttt atataaggag accgaatgtg
     9301 aaaaagacaa ataaaattat tatattatct tttataatat tataatacac aaaaataggc
     9361 gacttgtcaa tagaaaagga acaatttaat taaaaatatt ctggttttta attaaattgt
     9421 aagtcaatgc aagtcaataa ggaattttca gataattatt gaaaaagaga cgtttttatg
     9481 ttataatgat agcgattaaa ttcgaggtga aaaatggcac atttattaga aaaaactaga
     9541 aaaattacat caattttgaa acgctcagag gagcagttgc aggatgagct cccttacaac
     9601 gctattacgc gtcagttagc ggatattatt cattgcaatg cctgcattat caatagtaag
     9661 ggacgtctgc ttggctattt tatgcgttat aaaacaaata cagatcgcgt agagcaattc
     9721 ttccaaacta agattttccc agatgactac gttcaagggg ctaatatgat ttacgaaaca
     9781 gaagcaaact tgcctgttga gcatgatatg agtattttcc ctgttgagag tagagatgat
     9841 tttccagatg gcttgacgac tattgcaccg attcatgtat cggggattcg ccttggttct
     9901 ttgattattt ggcgtaatga taaaaaattc gaagatgagg acttggttct tgttgagatt
     9961 gccagtaccg ttgttgggat tcagcttctt aacttccaac gtgaagaaga tgagaaaaat
    10021 attcgtcgtc gtactgctgt caccatggcg gtcaataccc tttcttactc cgaactccgt
    10081 gctgtttcag caattttagg ggaattaaat ggaaatgaag ggaagttgac tgcgtcagtg
    10141 attgcagatc gtatcggaat cactcgctct gtgattgtca atgctcttcg taaacttgag
    10201 tctgcgggga ttattgaaag tcgctcactt ggaatgaagg gaacctatct taaggtcttg
    10261 atttcagata tttttgaaga agtgaagaaa agagattact aatgacaaag gctttaattt
    10321 cgattgatta tacagaagat tttgttgctg atagtgggaa gctgacagca ggtgctccag
    10381 ctcaggcgat ttcggatgcc atcagcaagg taactcgatt agcttttgaa cgaggagatt
    10441 atatcttctt tactattgat gctcatgaag aaaacgattg tttccatccg gaaagtaagt
    10501 tatttcctcc tcataatctg attgggacga gtggacggaa tttatatgga gatttgggga
    10561 tcttttatca agagcatggt tcagacagtc gtgtcttttg gatggataaa cgccattact
    10621 cagctttttc agggactgac ctagatattc gtttgagaga gcgtagagtg tctaccgtta
    10681 tcttaacagg tgtcttgacg gatatctgtg tcctacatac agctatagat gcctataatc
    10741 taggatatga catcgagatt gttaaaccag ctgttgcttc catctggcct gaaaatcatc
    10801 aatttgccct aggtcatttc aaaaatacac tcggagctaa gttagtagat gaaaatctaa
    10861 atgaactttc tgagtaacct ggttggtgaa aatgaaaaaa tttgaaaaaa agtgttgaca
    10921 agcatcccaa aagttgatat actagtaaag taatcgatgc ggggatggcg gaattggcag
    10981 acgcgcagga ctaaggatcc tgtgaccgct ttaggtcgtg agggttcaag tccctctctc
    11041 cgcataggaa aagagttagc taaagctagc tcttttgtat ttctctaaaa aattagaatc
    11101 cagtcaaatg tagtggagaa tcagcgaaaa tatgggaaaa ctgatccttg tttctgcttt
    11161 tgtcatagaa gaataataaa gattatcttc ttcaaattct ccgatattct ctaaagtttt
    11221 gtgcaagttg cacagaactt ttttattttt ttggtcatct tgccatagaa atataaagcg
    11281 ttttcatcta taatataatt atcaaaagac aaaaggagtt cacctcatgg tagaattgaa
    11341 tcttaaaaat atttacaaaa aatatccaaa cagcgaacac tattcagttg aagatttcaa
    11401 cttgaacatc aaagataaag aatttatcgt tttcgtagga ccttcaggat gtggtaaatc
    11461 aactacactc cgtatgattg ctggtcttga agacatcaca gaaggtactg catctatcga
    11521 tggcgtggtt gtcaacgacg tagctccaaa agaccgtgat atcgccatgg tattccaaaa
    11581 ctacgctctt tacccacaca tgactgttta tgacaacatg gctttcggtt tgaaattgcg
    11641 taaatacagc aaagaagaca ttaacaaacg tgttcaagaa gcagctgaaa tacttggatt
    11701 gaaagaattc ttggaacgta aaccggctga cctttcaggt ggtcaacgtc aacgtgttgc
    11761 catggggcgt gcgattgtcc gtgatgcgaa agtattcttg atggacgaac ctttgtcaaa
    11821 cttggatgcc aaacttcgtg tatcaatgcg tgctgaaatc gctaaaattc accgtcgtat
    11881 cggagctaca actatctatg taactcacga ccaaacagaa gcgatgacac ttgcagaccg
    11941 tatcgttatt atgtcagcta ctaagaaccc tgctggtaca ggtactatcg gacgtgtaga
    12001 acaaatcggt actcctcaag aagtttacaa aaatccagtt aacaaattcg ttgcaggatt
    12061 catcggaagc ccagctatga acttcatcaa cgtgaaattg gttggtagcg aaattgtttc
    12121 tgacggtttc cgtttgaaag tgccagaagg agcattgaaa gttcttcgtg aaaaaggcta
    12181 cgaaggaaaa gaattgatct ttggtatccg tccagaagac gtgaatgcag aacctgcttt
    12241 ccttgaaaca ttcccagact gtgttgtaaa agcgactatc tctgtatcag aactgcttgg
    12301 ttcagaatct cacctttact gccaagttgg taaagacgag tttgttgcaa aagttgatgc
    12361 tcgtgactac ttgcaaacag gtgcaacagt tgagcttgga tttgacttga acaaagcaca
    12421 cttcttcgat gtagaaactg aaaaaacaat ctactaagaa taaataaaat tcaaagcact
    12481 acaagaaaag atatctcttt atcaattgta gtggagagat atcagttaat ctagggagag
    12541 aaacaaaatg cttctctcct ttttgctagg gaagtcatat tatacatcta tattgtgatg
    12601 ctctttatac tcttcgaaaa tctcttcaaa ccacgtcaac gtcgccttgc cgtacgtatg
    12661 attactgact tcgtcagttt tatctgcaac ctcaaagctg tactttgagt agcttacggc
    12721 tagtttccta gtttgctctt tgatttccat tgagtattat ttgtgggtac catctacaag
    12781 tgaagctata tgcgtaaact acgtgagcaa ttgaattcga actagagagg taataataaa
    12841 tttatgctat agttatggtg acttgtatgc ttttgattct agtttatcaa ataatagatt
    12901 agaattgtca gataatatca ttttgtgtta taatgaagaa aaaacagagg tgttcaaatg
    12961 tcagaagcag gtcataagtt tttagcaaaa ttggggaaaa aacgcttacg tccaggtgga
    13021 aagcgtgcca cagattggtt aattgcagaa ggaggatttt caaaagaaaa gagaatacta
    13081 gaggttgcgt gtaatagggg aactacagca attgagttgg cacagcgttt tggttgcaag
    13141 ataactgctg ttgatatgga tgctcaagct ttagaagtgg ctaaaaaatt tgctggaacg
    13201 gcaggtgttg ctcatttaat cagttttgaa agagcaaatg caatgaaact tccttatcaa
    13261 gatgctagtt ttgatattgt tataaatgaa gctatgctga ctatgcaagc cgatcaagct
    13321 aagaaaaaat gtgtaatgga atatctaagg gtattaaaac ctggaggtct tctcttgaca
    13381 catgatgtgc ttcttaagga agctaaagag tctatcagac aggaattatc acaagcaatt
    13441 catgtaaatg taggtccttt aactcaagat ggttgggaac aggtgatgat agaatcaggt
    13501 tattgtgatg tgaaagcatt gactggtgaa atgacattaa tgaaattatc gggtatgatt
    13561 tatgacgaag gtttgctagg aactttgaaa atttgtgtaa atgcttgtaa aaaggagaat
    13621 agaaagcagt ttttaactat gtataaaatg tttgctaaga ataaacagaa attgggcttt
    13681 attgcgatgg ctagttataa atcgtcaaaa cgttagataa ttattgaagt taacttttcc
    13741 ttttttcttt cttaaaaaat atgctataat agagagtaaa aaactttgaa agaaagaaaa
    13801 agatgaattt aaaagattac attgcaacaa ttgaaaatta tccaaaggaa ggcattacct
    13861 tccgtgatat tagtcctttg atggctgatg gaaatgctta tagctacgct gttcgtgaaa
    13921 tcgttcagta tgctactgac aagaaagtcg acatgatcgt gggacctgaa gctcgtggat
    13981 ttatcgtggg ttgtccagtt gcctttgagt tgggaattgg ttttgcgcct gttcgtaagc
    14041 caggtaaatt gccacgcgaa gttatttctg ctgactatga aaaagagtac ggtgtcgata
    14101 ccttgactat gcacgcggat gccattaagc caggtcaacg tgttcttatt gtagatgacc
    14161 ttttggcgac aggtggaact gttaaggcaa ctatcgagat gattgaaaaa cttggtggtg
    14221 ttatggcagg ttgtgccttc cttgttgaat tggatgaatt gaacggccgt gaaaaaattg
    14281 gtgactacga ctacaaagtt cttatgcatt attaatgaaa acagtcccta gggctgtttt
    14341 ctctacacta ggatataaaa atagactata actagttaga gaaaaactat aattgaaaac
    14401 tatatcttct tgcagtataa taaaaggact aagtgtttga gatttgtctt caaacatatg
    14461 caattattcc tgaaagagta cagttaggag agggttatgc cgattcgaat tgataaaaaa
    14521 ttgccagctg ttgagatttt acggacagag aatatctttg tcatggatga tcaacgtgct
    14581 gcccaccaag atatccgtcc tttgaagatt ttaattttaa atctcatgcc acagaaaatg
    14641 gtcacagaga cccagttgtt gcgccacttg gctaatacac ccctacaact ggatattgat
    14701 tttctctata tggagagcca ccgttctaaa acaactcgtt cagagcacat ggagaccttc
    14761 tataaaactt ttcctgaagt caaggatgag tattttgatg ggatgatcat cacgggtgct
    14821 ccagttgagc atttaccatt tgaggaagtg gactattggg aggaatttag acagatgctt
    14881 gagtggtcta agactcatgt ctattcgacc cttcatatct gttggggggc tcaggctggg
    14941 ctttatctgc gctatggtgt agaaaaatac cagatggaca gtaagctatc aggtatttat
    15001 cctcaggaca ccctaaaaga gggtcacctt ctatttagag gctttgatga tagctatgta
    15061 tcccctcatt cacggcacac ggagatttct aaggaagagg tcttaaacaa gaccaatctc
    15121 gagattttat cagaaggacc tcaggttggg gtttctattt tggccagtcg tgatttacga
    15181 gaaatttata gttttggtca tttggagtat gaccgtgata ccttggcaaa agagtatttt
    15241 cgagatcgtg atgcaggttt cgacccacat attccagaaa attactttaa agatgatgat
    15301 gttaatcagg taccttgtct ttgttggtct tcatctgcag ccctcttttt cagtaattgg
    15361 gtaaaccatg cggtctatca ggagacgcct tttgattgga gaaagataga agatgatgca
    15421 tctgcatatg ggtatttata agaggaatta tgacatattt agacgctttt aaatcaggta
    15481 ccttggtttt accgagtgcc ctgctcttgc attttaagga actctttcct tctagcgacg
    15541 attttctggt ttggcaattt ttctatttgc aaaatacgac aggcttagaa gaaatgtcgc
    15601 caagccagat tgctgaaagg attggcaagg aaatttcgga tgtcaaccag tccatttcta
    15661 atctgacgga aaggggactg ctccagtatc gtactatcga attaaatggc gaaattgaat
    15721 tgttctttga tgctagtttg gccttggaac gtttggatga cctgtttgga gcagttcgtt
    15781 caagttcaga ccagctaaca cctcaaaacc agctcaagga tttggtggaa accttccagc
    15841 aggagttggg acgattgttg acgccttttg agattgagga tttgaccaag acactaaagg
    15901 aagatggaac cagtgctgac ttgattaagg aggctcttcg tgaagctgtt ttgaatggaa
    15961 aaccaaactg gaagtacatt caggcaattt tgagaaactg gcgccatgaa ggaatcaaga
    16021 gtgtggctca aattgaggcc aagagagcag aaagagaagc aagcaatcct cagttgacac
    16081 aggtatctgc agatttcaga aatgccatgg atctctggaa ggattaatcc atgcaagtag
    16141 gcttgaaatc cgagtaagat ttgcaagctg tgtataattg tgatagaata aatagaaaat
    16201 aaattgaaaa aagaggtatg tgaaatgtca cgtaaaccat ttatcgctgg taactggaaa
    16261 atgaacaaaa atccagaaga agctaaagca ttcgttgaag cagttgcatc aaaacttcct
    16321 tcatcagatc ttgttgaagc aggtatcgct gctccagctc ttgatttgac aactgttctt
    16381 gctgttgcaa aaggctcgaa ccttaaagtt gctgctcaaa actgctactt tgaaaatgca
    16441 ggtgctttca ctggtgaaac tagcccacaa gttttgaaag aaatcggtac tgattacgtt
    16501 gttatcggtc actcagaacg ccgtgactac ttccatgaaa ctgacgaaga tatcaacaaa
    16561 aaagcaaaag caatctttgc gaacggtatg cttccaatca tctgttgtgg tgaatcactt
    16621 gaaacttacg aagctggtaa agctgctgaa ttcgtaggtg ctcaagtatc tgctgcattg
    16681 gctggattga ctgctgaaca agttgctgcc tcagttatcg cttatgagcc aatctgggct
    16741 atcggtactg gtaaatcagc ttcacaagac gatgcacaaa aaatgtgtaa agttgttcgt
    16801 gacgttgtag ctgctgactt tggtcaagaa gtcgcagaca aagttcgtgt tcaatacggt
    16861 ggttctgtta aacctgaaaa tgttgcttca tacatggctt gcccagacgt tgacggtgcc
    16921 cttgtaggtg gtgcgtcact tgaagctgaa agcttcttgg ctttgcttga ctttgtaaaa
    16981 taatcagtaa gtagcaaaag ctaggtggaa cagcattcag atgtctgtta cattttttat
    17041 aggagaggaa agattgaaaa taaaaattgg attagcaagt atctgtttac taggcttggc
    17101 aactagtcat gtcgctgcaa atgaaactga agtagcaaaa acttcgcagg atacaacgac
    17161 agcttcaagt agttcagagc aaaatcagtc ttctaataaa acgcaaacga gcgcagaagt
    17221 acagactaat gctgctgccc actgggatgg ggattattat gtaaaggatg atggttctaa
    17281 agctcaaagt gaatggattt ttgacaacta ctataaggct tggttttata ttaattcaga
    17341 tggtcgttac tcgcagaatg aatggcatgg aaattactac ctgaaatcag gtggatatat
    17401 ggcccaaaac gagtggatct atgacagtaa ttacaagagt tggttttatc tcaagtcaga
    17461 tggggcttat gctcatcaag aatggcaatt gattggaaat aagtggtact acttcaagaa
    17521 gtggggttac atggctaaaa gccaatggca aggaagttat ttcttgaatg gtcaaggagc
    17581 tatgatgcaa aatgaatggc tctatgatcc agcttattct gcttattttt atctaaaatc
    17641 cgatggaact tatgctaacc aagagtggca aaaagtgggt ggcaaatggt actatttcaa
    17701 gaagtggggc tatatggctc ggaatgagtg gcaaggcaac tactatttga ctggaagtgg
    17761 tgccatggcg actgacgaag tgattatgga tggtgctcgc tatatctttg cggcttctgg
    17821 tgagctcaaa gaaaagaaag atttgaatgt cggctgggtt cacagagatg gtaaacgcta
    17881 tttctttaat aatagagaag aacaagtggg aaccgaacat gctaagaaaa tcattgatat
    17941 tagtgagcac aatggtcgta tcaatgattg gaaaaaggtt attgatgaga acgaggtgga
    18001 tggtgtcatt gttcgtctag gttatagcgg taaagaagac aaggaattgg cgcataacat
    18061 taaggagtta aaccgtctgg gaattcctta tggtgtctat ctctatacct atgctgaaaa
    18121 tgagaccgat gctgagaatg acgctaaaca gaccattgaa cttataaaga aatacaatat
    18181 gaacctgtct taccctatct attatgatgt tgagaactgg gaatatgtaa ataagagcaa
    18241 gagagctcca agtgatacag acacttgggt taaaatcatc aacaagtaca tggacacgat
    18301 gaagcaggcg ggttatcaaa atgtgtatgt ctatagctat cgtagtttat tacagacgcg
    18361 tttaaaacac ccagatattt taaaacatgt aaactgggta gcggcctata cgaatgcttt
    18421 agaatgggaa aacccttatt attcaggaga aaaaggttgg caatatacct cttctgaata
    18481 catgaaagga atccaagggc gcgtagatgt cagcgtttgg tattaagcga tgatttgaaa
    18541 gagggatgtg atagtagcac cctctttttc tttgttttat gatagttcat cctcgagtaa
    18601 attcaagatc ttgctcggaa atgaagctta tatagtagat tgaatataga caaagacctt
    18661 gtgattggta aaacatttta gaaattcatt tacctttcct aatcgacttg gtttcatctt
    18721 atttcaatct attatagtat tggggaattt cttcaaacca catcagcttg gtcagttcta
    18781 cctgcgacct caaaacttgt gctttggtca agctgggttt agtttcctag tttgctgatg
    18841 gatttccatt gactataagc atccaaccct cttttttgtc ttctaaagaa ttcttaaatt
    18901 atcagtctat tgcaactttt ctcatataag ttctttgtct tgctattggt tttccttagt
    18961 agtatactaa ggtagtaatc attaagaagt ggttacaaaa aataatgaat gaggtaaaga
    19021 aaatggtaga attgaaaaaa gaagcagtaa aagacgtaac atcattgaca aaagcagcgc
    19081 cagtagcatt ggcaaaaaca aaggaagtct tgaaccaagc tgttgctgat ttgtatgtag
    19141 ctcacgttgc tttgcaccaa gtgcactggt atatgcatgg tcgtggtttc cttgtatggc
    19201 atccaaaaat ggatgagtac atggaagctc ttgacggtca attggatgaa atcagcgaac
    19261 gcttgattac actcggtgga agcccattct ctacattgac agagttcctt caaaatagtg
    19321 aaatcgaaga agaagctggt gaataccgta atgttgaaga aagcttggaa cgtgttcttg
    19381 ttatctaccg ttacttgtca gaacttttcc aaaaaggttt ggatgtcact gatgaagaag
    19441 gtgacgatgt gacaaacggt atctttgcag gcgctaaaac tgaaacagat aaaacaattt
    19501 ggatgcttgc agccgaactt ggacaagcac ctggtttgta agaaataagg aaacatagat
    19561 aaatctgtag gaaatttctt acagattttt tctattttgt aagctattcc aaaccagtct
    19621 ttttttgagt tttttgataa aatagtacta tcagtgaaaa ggatggaagc atgactaaga
    19681 aaatcgtagc tatttgggcc caggatgaag agggtgtgat tggtaaggaa aatcgtctgc
    19741 cttggcattt gccagcagaa ttgcagcact ttaaagaaac aactctgaat catgctatct
    19801 tgatggggcg tgtgaccttt gatgggatgg ggcgtcgctt gcttccaaaa cgggaaacct
    19861 tgattttgac gcgtaatccg gaagaaaaga tagatggggt tgctactttt caggacgtcc
    19921 agtctgttct tgactggtat caggctcaag aaaagaatct ctacattatc ggtgggaagc
    19981 aaatttttca ggcttttgaa ccttaccttg atgaagtgat tgtcactcac attcatgctc
    20041 gggtggaagg agatacctat ttccctgaag aacttgactt gtctcttttt gagacagttt
    20101 caagcaaatt ttacgccaaa gatgagaaga atccttatga ttttaccatc caataccgca
    20161 agagaaagga agtctaatgg aacggagttt atttggtcta ttcacggctt ttctgtgttt
    20221 catctgcttt ctggcaggag cacaagcttt tcgtaaaaag cgttacgggc tttctatcct
    20281 cctttggtta aatgccttta ccaatctggt caatagtatt catgcttttt acatgacctt
    20341 attttagata gaatgacagt atagaatgga aggaaatcat gtctacaaat agaaaaaatg
    20401 atatgatggt ttattgctca ttttgtggca aaaaccaaga agaagtacaa aaaataattg
    20461 ctggcaacaa tgcttttatt tgtaatgaat gcgtggagtt agctcaggaa atcattcgag
    20521 aagaattggt tgaggaagtc ttggcagact tgtctgaggt gccaaaacca attgaactcc
    20581 tccatatctt gaaccactat gtaattggtc aagatcgtgc caagcgtgcc ttggcagtgg
    20641 cggtttataa ccactacaaa cgcatcaatt tccacgatac acgcgaagag tcagaagatg
    20701 tggatttgca gaagtcaaac attttgatga ttggcccaac tggttcaggg aaaactttcc
    20761 ttgcccagac cttggctaag agcttgaatg taccttttgc tattgcggat gcgacagctc
    20821 tgacggaggc tggttatgtg ggtgaggatg tggaaaatat cctcctcaaa ctcttgcagg
    20881 ttgctgactt taacatcgaa cgtgcagagc gtggcattat ctatgtggat gaaattgaca
    20941 agattgccaa gaagagtgag aatgtgtcta tcacacgtga tgtttctggt gaaggggtgc
    21001 aacaagccct tctcaagatt atcgagggaa ctgttgctag cgtaccgcct caaggtggac
    21061 gcaaacatcc acaacaagag atgattcaag tggatacaaa aaatatcctc ttcatcgtgg
    21121 gtggtgcttt tgatggtatt gaagaaattg tcaaacaacg tctgggtgaa aaagtcatcg
    21181 gatttggtca aaacaataag gcgattgacg aaaacagctc atacatgcaa gaaatcatcg
    21241 ctgaagacat tcaaaaattt ggtattatcc ctgagttgat tggacgcttg cctgtttttg
    21301 cggctcttga gcaattgacc gttgatgact tggttcgcat cttgaaagag ccaagaaatg
    21361 ccttggtgaa acaataccaa accttgcttt cttatgatga tgttgagttg gaatttgacg
    21421 acgaagccct tcaagagatt gctaataaag caatcgaacg gaagacaggg gcgcgtggac
    21481 ttcgctccat catcgaagaa accatgctag atgttatgtt tgaggtgccg agtcaggaaa
    21541 atgtgaaatt ggttcgcatc actaaagaaa ctgtcgatgg aacggataaa ccgatcctag
    21601 aaacagccta gaggtgacta tggaacttaa tacacacaat gctgaaatct tgctcagtgc
    21661 agctaataag tcccactatc cgcaggatga actgccagag attgccctag cagggcgttc
    21721 aaatgttggt aaatccagct ttatcaacac tatgttgaac cgtaagaatc tcgctcgtac
    21781 atcaggaaaa cctggtaaaa cccagctcct gaactttttt aacattgatg acaagatgcg
    21841 ctttgtggat gtgcctggtt atggctatgc tcgtgtttct aaaaaggaac gtgaaaagtg
    21901 ggggtgcatg attgaggagt acttaacgac tcgggaaaat ctccgtgcgg ttgtcagtct
    21961 agttgacctt cgtcatgacc cgtcagcaga tgatgtgcag atgtacgaat ttctcaagta
    22021 ttatgagatt ccagtcatca ttgtggcgac caaggcggac aagattcctc gtggtaaatg
    22081 gaacaagcat gaatcagcaa tcaaaaagaa attaaacttt gacccaagtg acgatttcat
    22141 tctcttttca tctgtcagca aggcagggat ggatgaggct tgggatgcaa tcttagaaaa
    22201 attgtgagga aaagaaaatg gcaaaaacaa ttcatacaga taaggcccca aaggctatcg
    22261 gaccctatgt tcaaggaaaa atcgttggca accttttgtt tgctagcggt caagttcccc
    22321 tatcccctga aactggggaa attgtaggag agaatatcca agaacagaca gagcaagtct
    22381 tgaaaaacat cggtgctatt ttggcagaag caggaacaga ctttgaccat gttgtcaaaa
    22441 caacttgctt cttgagcgat atgaacgact ttgttccttt taatgaggtt taccaaacgg
    22501 ccttcaaaga ggaattccca gctcgttcag ctgtggaggt agttcgtctt cctcgtgatg
    22561 taaaagtcga aattgaagtc atcgcagaga ttggataagc tagttgaagt ttggtgttgc
    22621 cagacttctt ttgatataag gagaaaaaga tgacaaagaa acaacttcac ttggtgattg
    22681 tgacagggat gagtggcgca gggaaaactg tagccattca gtccttcgag gatctaggtt
    22741 atttcaccat tgataatatg ccgccagctc tcttgcctaa gtttttgcag ctggttgaaa
    22801 ttaaggaaga caatcctaag ttggccttgg tagtggatat gcgtagccgt tctttctttt
    22861 cagagattca agctgttttg gatgagttgg aaaatcaaga tggtttggat ttcaaaatcc
    22921 tctttttgga tgcggctgat aaggaattgg tcgctcgtta caaggaaacc agacggagtc
    22981 acccactagc agcagacggt cgtattttag atggaatcaa gttggaacgt gaactcttgg
    23041 cacctttgaa aaatatgagc caaaatgtgg tggatacgac tgaactcact ccacgtgagc
    23101 tgcgcaaaac ccttgcagag cagttttcag accaagaaca agcccagtct ttccgtatcg
    23161 aagtcatgtc tttcggattt aagtatggaa tcccgattga tgcggacttg gtctttgatg
    23221 tccgtttctt gccaaatccc tattatttac cagaactgag aaaccaaacg ggtgtggatg
    23281 aacctgttta tgattatgtc atgaaccatc ctgagtcaga agacttttat caacatttat
    23341 tggccttgat tgagccgatt ctgccaagtt accaaaagga aggtaagtcc gttttgacca
    23401 ttgccatggg atgtacgggt ggacaacacc gtagtgtggc atttgctaaa cgcttggtgc
    23461 aggacttatc caagaattgg tctgttaatg aagggcatcg cgacaaagac cgcagaaagg
    23521 aaacggtaaa ccgttcatga gaaaaccaaa gataacggtg attggtggag ggactggaat
    23581 tcccgtcatt ctaaaaagtc tgcgggaaaa agatgtggaa atcgcagcta tcgtgacggt
    23641 ggcagatgat ggtggttctt caggtgaact ccgaaaaaat atgcaacagt tgacaccgcc
    23701 aggtgatctt cgtaatgtcc ttgtggccat gtcggatatg cctaagtttt atgagaaggt
    23761 ctttcagtat cggttctctg aggatgccgg agcctttgct ggccatccat tgggaaatct
    23821 catcattgct ggcttgtcag aaatgcaggg ttcaacctat aatgccatgc agttattgag
    23881 caaatttttc catacaacag ggaaaattta tccttccagt gaccatcctt tgacccttca
    23941 tgcagtcttt caggatggga cagaagtggc tggagagagt catattgtag accatcgagg
    24001 cataattgac aatgtctatg tgaccaatgc cctaaacgat gatacgcctc tggccagccg
    24061 tcgagtagtg cagaccatcc ttgaaagtga catgattgtc ctagggccag gttccctctt
    24121 tacctctatt ttgcccaata tcgtgattaa ggaaattggg cgggctcttt tggaaaccaa
    24181 ggcagaaatt gcctatgtct gcaatatcat gacccaacgt ggggagacgg aacactttac
    24241 agatagcgac cacgtggaag tcttgcatcg tcaccttggt cgccctttta tcgacactgt
    24301 cttggtgaat attgaaaaag tgcctcagga atacatgaat tccaaccgtt ttgatgaata
    24361 cttggtgcaa gtggaacacg attttgtagg tctttgtaag caagtttcgc gcgtgatttc
    24421 atctaacttc cttcgtctgg aaaatggcgg tgccttccac gatggagatt tgattgtgga
    24481 cgagttgatg cgcattatac aggtgaaaaa atgagtttca cagtagcagt aaaagaagaa
    24541 atcctgggcc aacaccatct gagctggcat gaattatctg ccattatcaa aatgtctggt
    24601 aacatcggtc tctcgacttc gggcttgact ttgtcagttg tgacagaaaa tgccaaactg
    24661 gcccgtcacc tctatgagtc ctttctccat ttctatgaaa tcaaatctga aattcgtcac
    24721 caccaacgga gcaatcttcg caagaatcgc gtctataccg tttttacaga tgaaaaggtg
    24781 caggatttgt taagtgattt gcacttggca gactctttct ttggcctgga aacaggtatt
    24841 gatgaggcga ttttatcgga tgaggaagca ggtcgtgcct atctctgtgg cgctttcttg
    24901 gcaaatggga gcattcgtga ccctgagtca ggcaagtacc agttggaaat cagttctgtt
    24961 tatctggacc acgcgcaagg aattgcctcc cttctccaac agtttttact ggatgccaag
    25021 gtgcttgagc gcaagaaggg ggctgtgacc tatctccagc gagcagaaga cattatggac
    25081 ttcttgatag taatcggagc catgcaggca cgtgatgatt ttgagcgggt taagattttg
    25141 cgagaaaccc gtaacgacct caatcgggct aataatgccg agacagctaa tatcgctcgg
    25201 acagtttctg ccagcatgaa gaccattaac aatatcagta aaatcaaaga tatcatgggc
    25261 ttagaaaatt tgccagtaga tttgcaggaa gtggcgcaac tgaggattca gcacccagac
    25321 tactctatcc agcagttagc agatagtctc agcacccctc tgaccaaaag tggtgtcaat
    25381 cacagactca gaaaaatcaa taagatagcg gatgaattat aacgatataa agcaacccct
    25441 tgaattatca atatcttcaa ggggttttgt tgtgttatga aatcaaaaag gggcaatcaa
    25501 ggggcagaat taaaaaatag tatctaattt attgaccagt ttatcctcca tatcttcagt
    25561 agtatgagaa tagatttcca aagtcatttt tgcatttgag tgcccaactc gatccattat
    25621 tgattttatt gggaggccag actctgctaa aaacgaaata tgagaatgcc taaaaatatg
    25681 gctagataag tttttttcta ttttggcctg ttttccatat ttttttaata tctgtatgaa
    25741 gcaagctatt gttgtaggtt gattccattt ttcaaaacag aaaatataat catcgcttga
    25801 caatggctgg aaacgttcgc taagtcgtac tatttgtctt tgaatagctt ctatgacact
    25861 ctctgatact ttgattgtcc gtattgaatt tgtagtcttt ggtagcgtct tgattttgtt
    25921 tactgaatca aaattacctg tgatctcaat tttgttgttt tcgaagtcta tattcttcag
    25981 ttgtaaggca gttaactcac catatctcat accagttaat gtcagcacaa gaaccatatc
    26041 agcgtacttt tggtgatatt ctcgacgatt aaggacatcg acaagtgctt ttatttcttg
    26101 catggtgaga aagttgttac gctttttttc cagttcttct aaagtctttg gtttttgagg
    26161 aatcgtagta taatcgacct cgttgttttc aatgtaagag tattgaacag cgtaattaaa
    26221 gatacctctg agcctatgcc gtactttttt agctgtaata tatccgttgc tttcaataat
    26281 tgtttcaata gcctcttgaa gaaaacgcct gtcaagatta gcaagtatgg tatcggacgg
    26341 tatgacttcc ttcatcttct tatcaactga tttacaatta tgttttgttg attcctttac
    26401 tgtttgcgcc catgatttat agaaaaggtt atagatttct tcaaatgtaa tgctttctac
    26461 ttgttttgtg ctaagttttt tatttatctt ctcttgcaac aagatagcag cttgatttct
    26521 tgcctgggga gttttcttct ccatggtcac tgaaactttt tttaatttct cggtatacgg
    26581 gtctttgtat cgttcaaaga atttgtattt tccgttggga agttcttcca tccacattgc
    26641 gtttacctca cttttttgtt aaaatgggta taagaaaaag agctttttaa tgcttttttt
    26701 cttaccacta gcctcacgct ctcggtctgc aaacttctga gcgtggggct tttttgagtt
    26761 gtttccaaaa tggaaacagt tggttttaat ttatactttt ggttcattac ggtgccaatc
    26821 attaggaaaa cctaaagact ggttgattac attgatgtct atagaaggca gctttttctc
    26881 tagtttgata actttttttc taagagtatt ccacaaaatg ttgaatgctg ctttactaat
    26941 aaagcattga aggctaataa ttgttgaata tacagttttt ctactgtcat ctcccatcaa
    27001 gatctctttg ttatgaatcg tttcccaaaa cgtactatta gaacggcatc tgaagtttaa
    27061 taagcgatta ttgtgagcgc atttgtttcg tacctcgtta atatttttta gaaaagatat
    27121 caaggtttct ggtgggaaaa catcgttaaa gtcaggtatg tttgtgctta taaaacttac
    27181 taaatcccgt gcgatttcat tttggagtga attaggcagg ttttcaataa tcgtgcgtaa
    27241 atctccaaac tctagataat cagttagtac ccagattggg acatctgaat gagtatgtgc
    27301 gtagtggtga attgaatttc ctctgtatcg cttgtttgtg tttatgattt tggatagttt
    27361 tgatacaata aatcccacgt ctaatatttt attatctgca taagaattgg tgtttaaata
    27421 agcgtatttt tgactggggt aagcttcggc gaatctgtga gcagtgattg acttgatatg
    27481 gtgttcagct tcaagaatag cttgcaaaat ggctcgtttt acatctttgt caaatgtata
    27541 gagacttgaa acttcgtcaa atgtgacgcc gtcaatataa gtgtcagtac cagggtgttg
    27601 aaaaaactta ctgtatccat tgataatatt gtagtaattg ttacttagca ggtacttagc
    27661 tgctttagat tcatctgtaa tggataaccc tctgattttt agtgttgcga tttgttcctc
    27721 gattgtttta aatggcttca aaaaaactcc cccattctaa tttagaatga aggagtttcc
    27781 ccgtatcggt ccccgtagag atcccgacgc tttttctcta atgaattcat tctaaatgat
    27841 ttttttaaaa aagtcaactg ttttttaata tttttaaaaa ataatttttt tattcccctc
    27901 tatacacccc gactactgca taaatcttga tgtgtgtgtc ttcggctggt gggaagtcta
    27961 ggatgatgtc ttcgtacttg tcattgagtg acactaggcg taagcgtccg ttttcggtat
    28021 agatcttctt aaagtaagaa cggtctccgt atgcgataac tgctaggtct ccgttgtagg
    28081 tagtcagccc tttgtctact aaatagagaa tatctccgtc ttggtagtca ggttgcatgg
    28141 agtctccgct gaccttggta gcaatatcgt ggcgtggtgg ttgctcgtca acctctatag
    28201 tctctctgtc tgtatcgtcg taaccgaatc catagttgaa tccagaagct gctgccgtct
    28261 cagatacaac ctcaactttg tacaagctga tgacttccga tacttcgttt accttcgttt
    28321 cttcttcgtt tttttgactc tccagaagct cttcagacgt tcgtagaacg atttttttat
    28381 tttcagtgtt taattttcga gctgtgtttg taatttcttc taaaagggag tctgacggtt
    28441 gagcagtaga aattttgttt tcgataaggt cagatttatt tatattaaaa tagtttgcca
    28501 aaagttcaat tttaccaatc cgaggataag ttattccttt tagccagtca cgaactgtag
    28561 tgtatttcaa atccaagtct gcacataatg tatttctgtc tactcctttt tgctccatgt
    28621 aaaaacttag attattggca aaaatttctt tgttttcgac tttcatttcc gcccctcctt
    28681 acatagtata ttttacggca aaaacgcaaa aaagtaaaga ataaaataaa aaattgcgaa
    28741 aaaaacgcaa aaaacacttg acattgcggt taaaccgcag tataatataa tcaagcttaa
    28801 gggaaaggag gtaaggcaaa tgatggaaca catcataaaa agcctagcaa ccaaggacac
    28861 tgcaaccgtc atcttggtac taggcttaac cagagaagca cgtttgtggc acaaacaaat
    28921 cttagaacac aaacgtaagc ttcaaaacaa aaagtagaga aaggggcgac gccccaacct
    28981 ctacttgata gtgtaccatc atttgccgtg aaaagcaatg gatgaaaatg ttggtttgat
    29041 aatcctagca ggatttgtga ttgtatcttt tactatccgt aagatagtgg aataccgatg
    29101 tgataaaaaa gggaaggagt aggaagatga ctgaagaaga aatcgaatta ttaaaattct
    29161 taatgacaga ctacggacga gggtatctag ctgggttagc tagtgggctt tcaatacttt
    29221 tgaaaatttt aaaaaaagca gagtaagttc tccactttca acgaattatt ttgatagctt
    29281 atctacagct ttttgaagtt cagcgatccc gttaatagct ttagtaatat ttttgatatc
    29341 aacttcgcct gtaaaaaatt ttgaagcgat gtctacttgt tggctttgtt tcaaggcatc
    29401 cagtttcaat tcatgttctt tttcaagtct ctgtaactca ttttcagatt gtgtttttaa
    29461 ttcttttatt ttggcgtttg tttgatgttt attagtgaga taaacaagaa atgcagggac
    29521 gcaggaagtt aaaaaagtta ttgcaatttg attgaaatcc ataattttct cctttctatt
    29581 ggaattttga ctaagaagaa gtttaagcat ttgttgattg gaaaagggat gacacagaag
    29641 gcattagctg aaaaagctgg tatcagtcca aatacaatca gaaatatcaa aaccgagcgt
    29701 atttctttta agaatatgtg caaaatcgct gatgcactgg aagtcagctt agatgaattt
    29761 agataaggag gtggtaatgt gcaaaaaatg actttaaaaa cactaagaac actcaaaaat
    29821 tggagacaaa gtgatgcagc agaagctgta aatgtttcgg ttgatacatg ggggcattgg
    29881 gaacgtggaa taacagagcc aagtgtttca aaagcgtatc aaatcgctaa tgtttttgaa
    29941 gtatcagtgg atgatattat ttttttgcct gatattgcgg tttaaccgta acaatgtaat
    30001 taaaaccaaa aaaggacctg gttgtaatca ggtactcaac ggaaagattt gaggaggatg
    30061 gatggaagaa tttattgatg ctcttgaaaa agaaaaagac caccttgaaa aagtcattaa
    30121 ggtagtcagc gctggtggta aatttctgag attgccatat caaaaaaagt cacgctcgat
    30181 tagtgagtat ctgaaattga tttctcaaaa tcttgataga ctgagctgtt tatataacca
    30241 aagaggagaa agaatgacag acagagaact gtttgagtta ccagaagatt acgtagaatc
    30301 tactggactt gacaagatca catttgaagt accttttgaa ttgtttacga aaattctaaa
    30361 agggtatgga cataagttgg cgtgggaaga ttaccgacaa ataaaaatcc acccaagcac
    30421 tagaacaaaa aagacggttg gacagtgtca gtttttgttt agtatttgga tgaatgacca
    30481 tttaaaacca gcgattaagc cttcaaaaga gttgcagaaa gaacctgtgc gtaagacaaa
    30541 gagactgaaa cgtcttcgta agttagcaca aaatcttctt catcgcatga agggttgaga
    30601 tcgccgatgt atgcaccttg ctctgttttg cagattagaa gagtgccatc ttcatttgta
    30661 actgcattta gatagggtgc caaatcagac ttagtcataa gttatcctcc tttctgctta
    30721 tattatagca gaaatagagg ttagaaatag aaaggagtag gaagatgaga ccaaaacgat
    30781 atccgtatag tgggaaaaaa gagtccacct ttgtaaaggc agaccctgag ttagttgaaa
    30841 aacttttaag aaacactagt tttcttgagt gtttacaaaa aaagcctatc aattttcaga
    30901 tagactcaga agaatttaag cgtcttagct atgaagccat tcatgatact tctcaagtaa
    30961 ctcaatagta gttattacag aagtcaaacc actgaccttc cccaattgca attcgtctgt
    31021 atggtcaatc tgtttagtag cttcattagc tttagcagag atagcttgca tatcttcagc
    31081 tgttaaagat tctcgaaaat ctttaaagga tttcataaaa actcctcctt tctattggaa
    31141 ttttgactaa aacggtgaga ggtcctagtc gagattatta tagcaattta ggaggatatt
    31201 acatcggtct tgaggctgat ttttggaggc aatattggaa gataaaatca tagaacttgc
    31261 tgattacttc atcagcgaat ctacaacgta cagagaagca aaaatagcgt gtgagaagct
    31321 attgaaacaa gtcagccatg agattgaact cagggcgatg gaaagtagga cagtatgaaa
    31381 gaagcagtaa aggaatttct aaaattcagg agccgattta caaaaataga atggtttgaa
    31441 atcaaccaag ctgtcgaagc tcgtttaaat caaaaagccg accagttgaa actggacgac
    31501 gtagatttag aaatcatttc tagcagacta gaaaaagtta tctagaaacg atttgaatga
    31561 acattggatg gatacgatag tcagcgccac gatagtgaat gtagatataa tcctgatggt
    31621 acatcgagtt tgcttcaggt ttagaaattg gtgagtagag ttctgcattt tcttcccacc
    31681 aaatgtaagg actagccata tttggtccca ttacacaatc gtcgtcggct gataggttca
    31741 cccaatttcc gcaaagacat gcgtgaattt cagtcataat attacctcct ttctggtttc
    31801 attatagcag aaaaggagat agcaaaaaag cacctgacgg aaatcaggcg catacttaaa
    31861 tattcaacat gattataaca cgaaaggagc aaaaatggaa gcagttgaaa ttgtaagaat
    31921 taaagatgtg attattgaaa aagtctctgc taatgatgaa gagttaaaac gtatctttgg
    31981 atgttcaaaa cgacaagcag gagagcgaag aagagaaatg caaaaactcc ctagtcagca
    32041 aaaacatctt ttggatagtg gacaacttgt aacgattaaa ggtttctatg aatacttgca
    32101 atatcgtgga actaaagctt ggaaaaaaga aatggaaaca agcaagaaaa tgaggtcagc
    32161 aggatgaacc tactatcaag aatcaaaaac tatttttcgg aagaggtcaa agaaactaat
    32221 ctcgactgga aagaggtcgc tttagacctc aatcaatcac taattgaaac acaggaaaaa
    32281 cttcaagaag cgaatcaaga aatcgcagac ttgaagaaaa tcgtagcaat ctataaagaa
    32341 aaggagaaag aaaaacgatg gaatatattt acctggtaac aatcgtagga attggactat
    32401 ggtcgctagt aaataaacta gatgaccacg ctgaaatgaa acaaaaagag cgccagctga
    32461 tggcaaacaa tgtcgcacgg atgaatctga gaaattcaga taagcaattt acttatgatg
    32521 tagaaccgcc tgaagggttg aaataaggag gagaaacatg actcaagctg aacgaattag
    32581 ggaatattat agagagcacc ctgctgcctc atatgatgaa gtggctgagg tcgttggtac
    32641 aacaaatagt aatgtgagag cgaacctggc caaagacatc aaggcaggca gatgcgttcg
    32701 cttggaagat aagtcatacg attactcgcc ttactataac catacacagg cactcactga
    32761 gttggttgac tggaagaatg acaacagacg tgagtgggtg gatatgctga caagagcagc
    32821 agagaaagaa acggatagca acgttatgcg tttgttaatc aaagaagcaa ataaattgat
    32881 gaaagaggtg actaagtaga tggtacgaaa taaaataggt gatttaacta acacgctctt
    32941 cgctcaatta gagactctgg atgataggga tcttacagca gatgaattaa aagtagaatt
    33001 acagcgctcg aaacaaatgg tcgcaatctc aggtcaaatc ttacaagcag gtcaattggc
    33061 gctagatgct gaaaaattca aagacaaggt aggtgaagtc aatgccccga tcgctttgct
    33121 ggaaggatga gtacacggag tacatgcatg aaatatgccc tggtcgttta actcctgaag
    33181 taaccaggtt gctgaatgaa aaatttggta cgaattataa caagagtcaa atcggtggcg
    33241 tacgcaaacg tctagggtta gcagttggaa aagtctatca aggtcgattg ctgacaaagg
    33301 agcaacatga ttatcttgta ttgatccaaa aaaataagat ttctcgtaat gtcgcaaatg
    33361 aaatgaacca aaaatttggc ttatcgctaa ctgagaaaca gattaagagt tatcggagaa
    33421 ataataatct acatagtggt ttgacaggaa gattcgagaa aggtcagact cctcacaata
    33481 aggggaagaa gtaccccaat atgccaaaaa acagcgggca gttcaaaaaa ggtaatcgac
    33541 ctccgaatta tgtacctgta ggaactatca actatacaac agacggctat ccgaaagaaa
    33601 aaatcggaga acctaatcaa tgggttttga aacatcgtaa agtgtgggaa gaacatcacg
    33661 ggccgatacc aaaagggtac tcaatcgttt ttctggacgg cgataaaaca aactatgata
    33721 tttcaaacct ggcatgttta tctaaaaatg aaatcgttag aatgaatcaa aatcatctat
    33781 tcacgtccaa cgctgatttg accaaatctg gtattggact aacaaaactc acaaacaaaa
    33841 tcagagaggt agaaaaaaat ggctagttta tacgaactaa caggtcagtt cctgacaatt
    33901 tatcaaatgg atattgacga cgaaacaaaa gcagacacgc ttgaggctat cgattggcaa
    33961 gaacaatttg aacagaaagc agaaggatat gcccatgtta tcaagaatct agaagccgac
    34021 gtggcaatgt acaaggctga ggaagagagc ttcaaagcca agaaacaggt ggcacagaaa
    34081 aagctggatt atgtcaagga taacattatg gcagctatga atgtcacggg gcaaaccgaa
    34141 gttaagagtg gtgccctgat tataaaaatt gctaagaatc cagaatcagt caaggtcaac
    34201 gaagacgacc ttccgaaaaa atattttaca aaaaaagtga cgcttgcgcc ggacaaaaaa
    34261 acactcaaag agttgcttaa atctggcaag aaagtcaaag gtgcggagct tgtccggaca
    34321 gaaaagttgg tgattaagta atggaattga tgaataaaac acgagtaaca gattcactag
    34381 cagttgtgat tggaccagaa tcgattgaag tacttgttac tgaaggtttt ctatttgatg
    34441 ttgcgattcg ttttgtaaaa gtagacgaaa caaatcttga tcaaggaaat gaaaagccag
    34501 tattcactcc ggaatacaag ctggtcacag ttgctaaata caaggaaaaa cctatctttg
    34561 aatcggagga agatattcga aaatttgaga agcaagcaaa agaagttaaa tcgctatttg
    34621 cctttgcaaa ggtaaataaa caaaattggt ttaacactgc cctttatcca ggagtgctga
    34681 ctgagaaagt tggtgtttga tgaaaatttt agctattgat ccaagcagta ataaaattga
    34741 aaccagcaca acaggagttg tcttgttgga taatgcaaga ttagttgata gctgggttgt
    34801 ctcttatggt atgagaggtt tcgctgattg gtttcacgaa atcggaacaa atcttgaatt
    34861 cgatgtagtt attgttgaag aatttaaggc gagggataac gacaagtcga aagataatag
    34921 cgtggcagaa accatcgcct atatccaact ttgctatcca ggtgccattc ttcaattcaa
    34981 tgcaggttac aagtcggata ttccaaacga tcttttgaaa atcttagacc tttggaaatt
    35041 tgaaaaaagt catcatcaag atattcgagc agcagcaaga cttggattat tttgggcaat
    35101 gagaaatgat attgaagaag tggttcatga tatcggaaag gtggtgagtg agtatcacaa
    35161 taacgctaag aaagtggcaa gctgaagcga ttaaaagaag tgaacattta tctaatggaa
    35221 tctttttaga ggctcttggg ggcagaggca aaactatctg tgcacttgct attgcaaaac
    35281 ataaaaaagc taaaaaaatc atcatcacaa acaatcgact agctattctg aatggttgga
    35341 tagatgcagt caagtttatg aattttgata aaggtgttga gattatcatt cagacagata
    35401 gatatcttca aaatcaagtc aaaaaggggc ataaattaga ttgtgatgtg ctgatagtag
    35461 acgaatggca gaatatgtct tctgacaaac aagtggcctt atatcgcaaa ataaagcgaa
    35521 aatacacgat aggtctttca gcgacaccaa ttcggaaaaa aggacaaaat ttctatccgc
    35581 ttgaaaaaac ggtatttggt tgggcaaccc caaataataa atttgactgg caaaagactc
    35641 atgggaaaat ggtctatgat ccattcagct actcaaaaga gaagtgggaa gatttcagga
    35701 attatgaaag ttatatctca aacttgccga actttttccg ctgggaagac attgaaaaga
    35761 ttgagaatgc cactgaaaat aacggttttg aaaccaagtt ctacccagtc acagttaaag
    35821 ctggaaaccc tgagaaatta gctgagttta ggcagcttaa cttggtcact gttggagaca
    35881 agacggctat ggccaaacag tcctttggtc gcaagacctt tgaacggtac ctaaatcaaa
    35941 ctggtgtgat cgttgatttt ccaaagttga aaccagttaa cgctgatacc cctctcatgc
    36001 tcaaattgga cggattgatt gaaagagcac cacacgatat gttgattgtc agtaaatcta
    36061 agcagattgt caacgtcatt agcgagcgcc atcctgaaat tggaatctgg acgggcgata
    36121 ttcaagaagg actttataag aaattcgtgg ttgctactag tcaagtgtta ggtgtcggag
    36181 tagacggctt gcaacacaaa taccaaacta ttgtcgtatt ggatccagta gaagaaggtt
    36241 ctggagaata tgatgattat cgacaattgc tctggcgcat aacaggaagt cgtcagcagc
    36301 atgatgtaaa tgtaattgaa ttttattata aagaaagtta aaaaaaagag gaaaacaaaa
    36361 tgaataaaac aactgaaatg atcgtatttc gtagccgtaa aactggagaa tttcttaatt
    36421 cttacaagga cagaagttct ttagcatttg cagctgactt ttgcagcttg gaatattgtt
    36481 tgaagcttcc tcgtaaaaaa tacgaagaca acaaaaagac ttacaaggct cttgctgcag
    36541 cttttgactg tgaaattgtc gcagttgaag cggaatacaa attgacctat ccgaatggat
    36601 cagaagttga acctatcaag cgtgaccgtt catcaattga ggacatgatt aaggatatta
    36661 ttggaggggt tctctaatgg catttacact tccagcaaat aaaccacaag ttcctaaaga
    36721 taccccacga aattttttca tctacggtga aaccatgagc ggaaagtctt atcttgcaaa
    36781 tgaattccca aatccaatcg ttttgaacac agacgggaat gcagaagcta acactgttcc
    36841 aagcattcag ctgatcaatg aaaaagatga caagggacga attaccaatt cagtaattaa
    36901 gcagcttgga gatatcttgc ttgctctcca gacacagaag cactcttatg aaacagtcgt
    36961 tattgatgta attgacgatg ttattgaaat gattaagatt gcagtttgtg atgaattaac
    37021 cccagttggt aaacctcgct tgaaatcctt gtcggaaatt ccatacggca aaggatacga
    37081 cttctttaac caagctatca cagaattagt cattgacctc aaagcattgc caatgaatgt
    37141 tatttacatc agccgtcagg tatctgaata tgatgacaat ggcaatgcca ccaaagacaa
    37201 gccaagcttg aaagataagt atgtcaatct tatcaatgga aactctgatt tgatgatcca
    37261 cactgaaaaa ctcggcaaca actacaaccg tgaggttgac cgcaagcgta agacctatta
    37321 tgcggaccag gttgatgaca aggccatatt gaaaatcttg gcaactatcc gtggggctgt
    37381 tgagcctgca aagggcaagc tagcccctaa aaaagaagca gctaagacaa ctaaaccagc
    37441 taagaccgaa aaaacaaaag aggcacctaa gaaagaagtt gactctgatg atgaactatt
    37501 ttaagaaata aaggagaata cacatgagct tactagatat cgcaaaatca atcaaaaaag
    37561 agggctttga cccacgcaaa gacagcgcca acggtcctgc accaatccca gctggtactt
    37621 atccagtagt cctgaagaaa gcaaccttca acgtatcgga caaaggctgg gaaagccttg
    37681 gttatcaatt tgaaatccgt ggcggtgatt acagtggacg ctctgaattt gcaacatttg
    37741 gcacactgac tgaatggaac ggtaagaacc ttgactgggc agttgaacgc actatgaaat
    37801 tctttatcaa agccttggtc cttgctggcg acagtatgca aggaaatgaa gaagacggta
    37861 aagccttgga agaggctcta aaacgtaagg cagttggctc ttactacaac cttgttatct
    37921 ctgtgactaa ggggaaagat ggccgtgagt tccgaaacta tgaccttgaa gaagaagcac
    37981 aaccgctgac tgaagctgat attgatgacg atgacctccc tttttaagaa ataacaagtt
    38041 ctgggtcatt gatgaaactg atgaggaatt tggtcctttc acgacagtag aagaggctta
    38101 tacagctatg ctaacatact tggatatgac tgaagatgaa tatcaatcaa attatatggc
    38161 ccaagaactt gtttatattt acaaagagga gaagtaatca tgccgtcgat gaaagaatac
    38221 gcattacagt atcaaaagtt agggttctca gtcattccaa tcaatcctaa aaacaagatg
    38281 cctttgatta attttgctga taagccagcc atgactccat ctgagattga aaacttttgg
    38341 gacggctacc ctaatgcaaa cattgcccta aagactacca acttctttgt cattgatatt
    38401 gacaaacacg gcaaatcgaa cggttttgaa tcgctaaaaa aatggaaaca tctaaattta
    38461 atcgaaccga cactgcaagc taagacggct agtggcggta aacatctatt ctacttcaaa
    38521 cgagaagatg agccgatcac tcagatgatt ggattcttgc ctggtgttga tattaaggct
    38581 cacgaaaata attatgtgtt agtcgcaccc tctgccacag ataaagggca gtatgagtgg
    38641 gatctggaaa agtctaagga aggtggcacg atggtcactc cttcaaaata tttaatccag
    38701 tctataaaaa aacagtatgg cgaaactcac ggttataagt atgatggtaa ggacggtctt
    38761 agggatttag ttagacgttc acatactaga gaccgaacac agactacaga tctctttgaa
    38821 accatcgccc ttggttttgg tgatgaaggt ggacgaaatg acaaactagc aaaattcgta
    38881 ggtggtctct tatatcgtgc ggtcgacgat ggtgtagttg ttcaacttgc aagattagca
    38941 aatgcaaata gtccaacccc tttgcctgaa aaggaaatga tgcgtactat tgaaagtatg
    39001 attaaaaaag ataggaggtg attgtgattg gtaatgtagt aagtattgac tcacaaccta
    39061 agatgataac gactgccaag ggagacatca aggccaacag tccaagtaat gtgttgatgt
    39121 ctttcaaagc tgatgatcag ttgagtattt acctaaagca caacgatttt tcccaagagc
    39181 atgaactcct taaagatatc aagatcggca acactctttt taaaaaaggt gagctccctt
    39241 ctaactttga ttcagtcgta aaagtttact ttgaaagtgt attaggtgtt gctttttcta
    39301 accaggcgat gctggacggc atggaaactt ttttctcaga acgttcttac aatccagtca
    39361 ttgagtatat ggaaaaggct gctgaaaaat gggatggtcg taaacgaatt gaccgaatgc
    39421 ttcaggttta cctgggggct gaagatatcc ctttaatttc taaaatcgct caaatgtggc
    39481 tagttggtgc agttgctaaa gtttatgatc catacgttaa gtttgactat gttctggatc
    39541 tagtcggtgg acaaggagtt gggaaaacat ccctccttca aaaattgggt ggcgaatggt
    39601 atacggatgc cgtaacagat ttctctaata aagataatta cgacattatg ttaaagagtc
    39661 taatcgtcaa cgatgatgaa atggtggcca gtaataggat gagctttgct gaaacgaaag
    39721 cctttatatc aaaaactagc ttacggtatc gtaagcccta catgaaacgc acagaagagt
    39781 ttgccaaaaa cttcattata gccagaacta ctaaccaaac agaatacctg aaggacaaaa
    39841 ccggagaacg tcgatttctc ccgattatgg cagatagcag gcagcaaaag aaacatccaa
    39901 tggaaatcga gccagagaca attgaacaaa tctggggcga agccgtcgca atttatcgtg
    39961 ctggtgctga tttgatgttt gatgaagata ctgaagacga attgaacatc tatcgagaac
    40021 agttcatgta tcgtgatgaa gttgaattac aagtgcttga atatcttgat atgcccgtcc
    40081 ctgaaaattg gcaaaactgg tctattcagc aacaacatca atacacaagt aaatatttcg
    40141 ataatagtag cgattttgat cctggaagca aaaaactaga taaggtctca actcgtgaaa
    40201 tgatgtacaa cttatttatg agaaattcga atgacaggaa gctgtcaacg aagattaaca
    40261 tgatcatgga taatcatcct gattggaaaa aaagtgtttt ccgggcagga ggtaaaagta
    40321 caaaagggtt cgtaagagtg aaagattcgg aaaaaactaa tcggtagcaa ttaaaaattt
    40381 atcggtagtc atcggtagca gttgaggggg agatcggtag cattctaccg ataaaatagg
    40441 acatcggtag cacatcggta gcagtctaac cccttgatat tactgacttt tatttaatat
    40501 ttatatataa tgctactctt ctacctatat ttttaaaaaa agtatataaa ataatagtaa
    40561 taataaaaaa agcctataaa atagggattc ttgaaaaaaa ctttttactt tttagaattt
    40621 atcggtagca cggtagcagt ttagaaaaaa agaggtaaaa atgtcataca cagtaacact
    40681 atattttgac aacatggtag atgaaaccca cttttttaag aaagaaggtg atgctgccaa
    40741 atgcaaggct cagatcgaga gcaagtatcg aggtgatcga atgtataaag taaagatgga
    40801 ggagatggag taatgagtta tgatttggaa atcttagcga aaatagagag tggagattat
    40861 atttgtattg ctgaacctag atatagttct ccgacctaca atcttggaaa aatgtttagg
    40921 gtggctatgg attgggattt cgaccaaggc acaatttaca atgttgctga tatttttgaa
    40981 aatattaaac gtggcataac tgaattggaa aggcaacctg aaaaatatgt acaatatgaa
    41041 cctgcaaata aatggggaac gatcaatgat gcgttatatg ttttgagatc gttaagggac
    41101 tgtattttag aacaagatat tgatacgaaa tatttatatg tgaggtggta aattgaaacg
    41161 accaaacaga tacccgtaca ctaaaaatca atgggttgaa gaaaccgttg atcactatac
    41221 ttataaaaac gatatttgct atacaagtca cattttagaa aatagactta ctggagaaat
    41281 taaggacaag gagttgaagt gatggaagag ttaaagaaaa aagttaatgc agtatacaac
    41341 tggacggtag aagacgggaa gccgcaacct cccaagcaag atttaccaca agcggtgaaa
    41401 gaccgggcgg actatttttg ggaaatggca gaagatggta tgacgtttat gggagcgatg
    41461 gaatgtatct tcgctgatga aaagcctaca gactatgatt tgggagctac taagggttgg
    41521 ttgccaaaat ctaaggagtt tgatgattgg gttggctatt cgccaagcat ggctcgggta
    41581 attattgcag tttatttgat ttatagagga aactaagatg aatgtacagc gattaattga
    41641 gaagtataaa aaacttgagg gtgtatggga tgctgaagga gcagagctag ctcgtcaaat
    41701 ttttctagaa gacttgaaac aactagacga acaaaaacca gtcaaagttc cgcagtgtgt
    41761 ggcggaatat atagaattta aaaagaaaaa caattttcat gtttacggtg caatgagagt
    41821 aattgaagat cattatgata agaaagttcc tgattggttt tacgaaaata acatcgaaaa
    41881 attctgtctt gcttggctta acggctacga gatcgaaaaa gagaagcggt attttgttaa
    41941 gattaaaggg aatattaaag aaaatatgtt ggtttatgga gaacttttga aaaggtattt
    42001 ctttacaaaa agatttagtt tagacgatgt tatatattcc cacacccgta aagaactaga
    42061 agacgcaaac ttcggctggg tgtttgattg tccagggatt gagattgagg aggtggagtg
    42121 atggaagatg aggaaatcat aggcaacatc tacgaaaacc cagagctttt ggaggtcaac
    42181 gagtgagata ttttaaaatc ctatgtattg ttttattcgc atccttactc gtagcatgtc
    42241 accagatttc gagtgggaca gtggtagata agtacattga tgaacctcac acaacgttca
    42301 tacctgttat aaatggtaaa agttcggtac ttgtgccaac cagaaccaaa agaaaataca
    42361 ttctggtcgt ttcaggattt acaggtaata agcaagttga agaaaggttt gaagtgacag
    42421 caaatgaata caagcactat gaaattggca atacttttat acaggatgcc gttttagaaa
    42481 ataaggagga taaataatga gacctaaaaa atacccacaa gatactcaat agctactaaa
    42541 acaaaaaaag ccaagacacc ctctgtctca gctaatagtt ctcacaaaga ctattatatc
    42601 acaaaggaga cagagagtga acaaggctaa agaactattg aaagagttgc agaatctgga
    42661 catggacatt caaagccgta tagatgaaat taacgagctt gaggcaggtt tgctctcaag
    42721 tcctaagtgg tcagatgtca aagttcaagg tggtcaagct agaaaagttg atgatgtcta
    42781 tactcagctt gtcgtgatga aagaggctat agaacaggat actaaagagg ttatcaacag
    42841 aaagctccaa ctaggtagga tgatcaatag gcttaaaaat ccaaaacata gaactatttt
    42901 gagaatgact tacatcaata agatgtacgt tgatgacatc tgtgacagca tgaggggcat
    42961 aagttctcct acttactatc gtttgaagaa acaggcagta aaggagcttg atattattct
    43021 ttcagaattg atagtaaatg atagtaactg tacaggcatg aagtctaaaa tctgttaaaa
    43081 tggtagtatc aagaattgaa aagagaggtc tcagaattgg tagatggtta cctgtaatgt
    43141 cagggggttg taatggcctt ggaggttcaa atcctcccct ctcctttgag tgtttgtgtc
    43201 ctagaatggg gtaggcagta ggcttagcat tcatatatca ctcattaact taaaaatggt
    43261 tgcggaagcg actggacctc gcatgattgc gtagctaatt atattccgga taagttataa
    43321 gctagagggt ttgattccct cagaggtttt aaagactaca aaaaataaaa aagaagtcaa
    43381 aatttaatac gcacgcaagg ttgtagtcgc cttgcaagaa ggtcgcacat cgtgtggctt
    43441 tttttgatta ttcgaagggt ggtgatggaa aattgagtgg attgagaata aaacaaaaga
    43501 gatttgcaga tgagtacatc atctcaggta atgcgacgga agcctataag aaagcaggtt
    43561 atcgtgtttc tagtgataga gtggcaggcg ttgaaggaca taagttacta aagaatccta
    43621 agattaaaag ttatatagat gaacggttga aacagcttga ttctgaaaaa atcgcagacc
    43681 agcaagaagt ccttagttat ctaacctcgg taatgcgagg agagacgcaa gaacagactt
    43741 tgataagcat cggagaattg ggtcaaacga ttacggatat tgatgttgga gcaaaagaca
    43801 gaatcaaggc agccgaacta ttaggaaaac gtcataggct ttggacagac aaagtagagg
    43861 cagacgtttc tggaacggtg gtgtttgcaa atgagtcaga cataccagat taaacaaagt
    43921 gatattgtaa tcgacctacc taagacagta ggagctgggt acggacagtt ctggcgctca
    43981 agaaatcttt atcgtgttgt aaaaggttcc cgtggttcga agaagtccaa gacaaccgct
    44041 ttgaattatg ttatccgtct tttgaagtat ccctggggca acttgcttgt tattcgtaga
    44101 tactcgaata ccaacaagca atcaacttat acggatttta aatgggcgtg taatgtgttg
    44161 ggtgtgactc atttgtttaa atttaacgag tctttgcctg aaataaccat aaaagcgact
    44221 ggtcaaaaaa tcctattccg tggtttggat gatgaactca aaatcacatc tatcacggtc
    44281 gatgtcggca gtctttgttg ggcatggttc gaggaagcat atcaaattga gactgaagac
    44341 aagttcagca cggttgttga gtctatccgt ggtagcttag atgtacctga tttctttaaa
    44401 caaatcacag tcacatttaa cccgtggaat gagaggcatt ggctcaagcg tgtattcttc
    44461 gatgaagaga cgagacgggc tgacacattc gctactacaa ccacttacaa atgcaatgag
    44521 tggcttgatg aagtcgatat caaacgctat gaggatttgt atcatacgaa ccccagacgt
    44581 gctagaatcg tttgtgatgg cgaatgggga gttgctgaag gtttaatcta cgaaaacgtg
    44641 actgtcaagg atttcaataa agatgaatta ctacaagatt cagctaataa attatgtatc
    44701 ggtcttgact ttggttttac tcatgatcca actgctttgt gttgttcgtt gataaatgac
    44761 acgacgaaag agatttatgt ctttgatgag gcgtataaag tcggattgat aaccaaagaa
    44821 gttgcgaaga tgataaagga caaaggttat catcgctcac aaatcattgc tgatagcgct
    44881 gaattacgac tgattgaaga gctcaggtca gaacatggca tatctagaat aaaagagagt
    44941 cggaaaggta aggatagtat tatggcaggt gtatccaaat tgcaaggata cgctatttat
    45001 gtgcatccag attgtaaaaa catcatggat gaattttata gttactgcta ccagcgagat
    45061 aaagaaggca actggttgaa taaaccagag gataaaaaca accacttgat ggacgctttg
    45121 cgttacagcc ttcaatgtat cgaaggtgga aaagcaaccg tccgcagacg ttctgattat
    45181 ggtctataga gaggaaagac atgtaccaat atttaaccta tccacgggat ggatatgatg
    45241 agggttcttt gaagaaagac ctgatttaca aattgataac gatacatagc actgaaggct
    45301 cacatttgaa gaagcttaaa agctactatt tgggtgagca tgctatctta gaacacacga
    45361 gacgcaacgt gaacgcacc
//
LOCUS       DAVDHC010000016        44066 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVDHC010000016 DAVDHC010000000
VERSION     DAVDHC010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44066
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.016"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..170
                     /locus_tag="VUR43_001211"
     CDS             <1..170
                     /locus_tag="VUR43_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5412902.1"
                     /translation="LVECLRPVHQVDLQIIAPAFKKYFQQNQIHLHKLFYYAQLFKVT
                     DKLQSYTEVLS"
     gene            170..979
                     /locus_tag="VUR43_001212"
     CDS             170..979
                     /locus_tag="VUR43_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET5412903.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIDIFEEILCSKTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AKKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISLFKVSWT"
     gene            958..1728
                     /locus_tag="VUR43_001213"
                     /pseudo
     CDS             958..1728
                     /locus_tag="VUR43_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            1749..1991
                     /locus_tag="VUR43_001214"
     CDS             1749..1991
                     /locus_tag="VUR43_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412904.1"
                     /translation="MITHFKGLVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            2008..2862
                     /locus_tag="VUR43_001215"
     CDS             2008..2862
                     /locus_tag="VUR43_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET5412905.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTISGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            2916..3275
                     /locus_tag="VUR43_001216"
     CDS             2916..3275
                     /locus_tag="VUR43_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET5412906.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            3226..5583
                     /locus_tag="VUR43_001217"
     CDS             3226..5583
                     /locus_tag="VUR43_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET5412907.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEVVKGKKEEVLPSTANTLYYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDSYRKELNRMMNQNLDSGENNFSAVKLITFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGENRVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGVFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSEENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            5595..8408
                     /locus_tag="VUR43_001218"
     CDS             5595..8408
                     /locus_tag="VUR43_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET5412908.1"
                     /translation="MKDKREIIRARKAFRRSLKDEKKFLKQGKKEVRKQKKDSAVLDE
                     NAWKKEIKEKLEEMREASKAKVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFKEAKVEAKSERKESRKERKTNQKFLYGQESKAKSNFFFHGKNLEELKAKKE
                     VKVAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKENPSSFKNR
                     FRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPATWIVGGLVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     YLFSSETYKDYLSTLWHDLNDGDDLKSMQDLYETPKYKLSKDDQEEIKELKEEGVYAS
                     MQELDNPFEGQSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQTIVAPMDGVVSL
                     DGDNIILTNGKGENESRLTLHSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILENWSVESSINPKRAEGDYLFPPVGATDSSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHAKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFGNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSIPRAGAIVSFVGGTHGTPADYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(8443..9051)
                     /locus_tag="VUR43_001219"
                     /pseudo
     CDS             complement(8443..9051)
                     /locus_tag="VUR43_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263904.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9053..9217)
                     /locus_tag="VUR43_001220"
     CDS             complement(9053..9217)
                     /locus_tag="VUR43_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412909.1"
                     /translation="MATISLTRDIKLTNEDALKILNHKPSKKLQAVLKSIESQNATAP
                     TKNKLISKYL"
     gene            9680..10090
                     /locus_tag="VUR43_001221"
     CDS             9680..10090
                     /locus_tag="VUR43_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HET5412910.1"
                     /translation="METIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GSNPLEKDFQDIDQTSITEPSSVFMEMKQKISDMMESHHKEFIQVLISIETGIENEQD
                     LEDLYTYYMRTDAVSLLSSDLETSPQEVEMEIEL"
     gene            10138..16361
                     /locus_tag="VUR43_001222"
                     /pseudo
     CDS             10138..16361
                     /locus_tag="VUR43_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            16436..16720
                     /locus_tag="VUR43_001223"
     CDS             16436..16720
                     /locus_tag="VUR43_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412911.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYNAYKELKEHYEEVTGDYSFSK
                     RELTSQLEISLQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            16713..17033
                     /locus_tag="VUR43_001224"
     CDS             16713..17033
                     /locus_tag="VUR43_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412912.1"
                     /translation="MTRKEKVMNDLLLIPVIFLAVGGILILLWRLFLIASGLFLIGFV
                     SFLIFIEVYGIYLFFTEPTLYIEDLSQNGLISFTGFYVVFNLALLVCGVLKIISWTRR
                     LKSS"
     gene            17188..17370
                     /locus_tag="VUR43_001225"
     CDS             17188..17370
                     /locus_tag="VUR43_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic salivaricin M precursor"
                     /protein_id="HET5412913.1"
                     /translation="MSKNTSRPEIDSLSFEVENQELSGKSGSGWFTAVQLTLAGRCGR
                     WFTGSFECTTNNVKCG"
     gene            17528..17710
                     /locus_tag="VUR43_001226"
     CDS             17528..17710
                     /locus_tag="VUR43_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic salivaricin M precursor"
                     /protein_id="HET5412914.1"
                     /translation="MRKNNNHKEIDTLDFEVKNQELSGKSGSGWFTAVQLTLAGRCGR
                     WFTGSYECTSNNVKCG"
     gene            17873..18055
                     /locus_tag="VUR43_001227"
     CDS             17873..18055
                     /locus_tag="VUR43_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic salivaricin M precursor"
                     /protein_id="HET5412915.1"
                     /translation="MKSKKVNTEIDTLEFEIDNQELNGTSGSGWWYTAFKMTLAGRCG
                     LCFTCSYECTTNNVRC"
     gene            18142..18318
                     /locus_tag="VUR43_001228"
     CDS             18142..18318
                     /locus_tag="VUR43_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic salivaricin M precursor"
                     /protein_id="HET5412916.1"
                     /translation="MKQDNFEIDSLDYEINSQELNGKSAAGWRTAVRLTVQGRCGWWF
                     TYSYECTSPNVRCG"
     gene            18589..19323
                     /locus_tag="VUR43_001229"
     CDS             18589..19323
                     /locus_tag="VUR43_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002891877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412917.1"
                     /translation="MKQLIVTGLTKIFGQGDNIVHALLDVNLSVEKGEFLAIMGASGS
                     GKTTLLNCISTIDKPTSGEIRFEDFDIIHAKENELADYRAKNISYIFQAYNLVETLTV
                     YENIVLPLQIQGKNIKKHQDKIEEILDKLAIQNLKDKFPNQLSGGQRQRVATARALID
                     DSKLIIADEPTGALDSANSEKLMALLQEINKSFGITILLVTHDPAAAKYSSRMVLLSD
                     GKIMDDLERNSLSNEQYLQEIYSRAR"
     gene            19336..21351
                     /locus_tag="VUR43_001230"
     CDS             19336..21351
                     /locus_tag="VUR43_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5412918.1"
                     /translation="MYPKLILRNVFRNLQTYTIYFFSLTLIYSLLYAFNALPSHPVMQ
                     SLSGAKEMLTTVMSQYMGLLSYLILSAIAFLVVYSTNFVLGRRKKELGLYATLGMKKK
                     QIIRTLFFETMLVNIFSLILGFLLGVILLVILAKIASEFFMANYFGSLLFFDSKSVIL
                     LVYSYLVTSFIVGVMDILTFRKQNIIALIQENGVKKSVLAKGKPALQALLFILSTAVI
                     GFGALYFSDYHHLSLLKSWGILLVSVFVIFVILFYNTLSHFILVSLRKLPQTYYNKLN
                     SFKIRQFSKQADSNSVTLAVLSLTLTLALSLLVFSGSAYTTMNRELNKYSPYDVSVNL
                     YRGQEFQFSQESVKDRLKADGFDFNLIKEEYSYPIYSSDLTYKDLIDTSNLWAHDKEL
                     PESKVPILGISAYNHLRKLQGKKAVDLADNQFLVNANYKGTAKQIQDFLLTTKTLMIN
                     GYSLNLASSKPLETVYFLSSVGTNDTGTLIVPDTVVVGLMEDHTTYVANFKENIDKRK
                     VETFLSQWIEKYYFTRDGAELNPFTYQTKGRIFEIYLGFMGVIVFVMIFVSVIFIIIS
                     LSILSLQTSTSSLDSVNDYQILYLLGNKRKQNRSILLQQILSYFLVPLVIAGPLALAL
                     STALLGYFENFANTSISIDITYLGVAVLLFVLYLLVTYRVSWQIIEN"
     gene            21432..23006
                     /locus_tag="VUR43_001231"
     CDS             21432..23006
                     /locus_tag="VUR43_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5412919.1"
                     /translation="MKQFVKLISKNSLLLWWLTIFNHLTLMIYIYYRIPLDFSTDFSL
                     QMVLLLIIALIAFSYICNIVTFRYSELKLWLLLMMFLISWQSIFNQGVTSTLLHFFDI
                     LHPLNYFLLVYSSLSILFLGEKIGEELLSVSFVLTLITVSSYLLSPSIFLFLSLFASF
                     FLNLVPLILFILYHEELKSKLKYQRRNLWILALILPLSYFFLYINTTGSGVMNLVWYL
                     EILGILAFLHFKTIVSSLQKKVSELKLSYIKAFSRLFLLVMFLLVGIFIIFRLDLNTS
                     FLVLNIMLLLFGICSEELIRLFRSAEMLDSRDYVKVLFLKRNRMVKNLLANEDTEQQF
                     SEFLHNEILQNVMAIKNFNKYSSNQAFGEQINLVTEELVQRIRERMDYYQPMIETDEQ
                     LDIQYQGLINRIVKRYHAENEVVTQFPVHFRLLSPYDKIAYRLVEELTTNAVKYASGG
                     TISLKIDVHDDAIFIISENDCLQIEKSLGYGLKNMSNKISVLGGQMQIFENNKRFRVE
                     ITLPIDKELCYENFVN"
     gene            22987..23583
                     /locus_tag="VUR43_001232"
     CDS             22987..23583
                     /locus_tag="VUR43_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5412920.1"
                     /translation="MKILLIDDHKLFSQSIKMILELSENIKKVQLVDNFSTISEIVFN
                     DYDIILIDINLTSLYQDDGLTLAQEIIDNGCSSKVVILTGYSKKMYEYRAKVMGAYGF
                     LDKSMNPDELVKKLKKIYLGGKVFSDEVMVEVLTPREIEMLELVRNGLTIDDICERIY
                     VSKRTVSNHLANIFSKLGVTNRQEAIHIAEQLGYFPPD"
     gene            23695..26649
                     /gene="lanM"
                     /locus_tag="VUR43_001233"
     CDS             23695..26649
                     /gene="lanM"
                     /locus_tag="VUR43_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HET5412921.1"
                     /translation="MSMVSEKWLSLFNNIEDDEQLDEFLKTTSGDSLQDWEVKFLQYE
                     QWGKDYIERELGTILYDEYNPQEKLRVSIHWLDLFKPICFKYLERLTSFLNKTQCITN
                     TNEFILEIESVFFEICMNMSYRTVVLEINDLRRASRLKGEDSKNRYNYFINTLLKDRD
                     YILEFYKKYPVLFELLDKKISNVLDYIEQIILHFEENLIDLESYFNYKNLKLSSIDFN
                     AGDTHSNGKSVCILKLNTKKKLVYKPRNMFIDVNLNLFSKEFAHRFGLSELLFVPKTL
                     SKDSYSFVEFIEEKECNSLQEVEVYYTNMGKLLAFLHIFGAKDYHGENILACQEHPYL
                     IDNETILHFSEPVNITSNAQNIYNFVTNSVYSVGILPMNLYSANNDKGMEIGALNSGE
                     RRESPYLSHQLANVGTDEIRIEKVFKIVGDFPSTVRYKGKNVSCSSYLNEVQRGFETI
                     YKIVLQNRNIVSRMIIKYFENCETRYIYRNTNIYVQFLETSHHPELLKNKYDFEMYLL
                     RLFEYGDVANLFDNVMMKDEVCQLRKGDIPIFYANTSSNEIYNGLGRYICALDGHSIA
                     NKVLNRITSLSDDNLLRQKRIINMAFMGSELFSKKFRVSEEHMNTETITSKIINRISS
                     AKFEFNNETSWLAMVAMNKSYEIYPMDCSLYSGTSGMILGITSIDDTRLRTLLPGVIN
                     YTNNYIKELQGNFPVHQLGAFTGVYGYLYTLCVLREEGTPFVEDIEEIIYETLSSTFR
                     QLRNIDNLDIIGGLAGILGVLIKIQKTMLDSSRVTELTQKLSEGVVQKILEKYKKDGF
                     WIENDPGYAHGNYGIITQLYRYSLSNTCKFDAKTSIISCIKEYLDKERSLLCGKNGFP
                     LRNNAKYYSWYNGIVGIVNAKNYLETNEFPDKFLKTEVQDYSIKILNQDSTLDNSICH
                     GSIGNLVILDSILGYSVDIENRIATESSSYLLDKETYECDDWGILTGEMGILMANDRK
                     SRTRLNDILLLN"
     gene            26662..28785
                     /locus_tag="VUR43_001234"
     CDS             26662..28785
                     /locus_tag="VUR43_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HET5412922.1"
                     /translation="MKRNIPFIEQHQKTECGLCCVAMVSNFYNHEISVKDLRNLKETG
                     RDGTSFQNLIELLENMGFKVKSFRFPKDRPDVYKQIKVPAIALWESKHFVVVEKVTSK
                     FVWVIDPELGKLRYDLNEFSAGFSEFLISISSSDRVIKQKSKENYGEIYAKLWQSWHY
                     FVPLLFLTFVSYAVSFILPIWTQQLLNQATGGNQFNPAILALNFIIFTLLYFIIMLGQ
                     RYLSINLTNDIDKRLNNSVIGRLFQLPYKFFSTRSSGDLIYSINGLGRIRQLFTNQVV
                     LGILDIGFVICILFYFLYIDFFVTIIALMLVVINLLLLLLTRKNLEQKSKSFVIAQND
                     LQNKQIEMIYSMMGIKMEGFEVRTFKQWKGYLDKYLYRYRASELFSSVVNSLFSIITF
                     ISPFILLFIMLLPDNHLGNKLGGIFAVYSLSSLLFGKINSIFDTIVAFYNSKTFLSRI
                     LEILGEETEINGVVKHDLNGEIALKNVSFSYTRDSKKVLSNVSIEIKKGEKVAIVGSS
                     GSGKSTLSKLLIGLFPASSGSILFDDLDYNLLDKQYLRQQIGIVPQDMTLFNKTIHEN
                     IAGDISVSEEEMTKICKLVNIHDEIMEMPMGYNTLVSEMGMNLSGGQRQRIILARALV
                     KKPKIILLDEATSYLDNVNENEIMQKFKEQNITIIVIAHRLSTIIDSNQIFVMDKGEI
                     VEQGSHTELLNMKNGLYKKLYQTDY"
     gene            28895..29536
                     /locus_tag="VUR43_001235"
     CDS             28895..29536
                     /locus_tag="VUR43_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET5412923.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELSS
                     QNDAMNQVYKDYILDYHFENADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPCELLVNQVQVWKSGLDDLDKATPKTLEESSSISSLPNTTTK"
     gene            29546..30043
                     /locus_tag="VUR43_001236"
     CDS             29546..30043
                     /locus_tag="VUR43_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001019161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412924.1"
                     /translation="MEIEECKQISILDVANRLGISFKQVSSRVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKEALAFLSEEPFQNEAVQEKRERPFYYPLKRV
                     EDSNCSLARYYLTECRGISEEIVQKMIQQGLIAQASWKTNETVEPVIVFKSFDHRHKL
                     QAASL"
     gene            30287..30451
                     /locus_tag="VUR43_001237"
                     /pseudo
     CDS             30287..30451
                     /locus_tag="VUR43_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237143.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase"
     gene            30565..31431
                     /locus_tag="VUR43_001238"
     CDS             30565..31431
                     /locus_tag="VUR43_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412925.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KSTATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
     gene            32023..32274
                     /locus_tag="VUR43_001239"
     CDS             32023..32274
                     /locus_tag="VUR43_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412926.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
     gene            32503..32805
                     /locus_tag="VUR43_001240"
     CDS             32503..32805
                     /locus_tag="VUR43_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412927.1"
                     /translation="MKNKYDVKRIIPDELSESLDIFLKNYSETGLSDYNTYLFYGFIL
                     KSYKLPRENRYSIKLLVKELQNRGLKVTLIINIYYHALNCLALNDGLKIYGEDFLI"
     gene            32802..34148
                     /locus_tag="VUR43_001241"
     CDS             32802..34148
                     /locus_tag="VUR43_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HET5412928.1"
                     /translation="MNYEKYLNYLDYETEIEDAYHNLLLEYKISDNFSDEHWLYNLPS
                     NITQSKGFKIHLSASILNANLVAKKFFDFIFSREKKINFKILVSIKELSLQNTGLNGY
                     SQVGKFITIYPKDNKEFQRLLHKLEILYKGVKGVNIPSDFRFQLSEVVYYRYGEFVKD
                     STFKDKRDKKIPSNVNVPIRDYYIPRYNTIPDQYIILEVISKNAKGGVYKVFNTQKRV
                     YSLLKEASDLSLVDFTNRDSVNRLINEREILVELEKEEFTPKVFNDFYIKNSYFVEFE
                     FIIADKLSEYNMVSGSYDWFLTLIDYMEIINSKYNLSYRDLSFNNILIDNRNNIYIID
                     FEHALRKETQIEEKKLPLFGTPGFYETNLNLLNNQPEDIMGLVLLLYWSQNLDDFNVF
                     SKMSFLEAMEYAMNFNSRRLDTLDKSDWLYDIYKKAFNYKYDTFSELKKDFIEVLK"
     gene            34162..35079
                     /locus_tag="VUR43_001242"
     CDS             34162..35079
                     /locus_tag="VUR43_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5412929.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFFGDM
                     RDFVDNSTIKLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENILDVINE
                     VGKACEIKNFSTSKLTLQESYLQRIGGEK"
     gene            35076..35876
                     /locus_tag="VUR43_001243"
     CDS             35076..35876
                     /locus_tag="VUR43_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5412930.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
     gene            36034..36507
                     /gene="tnpA"
                     /locus_tag="VUR43_001244"
     CDS             36034..36507
                     /gene="tnpA"
                     /locus_tag="VUR43_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HET5412931.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVLSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            36764..36985
                     /locus_tag="VUR43_001245"
     CDS             36764..36985
                     /locus_tag="VUR43_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5412932.1"
                     /translation="MYRRLRDLREDHDLTQKQIATILSFTNSAYAKIERGEHALTADV
                     LVKLSDFYDASTDYLLGLTDFPDKIRFRK"
     gene            37287..37520
                     /locus_tag="VUR43_001246"
     CDS             37287..37520
                     /locus_tag="VUR43_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5412933.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            37596..39104
                     /locus_tag="VUR43_001247"
     CDS             37596..39104
                     /locus_tag="VUR43_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5412934.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKREARKRLDAKFLEIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRAIKRNQEFEAYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEEKLL
                     KNCQKDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     ISRSQENTVTALNQFVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFK
                     DLLHLGSRYSPKHIVSNLLLKIKKDIVKYHPQFDIKIVKLSGNQIKGFSISW"
     gene            39186..40037
                     /gene="ylqF"
                     /locus_tag="VUR43_001248"
     CDS             39186..40037
                     /gene="ylqF"
                     /locus_tag="VUR43_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET5412935.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            40024..40803
                     /locus_tag="VUR43_001249"
     CDS             40024..40803
                     /locus_tag="VUR43_001249"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET5412936.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGATPIHRTSFEPVKSLVLGKKES"
     gene            40819..42369
                     /locus_tag="VUR43_001250"
     CDS             40819..42369
                     /locus_tag="VUR43_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET5412937.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFLGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            42955..44025
                     /gene="xerS"
                     /locus_tag="VUR43_001251"
     CDS             42955..44025
                     /gene="xerS"
                     /locus_tag="VUR43_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET5412938.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT        14820 a         6701 c         8661 g        13884 t
ORIGIN      
        1 ttttggttga atgtctaaga ccagttcatc aggtggatct tcaaattatt gcaccagcgt
       61 ttaagaaata ttttcaacag aatcaaattc atttacacaa attattttat tatgcccaac
      121 tatttaaagt aactgataag ttacaatctt atacggaggt gctatcttaa tgttttcaaa
      181 tgcgaatagc tttaaagcaa aaatcaaaaa tatttcaaaa gataagggaa ttccagctca
      241 acaagtacaa caacattatt taattgagca agtgttaaag ctgatttcta ctagttctta
      301 tagagattcc ttcattgtaa aaggagggta tctaataggt caaatgattg gactagataa
      361 gcgaaccaca atggatttag atgtcactct gaagggaacc gaaatgagca gagaaaattt
      421 gattgatatc tttgaagaga ttctttgttc taaaactgat ggtttttcat tttcagtaga
      481 taagctagaa cctattcgcc aagatgatga atatggagga ttttcattaa aattaaatgc
      541 aacttttgat acattaaagg aggttgtttt tattgatatt actactggtg ataagatcac
      601 accaagagaa attacttatt caatgacttc tatctttact aatgaaagca tcaagatatg
      661 gacatataat ctagaaactg tacttgctga aaagttagaa acaatcatta gtaggggatt
      721 agcttcaaca cgcccacgtg atcgatatga tcttttcacc ttgtataaac ttagaaaaga
      781 agagattaat cttgaagtat taaaaaatgc acttgaaaat acagcaaaaa aacgtaaaag
      841 taaagatact atttataatt gggaagaaca agtgagagga attgaaattt ctgattatca
      901 gaaagagcta tggattcgtt atcaacgcca atttaagtat gctaaagata tctcattatt
      961 caaagtgtca tggacttgac caaaagagat acccttgata tgaagacatg gggcaaggaa
     1021 aaatcaatgg tttacttagt tatcccagat aatgatagta cctttcgctt tctttcagcc
     1081 ctcttttttt caaccgtatt tcaaactcta acaagacaag cagatattga ttttaagggt
     1141 caattgcctc ttcatgtgag agtttactta gatgagttcg caaatattgg agaaattcca
     1201 gattttgctg aacaaacctc aacagttcgt tctcggaaca tgagtctcgt tcctattcta
     1261 caaaatattg cccaacttca agggctctat aaagaaaaag aagcttggaa aaccattctt
     1321 gggaactgtg atagcttagt ctacttaggt gggaatgatg aagatacctt taaatttatg
     1381 agtggcttac tcggtaaaca aaccattgat gttcgaaata ctagtcgttc ctttgaccag
     1441 acaggttcag gatccctttc tcatcaaaag attgctcgtg atttaatgac acctgatgaa
     1501 gtcggaaata tgaaacggca tgaatgcctg gttcgaattg ccaatatgcc tgtctttaaa
     1561 agcaaaaaat acaattccat caagcatcca aactggaagt acctagccaa tcaagaaacc
     1621 gatgaacggt ggtggaacta tcaaatcaat cctttgaatc aaagacaaga aaatcatctt
     1681 gaaggcctta gaattcgtga tttaactttt gaatctagtt taaaataaaa atagaaaaga
     1741 ggaaatagat gattacgcat tttaaaggtt tggtttatgg agtagacgca agtgccatgt
     1801 ttgcacaagc tatgtctttg ttacagaagg gattgattgc ggttggtgcc tttctcgttg
     1861 ttgtagggat tgtcaacctt gcaaccaata ttaaagatgg tggaccaggt gttcggaatg
     1921 ccattcttga aattgtcggt ggtgttatgg tcggggctgc tggagccttt gtaacccaga
     1981 tttcaattta ggaggataaa caatgacatg aatcttagtt tagtctcacc ctttgtttac
     2041 cttgcatctg aaaaaatatc agctgaaaat ttatttgaag gatttaatgt ggatttacaa
     2101 tctacggtag atctgattaa atctctatct agctacaatc caacagtttg gacttatatg
     2161 tctagtatta ctaaaagtgt catgcagcct cttggagttg cgattttatc agttgttctc
     2221 atcctagaat tttcgaagat ggcaaagaag attgctaact caggaggagc gatgaccttt
     2281 gaagcattag cgccgatgtt gattagttat attatggtcg cagttgtaat taccaacact
     2341 accgtcattg tagaagctat catcggtatt gcgagtcacg ccattgaaca agtggcctcg
     2401 attgtggctc acggtggggc aaagtatgat acaatctctg gattaaaagg ttcaggattt
     2461 attggccgga tgattgtggg ctttttcgcc ctcctcattt ggctagttcg gatagtaagt
     2521 gcagccatgg tcaatctttt ggtatctatt cgatttattc aactctacct tatgattcca
     2581 tttgcccctc ttacgattcc aacattttta agtgatgaat ggaagtctat tggtattggc
     2641 tatttaaaaa atattatggt ctatgcggta caaggggttc ttatttttct gattgtttct
     2701 cttgttcctt tgtttgaatc tgctgggaaa atagctgttt caaatggtgc aggagtcttg
     2761 caatcacttg cgattatgtt tggtagtttg gtacaagcta tcttgctgat tatcgctctc
     2821 gttggttctc aacgtacggc tcgctcaatt ttaggtatgt aattagataa aggctaggaa
     2881 gtgattgctt cttagccttt ttagaaagga aagtcatgaa tacacgtgtc tttaaagaca
     2941 tctcaaaata ccaacacagg gcttggttag gcttcaccac aagacaaatt atctttgttt
     3001 taccagcctt tattgtcaca attattgttt tgggcttgaa tctctttttc tggcaatttg
     3061 gagattggtt tgtttacggt tttgtgtttg cctttaccat ccccctcatg ctttttggag
     3121 tctataaacc caatgattta tattttgaac attatttgaa ataccgtctt cattttgaat
     3181 taacggttcc cctacgcaca attacaggaa agaaaggacc tgaacatgaa aagaaaatca
     3241 aatacattaa agaaacaaaa aacttcaatg actaataaaa aagaagtagt taaagggaaa
     3301 aaagaggaag tgttaccctc tacggcgaat actctttatt atcaagccct gtatcaaaat
     3361 ggtctaatgc aggtaaaaga agattatttc tcacaaagct acttacttgg tgatgtcaat
     3421 taccaaactg ttggtttaga agataagggc gcaatcattg agaagtattc tgatttgatt
     3481 aactccctag atgaccaaac caacttccaa ttgaccatct ttaataaaag attgaattta
     3541 gaaaagttta gacaaagtgt tttgtatgag gaaaaagaag atgggtatga tagctatcgt
     3601 aaagaattga atcggatgat gaatcagaat ttagacagtg gtgaaaataa cttttcagct
     3661 gtgaaactga ttacctttgg tagaaaggat tctaatccca aacaagccta tcgttccttg
     3721 tcccaaatag gagaatattt caagagtggt ttctcagaaa ttgatgctcg ctttgaatcc
     3781 ttggctggag aaaaccgtgt gaacttgttg gcagatatgc ttagaggaga acaccatctt
     3841 ccgttttctt accgtgattt aacgagatcg ggtcagacaa ctcgtcactt tatagcgcct
     3901 aatctcttag atttcaaaaa caagaattac ctacaaatca atgaccgctt attgcagatt
     3961 gtctatgtga gagactacgg catggaatta ggggatcagt ttattcgaga cctcatgcaa
     4021 ggagatttgg aattgattgt gagcctccat gctcaaagtt cgaccaaagc agatgccatg
     4081 aagaaactac gaacaaagaa gaccttgatg gaatcccaaa agattgggga acaacaaaaa
     4141 ctagctcgta caggtatcta tttggaaaaa gtaggccatg ttttagaaag caatatcgat
     4201 gaagctgagg aactcttaaa aaccatgaca gagacaggag ataaactgtt tcaaacagtc
     4261 tttttgattg gtgtttttgg tcaggatgaa gaagaactca aacaagctct agatacgatt
     4321 caacaagtgg ccggctcaaa tgacctaatg attgataaac ttccatatat gcaagaagca
     4381 gcctttaata gtttgctgcc atttggttgt gattttttag agggagtatc acggagttta
     4441 ttaacatcta atgtagcagt gaactctcca tggacttcag tagatttaca agaccgtagt
     4501 gggaaatatt acggtatcaa tcaaatatca agtaatatta ttaccattga tcgcagccta
     4561 ttaaatacac catctggtct aattttaggg acatctggag ccggtaaagg gatggcaacc
     4621 aagcatgaaa ttatcacgac aaaaatcaag gaatctggtg aaaatacaga aattatcatc
     4681 gtggatccag aagcagaata cagtgtcatt ggacgagctt ttgggggaga aatgattgat
     4741 attgcgccag attcccaaac atatctcaat gtccttgact tgtctgaaga aaatatggat
     4801 gaagatcctg taaaagtaaa atcagaattt cttttatcct ttatcggcaa gttattggat
     4861 agaaaaatgg atggaagaga aaaatcgatt attgaccgag ttaccagact cacctatcag
     4921 tcatttaaag agccttcttt ggaagaatgg gtctttgtct tgagccaaca accagaagaa
     4981 gaagcgcaga atttggcact tgatatggaa ctgtatgtcg aaggttctct tgatattttt
     5041 tctcataaga ccaatattca gacaggatct aatttcttaa tctataatgt taaaaagtta
     5101 ggagatgagt tgaaacaaat tgctcttatg gttgtttttg atcagatatg gaatcgtgtc
     5161 gttcggaatc aaaaattagg gaagaagacc tggatttatt ttgatgaaat gcagcttctc
     5221 ttattagata aatatgccag tgatttcttc tttaaattgt ggagtcgtgt cagaaaatat
     5281 ggagccagtc cgactggaat aactcaaaat gtcgaaacct tattgttaga tccaaatggt
     5341 agacggatta ttgccaatag tgaatttatg attctcctca agcaagcaaa aaatgaccgg
     5401 gaagaactgg ttcaactctt aggcttgtca aaagaactcg aaaaatacct agtcaatcca
     5461 gaaaaaggag caggactaat aaaagcaggt tcagttgttg ttcccttcaa aaataagatt
     5521 cctcaaggta ctcaattgtt tgatattatg agtacggatc ctgataaaat ggcttctaat
     5581 taaggggaag tggaatgaag gataaaagag aaattatacg tgcccgaaag gcatttagaa
     5641 gaagtttaaa agatgagaag aaattcttga aacaaggaaa gaaggaggtg agaaaacaga
     5701 aaaaagattc cgctgtactg gatgaaaacg catggaaaaa agagataaaa gaaaagctag
     5761 aggagatgag agaagcttca aaggccaaag taaaacaagc aaatgaagat tataatcata
     5821 ttcttcaaaa tagtcctcca tctcttttga atcggaaaga attaagagac agacggttgc
     5881 ctcatgctag gaaacgattg aaaatagcca agaagcaatt taaggaagca aaggtagaag
     5941 caaaatcaga aagaaaagag agtcgtaaag aaagaaaaac caaccaaaaa tttctttatg
     6001 gtcaggaatc gaaagcaaaa tctaactttt tctttcacgg gaagaatcta gaagaactaa
     6061 aagctaagaa agaagtcaag gtcgcaaaag agaatctaaa atctactaaa caagcctata
     6121 agtccaagaa agtcagtagg aaagcaaaaa cttttcttta tgtccttgga cgtgaaggag
     6181 gagagttagc ttcagaaaat gaagatttag aaggttatcg cacgcttcaa gagaccatta
     6241 gaaaaggaaa acgctacagt cggctttctt ataatcttgg aaaagctagt gtcaaaacag
     6301 gacaagcaac aggtcgtttt accaagaaaa gactgaccaa cacaaaagag cgataccatc
     6361 attttaagga tggaaaagga tggaaactag cgaaagagaa tccaagttcc tttaaaaatc
     6421 ggtttcgaaa attaaagaaa caaggtctta caagtgtccg aaatatctat caaaaactaa
     6481 aagcagcctt ttccttcttt acatttgcgg ctggaaatcc tgcaacatgg atagttggag
     6541 gattagtctt tcttctctta cttatgatga gcttcttttt aggattttca tctgctagtt
     6601 tgattcaaca agatgaattt gaattgacta aagcttatac ccacctaact tgggaagatg
     6661 cagaacatac tcgaacaaat gataaaggca ttacttatta cacaaaagtt gatgatgtga
     6721 tggggtatat gaactttaaa ttccatgact atgagttaca caaaccagtt tacttattta
     6781 gttcagaaac ttacaaggat tatctgtcta ctttgtggca tgatttaaac gatggtgatg
     6841 atttgaaatc catgcaagac ctctatgaaa ctcctaagta taaactatcg aaagacgatc
     6901 aagaggaaat aaaggaacta aaagaagaag gtgtgtatgc ttccatgcag gaattagaca
     6961 atccatttga gggacaaagc aacgaagata gtctaaccat gacttatcgt tatggatact
     7021 atgatttaga tggaaaacct actcttcagg agtacatcct actagaagca aaggctcacc
     7081 aaacgattgt cgcaccaatg gatggagttg tatctctaga tggtgacaat attattctca
     7141 ctaacggaaa aggagagaat gagagtcgat tgaccttgca ttctattcat aatggccgtg
     7201 cgattgaggg gacaagagtc ctaacgggtg atgttattgg tgaaacacca gatgatacag
     7261 gtttgaaagt ttcctatcaa aagtataaga acaagaaaga aaaattggtg tatgtcaatc
     7321 cgcaatttta ttttccaaaa gtcattcaac ttcagacaac tatcttacct gccattggtc
     7381 agtttggtgg agatgagttt gaacgagcaa aacatattta tgagtttttg aaatctcaag
     7441 gggcaagtcc ccaagccatt gcggctattt tagaaaattg gtcggtagag tcttctatta
     7501 atcctaaacg tgctgaagga gattacttat ttcctcctgt tggcgctacc gattcctcat
     7561 gggatgatga aacctggtta gcgattggag gtccagccat ttatagtggt gcttatccta
     7621 atattcttca tagaggtttg gggttaggtc aatggacaga tactgcagat ggttcaacac
     7681 gtcatacagc tttattgaat tatgcacacg ccaaaaataa gaagtggtat gatttagacc
     7741 tccagcttga ctttatgctt catggagata gtccttacta tcaaagttgg ttaaaggatt
     7801 tctttggaaa tacgggcagt gcggcaaatc tcgcccaact ctttctcacc tattgggaag
     7861 gaaattctgg tgacaaacta ctggaaagac aaaccagagc aacggaatgg tattaccaaa
     7921 ttgaaaaagg ctttagccaa acaaatggag gacaggcaaa gagtgacccg caatcccttg
     7981 aaggggttcg tggagacttg tatgatcatt ctgttcctgg tggtggagat ggtatggcct
     8041 atgcctatgg acaatgtaca tggggtgttg cggctcgtat gaatcaatta ggcttaaaat
     8101 taaaaggaag taatggagag aagatttcaa tcattaatac catgggaaat ggtcaggact
     8161 gggttgcgac agcttccagt cttggtggag aaacgggctc tataccaaga gcaggtgcta
     8221 ttgtttcttt tgtgggaggt acacatggca caccagcaga ctatggtcat gtggcttttg
     8281 tcgagaaagt ttatgatgat ggctctttcc ttgtgtctga gacaaactat gggggtaatc
     8341 ctaactatac ctttagaaaa atctctcaag cagatagtgc catcagtttt gcctatacta
     8401 cgaaataaaa gaatcatgtc atcagtttag gtgacatgat tcttattttt tatagagcga
     8461 catatttaat gccataggct gataacttac ttgatgatca tctttaatca attgactgta
     8521 agcaacaaat ccgaactgtt tataaaattg aatgacttta ggatgattga tactatctaa
     8581 aaataccatc tgagttccta caattgctcg aaattcttca attttttgaa ttacaatttc
     8641 aaataactct tgtcctgata gtttatttag ctttgtgttt ttgccgaatt gaccgataag
     8701 taacacaagt agataatcaa tatttttggg acttttccct tttaggacga gtttcttttt
     8761 ttaggatttc tctaaatcag aaatatcaac aactttgaga gataaactaa agaatcctat
     8821 gatgttattt gtttcagttt cttcaacgat aaaattacga gaacgatgtt gtttttcaaa
     8881 attgggagct ttatcagata gataagtcaa catctcttca ttaccgttga aattaacatt
     8941 ttctaaaatg atagttttaa atagctcctg aacttgtttc tcagttttat caggagccag
     9001 cacttgaata ttttcaagat attgtttaag tggtgttact tgaattgtca tcttacagat
     9061 actttgaaat gagtttattt ttcgttggag cggtagcgtt ttgtgattca atagatttca
     9121 agactgcttg tagcttttta gatggtttat gattaagaat ttttagagca tcttcgtttg
     9181 ttagttttat atcacgtgtt aaactgattg tagccatttg ttctacctcc tgtttctact
     9241 taaattcatt atagcttatt ttgaacaaaa gttcaatcta aagatagtgt atgttttcta
     9301 tagtgtataa atccaaaata agtttttctc ttgcatttgt agctcatatt cgttagaata
     9361 atggtgtaaa tgagtggtcg gctcatggtc aatctgatag taatcttgga cataagggcc
     9421 aagcggtggc ggacaccaga acgaaatccg atagcaatct tggacgtaag ggccaagcgg
     9481 tggcagacac cagaataaac tgactaacta ggtggcttac aggttctgta agtcatcttt
     9541 tttactttga tagtaacgtt ttatcatttt aaggagaacg cagttttggc tcgttctctt
     9601 tttttgttgt gatacttctt tcaaggaata tttggtagga ttggagtgaa aaaagattaa
     9661 ctaggaaaga aggaagtata tggaaaccat ttatcaacgt gattcggatc aagatggact
     9721 gactgatgct caagaattgg cgctaggaac caatcctctt agcgcagatt ctgatggtga
     9781 tggacgttca gatttagtgg aagtagaaga aggaagcaat cccttagaaa aggattttca
     9841 agacatagac caaacaagta taactgaacc gtcatcagta tttatggaaa tgaaacaaaa
     9901 gatttcagat atgatggaga gtcaccacaa ggaatttata caggttctga ttagtattga
     9961 aacagggatt gaaaacgaac aagaccttga agacttatat acttactaca tgagaacaga
    10021 tgccgtttct cttttgtcta gtgatttaga aaccagtcct caagaggttg aaatggagat
    10081 agagttgtag gggaatcatg tgattctcct attttcgtat agatgaaagg agcaagtatg
    10141 gaagtaatgc aattattggc tatgtttcgt ggaacaattc caaaagatag ggagaaaatg
    10201 accctatttc ttcgttatca agcgcaacat tttgatgaga aatggcagga cttggtagag
    10261 aattttttga ctgaagaggg caagatagaa gagattcctc acgtctattc ttttgatcaa
    10321 gatattgttt ctttcctaga ggctagttct gaaaataatg accaagattt agaaagttac
    10381 acaagaaatt ttggacaagc gggtctagat aaattatctc aattaagtag ttgggagaaa
    10441 tacttggtgc tagaagtcgc aacctataat ctttccactc gattttacat ccaatctgaa
    10501 aaagagaagc tagaacaact aagtgagctt atctttcatc agaatcagga tgtcaatttg
    10561 gtcaatgtct atcgggttgc gaataatcta tctgaccgta ttagtagaga tatagaggaa
    10621 tttcttctaa tggttgactc aaaagaacta aaaaaagagg ttcttgagat tcattttgaa
    10681 gaaaaagagg gagatgttct agcctatttg ggttcagaat taatggctac tttagatacc
    10741 gttacggatc ttgtccatca tgaagaaaac taccaacaac tcccactgac acaaaagctg
    10801 aagattatta ctcactttga tgatgtaaaa gctaaaatcg aaaagtctaa gcaagtagcg
    10861 gaagcggtct tacctttaga taatattgag caggtagaag aaaatgtgga agttcattcc
    10921 ctatctaaag tagataaaat tgtagaagaa gccttgaggg aatatccaat cggttcacaa
    10981 gtaagttata aaggacaagt atttcagttg gtttcgattg aaaatgcaca gttaaatgac
    11041 ttagttcgcc tagagctatt caatgattcc aaccagttat ttgaagaaaa tcctatttta
    11101 tatttgaaca gtttggaaga gattgaacaa gtattgtctc tggtagaact tgaaaaagaa
    11161 gattcagaga ttgagattga atcaccaagt gaaagccagg aaatagattt gttttcctat
    11221 ctggaagaag aaaatgaaaa agataaggat aaggaaacag aaacgcttat tgtaggcata
    11281 gaagagacgg atgtccctgt tctagatttt gtttttccag atgatttaga ggacttttat
    11341 cctaagacaa atcgagaaaa gattgaaacg aatatcgccg caattgaact tgttaaaaga
    11401 ttagaaaaag agggacgaca agcgaatcca aaagaacaag agctactagc taagtatgtc
    11461 ggctggggcg gtcttgccaa tgaatttttc gatgaactca atccaaagta tgaaacagaa
    11521 cgtttaactc ttaagagttt agtaagtaaa tcagaatact ccactatgaa acaaagttct
    11581 ctcacagcct attatacaga cccaatgatt attcgccaga tttggcaaaa gttactggat
    11641 gatggttttg agggaggaag gattttagat ccttctatgg ggactgggaa cttctttgcg
    11701 gctatgccta gaagtatacg agataaatca gaactctatg gggttgaatt agacagtgtg
    11761 actggcgcaa tcgcaaaaca actccatcca aatgtccata ttgaagtgcg aggatttgaa
    11821 gaagttccct atcaaaataa tagttttgat ttagtcttaa cgaatgttcc ttttggaaat
    11881 tttcgcattg ccgataaaaa ctatgataaa ccttatatga ttcatgatta ctttgtcaaa
    11941 cactcacttg atttagtaag agacggagga caagtgtcga ttatctcatc tattgggaca
    12001 atggataaac ggacagataa tgtcttacaa gagattaaat ccaacactca ttttttaggg
    12061 ggagttcgtt tgccggatac ggtttttaaa aagattgcag gtactcgagt gaccacagac
    12121 ctcctcttct ttcaaaagga tcaagcaaag aatcttaatg aagaggaact tgtctttagt
    12181 ggctctattc tctttgagga ggataagcgt gtctggatca atccttattt tgatgggaaa
    12241 tacaacacac aagttttggg tgaatatgag gtacgtaatt ttaatggagg aaccctcaat
    12301 gttaagaggg tatcagaaac attagctact gatataatgg aagcattaga gaatgtggaa
    12361 gcacctaaac aaattgacaa ttctttgaaa gcacctgttt ttatccaaga agaagtggat
    12421 aattctgtcc caagtcgtat acgtgaggac ttagcgctct attcttttgg atatgagggt
    12481 aatcaaattt attaccgaga tacgcatggt attcgaaaaa gttcaaaagt agacgaaatt
    12541 agttattatg tagacgagaa gggagatttt aaagcctggg acagttcttt gtctgaacat
    12601 aaaatagacc gattcgtgca acttcatttg acagatgagg aagcactaga tgtttacaag
    12661 tcagaagaag cgagtaaaag agggaaatat aagggactgt tcaaaaaaac tgtcttttat
    12721 gaaagtccct tatcggataa ggatattagt cgcattaagg gaatggttga tttgagagag
    12781 acctatcaat ccttaattga aattcaacgt catcaagatt atagtcggac agattttcag
    12841 gtgttactta gtaaactcaa tcatgactat gaccgctttg taagtcaatt tggatacttg
    12901 aatgcctcag tcaatcggaa cttatttgat agtgacgata agtattcctt actagcaagt
    12961 ttagaagatg aatacattga ttctaaaagt cagaaagtaa aatataaaaa atctttagcc
    13021 tttgagaaag cattggttag gccagagaga gtgattgcaa gagtttcaac ggctctagat
    13081 gccttaaact ctagtttatc ggatggtaga ggggttgatt tagactatat ggtatcaatt
    13141 tatcctgaac atagccaagc tgctatttta gatgagttgg gtgaccagat tttaatggat
    13201 ccagaaagct atttaagagg agaaagaaaa tatctttcta agaaccagtt tttatcagga
    13261 gatattctca acaagataga agtagttcaa ctgttagtag aggaaaacaa tcaagattgt
    13321 gactggtccc atgctttaga tttgttagaa tctgttcgcc ctccaaggat tcatctggca
    13381 gatattgagt ttaaaatagg gtcacgttgg attcctcaat ccgtttatgg taaatttgct
    13441 tttgaatgtt ttaccaatcg tgaatttgaa ttgtcttcgc ctgatgttga acaagtcatt
    13501 gaagtgaatc ctgtcgatgg ccaggttcat ttaaggacat catttgctta tcgctatcca
    13561 agtgccaaag atagtagtct tggagttagt gggtcacgtt atgatacagg aagaaagatt
    13621 tttgagaatt tactaaattc gaaccaaccg acgattacca tgactgttac ggaaggagaa
    13681 aagaaaaaga ccatcacaga tttggaaaaa acctctgttc taagagcgaa agagcagcat
    13741 ttacaagaac tctttcaaga ctttgtctca cggtatccag acgtccaaca agtcattgaa
    13801 gaaagttaca atcgtcttta taatcgaacg gttagtcgag agtatgatgg tagccattta
    13861 gtcattgatg gcttggctca aaacattagt cttcgtcctc accaagagaa tgccattcaa
    13921 agaatcgtag aagaaaaaag agccttgtta gctcatgagg taggttcagg aaagaccttg
    13981 accatgcttg gtgctgggtt taaattaaag gagttgggga tggttcataa gcccttgtat
    14041 gtagtgccct ctagtttgtc tgctcaattt ggtcaagaaa tcatgaaatt tttccctact
    14101 aaaaaggtct ttgtgatcac taagaaagat tttgtgaagg cgagaagaaa acaatttgtg
    14161 tcacgtatta ttacaggaga ttacgatgcc attgtcattg gggattctca atttgaaaaa
    14221 atccctgtca gtaaagaaag acagatgaat tatatcgagg ataaactcaa tgaactacga
    14281 gagattaaaa cacattctga aaataagtat actgtcaaag aagcagaaca atcaataagt
    14341 ggtctagaga aacaattgga agaactccaa cgctttaatc gtgatagttt tattgatttt
    14401 gagaacttag gaattgattt tctctttgtg gatgaagcac atcactttaa aaatattcgt
    14461 ccaattactg gacttgtaaa tgtagcaggg attaccaata caacctctaa gaagaacgtg
    14521 gatatggaaa tgaaggttcg acagattcag gaagaacatg attttaaaaa tattgtcttt
    14581 gcgacaggaa cacctgtttc caattctatt agtgagttat atactatgat gaactatatt
    14641 caaccagata tcttaaaacg ctatcaagtt gattattttg actcttgggt aggtgttttg
    14701 gagaaattca aaactctatg gaattagctc ctacagggga taagtaccaa cctaagaaac
    14761 gatttaaaaa gtttgtcaat ctacctgagt tgatgaaaat ctataaagaa acagccgaca
    14821 ttcaaacaca agatatgttg gatttacctg ttccagaagc tcatattatc cctattgaga
    14881 gtgagttaac tgaaaaccag aaactctatt tagaagaatt ggttatgcgt tcagatgcgg
    14941 tcaaatgtgg gacagttgat ccgagtcagg ataacatgtt aaaaattacg ggtgaggcac
    15001 gaaaactagc aattgatatg cgtttattgg actctagtta tagtctagca gacaatcata
    15061 aactgcttca ggtagtggat aatgttgaaa gaatttatcg tgaaggaatg gaaaataagg
    15121 ctactcagat gattttttca gatattggca cacctaagaa aaaggacaat ggctttgatg
    15181 tttattctga gattaaggct ttattagttg atagaggaat ccctagtaag gaaattgcct
    15241 ttgtacatga tgccaatagt gatgaaaaga agaatagttt gtctcgaaag gtcaatgcag
    15301 gagaggttcg gattctcctt gcctcaactg aaaaaggagg aacaggttta aatgttcaga
    15361 gcaagatgaa agcagttcat cacctggatg tcccttggag accaagtgac attcagcaac
    15421 gcaatggacg gattatccga cagggaaatg aaaacaagga agtggatatt taccactaca
    15481 ttaccaaagg ttcatttgat aattatctat gggcaactca ggaaaacaaa ctccgctata
    15541 ttaagcagat tatgacttct aaggagccaa ttcgtgctgc agaagacatt gatgaacaga
    15601 ctatgacggc ttctgatttt aaggcgctag caacaggtaa tccttatctc aaatataaga
    15661 tggaattgga gaatgatcta accctattag aaaaccaaag acgcgcattt caacgcagca
    15721 aggatcacta tcgtcataca atctcttact gtgaagaaaa tatacccatt cttgagaaac
    15781 gattaagcaa gtatgaaggc gacattcaac agtctgaaat atcgaaagac caggcatttt
    15841 ctatgacagt aggaaagcaa gtttttgagc agcgagctga agcaggggaa gccctacacc
    15901 gtcttatccg tcataatcaa gctgacagca aagaatttcg taccctagca agctatcgag
    15961 gatttgacat taaaatgctt agtcttccaa ccaatcaacc tcttcctgaa accttctctg
    16021 ttaagattgt aggagaaaat cagtattctg tcagtttaga tttgtattct cctttgggga
    16081 caattcaaag gattcagcat acgattgatt acatcaagga ggaccaagta aaaacacaga
    16141 acttattgga tgaattaaag gataaatgga ctactgctaa ggtagaaatt gagaaaaatt
    16201 ttccaaagga agaggagtat caaactaaaa aggccgaata cgatgtactc gcaccattga
    16261 ttgaaacaga aacggattta gatattattg atcaggcatt aaggcaattc cacgaaaaag
    16321 gaaaagaaaa gcaggaacaa ctttcttttg aattagatta aaaaatatat aaaaatagcg
    16381 gacaagaaaa gaaaagcgcg gtagaataaa gatagaaaga aacgaggtaa cgattatgat
    16441 ggaagatacc tattatcaat tagaagaggc cttggtacag ggatttcaaa cacctgaaga
    16501 atacaatgcc tacaaggaat taaaggaaca ttatgaggaa gttactgggg attacagttt
    16561 ttctaaacga gaactcacta gtcaattgga aatctctctt cagaatcatc gaggtgtgga
    16621 ctttgaagaa catgaaaaag aggagtattt ggacttagtt caaaaattag aagagtttga
    16681 ttcctctctt gccacccatt atcgtcaatt gattgactag aaaggagaaa gttatgaatg
    16741 atttactcct tatcccagta atttttttag cagttggagg aattctcatt cttttatgga
    16801 gactctttct tattgccagt ggacttttcc tgattggttt tgtcagtttt cttattttca
    16861 tagaggtcta tggaatttat ctgttcttta ctgaaccgac cctttatata gaagatttat
    16921 cccagaatgg tctgatcagt tttacaggat tttatgtggt atttaatcta gccttgcttg
    16981 tatgtggtgt tttgaaaatc attagttgga caagaagatt aaaaagtagc tgagcaagag
    17041 attgttcagc tactttttaa ttgggcacta taaaaatttt tctcgaaaat aagaaacttg
    17101 cacgatttac tcattactta gccaatacta gagtttatac tagttactgt aaagatgatc
    17161 atctaaaaga aggaaggagg taaccttatg tctaaaaata caagtcgtcc agagattgat
    17221 tctctaagtt tcgaggttga aaaccaagaa ctttccggta aatcaggttc tggttggttt
    17281 acagctgttc aacttacatt ggcgggacgt tgtggacgct ggttcacagg ctctttcgaa
    17341 tgcacaacga acaatgtgaa atgcggatag cctagatttc gatactcatc aatttgaaaa
    17401 tgaaatttta agttaatata aatttgtaga aattaaactg tttttaatga ttcttttact
    17461 taaattttca ttttctttgg agagtataga aataggttta aaccatagtg agtaggagta
    17521 gaagaaaatg agaaaaaata acaatcataa agaaattgat acacttgatt ttgaagtaaa
    17581 aaaccaagag ctttctggta aatcaggttc tggttggttt acagctgttc aacttacatt
    17641 agcaggacgt tgtggacgtt ggtttacagg atcttatgaa tgtacatcaa ataatgtgaa
    17701 gtgtggctag tttttctcac tactaaaaag tttgatgtag atttgtttct ataggattca
    17761 tttttcaatt tgaaacttgt tatagtcctt tggtttgaga gtagactgaa ggactatata
    17821 caaggtttac ggaaaatata aacggaacga aagaaattta cggagtaaaa tcatgaaaag
    17881 taaaaaagta aatactgaga ttgatacgct tgaatttgaa attgacaatc aggaactcaa
    17941 tggcacctca ggatctggct ggtggtacac agcttttaaa atgacactag caggtcgctg
    18001 tggattgtgt ttcacctgtt cctatgagtg tacgacaaat aatgttcgtt gttagataaa
    18061 acaaaaggaa aattctagta ttttattaca aaacattgac aacactttga tttagtgtta
    18121 tatttacaag gagaaataca aatgaaacaa gacaactttg agattgattc tttggattat
    18181 gaaattaata gtcaagagtt gaatggtaaa tctgctgcag ggtggcgtac ggctgttaga
    18241 ttaacagtac agggtcgctg tggttggtgg tttacatatt cttatgaatg tacttcgcca
    18301 aacgtgcgct gtggataaaa ccacctccat tctttgagag gaggataaaa tggaaggaat
    18361 tattggaaca ctaggcttct atgcacctgt actggtctta ggagttattg tcatagggat
    18421 tgtttacttt atgaaaaaaa gaaacaatcg aaaataatca atatcgaccg atacctaaaa
    18481 aagtatcggc tttttttata gcgtaaatat attgcacaaa atactcatgg caaaccttga
    18541 aagaaaccgt ataatgagag tgtaaaaaag aaacggagga atgaaatgat gaaacagctt
    18601 attgtgacag gattaacgaa aatatttggt caaggggata atatcgttca tgctttatta
    18661 gatgtgaact tgtccgttga aaaaggtgaa tttctggcaa ttatgggggc tagtggtagt
    18721 ggaaaaacaa cacttctcaa ctgtatttca acgattgata agccaacatc aggtgagatt
    18781 cgatttgaag attttgacat catccatgcc aaggaaaatg aactagctga ctatcgtgct
    18841 aaaaacattt cctatatttt ccaagcttac aacttggtgg aaaccttgac ggtctatgaa
    18901 aatatcgttc tacctcttca aattcagggg aaaaatatca aaaaacatca ggataagatt
    18961 gaggaaattt tggataagtt ggccatccaa aacttaaaag ataagtttcc taatcagtta
    19021 tcaggtggtc agcgacaacg tgtggcaact gctagagcct tgattgatga ttctaaactg
    19081 attatcgcag atgagccgac aggagccttg gactctgcca attctgaaaa actgatggca
    19141 cttttgcagg aaatcaataa aagttttggt attaccattt tactggttac gcatgaccct
    19201 gccgcagcca agtactcttc acggatggtg ctacttagcg atggaaagat tatggatgat
    19261 ttggaacgta acagcttatc taatgaacag tatttgcaag agatatacag ccgtgccaga
    19321 taggaggagg agagtatgta tccaaaattg attttacgaa atgtatttcg aaatttacag
    19381 acctatacca tctatttttt cagtctgacc ttgatttata gcttgctcta cgcttttaat
    19441 gctttaccaa gccatccagt gatgcaaagt ttatcaggag caaaggaaat gttaacgacg
    19501 gtgatgagcc agtacatggg cttgctttcc tatctgattc tatcggcgat tgcctttctc
    19561 gtcgtttatt ccacaaactt tgtcctggga cggcgcaaga aagagctggg actttatgca
    19621 acgttgggaa tgaagaagaa gcagattatc cgtaccctgt tctttgaaac catgctggtc
    19681 aatatctttt ccttgattct aggtttcttg cttggagtga tcttactggt cattctagct
    19741 aagattgcat ctgagttttt tatggccaat tactttggta gtctgctttt ctttgatagc
    19801 aagtctgtca tcttactagt ttattcctat ttggtaacca gttttattgt tggtgtcatg
    19861 gacattctta cctttagaaa gcaaaatatc attgcactca ttcaagaaaa tggggtcaag
    19921 aaatctgtct tggcaaaagg caagccagct cttcaagcac ttctctttat tctttcgaca
    19981 gctgttatcg gttttggtgc tctctatttt tcagactatc accatctatc actcttgaaa
    20041 agttggggta tcttactggt atctgtcttc gtgatttttg tgattttatt ttacaatacc
    20101 ttgagccatt ttatcttggt ttctcttaga aaactgcctc aaacctacta taacaaacta
    20161 aacagtttta aaattcgtca attttcaaaa caagctgata gtaattcggt cacgttggct
    20221 gtcttatcct tgaccttgac actggctctc agcttactag tttttagtgg tagtgcctat
    20281 acgactatga accgagagct gaacaaatac tcaccttatg acgtatctgt caatctttat
    20341 cgtggtcaag agttccagtt ttctcaggaa tctgtcaaag acagattgaa agcagatgga
    20401 tttgacttta acctcatcaa agaggagtac agctatccta tctattctag tgatttaacc
    20461 tataaagatt tgattgatac tagcaatctt tgggcgcatg ataaggaact tcctgaatca
    20521 aaagtaccga ttttaggaat ttctgcctac aaccatctcc gcaaactgca agggaaaaaa
    20581 gcggttgact tggcagataa ccaatttctg gtcaatgcta actataaagg aactgccaag
    20641 cagattcagg actttctatt aacgacaaaa accctcatga ttaacggtta ttctcttaat
    20701 cttgcgtctt caaagccact tgaaacagtt tactttttat cgtcagtggg tacaaatgac
    20761 acaggaacct taattgtacc agatacggta gtagttggat tgatggaaga ccacacgacc
    20821 tatgttgcca atttcaaaga aaatattgac aaacggaaag tagaaacatt cttaagtcag
    20881 tggattgaaa aatactactt cactcgtgat ggagcagagt tgaatccgtt cacctatcaa
    20941 acgaaaggaa gaatttttga gatttatctt ggatttatgg gcgtcatcgt ctttgtcatg
    21001 atttttgtca gtgttatttt tatcattatt tccctcagta tcttgtcact tcaaacttct
    21061 acaagttctt tggatagtgt caatgattat caaatcttat accttcttgg gaataagaga
    21121 aagcaaaatc gctctattct tttgcaacag attctaagtt atttcttggt tccgctggtt
    21181 atcgcaggtc cgctagcact tgccttgagt acagctcttt tgggctattt tgagaatttc
    21241 gctaatacca gcatttctat tgatatcacc tatctgggag tagcggtttt actctttgtc
    21301 ctttacctgc tagtgactta cagagtaagt tggcaaatta ttgaaaatta agtcaaatac
    21361 cagagttgcc tatccgacaa ttctggtatt gtgttataat gatattaaag tagttcagga
    21421 agtggataca tatgaaacag tttgtcaaat tgatctcgaa aaactcactt ttattgtggt
    21481 ggttgacgat ttttaatcat ctaactttga tgatttatat ttattatagg attcctctgg
    21541 acttttcgac agatttttcc ttacagatgg ttttattgct gattattgct ttaattgcat
    21601 ttagttatat ttgtaatatt gtgacctttc gttatagtga gttgaaactc tggctgctcc
    21661 tgatgatgtt tctcattagc tggcaatcca tatttaatca aggagttacg agcaccctgt
    21721 tgcacttttt tgatattctt catccgctca actatttttt attggtgtat agttctctgt
    21781 ctattctctt tctgggtgag aaaataggag aagaactgtt gagtgtgtcc tttgtgttga
    21841 cactaatcac cgttagttcg tatctgttaa gtccttcaat ttttctcttt ctgtccttgt
    21901 ttgcgtcttt ctttttaaac cttgttccct tgattttatt tattttatat catgaagagt
    21961 tgaaaagtaa actcaagtat cagagacgaa atttgtggat attagcttta atattgcctc
    22021 tttcttattt ctttttgtat atcaatacga cgggctcagg agtgatgaac ctagtctggt
    22081 atttggaaat tcttggtatc ttagcttttt tacacttcaa aacgattgtc agctctcttc
    22141 aaaaaaaggt atcagagttg aaattgtcct atataaaagc tttttcacgc ttgtttttac
    22201 tggttatgtt tttgttagta ggcattttca tcatctttcg tttagactta aacacgagct
    22261 ttttggtctt gaatatcatg ttactattgt tcgggatttg ttcggaagaa ttgattcggc
    22321 tctttcgttc tgctgaaatg ctagattcta gggattatgt taaagttctc tttttaaagc
    22381 gtaaccgtat ggtgaaaaat ctgctggcaa atgaagacac agaacaacag ttctcggaat
    22441 ttcttcacaa tgaaatcctg caaaatgtga tggcaataaa aaatttcaat aaatatagta
    22501 gtaatcaagc ttttggtgaa cagatcaatc tggtgacaga ggagttggtt cagcggattc
    22561 gcgagcggat ggattattat cagccaatga tagaaacaga cgagcagtta gacatccagt
    22621 atcaagggct gattaatcgg attgtcaagc gctatcacgc agaaaatgaa gttgtcacac
    22681 agtttcctgt ccactttagg cttttatctc cttacgataa aattgcctat cgtctggttg
    22741 aggaactgac gaccaatgcc gttaagtacg ctagtggtgg aacgatttct ttgaagattg
    22801 atgtgcatga tgacgctatt tttataattt ctgaaaatga ctgccttcaa atagaaaaat
    22861 ccttaggtta tggcttgaaa aatatgtcta ataaaattag tgttttaggt ggtcagatgc
    22921 agatttttga aaataataag agatttcgtg tagaaattac tctcccgatt gataaggagt
    22981 tgtgttatga aaattttgtt aattgatgat cataaattat ttagccaaag tatcaagatg
    23041 attttagagt tatcggaaaa cattaaaaag gtccagttag tggataattt ttcgactatt
    23101 tcggagattg tttttaatga ctacgacatt attttgattg acatcaacct aacgagtctg
    23161 tatcaagatg atgggctgac cttggcacaa gagattatcg acaatggttg ttctagtaag
    23221 gttgtgattt tgacaggtta cagtaaaaaa atgtatgaat accgagctaa agttatgggg
    23281 gcttatggct ttctggataa aagcatgaac ccagatgagt tggtgaaaaa gctgaaaaag
    23341 atttatctag gtggcaaggt cttttcagat gaagtgatgg tagaggtgct aactccacga
    23401 gaaatcgaga tgctagaact ggttagaaat ggcttgacta ttgatgatat ctgtgaaagg
    23461 atttatgtga gtaaacgtac agtttccaat cacttggcca atatcttttc aaaattggga
    23521 gtgactaaca ggcaggaggc gattcatatc gctgagcagt tgggctattt tccaccagat
    23581 taaaaagttg cagaagatgc agctttttta atttatttac aaaaattgca catattactc
    23641 attctaataa acggtaaatt tgataatcta ttagtaatta aggaggaaat cattatgtct
    23701 atggtatctg aaaaatggtt aagtttattt aataatatcg aagatgatga gcagttagat
    23761 gaatttttaa agactacctc tggagatagt ctacaagatt gggaagtaaa atttcttcag
    23821 tacgagcagt ggggaaaaga ttatattgag cgagagttag gaacaatctt atatgatgaa
    23881 tataaccctc aggaaaaact cagagtaagt attcattggc tagatttatt taaaccaatt
    23941 tgctttaagt acttagagcg attaactagc tttttaaata aaacgcaatg tataactaat
    24001 acaaatgaat ttattctaga gattgaatca gtattttttg aaatttgtat gaatatgagc
    24061 tacagaacgg ttgtcttaga gattaatgat ttaaggagag cgtctcgttt aaaaggtgaa
    24121 gatagtaaaa atagatacaa ttattttatc aatactttat taaaggatag agattatata
    24181 ttggagtttt ataaaaagta tcccgtcttg tttgagttat tagataaaaa gatctctaac
    24241 gtcttagact atattgaaca aattattctc cattttgaag agaatctaat tgacctagaa
    24301 agttatttta attataagaa tttaaaatta tcgagtattg attttaatgc cggtgatact
    24361 cactctaatg gtaagagtgt ttgtattctg aagttaaata ctaagaaaaa gctagtttac
    24421 aaaccaagaa atatgtttat tgatgttaat ttaaacttat tctctaaaga atttgctcat
    24481 cgttttggac tttcagaatt attattcgtc cctaaaacac tgagtaaaga ttcttatagc
    24541 tttgtagagt ttatagaaga gaaagaatgc aattcacttc aggaggtaga agtttattat
    24601 accaatatgg gaaaactttt agcattttta catatttttg gtgctaaaga ttatcatggt
    24661 gaaaacattt tagcttgtca agaacatcct tatcttattg ataatgagac gatattgcat
    24721 ttcagtgagc ctgtaaatat cacttcaaat gcacaaaata tttataattt tgtaactaac
    24781 tcagtttata gtgttggaat attaccaatg aatctttatt cagcaaataa tgacaaagga
    24841 atggaaattg gagcattaaa ttcaggtgaa aggcgagaat caccttattt atcccatcaa
    24901 ctggctaatg ttgggactga tgaaattaga attgaaaaag tatttaaaat agtcggggat
    24961 ttccctagca cagtaagata taaaggaaaa aacgtatcgt gttctagcta cctcaacgag
    25021 gttcaaagag gatttgaaac tatttacaaa attgttttac aaaatagaaa tatagtttct
    25081 aggatgatca ttaaatattt tgaaaattgt gagacgagat atatttatcg aaataccaat
    25141 atttatgtac aatttcttga aacaagccat cacccagaat tgttaaaaaa taaatatgat
    25201 tttgaaatgt atttgcttcg tttatttgaa tatggtgatg ttgctaatct ttttgataat
    25261 gttatgatga aagatgaggt ttgtcagctt agaaaaggtg atattccaat attttatgcg
    25321 aatacaagta gcaatgaaat ttataatggg ctaggtcgat atatttgtgc tttagacgga
    25381 catagtatcg ctaataaggt tttaaataga ataactagtt tatcagatga taatttactc
    25441 agacaaaaac gaattataaa tatggctttt atgggaagcg agttattttc aaagaaattt
    25501 agagtatctg aagaacacat gaatactgaa actattactt caaaaataat caatcggatt
    25561 tcatcagcta aatttgaatt taataatgag actagttggt tagcgatggt ggctatgaat
    25621 aaaagctatg agatatatcc aatggattgt agtctataca gtggaacttc tggtatgatt
    25681 ttggggataa caagcataga tgatactaga ttacggacgc ttttgcctgg ggttatcaat
    25741 tataccaata actatataaa agaattacaa gggaatttcc ctgtacacca attaggtgct
    25801 tttactggtg tatatggata cttatataca ttgtgtgtgt tgagagaaga aggtactcca
    25861 tttgttgaag atatcgaaga gattatatat gaaacattgt catcaacatt tagacaacta
    25921 cgaaatattg acaatttaga tataataggt ggtttagcag gaattttagg agtactgata
    25981 aaaatccaga aaacaatgct cgatagttct cgggtaactg agttgactca gaaattgtct
    26041 gaaggtgtag ttcaaaaaat actagaaaaa tataaaaaag atggattttg gattgaaaat
    26101 gatcctggat atgctcatgg taattatggc attattacgc aactttatag atattcttta
    26161 tctaacacat gcaaatttga tgcaaaaact tccattattt cttgtataaa agaatatctt
    26221 gacaaagagc gttcgttact atgtggaaaa aatggctttc ctttaagaaa taatgccaag
    26281 tattattcat ggtataatgg tattgtggga atagttaatg ctaagaacta tttagaaact
    26341 aatgaatttc ctgacaaatt tttaaagacc gaagttcaag attattccat taaaatttta
    26401 aatcaagatt ctactttaga taattcaatc tgtcatggaa gtatcgggaa cctagtcatt
    26461 ttagattcta ttttaggcta ttctgttgat atagaaaata gaatagctac tgaaagtagc
    26521 tcatatcttt tggataaaga aacttatgaa tgtgatgatt gggggatttt gacaggagaa
    26581 atgggaatat tgatggctaa tgatagaaaa agtaggacta gattaaatga tatactactt
    26641 ttaaattaat gggggttaga tatgaaaaga aacatcccgt ttatcgaaca acaccaaaaa
    26701 acagagtgtg gattatgctg tgttgcgatg gtgtcgaatt tttataatca cgaaatttcc
    26761 gttaaagatc tgagaaatct aaaagaaaca gggagggatg gaactagttt tcaaaattta
    26821 attgaactgt tagaaaatat gggatttaaa gtgaaatcat tccgttttcc aaaagataga
    26881 ccagatgtat ataaacagat aaaagttcca gccattgcat tgtgggagag taagcatttt
    26941 gttgttgtag aaaaagtaac ttctaaattt gtttgggtaa ttgatcctga actcggaaaa
    27001 ttaagatatg atttaaatga gttctcagcc ggtttctcag aattcttaat tagtatttct
    27061 agcagtgata gagtaataaa acaaaaatca aaagagaatt acggagagat ttatgcgaaa
    27121 ctttggcaat cttggcatta ttttgtacct ctgttatttc taacttttgt aagttatgcg
    27181 gttagcttta ttttgcctat atggacgcaa cagctattaa atcaagcaac aggtgggaat
    27241 cagtttaatc cagcaatttt agcgctcaat tttattattt ttacattact atactttatt
    27301 ataatgctcg gtcagagata tctttctatt aatctgacaa acgatataga taaaagactg
    27361 aataatagtg taattggtcg tttgtttcaa ttaccatata aatttttctc tactagaagt
    27421 agtggtgatt taatttattc tataaatggt ttgggtagaa ttcggcaatt atttacaaat
    27481 caggttgtac taggaatatt agatattggt tttgtaattt gtattttgtt ttactttcta
    27541 tatattgatt ttttcgtgac gattatcgct cttatgttag tggtaataaa tttgttgttg
    27601 cttctattga ctagaaagaa tttggaacaa aaaagtaaat cttttgtgat agctcagaat
    27661 gatctccaaa ataaacaaat cgaaatgatt tattctatga tgggaataaa aatggaagga
    27721 tttgaagttc gaacgtttaa acaatggaaa ggttatttag ataagtatct ttatagatat
    27781 agagccagtg aattgttctc aagtgttgtt aattcgttat tttcaattat cacttttata
    27841 tctccattta tcctattatt tattatgttg ttgccagata atcatttagg taataagtta
    27901 ggtggaattt ttgcagtata ttctttatca tctctattat ttggtaagat taatagtatt
    27961 tttgatacga ttgtagcatt ctacaatagc aaaacatttt tatctcggat tttagagatt
    28021 ttaggtgaag aaactgaaat aaatggtgta gtgaaacacg acttaaatgg ggaaatcgca
    28081 cttaaaaatg tttcattttc atatactaga gatagtaaaa aagtactctc taatgtgtct
    28141 attgaaataa agaaggggga aaaggtagca attgttggct cttctggatc aggtaaaagt
    28201 accctttcca aattattgat aggtttattt ccagcatcct caggtagtat tttatttgat
    28261 gacttagatt ataatttgtt ggataaacag tatcttcgtc aacaaattgg cattgtccca
    28321 caagacatga ctttatttaa taaaaccata catgagaata ttgctggaga catctcagtc
    28381 tcagaggaag aaatgacaaa aatttgtaag ttagttaata tccatgatga aattatggaa
    28441 atgcccatgg ggtataatac tttagtttca gaaatgggaa tgaatctgtc aggagggcaa
    28501 cgtcagagaa ttattttagc aagagcgcta gttaagaaac ctaaaataat acttttagat
    28561 gaagccacaa gttatctaga taatgttaat gaaaacgaga ttatgcagaa atttaaagaa
    28621 caaaatatca caattattgt tattgcacat cgactttcta ccattatcga ttctaaccag
    28681 atttttgtaa tggataaagg agaaattgta gaacaaggaa gtcatacaga actattgaat
    28741 atgaaaaatg gtttgtataa aaaactttat cagacggatt actaattttg taagttatat
    28801 tggccacctt cgggtggcat ttttacttct gtgatacttt tttcaagatt tatctgctat
    28861 tcttgaccta gtttttatag aaagaaggtc taagatgtta aataaagtca aaactaaagc
    28921 cttaattagt gttggagcag tggctgcaac tagctttatt ctcatgatgg gatatactgc
    28981 tggtcaacac tcgactgcta aacaaagtcg taaagagatt gaattggctg cagctaaact
    29041 tgtagaggat aaacaagcag aagataaagc cagcattttg tcatcggata ctgtaaaaga
    29101 atttttgacg cagtactata cgaaagaaaa gctcggagaa aataatacac gtattcaacc
    29161 ttatatgact gaatcggctt attctcaaga attgtcaagt caaaatgatg ccatgaacca
    29221 agtgtataag gattatattt tagattatca ttttgaaaat gctgatatct ttgtcaatca
    29281 gactacgaat caagccattg ccatggtctc ttataatgta acctatgtat ctgatttaaa
    29341 gaatgccaac caatcaaaga ccaatcagac agaaaccaga acggttaagt tgtcttattc
    29401 gaaactacca tgtgagttat tggtcaatca agtacaggtt tggaaatctg ggttagatga
    29461 tttggataag gccactccta aaactttaga agaatcatca tcaatatcat cactgccaaa
    29521 tactacgaca aaatgatgat attgcatgga aatagaagaa tgtaagcaaa tttcaattct
    29581 tgatgtagcc aatcgtttag gtatctcctt taaacaagtt tctagccgtg tctatgaaca
    29641 tcctgaacac gattcatttc ggattttttc aactaccaat acttttaaat ggttttcaag
    29701 agatattcaa ggtgatgtca ttgattttgt tcgacttgtt aagggaattt cctttaaaga
    29761 agctctagcc tttctttctg aagaaccttt tcaaaacgaa gctgttcaag aaaaaagaga
    29821 gagaccattt tattatcctt taaagagagt agaagattct aactgcagtc tggctagata
    29881 ttatttaaca gaatgtagag gaatttcaga agaaatcgtt caaaagatga ttcaacaagg
    29941 tttgatagca caagctagct ggaaaacaaa tgaaactgtt gaacctgtta ttgtttttaa
    30001 aagctttgat catcgtcaca agctgcaggc agcaagtctc taagggattt ataagaatca
    30061 ctctcttcct agagagaggt taaaaacgat tctaaaagga agccatggac atgttggaat
    30121 atcctttgat attggtaaac ctaatagact ggtcttttgt gaatcgttca tcgacttaat
    30181 gagctattac gaacttcata aacaaagtct atctgatgtt cgtttggtat ctatggaagg
    30241 attaaaaagg tctgttgttg cttatcaaat tttacgactg atagctgaga atatcagtgc
    30301 taatattgtt gagaaaaaat tgaagagcct ggggaatcaa ctggaattgg aaaggggcag
    30361 gtatgaaaag atggtagtca ggctagataa atttataaat cgcttaaata caggactttc
    30421 aaaaggagat gggatagatt ttcaaaaata ggaatctagc caataattat atacaatgtg
    30481 tatcttttgt aaaatatatt tgaaatttag atttaatcat gttacaatta acattgaaat
    30541 caaatagaaa aggaagatgc aaacgtgggt acactattag caacaagatt aaaaaataga
    30601 cgaaaagaat taaaaatgtc tcagcgagaa ttagctgagg gtatctgtaa acaggggcaa
    30661 attagtcgat tagagagtgg agagttcacc cctggagcgg attttttaca tgcccttgct
    30721 aagaaattaa aagttagtat ggactacttt tttgatgagc aggttgtaga ggaagtcaat
    30781 gagttatcag agtttaagaa gttagcacag acatttatca caaatcgtaa ttatgaatct
    30841 ttaaaatata tatatgaatt ggaaaatgta aaagcccatc gcttatctct agcagataaa
    30901 ttttacatgg aatggataaa gtctcttata gatttttatt tttatggaca gaaagaagag
    30961 gcaattacac gattagagaa tatgctacct cagttaaatg tatctgattt gaactacctt
    31021 caagtttcaa acactctatt caatttttat tatgatattg aagatttaga acgttttaat
    31081 gagattagag acaagctaga gcatcaagtg aatcagctta atttaaacac aattgaagag
    31141 ttagaactat caattaagtt caattataac gtttgtcgat acctatggtt acagaaaaat
    31201 attgaagaag ctattacgaa aagcacagct acgataaagc aatgtaagga gtacaggaca
    31261 acttatctat tagctgattt gtatttattg atgggaagtg taagtgaaaa tttttcttct
    31321 aaaagttcag taaaagaata ttttgagact gctcattttc tctacaaact tgaggaaaac
    31381 atgtcaatgg ctttgaaagt cgaacattat tttgcagata taacagaata aggaatacgg
    31441 tgttctagtg agcatcgttt tttaaatcta atttaaatac aaaaaaagta ttaaataaaa
    31501 aaaaataaaa aaagattata aaaatacttg acaagctaat tttgaagtga taaaataaat
    31561 gcaagaaaac gaaaggagag gtatatgaga agtttgttta ggaaaattgt tgctttgtta
    31621 gtcataggat taatcctatt agggactgct ggaggaactc aagttcataa gatggctaga
    31681 gggattgatc caggtcctgc gaatggtatt tatagatagg agattatagt cacttaaaaa
    31741 tcaaaaaatt ataaaatttt tgttttactt aaatagatat tttatgatgg gcgaagtttt
    31801 tataactagt tcctataagt acagaaacct attttaattt actaatttca aaataatttt
    31861 ttgagatata tgtaattaaa tctaaattaa gctttaaaaa attattttta gcaatttgat
    31921 tttgaaagtg tcatgcagca atatgaaagc gtagaataga ggtgtttcca atgtacaagt
    31981 aagttttgat tccaaataaa gtaatagaaa aggagctata taatgagtag tcaaatgaaa
    32041 gctttcttga atgaacttca aggaaatatg gaagttgttg gagaattttt tgataatcct
    32101 gaaaaggtaa ttagaaaatt tggaattgtc ggaagagaga aggaagcatt gctaatccgt
    32161 gacttaaatg atatggatga ttatgctctt tcaattcaaa atagcgttgc atcgccttct
    32221 ggggcacata gtagcacttg ccattttgtt agacaagatt tacaatccgc ataattgtta
    32281 atatataaaa cataaaattt caattttcaa ttagggataa tagaattcct tactatgata
    32341 tagaaagtga attaattagg aaatcttagt cagaggtttc tgattaattc attttttata
    32401 tattaagagt gatgtgaaat gttcaaattg tgagactact ctcggattgt tgtatagaaa
    32461 tttaaaattt tattgtgagc tttttaagga agagtggccg atatgaaaaa taaatacgat
    32521 gttaaaagaa ttattccgga tgaattatca gaatcactag atatttttct aaaaaattat
    32581 tctgaaactg gattgtcaga ttataatact tatctctttt atggttttat cttgaagtcc
    32641 tataaattgc ctcgagaaaa tagatatagc ataaaattat tggtgaagga attacaaaat
    32701 agaggactga aagttacatt gattatcaac atttattatc acgctttaaa ttgtttggct
    32761 ttaaatgatg gtctaaaaat ttatggagaa gatttcttaa tatgaattac gaaaagtatt
    32821 taaactattt ggactatgaa actgaaatag aagacgcata ccataattta ttattagaat
    32881 ataaaattag tgataatttt agtgatgaac attggttata taatttgccg tctaatatca
    32941 cccaatctaa gggatttaaa atacacctga gcgcctcaat attaaatgct aatttggttg
    33001 ctaaaaaatt ctttgatttt atattttcta gagagaagaa gataaatttc aaaattttgg
    33061 ttagcattaa agaactttct ttgcaaaata cagggcttaa tggttattca caagtcggga
    33121 aattcattac aatttatcca aaagataata aagagtttca acgtttgtta cacaaattag
    33181 aaatattgta taaaggtgta aagggtgtaa acataccatc agatttcaga tttcaactta
    33241 gcgaggttgt atattacaga tatggggagt tcgtaaaaga tagcactttc aaggataaaa
    33301 gagataagaa aatcccttca aatgtgaatg ttccaataag ggattactat attccaagat
    33361 ataacactat tcctgatcaa tatattattt tggaagtgat ttctaaaaat gccaaaggtg
    33421 gagtttataa agtatttaat actcaaaagc gagtttattc tttattaaaa gaagctagtg
    33481 atttatcgtt ggttgatttt acaaatagag attctgtgaa tcgtttaata aatgaaagag
    33541 aaatattagt agaattggaa aaggaggaat ttactccaaa agtttttaac gatttttaca
    33601 taaagaattc gtattttgtg gaatttgagt ttattattgc agataaatta agcgagtata
    33661 atatggttag tggctcgtat gattggtttt taacattaat tgattatatg gagataataa
    33721 actccaaata taatctttcc tatagagatt tatcatttaa taatatactt attgataata
    33781 gaaataatat ttatattata gactttgagc atgccctaag gaaagaaact caaattgaag
    33841 aaaaaaagtt gcctctattt ggaactccag ggttttatga aaccaactta aatttattga
    33901 ataatcaacc agaggatatt atgggattgg ttttgttatt atattggagt cagaatttag
    33961 atgattttaa cgtcttttca aaaatgagtt ttttagaagc gatggagtat gcaatgaatt
    34021 ttaattcgcg tcgcttagac acacttgata aatcagattg gctttatgat atttataaaa
    34081 aagcgttcaa ttataaatat gatacttttt ctgaattaaa aaaagatttt atagaggtat
    34141 taaaataaag gtaggggtgt tatgaattgt ttcttgaaaa tgaataatgt aagtgttcgt
    34201 tatgatgacg taatagcttt aaaagatata actttacaaa taaataaggg agatttcatt
    34261 ggcttattag gttcaaatgg tgcaggtaaa tctacgttaa ttaattctat tgtaggtttt
    34321 caagagattt atttaggaga aatagagtat tgtgataaag atttgatagt tagttctcaa
    34381 ccttttgctc atttaggctt tactcctcaa accacagtaa ttgattttta tactactgtg
    34441 aaggacaatg taatattggg gctgaacctt gctggaaagt ttgggaaaaa tgctgagaag
    34501 ttgtgtcaaa tagccttaga aattgttggg ttagctgata aaaaaaataa tttggtagaa
    34561 acattgtcag gtggacaact gcaacgcgtc cagattgcta gagcaatagc tcataatcca
    34621 gatttttata ttttagatga acctaccgtt ggtttagata ctgaatctgc cgaaaaattt
    34681 ttaatgtatt taaaagataa gagtttggaa ggaaaaacta ttatcatatc ttcacatgac
    34741 ataaatctac tcgaaaagtt ttgtaaaaaa atactttttt tacaaaatgg ctccatatca
    34801 ttttttggtg atatgcgtga ctttgtagat aattcaacta tcaaattaaa tttttcaatg
    34861 cagaatagaa tttctagata tcaaattgaa tttttagaaa attttagatt taaagttcac
    34921 atcgaagata atgatagttt tacaatagaa gtccctatag aagaaaatat cttagatgtt
    34981 atcaatgagg taggaaaagc atgtgaaatt aaaaactttt caacaagtaa attaacctta
    35041 caagaaagtt atttgcaaag aataggagga gaaaaatgaa ggctgatcaa ttaaggcaca
    35101 aatcggactt aggtttaaga ggtctagcga ttattgctaa aaatgagatt attgcttttt
    35161 ttagaagtaa aggtttaatt atttctcagt ttctacaacc aatcttatat gttgttttta
    35221 taataatagg attaaattct tcgataaaga acattcagtt taatgatata aaaacctctt
    35281 atgcagaata tacaatcatt ggtgttatag ctttattgat aatcgggcag atgactcaag
    35341 ttatttatag ggtgacaata gataaaaaat atgggctact tgctcttaag ttatgcagtg
    35401 gagttcgtcc tttatattat attttaggga tgagtatcta ttctatatta gggttgatag
    35461 ttcaagaaat tattatatat ataattacgt tagcgtttga gataaatatc gcaatggata
    35521 gattttttta tacagttttg ttatctattg ttgttttatt attttgggac tcccttgcaa
    35581 ttttacttac aatgtttatc aatgattaca gaagacgtga tattgtaata cgttttgtac
    35641 tgacaccgct tggttttaca gctcctgttt tctacttaat agattctgct cctagtattg
    35701 tgagatggat tggtcagtta aatcccttaa cttatcaatt aactattttg agaaactttt
    35761 attttaaaaa ttcaacaact ttggaattag ttttcttatt gttaacatca ttacttgtcc
    35821 ttatatctgt atcttttatt ataccaaaga taaaattgat actgatagaa agataaaagt
    35881 tgggtcatcc aacttttttg ttgtctcccg aaaaccacta gctatgctag tggttccata
    35941 gagcttttag cgtggtaaca aaaagaacct cctaaaatga taagatagaa gtggtttctc
    36001 cgccactaca acatatcata caggaggtac ctcatgagag aggataatca aagtttatca
    36061 cataccacat ggaattgtaa atatcatatt gtttttgcac ccaaatatcg tcgtcaaatc
    36121 atttatggca gatacaaagc tagtatcgga agaatcatac gtgacttatg tgagcgtaag
    36181 ggtgtaataa tccatgaagc gaatgcttgt tcagaccata ttcacatgct tatcagtatt
    36241 cctccgaaac ttagtgtttt gtcctttatg ggctatttaa agggcaagag cagtttgatg
    36301 atttttgata agcatgcgaa tttaaaatac aaatatggca atcgcaagtt ttggtgtaga
    36361 ggctattatg tagatacggt aggccgtaat cagaaagtga tagctgaata tattcagaat
    36421 caattacaag aagacagagt agcagaccag ctcacgttat tcgagtcagt agatccgttt
    36481 actggcgaaa taaataagag gaagtaacta aggtgcttta gcacctgctc gggaaagtgg
    36541 tgcgcgagga agctatttcg gtgggccttt ggccctggcc ggtagaagcg gcttatagcc
    36601 gcagaacaaa ccaccagttc acactggtgg ttttgattta aaaaacttga tacataaaaa
    36661 taaaagtcta tataaaggat ggtaaaattc ctgttgtccg atttggacaa tatcctaaat
    36721 agttacaata tatggtctat actttttctt aggagaaagc tagatgtaca gacgtttgag
    36781 agatttgagg gaggatcatg atctgaccca aaagcaaata gctacaatac tttcgtttac
    36841 aaattcagct tatgccaaaa ttgaacgggg tgagcatgcg ttgacggctg atgtattggt
    36901 taaactctca gatttctatg acgccagtac agactattta ttgggattaa ctgattttcc
    36961 tgataaaatt cgctttagaa aataatctcc tcaatttcat agagtttgaa aatgagtgag
    37021 attttttatt tgccctttga caactgaata gcctaaaatg gtactttcct catttgtgga
    37081 gcagttttgc ttgattcgcc aagataggag cggggacaat caccaataaa atagagcgat
    37141 actctatctg ccatgatgca aatgatatac aatgatactt ctgaacgttc aggctgccgt
    37201 cgtaaaagag cagtaagtga gattcttatg atgaccccat cagtcatgcc atggagggag
    37261 aagaaattat tcgaaaggat gataatatgg agataaaata cgtatctgtt gaaaattcgg
    37321 tagctgagtg ggcggataag aaaagcatac tgaaacgatg ggaaggtttg aatctctaca
    37381 ctcttaacag atggatcaaa gaaatgagag aaaataagag attttcttta tacgtcatca
    37441 atcctacaca taagctggtg tttataaatc ttgagggatt cgaatgcttt ttgagatgga
    37501 aacaaaagcg gacaaaataa ggaagtcatg gtataatata gagtagttat ttattctata
    37561 caacaatgat ttatttcttt tcgaggaatt aaattatgta ttatgtaact aaaacaaatt
    37621 caaaaggaca acccttgtat caagtggttg aaaaatataa agatccactt actgataagt
    37681 ggagaacagt aactgtcagc tatactagaa atactagtag agcacgaaag caagctgaaa
    37741 gagaggtaat ggataaaata gaaaaactga cctcttccct tgaaagtcag tacaatcctg
    37801 aaatgattac aacttttgga gagttaaaag agagttggtt tcaaacttgg tgcgtatctg
    37861 tcaagcccca gacaataaaa agggaagagt tggtgataga acggcttggt aaaattatcg
    37921 gtgatgaatt tttactcgat cgaattacac cactactgat gaaaaattgt cttaataaat
    37981 atctggataa atacgacgct tcaccttcaa caatgacaca tataaaaagt acgtgtaaca
    38041 agatatttaa tcacggtgtg ctatacaatg tcattaagta ctctccaatg accgctgtta
    38101 aaatagatgt gcctctggag aaaaagagag aagcaagaaa aaggcttgat gctaaatttc
    38161 ttgaaattca tgaattgcaa gccttttttg atgttttagg gcagtgtaga aatgctagct
    38221 attatgacct tgctattgta ttattactga cagggattcg gattggagag gctgcttttt
    38281 taccatcaga tgttgatttt gataagggga ttttacatat tgataaggct ctccaatatc
    38341 atgatttaaa agttgatgaa ttttattttg atacgactaa gaccgtcaat gctgatagag
    38401 aggtagccct cccaatagca gcgagtgaag caatccagag agctataaaa agaaatcagg
    38461 aatttgaagc ctatatggaa caaaatccta gtcctgcttt caaaaagtgt gatagtgtat
    38521 ttcaaactga gtatggttct ccgataactt ctcactcatt tcgtcaagtt ttgaagaggg
    38581 ttgaggagaa gttgttaaaa aattgtcaga aggattatgg ttttaaatgg gtcaagcatg
    38641 tgacccctca ttctttcaga catatgcaca ttagttatct tcaaagtaat gaaatgcaca
    38701 tagctgtaaa ggatattatg actagagttg gtcatgcgaa ttttgaaacc acgatgggct
    38761 acacccataa catcagtcgt tcacaagaaa atactgtaac tgctttaaat caatttgtag
    38821 aaaagcacaa ttttcacttt aaagaattga agagttacac ctgtaaatat tcgagaatga
    38881 ttgaacaatt cattgaaact tgtgatgata acaataaagt agagttaagt gttgatgaat
    38941 ttaaagactt attacacctt ggttcacgtt actcacccaa acatattgtt tcaaatttac
    39001 tgttaaaaat caaaaaagat attgtcaaat atcacccaca gtttgatata aagattgtga
    39061 aattaagcgg gaatcaaatc aaaggttttt ccatttcgtg gtagttttgg tgttcgcttg
    39121 gtgtttagac gatagtaaaa taaatgaggg gtgctaaacc cttgctacga aaggaaaaaa
    39181 atgcaatggc tactattcaa tggtttcctg gtcacatgtc taaagctcgt cgacaggtgc
    39241 aggagaattt aaaatttgtt gattttgtga cgattttagt agatgcacgc ttgcctctat
    39301 ctagtcaaaa tcctatgttg accaagattg ttggtgataa accaaaactc ttgattttaa
    39361 acaaggccga cttggctgat ccagcaatga ccaaggaatg gcgtcagtat tttgaatcac
    39421 aaggaatcca gacgctagct atcaactcca aagagcaagt gactgtaaaa gttgtaacag
    39481 atgcggccaa gaagctcatg gctgataaga ttgctcgcca gaaagaacgt gggattcaga
    39541 ttgaaacctt gcgtaccatg attatcggga ttccaaacgc tggtaaatca actctgatga
    39601 accgtttggc tggtaaaaag attgctgttg ttggaaacaa gccaggggtc acaaaaggtc
    39661 aacaatggct taaaaccaat aaagacctgg aaatcttgga tacaccgggg attctctggc
    39721 ctaagtttga ggatgaaact gttgcactta agttggcatt gactggagct atcaaagacc
    39781 agttgcttcc tatggatgag gttaccattt ttggtatcaa ttatttcaaa gaacattatc
    39841 cagaaaagct ggctgaacgc ttcaaacaaa tgaaaattga agaagaagcg cctgtgatta
    39901 ttatggatat gacccgcgcc ctcggtttcc gtgatgacta tgaccgtttt tacagtctct
    39961 tcgtgaagga agtccgtgat ggcaaactcg gtaactatac cttagataca ttggaagacc
    40021 tcgatggcaa cgattaaaga aatcaaagaa ctccttgtga cagtcaagga gttagaaagc
    40081 cctatttttt tagagcttga aaaggataat cgctcaggag ttcaaaagga aatcagcaag
    40141 cgtaaaagag ccattcaagc tgaattagat gaaaatttgc gcttggaatc catgctttct
    40201 tatgaaaaag aactttataa gcaaggattg accttaattg caggtattga tgaggttggt
    40261 cgtggtcctc ttgctggtcc tgtagtcgct gcggccgtta ttttacctaa aaattgtaag
    40321 attaaaggtc tcaacgacag caagaaaatt cctaaaaaga aacatctgga gattttccaa
    40381 gccgttcaag accaagcctt gtcgattgga attggtatca tagataatca ggtcatcgac
    40441 caagtcaata tctatgaagc aaccaaacta gccatgcaag aagcaatctc ccagctcagc
    40501 cctcaaccag agcacctttt gattgatgcc atgaaactgg acttgcccat ttcacaaacc
    40561 tccattatca aaggagatgc caactccctc tctatcgcag cagcatctat agtagccaag
    40621 gtaacacgtg atgaattgat gaaggaatac gatcagcagt tccctggcta tgatttcgct
    40681 actaatgcag gatatggcac agctaaacat ctggaaggcc tcacaaaact aggagctacc
    40741 ccaattcacc gaaccagctt tgaacccgtt aaatcactgg ttttaggtaa aaaagaaagt
    40801 taattgaaag gaaataccat ggaggaacag tcggaaatag tccgttctaa gaaagaattc
    40861 gcctttgcat ctagcactat actatcccaa gttggtcgag gaatcattgt cggcctcatc
    40921 gttggaatta tcgtcggatc ctttcgtttc ttaattgaaa agggcttcca cctgatacaa
    40981 ggagtttatc aagatcaagg gtacttagtg cgcaatcttt ttgtactggt tttgttttat
    41041 atactcatct gttggctcag tgccaaacta acacggtcag aaaaagatat taaaggctca
    41101 ggaattcctc aagtcgaagc cgaactgaaa ggcctcatgt ccctcaactg gtggggcatt
    41161 ctttggaaaa aatatgtgct aggtattctt gctattgcca gtggactcat gctgggtcga
    41221 gagggaccca gcattcaact tggagcagtt ggtggtaaag gaattgccaa gtggctcaaa
    41281 tccagtccag tagaggaacg ttccttgatt gccagtggag ctgcagcagg tttagccgca
    41341 gcctttaatg ctcctattgc agcacttctc tttgttgtag aagaagtcta tcaccatttt
    41401 tcgcgctttt tctgggtctc aactctagca gccagcatcg tagcaaactt tgtgtctcta
    41461 ctcatgtttg gtttgacacc agtattggat atgccagata acattcctcc catgacccta
    41521 gatcagtatt ggatatatct cgtcatggga attttccttg gatttttagg ttttctctat
    41581 gagaaagctg tattaaacgt tggaagagtt tatgacttga ttggtcaaaa aatccatttg
    41641 gatagggctt attatcccat cttggctttt atccttatca taccagtcgg aatcttctta
    41701 cctcaaatca ttggtggcgg aaatcagctt gtcctttctt taactgaaca aaattttagt
    41761 ttccaagttt tattagctta ctttttgatc cgctttattt ggagtatgat tagctatgga
    41821 agtggactgc caggaggaat tttcctcccc attttagctc ttggttcttt gcttggtgcc
    41881 ttagttggtg ttatctgtgt caatcttgga cttgtcagtc aagagcaatt ccctatattt
    41941 gtcattctag gaatgagtgg ctattttgga gccatatcaa aagctccctt aaccgctatg
    42001 atcctcgtaa ctgagatggt aggagatatt cgcaacctca tgccacttgg tcttgtcact
    42061 cttgtttctt atattatcat ggatttgctc aaaggtacgc cagtctatga agccatgctg
    42121 gaaaaaatgc ttccagaaga agtatctagc gaaggagaag ttacacttat cgaaatacca
    42181 gtttctgata aaattgctgg gaaacaagtt catgaactca acttaccaca caacgtcctc
    42241 atcacaactc aagtccataa tggcaagagc caaacagtta acggctcaac cagaatgtat
    42301 ctgggtgata tgattcacct ggttattcca aaaagtgaaa ttggaaaagt caaagatttg
    42361 ttgttgtagt atgagcattt acataacata aattatgtaa atgctcagct tgatttattt
    42421 agaaaaccga ttctcagaaa tgagatcggt tattttttac tgatgaggaa ttttacatat
    42481 aaataattga actttattaa aaataagact ataattaatt aagttagaaa tgataaagca
    42541 taaagctaga aaggagttta ctgtatcaaa tctgtacagt aagattaaaa tcatgaaaaa
    42601 gaaaacaata gtaattatag tgaaatgaaa tagaaatagg ataaaacaaa caggacaatc
    42661 aaatcaattt ctagcaatgt tttagaagtc cagatgtact attctagttt caatctatta
    42721 tacaatgtgt tttgtatctc atagctcctt atatagctct tcagttatgt agtattaaca
    42781 gaagtttagt gggtgagatt ttcattattt tccttattct gttttgtttg taggtctaag
    42841 tctttttatc actttgaaaa actcctataa catctttctg aaaaactata attttcttga
    42901 aaaatataca agtctatgct atactactag tatacttact tatggagaaa atacatgaaa
    42961 cgtgagattt tactggaacg aatcgacaaa ctaaaacaac tcatgccctg gtatgttctg
    43021 gaatactacc aatctaagct ggctgtgccc tacagtttta caaccctgta cgaatacctt
    43081 aaggaatatg accgattttt cagctgggtt ttggagtctg gtatttcaaa cgctgataaa
    43141 atatccgata ttcctttatc agttttggaa aatatgtcta agaaagacat ggaatccttt
    43201 atcctttatc tacgtgaacg tcccttgctg aatgctaata caacaaaaca aggtgtttca
    43261 cagacaacta tcaatcgaac cttatcagca ctttctagtc tttacaaata tctaaccgag
    43321 gaggttgaaa acgatcaggg ggaaccttat ttctatcgta atgtaatgaa aaaagtttca
    43381 accaagaaaa agaaagaaac ccttgctgcc agagctgaaa atatcaagca aaaactcttt
    43441 ctaggtgatg aaacagaagg ttttctaact tatatcgatc aagagcaccc acaacagctt
    43501 tcaaatcgag ctctctcatc attcaacaaa aataaagaac gagatttagc cattattgcc
    43561 cttctcttgg catctggtgt tcgcttatct gaagctgtta atctagatct aagagatctc
    43621 aatctaaaaa tgatggttat tgatgttact cgaaaaggtg gcaaacgtga ctcagtcaat
    43681 gtcgctgctt ttgctaaacc ttatttagag aattatctgg ccattcggaa tcaacgctat
    43741 aaaacggaaa aaacagatac agcccttttt ttaactctct acagaggtgt tcctaatcgt
    43801 atcgatgctt ctagcgttga gaaaatggtt gctaaatact cagaggattt taaagtacgt
    43861 gtaacacccc ataaactgcg ccatacacta gcaactaggc tctatgatgc gactaaatca
    43921 caagttttag tcagtcacca actaggacat gccagcacac aagtcactga cctctatacc
    43981 catattgtta atgatgaaca aaagaatgct ctggatagtt tataatttta cgtattttaa
    44041 attatgtaaa taaatatcaa aaaaag
//
LOCUS       DAVDHC010000017        40389 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVDHC010000017 DAVDHC010000000
VERSION     DAVDHC010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40389
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.017"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            143..508
                     /locus_tag="VUR43_001252"
     CDS             143..508
                     /locus_tag="VUR43_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET5412939.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCCMKLK"
     gene            584..1525
                     /locus_tag="VUR43_001253"
     CDS             584..1525
                     /locus_tag="VUR43_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET5412940.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDHKIASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            1473..2489
                     /locus_tag="VUR43_001254"
     CDS             1473..2489
                     /locus_tag="VUR43_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET5412941.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEVGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            2491..2817
                     /gene="comGC"
                     /locus_tag="VUR43_001255"
     CDS             2491..2817
                     /gene="comGC"
                     /locus_tag="VUR43_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET5412942.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQADGRITEEQAKAYKEYNDKNGGA
                     NRKVND"
     gene            2810..3214
                     /locus_tag="VUR43_001256"
     CDS             2810..3214
                     /locus_tag="VUR43_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET5412943.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFSAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLPVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            3219..3479
                     /locus_tag="VUR43_001257"
     CDS             3219..3479
                     /locus_tag="VUR43_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412944.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            3442..3903
                     /locus_tag="VUR43_001258"
     CDS             3442..3903
                     /locus_tag="VUR43_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET5412945.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS"
     gene            3881..4294
                     /locus_tag="VUR43_001259"
     CDS             3881..4294
                     /locus_tag="VUR43_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET5412946.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQFFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            4431..5025
                     /locus_tag="VUR43_001260"
                     /pseudo
     CDS             4431..5025
                     /locus_tag="VUR43_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            5086..6039
                     /locus_tag="VUR43_001261"
     CDS             5086..6039
                     /locus_tag="VUR43_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5412947.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKENNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            6090..7280
                     /locus_tag="VUR43_001262"
     CDS             6090..7280
                     /locus_tag="VUR43_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET5412948.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            7429..7800
                     /gene="rnpA"
                     /locus_tag="VUR43_001263"
     CDS             7429..7800
                     /gene="rnpA"
                     /locus_tag="VUR43_001263"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET5412949.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNRFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            7775..8599
                     /locus_tag="VUR43_001264"
     CDS             7775..8599
                     /locus_tag="VUR43_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET5412950.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            8618..9604
                     /locus_tag="VUR43_001265"
     CDS             8618..9604
                     /locus_tag="VUR43_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET5412951.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            9655..10278
                     /locus_tag="VUR43_001266"
     CDS             9655..10278
                     /locus_tag="VUR43_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET5412952.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKVFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            10409..11866
                     /locus_tag="VUR43_001267"
     CDS             10409..11866
                     /locus_tag="VUR43_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET5412953.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIVAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            11889..12170
                     /locus_tag="VUR43_001268"
     CDS             11889..12170
                     /locus_tag="VUR43_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5412954.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            12247..12732
                     /locus_tag="VUR43_001269"
     CDS             12247..12732
                     /locus_tag="VUR43_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5412955.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            12749..13414
                     /locus_tag="VUR43_001270"
     CDS             12749..13414
                     /locus_tag="VUR43_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET5412956.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGIDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            13418..14281
                     /locus_tag="VUR43_001271"
     CDS             13418..14281
                     /locus_tag="VUR43_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET5412957.1"
                     /translation="MVRPIGIYEKATPTHCTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            14283..14987
                     /locus_tag="VUR43_001272"
     CDS             14283..14987
                     /locus_tag="VUR43_001272"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET5412958.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKTWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            15166..16839
                     /locus_tag="VUR43_001273"
     CDS             15166..16839
                     /locus_tag="VUR43_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET5412959.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTLSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFLNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            16951..18042
                     /gene="ulaG"
                     /locus_tag="VUR43_001274"
     CDS             16951..18042
                     /gene="ulaG"
                     /locus_tag="VUR43_001274"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET5412960.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            18156..20132
                     /gene="tkt"
                     /locus_tag="VUR43_001275"
     CDS             18156..20132
                     /gene="tkt"
                     /locus_tag="VUR43_001275"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET5412961.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            20249..20548
                     /gene="yajC"
                     /locus_tag="VUR43_001276"
     CDS             20249..20548
                     /gene="yajC"
                     /locus_tag="VUR43_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET5412962.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            20594..21022
                     /locus_tag="VUR43_001277"
     CDS             20594..21022
                     /locus_tag="VUR43_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET5412963.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            21024..21434
                     /locus_tag="VUR43_001278"
     CDS             21024..21434
                     /locus_tag="VUR43_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5412964.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            21734..24385
                     /gene="adhE"
                     /locus_tag="VUR43_001279"
                     /gene_synonym="adhC"
     CDS             21734..24385
                     /gene="adhE"
                     /locus_tag="VUR43_001279"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET5412965.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(25371..25679)
                     /locus_tag="VUR43_001280"
     CDS             complement(25371..25679)
                     /locus_tag="VUR43_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5412966.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(25676..25984)
                     /locus_tag="VUR43_001281"
     CDS             complement(25676..25984)
                     /locus_tag="VUR43_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5412967.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALEWIGEIR
                     "
     gene            complement(25989..27284)
                     /locus_tag="VUR43_001282"
     CDS             complement(25989..27284)
                     /locus_tag="VUR43_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET5412968.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(27302..28711)
                     /locus_tag="VUR43_001283"
     CDS             complement(27302..28711)
                     /locus_tag="VUR43_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET5412969.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKKEYGNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKRS
                     GRWYRKVSDNNGFEVEIEE"
     gene            28869..29597
                     /locus_tag="VUR43_001284"
     CDS             28869..29597
                     /locus_tag="VUR43_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5412970.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            30057..30251
                     /locus_tag="VUR43_001285"
     CDS             30057..30251
                     /locus_tag="VUR43_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET5412971.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFAT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(30602..31912)
                     /locus_tag="VUR43_001286"
     CDS             complement(30602..31912)
                     /locus_tag="VUR43_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET5412972.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            32149..33021
                     /locus_tag="VUR43_001287"
     CDS             32149..33021
                     /locus_tag="VUR43_001287"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET5412973.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            33152..33981
                     /locus_tag="VUR43_001288"
                     /pseudo
     CDS             33152..33981
                     /locus_tag="VUR43_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            34042..35004
                     /locus_tag="VUR43_001289"
     CDS             34042..35004
                     /locus_tag="VUR43_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET5412974.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSNNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAEASKIAQ
                     FQTKIVCVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQKVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            35181..36188
                     /gene="gap"
                     /locus_tag="VUR43_001290"
     CDS             35181..36188
                     /gene="gap"
                     /locus_tag="VUR43_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET5412975.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(36255..37091)
                     /locus_tag="VUR43_001291"
     CDS             complement(36255..37091)
                     /locus_tag="VUR43_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET5412976.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            37217..39412
                     /locus_tag="VUR43_001292"
     CDS             37217..39412
                     /locus_tag="VUR43_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET5412977.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAVWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            39465..39617
                     /gene="rpmG"
                     /locus_tag="VUR43_001293"
     CDS             39465..39617
                     /gene="rpmG"
                     /locus_tag="VUR43_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET5412978.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            39627..39803
                     /gene="secE"
                     /locus_tag="VUR43_001294"
     CDS             39627..39803
                     /gene="secE"
                     /locus_tag="VUR43_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET5412979.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            39858..>40389
                     /gene="nusG"
                     /locus_tag="VUR43_001295"
     CDS             39858..>40389
                     /gene="nusG"
                     /locus_tag="VUR43_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET5412980.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT        12635 a         7159 c         8586 g        12009 t
ORIGIN      
        1 aatatttttg tacataagta aatagaaatt cagtcatcca tcagatggct ggatttttta
       61 tcaaaaaatt aagaaatgag catatttctt tccttgtctg gcggaattgg ttataatata
      121 cggtacaaag gaatgaatga atatgtatcg tgttatagaa atgtacggag attttgaacc
      181 gtggtggttc ttagaaggtt gggaagaaga tattgtagca agtagaaaat ttgaccagta
      241 ttatgatgct ctcaaatact acaaaacttg ctggtttaga ttggaacaag aatcgcctct
      301 ttataaaagt agaagcgact tgatgaccat tttttgggac ccggaagacc aacgctggtg
      361 tgatgaatgt gatgagtatt tacaacaata ccattctttg gctcttttgc aggatgagca
      421 ggttatccca gacgaaaaac tacgctcagg ctatgaaaaa caaaccagtc aggaaaggaa
      481 tcgttcttgc tgtatgaaat taaaatagag aaaagtaact tttttggagt tgcttttttt
      541 atttttctaa ctctttgcga atagtatagg tgaggaggta agtatggttc aagaaattgc
      601 acaagaaatc attcgttcag ctcggaaaaa agggacgcag gatatctatt ttgtccctaa
      661 gttagacgcc tatgagcttc atatgagggt aggagacgag cgctgtaaaa ttggtagcta
      721 tgattttgaa aagtttgcag ccgttatcag tcactttaag tttgtggcgg gtatgaatgt
      781 gggagaaaaa agacgtagtc aactgggttc ctgtgattat gcctatgacc ataagatagc
      841 gtctctacgt ttatctactg taggcgatta tcgggggcat gagagtttgg ttatccgttt
      901 gttgcacgat gaggagcagg acctgcattt ttggtttcag gatattgaag aattaggcaa
      961 gcagtacagg caacggggac tctatctttt tgctggtccg gttgggagtg gtaagacgac
     1021 cttgatgcat gaattgtcca agtcactctt taaaggacag caagttatgt ccatcgaaga
     1081 tcctgtcgaa atcaagcagg acgacatgct tcagttgcag ttgaacgaag caatcggcct
     1141 aacctatgaa aatctaatca aactttcctt gcgtcatcga ccagatctct tgattatcgg
     1201 agaaattcgt gacagcgaga cggcgcgtgc agtggtcaga gctagtttga caggtgcgac
     1261 agtcttttca accattcacg ccaagagtat ccgaggtgtt tatgagcgtc tgctggagtt
     1321 gggtgtgagt gaagaagaat tggcagttgt tctgcaagga gtctgctacc agagattaat
     1381 cgggggagga ggaatcgttg actttgcaag cagagattat caagaacacc aagcagccaa
     1441 gtggaatgag caaattgacc agcttcttaa agatggacat atcacaagtc ttcaggctga
     1501 gacggaaaaa attagctaca gctaagcaaa aaaatatcat caccctattt aacaatctct
     1561 tttctagcgg ttttcatctg gtggagacta tctccttttt agataggagt gctttgttgg
     1621 acaagcagtg tgtgacccag atgcgtgtgg gcttgtctca ggggaaatca ttctcagaaa
     1681 tgatggaaag tttgggatgt tcaagtgcta ttgtcactca gttatcccta gctgaagttc
     1741 atggcaatct ccacctgagt ttgggaaaga tagaagaata tctggacaat ctggctaagg
     1801 tcaagaaaaa attgattgaa gtagcgacct atcccttgat tttgctgggt tttcttctct
     1861 taattatgct ggggctacgg aattacctgc tcccacaact ggatagtagc aatattgcca
     1921 cccaaattat cggtaatctg ccccaaattt ttctaggcat ggtagggctt gtttccgtgc
     1981 ttgccctttt agcactcact ttttataaaa gaagttctaa gatgagtgtc ttttctatct
     2041 tagcacgcct tccctttatt ggaatctttg tgcagaccta cttgacagcc tattatgcac
     2101 gtgaatgggg gaatatgatt tcacagggaa tggagttgac gcagattttt caaatgatgc
     2161 aggaacaagg ttcccagctc tttaaagaag tcggtcaaga tctggctcaa accctgaaaa
     2221 atggccgtga attttctcag acgataggaa cctatccttt ctttaggaag gaattgagtc
     2281 tcatcataga gtatggggaa gttaagtcca agctgggtag tgagttggaa atctatgctg
     2341 aaaaaacttg ggaagccttt tttacccgag tcaaccgcac catgaatttg gtgcagccac
     2401 tggtttttat ctttgtggca ctgattatcg ttttacttta tgcggcaatg ctcatgccca
     2461 tgtatcaaaa tatggaggta aatttttaaa atgaaaaaaa tgatgacatt cttgaaaaaa
     2521 gctaaggtta aagcttttac attggtggag atgttggtgg tcttgctgat tatcagcgtg
     2581 cttttcttgc tctttgtacc taatctgacc aagcaaaaag aagcagtcaa tgacaaagga
     2641 aaagcagctg ttgttaaggt ggtggaaagc caggcagaac tttatagctt agaaaagaat
     2701 gaagatgcta gcctaagaaa gttacaagca gatggacgca tcacggaaga acaggctaaa
     2761 gcttataaag aatacaatga taaaaatgga ggagcaaatc gtaaagtcaa tgattaaggc
     2821 ctttaccatg ctggaaagtc tcttggtttt gggacttgtg agtatccttg ccttgggctt
     2881 gtccggctct gtccagtcca ctttttcagc ggtagaggaa cagattttct ttatggagtt
     2941 tgaagaactc tatcgggaaa cccaaaaacg cagtgtagcc agtcagcaaa agactagtct
     3001 gaacttagat gggcagacgc ttagcaatgg cagtcaaaag ttgccagtcc ctaaaggaat
     3061 tcaggcccca tcaggccaaa gtattacatt tgaccgagct gggggcaatt cgtccctggc
     3121 taaggttgaa tttcagacca gtaaaggagc gattcgctat caattatatc taggaaatgg
     3181 aaaaattaaa cgcattaagg aaacaaaaaa ttagggcagt gattttactg gaagcagtag
     3241 tcgctctagc tatctttgcc agcattgcga ccctcctttt gggacaaatt caaaaaaata
     3301 ggcaagagga agcaaaaatc ttgcaaaagg aagaagtctt gagggtagct aagatggccc
     3361 tgcagacggg gcaaaatcag gtaagcatca acggagttga gattcaggta ttttctagtg
     3421 aaaaaggatt ggaggtctac catggttcag aacagttgtt ggcaatcaaa gagccataag
     3481 gtcaaggctt ttaccttgtt agaatccctg cttgccctca ttgtcatcag tgggggatta
     3541 ctcctttttc aagctatgag tcagctcctc atttcagaag ttcgctacca gcaacaaagc
     3601 gagcaaaagg agtggctctt gtttgtggac caacttgagg tagaattaga ccgttcgcag
     3661 ttcgaaaaag tagaaggcaa tcgcctatac atgaagcaag atggcaagga catcgccatc
     3721 ggtaagtcaa agtcagatga tttccgtaaa acgaatgctc gtggtcgagg ttatcagcct
     3781 atggtttatg gactcaaatc tgtacggatt acagaggaca atcaactggt tcgctttcat
     3841 ttccagttcc aaaaaggctt agaaagggag ttcatctatc gtgtggaaaa agaaaaaagt
     3901 taaggcaggt gttctcctct acgcagtcac catagcagcc atctttagtc ttttgttgca
     3961 attttatttg aaccgacaag tcgcccacta tcaagactat gctttgaata aagaaaaatt
     4021 ggttgctttt gctatggcta aacgaaccaa agataaggtt gagcaagaaa gtggggaaca
     4081 gttttttaat ctaggtcagg taagctatca aaacaagaaa actggcttag tgacgagggt
     4141 tcgtacggat aagagccaat atgagtttct gtttccttca gtcaaaatca aagaagagaa
     4201 aagagataaa aaggaagagg tagcgaccga ttcaagcgaa aaagtggaga agaaaaaatc
     4261 agaagagaag cctgaaaaga aagagaattc atagtcaatt caactataat gcgttgaatc
     4321 cagaatagtc cactgtagtt tctagaaaat tgctggaaat ggatgttaag ctccaattca
     4381 tttgtttata tcttatttca gtttactata ctttgtgcta aattaaagat atgaaacatg
     4441 attttaacca caaagcagaa actttcgatt cccctaaaaa tatcttcctc gcaaacttgg
     4501 tatgtcaagc agccgagaaa cagattgatc ttctatcaga caaagaaatt ttagatttcg
     4561 gtggtggcac gggtctatta gccttgcccc taacccctag ccaagcaggc taagtcagtc
     4621 actcttgtag acatttctga gaaaatgttg gagcaagctc gtttgaaagt ggagcagcaa
     4681 gcaatcaaga atatccagtt tttggagcaa gatttaccga aaaatccctt ggagaaagag
     4741 tttgattgcc ttgctgttag tcgggttctt catcatatgc ctgatttgga tgcggctctc
     4801 tcactgtttc atcaacattt gaaggaagat gggaaactca tcattgctga ttttaccaag
     4861 acagaagcta atcatcatgg atttgattta gctgaactgg aaaacaagct aattgagcat
     4921 ggtttttcat ctgtgcatag tcagattctc tatagtgctg aagacctgtt tcaaggaaat
     4981 cactcagaat tctttttaat agtagcccaa aaatcactcg cctagtcagg gagtgatttt
     5041 tctataagga tggaaaaaag aagggaaatt tggtaagata ggaatatgga ttttgaaaaa
     5101 attgaacaag cttataccta tttactagag aatgtccaag tcatccaaag tgatttggcg
     5161 accaactttt atgacgcctt ggtggagcaa aatagcatct atctggatgg tgaaactgag
     5221 ctaaaccagg tcaaggagaa caatcaaacc cttaagcgtt tagcactacg caaagaagaa
     5281 tggctcaaga cctaccagtt tctcttgatg aaggctgggc aaacagaacc cttgcaggcc
     5341 aatcaccagt ttacaccgga tgctattgct ttgcttttgg tgtttattgt ggaagagttg
     5401 tttaaagagg aggaaattac tatcctcgaa atgggttctg ggatgggaat tctaggcgct
     5461 attttcttga cctcgcttac taaaaaggtg gattacttgg gaatggaagt ggatgatttg
     5521 ctgattgatc tggcagctag catggcagat gtaattggtt tgcaggctgg ctttgtccaa
     5581 ggagatgccg ttcgcccaca aatgctcaaa gaaagcgatg tggtcatcag tgacttgcct
     5641 gtcggctatt atcctgatga tgccgttgcg tcgcgccatc aagttgcttc tagccaagaa
     5701 catacttacg cccatcactt gctcatggaa caagggctta agtacctcaa gtcagacgga
     5761 tacgctattt ttctagctcc gagtgatttg ttgaccagtc ctcaaagtga tttgttaaaa
     5821 gaatggctga aagaagaggc gagtctggtt gctatgatta gtctgcctga aaatctcttt
     5881 gctaatgcca aacaatctaa gactattttt atcttacaga agaaaaatga aatagcagta
     5941 gagccttttg tttatccact tgctagcttg caagatgcaa gtgttttaat gaaatttaaa
     6001 gaaaattttc aaaaatggac tcaaggtact gaaatataaa atagattttg ttataatagt
     6061 tgaaaacgct taaaaagggg tatcatgtta tgacaaaaac aattgcaatc aatgcaggaa
     6121 gttcaagttt gaaatggcaa ttatacttaa tgccagaaga aaaagtattg gcgaaaggtt
     6181 tgattgaacg tatcggtttg aaagattcaa tttcaactgt aaaatttgac ggccgttctg
     6241 aacaacaaat tttggatatt gaaaatcata tacaagccgt taaaatttta ttggatgact
     6301 tgattcgttt cgatattatc aaggcttatg acgagattac aggtgttgga catcgtgttg
     6361 ttgctggtgg agaatatttc aaagaatcaa cagttgttga gggagatgtt ttagaaaaag
     6421 ttgaagagtt gagtttgttg gctcctctac acaacccggc caatgcagca ggtgttcgtg
     6481 ccttcaagga attgttgcca gacattacca gtgtagttgt ttttgatact tccttccaca
     6541 caagtatgcc agagaaagct tatcgctacc ctctaccaac aaaatattac acagaaaaca
     6601 aggttcgtaa atacggtgct catggtacaa gtcaccagtt tgtagcagga gaagctgcaa
     6661 aactcttggg acgtccatta gaagacttga agttaattac ctgtcatatt ggtaacggag
     6721 gctcaattac agctgtgaaa gccggcaaat ctgtagacac ttctatgggg ttcactcctc
     6781 ttggtggtat tatgatggga acgcgtacag gggatattga tccagctatc attccttatt
     6841 taatgcaata tacagaggat tttaacacac cagaagatat cagtcgtgtt cttaaccgtg
     6901 aatcaggtct tttgggagtt tctgctaatt ctagcgatat gcgcgatata gaagcagctg
     6961 tagcagaagg gaatcacgag gctagcttgg cttatgaaat gtatgttgac cgtatccaaa
     7021 aacatatcgg tcagtacctt gcagtgctaa atggagcaga tgccattgtt ttcacagcag
     7081 gtgtcggtga aaatgcagag agtttccgtc gtgatgtaat ctcagggatt tcgtggtttg
     7141 gttgtgatgt tgatgatgaa aagaatgtct ttggcgttac aggagacatc tcaacagagg
     7201 cagctaaaat ccgtgtcttg gttattccaa cagatgaaga attagtcatt gcccgtgacg
     7261 ttgaacgctt gaaaaaataa gtgaaactaa aaaaatattc aatacaagga gttgggaaag
     7321 ttatttttcc agcttctttt tctgatgaaa ttgtccaaaa ccttgctatg attggctttt
     7381 ttgaaaaata tggtataata gtagtaattt aatagatgga gttgagtttt gaagaaaaac
     7441 tttcgtgtaa aaagagagaa agattttaag gcgattttca aggaggggac aagttttgct
     7501 aatcgcaaat ttgtggtcta ccaattagaa aaccagaaaa accgttttcg agtaggtcta
     7561 tcagttagca aaaaactggg gaatgccgtc actagaaatc aaattaagcg acggattcgg
     7621 catattatcc agaatgcaaa agggagtctg gtagaagatg tcgactttgt tgtcattgct
     7681 cgaaaaggag tcgaaacctt gggatacgca gagatggaga aaaatctact ccatgtatta
     7741 aaattatcaa agatttaccg ggaaggaaat gggagtgaaa aagaaactaa agttgactag
     7801 tttgctagga ctgtctctgt taatcatgac agcctgtgcg actaatgggg taactagcga
     7861 tattacagcc gaatcggctg atttttggag taaattggtt tacttctttg cggaaatcat
     7921 tcgcttttta tcgtttgata ttagtatcgg agtggggatt attctcttta cggtcttgat
     7981 tcgtacagtc ctcttgccag tctttcaggt gcaaatggtg gcttctagga aaatgcagga
     8041 agctcagcca cgcattaagg cgcttcgaga acaatatcca ggtcgagata tggaaagcag
     8101 aaccaaacta gagcaggaaa tgcgtaaagt atttaaagaa atgggtgtca gacagtcaga
     8161 ctctctttgg ccgattttga ttcagatgcc ggttattttg gccctgttcc aagccctatc
     8221 aagagttgac tttttaaaga caggtcattt cttatggatt aaccttggta gtgtggatac
     8281 aacccttgtt cttccgattt tagcagcagt attcaccttt ttaagtactt ggttgtccaa
     8341 caaagctttg tctgagcgaa atggcgctac gactgcgatg atgtatggga ttccagtctt
     8401 gatttttatc tttgcagttt atgcgccagg tggagtcgcc ctatactgga cagtgtctaa
     8461 tgcttatcaa gtcttgcaaa cctatttctt gaataatcca ttcaagatta tcgcagagcg
     8521 cgaggccgta gtacaggcac aaaaagattt ggaaaataga aaaagaaaag ccaagaaaaa
     8581 ggctcagaaa acgaaataaa taaggaggaa tctggtagtg gtagtattta caggttcaac
     8641 tgttgaagaa gcaatccaga aaggattgaa agaattagat attccaagaa tgaaggctca
     8701 tatcaaagtc atttctaggg agaaaaaagg ctttcttggt ctatttggta aaaaaccagc
     8761 ccaagtggat attgaagcga ttagtgaaac gactgttgtc aaagcaaatc aacaggtagt
     8821 aaaaggcgtt ccgaaaaaaa tcaatgattt gaacgagcct gtgaagacgg ttagtgaaga
     8881 aaccgttgac cttggtcatg tggttgatgc tattaaaaaa atagaggaag aaggtcaagg
     8941 tatttctgat gaagtcaagg ctgaaatctt aaaacatgaa agacatgcca gcactatctt
     9001 agaagaaact ggtcacattg agattttaaa tgaacttcaa atcgaggaag cgatgaggga
     9061 agaagcaggc gctgatgacc ttgaaactga gcaagaccaa gctgaaagtc aagaactaga
     9121 agacttgggc ttgaaagttg aaacgaactt tgatattgaa caagtagcta cggaagtaat
     9181 ggcttatgtt caaacgatta ttgatgacat ggatgttgag gctacacttt caaatgatta
     9241 taaccgtcgt agcatcaatc tacaaattga caccaacgaa ccaggtcgta ttatcggcta
     9301 ccatggtaaa gtcttgaagg ccttgcaact gttggctcaa aattatcttt acaaccgcta
     9361 ttccagaacc ttctacgtta caatcaatgt caatgattat gtcgaacacc gtgcagaagt
     9421 cttgcagacc tatgcgcaaa aattggcgac tcgtgttttg gaagaagggc gcagtcataa
     9481 aacagatcca atgtcaaata gcgaacgcaa gattatccat cgtattattt cacgtatgga
     9541 tggcgtgact agttactctg aaggtgatga gccaaatcgc tatgttgttg tagatacaga
     9601 ataagtaaaa tcaggtttat cctgattttt tgctagttag aggaggttaa actgatgttg
     9661 aataagataa gagactattt agactttgct ggtttgcagt accgtaatcc tgataaagcg
     9721 ggagcagagc gagagaagat gctggcattc cgccacaaag gacaagaggc ccgaaaggtt
     9781 tttacagaac tggccaaagc ctttcaagca agccatccag aatggcaact ccaacagact
     9841 agccagtgga tgaatcaggc ccagcgtttg agaccacatt tttgggttta tctacagaga
     9901 gacggacaag tgacagaacc tatgatggcc ttacgtttgt atgggacatc tactgacttt
     9961 ggaatttctt tggaagtcag tttcatcgaa cgtaagaagg atgagcaaac actgggcaag
    10021 caggccaaag ttttagacat tccaaccgtt aaagggattt attatctaac ctactctaat
    10081 ggtcaaagtc aacggtggga ggcgaatgaa gaaaagcgtc gtactttacg cgagaaggtg
    10141 agaagtcaag aagttcgaaa agttttagtg aaggtagatg ttcctatgac agaaaattcg
    10201 tctgaagaag aaatcgtaga aggcttattg aagtcttatt ctaaaattct tccctattat
    10261 ctagctacga gaaaataaga taatttgtaa aacatcataa atcatacagt ccaagagtga
    10321 acagtccgct gtgtaattct tggtcttttt gtttgcgctt tcgcattata taataaactt
    10381 acaaaaacaa ttcaaaagga gaacaattat ggaagtcgtt tcaagtgttc taaattggtt
    10441 ttctagcaat attttgcaga atcccgcatt tttcgtaggt ttattggtgt tgataggata
    10501 tgcacttttg aaaaaacctg cccatgacgt tttttcaggg tttgttaaag caacagtagg
    10561 gtatatgttg cttaacgtgg gtgctggtgg tttggttaca acctttcgtc caatcttagc
    10621 agctcttaac tacaaattcc aaattggtgc agcggttatc gacccttact ttggacttgc
    10681 tgcagcaaac aacaaaattg tagcagagtt tccagatttt gttggaactg caactacagc
    10741 tctattgatt ggttttggaa taaatatctt gctcgtagct cttcgaaaga ttacgaaggt
    10801 aagaaccctc tttattactg gtcacatcat ggtacaacaa gctgcaacag tatctcttat
    10861 ggttctattc ttagtaccac aattgcgcaa tgcttacggt acagcagcga ttggtatcat
    10921 ctgtggactt tactgggcag ttagttcaaa tatgactgtt gaggcaactc aacgcttgac
    10981 tggtggtggc ggatttgcga ttggtcacca acagcaattt gcaatctggt ttgtagataa
    11041 agtagcagga cgctttggta agaaagaaga aagtttagac aatcttaaat tacctaagtt
    11101 cctctcaatc ttccacgata cagttgttgc atctgctacc ttgatgctcg tattcttcgg
    11161 agccattctt ttaatcttgg gtccagacat tatgtctaat aaagaagtca tcacttcagg
    11221 aactctattc aatcctgcta aacaagattt ctttatgtac attatccaaa cagcctttac
    11281 cttctcagtt tacttgttcg ttttgatgca aggtgtccga atgttcgtat ctgagttgac
    11341 aaacgccttc caaggtattt caaacaaatt gttgccaggt tcattcccag cggttgacgt
    11401 tgcagcttct tatggatttg gttctccaaa tgctgtcttg tcaggattta cctttggttt
    11461 gattggtcaa ttgattacaa ttgtcttgct catcgtcttt aaaaatccga ttcttattat
    11521 tacaggattt gtaccagtgt tctttgacaa tgcagccatt gcggtctacg ctgataaacg
    11581 cggcggatgg aaagcggctg ttatcctttc ctttatatca ggtgtccttc aagttgctct
    11641 aggagctctt tgtgtggccc ttctcgattt ggcatcttat ggtggctacc atggaaatat
    11701 cgactttgaa ttcccatggc ttggatttgg atatatcttc aaataccttg gtattgttgg
    11761 ttatgtactt gtgtgtctct tcttgcttgt tattcctcaa cttcaatttg ccaaagcaaa
    11821 agataaagag aaatattaca acggtgaagt tcaagaagaa gcttagtatc tagaaaagga
    11881 gaaataaaat ggttaaagta ttagcagcgt gcggaaatgg aatgggttca tcaatggtta
    11941 tcaagatgaa ggttgaaaat gctctccgta agcttaatca aacagatttt acagtcaatt
    12001 catgcagtgt cggtgaagct aaaggtttag cagtaggata tgacatcgta atcgcttctc
    12061 ttcatttgat tcaagaattg gaagggcgaa ctaatgggaa gttaattggg cttgataact
    12121 tgatggatga taaagaaatc accgaaaaac tcagtcaagc actacagtaa aaggttggag
    12181 ggggctggac agaaactgag agttatcgtt tctgtccttc tccctcttta aataaaggag
    12241 gcagatatga atttaaaaca agctttaatt gacaatgact cgatccgact aggtttagag
    12301 gctaacaatt ggaaagaagc agtcaaggta gcagtagatc ccttaattga aagtggggca
    12361 attttgccag agtattacga tgctatcatt gaatcgactg aagagtatgg gccttactat
    12421 atcttgatgc caggtatggc tatgccccac gctagacctg aagcaggtgt gcaaagtgat
    12481 gccttttcat tgattacctt acaaaatcct gttgtatttt cagatgggaa agaggtatct
    12541 gttttgttgg cactagcagc aacaagttca aaaattcaca caagtgtagc cattccacaa
    12601 attattgccc tatttgaatt agaagattct attgcacgtt tacaggcttg ccagactaaa
    12661 gaagatgtct tggctatgat tgaagaatct aaggatagcc cttatctcga aggattggat
    12721 ttggaaagtt agaaagagga ataaagaaat gacaaaaaga atacctaatt tacaagttgc
    12781 attagaccat tcagacttgc aaggagcgat taaagcagct gtttctgttg gtcaggaagt
    12841 agatattatc gaagctggaa ctgtttgctt gcttcaagtt ggaagtgaac tggctgaagt
    12901 cttgcgtagc cttttcccag ataagattat tgtggcagac acaaaatgtg ctgatgctgg
    12961 tggaacagtt gctaaaaata atgcggttcg tggagcagac tggatgactt gtatctgttg
    13021 tgcaaccatc cctactatgg aagcagctct aaaggctatc aagactgaac gaggagaacg
    13081 aggcgaaatc cagatcgagc tttatggcga ttggactttt gaacaagctc agctttggct
    13141 agatgcaggt atctcacaag ctatttatca ccaatctcgt gatgctcttc ttgctggtga
    13201 aacttggggt gaaaaagacc ttaataaggt taaaaaactc attgacatgg gcttccgtgt
    13261 atctgtaaca ggtggtctag atgtagatac tctcaaactc tttgaaggta ttgatgtctt
    13321 tacctttatc gcaggtcgtg gaattacaga ggctgtggat ccagcaggag cagcgcgtgc
    13381 cttcaaggat gaaatcaaac gaatttgggg gtaaatcatg gtacgtccaa ttggaattta
    13441 tgaaaaggca accccaacac actgtacttg gctagaacgt ttaaattttg ccaaggagtt
    13501 aggctttgat tttgtcgaga tgtctattga cgaacgtgac gagcgtttag caagacttga
    13561 ctggagtaag gaagaacgct tggaagttgt caaagcaatc tatgaaactg gtgttcgtat
    13621 tccttctatc tgtttttcag gccatcgtcg ctacccattg ggttcaaaag atccagttct
    13681 agaggaaaaa tctctagaac tcatgaaaaa atgtatcgaa ttagctcaag acttgggagt
    13741 tcgtacgatt caattagctg gttacgatgt ttactatgag gaaaagtcac cccagacacg
    13801 ccaacgtttt atcaaaaatt tgagaaaagc ctgtgactgg gctgaagaag ctcaggtggt
    13861 acttgctatt gaaattatgg atgatccttt catcagtagc atcgaaaaat atttggctat
    13921 agaaaaagag attgactctc ccttcctctt tgtatatcca gatattggta atgtgtctgc
    13981 atggcataat gatatctata gtgagtttta tcttggtcat catgccatcg cagctctcca
    14041 tctcaaggat acttatgcag tgacagaaag ttcaaagggc cagttccgag atgtaccttt
    14101 cgggcaaggt tgtgtcaaat gggaagaagc tttcgatatt ttaaaggaaa ccaattataa
    14161 tggacctttc ctaatcgaaa tgtggtctga aaattgtgaa acagtagaag aaacacgcgc
    14221 agccattcaa gaggcgcaag cttttctcta tccactcatt aagaaagcag gtttgatgta
    14281 agatgaatca agtaatcaat gctatgcgta aacgagtctg tgatgccaat caatcattgc
    14341 caaaacatgg acttgtcaaa tttacctggg ggaatgtatc tgaagttaat cgcgaactcg
    14401 gtgtcattgt tatcaaacca tcaggcgtgg attatgacga attgacacct gaaaacatgg
    14461 tagtgactga tctagatggt aagatcctag aaggggattt aagaccatct tccgacctcc
    14521 caactcatgt gcaattatat aagacttggt cagaaattgg tagtgtggtt cacacccatt
    14581 cgacagaagc tgttggttgg gctcaggcag gtcgtgatat tcctttctac ggaacaaccc
    14641 atgcagatta tttctacggt tcaatccctt gcgcccgtag tttgaccaag gacgaagtag
    14701 aagtggccta tgaaaaagat actggcctgg ttatcgtaga agagtttgaa catcgcggac
    14761 ttaacccggt tgaagtacca ggaattgttg tacgcaatca cggtccattc acctggggca
    14821 aaaatccaga gaatgctgtt tatcactctg tcgtactaga ggaagtatca aagatgaatc
    14881 gctttacaga acaaatcaat ccaagagttg gacctgctcc ccagtacata ctagaaaaac
    14941 actaccaacg taaacatgga ccaaatgctt attatggtca aaagtaagaa cgatgaagga
    15001 ggagaaaaag ataaatttag ctcctctttt tacatttgat ttttattgag agtaaagttg
    15061 gagttgaagt aattttaaaa gattttttag aaatagcgct tgatatatat atggtaaaat
    15121 aaaaagaatt gctgtgatat caatagattt gggggatttt ttaatatggt actggataag
    15181 gcaagttgtg atttgcttca atatttgatg gatcaagaaa cgtccaaaac gattatggcg
    15241 atttcgaaag atttgaaaga gtcaagaagg aaaatttatt atcacattga caaaatcaat
    15301 gctgctctgg gtgacgaggc gcttcacatc attagtattc cacgaattgg tattcactta
    15361 acggaagagc agagagatgc ttgttgtaaa ctattatcgg aagtagattc gtacgattat
    15421 atcatgagtg cgcatgaacg tatgatgata atgttactat ggataggtat ttctaaagaa
    15481 cgtattacta ttgaaaaatt gatagagtta acagaggtat ctaggaatac tgttctcaat
    15541 gatttgaata gtattcgtta tcaactaact ttggaacaat atcaggtgac cttgcaagtg
    15601 agcaagtcac agggatacca ccttcatgcc caccctctta ataaaattca gtatcttcaa
    15661 tcgcttctat atcatatttt tatggaagaa aatgccactt ttgtatctat tttagaagat
    15721 aagatgaaag agaggttaga tgatgagtgt ttgctttctg ttgaaatgaa ccaatttttt
    15781 aaggaacagg ttcctttagt tgaacaagat ttagggaaga aaataaacca tcatgaaata
    15841 acttttatgt tgcaggttct accttatttg ctgttaagct gtcataatgt tgaacagtat
    15901 caagaaagac atcaggatat agagaaagaa ttttctttga taagaaaaag aatagagtat
    15961 caggtgtcta agaaattagg agaacggttg tttcaaaagt ttgaaatttc tttgtcagga
    16021 cttgaagttt ctcttgtagc tgttctcctc ctctcctatc gtaaagattt ggatattcat
    16081 gcagaaagtg atgattttcg gcaattaaaa cttgctttag aagaatttat ctggtatttt
    16141 gaatcacaaa tccgaatgga gattgagaac aaggatgatt tgttacgaaa tttgatgatc
    16201 cactgtaaag ccttgttatt tagaaagact tacggtattt tttctaaaaa tcctctaaca
    16261 aaacaaattc gatccaagta tggagaatta tttttagtca ctagaaaatc tgcggaaatt
    16321 ttagaaggag catggtttat tcggctaaca gacgatgata ttgcctattt gacgattcat
    16381 attggaggat ttttaaagta tacactatcg tctcaaaaaa atatgaaaaa agtttatctc
    16441 gtttgtgatg aaggtgttgc ggtttcgaga cttttgctga aacaatgcaa actttatttt
    16501 ctaaatgagc aaattgacac tgtatttaca acagaacaat ttaagagtgt ggaagatatt
    16561 gcacaagttg atgtagtgat tactactaat gatgatttgg atagcagatt tccgatttta
    16621 agggttaatc ctatccttga agcagaagat attttgaaaa tgctagacta tcttaaacac
    16681 aatatatttc gtaataagag caaaagtttc agtgaaaatc tttctagtct tatttcgtct
    16741 tatattgtag acagcaagtt ggctagtaag ttccaagaag aggttcaaac acttataaat
    16801 caagaaatag tagttcaagc ttttttggaa gatatttgaa ggacagtcca atgatgaaca
    16861 caaacctgtg tttttcttgg tcttttttag tgttttgaag ggtggtatac taatctcaaa
    16921 gataacaatt atatccaaag gaggcaacat atgccaaacg tcaaagaaat tacaagagag
    16981 tcatggattt tagccacttt cccagagtgg ggaacatggt tgaacgaaga aatcgaagaa
    17041 gaagtcgtac ctgaaggcaa ctttgccatg tggtggctag gcaactgtgg tacttggatt
    17101 aagacaccag ctggtgctaa cgttgtcatg gacctttggt caaaccgtgg aaaatcaacc
    17161 aaaaaagtga aagatatggt tcgtgggcac caaatggcaa atatggcagg tgttcgtaag
    17221 ctgcaaccaa acttgcgtgt tcagccaatg gttatcgatc catttgctat caacgaacta
    17281 gactattact tagtttcaca cttccacagt gatcatatcg acccatacac agctgcagca
    17341 attctcaata atcctaagtt agagcatgtt aagtttatcg gtccttacca ctgtggacga
    17401 atctgggaag gatggggtgt tccaaaagaa cgtatcatcg ttgttaaacc aggtgacact
    17461 atcgaattaa aagatatgaa gattcatgca gtagaatcat ttgaccgtac ttgcttggta
    17521 actctcccag tgaacggtgc tgatgagaca ggcggtgaac ttgctggctt ggctgttaca
    17581 gatgaagaaa tggctcaaaa ggctgttaac tatatctttg aaacaccagg tggaaccatc
    17641 tatcatggtg cagattctca cttctcaaac tattttgcaa aacatggtaa agactttaaa
    17701 attgatgttg ctttgaataa ctatggtgaa aatccggtag gtatccaaga caaaatgaca
    17761 tctatcgacc ttcttcgtat ggcagaaaat ctgcgtacca aagtcattat cccagttcac
    17821 tatgatatct ggtctaactt catggcttct actaatgaga ttctagaact ttggaaaatg
    17881 cgaaaagatc gcttgcaata cgatttccat ccatttatct gggaagttgg cggtaagtac
    17941 acttatcctc aagatcaaca cttagtagaa taccatcatc cacgtggttt tgatgattgt
    18001 tttgaacaag actctaacat tcaatttaaa gctttgctat aatataaaaa tattctttgg
    18061 aggttatccg tatgttgcat gatacggata attttcatat aatagtaaaa tagaatgtgt
    18121 gattcaataa tcacctcaaa tagaaaggaa attctatgtc aaatctatct gttaatgcaa
    18181 ttcgttttct aggtattgac gccattaata aagccaactc aggtcatcca ggtgtggtta
    18241 tgggagcggc tccgatggct tacagcctct ttacaaaaca acttcatatc aatccagctc
    18301 aaccaaactg gattaaccgc gaccgcttta ttctttcagc aggtcatggt tcaatgctcc
    18361 tttatgctct tcttcacctt tctggttttg aagatgtcag catggatgag attaagagtt
    18421 tccgtcaatg gggttcaaaa acaccaggtc acccagaatt tggtcatacg gcagggattg
    18481 atgctacgac aggtcctcta gggcaaggga tttcaactgc tactggtttt gcccaagcag
    18541 aacgtttctt ggcagccaaa tataaccgtg aaggttacaa tatctttgac cactatactt
    18601 acgttatctg tggagacgga gacttgatgg aaggtgtctc aagcgaggca gcttcatacg
    18661 caggcttgca aaaacttgat aagttggttg ttctttatga ttcaaatgat atcaacttgg
    18721 atggtgagac aaaggattcc tttacagaaa gtgttcgtga ccgttacaat gcctacggtt
    18781 ggcatactgc cttggttgaa aatggaacag acttggaagc catccatgct gctatcgaaa
    18841 cagcaaaagc ttcaggcaag ccatctttga ttgaagtgaa gacggttatt ggatacggtt
    18901 ctccaaacaa acaaggaact aatgctgtac acggcgcccc tcttggagca gatgaaactg
    18961 catcaactcg tcaagccctc ggttgggact acgaaccatt tgaaattcca gaacaagtat
    19021 atgctgattt caaagaacat gttgcagacc gtggcgcatc agcttatcaa gcttggacta
    19081 aattagttgc agattataaa gaagctcatc cagaactggc tgcagaagta gaagccatca
    19141 tcgacggacg tgatccagtc gaagtgactc cagcagactt cccagcttta gaaaatggtt
    19201 tttctcaagc aactcgtaat tcaagtcaag atgccttgaa tgttgtggca gctaaattac
    19261 caacctttct aggtggatca gctgaccttg ctcactcaaa catgacttat atcaagacgg
    19321 atggacttca agacgatgcc aatcgcttga atcgtaacat tcagtttggt gttcgtgaat
    19381 ttgcaatggg aacaatcttg aacgggatgg cccttcatgg tggacttcgt gtatacggtg
    19441 gaactttctt cgtcttctct gactatgtga aggcagctgt ccgcttgtca gccttacaag
    19501 gacttcctgt gacttatgtc tttacccatg attcaatcgc agttggggaa gatggtccga
    19561 ctcatgaacc agttgagcat ttagcaggtc ttcgtgctat gccaaatcta aatgttttcc
    19621 gtccagcaga tgcgcgtgaa acgcaagcag cttggtacct tgcagtgaca agtgagaaaa
    19681 caccaactgc ccttgtcttg acacgtcaaa atttgactgt tgaagatgga acagacttcg
    19741 acaaggttgc taaaggtgct tatgttgtat atgaaaatgc agccgacttt gataccatct
    19801 tgattgcgac aggttcagag gttaatcttg ctgtctcagc tgctaaagaa ttggctagtc
    19861 aaggcgaaaa aatccgcgta gtcagcatgc catctacaga tgtctttgat aaacaagatg
    19921 cagcttacaa ggaagaaatt cttccaaatg cagtccgccg tcgtgttgca gtcgaaatgg
    19981 gtgcaagtca aaactggtac aaatatgttg gtctcgatgg tgccgttcta ggtattgata
    20041 ccttcggagc ctctgcccca gcaccaaaag tattggcaga atatggcttt actgtagaaa
    20101 atcttgtaaa agttgttcga aacttgaaat aatcctaaaa atcagggcgt aagctctggt
    20161 ttttcttacc agaaaagtaa ggtacaatct tgtaaaagta gctgaaattt gatatagtag
    20221 tcctatgtaa aagacaaagg agaaaacaat gaatccaaat attacttttt taatcatgct
    20281 tgtaggtatg atggccttga tgttctttat gcaacgttct caaaagaaac aagctcaaaa
    20341 gcgtatggaa agcttaaata aactacaaaa aggctatgaa gtgattacaa tcggtggact
    20401 ttatggaaca gtcgatgaag tagatacgga gaagggaaca atagttcttg acgtagatgg
    20461 agtttacttg acttttgaac tagctgctat caagacagta ttaccgctga aagaaacagc
    20521 ttcactagaa ggcgcaattg aaaaataaga cgggatcacg aactcccgtt ttctataaaa
    20581 gaaaggaaat gggatgaaaa aattagtctt tgtctgtctg ggaaatattt gccgtagccc
    20641 tatggccgag tttgttatga aatcaatgac agataactac gaaatccaaa gtcgagcaac
    20701 ttcctcttgg gaacatggca atccgattca taaggggact cagggaattt ttcaagagta
    20761 tgagattcct tatgacaaga acaagacatc gcttcagatt agtaaggaag attttgaagc
    20821 ctttgattat attatcggaa tggacgcttc aaatatttct gacttacgtc agatgtgtcc
    20881 agtagactgt caagataaga tttactcatt ttcatctgaa agtgttccag acccttggta
    20941 tacaggagat tttgaagaaa cctatcgacg tgttcaagag ggctgtcaag cttggttaga
    21001 acgtttagaa aaggagagtt aaggtggaaa atcttacgaa tttttacgaa aagtatcgtg
    21061 tctatctgac tcgtccacgt ttagagcttt tggcagtagt taccattgtt ttctgtgctg
    21121 tactcgtctt ttttctaaat attccaggaa aaggtgtctt aaaactcgat aatggaacga
    21181 ttgtttatga tggcagtctt gtccgtggta aaatgaatgg ccaaggtacc attaccttcc
    21241 aaaatggaga ccaatataca ggtggcttca acaatggagc cttcaacgga aaaggtacct
    21301 ttcaatctaa agaaggctgg acctacgaag gtgattttgt aaatggtcag gctgaaggaa
    21361 aagggaaact aacaacagaa caagaagtcg tttatgaagg aacttttaaa caaggcgttt
    21421 ttcaacaaaa ataaagcctc cttatcaaag gaggtattat tagaatcaca aggtaagcgc
    21481 ttacctgtaa atccctttct ttccaaatcc ctcttccaag caagtttgtg aaataaaaaa
    21541 tatttgaaat aaatttcaca aacttcaaag ataaaacttg ataagaaaag aaaatgagaa
    21601 aagtttcaca agagtttaaa aattctttgt gaaatgttta tgaaactgtt tacaaagttg
    21661 aaataatgcg ttataataaa cttgtgaaaa aattaacaaa ggatatcgtt ccttgaaagc
    21721 tatggaggaa aatatggctg ataaaaaaac tgtgacacca gaggaaaaga aactcgttgc
    21781 tgaaaaacac gtagatgagt tggttcaaaa agctctagtt gcccttgaag aaatgcgtaa
    21841 attggatcaa gaacaagttg actacatcgt tgccaaagca tcagtagcag ctttggatgc
    21901 ccacggagaa ttggctttac atgcctttga agaaacagga cgtggtgtat ttgaagacaa
    21961 agcaactaag aacttgtttg cctgtgaaca cgtagtaaac aacatgcgcc acactaagac
    22021 agttggcgtt atcgaagaag acgatgtaac aggattgact cttattgctg aaccagttgg
    22081 tgttgtttgt ggtattactc caacaacaaa cccaacatca acagcaatct tcaaatcatt
    22141 gatttcattg aagacacgta acccaatcgt ctttgccttc catccatcag cacaagaatc
    22201 atctgctcat gcagctcgta tcgtccgcga tgcagctatc gcagctggtg ctcctgaaaa
    22261 ctgtgtgcaa tggattactc aaccatctat ggaagcaaca agtgccctta tgaaccacga
    22321 aggtgttgcg acaatccttg caacaggtgg taatgccatg gttaaggcgg cttattcatg
    22381 tggtaaacca gctcttgggg taggtgccgg aaacgttcca gcttatgttg aaaaatcagc
    22441 aaacattcgt caagcagcac acgatatcgt catgtctaaa tcatttgata acggtatggt
    22501 ctgtgcatct gaacaagcag ttatcattga taaagaaatt tacgatgaat ttgtagcaga
    22561 gttcaaatct taccacactt actttgtaaa caaaaaagaa aaagctcttc ttgaagagtt
    22621 ctgcttcggc gtcaaagcaa acagcaaaaa ctgtgctggt gcaaaattga acgctgacat
    22681 cgttggtaaa ccagcaactt ggattgcaga acaagcagga tttacagttc cagaaggaac
    22741 aaacattctt gctgcagaat gtaaagaagt tggcgaaaat gagccattga ctcgtgaaaa
    22801 attgtcacca gttattgcag ttttgaaatc tgaaagccgt gaagatggta ttactaaggc
    22861 tcgtcaaatg gttgaattta acggtcttgg acactcagca gctatccaca cagctgacga
    22921 agaattgact aaagaatttg gtaaagctgt taaagctatt cgtgttatct gtaactcacc
    22981 ttctactttt ggtggtatcg gggacgttta caatgccttc ttgccatcat tgacacttgg
    23041 atgtggttct tacggacgca actcagttgg ggataacgtt agtgccatta acctcttgaa
    23101 tatcaaaaaa gtcggaagac ggagaaataa catgcaatgg atgaaacttc cttcaaaaac
    23161 atactttgaa cgtgattcaa ttcaatacct tcaaaaatgt cgtgacgttg aacgtgtcat
    23221 gatcgttact gaccatgcca tggtagagct tggtttcctt gatcgtatca tcgaacaact
    23281 ggaccttcgt cgcaataagg ttgtttacca aatctttgcg gatgtagaac cggatccaga
    23341 tatcacaact gtaaaccgtg gtactgagat tatgcgtgcc ttcaaaccag ataccatcat
    23401 cgcactcggt ggtgggtctc caatggatgc tgccaaagta atgtggctct tctacgagca
    23461 accagaagtg gacttccgtg accttgtcca aaaattcatg gatatccgta aacgtgcctt
    23521 caagttccca ttgcttggta agaagactaa attcatcgcg attccaacta catctggtac
    23581 aggatctgaa gtaacaccat ttgccgttat ctctgataaa gcaaacaacc gtaaataccc
    23641 aatcgctgac tactcattga caccaactgt ggcaatcgta gatcctgctt tggtattgac
    23701 agttccagga tttgttgctg ctgatactgg tatggacgta ttgactcacg cgacagaagc
    23761 atacgtatca caaatggcta gtgactacac tgatggttta gcacttcaag ccattaaatt
    23821 ggtctttgaa aatctcgaaa gctcagttaa gaatgcagac ttccactcac gtgagaaaat
    23881 gcataacgct tcaacaatcg ctggtatggc ctttgccaat gccttcctag gtatttctca
    23941 ctcaatggcc cataagattg gtgcgcaatt ccacacaatc cacggtcgta caaatgctat
    24001 cttgcttcca tacgttatcc gttacaacgg tacacgtcca gctaagacag caacatggcc
    24061 taagtacaac tactaccgtg cagatgaaaa ataccaagat atcgcacgca tgcttggact
    24121 tccagcttct actccagaag aaggggttga atcttacgca aaagctgtct acgaactcgg
    24181 tgaacgtatt gggatccaaa tgaattttag agaccaagga attgacgaaa aagaatggaa
    24241 agaacattct cgtgaattag ccttcctggc ttatgaagac caatgttcac cagctaaccc
    24301 acgtcttcca atggtagacc atatgcaaga aatcatcgaa gatgcatact atggctacaa
    24361 agaaagacca ggacgccgta aataattgtt tatcagtcta gaagcaagac aaaaactcaa
    24421 tttgagggaa agatccagta atttttctat gataaaaggc atcctatcaa ggtttttgaa
    24481 cacctgatag gatgcctttt tatgatattg aggccttttt gccctttttg aaaaactaga
    24541 atagaaacaa aatatataat agattgaaac tggaatagta cacttctgct tctaaaacat
    24601 tgttagaatt cgatttgact gtcctgatcg atttgtccta ttcctatttc attttactat
    24661 ataaaaaata tagtatagta gactgaatct aaaatagtac gaaacaattg ctaaaacatt
    24721 tatagaaatt aattttactt tcctgataga gttgtttaca tcttatttca attcactata
    24781 gtttaattta agagtagtat ttactaaggc ccaattaaaa tcaaagagca aactagaaaa
    24841 cgagtgccat tcagctcaaa acactgattt gagattgcag ataagactag ccccctcatt
    24901 aacagattta cgataaaacg atgacaaggt gtgttgcttt ttgatttcta aagagtataa
    24961 tgatagatct ctataaaata agtgcgaagg aaatgagctt ttatagtcct ttcgttttaa
    25021 aatactatct cagatattct tatatcgaca agaagttttt gagtcattcc ctcatcatac
    25081 atattaaata aatagtggct cattcaattt ttcactagaa taataagcta gtatagtaaa
    25141 ctgaaataag atataaacaa ataaattgga gcttaacatc tatttccagc aattttttag
    25201 aaactgcagt ggactattct agattcaaca tattataaaa actagagtaa aagaaaagga
    25261 ttggatcttg tgtaatgcag gatccaatcc tttcaatcat tttgtccaac ttttggaggt
    25321 tcctacaatg tagtcgtcat taataaagac agatgggaac gacagtgttc ctatttattt
    25381 tgatagagat cgatgaattc tttagatagc aactgaataa tctctgttga agccatttgg
    25441 tcttctgcat gcataaatag caaggagaat cctatttttt ctccagtagc ttctttttgt
    25501 atgagattgg agtgaatctt gtgcgcttct actaaggagt cttccgcttc ttcaacttta
    25561 attttcgctt cttttaaatt tcctgcctta gctagttgga tggcttcaat aaaggatgat
    25621 ttggctgctc cactattggc aatgagctga aaacagatat attccatttc ttctgtcatc
    25681 ttatttctcc tatccattca agtgcttgtt ccagaacttt tgctccattc atcattccgt
    25741 aatcccgcat atcaatggta tctacaggga tatttcctgc aatttctttc acagcaagta
    25801 actcataacg aatttgtggc ccaattagaa tgacatctgc ttcatggata ttttttttag
    25861 cttctgtcat tgattttgct tggatagaaa tttcaatccc acgttcagtc gcactttgtt
    25921 gcattttttt aacaagcata cttgtcgaca ttcccgcatt acatactaat aaaatttgtt
    25981 tcataatctt aaccttccat ttcttgttca acaactttgt cattaacttt gataaatgga
    26041 atgtatagaa gaactccaag tgcaaagatg atgaattgaa ctagaactgc tctcacgtcc
    26101 cctgctgttg ctaaccatgc atttaagaat actggtgtag tccaaggaac ttgtataaat
    26161 gcaggactca tgaatcctgt aactgttgct aagtagctga ttaaaatacc aagtactgga
    26221 actgtgataa atggaatagc taatgaaatg ttataaacga ttgggtaacc gaataatact
    26281 ggttcattga tattgaagat accaggtcca aaagataatt tagccacgtt tttagaaaca
    26341 gcattgcgac ttactaagaa tgttgctatt aataaacata atgtagatcc actaccaccc
    26401 attaaagcga atgtttgtat ttgtgataag ttgatgatgt gtggaatggc ttgtccatta
    26461 tttgctgcag tgatgttttc agtaatgtta attaatagta atggttctag gatggcactg
    26521 taaataactg cttggtgaat accaaatagc cataacatat ttcctaaaga gtaaataata
    26581 atgaccccga ttaagcttgt accaatatga cgaattggtt cttgaataaa gattgtaatg
    26641 attgagatta agttcattcc agttatattg aataataatg ctgaaacaac cccaaataag
    26701 gagatgacgg tcatgactgg aagtaatacg ctaaatgatc tactaacagc tggtggaata
    26761 ttttcaccaa ggttcatttg taaagcttta acgtttgata attcaatgaa taattctgtt
    26821 gcaataatcg ctacgataac cccggcgaac attgcgcctg tacctgtgtt gttgaatgaa
    26881 agaacacctg aaatgtttac cgcatctttt gctccgtcag gaactacaga aactgtattt
    26941 ggcatcatca caattaaaga aactaatgat agcattgatg ctgctaacgg gttttcgaaa
    27001 tctctgtttt tagctaagaa ataaccaacc attacagcaa taatcatacc tgaaatactt
    27061 aaagtaccgt ttgcaattgt tattccccaa tattggaatc ttgttaatgt atccccttgg
    27121 aaaatccact taaataccgt gttgttcaaa agaacgatta aacctgccaa aatatataat
    27181 ggcattactg ttacgaatgc atctcttagg gtttttaaat gaatttggtt ccctagttta
    27241 ccagcaaagg tggcaaattg atctataaat tttgagtttt tcatctgaat atctcctctc
    27301 tttactcctc aatttctact tcaaaaccgt tattgtcact tactttgcga taccatcttc
    27361 ctgatctctt gatggttctc ttttgcgttt ctaaatcaac ggagataaat ccgtaacgat
    27421 tcttatatgc attattccaa gaccagcaat caaatgcggt ccaagcgtgg tatccaaaac
    27481 agtgacttcc ctcttcaatg gctttatgta gccatcttaa atgttcttca taaaattcaa
    27541 tacgatacac gtcatcgata actccatttt caccgataaa ccgtgcttcg ttttcaacac
    27601 ccattccgtt ttcactgata aaccatggaa tattaccata ttctttcttc acaatcatag
    27661 caatatcata aatggctttc ggaaaaattt cccaaccacg atatggattc atgcgacgct
    27721 ccggccattc atactctttg aagtattggt ctggcatcca gggcgtctga tattcctcag
    27781 gatttgcttg tgcttgaaca cgttttggat ggtagtagtt tactccaaga aaatcaaccg
    27841 tatttgattt catcagttga agctcttttt cggtatgact ccataacacg ccatctctct
    27901 ctagctgttt taccaatctt tctgggaaag ttcctttaac agctggattc aagaagactt
    27961 tgttaaagaa gtcatctgta aatcgacttg cttctaagtc ttctggagaa ttacttcttg
    28021 gataagcagg tgtcaagttt aaaataatcc caatctttcc atcaagtcct aatgagcgat
    28081 atagttgaat cacttttgca ctagcaaggt ttagattata gatgacttgt acggcctctt
    28141 ttccctttcc ttttagattt ggataatgga aagcatataa gtatcctgct tctggaatga
    28201 ccattggctc attgaaagtt gtccagtaat gaaccttatc tccaaagcat gtgaaagcag
    28261 tcttggcaaa cttcacgaat aactccacta catgtttgct ttcccaacca ccgtattttt
    28321 gaagaagttc cactggtaaa tcaaaatgat gtaaattcat cacaagatcc atctggttct
    28381 ttttagcttc ttcaatgatg gcattgtaga aagcaatacc ttttggatca ggctcacctg
    28441 tctctaaatt cttgatgagt cgactccatt ggatggaagt gcggaaagaa ttaactccaa
    28501 tttccttcat caagtggaaa tcttcggtgt aagtatgaaa aaagttactg gctacaagag
    28561 gtccgacatt atcgaaaaaa tcttctggat gcgttttgaa ccagtagtcc atcacatttt
    28621 catgtacttt tccatattga ccttctgtct gaggtccgct agaagcagct ccccaccaaa
    28681 acagattagg aaatactaac ttttttttca tgctcaacct cctttctatt attctataca
    28741 taaagtatag cataatttta aaatttgtct agacattttt aaaaattgtt gatacatatc
    28801 ttgtgtttgc ctcatttctt gaactttgtt atactactat tagaatatta tagagagaac
    28861 cagattaaat gagtacaaaa tatttattta tttacaatga gattcgtgaa aagattcttt
    28921 gtaataaata taccatgaac gaacaattgc ctgatgaaat gacattagct aaacagtttg
    28981 cctgtagtcg aatgacgatc aaaaaagctt tagacttgtt agtttctgag ggcttaattt
    29041 ttagaaaacg tgggcaggga acctttgttc tctctcgtgg cagctcaaaa agaaaattaa
    29101 tcgttccaga aagagatatc cggggattga caaaaatatc tgaagatgct cattctacaa
    29161 ttgactcgag gattattcac ttcaaattag aatttgcaaa tgaattttta gcagaaaaac
    29221 tacaggtcgc tttgcagagt ccagtttata atatttaccg cctgcgtatt attgacggta
    29281 aaccttatgt tctggaacaa acttatatga gtaccgatgt tattccaggt attactgaag
    29341 atattttaca aaaatcgatt tacaattaca ttgaaggaaa gttaggattg catattgcca
    29401 gtgctacaaa aatcttgcga gcttcttcta gttcagaaaa tgagcaacat tacttgcagc
    29461 tccttccaac ggaaccggta tttgaagtag aacaagtggc ttatttggat aacggaactc
    29521 cgtttgagta ctcgattagt cgtcatcgct atgatttatt tgaatttaat tcttttgcat
    29581 tacgacattc ctcctaggag aaaatgtgaa aatgaagcca atcttttaca gactctagtt
    29641 taagaaaaat ttaaaacagg gcaagaaggt cccatctatg cttaaatggt ttctcttttc
    29701 taaataagat ggctttaaaa gagtgatcgt tgtatccatc atgttgaaaa atatcttcgt
    29761 atagcttata gagtaggtac tgaaattgtt cacctgatct acttcttata gttatttagt
    29821 tttaaatagt gtttcaaaca ttcttacact gacgagaagt ttttgagtct tttcttgtaa
    29881 cacatatagt atactgtggt tagaatagta gactgtgact tctaacaaat tgctagaaat
    29941 gaatttcaat ctcccaattt atttacttat atattatttt aatatattaa acaaattctg
    30001 aatcataatc atttaaaaaa attttatttt tttatttttc attacgaata atatagatga
    30061 aggggaaaga gtatgaaaac agaactgttt cttttgctat tagttcaaaa ggagaaaaaa
    30121 tgaaagtaga aaatatttcg tatagggtgg atcatcgtat attgtttgat aatatttctt
    30181 ttgctacttc gagttcaggc gtgacattaa ttactggtaa aaatggtaca ggaaagtcaa
    30241 ctttactata gtagattgaa actagaatag tacacctcta cttctaaaat gttgttagaa
    30301 atcgatttga ctgtcctgtt cttatttcat tttactacat ctcaaattga gtatgacgaa
    30361 gtgcgctccc atgtcatggg aacgcacttc gtcatatttt tcatattctt gaatccatcg
    30421 ataaagacta ttgggatgaa tttttaaagt tgaactaatc atttttacag gatgaggttt
    30481 acagcagaga gtttgaaggc tttatcaaag gtttttcttg gcataatgac ttttcctcgt
    30541 ttccacttaa ttttgtgtct actttattat accaagtcca cccttaagtt agataataaa
    30601 tctaacttaa ggaagctaga aggatgagaa tccaggtggt caagagtccc aaacttaagc
    30661 tgatggggac acccagaata atttgctttt tgaaggcaag gccacgttcc tctatattgg
    30721 gaagtgagag ttgaatgaga gaaccagctg atgaaaaggg tgagatatta gtagatagag
    30781 cgccaataac ggtggctgtt gtgagtaagt gaatatcaat ctgaggattt tgagcactga
    30841 tgatagcaat gatgggaaag agggctggag ctacaacgga tagggtggaa ctaaagagtg
    30901 acatcactcc ggctatcaca caaaagaaca gaggtaacca gaaatgagga atggttgttg
    30961 tcatgaggtg ccctatcagt gtgactaaac ctgacttgac cgctagagac attagtaagc
    31021 tcatgccgca gagcatgata attgtagccc agggaacctt agccaaaatg gcttcttgct
    31081 tccctaattt gagccttaag gcgaggcaga ccatgagtat tgagacaaag ccaatatcaa
    31141 atgtttttcg ataagtagct atccaggcga tgtttgggaa aatgagatgc aacaagggaa
    31201 aaagccagac caaaaccatg ctgctgatca tgagcaaggt ggtttgtctt tgaaccttgc
    31261 tgaggagtgg tggttggtca atagtcaagg atgagtttgt tcttccctta ctatagtggc
    31321 tgtaacagga taataaaagc aagacgatga gtgggtagat aatgctgacg ataaagatat
    31381 gattgccaag tgaaaaagct tgctcttccc atcccatttg cttaaacagg ccttgaaaga
    31441 caatgcctga gctactggtt atcaaattag cccctcctga agctccccaa ttgacggctt
    31501 gagctccaat caaagggtgt ttgtccgctt tttgacagag ggtaatcgct agaggacagc
    31561 aaacggccat agtagtgaaa aatccagcac ctaaagcaga caaaagggtt gccatcaggt
    31621 ataaaatcat gtagagggcg ttagggtggg tgcgtgtgcg gtagagaatg tgttgagcca
    31681 aaacatcaag agtaccgtta gttgttgcaa cgttataaaa gagagagacg ctaaaaatgg
    31741 taaaaaagag tgaggttggc caaaaatgaa gaagttcttt ggggcttaat cccatgagag
    31801 tggttgcgat gaggtaagaa aaagcaatag ccagcaggcc aatattgatt ttggtgcggt
    31861 aaccaattcc aatggctaga gcaatggcgc taatcattat taaatgaatc attgaattgt
    31921 cctttcagtt agaatatgga aatagattgg caattttggc gctcaaaaga ccacctgttt
    31981 cctattggta cttgactatt atacacaaaa aaaatacaat tgtcttgaca attgtattga
    32041 cacttgttag aattaaaaat gaggtattca ggcttgtgat ttcctatgga agttaatagt
    32101 aattgcctct agtgcttaca agtgatatta aaaatagagg acttagtgat gtcaatcatt
    32161 tcaactgatt taaccccttt tcaaatagat gatacattga aagcagcctt gcgagaagat
    32221 gttcattccg aagattacag taccaatgcc atttttgatc atcatggcca agccaaggtg
    32281 tcgctttttg ccaaggaagc tggtgtttta gcgggactaa ccgtttttca aagggttttt
    32341 accctatttg atgccgaggt gaccttccag aatcctcatc aatttaagga tggggatcgt
    32401 ttgactagtg gcgatttggt tttagaaatc ataggctcgg tgagaagtct cttaacatgt
    32461 gaacgcgttg ccttgaattt tttacaacat ttatcaggga ttgcttcgat gacagctgct
    32521 tatgtagaag ccttaggcga tgattgcatt aaggtatttg atactcgaaa aactactcct
    32581 aatttacgtc tttttgagaa atatgccgtg agagttggcg gtggctataa tcatcgcttt
    32641 aatttatcag atgctatcat gctaaaagac aatcacattg cggcagtagg tagtgttcaa
    32701 aaggcaattg ctcaagcgcg tgcctatgcc ccttttgtga aaatggtcga ggtggaagtg
    32761 gaaagccttg ctgctgccga agaagctgcg gcggcgggtg ctgatattat catgttggat
    32821 aatatgtcat tggaacagat tgaacaggct attaccctaa ttgcaggacg ttctcggatt
    32881 gaatgttctg gaaatattga tatgaccact attagccgtt ttcgtggttt agcgattgat
    32941 tacgtctcca gtggtagttt aacccatagt gctaagagtc ttgatttttc catgaagggg
    33001 ttaacctacc ttgatgtcta agttgtaaaa taaactaact ttttaaagga tgtttttcct
    33061 ctagaacgag ttttatgtca gatagtttaa acgcctcttc aaatatagta aaatgaacca
    33121 aaaatagtac acaatgtggt ataatctttt tatggcatat tcaatagatt ttcgtaaaaa
    33181 agttctctct tattgtgagc aaacaggtag tgtaacagaa gcataacacg ttttccaaat
    33241 ctcacgtaat accatttatg gctggttaaa gctaaaagag aaaacaggag agctaaacca
    33301 ccaagtaaaa ggaacaaaac caagaaaagt tgatagagat agacttaaaa actatcttac
    33361 tgacaatcca gatgcttatt tgattgaaat agcttctgaa tttggctgtc atccaactac
    33421 catccactat gcgctcaaag ctatgggcta cactcgaaaa aaaagaacca cacctactat
    33481 gaacaagagc cagaaaaagt agccttattt cttaagaatt ttaatagttt aaagcaccta
    33541 gcacctgttt agattgatga aacaggattc gatacttatt tttatcgaga atatggtcgc
    33601 tctttaaaag gtcagttaag aagaagatat tagaggattt ctttggttgc aggtctaacc
    33661 aatggtgagt taatcgctcc aatgacttac gaagagacga tgacgagcga cttttttgaa
    33721 gcttggtttc agaagttttt cttaccaaca ttaaacacac catcggttat tattatggat
    33781 aatgtaagat tccatagaat ggggaagcta gaatttttat gcgaggagtt tgggcataaa
    33841 cttttacctc ttcctcccta ctcgcctgag tacaatccta ttgagaaaac atgggctcat
    33901 atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttacga ggctcttttg
    33961 tcttgttctt gtttcaattg actatatatc acggatacag ttgggaaaga agctattaat
    34021 tatttggaga gtccttttgg gatgaacatg tcaaatatta ctatagatgg gcaagaaatg
    34081 gatctgagtc aaacgatgcc ttcttatgct caagtagtga gtctttatga tgatacaagt
    34141 atctctgtta gtaataatga gacggacaaa gtgttggctg gatccctcta tactgataca
    34201 aatgaacagg gattaacgat tccaagcagt ttactaaaaa attggaatga acagacagga
    34261 aaaaatttga cagctaatga tcttattggc aaatcagtct cagccagcat tgtagaaagt
    34321 gctgccgaag ctagtaagat tgctcaattt caaacgaaga ttgtatgtgt aatcaatgat
    34381 gaagatgaca tggaggacag caacagtttc atgctgtctc atcaaatgga aacgattttg
    34441 aaagaggctg gatttacgaa agctgtatct tattttatct tggaactcaa agatccatca
    34501 cagacaaaag tagtaacaga agaattacag aaaaataaga agtatactgt gctttctcaa
    34561 cagaaagttc ttgatattgt gattatcttt attcgtgtta ttcagggatt attgattgtg
    34621 ctttcatcac aagctattgt ggtagcagcg gttatgattg gtatcattat ttacatcaat
    34681 atcatgcagc gttccaagga aataggtgtc atgaaggcag ttggttatca gaatcgtgat
    34741 gtcaaaggaa tttttattta cgaggctatc tggattgtag gcatcgcctt gctgctggca
    34801 tttttggttg cacaaggggt gggaagtttg gcgaatgcga ttgtaagtca cttttaccca
    34861 tccatcacta aagtttttga attaaatctt ttatctgttt taggaactct agttttcgct
    34921 ctattacttg gttatgtctc agcctacttc ccggcgcgta agattagtaa aatggatcct
    34981 gtagaaccgt tacgctatga atagtaaggg attccttgat ttacagtctt aaaaagaaac
    35041 taacatagaa aaacaatggc catacttgca attcaactca aatagttgta taataggttt
    35101 gttgaaaggt gatttgtagt gattcaagtt actcttttca caataaaaat ttcatgattt
    35161 tcataaggag gaaatcacta atggtagtta aagttggtat taacggtttc ggacgtatcg
    35221 gtcgtcttgc tttccgtcgt atccaaaacg tagaaggtgt tgaagttaca cgcatcaacg
    35281 accttacaga tccagttatg cttgcacact tgttgaaata cgacacaact caaggtcgtt
    35341 tcgacggtac tgttgaagtt aaagaaggtg gatttgaagt taacggtaaa ttcatcaaag
    35401 tttctgctga acgtgatcca gaacaaatcg actgggctac tgacggtgta gaaatcgttc
    35461 ttgaagctac tggtttcttt gctaagaaag aagcagctga aaaacacctt aaaggtggag
    35521 ctaaaaaagt tgttatcact gctcctggtg gaaacgacgt taaaacagtt gtattcaaca
    35581 ctaaccacga cgttcttgac ggtactgaaa cagttatctc aggtgcttca tgtactacaa
    35641 actgcttggc tccaatggct aaagctcttc aagacaactt tggtgttgtt gaaggattga
    35701 tgactactat ccacgcttac actggtgacc aaatgatcct tgacggacca caccgtggtg
    35761 gtgaccttcg ccgtgctcgc gctggtgctg caaacatcgt tcctaactca actggtgctg
    35821 caaaagctat cggtcttgta atcccagaat tgaatggtaa acttgatgga tctgcacaac
    35881 gcgttccaac tccaactgga tcagttactg aattggtagc agttcttgaa aagaacgtta
    35941 ctgttgatga agtgaacgca gctatgaaag cagcttcaaa cgaatcatac ggttacacag
    36001 aagatccaat cgtatcttca gatatcgtag gtatgtctta cggttcattg tttgacgcaa
    36061 ctcaaactaa agttcttgac gttgacggta aacaattggt taaagttgta tcatggtacg
    36121 acaacgaaat gtcatacact gcacaacttg ttcgtactct tgaatacttc gcaaaaattg
    36181 ctaaataatt cttgagttga tagaaagcaa ggctttgtgg tcttgctttt tatatggaaa
    36241 aatggatgac acgatcatcc attctttttt aattcttttt caaatgtatt tgaaagggta
    36301 gtgaaagtta gcttctctaa agtaagtggg tgggtaaagg aaagtcggaa ggcatgaagc
    36361 ataagccgac ttgtctttga tttactatta tagagagggt cgcccaggat aggaagatta
    36421 tgatgcgaaa ggtgcacacg aatctgatgg gttcgccctg tctttagctt gcaacgagcc
    36481 aaggaagtct tgtttgagaa ttgctttaat ctgcttacat gcgtttcagc atattgccca
    36541 ttttttgcat caactattct ttttctacga tcatggcgat cacgtccaat tttgtctctg
    36601 aaaacaagtt cttttctgtt gatatttcca tcaactagag cccaatattc tctagaaatc
    36661 tcttttttct ccaataagcg attgagaatg ggcaggataa aaggattttt ggcaaagaga
    36721 actaagccac tggtttccat gtccagacga tgaacgacat agcaggtttg gccaacatag
    36781 gtactgacat ggttaagaag ggcaatttcg tttggttgat taccatgcgt tttcatcccc
    36841 tctggtttgt ttacaataat caagtgttga tcttgataaa cttcctgcac taagtctggg
    36901 ttgccccaag ggatcgtctt ttgggaataa tcttcctcgt caaaagtcaa ctggcaaaca
    36961 tctccaggat ttacgatttc gttccagtgg acttcttctt gatttatcaa aatatgtttc
    37021 ttgattctca aaaaatgacg gatttttcta gggatgagga gttgttcctc aagtaattgc
    37081 tttactgtca tttgaggtag agaggcgggt aatgtaaatg tgaattgcat acagatattg
    37141 taacaaaaaa agccctattt ggataggaaa tagctaaatt cttgtcttcc tatgatgaag
    37201 atgataaaat aaacgcatga aattagataa attatttgag aaatttcttt ctctttttaa
    37261 aaaagaaaca agtgaactag aggactctga ttctactatc ttacgtcgct ctcgtagtga
    37321 tcgaaaaaaa ttagcccaag taggtccgat tcgaaaattc tggcgtcgtt atcatctaac
    37381 aaagattatc cttatactag gtttgagtgc aggattgcta gttggaatct atttgtttgc
    37441 tgtagccaag tcgaccaatg tcaatgattt gcaaaatgcc ttgaaaactc ggactcttat
    37501 ttttgaccgt gaagaaaaag aggctggtgc cttgtctggt caaaagggaa cctatgttga
    37561 gctgactgac atcagtaaaa acttgcagaa tgctgttatt gcgacagaag accgttcttt
    37621 ctataaaaat gacgggatta actatggccg tttcttcttg gctattgtca ctgctggacg
    37681 ttcaggtggt ggctctacca ttacccaaca gctggctaaa aacgcctatt tatcgcagga
    37741 tcaaactgtt gagagaaaag cgaaagaatt tttccttgcc ttagaattaa gcaaaaaata
    37801 tagtaaggag caaattctaa ccatgtacct taacaacgct tattttggaa atggtgtgtg
    37861 gggtgtagaa gatgcgagta agaaatactt tggagtttct gcatcagaag tgagtctgga
    37921 tcaagctgcg actctggcag ggatgctcaa ggggccggaa ctgtataatc ccttgaattc
    37981 cgtagaagat tctactaatc ggcgcgatac tgtcttgcag aatatggttg cagcaggata
    38041 tattgataaa aaccaagaaa cagaagctgc tgaagttgat atgacttcgc aattgcacga
    38101 taagtatgaa ggaaaaatct cagattaccg ttacccctct tattttgatg cggtggttaa
    38161 tgaagctgtt tccaagtata atctaacaga ggaagagatt gtcaataatg gctaccgcat
    38221 ttacacagag ctggaccaaa actaccaagc aaatatgcag attgtttatg aaaacacatc
    38281 gctatttccg agggcagagg atggaacgtt tgctcagtca ggaagtgtag ctctcgaacc
    38341 gaaaacaggg ggagttcgtg gagttgtcgg tcaagttgct gacaatgata aaactggatt
    38401 ccggaatttc aactatgcaa cccaatcaaa gcgtagtcct ggttctacaa ttaagccttt
    38461 agttgtttat acgccagcag ttgaagcagt ctgggctttg aataagcagt tggataacca
    38521 taccatgcag tatgacagct ataaggttga taactatgca gggatcaaaa cgagtcgaga
    38581 agttcctatg tatcaagcct tggcagaatc gcttaatcta cctgctgttg ccactgttaa
    38641 tgatttgggt gtcgacaagg cttttgaggc aggcgaaaaa ttcggactca acatggaaaa
    38701 ggtcgaccgt gttcttggtg tcgccttggg aagcggtgtt gaaaccaacc ctcttcaaat
    38761 ggctcaagca tacgctgcct ttgcaaatga aggtttaatg cctgaagctc attttattag
    38821 tagaattgaa aatgctagtg gacaagttat tgcgagtcat aaaaattcac aaaaacgggt
    38881 gattgataag tctgtagctg acaagatgac cagtatgatg ttggggactt tcaccaacgg
    38941 taccggtatt agttcatcgc ctgcagacta tattatggca gggaaaactg gaacaactga
    39001 agcagttttc aatccggagt acacaagtga ccagtgggta attggttata ctccggatgt
    39061 agtgattagc cactggcttg gctttcctac cactgatgaa aatcactatc tagctggctc
    39121 tacttcaaac ggtgcagctc atgtctttag aaacattgcc aataccattt taccttatac
    39181 gccaggaagt acctttacgg ttgaaaatgc ttataagcaa aatggaattg caccagccaa
    39241 tacaaaaaga caagtacaaa ccaatgataa tagccagaca gatgataatt tgtctgatat
    39301 tcgagggcgt gcgcaaagtc tagtagatga agctagccgg gctatctcag atgcgaagat
    39361 taaggaaaag gctcaaacaa tatgggattc gatagtcaat ctatttcgct aagatgcttg
    39421 tcaaagccta gctttcttgt tataatggat aagatggagg cgttatggca ctaaaaaaag
    39481 caagcctagc ttgtgcggtt tgtggttcga gaaactattc aatcaagatc agcggaaacc
    39541 ccaagcctac acgactagaa gtaaataaat tttgtaagca ttgtggcaag tacactacac
    39601 acagagaaac gagataggag agagcgatgc gttttattgg agatattttt agacttctta
    39661 aagacacaac gtggccaact cgcaaggaaa gctggagaga ttttcgttct atcatggaat
    39721 acacagcttt ctttgtagta attatttaca tttttgacca gttgattgtt tcaggtttga
    39781 ttcgatttat taacattttt tagaagatta gtggagttaa ttacactaga aatcttctat
    39841 ttatgaaagg aaatatcatg gatagttttg ataaaggatg gtttgtttta caaacttatt
    39901 ctggttatga aaataaggtg aaagaaaatc tattacaacg tgcacaaacc tacaatatgt
    39961 tggataatat tctacgcgtt gaaattccaa cacaaacagt gcaagttgaa aaaaatggaa
    40021 agagaaaaga agtagaagaa aatcgctttc caggttatgt tcttgtagaa atggtcatga
    40081 cagatgaagc ttggtttgtt gttcgaaaca caccaaatgt tacaggattt gtcggatcac
    40141 acgggaacag atcaaaacca actccattat tggaacaaga aattcgtgac attttggtat
    40201 ctatgggaca aactgttcaa gaatttgatt tcgatgttga gattggtcaa actgtacgta
    40261 ttattgatgg tgcttttgca gactacactg gtaagattac agaaattgat aataacaaag
    40321 tgaaaatgat tatctctatg tttggtaatg acacagttgc agaagtaaac ctaaaccaaa
    40381 tcgcagaat
//
LOCUS       DAVDHC010000018        39740 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVDHC010000018 DAVDHC010000000
VERSION     DAVDHC010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.018"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            198..356
                     /locus_tag="VUR43_001296"
     CDS             198..356
                     /locus_tag="VUR43_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin class II family protein"
                     /protein_id="HET5412981.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAILGGV
                     AYAATCWW"
     gene            1075..3228
                     /locus_tag="VUR43_001297"
     CDS             1075..3228
                     /locus_tag="VUR43_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET5412982.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAALSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3241..4590
                     /locus_tag="VUR43_001298"
     CDS             3241..4590
                     /locus_tag="VUR43_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET5412983.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASENGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAEINLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4760..5467
                     /locus_tag="VUR43_001299"
     CDS             4760..5467
                     /locus_tag="VUR43_001299"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET5412984.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5669..9394
                     /locus_tag="VUR43_001300"
     CDS             5669..9394
                     /locus_tag="VUR43_001300"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET5412985.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQYNLGLSSLKSIRIVQVYDV
                     FDLVEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKDEQGMAMEVDDLLFIQDYFKSIGRVPTETEFKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIVMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9487..10929
                     /locus_tag="VUR43_001301"
     CDS             9487..10929
                     /locus_tag="VUR43_001301"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET5412986.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10966..11988
                     /locus_tag="VUR43_001302"
     CDS             10966..11988
                     /locus_tag="VUR43_001302"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET5412987.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLVSSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11985..12530
                     /gene="purN"
                     /locus_tag="VUR43_001303"
     CDS             11985..12530
                     /gene="purN"
                     /locus_tag="VUR43_001303"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET5412988.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12614..13123
                     /locus_tag="VUR43_001304"
     CDS             12614..13123
                     /locus_tag="VUR43_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET5412989.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13148..14695
                     /gene="purH"
                     /locus_tag="VUR43_001305"
     CDS             13148..14695
                     /gene="purH"
                     /locus_tag="VUR43_001305"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET5412990.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYTVVLDELSAN
                     GETTYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQAMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDRPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIAVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14817..16079
                     /gene="purD"
                     /locus_tag="VUR43_001306"
     CDS             14817..16079
                     /gene="purD"
                     /locus_tag="VUR43_001306"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET5412991.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16482..16970
                     /gene="purE"
                     /locus_tag="VUR43_001307"
     CDS             16482..16970
                     /gene="purE"
                     /locus_tag="VUR43_001307"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET5412992.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16957..18048
                     /gene="purK"
                     /locus_tag="VUR43_001308"
     CDS             16957..18048
                     /gene="purK"
                     /locus_tag="VUR43_001308"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET5412993.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18058..18285
                     /locus_tag="VUR43_001309"
     CDS             18058..18285
                     /locus_tag="VUR43_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET5412994.1"
                     /translation="MIQIIVNTFIEKDRTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18348..19646
                     /gene="purB"
                     /locus_tag="VUR43_001310"
     CDS             18348..19646
                     /gene="purB"
                     /locus_tag="VUR43_001310"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET5412995.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19701..23612)
                     /gene="strH"
                     /locus_tag="VUR43_001311"
     CDS             complement(19701..23612)
                     /gene="strH"
                     /locus_tag="VUR43_001311"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET5412996.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPETPATDKVASLPKTEEKPQEEVSSTPSDKAE
                     VVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEAKAEADKPE
                     TEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDLHLLVGNDG
                     LRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDLINYAKDKG
                     IGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAVAFTKALIDK
                     YAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEKFIAYANDL
                     ARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASSKLLAEKGH
                     QILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPIIGGMVAAW
                     ADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYTAESVAAVK
                     EAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKREVEKLAKNK
                     VISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTITANGKTYAS
                     DDVKKAIIEGTKAYYDDPNGTTLTQAEVTELIEYAKSKDIGLIPAINSPGHMDAMLVA
                     MEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIFNFGTDEYA
                     NDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYEDKDDVQFDK
                     DVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGFLKKAIENT
                     GKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFADHNKDYFRA
                     NYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLVANLKAALQ
                     GLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQENIITAGV
                     KGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGLAPTTEVKP
                     RLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGKEVKTLVNS
                     VVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAEESKALPQD
                     PAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(23928..24644)
                     /locus_tag="VUR43_001312"
     CDS             complement(23928..24644)
                     /locus_tag="VUR43_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5412997.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEHFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDHDH"
     gene            24992..26779
                     /locus_tag="VUR43_001313"
     CDS             24992..26779
                     /locus_tag="VUR43_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET5412998.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKNGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHCYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26776..27252
                     /locus_tag="VUR43_001314"
     CDS             26776..27252
                     /locus_tag="VUR43_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET5412999.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27280..28185
                     /locus_tag="VUR43_001315"
     CDS             27280..28185
                     /locus_tag="VUR43_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET5413000.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28172..28987
                     /locus_tag="VUR43_001316"
     CDS             28172..28987
                     /locus_tag="VUR43_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5413001.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28994..29398
                     /locus_tag="VUR43_001317"
     CDS             28994..29398
                     /locus_tag="VUR43_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5413002.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29646..30812
                     /locus_tag="VUR43_001318"
     CDS             29646..30812
                     /locus_tag="VUR43_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET5413003.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKYDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30928..31965
                     /locus_tag="VUR43_001319"
     CDS             30928..31965
                     /locus_tag="VUR43_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET5413004.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32172..33026
                     /locus_tag="VUR43_001320"
     CDS             32172..33026
                     /locus_tag="VUR43_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET5413005.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGEKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            33176..33416
                     /locus_tag="VUR43_001321"
                     /pseudo
     CDS             33176..33416
                     /locus_tag="VUR43_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
     gene            complement(33747..33839)
                     /locus_tag="VUR43_001322"
                     /pseudo
     CDS             complement(33747..33839)
                     /locus_tag="VUR43_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(33875..34171)
                     /locus_tag="VUR43_001323"
     CDS             complement(33875..34171)
                     /locus_tag="VUR43_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5413006.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(34161..34322)
                     /locus_tag="VUR43_001324"
     CDS             complement(34161..34322)
                     /locus_tag="VUR43_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET5413007.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            34392..35156
                     /locus_tag="VUR43_001325"
     CDS             34392..35156
                     /locus_tag="VUR43_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET5413008.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLVGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            35721..37100
                     /locus_tag="VUR43_001326"
     CDS             35721..37100
                     /locus_tag="VUR43_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET5413009.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            37114..37779
                     /locus_tag="VUR43_001327"
     CDS             37114..37779
                     /locus_tag="VUR43_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET5413010.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37914..37988
                     /locus_tag="VUR43_001328"
                     /pseudo
     CDS             37914..37988
                     /locus_tag="VUR43_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            38134..38672
                     /locus_tag="VUR43_001329"
                     /pseudo
     CDS             38134..38672
                     /locus_tag="VUR43_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            38739..39149
                     /locus_tag="VUR43_001330"
     CDS             38739..39149
                     /locus_tag="VUR43_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET5413011.1"
                     /translation="MYYLPVDFYRYLIGREGQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39265..>39740
                     /locus_tag="VUR43_001331"
     CDS             39265..>39740
                     /locus_tag="VUR43_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PavB family fibronectin-binding SSURE repeat
                     adhesin"
                     /protein_id="HET5413012.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPIPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENT"
BASE COUNT        10962 a         7687 c         9332 g        11759 t
ORIGIN      
        1 caggaagtct aatagtaaaa aagtgattag aaaacatctt ttttaaaaat agagatgatt
       61 ttgaaacaaa aaagctaatt caagacgttt cgatgccaat tcaagatttg gatgaaaaaa
      121 attaatagat actgttatac taaacttgtc aagtttgtaa caagacaaat attaaaaata
      181 aaaaagaggt attcgttatg aatacaaaaa agatgtcaca atttgaaatt atggatactg
      241 agatgcttgc ttgcgttgaa ggtggcggat gcaattgggg agattttgcc aaagcaggtg
      301 ttggaggagg agctatactt ggaggtgtgg cctatgcagc gacatgttgg tggtaattat
      361 ggattttaaa agttttatta ttggtttagt agttggtata tttggtcctt atatggatga
      421 tttaattaga aaaaaatttt taaagtcttc ggagaagaaa acagaaaaat ctgttaaaaa
      481 ataatcaaaa ctataaatga tgaatctgaa tcaaaattat tttgcgcatg taaagaggag
      541 tcttgcagta acgaatcaaa aaaaaggagt aactatgaat cgtaatttag aatggtgtta
      601 tctattatga ctataaatag atcataccag aggtggctta gaaatagcag ggacattaga
      661 aattgaagta actttaaata ggatgtcgta aatgttgcta tcaatgattt atttgtccca
      721 agcttgccta gggtgtcagt aaaaaatcat tttcctttca taccatattt ttagtaggta
      781 gaacgtttgt tctgcctatt tttttatcca aaaagtgcag ttgggaggga gataggctca
      841 tttgggaagg aagtccagtt tttgtttagt gattggggta agatagttgt tatcagatga
      901 gtttatactc ttcgaaaatc aaattcaaac cacgtcaacg tcgccttgcc gtatatatgt
      961 gactgacttc gtcagtccta tctacaacct caaaacagtg ttttgagcag cctgcggcta
     1021 gtttcctagt ttgctctttg attttcattg agtattaggg aaaaggagat gaatatgaaa
     1081 tttgggaaac gtcactatcg tccgcaagtg gatcagatgg actgcggtgt agcttcatta
     1141 gccatggttt ttggctacta tggtagttat tattttttgg ctcacttgcg agaattggct
     1201 aagacgacca tggatgggac gacggctttg ggcttggtca aggtggcaga ggagattggc
     1261 tttgagacac gagctatcaa ggcggatatg acgctttttg atttgcccga tttgactttt
     1321 ccttttgttg cccatgtgct taaggaaggg aaattgctcc actactatgt ggtgactggg
     1381 caggataagg acagcattca tattgccgat ccagatcctg gggtgaaatt gaccaaactg
     1441 ccacgtgagc gttttgagga agaatggaca ggagtgactc tgtttatggc acctagtcca
     1501 gactacaagc ctcataagga tcaaaagaat ggtctgctct cttttatccc tatattagtg
     1561 aagcagcgtg gcttgattgc caatatcgtt ttggcaacac tcttggtaac cttgattaac
     1621 attgtgggtt cttattatct gcagtctatc attgatacct atgtgccaga tcagatgcgt
     1681 tcgacgttgg ggattatttc tattgggcta gtcatcgtct acatcctcca gcaaatcttg
     1741 tcttacgctc aggagtatct cttgcttgtt ttggggcaac gcttgtcgat tgacgtgatt
     1801 ttgtcctata tcaagcatgt ttttcacctc cctatgtcct tctttgcgac acgcaggaca
     1861 ggggagatcg tgtctcgttt tacagatgct aacagtatca tcgatgcgct ggcttcgacc
     1921 atcctttcga ttttcctaga tgtgtcaacg gttgtcatta tttcccttgt tttattttca
     1981 caaaatacca atctcttttt catgacttta ttggcgcttc ctatctacac agtgattatc
     2041 tttgccttta tgaagccatt tgaaaagatg aatcgggaca ccatggaagc caatgcggct
     2101 ctgtcttctt ctatcattga ggacatcaat ggtattgaga ctatcaagtc cttgaccagt
     2161 gaaagtcagc gttaccaaaa aattgacaag gaatttgtgg attatctgaa gaaatccttt
     2221 acctatagtc gagcagagag tcagcaaaag gctctgaaaa aggttgccca tctcttgctt
     2281 aatgtcggca ttctctggat gggggctgtt ctggtcatgg atggcaagat gagtttgggg
     2341 cagttgatta cctataatac cttgctggtt tactttacca atcctttgga aaatatcatc
     2401 aatctgcaaa ccaagcttca gacagcgcag gttgccaata accgtctaaa tgaagtgtat
     2461 ctagtagctt ctgagtttga ggagaagaaa acagttgagg atttgagctt gatgaaggga
     2521 gagatgactt tcaagcaggt tcattacaag tatggctatg gtcgagacgt cttgtcggat
     2581 atcaatttaa ccgttcccca agggtctaag gtggcttttg tggggatttc agggtcaggt
     2641 aagacgactt tggccaagat gatggttaat ttttacgacc caagtcaagg ggagattagt
     2701 ctgggtggtg tcaatctcaa tcagattgat aaaaaagccc tgcgccagta catcaactat
     2761 ctgcctcaac agccctatgt ctttaacgga acgattttgg agaatcttct tttgggagcc
     2821 aaggagggga cgacacagga agatatctta cgggcggtcg aattggcaga gattcgagag
     2881 gatatcgagc gcatgccact gaattatcag acagaattga cttcggatgg ggcagggatt
     2941 tcaggtggtc aacgtcagag aatcgctttg gcgcgtgctc tcttgacaga tgcgccggtc
     3001 ttgattttgg atgaggcgac tagcagtttg gatattttga cagagaagcg gattgtcgat
     3061 aatctcatgg ctttggacaa gaccttgatt ttcattgctc accgcttgac tattgctgag
     3121 cggacagaga aggtagttgt cttggatcag ggcaagattg tcgaagaagg aaagcatgct
     3181 gatttgcttg cacagggtgg cttttacgcc catttggtca atagctagaa agaggagagg
     3241 atgaaaccag aatttttaga aagtgcggag ttttataatc gtcgttacca taatttttcc
     3301 agtagtgtga ttgtacccat ggcccttctg ctcgtgtttt tacttggctt tgcaactgtt
     3361 gcagaaaagg agatgagttt gtccactaga gctactgtcg aacctagtcg tatccttgca
     3421 aatatccagt caactagcaa caatcgtatt cttgtcaatc atttggaaga aaataagctg
     3481 gttaagaagg gggatctttt ggttcaatac caagaagggg cagagggtgt ccaagcggag
     3541 tcctatgcca gtcagttgga catgctaaag gatcaaaaaa agcaattgga gtatctgcaa
     3601 aagagcctgc aagaagggga gaaccacttt ccagaggagg ataagtttgg ctaccaagcc
     3661 acctttcgcg actacatcag tcaagcaggc agtcttaggg ctagtacatc gcaacaaaat
     3721 gagaccatcg cgtcccagaa tgcagcagct agccaaaccc aagccgaaat cggcaacctc
     3781 atcagtcaaa cagaggctaa aattcgcgat taccagacag ttaagtcagc tattgaaaca
     3841 ggtgcttcct tggccggtca gaatctagcc tactctcttt accagtccta caagtctcag
     3901 ggcgaggaaa atccccaaac taaggttcag gcagttgcac aggttgaagc acagatttct
     3961 cagttagaat ctagtcttgc tacttaccgt gtccagtatg caggttcagg tacccagcaa
     4021 gcctatgcgt cagggttaag cagtcaattg gaatccctta aatcccaaca cttggcaaag
     4081 gttggtcagg aattgaccct tctagcccag aaaatcttgg aggcagagtc aggtaagaag
     4141 gtacagggaa atcttttaga caaggggaaa attacggcaa gtgagaatgg ggtgcttcat
     4201 cttaatcctg agaccagtga ttctagcatg gttgcagaag gtgccctact agcccaactt
     4261 tatccatctt tggaaagaga agggaaagcc aaactcacag cctatctaag ttcaaaagat
     4321 gtagcaagaa tcaaggtcgg tgattctgtt cgctatacta cgactcatga tgccgggaat
     4381 caactttttc tagattctac tattacaagt attgatgcga cagctactaa gactgagaaa
     4441 gggaatttct ttaaaatcga ggcggagatt aatctaactt cggagcaggc tgaaaaactt
     4501 aggtacgggg tggaaggccg tctacagatg attacgggca agaaaagtta tctacgttat
     4561 tatttggatc aatttttgaa caaagagtaa tgttcgtgtt tttagagtta aataattttt
     4621 aaactgtgag aaagattctt cttgcagttt tttctttaca atttttgaaa aacatctgct
     4681 atttattcgg ttaaattctt gtgttttttg attttttgtg gtaaaatgtg ctcaagtaat
     4741 acgaaaggcg aactttaaaa tgtcaaaaca attgatctat tcgggaaaag ctaaagatat
     4801 ctatacaact gaggatgaaa atcttattat ttcaacttac aaggaccagg cgactgcttt
     4861 caacggtgtc aagaaggagc agattgcagg taagggagtc ttgaataatc agatctcatc
     4921 ttttattttt gagaaattaa atgcggctgg tgtggcgact cactttgtgg agaaactttc
     4981 agacacggaa caactcaata aaaaggttaa gattattcct ttggaagtcg tgctccgcaa
     5041 ctatactgct ggttcctttt caaaacgttt tggtgtggat gagggaatcg ccttggagac
     5101 tccgattgtc gaattttact acaaaaatga tgatttggat gatccattta tcaatgatga
     5161 gcatgtgaaa ttcctacaga ttgcggatga ccagcagatt gcctacttga aggaagaaac
     5221 gcgtcgtatc aatgaactat tgaaagtctg gtttgctgag attgggctta aattgattga
     5281 ctttaagcta gagttcggtt ttgacaagga cggcaagatt atcttggcag acgaattttc
     5341 accagataac tgccgcttgt gggatgctga tggcaaccac atggataagg atgttttccg
     5401 tagaggattg ggagaactaa ccgacgttta tgagattgtt tgggaaaagt tgcaggaatt
     5461 gaaataatct gtttgcaatg gaaaaccttc gtctctcaac taaaaggact caggctgaaa
     5521 aggtccccca gaccttttca ctctgtagag aactaggtga actaaccgat gtttacgaaa
     5581 ttgtctggga aaagttgtag ggtttaaaat aacaacctca aggctgttta ggaatattgc
     5641 aagagctgaa ataaaggaat aagaattgat ggataaacgt atttttgttg aaaaaaaggc
     5701 tgattttcag gtcaagtcag agagtttggt tagagagctc cagtacaact tgggactgtc
     5761 aagcttgaaa agtattcgta ttgtgcaagt atatgatgta tttgacttgg ttgaggactt
     5821 gtttgcacct gcagagaagc acattttctc tgagcaggta accgaccatg ttttagatga
     5881 agtatctgtg caggcggatc ttgctaacta tgctttcttt gccattgaaa gtctgccagg
     5941 gcagtttgac cagcgtgcag cttcgtcaca ggaagccttg cttttgttgg gaagttcgag
     6001 tgacgtgaca gtcaacacag cccaacttta cttggtgaat aaagatattg atgcgactga
     6061 gttggaagct gtcaaaaact acctgctcaa tccagttgat tctcgtttca aggatatcac
     6121 gacagggatt gctaagcagg agttttcaga gtcagacaag accattccaa aattgacttt
     6181 ctttgaaagc tatacggcag aagactttgc tcgctacaag gacgagcaag ggatggccat
     6241 ggaagtggat gatttgctct ttatccaaga ctactttaag tcaatcgggc gcgtgccaac
     6301 tgagactgaa ttcaaggttt tggacactta ctggtctgat cactgccgtc atacgacttt
     6361 tgagacagag ttgaaacaca tcgacttttc agcttctaaa tttcaaaagc aattgcagtc
     6421 aacctatgac aagtatattg tcatgcgcga ggaattaggt cggtctgaaa aaccacaaac
     6481 cttgatggat atggcgacta ttttcggtcg ttatgagcgt gctaatggac gattggatga
     6541 tatggaagtc tctgacgaaa tcaatgcctg ctcagttgaa attgaagtgg acgttgatgg
     6601 tgtcaaggaa ccttggctcc tcatgtttaa aaacgaaacc cacaaccatc caacagaaat
     6661 tgagccattt ggtggagcgg ctacctgtat cggtggagct attcgtgatc cgttgtcagg
     6721 ccgttcctat gtttaccaag ccatgcgtat ttcaggtgct ggtgatatta cagcaccgat
     6781 ttcggaaact cgcgctggga aattgccaca acaagtcatt tctaaaacag cagctcatgg
     6841 ttattcttca tatggtaacc agattgggct tgcaacaacc tacgttcgtg aatacttcca
     6901 cccaggcttt gtagctaaac gtatggaact tggtgccgtt gttggtgcgg ctcccaaggg
     6961 caatgttgtc cgtgaaaaac ctgaagcagg tgatgtgatc atccttctcg gaggcaaaac
     7021 aggtcgtgat ggtgtcggtg gtgcgacggg ctcttctaag gttcaaacag ttgagtctgt
     7081 agagactgct ggtgctgagg ttcaaaaagg aaatgccatc gaagaacgca agattcagcg
     7141 cctcttccgt aatggcaatg tcactcgtct gatcaagaag tccaatgact ttggggcagg
     7201 cggcgtctgt gtggctatcg gtgaattggc agacggtctt gaaatcgacc tcaacaaggt
     7261 gcctcttaaa taccagggct tgaatggtac agaaattgcc atctctgaat cacaagaacg
     7321 gatggcggtc gtggttcgtc ctgaagatgt ggatgccttc gttgccgaat gtaacaaaga
     7381 aaatattgat gctgttgtgg tggcgacagt aactgaaaaa ccaaatcttg tcatgcactg
     7441 gaatggtgag acaatcgttg acttggagcg tcgtttcctt gacaccaatg gtgtgcgcgt
     7501 ggttgtcgat gccaaagttg tggacaagga tgtcaaactc ccagaagagc gtcaaacatc
     7561 tgctgaaaca ctggaatcag atacccttac ggttctatct gacctcaacc atgcaagtca
     7621 aaaaggatta cagactatct ttgactgctc tgttggacgc tcaacggtta atcacccact
     7681 tggtggtcgt taccaactca caccaactga ggcatctgtg cagaaattgc cagttcaaca
     7741 cggtgtgact catactgcgt cggtcattgc tcaaggtttc aacccatatg tagctgaatg
     7801 gtctccatac cacggtgctg cttatgcggt tatcgaagca actgctcgtt tggtggctgc
     7861 tggtgccaac tggtctaagg ctcgtttctc ttaccaagaa tatttcgagc ggatggacaa
     7921 gcaagcagag cgtttcggtc agccagtagc tgctcttcta ggttctattg aagcacaaat
     7981 tcagcttggc ttgccatcta tcggtggtaa ggactccatg tctggtacct ttgaagaatt
     8041 gaccgttccg ccaaccttgg ttgcctttgg ggtgacgacg gcagatagcc gtaaggtgct
     8101 ctctccagaa tttaaagctg ttggggaaaa tatctactac atcccaggtc aagccctctc
     8161 tgcagagatt gattttgact tgattaagaa aaattttgct cagtttgaag caagccaagc
     8221 tgaccataaa gtgacgtctg catcagctgt caaatacggt ggtgtagttg aaagtttggc
     8281 tcttgctacc tttggaaact atattggtgc agaggtgacc ttgcctgaac ttaaaacagc
     8341 tttgacagct caattaggcg gctttgtctt cacatctcct gaagaaattg ctggagtaga
     8401 gaagattgga caaacgaaag cagactttac actgactgtc aacggtgtga agctagatgg
     8461 acacaagctt gacagtgcat ttcaagggac attggaagaa gtttacccaa cagaatttac
     8521 ccaagcgaaa gaactagaag aagtaccagc tgtggcatca gatgttgtga ttaaagccaa
     8581 agaaaaggtt gaaaaacctg tggtttacat cccagtcttt ccaggaacca actcagaata
     8641 tgattcagct aaggccttcg aaaaagaagg tgcagaggtc aatttggtgc cattcgtgac
     8701 cttgaatgaa gaagctattg tcaagtcagt tgaaactatg gttgacaata tcgacaagac
     8761 taatattctc ttctttgccg gtggattctc ggctgcggat gaaccagatg gttcagctaa
     8821 gtttatcgtc aatatcctgc ttaatgaaaa agtgcgtgtg gctattgata gctttatcgc
     8881 ccgtggtggc ttgattatcg gtatttgtaa tggattccaa gccttagtca aatcgggtct
     8941 cctaccatac ggaaactttg aagatgctaa cagtactagt ccaaccctct tctacaatga
     9001 tgccaaccaa cacgtggcca agatggtgga aactcgtatt gccaatacca actcaccatg
     9061 gttggctggt gtgcaagtgg gcgatatcca cgctattcct gtttcgcacg gtgaagggaa
     9121 gtttgtcgtg acggctgagg aatttgcaga gctccgtgac aatggacaaa ttttcagcca
     9181 atacgttgac tttaacggta aaccaagtat ggattctaag tacaatccga atggttctgt
     9241 ccatgccatc gaaggaatta ccagcaagaa tggtcaaatc atcggtaaga tgggccactc
     9301 agaacgttat gaggatggtc ttttccaaaa tatcccaggc aataaagacc agcacctgtt
     9361 cgcgtcagcg gttaaacatt tcactggaaa ataagactta cagattttct aatagatagt
     9421 atcagtaatg taaaagtcat gtaaatctag ctcttgatga ttacaaatga aaattaggta
     9481 taaaaaatga catacgaagt aaaatctctt aatgaagaat gtggtgtttt cggtatttgg
     9541 ggacatccag atgctgctaa gttgacctat tttggactcc acagtcttca acaccgtggt
     9601 caggaggggg caggaatcct ctccaatgat caaggacaac tgaagcgcca tcgtgacatg
     9661 gggcttttat cagaagtttt cagaaatcca gctaatttgg ataaattgac aggagctggt
     9721 gcgattgggc atgtgcgtta tgcgactgct ggcgaagctt ctgtagataa catccagccc
     9781 ttcctcttcc gttttcacga tatgcagttt ggcttggctc ataatggaaa tctgaccaat
     9841 gcagcctctc tcaagaaaga actggaacaa agaggagcaa ttttcagcgc gacttcggac
     9901 tctgaaatct tggctcacct cattcgtcgc agtcataatc ctagcctgat gggcaaaatc
     9961 aaggaagcgc tcagccttgt caaaggtggt tttgcctata tcttgctgtt tgaggacaag
    10021 ttgattgcgg ctcttgaccc taatggcttt cgtccgcttt ctatcgggaa aatggccaac
    10081 ggagcggtgg ttgtttcctc tgaaacctgt gcttttgagg tcattggtgc cgagtggatt
    10141 cgtgatttga agccaggtga gattgtgatc attgatgacg agggcattca gtatgacagc
    10201 tatacagatg atacccagtt ggcgatttgt tctatggagt atatctactt tgcccgccct
    10261 gattctaata tccacggtgt caatgtccat acggcacgta agagaatggg agcgcaattg
    10321 gcgcgagaat ttaagcatga ggcagatatt gtagttggtg tgcccaattc ttccctaagc
    10381 gcggctatgg gatttgcgga agaatcaggc ttaccaaatg aaatgggtct gatcaaaaac
    10441 caatacaccc agcgaacttt tatccaaccg actcaagaat tgcgggagca aggagtgcgg
    10501 atgaaactgt ctgctgtttc gggtgttgtc aaaggcaaac gtgtggtcat ggtggatgat
    10561 tccattgtac gtggaacaac ctctcgtcgt atcgttcagc tcttgaaaga agcgggtgcg
    10621 actgaggttc acgttgccat tggaagtcct gcactagcgt atccatgttt ctacgggatt
    10681 gatatccaga cccgtcagga gctgattgca gccaatcata cggtcgaaga aactcgccaa
    10741 atcattggtg cggacagtct gacttatctt tcaattgatg gcttgattga gtcgattggt
    10801 atcgaaacag atgcgccgaa cggtggtctc tgtgtcgctt actttgacgg tgactaccca
    10861 acgcctctct atgactacga agaagactat cgtagaagtt tggaagaaaa gaccagtttt
    10921 tacaagtagg cgacagattc tccattaaag aaaaggaaaa aacaaatgac aaataaaaat
    10981 gcatatgccc agtcgggtgt ggatgttgaa gcgggttatg aagttgttga acggattaaa
    11041 aagcacgtgg cccgtacgga gcgtgcaggt gtcatgggag ctcttggtgg ctttggtggt
    11101 atgtttgacc tttccaagac tggggttaaa gaacccgtct tgatttcagg gactgacggt
    11161 gtcggaacca agctcatgtt ggctatcaag tacgacaagc acgataccat cgggcaggac
    11221 tgtgtggcca tgtgtgtcaa cgacatcatt gctgcaggtg cggaacccct ctattttctc
    11281 gactacgtag cgacagggaa gaatgaacca gctaagctag aacaagtggt tgctggtgtg
    11341 gcagaaggtt gtgtgcaggc tggtgctgcc ctcatcggtg gggaaacggc tgaaatgccg
    11401 ggcatgtacg gcgaagacga ctatgacttg gctggttttg cggtcggtgt ggctgaaaaa
    11461 tctcaaatca ttgacggttc aaaggtggta gagggagatg ttcttctcgg acttgtttca
    11521 agtgggattc actcaaatgg ttactctttg gttcgtcgtg tctttgcgga ttacacaggt
    11581 gaggaagtcc taccagaatt ggaaggcaag aaacttaagg aagttctact tgagccgact
    11641 cgtatctatg tcaaggctgt cttgccgctc atcaaagaag agttggtcaa cggcattgcc
    11701 cacatcacag gtggtggctt tatcgaaaat gtccctcgta tgtttgcaga tgacctagct
    11761 gctgaaattg atgaaagcaa agttccagtg cttccaattt tcaaagccct tgaaaaatat
    11821 ggtcagatta aacacgaaga aatgtttgaa atcttcaata tgggtgtggg acttatgttg
    11881 gcggtcagcc ctgaaaatgt agagcgtgta aaagaattgt tggatgaagc agtctatgaa
    11941 attggtcgca tcgtcaagaa agaaaacgaa agtgtcatta tcaaatgaaa aaaatagcgg
    12001 tttttgcctc tggtaatggc tcaaattttc aggtgattgc cgaagaattt ccagtggagt
    12061 ttgtcttttc agaccatcgt gatgcctatg tgcttgagcg tgcaaagcag ctcggcgttc
    12121 tgtcctatgc ttttgaactc aaggagtttg agagcaagac agactacgaa gcagcccttg
    12181 tcgaactctt ggaagaacac cagattgact tggtttgcct agcaggctac atgaaaatcg
    12241 ttggaccaac cttattgtcg gcttatgaag gtcggattgt caacattcat ccagcctact
    12301 tgccagaatt tccaggagct catgggattg aggatgcttg gaatgctggc gtgggtcagt
    12361 ctggtgtgac cattcactgg gtggattcgg gtgtggatac aggccaggtc atcaaacagg
    12421 ttcgtgtgcc acgactagct gatgatacca ttgacagatt tgaagctcgc atccatgaag
    12481 cagagtacag gttgtatccg gaagtagtga aggctctatt tacagattga ctttttgatg
    12541 attcatatga tatctttgat tttaaattgg agtcagtgtt tgttgaagac ggcttcaaac
    12601 ggaggtattt gtaatgttag aatctaaaaa aacaactcga tatgtatttt atgtctatct
    12661 gatgttatta acttggggaa tcttatttaa gtttgaaaca aatcctgaat ttatagcatt
    12721 tttcttagct ccaaggtata tcaattggat tccattttca gaaccactaa tagtcgatgg
    12781 aaaaattgtt tttgctgaaa tgttatttaa tctgatttcc tttattccat taggtgtttg
    12841 tttccctttg ataaaaacta atttatctag tttaagaata gtcgggacag gtttcttgat
    12901 tagtttattg tttgagtgct tacagtatat tttagcaata ggtataacag atataacgga
    12961 tttgacttta aatacgctag gtgtctgtgt aggcttactg atttatcaaa tttttataag
    13021 agtgttcaaa tcacagacta gaaaatggat caatatctta ggtatgctta gccttggttt
    13081 tgcttatctt gttttactgt tactgcattt aattggtgtt taactaatga ttaaaaagga
    13141 gaatataatg actaaacgcg tcttaatcag cgtctcagac aaagcgggca ttgttgaatt
    13201 tgcccaagaa ctaaaaaaac ttggttggga gattatctcg acaggtggaa ctaaggttgc
    13261 ccttgataat gctggggtgg agaccattgc gatcgatgat gtgacgggct tcccagagat
    13321 gatggatggc cgtgttaaga ctcttcatcc aaatatccac gggggtcttc tcgctcgtcg
    13381 tgatttggat agccacttgg aagcagccaa tgagaaccaa attgagctta ttgaccttgt
    13441 agtggtcaac ctttatcctt tcaaggaaac gattctcaaa ccagacgtga cgtacgctga
    13501 tgctgtggag aatattgata ttggtgggcc atctatgctt cgttcagcag cgaagaatca
    13561 tgccagcgtg acggttgtgg tagaccctgc tgactataca gtggttttgg acgagttgtc
    13621 agccaatggt gaaacgactt acgaaacgcg tcaacgtttg gcagccaagg ttttccgtca
    13681 cacagcggct tatgacgctt tgattgcaga atacttcaca gctcaagtgg gcgaaagcaa
    13741 acctgaaaag ttgaccttga cctatgacct aaaacaagct atgcgttatg gggaaaatcc
    13801 ccagcaggat gcggacttct accagaaagc tttgccgact gattactcca ttgcatcagc
    13861 caaacagctt aacggtaagg aattgtcatt caacaatatc cgcgatgcag atgctgccat
    13921 tcgtattatc cgtgacttca aagaccgtcc aaccgttgtg gctctcaagc atatgaatcc
    13981 atgtggtatc ggccaggcgg atgacatcga gacggcttgg gattatgctt atgagtctga
    14041 cccagtgtct atctttggtg gtatcgctgt tcttaaccgt gaggtggatg ctgcgacagc
    14101 tgagaagatg cacggcgttt tcctcgaaat catcattgca ccaagctata cggatgaagc
    14161 gctagccatt ttgatcaata aaaagaaaaa cttgcgtatc cttgccttgc catttaatgc
    14221 tcaagaggct agcgaagtgg aagcagaata cacaggtgta gtcggtggac ttctcgtgca
    14281 aaatcaagac gtggtcaagg aaagcccagc tgactggcaa gtggtgacca aacgtcagcc
    14341 aaccgagaca gaagcgactg ctcttgagtt cgcttggaag gctatcaagt acgtcaaatc
    14401 aaatggtatt atcgtgacca acgaccacat gacacttggt gttggtccag gtcaaaccaa
    14461 ccgtgtggct tctgttcgcc ttgccattga ccaagccaaa gatcgtctgg acggggcggt
    14521 ccttgcttca gatgccttct tcccatttgc ggataacgtg gaagaaatcg ccaaagcagg
    14581 aattaaggcc atcatccagc ccggtggctc tgtccgtgac caagaatcca tcgaagcagc
    14641 ggataaatac ggcttgacta tggtctttac aggtgtgaga cattttagac attaagaaga
    14701 taaaagggaa gaaaacagtt tctttccttt tttggcttaa aatgctaact gaaacaagat
    14761 taaaacgaac ttttttgata taatgttggt aaataattcg caaaagaggt tgaggaatga
    14821 aactgcttgt tgtcggttct ggtggtcgtg agcatgcgat tgctaaaaag ttacttgaat
    14881 caaaagacgt ggaaaaagtc tttgtagctc ctgggaatga tgggatgact ctggatggtt
    14941 tggaattggt aaatatctct atttccgaac attctaaatt gattgacttc gcaaagacca
    15001 atgatgttgc ttggaccttt atcggtccag atgatgccct tgctgctggt atcgtggatg
    15061 attttaacca agctggactt aaggcctttg gtccgactag ggctgcagcg gagctggagt
    15121 ggtccaagga tttcgccaag gaaatcatgg tcaaatacgg cgttccgaca gcaacatatg
    15181 gcacattttc agatttcgag gaagccaagg cctatatcga aaagcatggt gcgcctatcg
    15241 tagtcaaggc ggatggcttg gcacttggga agggtgtcgt cgttgctgag acggttgagc
    15301 aagcggtcga agccgctcat gagatgcttt tggacaataa atttggtgac tcaggtgcgc
    15361 gcgtggttat tgaggaattc cttgaaggag aggaattttc actctttgcc tttgtcaatg
    15421 gtgataagtt ctacatcatg ccaacggctc aggaccacaa acgtgcctat gatggcgaca
    15481 aagggcctaa cacgggtggt atgggtgcct atgcgccagt cccacactta ccacagagtg
    15541 tagttgatac agcggttgac accattgtca agccagttct agaaggggtg attaaagaag
    15601 gtcgccctta tctgggagtt ctttacgcag ggcttatcct gacagctgat ggaccgaaag
    15661 tcattgagtt caacgctcgg ttcggagatc cagaaactca gattatcttg cctcgcttga
    15721 cctctgactt tgctcaaaat atcacagata tcctggatag caaggagcca aatatcatgt
    15781 ggacggacaa gggtgtgact ctgggtgtgg ttgtcgcatc caagggctac ccgctagact
    15841 atgaaagggg cgttgagttg ccagcaaaga cagaaggcga tgtcatcacc tactatgcag
    15901 gggctaagtt tgcggaaaat agcagagcac tgctctcaaa cggcggacga gtttatatgc
    15961 tcgttaccac agcagatacc gtcaaagaag cccaagccag catctaccaa gaactatccc
    16021 aacaaaaaat agaaggactc ttctaccgaa cagatatcgg aagcaaggca attaagtaaa
    16081 gatataagaa taacgcgccg tagtcgccaa acacgataat ggtcgtcgtg gtgaaaagac
    16141 cagaacagtg aatgttctgg tcagggggaa acttggagac cttaggctca aagtttagga
    16201 atgaaaccga aggtttgctt ccgcctccat cacctaagac cattatcaaa aagaaaaata
    16261 aaaattcaca aaatacgtta atgatcgtat ggtttgcgag cgttagcgag ctaatataga
    16321 acaatcaccg ccgttgtgaa agaacgattg gatgataatc caatcgttca gggaaattgg
    16381 aagaccttgg gtttccaatt taggcatgag acacctttgg tggctgctgc cgtccctcac
    16441 aagctaaggt gattgttgaa aaagaggaaa aaggagaaga aatgaaacca gtaatttcca
    16501 tcatcatggg ctcaaaatcc gactgggcaa ccatgcaaaa aacagcagaa gtcctagacc
    16561 gcttcggtgt agcctacgaa aagaaagttg tttccgcaca ccgtacacca gacctcatgt
    16621 tcaaacatgc agaagaagcc cgtagtcgtg gcatcaagat catcatcgca ggtgctggtg
    16681 gcgcagcgca tttgccaggc atggtagctg ccaaaacaac ccttccagtc attggtgtgc
    16741 cagtcaagtc tcgtgctctt agtggagtgg attcactcta ttctatcgtt cagatgccgg
    16801 gtggggtgcc tgttgcgacc atggctatcg gtgaagctgg agcgactaac gcagctctct
    16861 ttgccctccg tctcctctct gtagaagata agtccattgc ggatgcactt gccaactttg
    16921 ctgaagaaca aggaaaaatc gcagaggagt cgtcaaatga gctcatctaa aacaatcgga
    16981 attatcggtg gcggtcaact gggtcagatg atggccattt ctgctatcta catgggccac
    17041 aaggttatcg cgctggatcc tgcggcggat tgcccggcct ctcgcgtggc ggaaatcatt
    17101 gtggcacctt ataacgatgt ggacgccctc cgtcagttgg cagaccgttg cgatgtcctc
    17161 acttatgagt ttgaaaatgt cgacgctgac ggtttggatg ccgttatcaa ggatggacaa
    17221 ctccctcaag gaacagatct gctccgcatt tcgcaaaatc gtatttttga aaaggacttt
    17281 ttgtcaaaca aggctcaagt cactgtggca ccctacaagg tcgtgacttc tagcctagac
    17341 ttggcagata tcgacttgtc gaaaaactat gtcctcaaga ctgcgactgg tggctacgat
    17401 ggtcatggac aaaaggttat tcgttcagaa gcagacttgg aagcagccta tgcgctagca
    17461 gactcagcag actgcgtctt ggaagaattt gtcaactttg accttgagat ttctgtcatc
    17521 gtgtcaggaa atggcaagga ggtgacgttt ttcccagttc aggaaaatat ccaccgcaac
    17581 aatatcctgt ctaagaccat cgtaccagcc cgcatttctg aaagtctagt agacaaggct
    17641 aaagctatgg cagtgcgaat cgcagaacaa ctcaacttgt ctggaactct ctgtgtggaa
    17701 atgtttgcga ctgatgatga cgttattgtc aatgaaatcg ccccacgacc acataactct
    17761 gggcactatt ctattgaagc ctgtgatttc tctcagtttg acacccatat tctcggtgtt
    17821 ctcggagcac cattaccagt catcaaactc catgcgccag ccgttatgct taatgtcctc
    17881 ggtcagcatg tcgaggctgc tgagcaatat gtgacagaaa attcaagcgc ccacctccac
    17941 atgtatggta aaatagaagc gaagcacaac cgcaagatgg gacatgtgac cttgtttagt
    18001 gatgtaccgg atagtgtgga tgagcttggg gaagggattg atttttagga caagtctatg
    18061 atacaaatta tcgttaatac atttattgaa aaggatagga ctggagcagt tgttgaagtg
    18121 ttgtatgcca gtgctgacca agataaggta caagctaaat atgaagaact agctgcacaa
    18181 taccccgaaa attatttagc tatctatgat gtaccgctgg atacggattt gaatacacta
    18241 gatcattacc cgtctgtgtt tattgaaaaa gaggagtttg agtagaaatc ttggtttacc
    18301 tagatagctt attcccaaca gcttaagaag aaaggaaaaa ttaacacatg atcaaccgtt
    18361 actctcgccc tgagatggcg aatatttgga gtgaagaaaa taaataccgt gcttggcttg
    18421 aggtggaaat cctctctgac gaggcatggg ctgagttggg ggaaatccct aaggaagatg
    18481 tggctttgat tcgcaagaag gcggactttg acatcgaccg tattttggaa attgagcagg
    18541 agacgcgcca cgatgtggtg gctttcacgc gtgcggtttc tgagactctt ggtgaagagc
    18601 gcaagtgggt tcactatggg ttaacttcta ccgacgtggt ggatactgct tatggttacc
    18661 tctacaagca ggccaacgac atcatccgtc gtgaccttga aaacttcact aatatcatcg
    18721 ctgacaaggc caaggagcac aagttcacca tcatgatggg gcgtactcat ggtgtgcacg
    18781 ctgagccgac aacctttggt cttaaattgg caacttggta cagcgaaatg aaacgcaata
    18841 tcgagcgttt cgagcatgca gctgctggtg tagaagctgg taagatttct ggtgcggttg
    18901 ggaactttgc caatatccca ccatttgtag aggagtatgt ctgcgataaa cttggcatcc
    18961 gtgcccaaga aatctctaca caagtccttc ctcgtgacct tcacgctgag tactttgcgg
    19021 ttcttgccag cattgcgact tcaatcgaac gtatggcgac tgagattcgt ggtctacaaa
    19081 aatctgagca acgcgaagta gaagagttct ttgctaaagg gcaaaaagga tcttcagcaa
    19141 tgcctcacaa acgcaaccca atcggttctg aaaatatgac tggtctggcg cgtgtcattc
    19201 gtggtcacat gattacggct tatgaaaacg tcgctctctg gcacgaacgc gatatttccc
    19261 actcatcagc tgagcgtatc atcacaccag atacgaccat tttgattgac tacatgctca
    19321 accgttttgg aaatatcgtc aagaacttga cagtcttccc agaaaatatg atccgaaaca
    19381 tgaactcgac ttttggtctt atctttagcc aacgggctat gttgacattg attgaaaaag
    19441 gcatgacccg tgagcaagcc tatgacttgg tgcaaccaaa aacagcctac tcttgggaca
    19501 accaagtaga ctttaaacca cttcttgagg cagattcaga agtaacatca cgtctcactc
    19561 aagaagaaat cgatgaaatc ttcaacccag tttattacac caaacgagtg gatgatatct
    19621 ttgaacgtct tggactaggt gattaattaa aaaataaaca gcgagcttca atctcgctgt
    19681 ttatttttta tcgaaaagac ttagtcttct tttcttttag tgagtccata ggctgctagt
    19741 gtggccatga gtcctgcgac tactagtcct gcagaatcgt gagttcctgt ttcaggaagt
    19801 tttttctcta ttaccacagg agctggatct tgaggaagag ctttgctttc ctcagcagga
    19861 gcagttgatg gagctggttg gcttgggatt tctagttttg gtttttcttc agcaatagcg
    19921 gcttgtccgt tttcatcgcc tacatgtgtt accatagttc cgacttcgac tatttgagta
    19981 acggcttcct gtgctacgac actatttaca agtgttttca cttccttacc atcggcagaa
    20041 gtgctcacag agtagaagtt gctacgatgt ccattgacgc ccttagtaat gacttgtgtt
    20101 tttcctttga gtaagagtgg attttcacga gtcactgtgg taaatggaat ttcttcttct
    20161 tggatatcca gtctaggttt tacctcagta gttggtgcaa gaccactttc atcacccttg
    20221 tgagttacag gagcgccaac ttcaaccact tggtttataa cttctttggt tacctggcta
    20281 tcaaggactg tttctgttgt ttttccattt tcagtgagta cagagatgta atgagttcgt
    20341 tcacctttga ctcctgctgt gataatattt tcctgaccag ctgggaggtt aggattttct
    20401 ttcttgataa cttcaaatgg aatttcttca gttcttgtga tgagttctgg tctggtttca
    20461 acattggcag ccacttcatt ttcatccagg cttcctgaat gagttgcagc tggtttgagg
    20521 ccttgaagag cggcttttag gttggctaca agtgtgtcaa gctcagcttg tttattacgg
    20581 ttgaggttgt aatttagagc tgttttagct gcgtcaaggg cctcaagact ttctttacta
    20641 tatccttcta agtttgtagg aattttagct aattcttcgc ggagagcatt ataattagca
    20701 cggaagtagt ctttgttgtg gtctgcaaag gcagtcatga gttcaaagat ttcctcttcc
    20761 ttgtactcag cgcttggtct atctgcccag attgaaagca tacttccgac tgttggaaga
    20821 tctacttcag gatatttggt agaagctagt tgattgaatg gtgtttttcc agtattctca
    20881 atagctttct tgaggaaacc accaccatct tctggttttt gaccaagaat gtagtaccag
    20941 tcaccgttgg tattcaagaa tttatagcct ttgcttgcta ggtattgagg tgatgcgagg
    21001 ttatatcccc accagccttt agaccagtaa gaaatcaaga catctttgtc aaactgaaca
    21061 tcgtccttgt cttcatagta gaagccatcg ttgaaggcca ttggttgaag ccctctttct
    21121 ttggccatag ctgcgagggt gttggcatat tcggcaaatt tgccatagag ttgataccac
    21181 ttgaggtagt accagccttg ggcactagtc gcatcgttgg cgtattcgtc agtaccaaag
    21241 ttgaaaatct ttgttttacc tgcaaagaag tccatgtatt taccgatgag ggcttttaca
    21301 aagttcatcg cttcttcgtt tttcaagtcc atagttgttt ttgaaacttt atcaaagtgg
    21361 gcttgaggat ttttaatacc taatttttcc atggcaacca gcatagcatc catgtgacct
    21421 ggactgttaa tagctgggat gagaccgatg tccttagatt tagcgtattc aattagctct
    21481 gtcacttctg cctgtgttag tgtagtaccg tttggatcgt cgtagtaagc tttagttcct
    21541 tcgataatag cttttttaac gtcatcacta gcataggttt ttccgttggc agtaatggtc
    21601 atatcatcga gtagaaagcg aagtccgtca tttcctagaa ggagatggac atcagaatat
    21661 ccgagttcac tggccttgtc tacgatgcgt ttgagctggt tcagagtaaa gtatttgcgt
    21721 ccagcatcga ttgagattac cttgtttttg gcaagttttt caacctcacg tttagcttct
    21781 tcttcttttt gagcttcagg cgtgagggtc aagttgttga cagtttcttg aagtttagca
    21841 atggcttgat caatcgtatc ttgttgggca cggctaaggt tgctatcgag agagcgaata
    21901 gctttttcag cttcttttac ggccgcgacg ctttctgcag tataacggtt caggtctttt
    21961 ggtacctcgt taagtgcttg ctctgcagat tcataatcag ctgcgaagta ttcagcgttg
    22021 gcatttgcaa aatgacgcat gagtttgaag aggcgtgatg gtgaataacg tgcagatgga
    22081 gtgtcagccc aagcagctac cataccaccg atgattggga tatcagctcc ttctgttttt
    22141 ggtacagaag tgattggtgt gtttttaata ccattgagcc cctgatcgag attgtaccag
    22201 ccttggccat cagcgtttcg tccaagaacg tagtaccaag catcattggt attaaggatt
    22261 tggtgacctt tttcagctag tagtttagaa gaagcgacat cgtagcctcc ccaaccacca
    22321 gtccacatag aaacgatgat gtctttgtca aaactaccaa agcttgtgtc gctattgtag
    22381 tagataccgt cgttaaaggc cattggtttg agaccgtgcg attttacaat acgagcgagg
    22441 tcattggcgt aggcaataaa tttttcatag ccttttacag ggtagccttc gtttggatag
    22501 tatttatcag cttgaagcac actccaacct ttagcatctg tcgcatcatt ggcatattca
    22561 tcaagtccga tgttgaagat ttcagtcttt ttcgcgaaat aagcagcata cttgtcgata
    22621 agggcttttg taaaagcgac agcttgttcg ttgtcaagat tgacagtacg ggctgattcc
    22681 ttcccaaaat agctaaagtt agggttttgg attcccaatt ctttcatggc attgagaatc
    22741 gcatccatgt gaccaggact atttactgtc ggaatgagac cgataccttt atctttggca
    22801 tagttaatca gatctgtcat ttgactttct gttaagtgat tgccgtttgg atcgttgtaa
    22861 taatcatttg tacctttttc aatggcgcgt ttgacatcgt cactggcata ggtcttgccg
    22921 ttagctgtga tgctcatatc gtccaacatg aaacggagtc catcatttcc gactaatagg
    22981 tgtaaatcag tgtagccata atgtttcgct ttatcgatga tttccttgag ctgttctggt
    23041 gagaaatatt tacgtccagc atcaatagaa acaattttct ttttcgctag tttttcattt
    23101 acagttgcag cacgttcctt tcctgcctct gtttccggtt tgtcagcctc tgctttcgct
    23161 tcatcttttt tagctggttt atccttgtca gtcttgtctg tatttgactc tttagaatca
    23221 acctctttcg cttcttcctt tttagggcta gcttcttctg cctttttatt agcagtttct
    23281 ttttcagcag aagttggagt taccacctct gctttatcac taggagttga actaacttcc
    23341 tcttgtggtt tttcttctgt ttttggaaga ctagctacct tatcagtagc tggagtttct
    23401 ggttgaagct ctgctttagg tgtttcctca gtccgatttt cggatgattg aggggaatca
    23461 gaaactgtat ggatggtcgg ttggttttct gtagtagtag taactccatc ggctgcaaca
    23521 gtctgtgctt ggaaggcaaa tccaattaga acagaagctg ctcctacagc gtatttacga
    23581 atagaaaaac gctgttgttt ttcatgtttc attgcaaaac ctcctgattg cattgttata
    23641 ttgatagcga ttatataaat caacgccctt attttatttc ttatattaac gagagtcaag
    23701 aggagatgac aaaaaactat aataagtata aaaaaatata aaatttaaac ttaagatttc
    23761 agattggtcg gaaaaaatgc atatatatat ctaatataat ttttggttct atttctataa
    23821 aatattccac aaattataga atcttccaaa aataggtaag cgctaccttt ttggtgtggt
    23881 ataataagca tagaaaaagc ccgagcgatt aggctcaggc tttcttctta gtgatcatgg
    23941 tcacatgaga tgaatttaat cttgtagtaa tcagatcgtt tgtaagtttc actgtattct
    24001 aaaacttggc cagttgattc gagtttggtg attttagttt gtaggacagt agggaaatgt
    24061 tcatcgactc cgaggactga agccgcatgt tctggagttg gaaagactat ttcgttgatt
    24121 tcttcaaagt gttcatcatt catgtgaatg tggtagtcta acttgaaacg attatagata
    24181 gaactatagt attcaaggtt tggataattt gcgttgatat attgttctgg gatgtaggat
    24241 gtatggtaga tataaacgac accgtttgat tcgcggatac gttcaatctt gtagtagaat
    24301 tgatcgccgc gtagacccaa tttttccaag taaacaagct tgtttccgcg ttcaattgaa
    24361 agaacagtta ccttatcatc tttagcattg aagagttcaa tatctgaaaa ctctacaagc
    24421 ttgtgtttgc gtgcacgtga aacgaaggtt ccttttcctt gttggcggac aatatagcca
    24481 tctttggcaa ggtcgtttaa ggcgcgaaca actgtgatag agctgacatc gtacattgaa
    24541 atgagttctg cttcagtgta aaatttatct ccactgctaa actgcccaga gatgatttta
    24601 ttttttaatt cgtcttttat gtattgatat ttgggaattg ccatattttt acctctattt
    24661 tccttctcca tagaaaattt taccataaaa gcgaaaaaaa tagtagtctt ttgaataaaa
    24721 aattagaata atagtttgaa aaattaagcg atatagggat tgctcatatt ttatcaatgt
    24781 attctataca aaattatttt aggtcctata ttccgaattt aaagagcgtt tgaaatgggt
    24841 ctaaaaatgt ttgaaactaa ttgaatgtgt gtataatagt aaaaatgcag taaatatccc
    24901 gacaatttct attgacaatt caaacagatt ggtttataat taatataaca acaagtgaaa
    24961 gcgcaaactt tcgcggtcgg aaggtagttt tatgacacga tttgagatac gagatgattt
    25021 ctatctcgat ggaaaatcat ttaagatttt atctggtgcc attcattatt ttagggttcc
    25081 tccagaggat tggtatcatt cgctctataa cttgaaggct cttggtttta atacggtaga
    25141 gacttatgtt gcttggaatt tacacgagcc tcgtgaaggt gagtttcatt ttgaaggtga
    25201 tctggattta gagaaatttc tccaaatagc gcaggatttg ggtctctacg caattgtgcg
    25261 tccgtctcca tttatctgtg cggaatggga attcggtggc ttaccagctt ggctcttgac
    25321 caagaacatg cgaattcgct catccgaccc agcatatatc gaggcagttg gtcgctacta
    25381 tgatcagtta ttgccaagac tggtgcctcg tttgttggac aatggtggca atattctcat
    25441 gatgcaggtt gaaaatgagt atggttctta cggagaagat aaggcttacc tgagagcgat
    25501 tcgacagcta atggaagagt gtggcgtaac ctgtcccctc tttacatcag atggtccatg
    25561 gcgagctact ctgaaagctg gaaccttaat tgaagaggac ctctttgtaa caggaaactt
    25621 tggttctaag gcaccttaca acttttcgca gatgcaggaa ttctttgatg aacatggtaa
    25681 gaaatggcca ctcatgtgta tggagttctg ggatggttgg ttcaatcgct ggaaagaacc
    25741 gattatcaca cgggatccta aggaattggc agatgcagtt cgagaggttt tggaacaagg
    25801 ctctatcaat ctttacatgt tccacggtgg tacaaacttt ggtttcatga atggttgctc
    25861 agctcgagga actttggacc tgccacaagt tacgtcttat gattacgatg cccttctgga
    25921 tgaagaagga aatccaactg ctaaatatct tgcagtcaag aagatgatgg caacacattt
    25981 ttcagagtat ccgcagttgg aaccactcta caaagagagt atggagttgg atgctattcc
    26041 actagttgaa aaagtttctt tgtttgaaac cttagatagc ttgtcaagtc ctgtagaaag
    26101 tctctatcct caaaagatgg aggagctggg acaaagttat ggctacctac tttatcgaac
    26161 agaaacaaat tgggatgcag aagaagaaag acttcgtatc attgatggtc gagatagggc
    26221 ccagctgtat gtcgatggtc agtgggttaa aactcaatat cagacagaga ttggggaaga
    26281 tattttttat caaggtaaaa agaacgggct atctaggtta gatatcttga tagaaaatat
    26341 ggggcgtgtc aactatgggc ataagttctt agcggatacg caacgtaagg gaattcggac
    26401 aggggtctgt aaggatctgc atttcttact aaactggaaa cactatccac tcccactaga
    26461 caatcctgag aaaattgatt tttcaaaagg atggactcaa ggacaaccag ccttttacgc
    26521 ttatgacttt acagtcgaag agccaaaaga tacttaccta gacttgtctg agtttggtaa
    26581 gggggttgcc tttgtcaatg ggcagaatct aggacgtttt tggaacgttg gcccaactct
    26641 ctcactttat atccctcatt gctatctcaa ggaaggtgcc aaccgcatca ttatctttga
    26701 aacagaaggt caatataaag aagagattca tttaactcgt aaacctacac taaaacatat
    26761 aaagggggaa aacttatgac aattgtagga tgccgtattg atggacgttt gatccacgga
    26821 caagtagcca atctttgggc tggaaaacta aatgtttcac gcattatggt tgtagacgac
    26881 gaagttgtca acaacgatat tgaaaagagt ggtttgaaac ttgcgacacc accaggtgtg
    26941 aaattgagta ttttgccagt tgagaaagct gcagccaata ttcttgctgg caaatacgat
    27001 agccaacgtc tctttatcgt ggctcgtaaa ccggaccgct tccttggttt ggtagaagca
    27061 ggtgtaccac ttgaaactct taatgttggg aatatgtctc aaacaccaga aactcgttct
    27121 attacacgtt ctatcaacgt agtagacaag gatgtggaag acttccacaa actggcagaa
    27181 aaaggtgtta aacttactgc tcagatggtt ccaaatgatc caatttcaga ctttttgagc
    27241 ttattaaaat aggaaaaaaa tttttaggag gtcattgtta tgatacaatg gtggcaaatt
    27301 ttacttctca ctttgtactc agcttatcaa atctgtgatg agttgacgat cgtttcatct
    27361 gcaggttccc ctgtatttgc tggtttcatt actggtttaa tcatgggaga tgtgactact
    27421 ggtttactta tcggtggtaa cttgcaactg ttcgttcttg gggttggtac cttcggtggt
    27481 gcttctcgta tcgacgcaac ttctggtgcg gttcttgcga cagccttctc tgtttcacaa
    27541 ggaattgatg caccgcttgc cattactaca atcgctgtac cagtagcagc tctcttgact
    27601 tacttcgacg ttcttggtcg tatgactact accttcttcg ctcaccgtgt ggatgctgca
    27661 atcgaacgct ttgactataa aggtattgaa cgcaactact tgcttggtgc gattccgtgg
    27721 gctctatctc gtgcccttcc agtcttcttt gcccttgctt ttggtggtgc ctttgtacaa
    27781 tcagtagtag acttcgttga agcctacaaa tgggttgcag atggcttgac actcgcagga
    27841 cgtatgcttc caggtcttgg atttgcaatc ttgcttcgtt accttccagt taaacgtaat
    27901 cttcactacc ttgctatggg atttggtttg acagctatgt tgactgttct ttactcatat
    27961 gtaacaggtc ttggtggcgc tgttgctggt atcgtaggta ctcttcctgc tgaagttgct
    28021 gaaaaaattg gtttcgtgaa caacttcaaa ggtttgtcta tgattggtat ttctatcgta
    28081 ggtattttcc ttgcagtgct tcacttcaaa aatagccaaa aagtagctgt agcagcacct
    28141 tctacaccat cagaaagtgg ggaaatcgaa gatgacgaat tctaattaca aacttacaaa
    28201 agaagatttt aatcaaatca acaaacgtag cttgtttact ttccaattag gttggaacta
    28261 cgaacgtatg caagcttctg gttaccttta catgatcttg cctcagttgc gtaaaatgta
    28321 tggtgatgga actcctgaat tgaaagaaat gatgaaagtt catactcaat tcttcaatac
    28381 ttcgccattc ttccatacta ttatcgctgg ttttgacctt gccatggaag aaaaagatgg
    28441 tgtaggttca aaagacgccg ttaacggtat caagacaggt ttgatgggac cattcgctcc
    28501 tcttggggat acaatctttg gttcacttgt acctgctatc atggggtcag tcgcagcaac
    28561 tatggctatc gctggccaac cttgggggat cttcctttgg attgcagttg cagtagcgta
    28621 tgacatcttc cgttggaaac agttggaatt tgcttacaaa gaaggggtta accttatcaa
    28681 caacatgcaa agtaccttga cagctttgat tgacgctgca tctgtacttg gtgtcttcat
    28741 gatgggtgct cttgtagcaa cagtgattaa ctttgaaatt tcttacaagt tgccaatcgg
    28801 tgaaaagatg attgatttcc aagacatctt gaaccaaatc ttcccacgtt tgcttccagc
    28861 aatctttact gcctttatct tctggttgct tggtaagaaa ggtatgaact ctactaaagc
    28921 tatcggtatt attatcgtac ttgctttggc tctttctgcc cttggtcact ttgcacttgg
    28981 aatgtaattc cttatgacta aatcattaat tttggtgagc catggtcgct tctgtgagga
    29041 gcttagaggt agcacagaaa tgattatggg cccacaagac aacatttaca cagtagctct
    29101 tcttccagaa gatggcccag aagaatttac tgctaaattt gaagctgtta ttgaagggtt
    29161 ggatgatttc ctagtctttg cggatcttct cggtgggaca ccttgtaatg tggtcagtcg
    29221 cttgatcatg gaaggtcgtg atattgacct ttacgcaggg atgaatcttc caatggtgat
    29281 tgaatttatc aatgcgagcc ttacaggcgc agatgcggac tacaagagcc gtgctgcaga
    29341 aagcattgtg aaagttaatg acctgttagc gggcttcgat gatgacgaag atgaataata
    29401 ctcttcgaaa atctcttcaa actacgtcaa cgtcgccttg ccgtaggtat atgttactga
    29461 cttcgtcagt tctatctgca acctcaaagc agtgctttga gcagcctgcg gctagtttcc
    29521 tattttagtt ggaactcgat tcaattcatg tgacaacgtg aaaatcgtta gagcatttta
    29581 tatagaatat acatgggaat ggagcttact cccattccta tatttaatag aaaaagagga
    29641 actcaatgct acattataca aaagaagact tgctcgaatt gggtgcagaa atcactacgc
    29701 gtgaaatcta ccaacagcct gatgtatgga gagaagcttt tgaattttat caagcaaaac
    29761 gtgaagaaat tgcagccttt ctacaagaaa tcgctgataa atatgactat attaaagtta
    29821 tcttgacagg tgctgggact tctgcttatg tgggagatac cttgctacct tattttaagg
    29881 aagtctatga cgaacgcaaa tggaatttca atgctattgc gacaacagat atcgttgcca
    29941 atccagcaac ctatttgaaa aaagatgtgg caactgtcct tgtgtctttt gctcgtagtg
    30001 ggaactcgcc tgaaagtgtg gcgactgttg atttggccaa atccttggtg gatgagcttt
    30061 atcaagtgac gattacttgt gcagcagatg gtaaattggc tcttcaagct cacggtgatg
    30121 accgtaatct cttgctcttg caaccagctg tctctaatga tgctggattt gccatgactt
    30181 ctagctttac gtctatgatg ttgacagctc tcttggtctt tgatcctaca gaatttgctg
    30241 ttaagtctga acgttttgaa gttgtatcta gtcttgcccg taaagtttta gacaaggcag
    30301 aagatgtcaa agagctcgtt gatttagact ttaaccgtgt catctatcta ggcgctggtc
    30361 ctttctttgg acttgctcat gaagctcagc tcaagatttt ggaattaact gctggtcaag
    30421 ttgcgaccat gtatgaaagc ccagttggct tccgtcacgg tccaaaatct cttatcaacg
    30481 acaatacagt tgttttggtc tttggtacaa cgacagacta cactcgtaag tacgacttgg
    30541 acttggttcg tgaagttgct ggtgaccaga ttgctcgtcg tgttgtgctt ttgagtgatc
    30601 aagcttttgg tcttgaaaat gtcaaagaag tggcccttgg ttgtggcggt gtcttgaatg
    30661 atatttaccg tgtcttccct tacatcgttt atgcccaact ctttgctcta ttgacttcac
    30721 tcaaggtaga aaataaacca gatacaccgt ctcctacagg tacagtaaac cgtgtagtac
    30781 aaggtgtcat aattcacgaa tatcaaaagt aagacagtgt ttatgaattc ttgacaagag
    30841 gatttgtaaa ttatcagata aaccatagat tgtcagtacg ctttctatgg tttgtttgct
    30901 tgagagaaat agtaaaagga gaacagaatg aaagcataca cagagcgtgt atttggaaat
    30961 gttgagggcg aggatgtctt ggcctatcga tttgagacag acggtggcta ccaacttgag
    31021 gttatgactt atggcgcgac catcttgcgc tatgtcgcac ctgacaaggc tggaaatttt
    31081 gccaatgtta tcttgggatt tgatgacttt gatagttatg taggcaatag tcccaagcat
    31141 ggagcaagtg taggtcctgt agcgggtcgt attgcaggtg cgacctttga gctcaatggt
    31201 aagacctatg accttgaggt taataatgct agcaactgta atcacagtgg ttcaactggt
    31261 tgggattcca gcttgtttga agttgaagaa gtaagcgatc atggcttgac tctctacaca
    31321 gagcgtacag atgggacagg agggttccct ggaaatctca agatttggat cagttatcac
    31381 ttggaagaaa ctggtgccta tgaaatcagc tacaaggtaa cgaccgatca ggatacgctg
    31441 gtcaatccaa ccaaccacag ctatttcaac ttgtctggtg atttcacgca gacgattgac
    31501 cgtcatgtct tccaactaaa cacagagggc atttactcaa tcgctcctga cggtgttcct
    31561 gccaaaactc cagaagccaa ccgtgatgtg gtcaaacaca tctacaatgg taccttgttg
    31621 aaggatatct ttgcagaaga agatgagcaa atccagctgg catcaggttt ggatcaccca
    31681 tttgcccttc ctgtaggcca tgacaatgct ggattccttt atgaccaaaa ttcaggtcgc
    31741 ttcctgcttt tcaagacaga agctccttgc tttgtggtct acacagcaaa ctttgtggat
    31801 gaaagtgtca tcataggagg tcagccaatg ctacagcaca atgggattgc tcttgaagcg
    31861 caagctttac cagatgccat tcacagtgac cttaaaggcc aagtcattct taaagctggt
    31921 caaaccttca ccagtaagac acgttatgaa cttgttgtga aataaaaaag ctggtcaaaa
    31981 agtctttaaa attaaaataa cgcatattgt caggtgatga aaagtttgat aatatgcgtt
    32041 ttattatgaa atgatttact ttatattatc ctgaaatggt gttatttttg agttatctgg
    32101 cttgactttc ttgatggaaa ttatataata gttgtaataa ttataattac aacgagaaaa
    32161 gaggaccatt tatgacctat gaatataaga gtcacattta tttggcagag acagttttaa
    32221 atgtaaagga tttggccagt caaacagcct tttatcagca agttattggt ttagaaatct
    32281 tatctcaaac tgagacagag tccattctag gccttggtga aaaagtcttg gtacagctga
    32341 ttcaagcaca agagagcgga gaagtgaggg aacattatgg tctttaccat ttggccattc
    32401 tcttgcccac acgcaaggct ttggctgatg tcttgaaaca cctgacagat ttacagattc
    32461 ctcttgtcgg cggtgcagac catggttaca gtgaagctat ttacttggaa gatttggagg
    32521 gaaatggcat tgaactctat cgagataagc cagtttccac atgggatatt cgagaagatg
    32581 gacgcattat cggagtgacg gaggctcttg cggcgcagga catttatgag ttgggggaaa
    32641 gagtagagcc ctttatcctg gcagaaggta cgagaatggg gcatattcat ctttccgtca
    32701 aggatagtcg aaagtccagc cagttttatc aaaaggtgtt agggctagag gataaattca
    32761 gtgtgcctag cgctagttgg attgcggctg gagattacca tcatcattta gcagttaacg
    32821 aatggggagg aaaaggtctg gcttcgcgta agcaaggctt accaggttta gcctactatg
    32881 tcatcgaagt cgcacataaa aaagaactgt taacgattgc ccaacgagca caagaagttg
    32941 acgcaccaat caaatggatg acatcgagca aattggaaat cacagactca gatggcatcg
    33001 tgacccgtat tcgtttagca aggtaaaatt aggaattttt aataagttat aagtattgct
    33061 agtttgcttt ttgaacggtc tttggtaaca gaactgcgtg agctggatgg gtgagaattt
    33121 tgacaaagaa gctgattaga gatataatga agaaaaatcg agcaaggaaa aagaaatgac
    33181 aaattcaaag tatattactc gtttgaaacg ttcagagggc cagttgcgtg ggattcaaaa
    33241 gatgattgaa ggagatcgtg acgcaactga cagcagtgag atctagtgta gagcgcgtga
    33301 ttgagatgat aattaccgaa aatcttactg aatgtatcaa tcagccacta gatgattctg
    33361 aagctcaaaa ggaacgctta gaaaaggcta tccgatactt gattaaacgg aaataaatga
    33421 atgttttgag acgatatgtg caaaggtcta ttaactattg gaatagttta atgggagtca
    33481 aaagaagttg taaaaaatct ttaaaattaa aaaaacgcat agtatcaggt attgaaatgt
    33541 actgacccca aaaagttaga ttttttctgt ctaacttttg gggtgcagtt cataagaacc
    33601 ttggtaatat gcgttttatt atggggagat ttatactttt cgaaaatctc ttcaaaccag
    33661 gtcagcttca ccttgccgta gatatggtta ctgacttcgt cagttctatc cacaacctca
    33721 aaacagtgtt ttgagctgac ttcgtcagtt ccatccacaa ccttaaaaca gtgttttgag
    33781 cagcctgcgg ctaacttcct agtttgcact ttaattttca ttgagtatta cttcatcttc
    33841 tcatgaaatt gagtttttgc ccagctcctc ttgattattc tacttgacca ggccaagcat
    33901 tcataccacc ttctacgttg gtaacggtga ggccttggga gatgagaaat tggcaggtag
    33961 atgcagagcg gactcctcct tgacaaataa catagtattc atggtcaggt ttgagttctt
    34021 tgtagccttg ctctaaggta cttaatggaa gatttttggc acctggtgca tgtcctgctt
    34081 ggaattcatg tgcttcacgg acatcgataa gttctagatt ttcattttgg tattttccat
    34141 aaaagtcagc catgctgata ctagtttcca tattctactc cttctgggtt aaccattttg
    34201 tatagtgaat aagcgccgtc aaggttttgg gcggtaaatc ctgcttgctt gaggataggc
    34261 tctgcgatat agctgcgcaa accactgtgg cagctgacga tgtaggcttg ttttttgtcc
    34321 agttcatcag cttcctcctt gacactcggt cagattttga tacaatagta caaaattaga
    34381 ggaggcaggc tatgattcag aaacatgcga ttcctatttt agagtttgat gacaatcctc
    34441 aggcggttat catgcccaat cacgaggggc tggacttgca gttgccaaag aagtgtgttt
    34501 atgcattttt aggtgaggag attgaccgct atgcgaggga agtaggggcg aactgtgttg
    34561 gcgaatttgt ttctgccacc aagacctatc cagtctatgt catcaactac aagggtgagg
    34621 aggtctgtct ggctcaggct cctgttggct ccgctccagc agcccagttt atggattggt
    34681 tggttggcta tggtgtggag cagattatct ctactgggac ctgtggtgtc ctagctgata
    34741 tagaggaaaa tgcctttcta gtccctgttc gcgctctgcg agatgaagga gccagttacc
    34801 actatgtggc accttctcgt tatatggaaa tgcagccaga ggctattgct gctattgagg
    34861 aagttttgga agacagaggg attccttatg aagaagtcat gacctggacg acagacggtt
    34921 tttaccgaga aacggctgaa aaggtggctt atcgtaagga agaaggctgt gctgttgtgg
    34981 agatggagtg ttccgctctt gcggcagtag ctcaattgcg tggggttctc tggggtgaat
    35041 tgttgttcac agcagattct ctagcggact tggaccagta cgacagtcgt gactggggct
    35101 cggaagcttt taataaggcg ctagaactga gtttagcaag tgttcaccac ctttagttgt
    35161 actggcaaag gatttgtttt atcataaaat gtctagctca tacttttcaa aaatatgttt
    35221 aaacgaggtc accttcctct tgtcctaggc atgttgaggt tgggaaaaat ctttaaaatc
    35281 agaaaaacgt atcatatcag gtgatgaaaa ctttgatact atgcgtttta tgttggtaag
    35341 atttagagtg agatgaaatg atactcttcg aaaatctctt caaaccaggt cagcttcacc
    35401 ttgccgtata gatgttactg acttcgtcag ttctatctgc aacctcaaaa cagtgttttg
    35461 agcaacctgt gactagcttt ctaagcgatg ccttggttct cattgcctat aatcaaaaag
    35521 agaaattttc tcctgaaaag catatagagt agctggcgtt aaaagctcct gtctcgcttt
    35581 tttgacctat agtcacatct atcaagtatt gttcttgcct aagctatcaa taaaaaggtg
    35641 gcatttttta ggcttggtgt tagtagattt tgccttatcc tatctaagtc atttcgaact
    35701 ttttatggta caatggaaac atgttattca aattatctaa ggaaaaaata gagctaggct
    35761 tatctcgttt atcgccagcc cgtcgtattt ttttgagttt tgccttggtc attttactag
    35821 gctctcttct tttgagcttg ccctttgtcc aagttgaaag ctcacgagcg acttattttg
    35881 atcatctttt cactgctgtc tctgcagtct gtgtgacagg tctctcaacc cttccagtag
    35941 ctcacaccta taatatatgg ggccaaataa tctgtttgct cttgattcag atcggtggtc
    36001 tagggctcat gacctttatt ggggttttct atatccagag caagcaaaag cttagtcttc
    36061 gtagccgtgc aactattcag gatagtttta gttatggaga aactcgatct ttgagaaagt
    36121 ttgtctattc tatttttctc acgacctttt tggttgagag cttgggagct attttgctta
    36181 gttttcgcct tattcctcaa ctcggctggg gacgtggtct ttttagttcc atttttctag
    36241 cgatctcagc cttctgtaat gccggttttg ataatttagg gagcaccagt ttatttgctt
    36301 ttcagaccga tttactggtc aatctggtga ttgcaggctt gattattaca ggcggccttg
    36361 gttttatggt ctggtttgat ttggctggtc atgtaggaag aaagaaaaaa ggacgtctgc
    36421 actttcatac gaagcttgta ctattgttga ctataggttt gttgttattt ggaacggcaa
    36481 ctactctctt tcttgagtgg aacaatgctg gaacgattgg caatctccct gttgccgata
    36541 aggttttagt tagctttttt caaacagtga cgatgcgaac agctggcttt tctacgatag
    36601 attatactca ggctcatcct gtgactcttt taatttatat cttacagatg tttctaggtg
    36661 gggcacctgg aggaacagct gggggactca agattacgac attttttgtc ctcttggtct
    36721 ttgcacgaag tgagcttcta ggcttgcctc atgccaatgt tgcgagacga acgattgcgc
    36781 cgcgaacggt tcaaaaatcc tttagtgtct ttattatctt tttgatgagc ttcttgatag
    36841 gattgattct gctagggata acagccaaag gcaatcctcc ctttatccac ctcatatttg
    36901 aaaccatttc agctcttagt acagttggtg taacggcaaa tctgactcct gaccttggga
    36961 aattggctct cagtgttatc atgccactta tgtttatggg acgaattggt cccttgacct
    37021 tgtttgttag cttggcagat taccatccag aaaagaaaga tatgattcac tatatgaaag
    37081 cagatattag tattggttaa gaaaggaaag agcatgtcag atcgtacgat tggaattttg
    37141 ggcttgggaa tttttgggag cagtgtccta gctgccctag ccaagcagga tatgaatatt
    37201 atcgctattg atgaccacgc agagcgcatc aatcagtttg agccagtttt ggcgcgtgga
    37261 gtgattggtg acatcacaga tgaagaatta ttgagatcag cagggattga tacctgcgat
    37321 accgttgtag tcgcgacagg tgaaaatctg gagtcgagtg tgcttgcggt tatgcactgt
    37381 aagagtttgg gggtaccgac tgttattgct aaggtcaaaa gtcagaccgc taagaaagtg
    37441 ctagaaaaga ttggagctga ctcggttatc tcgccagagt atgaaatggg gcagtctcta
    37501 gcacagacca ttcttttcca taatagtgtt gatgtctttc agttggataa aaatgtgtct
    37561 atcgtggaga tgaaaattcc tcagtcttgg gcaggtcaaa gtctgagtaa attagacctc
    37621 cgtggcaaat acaatctgaa tattttgggt ttccgagagc aggaaaattc cccattggat
    37681 gttgaatttg gaccagatga cctcttgaaa gcagatacct atattttggc agtcatcaac
    37741 aaccagtatt tggataccct agtagcattg aattcgtaaa gagggatgac ccctcttttt
    37801 tgatgcccaa gatggcaaat agagacagaa gccccttgtc ttctagtaaa agttcttcaa
    37861 aggctggact ttatggtaaa atagaaggaa gtgacaagag agagtaatac tcaatgaaaa
    37921 tcaaagatca aactaggaaa ctagctacgg gctgctcaaa acactgtttt gaggttgcag
    37981 atagaactga cgaagtcagc tcaaaacact gttttgaggt tgcagataga actgacgaag
    38041 tcagtaacat ctatacggca aggcgacgtt gacgcggttt gaagagattt tcgaagagta
    38101 taagaaaaaa tcagtcccct aaaggagcag attatgaagt tattgtctat cgccatttct
    38161 agctataatg cagcagccta tcttcattac tgtgtggagt cgctagtgat tggtggtgag
    38221 caagttggga ttttgattat caatgacggg tctcaggatc agactcagga aatcgctgag
    38281 tgtttagcta gcaagtatcc taatatcgtt agagccatct atcaggaaaa taaaggccat
    38341 ggcggtgtgg tcaatcgcgg cttggcagag gcttctgggc gctattttaa agtagttgac
    38401 agtgatgact ggtggatcct cgtgcctact tgaaaattct tgaaaccttg caggaacttg
    38461 agagcaaggg tcaagagatg gatgtctttg tgaccaattt tgtctatgaa aaggaaggtc
    38521 agtctcgtaa gaagagtatg agttacgagt cagtcttgcc tgttcggcag atttttggct
    38581 gggaccaggt cggaaatttc tccaaaggcc agtatatcat gatgcactcg ctgatttatc
    38641 ggacagattt gttgcgtgct agccagttct aactgcctga acataatttt tatgtcgata
    38701 atctctttgt ctttacgccc cttcagcagg tcaagaccat gtactatctg cctgtcgatt
    38761 tctatcgtta tttgattggg cgtgagggcc agtctgtcaa tgagcaagtg atgattaagt
    38821 gcattgacca gcaactcaag gtcaatcgac tcttggtaga ccagcttgat ttgtcccaag
    38881 tgagtcatcc caaaatgcga gaatatctgc tgaatcatat tgaaatcacg acggtgattt
    38941 ccagtaccct gctcaaccga tctgaaacag cggagcatct ggcaaaaaaa cgccaattgt
    39001 ggacctatat tcagcagaaa aatccagaag tctttcaggc tattcgtaag accatgttga
    39061 gccgtttgac caaacattct gtcttgccag atcgcaaact gtccaatgtc gtctatcaaa
    39121 tcaccaaatc tgtttatgga tttaattaat ataagtgttt tataagaggg atttaagaaa
    39181 aattttaact ttttcttagt cctttttaat ttcaggagat tatactagag tcatcaaata
    39241 aagaaagact ctaaggagaa tcctatgaaa ttcaatccaa atcaaagata tactcgttgg
    39301 tctattcgcc gtctcagtgt cggtgttgcc tcagttgttg tggctagtgg cttctttgtc
    39361 ctagttggtc agccaagttc tgtacgtgcc gatgtggtca atccgatccc aggtcaagtc
    39421 ttacctgaag agacatcggg aacgaaagag ggtgacttat cagaaaaacc aggagacacc
    39481 gttctcactc aagcgaaacc tgagggcgtt actggaaata cgaattcact tccgacacct
    39541 acagaaagaa ctgaagtgag cgaggaaaca aactcttcta gtctggatac actttttgaa
    39601 aaagatgaag aagctcaaaa aaatccagag ctaacagatg tcttaaaaga aactgtagat
    39661 acagctgatg tggatgggac acaagcaagt ccagcagaaa ctactcctga acaagtaaaa
    39721 ggtggagtga aagaaaatac
//
LOCUS       DAVDHC010000019        36196 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVDHC010000019 DAVDHC010000000
VERSION     DAVDHC010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36196
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.019"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(36..884)
                     /locus_tag="VUR43_001332"
     CDS             complement(36..884)
                     /locus_tag="VUR43_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET5413013.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLVPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSKLTEITIEAEI
                     LVGKAF"
     gene            1036..1314
                     /locus_tag="VUR43_001333"
     CDS             1036..1314
                     /locus_tag="VUR43_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413014.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            1316..3379
                     /locus_tag="VUR43_001334"
     CDS             1316..3379
                     /locus_tag="VUR43_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET5413015.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(3457..4713)
                     /locus_tag="VUR43_001335"
     CDS             complement(3457..4713)
                     /locus_tag="VUR43_001335"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET5413016.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            4855..7320
                     /locus_tag="VUR43_001336"
     CDS             4855..7320
                     /locus_tag="VUR43_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET5413017.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     VIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVIAKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            7385..8296
                     /locus_tag="VUR43_001337"
     CDS             7385..8296
                     /locus_tag="VUR43_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET5413018.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            8526..9224
                     /gene="dapD"
                     /locus_tag="VUR43_001338"
     CDS             8526..9224
                     /gene="dapD"
                     /locus_tag="VUR43_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET5413019.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            9292..10422
                     /locus_tag="VUR43_001339"
     CDS             9292..10422
                     /locus_tag="VUR43_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET5413020.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            10434..10973
                     /locus_tag="VUR43_001340"
     CDS             10434..10973
                     /locus_tag="VUR43_001340"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET5413021.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGHTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            10957..11634
                     /locus_tag="VUR43_001341"
     CDS             10957..11634
                     /locus_tag="VUR43_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET5413022.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(11701..12600)
                     /gene="galU"
                     /locus_tag="VUR43_001342"
     CDS             complement(11701..12600)
                     /gene="galU"
                     /locus_tag="VUR43_001342"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET5413023.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYKRTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(12622..13638)
                     /locus_tag="VUR43_001343"
     CDS             complement(12622..13638)
                     /locus_tag="VUR43_001343"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET5413024.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            13850..14289
                     /locus_tag="VUR43_001344"
                     /pseudo
     CDS             13850..14289
                     /locus_tag="VUR43_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206583.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(14404..14829)
                     /locus_tag="VUR43_001345"
     CDS             complement(14404..14829)
                     /locus_tag="VUR43_001345"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5413025.1"
                     /translation="MTNLSSVDSEELFQFYREQRNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(14905..15555)
                     /gene="phoU"
                     /locus_tag="VUR43_001346"
     CDS             complement(14905..15555)
                     /gene="phoU"
                     /locus_tag="VUR43_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET5413026.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(15570..16322)
                     /gene="pstB"
                     /locus_tag="VUR43_001347"
     CDS             complement(15570..16322)
                     /gene="pstB"
                     /locus_tag="VUR43_001347"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET5413027.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(16324..17139)
                     /gene="pstA"
                     /locus_tag="VUR43_001348"
     CDS             complement(16324..17139)
                     /gene="pstA"
                     /locus_tag="VUR43_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET5413028.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(17132..17995)
                     /gene="pstC"
                     /locus_tag="VUR43_001349"
     CDS             complement(17132..17995)
                     /gene="pstC"
                     /locus_tag="VUR43_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET5413029.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(18113..18988)
                     /locus_tag="VUR43_001350"
     CDS             complement(18113..18988)
                     /locus_tag="VUR43_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET5413030.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(19155..20486)
                     /locus_tag="VUR43_001351"
     CDS             complement(19155..20486)
                     /locus_tag="VUR43_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET5413031.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(20487..21194)
                     /locus_tag="VUR43_001352"
     CDS             complement(20487..21194)
                     /locus_tag="VUR43_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5413032.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(21278..21763)
                     /locus_tag="VUR43_001353"
     CDS             complement(21278..21763)
                     /locus_tag="VUR43_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET5413033.1"
                     /translation="MAPTDKEDLIRTLELAPHIEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            21749..22306
                     /locus_tag="VUR43_001354"
                     /pseudo
     CDS             21749..22306
                     /locus_tag="VUR43_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(22497..24188)
                     /locus_tag="VUR43_001355"
     CDS             complement(22497..24188)
                     /locus_tag="VUR43_001355"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET5413034.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSTISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            24324..24770
                     /gene="argR"
                     /locus_tag="VUR43_001356"
     CDS             24324..24770
                     /gene="argR"
                     /locus_tag="VUR43_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET5413035.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNGTEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            24821..27355
                     /gene="mutS"
                     /locus_tag="VUR43_001357"
     CDS             24821..27355
                     /gene="mutS"
                     /locus_tag="VUR43_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET5413036.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQTLAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            27502..29196
                     /gene="patA"
                     /locus_tag="VUR43_001358"
     CDS             27502..29196
                     /gene="patA"
                     /locus_tag="VUR43_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET5413037.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVIGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTDV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(29525..29794)
                     /locus_tag="VUR43_001359"
                     /pseudo
     CDS             complement(29525..29794)
                     /locus_tag="VUR43_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            29986..31752
                     /gene="patB"
                     /locus_tag="VUR43_001360"
     CDS             29986..31752
                     /gene="patB"
                     /locus_tag="VUR43_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET5413038.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELIWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVSDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFK"
     gene            31891..32580
                     /locus_tag="VUR43_001361"
     CDS             31891..32580
                     /locus_tag="VUR43_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET5413039.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            32584..32763
                     /locus_tag="VUR43_001362"
     CDS             32584..32763
                     /locus_tag="VUR43_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413040.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            32750..34099
                     /locus_tag="VUR43_001363"
     CDS             32750..34099
                     /locus_tag="VUR43_001363"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET5413041.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            34223..35683
                     /locus_tag="VUR43_001364"
     CDS             34223..35683
                     /locus_tag="VUR43_001364"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET5413042.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELVAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            35697..36131
                     /locus_tag="VUR43_001365"
     CDS             35697..36131
                     /locus_tag="VUR43_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET5413043.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        10569 a         6957 c         7961 g        10709 t
ORIGIN      
        1 tacggcaagg cgacgttgac gtggtttgaa gagtattaga atgctttccc aaccaaaatc
       61 tctgcttcga tggtaatctc tgtcagtttg ctccagtcaa ttttgctctg gtcaacgtga
      121 aagaggagag gagtcatact gagtagggct tggagttgtt ctgctgtgat agtcttagtc
      181 agagaggcag tttgactaga taggatggta aagtgttcct ggaaatgctc cttgatatct
      241 tggttagaat actccttgtt tgtcagctgg tcctgtactc tttgacggat ttctttgagg
      301 tgattttcag ttgggataac ctttatcaag ataccgtctt tggataaaac gcgacgaaat
      361 tctccatagt tggcaggtga gaagatatca agcagaatat ccatgttagc gtcttttata
      421 ggaagtcgtg ccaagtcgcc aacgaaccaa ttgactgccc agttgggttc acttttagca
      481 gcgatttgga ctgaatcttt ggagatgtca aaggcataga aagttttttc agagtgactt
      541 tcttgtagtt tgcgagaata gaatccttca ccacaaccga tatccaaaat tgttgtggta
      601 gtttttgagc ttgcaagcaa gtcagataca gcatctaaga tagcttggta aaagccggct
      661 tctaggattt gttgacggtt ttgaaaattt tccttgtcgt agttagcaga ttgcttgatt
      721 tgagggacta gattgacata gccaaatttc gccaagtcaa aagaatgacg gttgcagcac
      781 ttgaaattag tctctaacag agtcagattt tcttgacaga taggacaggc aaaggcagtc
      841 gcagaagcaa aacgctgaag tttgggcttg agatttgtat tcatagttta agtgtatcaa
      901 aagaggcaaa tgaaagcaac tttaggaata agtagatggg agattcagta gaaataaaac
      961 taattctcca atttatagaa tgaaattgct tttatatcta aattgctata taataatgat
     1021 aaggaggaaa taagtatgtt aaaagaagta ttaaccgttg caaaagttgc gaaaaaatct
     1081 tcattatttt tgggtggtgt cgcatttggt acccttggtt tgaaaatctt agcaagtaag
     1141 gaagctaaaa aaggttattc taaagctttg gctaaggctt acaagttgaa agacgagcta
     1201 gatgcatctg tttctgttgt gaagcaacat ggagacgatg tcttgcaaga tgccaaatat
     1261 ttgtacgagc aagagaaaaa agaagagcaa ttagatagcc ttataggtga ataatatgtc
     1321 ttttaaagtg ctacatagag gataccaaca tatccgacta tcatcttctt tttcacttac
     1381 cttggatatt caagactatc ttcgttcctt ggcgagagat gaaaagggga ttgagtctat
     1441 ccagttttac atggatcaac agcactttac tctacgcata aaagaaggct tttctgtatt
     1501 agataatgca gaagcctttt taaaaagaat tgataaaggg aaagtttctg agttgatgac
     1561 tcttcccatt cgtagagaag agagtgctta ttctattgtt tcaggtgcag cggttaagcg
     1621 tgtacttttt cgtagttttg tgccgtatcc tattcgctat atatggactt gttatcaggc
     1681 tttgggttat attagagaag cctatcaaac actagcgcgt aaggaactaa cgatggaagt
     1741 cttggactgt tcggctattt tattgtcttt gtttatgaac caatccaaga cagctagcaa
     1801 tatcatgttt atgcttgatt tggggaatca tttagatcag tggtccttga aaaaaactgc
     1861 aacagattta gaacagagtc ttcttgcaaa agagagcgat gtattcctag tacagggcga
     1921 tacggttgtt agtatcaaga gttccgatgt tcaaatagga gatgtcttga tcttatctca
     1981 aggaaatgaa attctgtttg atggacaagt agtttcaggt ttaggtatgg tcaacgaaag
     2041 ttccttgaca ggagagagtt ttccagttga aaaaagagag tctgatttgg tttgtgcaaa
     2101 tacagtatta gaaactggag agttacgcat tcgtgtaaca gataatcaga tgaacagccg
     2161 tattttacag ctgattgagt tgatgaagaa atctgaagaa aacaagaaaa cgaaacaacg
     2221 ctatttcatc aagatggcgg ataaagtcgt caaatataat ttcttggggg ctgggctgac
     2281 ttacctattg acaggttctt tttctaaggc tatttctttc ctattggtcg atttctcctg
     2341 cgctttgaaa atctctactc ctgtagctta tttgacagtt atcaaggaag ggttgaaccg
     2401 tgaaatggtg attaaggatg gagatgttct ggagaaatat ctggaagttg atactttctt
     2461 gtttgataag acaggaacaa tcacaactag ttatcctata gttgaaaagg tgttaccttt
     2521 tggagactat agtgaggaag atattctcag aatcagtgcc tgtcttgagg aacacattta
     2581 tcatcctatt gctaatgcca tcgtcaagca agctgagata gagggaattg aacatgagga
     2641 aatgcatggg aaactccaat atatcgcaag caaggggatc aaatctcata tagatggcca
     2701 accagttctt attgggaatt atgtcttgat gcaggatgag cagattcata tcagttcaga
     2761 acaaaatgct ttaattgaag agtacaagag tcactacaat ctcttattct tggcttatca
     2821 aaatgaattg attggaatgt tctgcattca tactcctttg agaaaagaag caaaaacagc
     2881 cttggataaa cttaaggcac aggggaaaaa attgattctg gcaacaggag acaccttgat
     2941 taggacagag gaattagtca aagatttgcc ctttgatcag gtctatacag acttgaaacc
     3001 tgatgggaaa tttgagttag tagagaaact gcagaaagca ggtcacacta ttttgatggt
     3061 tggagatgga ttgaatgact cagcggcttt aactctatca gatatcggtg tggtgatgaa
     3121 tgagagtgca gatatttcta agcagatgag tgatatctta ttgttagata atcgtttgga
     3181 tttcttccaa gagttggatt cgttatcatc atctttgcaa acactcatca agaaaaatat
     3241 tcaggatacc gttgtcgtaa atagtagttt gattggcttt ggcttattta attggttcag
     3301 tccttcaaat ctctctatct tacataatct aacaaccttg cgcattgtcc tgcgtagcct
     3361 gtctattaaa aatagataga tgagagttat taacagcaaa aaggagttac ctttctcgag
     3421 gttaactcct ttgtttatag ataaatgttg aatagtttag taagtcaata caaagtattt
     3481 tttcttccca cgacggataa cagtcagttc attctctaac ttatcagcgt cactcaagac
     3541 atagtcaagc tcttggatgc ggtcgccgtt tacgtagatg gctccgtttt ggacgtcttc
     3601 acgggcttgg cgttttgagt taactatacc agatgagacg agcagttcca cgatattgtt
     3661 gttttcgtct gcctgtactt ggtagttggg cacaccacga agtccttgtt tgagctcttt
     3721 gacagaaagg tttttgatgt ttcctgcaaa gagttgctca gtgatgttaa gtgcttcttt
     3781 gtaggcttct tctccgtgaa caagtgtaac aacttcacga gccaagactt tttgagccaa
     3841 gcgttcgtgt ggcgctgctt caaattgttt acgaatatct tcaatctcat caagtgacaa
     3901 gaaagtaaag attttcaaga agcgaacagc gtcagcgtcc atcacgttca tccagaattg
     3961 gtacatttcg tatggagaag tcttttcggg attgagccag acggcatttc cttctgattt
     4021 accaaatttc ttaccagttg catctgtgat tagtggaaca gtgataacgt gaccagtctt
     4081 gtccgcctta cgacgaagca attcggtacc agctgtcata tttccccact ggtcagaacc
     4141 accgatttga agagtgacat tatggtcttg gttaaggacg aagaagtcat acccttgcat
     4201 gatttggtaa gcgaactcag tgtaagaaat tcctgtttcg atccgttttt taacagattc
     4261 cttactcatc atgtagttga ccgtgaagta ttttccaata tcacggagga agtcaatgaa
     4321 gctgatgctg ccaaaccagt cgtagttgtt gaccatgaca gccttgtttt cgccattttc
     4381 aaagtcaaga aaacgagaaa gttgtccttg gatagacttg acccagccat ctactgtgtc
     4441 ttttgtttgg agactacgtt cagcatcttt gaaggacgga tctccgatga gacctgtagc
     4501 accgccaacg agcgcataag gtttgtgacc tgctagttgc aagcgacgac ttgtcaagat
     4561 tgcgacaagg tggcctaggt gaaggctgtc agcagttgga tcgtagccag tataataaga
     4621 aacttgacct tcttctaggg ctttacgcaa agcttcttca tcagtcgttt gaaatatcaa
     4681 accacgctct tttagctcat caaaaatgtg catgtgtttt ttctcctttt taaaattatt
     4741 gtttctacct attgtatcac aaacttgggc aatagcctag cagaataggg aagaaagtgg
     4801 ctattttatt gaaaatttcc cttttgtggt ataatagata aagtgaggaa atccatgcaa
     4861 aatcaattaa atgaattaaa acgaaaaatg ctggaatttt tccagcaaaa acaaaaaaat
     4921 aaaaaatcag ctagacctgg caagaaaggt tcaagtacca aaaaatctaa aaccttagat
     4981 aagtcagtca ttttcccagc tattttactg agtataaaag ccttatttaa cttactcttt
     5041 gtactcggtt ttctaggagg aatgttggga gctgggattg ctttgggata cggagtggcc
     5101 ttatttgaca aggttcgggt gcctcagaca gaagaattgg tgaatcaggt caaggacatc
     5161 tcttctattt cagagattac ctattcggac gggacggtga ttgcttccat agagagtgat
     5221 ttgttgcgca cttctatctc atctgagcaa atttcggaaa atctgaagaa ggctatcatt
     5281 gcgacagaag atgaacactt taaagaacat aagggtgtag tacccaaggc ggtgattcgt
     5341 gcgaccttgg ggaaatttgt aggtttgggt tcctctagtg ggggttcaac cttgacccag
     5401 caactaatta aacagcaggt ggttggggat gcgccgacct tggctcgtaa ggcggcagag
     5461 attgtggatg ctcttgcctt ggaacgcgcc atgaataaag atgagatttt aacgacctat
     5521 ctcaatgtgg ctccctttgg ccgaaataat aagggacaga atattgcagg ggctcggcaa
     5581 gcagctgagg gaattttcgg tgtagatgcc agtcagttga ctgttcctca agcagcattt
     5641 ttagcaggac ttccacagag tcccattact tactctcctt atgaaaatac tggggagttg
     5701 aagagtgatg aagacctaga aattggctta agacgggcta aggcagttct ttacagtatg
     5761 tatcgtacag gtgcattaag caaagacgag tattctcagt acaaggatta tgaccttaaa
     5821 caggactttt taccatcggg cacggttaca ggaatttcac gagactattt atactttaca
     5881 actttggcag aagctcaaga acgtatgtat gattatctag ctcagagaga caatgtctcc
     5941 gctaaggagt tgaaaaatga ggcaactcag aagttttatc gagatttggc agccaaggaa
     6001 attgaaaatg gtggttataa gattactact accatagatc agaaaattca ttctgccatg
     6061 caaagtgcgg ttgctgatta tggctatctt ttagacgatg gaacaggtcg tgtagaagta
     6121 gggaatgtct tgatggacaa ccaaacaggt gctattctag gctttgtagg tggtcgtaat
     6181 tatcaagaaa atcaaaataa tcatgctttt gataccaaac gttcgccagc ttctactacc
     6241 aagcccttgc tggcctacgg tattgctatt gaccagggct tgatgggaag tgaaacgatt
     6301 ctatctaact atccaacaaa ctttgctaat ggcaatccga ttatgtatgc taatagcaag
     6361 ggaacaggaa tgatgacctt gggagaagct ctgaactatt catggaatat ccctgcttac
     6421 tggacctatc gtatgctccg tgaaaatggt gttgatgtca agggttatat ggaaaagatg
     6481 ggttacgaga ttcctgagta cggtattgag agcttgccaa tgggtggtgg tattgaagtc
     6541 acagttgccc agcataccaa tggctatcag accttagcta ataatggagt ttatcatcag
     6601 aagcatgtga ttgcaaagat tgaagcagca gatggtagag tggtgtatga gtatcaggat
     6661 aaaccggttc aagtctattc aaaagctact gcgacgatta tgcagggatt gctacgagaa
     6721 gttctatcct ctcgtgtgac aacaaccttc aagtctaacc tgacttcttt aaatcctact
     6781 ctggctaatg cagattggat tgggaagact ggtacaacca accaagacga aaatatgtgg
     6841 ctcatgcttt cgacacctag attaacccta ggtggctgga ttgggcatga tgataatcat
     6901 tcattgtcac gtagagcagg ttattctaat aactctaatt acatggctca tctggtaaat
     6961 gcgattcagc aagcttcccc aagcatttgg gggaacgagc gctttgcttt agatcctagt
     7021 gtagtgaaat cggaagtctt gaaatcaaca ggtcaaaaac cagggaaggt ttctgttgaa
     7081 ggaaaagaag tagaggtcac aggttcgact gttaccagct attgggctaa taagtcagga
     7141 gcgccagcga caagttatcg ctttgctatt ggcggaagtg atgcggatta tcagaatgct
     7201 tggtctagta ttgtggggag tctaccaact ccatccagct ccagcagttc aagtagtagt
     7261 tctagcgata gcagtaactc aagtactaca cgaccttctt cttcaagggc gagacgataa
     7321 ttctctaaat gaagtggcca atcaatggat tgccactttt ttcttttcgt gttacaataa
     7381 gggtatgaat cagtatcaga aaaagattgt taacggaaaa atttattcgc tcctatccgg
     7441 cttaatatgg ggaatctgtg gaattttagg agagtacttc tttactcatt atcaggtgtc
     7501 ttcgggctgg attacctcta tgcgtttgac actggcaggg agtcttgtac tcatttggtc
     7561 tgcaatacaa ttaaaatcgc aagtgctaga tatttggcga gacaagaaaa attacctgcc
     7621 ctttttagcc tatgctattt tggggatttt ttcagttcag tattttttct atctctgtgt
     7681 agaatactca aatgctacga cagcaactat tttacagttt attagccctg tttttatcct
     7741 cttttacaat cgcttggttt atcaaaaacg agcgtcaaaa agcgctgttt tctatgtttt
     7801 ggttgccatg ctgggtgttt gcttgatggc gacaaaggga gatctctctc agttatccat
     7861 gacgccgcta gctcttataa caggtttgct gagtgctatg ggtgttatgt ttaatgttat
     7921 cttgccccaa ccttttgcta agcgttatgg ttttgttcct acggttgggt gggggatgat
     7981 tttggcaggt ttgtttagca atgtcctctc gccggtttat cagctttcct ttactcttga
     8041 tatttggagt atcttgattt gcctcattat cgctttcttt ggaacggctt ttgctttttt
     8101 catttccatg aaggctgtgt ccttggtttc tcctttggtg gttgccgtta tcagtgccag
     8161 tgaacctctc tcttctgctc tcttgagtgt tttgttctta ggattagtag tggattggtc
     8221 cctccttcta gctatagcct tgattatttt acccatgata tttttgtcta tagaagaagc
     8281 gaaagaaagt agataaaaag tcttttctta attctaaaag tgtgctatac tagaatagtc
     8341 aataaaacac ggggagatag ttgtgaagag tgtttttagg ttgtatcggt aggggcttgc
     8401 ttttaccgac agcacgtttt atctcacatc cctaaaaaat catacctaaa aacagacaaa
     8461 aaggtttcaa atttgaggcc ttttttggta gaataggtat cattataacg aaccaggagg
     8521 cacctatgac tgctacaaaa atgaacgctc aagaaattat ccaatttatc gccaatgctg
     8581 aaaagaaaac cagtgtcaaa gtaacctttg aggggcaact cgcaactgct gtgcctagct
     8641 ctgttgtcaa actaggaaat gtcctattcg gagactggaa ggacgtggct ccgcttcttg
     8701 aaggtttggt agaaaatcaa gattatgttg tcgagcaaga tgctcgtaat tctgcagttc
     8761 ctttgctaga taagcgtgct atcaacgctc gtatcgagcc aggtgctatt atccgtgacc
     8821 aggtggaaat tggtgacaat gctgttatca tgatgggagc tgttatcaat atcggtgctg
     8881 aaatcggtgc tggaaccatg attgacatgg gtgccatcct tggtggccgt gctatcgttg
     8941 gaaaaaatag ccacgttggt gcaggtgcag ttttggcagg tgtgattgag ccagctagtg
     9001 ctgaaccagt ccgtgtcgga gacaatgttc ttatcggtgc taatgcagtg gttatcgaag
     9061 gagtccaaat cggtagtggt tcagttgtcg ctgcaggagc tatcgttacc caagatgtcc
     9121 cagaaaacgt ggtagtagca ggtgttccag ctcgtatcat caaagaaatt gatgctcaaa
     9181 cccaacaaaa aacagcgcta gaggatgcgc ttcgtacctt gtaattgtaa aagtaaaaaa
     9241 gaggcggaac cctttttcca gcctctttct gctatatcgg aggacagata gatgttagat
     9301 ttgattcaga ctagacgagc tttacaccag attccagaga ttggcttgga ggagttcaag
     9361 actcaggctt atttgctgga tgtgattgag aaattgacta cgggcaagga ttttgttcaa
     9421 attcgtactt ggcggacagg gattttggtc tacctgcagg gaagtcagcc ggagcgaacc
     9481 attggttggc ggacagatat tgatggtctg cctatcgtcg aacaaacagg tctacctttt
     9541 gcttctcaac accaaggtcg catgcatgcc tgtggccatg attttcatat gaccattgcc
     9601 ttaggctgtc ttgagcgcgc ccttgaggag caacccaaga ataatctgct ctttctattt
     9661 cagcctgctg aagaaaatga agctggtggt atgctcatgt atgaggacgg tgcttttgga
     9721 gattggttgc caaaccaatt ctatggtctc catgttcgtc cagatttgaa agtcggccag
     9781 attgcgacta atactcatac actctttgca ggaacttgcg aggtgaagat ccgtttcaaa
     9841 ggcaaaggtg gccacgcagc ttttcctcat gaagccaatg acgccttggt ggcggctagt
     9901 tactttgtga cccaagtgca gtcagttgtt agccgcaatg tcaacccaat cgagggagca
     9961 gtggtgacct tcggcgtttt tcaagctgga accaccaaca atgtcatcac agacacagct
    10021 tttttacatg gaactattcg tgccttgaca caggacatga gtctcttggt gcaaaagagg
    10081 gtaaaaacag ttgcagaagg ggttgcagct gcctttgata tggaagtcga agtggaactc
    10141 aaacaaggtg gatacctacc tgttgagaac aatccagcct tggcgcgtga actgatggac
    10201 ttctttgacg aaaaagacgg aatcgagttg attgatatcg aacctgctat gacaggcgag
    10261 gactttggtt atctcctttc aaaggttgat ggcgtgatgt tttggctagg tatcgatagt
    10321 ccctacgctc ttcatcaccc tcaaatgagt cctaaggaag aagtcttagc tattggggtg
    10381 gctgcggtgt ctagtttcct gaaaaagaag gcagcagaat agagggcttg tctatgaaat
    10441 cggaattacg caagcaagtc ttgcatgaaa tgaaggcttt atctcaagaa caaaaacagg
    10501 ctatagacca agctttaacc gagcgaattt tacaacaccc cttttatcaa gaagccaagg
    10561 tcatcgcaac ctacctctct ttttctcatg agtttcaaac gcgggaactg attgagcagg
    10621 cgctgaagga cggcaagaag gttttaatac ccaaaactta tcccaagggg cgcatggact
    10681 ttgtagtcta tgatccgcag cagttggtaa aaactgcctt tgccttactg gagccacagg
    10741 gagatttgga agtggtggat gtatctcaga ttgatttgat tcatgttcct ggcctggctt
    10801 ttacgacgga tggatatcgg attggatatg gtggaggtta ttatgaccgc tatctggaac
    10861 atttttctgg tcatactttg agtacggttc atccttgtca aattcaggac tttatacctg
    10921 aaaaccatga tattcctgtt caggaggtat taattgatga aggaaatctt tgatagacgt
    10981 taccctgtga cgagtttctt cctcttagtg acggccttgg tatttttact aatgttggtc
    11041 actgcaggcg gaaactttga cagggcagat acattatttc gatttggagc catgtatggg
    11101 ccagctattc gcctctttcc cgagcaggtt tggcgtctct tgtctgccat ttttgttcat
    11161 attgggtggg aacatttcat tgttaatatg ctttcacttt attatcttgg aaggcaggta
    11221 gaggagattt tcggctctaa gcagttcttt tttctctatc tcttatcagg aatgatgggc
    11281 aatctctttg tttttgtatt tagtcctaaa tccttagcag caggcgcctc tacctctctt
    11341 tatgggctat ttgccgcgat tattgttctt cgctatgcaa ctcgcaatcc ttatatccaa
    11401 cagctagggc aatcctatct gacacttttt gtggttaaca ttattggaag tgttctgatt
    11461 ccaggaatca gcctagcagg ccatatcggt ggtgcagttg gtggcgcatt tctagcagtt
    11521 atctttccag ttagaggaga aaaacggatg tataatacca gccagagatt aggagcggta
    11581 gtcttgttcg taggactcgc cattttgctt ttctacaagg gaatgggaat gtgacgaagt
    11641 tgaaagaaaa tttgtgtaat gaaaaaagat aaggcatttt ttgaacctta tctttttatt
    11701 ttattccttc tcagtcaatt cttttccaag ttggatgagg taattcttca aatcatcttt
    11761 gacttgtggg tgtttgaggg cgtagtcaat agatgttttc ataaagccaa acttatcccc
    11821 aacgtcgtaa cgagctcctg taaattcacg ggcaaaaaca cgctgtgttt tattaagagt
    11881 atcgattgca tcagtaagtt ggatttcatt tccagcacca ggagcttgct tttcgagaat
    11941 ctcaaaaatt tcaggcgtga ggaggtagcg tccgataata gcaaggtcgc taggagcgtc
    12001 ctctggagct ggtttttcaa caaaggtttc aacactgtaa agaccatctt ttccttcgcc
    12061 ttgcggagca ataaccccgt aagcagatac ttcgtcatga gggactggca tgacagcgat
    12121 agtagacgcg tgggtacgct tgtagtcatc catgagttgt ttggtaagtg gaacagcctt
    12181 ttcgtctgtg atatccatca agtcatcacc aagcataacg acaaaaggtt catttccgac
    12241 gaaagccttg gcttgcaaaa cagcatctcc gagaccgcgt ggatgagttt ggcggataaa
    12301 atgcagacgc atgccagttg tttcatcaac tagcttcaaa agatctgttt tccctttttc
    12361 tttgaggtta tattccaatt cgaagtttga atcgaagtgg tcctcaatag aacgttttga
    12421 tttaccagtg acaactagaa tatcttcaat acctgatttg agagcctctt ccacgataaa
    12481 ctggatagtt ggtttgtcta cgattggcaa catttctttg gcaagggcct tggttgctgg
    12541 taaaaatcga gttcctagtc cagcagcagg gataactgcc tttctaactt ttgatgtcat
    12601 aaaaatcctt tctatagagg gttaagacca ctcattttct gctttaaatt cattgttcat
    12661 gatgtcataa atggcatctt tgatattggt tccgtgataa ataacttggt aaatagcctg
    12721 tgtaatgggc atatagactc caagttcttg ggctagttca taggctgctc gagtcgttga
    12781 aattccttcg attaccatgc ccatattagc ttctatatca gctagggatt ctcctcgtcc
    12841 gagagcatct ccagctctcc agttacgaga gtggatggaa gttcccgtta cgatcaaatc
    12901 tcccacacca gataagccgc tataggtcaa tggactggcc ccgagtgcta cccctaggcg
    12961 ggtgatttct gctaaacctc gagcgatgat ggctgcctta gcattatcac caaatccaag
    13021 accatgtaaa gctccagcac cgacagcaat aatattttta agagcaccag cagtttcaac
    13081 cccgataaca tccgtattgg tataaagtcg gaagtagtga ttactaaata gctcctgaac
    13141 gtattgagct gtttgtaaat ctttagaagc agcagttatt aaagttaggt cacgcacaat
    13201 ggtctcttct gcatgactag gccctgaaac aacgacgata tcactacgga gatgttcagg
    13261 aatttcttct tcaagaatgg ttgataatcg tttatggcta tcaggttcta atccctttga
    13321 tgcgtgcatg atgataacct tatggtccaa ggtttgtgca acttgctggg caacaagtcg
    13381 tgtcactttt gttgggacaa caaacaaaat cgcatccaca tttttcaatg tttctgctaa
    13441 gtcggtgtag gcaatgatat tttcgtctag aacgacatct ttaaagtagt gcttattagt
    13501 atggtgtgta ttaatttcat tgatttgctc gggaagattt ccccaaatac gtacctcgtg
    13561 tccattgtca tttaagactt gtgaaagggc ggttccccaa gaaccaggcc ccaagacggc
    13621 gacggtttgt ttttccatga tttcctcctt gatagatttc tttctcttat tctatcatat
    13681 tctaggggat tttgcacttg cattactggg gtatggtgga aaaatacaca aaaaccgaga
    13741 cgaagggata aactcttagt ctttagttaa agtgagaaga aatctgatag atagtttgat
    13801 tcagtatatg cttataatag aggtaaacaa ctcaggaagt tcttgtaggt tgcgagagtt
    13861 tggcaaaaaa attaaaagat tacgtttggc taaaaaaatc agtcgttcag aattttgtgg
    13921 tgatgagtct gaattaagta tccgtcaatt aattagaatt gaaaatggag aatccagacc
    13981 aatactaaca aagttaaaat atattgctga acgtttgggg gttgaagatt acaagttgat
    14041 gccaagttat atagagttgg ataaggaata cctagaattg aagtatttct tgatgaggat
    14101 tcctacatac gaagatgaaa ctatcgccca aaagaaagag agtgttttga taagattttt
    14161 gaagagtatt atgataggtt acctgaggaa gaaagattta tcatcccaaa ttattcatat
    14221 ctggcactaa cgaactacac agttcaaaaa ttaccagaaa agctagttga aatactgtcc
    14281 ttctggtgat tttgcttaat ttctgatgtt cgagacataa ttgaggagat ttgtcttgat
    14341 tttttcctaa aaaagggcag actcctccct tggtttgatg ctcgattttt aaaataaggt
    14401 gacttattct gttaggcatg ttttcccctg ccctctagct ctatatggaa cagggagtat
    14461 cagatttatc tggcagattg tatcaaataa ggcttgaaac tgttttgaat aggcgtatag
    14521 acttgagaat ttgagaatat gtcgtctagc agtagagaca tattttccgg caatatgaag
    14581 gaagagacgt cgaaaacgct tgatagtcaa ggactttact tcatcaccag ctagctgctt
    14641 taaaaagagg tagagattat aagccagaca gcccatcatc atacgtactt cattcttaat
    14701 catggtcgaa ctatctgtct tatccccaaa gaatcctgct ttcctttctt tgataaagtt
    14761 ttcagcattc ctttgttcac gatagaattg aaacagctcc tcactatcta cactgcttaa
    14821 attggtcaaa tgaacttttt tacaaccata aaaaagagca cttaatcgta ctcttctctt
    14881 ttaaggatta aaggattagt tgaattaatt caaatccact agttctcctg tttctaggta
    14941 gactaggcgt tcacaaatgt tagcaatgta atcagcgaag cgttccagat gccctatgat
    15001 ataaaggtat tgagttccat tgggaattga ggtttcttgg tctttcataa gtccaatgat
    15061 ttcctttgat aaggcataat aatattggtc aatctgttca tctttttgag caatactaat
    15121 agcttttgag gcttggtgca aaggaaaggc aaccaataaa tcggctagca tgctgaggga
    15181 taatttaccc atttggtgta actgttcttc gtcaggggct agttgatttt cttttagttg
    15241 caaaacagct ttggcaatgc ctgccatatg gtctcccata cgttcaaggt ctgaacaaga
    15301 agacatgatg ctaatcacaa atcgaaggtc agacacttgt ggctgctgca aggccaacaa
    15361 acgggcacag gtcaattcga tagcgctttg accttggttg atagcatgat ccttattgat
    15421 aattagctct gccatctcct tgtctttgga ggctaaggcc agtaaggctt ttgaagctgt
    15481 ttcaaggaca agttgcccta gtcctaaaaa ggattgttct aattcatgca attctaagtc
    15541 aaattgattt ctcataggtt tttccttcct tatccgaacc gtcctgaaat atagtcttct
    15601 gtgcgctgat cttttggatt ggtaaacacg tcaacggtat ctccaaattc gcaaatttct
    15661 cctgttaaga aaaaagcagt tttatctgaa atacgtgaag cttgttgcat gttatgggta
    15721 acaatgataa tcgtataatc cttttttagt tgctgaatga ggtcttcaat ttttaaagtg
    15781 gagatagggt ctaaggctga agtcggctca tccattaaca gaacatcagg ttctactgct
    15841 aaagctcgcg caatgcaaag gcgttgctgc tgaccgccag ataaggacat ggcactcttt
    15901 ttaagatcat ctttgacttc ttcccaaatg gctgcccctt ttaaagattt ctccactaag
    15961 gcatctaatt gttttttgtc tcgaatacca tgtgtccttg gaccataagc cacgttatca
    16021 tagatagaca tggcaaaggg attaggctgt tgaaaaacca tccctacacg cttgcgtagc
    16081 tgattaaggt tgaatttgct actataaata tcttgctcat ctaagaggac ttggccttca
    16141 atatggcaag aaggaaccaa atcgttcatc cgattaaggg tttttagaaa agttgatttg
    16201 ccacaaccag atgggcctat caaggcagta atctgtcttt ctggtaattg aatcgaaata
    16261 ttttttaagg cttgaaaatc cccgtaaaat aagtctaggt gtctgactga aaatgttccc
    16321 atactaggaa gctcctttca caagtttccg agataataag cttgatagag tatttatcat
    16381 taaaacagta ataatcaaaa tcacgccggt agcataggct tcattgacat gtagcccctc
    16441 acttgacagc atatacatat gtagggctag agaacggcct gaagacatga gactacttgg
    16501 cgtattggta gaggtaccta atgtatacat gagggcagct gtttcaccaa cgatacggcc
    16561 aatagctagt atcactccag ctaaaatacc tggcatggca actggtagaa caattctaaa
    16621 aacagtccgt aacttacctg ccccaagtcc ataacttgct tgacgcatgc tatcactaac
    16681 agataaaagg gcttcttctg ttgagcgaat aatgactggc aacaccatga taactgaggt
    16741 taagattcct gataacagag agtattgaaa acctaagaag actacaaaga agagcatgcc
    16801 aaacagacca aaaacaatgg aaggaatccc agacaaggta tctgaggcca atcgcatgat
    16861 tttaacacaa agggaatctt tttttgtata ttccacaaga taaaaaccag caaaaatccc
    16921 tatgggcaag gctaaaagaa gagcaccaaa gaccagaata acggtggaaa taatcgctgg
    16981 cataagggaa atgttctcag aagtataagt ccaagaaaag agggatagac ttagatgagg
    17041 taagcctttg atgaggataa aaccaatgat taaaaagaga gagccaaagg ttaaagctga
    17101 aaaacaataa acgagaagtt ttagcaggta tttactcata agatgatttt cctttcaagt
    17161 aggcaaagta ggcattaatc aagagaataa ggaaaaagag aactgctgag gttgcaataa
    17221 gggcttccct atgctgacct gatgcgtaag ccatttccag aacaatattg gttgttaagg
    17281 ttctggttcc tgaaaagagt ccacttggaa taatcggctg gttgcctgcc accaaaataa
    17341 ctgccatggt ttcacctact gcgcgaccaa ttcctaaaat aactgctgat aaaataccag
    17401 atctcgcagc tggcaagatg acactaaaaa tactccgttc atgactagct cctagagcca
    17461 agctaccaga ataatacgtt ttgggaactg ttcggatagc agattctgac aaactgataa
    17521 tggttggcaa aatcattatt cctaatagta acgaagcggt taggacactc atgccatttc
    17581 ctaaaaagct tctaatccaa ggcaccaata attgtaggcc gaaaaaacca taaacaatag
    17641 atggaatggc cgccatcaag ttgatagctg attttaagaa gccatagacg ggctttggac
    17701 aataataaac cataaacacc gatgtcaaga tgcctgttgg caccccaatc acaatcgctc
    17761 ctaaggtaat taataaggaa ccaacgatca ttggtaaaat accatagctt gccggaatgt
    17821 tcgttggcga ccaatcactg cctaataaaa aacgggcaaa gccgtagtta gccatgaaag
    17881 gtaagccatt actaaaaata aagaaacaga ttagcaaaat agctacaaca gctactgttg
    17941 cactcatgaa aaaaattgcc ctaaaaactg cttctttgaa ggcttgtttt gtcacatctt
    18001 gtcctttcta gtgaagaaag taagggagat acgacacctc cctacttgcc ttctttatct
    18061 tattgtacga tgaaacgtct gcatctcttt agagatttat ggagcaaaca ttttatttaa
    18121 tcttgtccca ggtggttaat ttgccactaa aaacgtctgc aagttcagcc atactgactt
    18181 ggcttgcctt attgtcatta ttgaccacaa cagcaatacc gtctaaagca atagcatcat
    18241 gggtgagact cttaccttct tcaggagtta attccctaga aaccatacca atatcagcgg
    18301 ttttctcctt aacagcggta atacctgctg aagacccatt agaggtaata tcaatcgtaa
    18361 cttctggatt ttctttttta taagcttctg ctaatttttc cattaaagaa gatactgaag
    18421 tggaacctac aacagacaac ttgcctgata agtgttggct tgtatattct gtggtttcgg
    18481 ttttagcttc aataaattta ttatctgtga ccacttgttg accttgtttg gagtggataa
    18541 agctgataaa atcttgacct agcttggaaa gattagaaga ccaaacaatg ttgaagggac
    18601 gttgaagagg gtattcacca tctaaaactg tgtctcgact agccttgaca ccatcaatct
    18661 ctaaagcctt gacagatttc gttaaagatc ccaaggagat gtagccgata gcattagcat
    18721 tcccttgaac tgctgagaga acaccttctg tactattttg aatcacagct gttttggcag
    18781 tgttgtcaat ttttttatca ccgtcttttt tgagaatccc tgtgatttct gtgaaggcac
    18841 cccgtgttcc agagccattt tctcgtgaaa tcacctcaat cgttcctgaa gctgactgtt
    18901 tggaagcagc tgactgattg ccacaggcaa caagcccaaa tcctgataag ccaatggctg
    18961 caagagtaag catttttttg aatttcataa taatcacctt tatctctatg tatttttctt
    19021 gtgtaggctt actacattta tagtctaaca agtctttgta aaggtttatc cctgattcat
    19081 gtaaagattg tgtaaagaat caaaaaaagc cacttttgaa aaatggctgc tcctaaaaat
    19141 agctttaaaa attattagtc ctgtgcgaaa gattggttag gaagaaaaat cgtgaagcaa
    19201 ctgcctctgc caagctgact cgtcaccgtg acttggccac ctaataattg actgagttct
    19261 ttgacaatgg caaggccaag accagtgcca ccagtttgtc tgcttcgacc tttattaact
    19321 cggtaaaaac gttcaaaaat acgatcctgc tctaattgac taataccaat ccctgtatct
    19381 gatacagaaa tcttaatgcc ttcgttcacc ttttgggtct tgacctcaat ttttccccct
    19441 tgttcagtgt aacggatggc attggataaa agattgagta agatttggga aagtaattga
    19501 ctatctgata cgagggtgac atcatctggc acctgcacct ttagctgtaa atccttcttc
    19561 ttgagctgag gttgcaagct ttgagtcaaa tcctgtacaa attctgccaa agaaagggtc
    19621 gtccattgta taggcatttg ttgagcctta gataaggtaa gaagatgctc aacaatatgc
    19681 tcaagacgca aactttcttt gtaaataatg tctagaaagt catccttgag cgcttcttct
    19741 tcagctgaca tccccttaat ggtttcagca aagcccttaa tcgaagtaac tggtgtcctc
    19801 aattcatggg aggcatttga gacaaaggct aaatttaact tttcataagt tctaatcgtt
    19861 gttaaatcat atagcaagac gagcacagct tccacagatt gggtggggct aaaaacggga
    19921 actgctgtca cttctaaaat caagtcaccc tcatgaaacc cacttacttc ttgttttaac
    19981 cttgtttttt gatcaaaggc ttggtgaact aaattccgaa tatccatccg tttgaggtca
    20041 tcaagtgaac ttatgtcgcc gtccacatcg ggaaaataat gaggcagaga gcgactggat
    20101 aataacatct gaccttgagc ggaaactaaa aacgtcccca tggttaggtg cgacagaaga
    20161 acctccattg tttcggctag atccttgtat tgctgatcct gttgggagac tttggttttt
    20221 aggccagaca catactgagc caaagacttt aagtcttctt gccctttttc taaaaagtat
    20281 tcactactgg tcaagagagg ttggtgcaag gtctcaaaag caacttccca tttccaaagg
    20341 caaaagagcc agtagccacc tagtcccaaa gaaagggcta gaagaaagag accgatgcct
    20401 ttactgatcc aagttaatgc catccctgca atcagaatga ggctaacact tagattgact
    20461 agccaaaatt gaaggtagcg tttcatctat aactccttga acttataacc ataaccccga
    20521 atggttcgaa taaattgagg ggctttagga ttgtcttcaa ttttttccct caacttacca
    20581 atatgaacgt ccaccaaacg tgtttcctgc ccaaagtcat acccccagat acgttccaaa
    20641 agacgctctc tagtcagtgt catgttggga tgtttcataa gatagagcaa gagttcaaat
    20701 tcttttgggg tcaaactcag taacttattc gccttgtaga cttcatgacg ctcagggtat
    20761 actttcaagg tcccaaatag ccaagaatcg tcagcgatat tatctgaatc atctccttct
    20821 tgttctcctt tagttcgcct gaggacagcc ttgacacgcg ccagcaattc tctagggcta
    20881 aaaggcttgg tcaggtagtc atcagcccct aattccaagg ccaaaacctt atcaaattca
    20941 tcacttttcg cagaaaccat cataattgga gttttgacgc ctttggctct cagccgctta
    21001 caaacttcca tgccatctaa ttgtggtaac atgatatcaa gcaagataaa atcaaagggt
    21061 tctgtttctg ccaaagctaa ggccttccgt ccatttgtaa ccaattgagt agaaaagcct
    21121 tccttactta aatggtagtc aagcaatttc agaatgtgtt cttcatcatc cactaataag
    21181 acttgttttg tcatctatta tctcctattg gtaacattat aacacaatta tcagaaatcc
    21241 taacattgct aaatcagatt aaatttgcct atcaagacta gtatctggtc aaacgctcaa
    21301 tcatctcctt gtgctctgga taggtcgcca gtagatctac cctttcaaat aattcaaaat
    21361 cctcaaattc aaaaccagga gcaacaagac aagaaaccag agcatcatcc ttatcaactg
    21421 ttgatcccca aatagtgccc ttaggaacac agtagtgaag ttgttgccct ttggatatgt
    21481 ccaggcctaa agtgactgct tcgtagtgac catctgctgt aatcatgtga acagtaagtg
    21541 gggatcctgc atgaaaatac cagatttcat ctgctgtcaa tcggtgaaaa tgtgaaggat
    21601 tcgtttcttc taataagaaa taaatactgg tataaagcgc ccttccctta ccagcaaggt
    21661 ttatagtgtc tgaagctttt tttgtttgtc taaaatagcc accttcaata tggggagcta
    21721 actctagagt tcttatcaag tcttctttat ccgtcggagc caatgggttg aagtaactct
    21781 tgttcaaagt ggttttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat
    21841 tgatgcgacg gaagtacaaa tcaatcgccc taaaaaaaga attagcgaat tattctggta
    21901 aaaaaaatgc cacgctatga aggctcaagc gattgtcaca agtcaaggga gaattgtttc
    21961 tttggatatc gctgtgaact attgtcatga tatgaagttg ttcaaaatga gtcgcagaaa
    22021 tatcggacaa gctggaaaaa tcttggctga cagtggttat caagggctca tgaagatata
    22081 tcctcaagca caaactccac gtaaatccag caaactcaag ccactaacag ttgaagataa
    22141 agcctataac catgcgctat ccaaggagag aagcaaggtt gagaacatct ttgccaaagt
    22201 aaaaacgttt aaaatgattt caacaaccta tcgaaatcat cgtaaacact tcggattacg
    22261 aatgaatttg attgctggca ttatcaatca tgaactagga ttctagtttt gcaggaagtc
    22321 tattatttgg ttaggtgaat tagtgaagcg tttaggcaag tgtctctggt tacgacgtca
    22381 tggactctaa atcgattata tttaggggtc atgactagtg aagcacctag ccaaagtccg
    22441 aataggattt ggcgttagtt acttagattg ctttgcaatc aagtaacttt ggcgatttac
    22501 atcttctctg gcgcttctac tccaagcaag cgaagggctt ctttgagaac gactgcggtt
    22561 gcgtagctga gggctagacg gctgtcgcgt tctgggcttt catccaagat acgtgtatgt
    22621 gcatagtatt tgttaaagga ttgagccagg ctaattgcaa atttagcaat gatagaaggt
    22681 tcaaagttat ctgccgcacg gttgataata cgtgggaagt cttgaatgag tttaatgatt
    22741 tcccagcttt cagtatcatt caagctatag ttgccagctg tttctggttt gaaatcggct
    22801 ttgcgtaaga tagattggat acgagcgtag gcatattgaa cgtaaggtcc agtttcaccc
    22861 tcgaaggata ccatagcctc taggtcgaag tcgtatccat ttgtacggtc ggttttgagg
    22921 tcatagaatt taatggctcc aaccccaaca gcatgtgcta cctgatcttt attttccaat
    22981 tcaggatttt tagcctcgat ttggaccttg gcacggctaa cagcctctgc aacagtaggc
    23041 tctagcaaga tgacattccc tttacgagta gagagcttct tcccttcttt tgtaaccaag
    23101 ccaaaaggaa cgtgagtaat gtcgtcactc cagtcgtagc ccatctcttg caagacagct
    23161 ttgagctgtt taaagtgggc agattgttct tgaccaacga catagataga tttagcaaat
    23221 tggtattcgt ttttacggta aagggctgca gccaagtcac gtgtgatata gagagttgca
    23281 ccatcagact tcttgataag ggctggatgt tcaattccat atttctcaag attcacaact
    23341 tgggcacctt ctgattcaag aagtagtcct ttttcagaaa gaatgtctac aactgcatcc
    23401 atcttatcat tgtagaaggc ttctccgtta tagctgtcaa attcaacttt caattcattg
    23461 taaaggcggt taaattccac taaactttca tcgcggaacc attgccaaag agcgagagct
    23521 tcctcatctc cattttcaag tttacggaac cattcgcgcg cttcttcatc caagctaggg
    23581 tcattttcag cttcagcgtt gatgcggaca tagagtttaa ggagttcatc gattggatga
    23641 gcttttacag cttcttcgtc gccccatttt ttgtaggcaa caatcaacat cccaaattgt
    23701 ttaccccagt ctcccaaatg gttgaccttg accgtttgat aaccgatttt ttggaaaata
    23761 tgtgacaagc tatctccgat aacagttgaa cgcaggtggc caatagaaaa tggtttagcg
    23821 atattcggac tagacatgtc gataacaaca ttttcttgtt taccaatatt ttggtcagca
    23881 tagtgttctt tttcagtggt aacagcttgc aatacttgag cagaaatggt agatttatca
    23941 aggaaaaagt taacgtaagg tcctgttgcg acaacttttt caaaggcttg gctgttcatt
    24001 ttttcagcca gttcagccgc aatcatttgt ggtgctttac gttcgacttt ggcaagagaa
    24061 aaagcaggga aagcgatgtc ccccatttct gagtttttag gggtttccag taactttaaa
    24121 atagcctctt ggtccaggct atcaatgatg ctagccaatt cgcttgcaat caattctttt
    24181 gtattcatta agagctcctt tttggacttt tctactattt tatcacaatt ttaaagaaag
    24241 aagaaaaaat ttttgaaatc tcctgttttt ttggtataat atggttataa atatagttat
    24301 aaatatgcac gcaagaggat tttatgagaa aaagagatcg tcatcagtta ataaaaaaaa
    24361 tgattactga ggagaaatta agtacacaaa aagaaattca agatcggttg gaggcgcaca
    24421 atgtttgtgt gacgcagaca accttgtctc gtgatttgcg cgaaatcggc ttgaccaagg
    24481 tcaagaaaaa tgatatggtg tattatgtac tagtaaatgg gacagaaaag attgatttgg
    24541 tggaattttt gtctcatcat ttagaaggtg ttgcaagagc agagtttacc ttggtgcttc
    24601 ataccaaatt gggagaagcc tctgttttgg caaatattgt agatgtaaac aaggataaat
    24661 ggattttagg aacagttgct ggtgccaata ccttattggt tatttgtcga gatcagcacg
    24721 ttgccaaact catggaagat cgtttgctag atttgatgaa agataagtaa ggtcttggga
    24781 gttgctctca agacttattt ttgaaaagga gagacagaaa atggcgatag aaaagctatc
    24841 acccggcatg caacagtatg tggatattaa aaagcaatat ccagatgctt ttttgctctt
    24901 tcggatgggt gatttttatg aattatttta tgaggatgcg gtcaatgctg cgcagattct
    24961 ggaaatttcc ttaacgagtc gcaacaagaa tgccgacaat ccgatcccta tggcgggtgt
    25021 tccctatcat tctgcccaac agtatatcga tgtcttgatt gagcagggtt ataaggtggc
    25081 tatcgcagag cagatggaag atcctaaaca agcagttggg gttgttaaac gagaggttgt
    25141 tcaggtcatt acgccaggga cagtggtcga tagcagtaag ccggacagtc agaataattt
    25201 tttggttgcc atagaccgcg aaggcaatca atttggccta gcttatatgg atttggtgac
    25261 gggtgacttt tatgtgacag gtcttttgga tttcacgctg gtttgtgggg aaatccgtaa
    25321 cctcaaggct cgagaagtgg tgttgggtta tgacttgtct gaggaagaag aacaaatcct
    25381 cagccgccag atgaatctgg tactctctta tgaaaaagaa agctttgaag accttcattt
    25441 attggatttg cgattggcaa cggtggagca aacggcatct agtaagctgc tccagtatgt
    25501 tcatcggact cagatgaggg aattgaacca cctcaaacct gttatccgct acgaaattaa
    25561 ggatttcttg cagatggatt atgcgaccaa ggctagtctg gatttggttg agaatgctcg
    25621 ctcaggtaag aaacaaggca gtcttttctg gcttttggat gaaaccaaaa cggctatggg
    25681 gatgcgtctc ttgcgttctt ggattcatcg ccccttgatt gataaggaac gaatcgtcca
    25741 acgtcaagaa gtagtgcagg tctttctcga ccatttcttt gagcgtagtg acttgacaga
    25801 cagtctcaag ggtgtttatg acattgagcg cttggctagt cgtgtttctt ttggcaaaac
    25861 caatccaaag gatctcttgc agttggcgac taccttgtct agtgtgccac ggattcgtgc
    25921 gattttagaa gggatggagc aacctactct agcctatctc atcgcacaac tggatgcaat
    25981 ccctgagttg gagagtttga ttagcgcagc gattgctcct gaagctcctc atgtgattac
    26041 agatggggga attatccgga ctggatttga tgagacttta gacaagtatc gttgcgttct
    26101 cagagaaggg actagctgga ttgctgagat tgaggctaag gagcgagaaa actctggtat
    26161 cagcacgctc aagattgact acaataaaaa ggatggctac tattttcatg tgaccaattc
    26221 gcaactagga aatgtgccag cccacttttt tcgcaaggcg acgctgaaaa actcagaacg
    26281 ctttggaacc gaagaattag cccgtatcga gggagatatg cttgaggcgc gtgagaagtc
    26341 agccaacctc gaatacgaaa tatttatgcg cattcgtgaa gaggtcggca agtacatcca
    26401 gcgtttacaa actctagccc aaggaattgc gacggttgat gtcttacaga gtctggcggt
    26461 tgtggctgaa acccagcatt tgattcgacc tgagtttggt gacgattcac aaattgatat
    26521 ccggaaaggg cgccatgctg tcgttgaaaa ggttatgggg gctcagacct atattccaaa
    26581 tacgattcag atggcagaag ataccagtat tcaactggtt acagggccaa acatgagtgg
    26641 gaagtctacc tatatgcgtc agttagccat gacggcggtt atggcccagc tgggttccta
    26701 tgttcctgct gaaagcgccc atttaccgat ttttgatgcg atttttaccc gtatcggagc
    26761 agcagatgac ttggtttcgg gtcagtcaac ctttatggtg gagatgatgg aggccaataa
    26821 tgccatttcg catgcgacca agaactctct cattctcttt gatgaattgg gacgtggaac
    26881 tgcaacttat gacgggatgg ctcttgctca gtccatcatc gaatatatcc atgagcacat
    26941 cggagctaag accctctttg cgacccacta ccatgagttg actagtctgg agtctagttt
    27001 acaacacttg gtcaatgtcc acgtggcaac tttggagcag gatgggcagg tcaccttcct
    27061 tcacaagatt gaaccgggac cagctgataa atcctacggt atccatgttg ccaagattgc
    27121 tggcttgcca gcagaccttt tagcaagggc ggataagatt ttgactcagc tagagaatca
    27181 aggaacagag agtcctcctc ccatgagaca aactagtgct gtcactgaac agatttcact
    27241 ctttgatagg gcagaagagc atcctatcct agcagaatta gctaaactgg atgtgtataa
    27301 tatgacacct atgcaggtta tgaatgtctt agtagagtta aaacagaaac tataaaacca
    27361 agactcacta gttaatctag ctgtatcaag gagacttctt tgacaattct ccactttttt
    27421 gctagaataa catcacacaa acagaatgaa aaggagctga cgcattgtcg ctcccttttg
    27481 tctatttttt aaggagaaag tatgctgatt cagaaaataa aaacctacaa gtggcaggcc
    27541 ctggcttcgc tcctgatgac aggcttgatg gttgctagtt cacttctgca accgcgttat
    27601 ctgcaggaag tcttaggcgc cctccttact gggaaatatg aagctattta tagtatcggg
    27661 gcttggttga ttggtgtggc cgtaatcggt ctagttgctg gtggactcaa tgttgtcctc
    27721 gcagcctata ttgcccaagg agtttcatcc gaccttcggg aggatgcctt ccgtaaaatt
    27781 caaacctttt cttatgctga tattgaacaa tttaatgcgg gaaatctagt cgttcgaatg
    27841 acaaatgata tcaaccagat tcagaacgtt gtcatgatga ccttccaaat tcttttcaga
    27901 cttcccctct tgttcatcgg ttcgtttatc ctagcggttc aaaccttacc ttctctgtgg
    27961 tgggtgattg ttctcatggt agtcttgatt tttggtttga ctgctgtcat gatgggaatg
    28021 atggggcctc gttttgctaa atttcaaacc cttcttgagc gcatcaatgc cattgccaag
    28081 gaaaatttac gtggcgttcg tgtggtcaag tcctttgtcc aagaaaaaga gcaatttgct
    28141 aagtttacag atgtctcaga cgagcttctt ggtcaaaacc tttacattgg ttatgccttt
    28201 tcagtagtgg aaccctttat gatgttggtt ggttacgggg cggtcttcct ctctatttgg
    28261 ctggtcgcgg gaatggttca gtcggatccg tctgttgttg gttccatcgc ttcttttgtt
    28321 aattacctaa gccagattat ctttaccatt gttatggttg gatttttggg aaattctgtc
    28381 agccgtgcca tgatttccat gcgtcgtatt cgagaaattc ttgacgcaga gccagctatg
    28441 accttcaagg atatcccaga tgaagagttg gttggaagtc ttagctttga aaatgtgacc
    28501 tttacctatc caatggacaa ggaaccgatg ctgaaagatg tgagctttac tattgaacct
    28561 ggtcaaatgg ttggtgtagt tggagcgact ggtgcaggaa agtcaacttt ggctcaattg
    28621 attccacgtc tctttgatcc acaggacggg gccattaaaa tcggtggcaa ggatattcga
    28681 gaagtgagtg aaggaaccct gcgtaaaaca gtttccatcg ttctccaacg tgccattctt
    28741 tttagtggaa cgattgcaga taacttgaga caggggaagg gaaatgctac tctatttgaa
    28801 atggagcgcg cagccaatat tgcccaggct agtgaattca ttcatcgtat ggagaaaacc
    28861 tttgaaagtc cagttgaaga acggggaacc aatttctctg gtggacaaaa acaaaggatg
    28921 tcgattgcgc gtgggattgt cagcaatcca cgtattctga tttttgacga ttcgacctca
    28981 gccttggatg ccaaatcaga gcgcttggtg caagaagctt tgaataagga tttgaagggt
    29041 acgacaacca ttattattgc tcaaaaaatt agctcggttg tccatgcaga caagatcttg
    29101 gttctaaatc aaggacgatt gattggtcaa ggcacgcatg cagacttggt tgccaacaat
    29161 gccgtttacc gtgaaatcta tgaaacacag aaatgaaaga caaactataa gaaaagtcaa
    29221 tagttttatc taaactattt cttatttcaa tttgatgatt tggcgatgat tttagagcac
    29281 ggcaaaaacc cttgaaaaag tccatttttt caaaggtaat cctgtgttaa tttcagaaat
    29341 tacatcactt tttgttcgtc aaatggcagc tcttttttag gatataaaac agggttcgga
    29401 taagtttttt tgcaaggtgg atgatggcta cattgtaatg ttttccttgt tctaacttag
    29461 tcttaagata ggtcttgaaa gcaggtgaaa agcgagggca tgctttggca gcttgtatga
    29521 gcacctaccg cagatgaggg gaaccccgtt tgaccattct tcctgctaaa tcaatctgac
    29581 ctgactgata aatagaagaa tccagtccag cgaaagcttg taattgagca ggattatcaa
    29641 aggcatgaat atttcgaatc tcggctaaaa tgaccgcccc taaacgatcc ccaatcccag
    29701 taaccgtcgt gatgaccgag ttgaactcag ccatcaagtc attgacacat tttttcgcct
    29761 tgtcaatgag cctcttgtaa tgtttgatga tttcattaca cgagataaaa cgtctatgcg
    29821 ttatcaaact catgaccaat tgaaacaaaa agctgtggtt agatcctttc ggaaattgtc
    29881 aagcgattgg aggaaatgaa ctaatccaca gcggcttatt ccaagtatac cacttgggct
    29941 ttggcagtag ctaactgcgc taaatataat ataaggagga gtaaaatgaa gacagttcaa
    30001 tttttttggc attattttaa ggtctacaag ttctcatttg tagttgtcat cctgatgatt
    30061 gttctggcga cttttgccca agccctcttt ccagtctttt ctggacaagc ggtgacgcag
    30121 ctagccaatt tagttcaagc ttatcaaaat ggcaatccag aacttatatg gcaaagccta
    30181 tcaggaatca tggtcaatct tggcctgctg gttttggttc tatttatctc tagtgtaata
    30241 tacatgtgtc tcatgacgcg cgtgattgca gaatcgacca acgagatgcg caaaggtctc
    30301 tttggtaagc ttgctcagtt gacggtttct ttctttgacc gtcgacaaga tggcgatatc
    30361 ctgtctcatt ttaccagtga tttggataat atcctccaag cctttaacga aagcttgatt
    30421 caggtcatga gcaatattgt tttatacatt ggtctgattc ttgtcatgtt ttcgagaaat
    30481 gtgacgctgg ctctcatcac cattgccagc accccattgg ctttccttat gctgattttc
    30541 atcgtgaaaa tggcacgtaa atacaccaac ctccagcaga aagaggtagg gaagctcaac
    30601 gcctatatgg atgagagcat ctcaggccaa aaagccgtga ttgtgcaagg aattcaagag
    30661 gatatgatgg caggatttct tgaacaaaat gagcgcgtgc gcaaggcaac ctttaaagga
    30721 agaatgttct caggaattct tttccctgtc atgaatggga tgagcctgat taatacagcc
    30781 atcgtcatct ttgctggttc ggctgtactt ttgaatgata agtctattga aacaagtaca
    30841 gccctaggtt tgattgttat gtttgcacaa ttttcacagc agtactacca gcctattatc
    30901 caagttgcag cgagttgggg aagccttcag ttggccttta ctggagctga acgaattcag
    30961 gaaatgtttg atgcagagga ggaaatccga cctgaaaagg ctccaacctt cactaagttg
    31021 caagaaagtg ttgaaatcag tcatatcgat ttttcatact tgcctgataa acctattttg
    31081 aaagatgtca gcatttctgc ccctaaaggc cagatgacag cagttgttgg gccgacaggt
    31141 tcaggaaaaa cgactattat gaacctcatc aatcgctttt atgatgttga tgctggtggt
    31201 atttattttg atggtaaaga cattcgtggc tatgacttag atagtcttag aagcaaggtg
    31261 ggaattgtat tgcaagattc ggtcttgttt agcggaacga ttagagacaa tatccgattt
    31321 ggtgtgtcag atgctagtca ggaaatggtt gaggtagcag caaaagcaac ccacattcac
    31381 gactatatcg aaagtttgcc tgataagtac gatactctta ttgatgatga ccagagcatc
    31441 ttttcaacag ggcagaagca attgatttca atcgctcgaa ccctgatgac agatccagaa
    31501 gttctcattc tcgatgaagc aacttcaaac gtagatacgg tgacagaaag caagattcag
    31561 catgccatgg aggtggttgt agcaggtaga actagtttcg tcattgccca ccgcttgaaa
    31621 accattctca atgcagatca gattattgtc cttaaagatg gagaagtcat tgaacgtggt
    31681 aaccaccatg aacttttgaa gctaggtggc ttttattcag aactctatca caatcaattt
    31741 gttttcaaat aagaaagaag ttgtcctatg tgggcagctt tttcttgtcc ataaaaaatg
    31801 tttatcacag ccttaaaaaa aacatattag acgaaagtca ttttgagtga tatgatagga
    31861 ctatcgttag cattcgaaag gagaggcatc atggctagaa cggttgtagg agttgctgca
    31921 aatctatgtc ccgtagacgc agaaggcaaa atcattcatt catctgtatc ttgtagattc
    31981 gcagagatca ttcgtcaagt cggtggtctc cctttagtca ttcctgttgg tgatgagtca
    32041 gttgtacgtg attatgtgga aatgattgac aaactcattt tgacaggagg ccaaaatgtt
    32101 catcctcagt tttatggaga gaaaaagacc gtcgaaagcg atgattacaa tctggtccgt
    32161 gacgaatttg aattggcact cttgaaggaa gcgcttcgtc agaataaacc aattatggca
    32221 atctgtcgcg gtgtccaact tgtcaatgtt gcctttggtg gaaccctcaa tcaagaaatc
    32281 gaaggtcact ggcaaggact acctttcggg acatctcact ctattgagac agtagaagga
    32341 agcgtggtgg ctaagctatt tgggaaagaa agtcaggtca actcagtcca tcgtcaaagc
    32401 attaaagatt tggcacctaa tttccgtgta actgctattg attcaagaga ccaaactatt
    32461 gaagcgattg agtctatcga cgagcaccgc attatcggtt tacagtggca tccagagttt
    32521 ctggttaatg aagaagatgg caatttagaa ttatttgagt atttattgaa tgaactgtaa
    32581 cgattggaac atctggtcgt tctttctttt attttttcaa aatttttaga atgtggcatt
    32641 ttacgcaaac gtttgaattc tgataaaaat tggagaaatt cgacaaaaaa acttgaaaaa
    32701 aacgaaggta agcgttatga tagaaaagaa gaaatattgg aggaagaaca tgtcacatat
    32761 taaatttgat tattcaaaag ttttagacaa atttgttgca ccacatgaag tggaatacat
    32821 gcaatcacaa gtaacagcag cagatgaatt gatccgtaaa ggaactggtg ctggtagcga
    32881 cttcttggga tggttggacc ttcctgaaaa atacgatcgc gaagaatttg accgcatctt
    32941 gaaagctgct gagcaaatca agtcagacag cgatgttttg gttgtgatcg gtattggtgg
    33001 atcttacctt ggtgcaaaag cagcaatcga cttcttgaat caccattttg ctaacttgca
    33061 aacaaaagaa gaacgcaaag ctccacaaat cctttacgca ggaaactcaa tatcatctac
    33121 ttaccttgct gacttggtag agtatgttgc agacaaagac ttctcagtaa acgtaatttc
    33181 taaatcaggt acaacaactg aaccagcgat tgctttccgt gtctttaaag aactcttggt
    33241 taagaaatac ggtcaagaag aagctaacaa acgtatctat gcaacaactg accgccaaaa
    33301 gggtgctgtt aaggttgaag cagacgctaa cggttgggga acatttgttg ttccagatga
    33361 tatcggtgga cgcttctcag tattgacagc cgttggtttg cttccaatcg cagcatcagg
    33421 agctgacatc aaagctctta tggaaggtgc gaatgcagct cgcaaagact acacttcaga
    33481 caaaatctct gaaaacgaag cttaccaata cgcagctgtt cgtaacatcc tttatcgtaa
    33541 aggctatgca actgagatct tggtaaacta tgagccatca cttcaatact tctcagaatg
    33601 gtggaaacaa ttggctggtg aatcagaagg aaaagaccaa aaaggtatct acccaacttc
    33661 agccaacttc tcaactgact tgcactcact tggtcaattt atccaagaag gaactcgtat
    33721 catgtttgaa acagttgtcc gtgttgacaa acctcgtaaa aacgtgctta ttcctacttt
    33781 ggaagaagac cttgacggac ttggttacct tcaaggaaaa gacgttgact ttgtaaacaa
    33841 aaaagcaact gacggtgttc ttcttgccca cacagatggt gatgtaccaa acatgtatgt
    33901 gactcttcca gagcaagacg ctttcactct tggttacact atctacttct tcgaattggc
    33961 aattgccctt tcaggttact tgaatgctat caacccattt gaccaaccag gtgttgaagc
    34021 ttataaacgt aacatgtttg cccttcttgg aaaaccagga tttgaagaat tgagcaaaga
    34081 acttaacgca cgtctataat agaagaaaag agtggtttgc ccactctttt tactctcttt
    34141 atccatagaa attggactca gccaagactt gtgatataat atagaaagca aaaaggcaga
    34201 cgcctagata ataggagaaa ctatgtcaaa agatatccgc gtacgttacg caccaagtcc
    34261 aacaggacta ctacacatcg gaaatgctcg tacagcattg tttaattact tgtatgcgcg
    34321 ccatcatggt ggaacatttc tcatccgtat cgaagatact gaccgtaaac gccatgtcga
    34381 ggatggtgaa cgttcacaac ttgaaaacct tcgctggtta ggcatggatt gggatgaaag
    34441 tccagaatca catgagaatt atcgccagtc tgagcgtttg gacttgtatc aaaaatacat
    34501 cgaccaacta ttagctgaag gaaaagccta caaatcttac gttacagaag aagagttggt
    34561 agctgaacgt gaacgtcaag aagtagctgg cgaaacacca cgctacatca atgaatacct
    34621 tggtatgagt gaagaagaaa aagcagctta catcgcagaa cgtgaagcag cagggatcat
    34681 cccaactgtt cgtttggctg tcaatgagtc aggtatctac aagtggcatg atatggtcaa
    34741 aggcgatatc gaatttgaag gtggcaatat cggtggtgac tgggttatcc aaaagaaaga
    34801 cggttaccca acttacaact ttgccgttgt tatcgatgac cacgatatgc aaatctctca
    34861 tgttatccgt ggagatgacc atattgctaa tacaccaaaa cagcttatgg tctatgaagc
    34921 tcttggttgg gaagctccag agttcggtca catgaccttg attatcaact ctgagactgg
    34981 taagaagtta tctaaacgtg atactaatac acttcaattt atcgaagatt accgaaagaa
    35041 aggttacctt ccagaagcag tctttaattt tattgctctt cttggttgga acccaggtgg
    35101 tgaagatgag attttctctc gtgaagaact cattaaactt tttgatgaaa accgcctcag
    35161 caagtcacca gcagcctttg atcagaaaaa actagactgg atgagcaatg attatatcaa
    35221 gaatgcagac cttgaaacca tctttgaaat ggcaaaacca ttcttagagg aagcaggccg
    35281 tttgactgac aaggctgaaa aattagttga gctctataaa ccacaaatga aatcagtaga
    35341 tgagattatc ccattgacag atcttttctt ctcagatttc ccagaattga cagaagcaga
    35401 gcgcgaagtc atgacgggtg aaacagttcc aacagttctt gaagcattca aagcaaaact
    35461 tgaagcgatg acagatgata aatttgtgac agaaaatatc ttcccacaaa ttaaagcagt
    35521 ccaaaaagaa acaggtatta aagggaaaaa tcttttcatg cctattcgta tcgcagtttc
    35581 aggcgaaatg catgggccag aattaccaga tacaattttc ttgcttggac gtgaaaaatc
    35641 aattcagcat atcgaaaaca tgctaaaaga aatctctaaa taaagaggat acaataatgg
    35701 acatctggga aaagatgtac gaagaagcac agaaactata caatccacat gaagtatcag
    35761 actttgttta tgccaatcat gttgtagctg cagtagaagc agaagatgga caaatattta
    35821 caggattctg tatggaggga acctgtggtg ttttccatct ctgcgcagaa cgggcggccc
    35881 tcttcaatat gtaccaattt tcaggacaaa ctaaggttaa gaaagtatta gcctttcgag
    35941 ataaaccacc ttatggtgga agttcagcca tgccttgcgg tgcttgtaga gaattccttt
    36001 tagagcttaa tgctgaaaat aaagatgcag aattcatgat ggactataat ataagaaaaa
    36061 cagttaaagt cgcagaacta atcccttatt ggtggggaga agaacgtgct tctaagttta
    36121 atgagcgata gaagagtcag tataattctg gcttttttta ctataagttg aaaaaataaa
    36181 aaaagtttaa aaaagt
//
LOCUS       DAVDHC010000020        33471 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVDHC010000020 DAVDHC010000000
VERSION     DAVDHC010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.020"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..422)
                     /locus_tag="VUR43_001366"
     CDS             complement(<1..422)
                     /locus_tag="VUR43_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5413044.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYNFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLTISTSTVIRKLND"
     gene            847..1236
                     /locus_tag="VUR43_001367"
     CDS             847..1236
                     /locus_tag="VUR43_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5413045.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            1202..1516
                     /locus_tag="VUR43_001368"
     CDS             1202..1516
                     /locus_tag="VUR43_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413046.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            2200..2361
                     /locus_tag="VUR43_001369"
     CDS             2200..2361
                     /locus_tag="VUR43_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413047.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            2453..2980
                     /locus_tag="VUR43_001370"
     CDS             2453..2980
                     /locus_tag="VUR43_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET5413048.1"
                     /translation="MSKEKIKVYFYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKQGKENGMV
                     ALLRMDINLKTASCL"
     gene            2971..4131
                     /locus_tag="VUR43_001371"
     CDS             2971..4131
                     /locus_tag="VUR43_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET5413049.1"
                     /translation="MFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQN
                     GKNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEA
                     IVSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKK
                     DGTKYKDFYYYGYKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQE
                     KINMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLY
                     RMYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISA
                     LISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            4399..4965
                     /locus_tag="VUR43_001372"
     CDS             4399..4965
                     /locus_tag="VUR43_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413050.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            5287..5475
                     /locus_tag="VUR43_001373"
     CDS             5287..5475
                     /locus_tag="VUR43_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET5413051.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            5537..6295
                     /locus_tag="VUR43_001374"
     CDS             5537..6295
                     /locus_tag="VUR43_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET5413052.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            6353..6814
                     /locus_tag="VUR43_001375"
     CDS             6353..6814
                     /locus_tag="VUR43_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET5413053.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            6848..7207
                     /locus_tag="VUR43_001376"
     CDS             6848..7207
                     /locus_tag="VUR43_001376"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET5413054.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            7319..8203
                     /locus_tag="VUR43_001377"
     CDS             7319..8203
                     /locus_tag="VUR43_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET5413055.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKQGILA
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            8366..10105
                     /locus_tag="VUR43_001378"
     CDS             8366..10105
                     /locus_tag="VUR43_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HET5413056.1"
                     /translation="MELSAIYHRTESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            10380..10682
                     /locus_tag="VUR43_001379"
     CDS             10380..10682
                     /locus_tag="VUR43_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413057.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            10738..11166
                     /locus_tag="VUR43_001380"
     CDS             10738..11166
                     /locus_tag="VUR43_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5413058.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            11224..11833
                     /locus_tag="VUR43_001381"
                     /pseudo
     CDS             11224..11833
                     /locus_tag="VUR43_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
     gene            12115..12362
                     /locus_tag="VUR43_001382"
                     /pseudo
     CDS             12115..12362
                     /locus_tag="VUR43_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            12467..12769
                     /locus_tag="VUR43_001383"
                     /pseudo
     CDS             12467..12769
                     /locus_tag="VUR43_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            12925..14154
                     /locus_tag="VUR43_001384"
     CDS             12925..14154
                     /locus_tag="VUR43_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET5413059.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            14174..16870
                     /gene="ppc"
                     /locus_tag="VUR43_001385"
     CDS             14174..16870
                     /gene="ppc"
                     /locus_tag="VUR43_001385"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET5413060.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    16953..17170
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17283..18287
                     /locus_tag="VUR43_001386"
     CDS             17283..18287
                     /locus_tag="VUR43_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET5413061.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            18356..19222
                     /locus_tag="VUR43_001387"
     CDS             18356..19222
                     /locus_tag="VUR43_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5413062.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            19219..19977
                     /locus_tag="VUR43_001388"
     CDS             19219..19977
                     /locus_tag="VUR43_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5413063.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            20067..21827
                     /gene="dnaG"
                     /locus_tag="VUR43_001389"
     CDS             20067..21827
                     /gene="dnaG"
                     /locus_tag="VUR43_001389"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET5413064.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYQAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEEFERLISQKRRME"
     gene            21830..22939
                     /gene="rpoD"
                     /locus_tag="VUR43_001390"
     CDS             21830..22939
                     /gene="rpoD"
                     /locus_tag="VUR43_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET5413065.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            22953..23282
                     /locus_tag="VUR43_001391"
     CDS             22953..23282
                     /locus_tag="VUR43_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET5413066.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            23397..24440
                     /gene="cpoA"
                     /locus_tag="VUR43_001392"
     CDS             23397..24440
                     /gene="cpoA"
                     /locus_tag="VUR43_001392"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET5413067.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            24456..25781
                     /locus_tag="VUR43_001393"
     CDS             24456..25781
                     /locus_tag="VUR43_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET5413068.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRIIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            25812..25988
                     /locus_tag="VUR43_001394"
     CDS             25812..25988
                     /locus_tag="VUR43_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET5413069.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            26047..26181
                     /locus_tag="VUR43_001395"
     CDS             26047..26181
                     /locus_tag="VUR43_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET5413070.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            26245..27555
                     /gene="obgE"
                     /locus_tag="VUR43_001396"
     CDS             26245..27555
                     /gene="obgE"
                     /locus_tag="VUR43_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET5413071.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYSRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYKLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            27565..27723
                     /locus_tag="VUR43_001397"
     CDS             27565..27723
                     /locus_tag="VUR43_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413072.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            28732..29991
                     /locus_tag="VUR43_001398"
     CDS             28732..29991
                     /locus_tag="VUR43_001398"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET5413073.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            30007..30558
                     /locus_tag="VUR43_001399"
     CDS             30007..30558
                     /locus_tag="VUR43_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5413074.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            30551..31828
                     /locus_tag="VUR43_001400"
     CDS             30551..31828
                     /locus_tag="VUR43_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET5413075.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKIMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            31844..32704
                     /locus_tag="VUR43_001401"
     CDS             31844..32704
                     /locus_tag="VUR43_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET5413076.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            33083..33471
                     /locus_tag="VUR43_001402"
                     /pseudo
     CDS             33083..33471
                     /locus_tag="VUR43_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT        10927 a         5314 c         7288 g         9942 t
ORIGIN      
        1 aagtcattga gcttacgaat aacagttgaa gttgaaatgg tcagctgatg ggcaatatca
       61 gtcatagaaa ttttttcaat taacttttga gcaatttttt ggttgatgat acgagggatt
      121 tggtgatttt tctttaccag gggagtctca gcaaccatca tttttgaaca gtgatagcac
      181 ttgaaacggc gttttctaag gagaattcta gaaggcatac cagttgtttc gaggtaaggg
      241 atcttagacg gtttttgaaa gttatatttc ttcattagac ttccacaatc agggcaagat
      301 ggagcctcat aatccagctt agcgataatt tctttgtggg tatccatatt gatgatatct
      361 agaatcttga tgtttgggtc tttaatatcg agcagttttg tgataaaatg taattgttcc
      421 atatgaatct ttctaatgat ggttttgtcg cttttcatta taggtcatat gggacttttt
      481 ttctacaaca aaataggctc cataatatcc ataggggatt tacccactac aaatattata
      541 gagccgtttt ttaatggcaa atacagcaca gaatttaaga taaaattagt aaaagaatat
      601 catgaatgaa aaataggata tagagaataa cagcaatatt aaaaagatca ggactgataa
      661 taaacaaaaa gaaagtacaa cgactagttc aaaagctaaa acttcaagta aaaagttatt
      721 caagaaaatc tagaaaatac tcatcctaca aaggacaggt aggaaaaata tcagacaaca
      781 aaataaaaag aaatatttat taccgaaaaa aaggggaaat cgagtcaagt accaacaggc
      841 tcatctattc caaaaagata tttactcgat ggaaaaactc ctagaattag tgctacaaat
      901 attgacaatg gtatcttagg ttactacgaa gatatagatg ataaaaatta tagagttttt
      961 gaaaatttta tatctgtttc atttttagga gcagtctttt atcataaata taaagcaagc
     1021 ctagatatga aaattcattg tttaaaatta aaaaataaag aattgaataa agaagtagca
     1081 ttctatttaa cttcaattat taggcaagct ttaaaaaata ctgaatataa agatcaaata
     1141 tctagcacag tattgccaga tatcaaaatt aaattaccga tagacagtag aggtactcca
     1201 gattggaatt acatggaaag atatagagat agataaagag agagagggag agatagataa
     1261 aaagtccacc cccatttttt atggagaatt caaaaatgta aggttaagca aagaagaata
     1321 taaaaatcta aaagaaaaat taaactcaca cacagatata atgataaata aactatccag
     1381 atacatggaa agcagtggta agacctatca aaaccactat gtgacaatct taaaatggta
     1441 tgaagaagat aaagacaaac taagacagaa aggtttaaat aaaaaaatga attatgatgt
     1501 aggagaatct ttatagataa aaagaggtgg aaaggcacta ttaaagactt taagtctaaa
     1561 aaggtatcaa agtatgccag agataaaaaa atataaatat gacactttaa aggcgattag
     1621 aaaattaaag aaatgctaga agacttttag atgacagtta ccaagagggt ctaattttca
     1681 ctgctactta tgcagtggga attggacctt tttatataag caaattctat ttcaaaattg
     1741 gttaccaaga aagacttctt ttcactgtta agtataagag ggtaatttat agaattttgt
     1801 tacatcaaga taaatatttt ctgatggtca aattttaaaa agattaataa ctctcgataa
     1861 attttgaacc ttaacaattg aatagaccaa gacaagacgt taattatttt tggagcgtaa
     1921 taacctatcc gtcaagatct ttcggctgaa taattcggca aaaaaagttc tgctaagcaa
     1981 aaagaaagtg agcgataagt aagagtttga atatagggag ggatacccta tccgctatga
     2041 agaaaatgag ggtaatgata cttctaaggt tgaagccggc tcatccggaa tagaggcgga
     2101 ggtgagattc ctatgttgct aatccaaagc acttgtcaat gtcaaaaaac ttaattaaac
     2161 aaataattat tagatataaa actttagagg aggtatatat tggacaatga ctggaatgga
     2221 ttggctgatt taatagcaaa tctgattgca aaatatgctg gtgctttaga tttagataat
     2281 ctacccgatc caacgccagc aaaaaatcaa gagatgaaaa atagttttga catggcaaaa
     2341 acacaaattg agacggacta ataaaagtgt tataatatac ttgaaatgat agtccaaact
     2401 taaattaaaa aaattatata tgatatagaa aaattatatt gaggttaata ctatgtcaaa
     2461 agaaaaaata aaagtatact tctatacacg agtatctacg tcaatacaga tagaggggta
     2521 ttcgttagag gcacaaaaat cacgaatgaa agcttttgct atttacaacg attatgaaat
     2581 tgttggagag tatgaagatg ccgggaagtc tggcaagtct attgaaggta gaatacagtt
     2641 caatcgaatg atggaagata taaaatctgg aaaagatgga gtatcttttg ttcttgtgtt
     2701 taagttatca agatttgcaa gaaatgccgc tgatgttctt tctacacttc agataatgca
     2761 ggattatgga gttaatctta tctgcgttga agatggcatt gattcatcta aagatgctgg
     2821 gaaactaatg atttctgttt tatcagctgt ggctgaaata gaaagagaaa acatccgtat
     2881 tcaaacaatg gaaggtcgca ttcaaaagca agggaaggaa aatggaatgg tggctttgct
     2941 ccgtatggat ataaacttga agacggcaag ctgtttataa atgaggaaga ggcagttgca
     3001 ataagaacga ttttcgacca gtatgtaaat actacgatag gagccaatgg gatatctaaa
     3061 tacttagaga atcatggaat tagaaaaatc ccaagacaga atggtaagaa tcctttgttt
     3121 gatgcaggtc ttataagaaa gatattaaag aatcctgtat ataatgggaa aatagcattt
     3181 ggaagaagaa ctttagaaaa agttcatggt acaagaaatg aatataagca ggttgaacaa
     3241 gatgaatatc taatatctga agggatacat gaagctatag tttccgatga agtttggcaa
     3301 gctgctcagg ttaagctaaa atctcaagca aagaaatatg agcatgtgaa taaaggaaaa
     3361 gatacacgca cacacttgct ttctggaatt gtaaaatgcc cgatatgtgg agtgggaatg
     3421 tttgggaaca agtgtatcaa gaaaaagaaa gatggcacaa agtataaaga tttttattac
     3481 tatggttata aacataggca gatgataaga ggtcataagt gtacattcag taagcaaatt
     3541 agagaagaat tgttagatga tgctgttgca gaggtgattg tcaagatagt aagtaatccg
     3601 aaatttgctt ctatgatgca agaaaaaatc aacatgaagg tggatacctc tgaaatagaa
     3661 aaagaaatag ataattacca aaaggaattg agaaagagtc attctacaaa gtttaagcta
     3721 attgaggaaa tagataattt agatgttgaa gataagcatt ataagagaag gaaacaggat
     3781 ttagatgata gactatatcg tatgtatgac aaaatagatg aattagaatc atcactaatt
     3841 gatgcgaaag caaagaaaca gactattgaa gctgaaaagc ttacaggaga taacatatat
     3901 aaggttctga tctattttga taagctctat aaagtcatga atgatgtaga gcgtaggcag
     3961 ttaatttcag ctttgatttc tgaaattcaa gtttatgaag aaaaacaatc taacggacaa
     4021 tggctaaaat ccattacttt taagctacca attatagaag aaaatctcaa cataggtttg
     4081 gacaatgatg aacaagttga atgtgtaagt ttattagaga aacgtagtta atcctcaaaa
     4141 ggttccccga accttttgag tcccactgac gcatcacgct gaggcggtat cactgcttgt
     4201 acgagttgaa gcatcagcga agtaaaagta gatgttcagc caatgcgacg aggtgagacc
     4261 gaaggtcgat aaggtgtgtt ctgggtatag gactcgtaaa gtaagtagga aatatgatga
     4321 gatgatacag agagcctgaa ttggtcaggt gacgtgctta tttacattag cctgataatg
     4381 aaaatggaga gattatcgat ggttatattg gaattgtacc aaaatgatta ttctaaagat
     4441 ttagtagcat ttgattccat agaagatggg aaagcctttg tagctcaaat cccgggatac
     4501 actctggaaa cagaagatgg ttttgaagtg gagtatttta atcctaaaaa cataccggat
     4561 tatatggaaa ttatttttaa cggaaatatt gttcctttat ctaaatttat gttcgatcct
     4621 gaggaaaatg taaacattat ttggaaagag atttcaaatt tatccctcaa aaatgataga
     4681 gtgatcgaag gatattcaaa aattgatgca tatgtcgtta acaaccatga agttaaagcc
     4741 tatgtcgaaa caagagaaac gaactatcgt aaagcaaaag acttcttaga aagccgcgga
     4801 tatgaaatcg acagaagctt tttcggaagt gaagacggtg aagcgattct ttacagaaaa
     4861 aaagggatcg aagtttggca tttcttgtgt cacttagacc caatgtttgt agagattgaa
     4921 gatgtagaag gatatgttaa agaagaagtt ggagagattc aatagtcaac caaagttcct
     4981 tgtgagtata tacctttgct agtaaaagag tcaaaacgtt ataacgaagg ggggtaagaa
     5041 aacccttgag tgtaagtctt tttcttgttt agagggaaag tattagagta gccgctcata
     5101 atttatacta gatttgataa ctgatttgag acagatttta tttctataaa tattgtgaaa
     5161 attttttaat accaaagatt taaagttact gtgttaaaaa tcctctccac ttttaaacta
     5221 atgtattata aaagccagtt gacacaagtg ttacacctgt gatagaatta acttgaggtg
     5281 atgaaaatgg caaccgataa aaatagaata atgattagct tggatgataa aaatctagag
     5341 aaacttgaaa atttagtaga agatgctaga gatagaaggg gaatgcgact aacaaagtcc
     5401 caggttattg aattactcct aaataccgtt gattatttcg atgatattat gggggctatt
     5461 tactcaaaaa aataagagca aaattgctat tattttttac aaattggtgt aacactagtg
     5521 atataggagt gatgaaatgg ttgtttatat tagacaaagt aaattaccaa gtgaggtttc
     5581 aattaataaa tacaatgctc aagtaggtgc ctacttacaa ggagaagaag ctgttttata
     5641 tcaatctttt tctgaaataa aagagttaac aagtgaagat atagttgtag attatataat
     5701 ggagactaga gcattactaa aaatgatggg cttaaacgtt ccggttcatg actatcctat
     5761 tgagcttaaa gagttttatg gtcgaaagat ttatgctggt attttaggag agattgtgaa
     5821 tatacctgat aattggggaa aatttattaa gcctaaagct ggttcaaaag tctttactgg
     5881 aagagttgtt aatggaaccc atgatttaat aggtattggt ctacctttcg actatcctat
     5941 atggattagt gaggttgtag aattcatagc tgaatggcgt tgttttgtgt tagatggtcg
     6001 cgtattagat gttcgaccct atacaggtga ttatcatgca caatttgatg caagtgtaat
     6061 tgatgaagcg atatcatgtt ggaaagatgc gccaatagct tatggactag atatcggtgt
     6121 tactcgcgat ggcagaacac ttgttgttga agtaaatgat ggttatgcat tgggaaatta
     6181 tggcctatct cctttaaaat caatcaattt tcatagagct aggtggaaag aaatggtaaa
     6241 accctatttt gaaaaaaatg aaatttttaa aatccaacag gatgttgttt tctaaaataa
     6301 atatggtata taaccaatat aaaaagcatc aaaatgaaca aggaggaatc tgatgcttgg
     6361 agcaattatt ggagatattg tcggttctgt ttacgaatgg aacaatatca aaacaaagga
     6421 ctttccttta tttcggaagg actgcttttt tacagatgac acggttatga cctgtgctgt
     6481 tgcagaagca attatgaatg gtggacaaaa agacgacttc attgacgcga tgaagaaata
     6541 tggcagaatg tatccgaatg ctgattacgg tgctcggttt aatgcatggc taaacagcga
     6601 taaccgtgag ccttataata gctttgggaa tggatcagct atgcgtattt ctccatgtgc
     6661 ttggatcatg gactgtggtt tttatgcgaa aactggtata tggccatcat ctagaggact
     6721 tacgagtctt tctgcagagg taactcataa tcatccagaa ggtgtcaaag gcgctatggc
     6781 tacagctgat gctatctttc tatgtcgttt ttaatttggt ggttattgta gagagtacga
     6841 gtaatcaatt aacgacaatc ctatagagtg taaaagacga attaaggatt atatagaaaa
     6901 agaatacgat tacaatctat ctcaaacttt agatgaaatc cgtcctaact atcgttttaa
     6961 cgaaacatgt caggaaactg tccctcaagc cattatcgcc tttcttgaaa gtagagactt
     7021 cgaagatgcg ataagaaatg ccatctcact tggtggcgac agtgatactc tcgcagcaat
     7081 cacttgtagc atagcagagg cagcttacgg tattcctgat tggatcaagg ataaggccta
     7141 ttcttacttg gatgaaccct taaaggatgt agttaggcga tgggaaaata gaataaaagt
     7201 gtattaatct ccagtacgtc agatttctct tttctgtatt ttcattgtat aataggatta
     7261 catttacttg catacgacga aatgtaaaca tttctattta aaattaagga taaaatcaat
     7321 gaaaaaagca atggtaatta tcaaccctac ttctggtggc gagaaggctt tggattacaa
     7381 agaaaagctg gagaataaag caaaagaata ctttgaatat gttgaaacca aaattaccga
     7441 aaaagcgctg gatgcaacac attttgctga agaagcttct cgtgagcagt atgatgcagt
     7501 ggttgtgttt ggtggagatg ggactgtcaa tgaagtcatt tcaggtattg atgagagaga
     7561 ctacattcct aagttaggga ttatcccagg cggtacgggt aacctcatta caaaactttt
     7621 ggaaatcaat caagacatcg atggcgcaat tgacgaactg gattttgatt taaccaataa
     7681 gattgatatc ggtaaagcaa atgacaacta ttttggttat atctttagta tcggttctct
     7741 gcctgaggcg attcacaatg ttgaaataga ggacaaaaca aaacaaggta ttttagccta
     7801 tgctgtaaat actatgaagt ctgtcatgac agatcaggtc tttaacatta aggttgagac
     7861 agaaaatgga aattatgttg gtgaagctag ccatgttttg gtccttttga caaattactt
     7921 cgctgataag aaaatctttg aagaaaacaa ggacggctat gccaacattt tgattctgaa
     7981 agatgcctct atattctcca aattatccgt cattcctgat ttattaaaag gggatgttat
     8041 cgcaaatgat aatatcgagt atatcaaagc gcgtaatatt aaaatctctt cagatagtga
     8101 attggagtca gatgttgacg gagataaatc agataaccta cctgtagaaa tcaaagtcct
     8161 agctcagcga gtagaagtat tttcaaaacc gaaagaggat tagtatatag agaaagcctt
     8221 ttttaaggct ttttgtatac tttaaaagat agttccttta acaacggaca ttccttgcaa
     8281 atagttcaca aaaatagtat actggattca ttgagtttga aaacgtttgc gtaaaatttg
     8341 aatgaatact ttaggagata aattgatgga attgagtgct atttaccata ggactgagtc
     8401 ggagtatgcc tatctttata aggataagaa actccatatt cgaattcgaa ctaagaaagg
     8461 ggacattgaa agcatcaact tgcactatgg ggaccctttt atctttatgg aggagtttta
     8521 tcaggataca aaagaaatgg tcaagataac ttctggtacc ttatttgacc attggcaggt
     8581 tgaagtgtca gttgactttg cacgtatcca gtatcttttt gagctcagag atacagaagg
     8641 tcaaaatatt ttgtatggcg ataaagggtg tgtggaaaat tctctagaaa atcttcatgc
     8701 aattgggaat ggatttaagt tgccttatct tcatgagatt gatgcctgca aggttcctga
     8761 ctgggtttca aatacggtat ggtatcagat atttcctgaa agatttgcca atggcaatgc
     8821 tctattaaac ccagaaggga ctttagactg ggattcatct gtcacaccta agagcgatga
     8881 tttctttggt ggtgatttac aggggattat tgatcatatg gattacttgc aagacttggg
     8941 tattactgga ctatatcttt gtcccatctt tgaatctaca agcaatcaca agtacaatac
     9001 gacagattac tttgaaattg accgtcattt tggagacaag gagacctttc gggaactggt
     9061 ggatcaagcg catcatcgtg gcatgaaagt catgctggat gcggtattta atcatattgg
     9121 ttcgcaatct cttcaatgga aaaatgtcgt caaaaatggt gaacagtctg cttataagga
     9181 ttggttccat attcaacaat tcccagtgac aactgaaaag ctagttaata agagagactt
     9241 accctatcat gtttttggtt tcgaggacta tatgcctaag ctaaatacag ccaatccaga
     9301 ggtcaagaat tatcttttaa aggttgcgac ttattggatt gaagagttta atatcgatgc
     9361 ttggcgtttg gatgtggcta atgagattga ccatcagttc tggaaggatt ttcgtaaggc
     9421 agttttagct aaaaatcctg atctttatat cctaggagaa gtctggcata catctcagcc
     9481 ttggctaaat ggagatgagt tccatgccgt catgaattat cctttatctg atagtatcaa
     9541 ggactatttc ttacgaggaa ttaagaagac agaccagttc atcgatgaaa tcaatggaga
     9601 gtctatgtat tacaagcagc agatttcaga ggtcatgttt aatctcttgg attcacatga
     9661 tacagagcga atcctgtgga cggccaatga agatgttcaa ctggttaaat cagccttagc
     9721 ctttctcttt ttacaaaaag gaacaccgtg catttattac ggaaccgagc tagccttgac
     9781 tggaggacca gatccagatt gtcgtcgttg tatgccttgg gaacgtgtat caagtgacaa
     9841 tgatatgctg aactttatga agaggctgat taagattcgg aaatacgcgt cagtaatcat
     9901 ttcgcatggc aagtatagcc ttcaagaaat caaatctgat ctagtagctc tggaatggaa
     9961 atacgaagga cggatcctca aagcaatatt caaccaatca acagaagatt atcttttaga
    10021 gaaagaagca gtagcactag caagcaattg ccaagaattg gagaatcagc ttgtcatctc
    10081 tccagatgga tttgtgattt tctaaaaact agttgatgaa gattatggta catttcatat
    10141 cttatatagt ataataaggc tagttactaa acttgtaaag gagaacttaa atgaattgta
    10201 gaggacatga aacaagacaa agaattgtta gagattttga agtttagcct aaagcacata
    10261 ttaagctgtt agcaaatcaa caaaaacata gtgatgcagg agcaactatt gaagatgaat
    10321 attatgtatt tatcgctgag agtaaaattg atggcaagaa ggaagttatt cagtgttgca
    10381 tgggtgcggc aagggatttt ttagaactaa ttaatcacaa agggctacct ctttttaatc
    10441 cgcttgtagg tgattctcat gtaaataata gacaagaata tgacaataca gggagtggaa
    10501 atttacaacc tgaaaagtgg aatgaaactg caaagcagct ttataatgtt ataatgtggt
    10561 tgattatttt atggaatgct aagccggata cacctttatt taattttaaa gacgaagtaa
    10621 ttaagtataa aacatatgag ccttttgaaa gcagtataaa attggtatca atcaatgagt
    10681 aacaaagtat cagcatgatt cgaaacattt acttgtaatt tgcggaggaa catcaatatg
    10741 gatggaataa caaaagattt tataaaaacg gctaaactaa tgaaacaatt atggccccaa
    10801 ttgaccgata aagaagctat tgatgaagta aaaaaatata cgaatggcaa aaatactgca
    10861 atctttactg aagttgaagg tgacacaatt gtaggtctag cactatgttc actcagattt
    10921 gattatgttg aaggttgtaa atatagtcct gttggattct tagaagggat tattgttgac
    10981 gaggaatatc gtttaaagga tattgctaaa aatctctgta caaaatgtga ggaatgggcg
    11041 aaaaataaag gatgtaagga atttgcaagt gactgtactt taacgaatac ggattctata
    11101 agatttcatc tcaatattgg atttcaggag gcaaatagaa ttattcattt taagaaaaaa
    11161 ttataattta gaaacgtgaa taaacttgtt taaactttat gtatctttag aaagtgtgtt
    11221 aacttgaaag aacaaatttt tttgatgggt gggaatcccc caatgaagaa atatagtatt
    11281 gttgataaaa ttgtattatc aaccaagatt aaaagaatta tcatttttac agtttttcga
    11341 gaaaattggg aaccgtacat gaaaaagtac acggaagttt ttcaaagtca atttcctaat
    11401 ctaaacattg attacttgct cctggacact gagcagattg atcttgatag ctatctagat
    11461 gctgacataa ttatcatcgg tggtggaaat acggaaaaat atattgctaa cttatgttaa
    11521 tcaggagttc aaaagttata tcgatcatat gcttaataaa gaggcaaaaa ttataggatt
    11581 ttctgcagga gccctactat taggagaaaa agtctatgtc tcacctaatg ataattcaga
    11641 tcatcagata aagataaaaa atggattagg actctttagt cagtttttaa ttagtgtcca
    11701 ttatgattcc tggaatgata aagcaaataa ggatagagct gaagaactcg ttaatgttcc
    11761 cataattcca ctaaatgatc attcttgtct tgtattggat aaacttggaa acatcataga
    11821 gaaaattgac taactttcat aatgtaaaaa tggatctagg aaataaaagt gtagacgaac
    11881 tggataggtt actagtgaaa actgcaaaaa gtgttgtaaa gtgaatcgga gtgtgcttga
    11941 tggattttag tagtaagata gccataaata agggctggtc agatgataaa aaatattgtg
    12001 tgacagatca aaatcagtaa aaatatttct tgcgtgtttc tgataagtcg aagttagatt
    12061 ataaaaaaat ttgaatttga tatgatggag aaagtagctt ctcttggagt tccgatgtgt
    12121 aaaccaatta gcattgaact ctgcgatgac gaagtacatt ctttacacga atggatagac
    12181 ggaagagatg caatagatag cattttagct tattcagaaa accaacaata cacatatggt
    12241 gtagaagcag gaaagatact tagaaagatt catacaattc ctgctacaga agtttgtgaa
    12301 gattgggaaa tttttttaat ctaaaaattg atgataaaat ctccaacgaa atgatatggt
    12361 aagtccgaaa cgctcagtgt gtaagcttgt tgctaaaagc gtaaaaacct tggaacgaaa
    12421 ggaataatag acttcctgcg aaacaaaaat acaatacaat aaaactatgg atgatgaagc
    12481 aagtaaacaa ttaagcgata gccgtttcaa gatccttgta ggtgttcagc gcacgacttt
    12541 tgaagagatg ttagctgtgt taaaaacagc ttatcaacgt aaacgcgcaa aaggtggacg
    12601 aaaaagcaaa ttaagcctag acgatctcct tatggtaact attcaataca tgcgagaata
    12661 gagcacttat gaacaaattg cggctgattt tggcattcac gaaagcaact taatccgtcg
    12721 gagtcaatgg gttgaagcaa ctcttattca aaatggtttt acgatttcaa attctgcctt
    12781 aattctgtaa aaacagtaaa attcgaagga ttgtaaggta agagtttttt tctttctgaa
    12841 aaaatggtat aatagcaatc aaaactagaa aataaaacgg aatttggaac agatttgtct
    12901 gtatcctagt agagtggtga tactatgaag attagtaaga ggcacttatt aaattattcc
    12961 atcttgattc cctacttgct tttatctatt ttgggcttga ttgtggtcta ttcgaccacc
    13021 agtgctattt taattgaaga aggcaagagc gccttgcagt tggttcgaaa ccaaggaatc
    13081 ttttggattg ttagtttgat actgattgcc ttaatttata aattgagact agattttttg
    13141 agaaatgagc gactaatcat tttagttata ttaatagaaa tgcttttatt gttcttggct
    13201 cgttttattg gtatttcagt aaacggggca tacggttgga tttcggttgc aggagtaact
    13261 attcagccag ctgagtactt aaaaatcatt attatttggt atttagctca ccgattctcc
    13321 aaacagcaag aagaaatagc tacttatgat tttcaagttt tgactcaaaa tcaatggctt
    13381 ccccgtgctt ttaatgattg gcgattcgtt ctcctagttc tgattggaag tttgggaatt
    13441 ttccctgatt taggaaatgc gactatttta gtcttggttt ccttgattat gtatacagtt
    13501 agtggaatcg cttatcgctg gttttcaacc attctggcgc tcgtatctgc cacttctgtc
    13561 tttgtcttga ccactatcag cctaatcggt gttgagacct tttcaaaaat tccagtattt
    13621 ggctatgtag ccaagcgctt tagtgccttt tttaatcctt ttgccgatcg tgctgatgca
    13681 ggtcaccagt tagctaattc ttattttgcc atggtcaatg gtggttggtt tggtctaggt
    13741 cttggaaact cgattgaaaa acgaggttat ttgccagaag ctcatacaga ctttgtcttt
    13801 tctatcgtga ttgaagaatt tggctttgtt ggtgccagtc ttattttagc tctcttgttt
    13861 ttcatgattt tgcggattat cttggtcggt atccgagcgg agaatccttt caatgccatg
    13921 gttgcactcg gtgtcggagg gatgatgttg gttcaggtat ttgtcaatat cggagggatt
    13981 tcgggcttga ttccatctac aggagtgact ttccctttct tatcccaggg tggaaatagt
    14041 cttctagtct tatcagtggc agtagccttt gtcttaaata ttgatgccag tgaaaaacgc
    14101 gctaagttgt accgagaatt ggaaaatcaa ccaatgaacc ttctgttgaa gtaggataaa
    14161 gaaaggatag tttatgtctc ttcaaaaatt agaaaattat agtaataaaa gtgttgtgca
    14221 agaagaagtc ttgattctaa cagaattact ggaagatatt actaaaaata tgcttgcccc
    14281 agagaccttt gaaaaaataa tacagttgaa agaattatca acgcaggaag attatcaagg
    14341 tctaaaccgt ctagtgacta gcttatcaaa tgatgaaatg gtctatattt cacgctattt
    14401 ctctatctta cctcttttga ttaatatttc agaggatgtg gatttagctt atgaaatcaa
    14461 tcatcaaaat aatattgatc aggactattt aggtaaatta tctacaacga ttaaattggt
    14521 agcagaaaag gaaaatgccg ttgagatcct agaacacttg aatgttgtcc ctgttttgac
    14581 agcccatcca acacaagtgc aacgcaaaag tatgttggat ttaacaaatc atattcatag
    14641 tcttttgcgt aaataccgtg atgttaagtt ggggttgatc aataaagata aatggtacaa
    14701 tgatttgcgt cgttacatcg aaattatcat gcagacagac atgattcgtg agaaaaaatt
    14761 aaaagtgact aacgaaatca cgaatgctat ggaatattat aacagctcct ttttgaaagc
    14821 tgtacctcat ttgacgacgg agtataagcg cttagcgcaa gcgcatggtc tgaatttaaa
    14881 acaggctaaa ccaatcacca tgggtatgtg gataggtggt gaccgtgatg gaaatccatt
    14941 tgttacagca aagaccttga agcagtctgc actcactcag tgtgaagtca tcatgaacta
    15001 ctatgataaa aagatttacc aactttatcg tgaattttct ctttcaacta gcattgtcaa
    15061 cgtcagcaag caagtcagag aaatggctcg tcaatccaag gataactcga tttaccgcga
    15121 aaaagagctt taccgtcgtg ccttgtttga tattcaatca aaaattcagg caactaaaac
    15181 ctatctgatt gaggatgaag aagttgggac tcgttatgaa accgccaatg atttctacaa
    15241 ggatttgatt gccattcgag attctctact agaaaataag ggcgagtcct tgatttcagg
    15301 tgattttgtg gaattattgc aggcagtaga gatatttggt ttttacttag catcaattga
    15361 tatgcgacaa gactctagcg tctatgaagc ctgtgtggca gaactcttga aatcagcagg
    15421 aattcattct cgttatagcg agttgagcga agaagaaaag tgtgaccttc tcttgaaaga
    15481 attagaagaa gatccccgaa ttctttctgc gactcacgca gaaaaatcag aattattagc
    15541 aaaagaatta gctattttta agacggctcg tgttttgaaa gataagttgg gagatgatgt
    15601 catccgtcag accatcattt cacatgcaac cagcctttct gatatgctag aattagctat
    15661 tctgttaaaa gaagtaggac tggtggatac ggaaagggcg cgtgttcaga ttgttcccct
    15721 ttttgaaaca attgaagact tggatcattc agaggaaaca atgagaaaat atctttctct
    15781 tagccttgcc aaaaaatgga ttgactcacg aaataactac caagaaatca tgcttggcta
    15841 ctctgacagt aataaagatg gcggttactt gtcatcatgt tggaccctct acaaggctca
    15901 acaacaattg actgctattg gagatgaatt tggcgttaag gttaccttct tccatggtcg
    15961 tggtggtact gtcggtcgtg gtggtgggcc aacctatgaa gccattacat ctcaaccgct
    16021 caagtctatc aaggatcgta tccgcttgac ggagcagggt gaagtaattg ggaataaata
    16081 cggtaacaaa gacgccgctt actataacct tgaaatgcta gtatcggcag ctattaaccg
    16141 tatgattact cagaagaaga gcgataccaa taccccaaat cgttatgaag ccattatgga
    16201 tcaagtagtg gaccgtagtt acgatatcta ccgtgatttg gtctttggta atgagcattt
    16261 ctatgattat ttcttcgagt caagtccaat caaggctatt tcaagtttta atattggttc
    16321 tcgtccagcc gctcgtaaga ctattactga aatcggtggt ttgcgtgcca tcccttgggt
    16381 attctcatgg tcacagagtc gtgttatgtt ccctggatgg tacggggttg gttcaagctt
    16441 caaggaattt atcaataaaa atccagagaa tattgctatc ttacgagata tgtaccaaaa
    16501 ttggcctttc ttccaatcgc ttctttcaaa tgttgatatg gttttgtcaa aatcaaatat
    16561 gaatattgct tttgaatatg ctaaactttg tgaagacgag caagttaagg ccatctatga
    16621 gactatttta aatgaatggc aagttactaa gaacgttatc ttggctattg aaggacatga
    16681 cgaactctta gctgacaatc catatctaaa agctagtctg gattaccgta tgccttactt
    16741 taatattctc aactatattc agttagagtt gattaaacgc caacgtcgtg gagaattgtc
    16801 cagtgatcaa gaacgattga ttcatatcac catcaacgga attgcgacag gattgcgtaa
    16861 ttcaggttga taattttcaa gagtgaatac taaaagtgaa tatcaaaaaa attctaatag
    16921 actattgaca agtaatttaa aaatgatata atttaaccat tcagaaaagt aatcatacaa
    16981 actttttaga gagtctgtgg tagctgaaaa cagataagtg gcgatgatga aaattgggct
    17041 gaatgctatt tagaatttga aattataaaa attcggtaag cacaccttac agtgcatctc
    17101 gttattgcga gactgagcga tagggaaatt ccctataatt gaggtggtac cgcgcatcga
    17161 cgtcctcaca caagtttttt gtgtgaggat ttttttgatg gaggttagta tggaaagaaa
    17221 acgatggcgt cgcttgttta gataagtgaa atatgttaaa ggaaataaaa aggagaaaca
    17281 gaatgaaaaa taaacgttta attggaatta ttgctgcatt agcagtctta gtagcaggaa
    17341 gcttgattta ttcttcaatg aataaatcag aagctcagaa taataaggat gagaagaaaa
    17401 taaccaagat tggtgtgctt caatttgtga gccatccatc ccttgatttg atttataaag
    17461 ggatccaaga tggacttgca gaagaaggat ataaagatga tcaagttaaa attgatttta
    17521 tgaactcaga aggtgaccaa agtaaggttg cgacaatgag taaacaattg gttgcaaatg
    17581 ggaatgacct tgtggttggt atcgcaacac cagcagccca agggttggct agtgcaacaa
    17641 aagacttacc ggttatcatg gccgctatta cagacccaat tggtgctaac ttggttaaag
    17701 atttgaaaaa accaggtggc aacgttacag gggtatctga ccacaatcca gctcaacaac
    17761 aagttgaact catcaaggct ctgacaccga atgtgaaaac aatcggagct ctttactcaa
    17821 gtagcgaaga caattcaaaa acacaggtcg aagaatttaa ggcttatgct gaaaaagcag
    17881 gtctgacagt ggaaacattt gcagttcctt caacaaatga aattgcctca actgtcactg
    17941 ttatgactag caaggtagat gctatttggg ttccaattga taacaccatt gcatcaggat
    18001 ttccaacggt tgtctctagc aatcaaagtt ctaagaaacc aatttatccc agtgcgacag
    18061 ctatggtaga agtaggtggt ttggcatcag ttgtaattga ccaacatgac cttggtgtgg
    18121 caacaggtaa aatgattgtg caagtcttga aaggtgcaaa accagccgat accccagtca
    18181 atgtcttttc aactggtaag tcagtcatca ataaaaaaat agcacaagaa ctaggtatta
    18241 ctattcctga gtctgttctc aaagaagcag gacaagtcat cgaataaata aggtagggag
    18301 gaggagactc ttcccatttt ttaaaaagat gaatatagaa aggattaaat aaaatatgat
    18361 tgtttccatt atttctcaag gatttgtctg ggctattcta ggtctgggaa tctttatgac
    18421 atttaggatt ttaaactttc cagatatgac gacagaaggt tccttccctc ttgggggagc
    18481 tgttgctgtc actttgataa ccaaaggcgt gaacccattt ttagcgacac ttgttgctgt
    18541 aggagcaggt tgtttggctg gaatggcagc aggccttctt tatacaaaag ggaagatccc
    18601 aaccttgctc tcagggattt tggtgatgac ttcttgtcac tcaatcatgc tcttgattat
    18661 gggacgtgcg aatttaggcc tgcttggaac caagcaaatt caggatgttt tgccttttga
    18721 ttcggatttg aatcaactct tgacaggtct catctttgtg agtattgtta ttgctctcat
    18781 gctctttttc ttggacacta aactcggaca agcctatatt gctacagggg ataatcctga
    18841 tatggctaga agtttcggga ttcatactgg acgcatggag ctcatgggct tggtcttatc
    18901 aaatggtgtg attgcccttg caggtgccct cattgctcag caagaaggct atgccgatgt
    18961 gtctcgaggg atcggggtta tcgttgtggg gcttgcaagt ttgattattg gagaagttat
    19021 tttcaagagt ttgagcttgg cagagcgttt ggttactatc gttgtaggtt ctatcgctta
    19081 tcaattttta gtgtgggcag ttatcgcact tggctttaat acaagttacc ttcgtttata
    19141 cagtgccttg attttagcag tctgcctcat gattccaaca tttaagcaaa caatcttgaa
    19201 aggagccaag ttaagcaaat gacagcaatt gtagaattaa aaaatgcaac caaaatcgtt
    19261 aaaaatggct ttgatgaaga aaagattatt ttaaatgatg tttccttaga aatttttgaa
    19321 cgggacttta tcacgatttt gggcggaaat ggtgctggaa aatcaactct ctttaacact
    19381 atagcaggga ccttatcact aactagtgga actatccgta ttttaggtga agatctcact
    19441 aagttttcac ccgagaagcg tgccaagtac ctgtctcgtg tcttccaaga tccaaagatg
    19501 gggacagctc cccgtatgac ggtcgctgaa aatcttttaa tcgccaagtt tcgtggtgaa
    19561 aagcgtggat tgttaccaag acgcttgact agctataagg atgaatttca ggcaaccatt
    19621 gaaaaagtag gaaatggtct tgagaaacac ttgaatacac cgattgagtt cttatcaggt
    19681 ggacaaagac aggctttgag tctcttgatg gcaaccttga agcgacctga attactcctg
    19741 ttagatgagc atactgctgc cctggatcca aagactagtg ttgctttgat ggaattgaca
    19801 gatgaatttg ttaagaaaga tcagctaaca gcccttatga ttactcatca tatggaagat
    19861 gctctcaaat acggcaatcg cttgattgtc atgaaagaag gacggattat ccaagattta
    19921 aaccaagaag aaaaagcaaa aatgaaaatc tctgattatt atcaactctt tgaataaagt
    19981 agggaaaatg agtgaaatgg tttacttttt ttctgaaata aagtatacta tataaagtaa
    20041 actatgataa catggaggta ttgtgtatgg ttgacaaaca agtcattgaa gaaatcaaaa
    20101 acaatgccaa cattgtggaa gtcataggag atgtgatttc tttacaaaag gcaggacgga
    20161 actatctagg gctctgtcct tttcatggtg aaaaaacacc ttctttcaac gttgtagagg
    20221 acaagcagtt ttaccactgt tttggttgtg gtcgctcagg tgatgtcttt aaattcatcg
    20281 aggagtacca aggggttacc tttatggagg ctgtccaaat cttaggtcag cgtgtcggga
    20341 ttgaggttga aaaaccgctt tatagtgaac agaagccagc ctcgcctcac caagctcttt
    20401 atgatatgca cgaagatgcg gctaaatttt accatgctat tctcatgaca acgactatgg
    20461 gcgaagaggc cagaaattac ctttatcagc ggggtttgac agatgaagtg cttaaacatt
    20521 tttggattgg tttagcacct ccagaacgaa actatctcta tcaacgtttg tctgatcagt
    20581 atcgtgaaga agatttactg gattcaggcc tgttttatct ctcggatgcc aatcaatttg
    20641 tagacacctt tcacaatcgc attatgtttc ccctgacaaa tgaccaagga aaggtcattg
    20701 ccttctcagg tcgtatctgg caaaaaacag attcacaaac ttctaagtat aaaaacagcc
    20761 gatcgactgc aatttttaac aaaagttacg aattatatca tatggatagg gcaaaaaaat
    20821 cttctggaaa aactagtgag atttacctga tggaaggatt catggatgtt attgcagcct
    20881 atcaggctgg aatcgaaaat gctgtggcgt cgatgggaac ggccttgagt cgagagcatg
    20941 ttgagcatct gaaaaggtta accaagaaat tggttcttgt ttacgatgga gataaggctg
    21001 ggcaagccgc gatattgaaa gcattggatg aaattggtga tatgcctgtg caaatcgtta
    21061 gcatgcctga taacttggat cctgatgagt atctacaaaa aaatggtcca gaagacttgg
    21121 cctatctatt aacgaaaact cgtattagtc cgattgagtt ctacattcat cagtacaaac
    21181 ctgaaaacag tgaaaatctg caggctcaga ttgagtttat tgaaaaaata gctcccttga
    21241 ttgttcaaga aaagtccatc gctgctcaaa acagctatat tcatatttta gctgacagtc
    21301 tggcgtcctt tgattatgcc cagattgagc agattgttaa tgagagtcgt caggtgcaaa
    21361 ggcagaatcg catggaagga atttccagac cgacgccaat caccatgcct atcaccaagc
    21421 agttatcggc tattatgagg gcagaagccc atctactcta tcggatgatg gaatcccctc
    21481 ttgttttgaa cgattaccgt ttgcgagaag actttgcatt tgctacacct gaatttcagg
    21541 tcttatatga cttgcttggc cagtatggaa atcttcctcc agaagtttta gcagagcaga
    21601 cagaggaagt tgaaagagct tggtaccaag ttttagctca ggatttgcct gctgagatat
    21661 cgccgcagga acttagtgaa gtagagatga ctcgaaacaa ggctctcttg aatcaggaca
    21721 atatgagaat caaaaagaag gtgcaggaag ctagccatgt aggagataca gatacagccc
    21781 tagaagaatt tgaacgttta atttcccaaa agagaagaat ggagtaataa tggcaacaaa
    21841 acaaaaagaa gtaacaacat ttgacgtaca ggtagcagaa tttatccgta atcataagca
    21901 aaaagggaca gcaacagatg atgaaatcaa tgcaagtctg gttattcctt ttaccttgga
    21961 cgctgatggg attgaagatc tcttgcaacg gattcaggat gcaggcattt ctatcacaga
    22021 taacgaagga aatccaagtg cgcgtgttct tagcaatgaa gaagaaccag aactcagcga
    22081 tgaggacttg attgggtcaa cttctgctaa ggtcaatgac cctgtccgta tgtacttgaa
    22141 agaaataggg gtcgttcctc tcttgaccaa tgaagaggag aaagagttgg cactggctgt
    22201 tgaagctggc gatatcgaag ccaaacaacg tcttgcggaa gccaatcttc gtttggttgt
    22261 ttctattgcc aaacgctatg tcggtcgtgg catgcagttc cttgacttga ttcaagaagg
    22321 aaatatgggc ttgatgaagg cggttgacaa gtttgactat tctaaagggt tcaagttttc
    22381 aacttatgca acttggtgga ttcgtcaggc tatcactcgt gctattgcgg atcaagctcg
    22441 taccatccgt atcccagttc acatggttga aactatcaat aaattggttc gtgaacagcg
    22501 gaatctcctt caagaattgg ggcaagatcc gacaccagaa cagattgctg aacgaatgga
    22561 tatgacacct gataaggttc gtgaaatctt gaagattgcc caagaaccag tatctcttga
    22621 aactcctatc ggtgaagagg acgatagcca ccttggagac tttatcgaag atgaagtgat
    22681 tgaaaatcca gtggattata cgactcgtat cgtcttgcgt gagcaattgg atgaaatctt
    22741 agatactctt acagaccgtg aagaaaatgt tctgcgtcta cgttttggac tagatgatgg
    22801 aaaaatgcgc acacttgaag atgtggggaa agtctttaac gtaactcgtg agcgtatccg
    22861 tcagattgaa gcaaaggctt tgagaaaact acgccaacca agccgcagca aaccgcttcg
    22921 tgattttatt gaagactaag agtgaggaaa atatggctta tacagaagag caaattgaaa
    22981 acatcaaaac acggatttta acagccttgg aagaagtcat cgaccctgag ttgggaatcg
    23041 atattgtcaa tcttggtttg atctatgaga ttcgttttga cggtgacaca gggcaaacag
    23101 agattgacat gactttgaca actatgggtt gtcccttagc agaccttttg acagaccaga
    23161 tttatgatgc tatgatagag gttccagaag taacggatac tgaggttaaa ttagtctggt
    23221 atccagcctg gacagttgaa aaaatgagtc gctatgcccg cattgcccta ggcattaagt
    23281 aaacatataa aagcatgtga gagactgttg gaaaagcgag gaaatttccc ctcttttcct
    23341 ctagtctctc ctttcttttg ctgattttat tcaaagaaaa tgatataata gtagttatgg
    23401 agaaaaagaa attacgcatc aatatgttga gttcaagtga gaaagtagca ggacagggag
    23461 tttcaggtgc ttaccgtgaa ttagttcgtc ttcttcaccg tgctgccaag gaccaattga
    23521 ttgttacaga aaatcttcca atcgaggcag atgtgactca ctttcatacg attgattttc
    23581 cctattattt atcaaccttc caaaagaaac gctcagggag aaagattggc tatgtgcatt
    23641 tcttgccagc tacacttgaa ggaagtttga aaattccatt tttcttaaag ggaattgtga
    23701 aacgctatgt attttctttt tacaaccgga tggagcactt ggttgtggtc aatcctatgt
    23761 ttattgagga tttggtagca gctggtattc cacgtgaaaa agtgacctat attcctaact
    23821 ttgtcaacaa ggaaaaatgg catcctctac cacaagaaga ggtagtcaga ctgcgcacag
    23881 atcttggtct tagtgacaat cagtttatcg tagtaggtgc tgggcaagtt cagaaacgta
    23941 aagggattga tgactttatc cgtctggctg aggaattgcc tcagattacc tttatctggg
    24001 ctggtggctt ctcttttggt ggtatgacag atggttatga acactataag aaaattatgg
    24061 aaaatccccc taaaaatttg atttttccag gcattgtatc gccagagcgg atgcgcgaat
    24121 tgtatgctct agcggatctt ttcttgttgc ctagttacaa tgagctcttt cctatgacta
    24181 ttttagaagc tgcgagttgt gaggctccta ttatgttgcg tgatttagat ctctataagg
    24241 tgattttgga gggaaattat cgggcgacag cgggtagaga agagatgaaa gaggctattt
    24301 tggaatatca agcaaatcct gctgtcttaa aagatctcaa agaaaaggct aagaatattt
    24361 ccagagagta ttctgaagag catctgttac aaatctggtt ggacttttat gagaaacaag
    24421 ccgctttagg gagaaagtaa aaagtgaggt aatctatgcg aattggttta tttacagata
    24481 cctattttcc tcaggtttct ggtgttgcga ccagtattcg aaccttgaaa acagaacttg
    24541 aaaagcaggg acatgctgtt tttatcttta cgacgacaga taaggatgtc aatcgctacg
    24601 aagattggca aattatccgc attccaagtg ttcctttctt tgcttttaag gatcgtcgct
    24661 ttgcctaccg aggttttagc aaggcacttg aaattgctaa acagtatcag ctagatatta
    24721 tccatactca gacagaattt tctcttggcc tgttggggat ttggattgcg cgtgaattga
    24781 aaattccagt catccatacc tatcacaccc agtatgaaga ctatgtccat tatattgcta
    24841 aggggatgtt gatccggccg agtatggtca agtatctggt tagaggtttc ctgcatgatg
    24901 tggatggggt tatttgccct agtgagattg tccgtgactt gctatctgat tataaggtca
    24961 aggttgaaaa acggatcatt cctactggga ttgaattagc caagtttgag cgtccggaaa
    25021 tcaagcagga aaatttgaaa gaactgcgta gtaaactagg gattcaagat ggtgaaaaga
    25081 cgttgcttag tctttcgaga atctcctatg aaaaaaatat tcaagcagtt ttagcagcct
    25141 ttgctgatgt tctgaaagag gaagacaagg ttaaactggt agtagctggg gatggccctt
    25201 atctgaatga cctcaaagag caagcccaga acctagagat tcaagactca gtcatcttta
    25261 cagggatgat tgctcctagt gagacggctc tttactataa agcggcggat ttcttcattt
    25321 cggcatcgac aagcgaaacg caaggtttga cctacttgga aagcttagcc agtggaacac
    25381 ctgtcattgc tcacggaaat ccttatttga acaacctcat cagtgataaa atgtttggaa
    25441 ccttgtacta tggagaacat gatttggctg gtgctatttt ggaagccctg attgcaacac
    25501 cagacatgaa cgagcatacc ttatcagaga aattgtatga gatttcagct gagaactttg
    25561 gaaaacgagt gcatgagttt tatctggatg ccattatttc aaataacttc cagaaagatt
    25621 tggctaaaga tgatacggtc agtcagcgta tctttaagac agttttgtat cttcagcaac
    25681 aggtggttgc tgtacctgta aaaggatcta gacgcatgtt gaaggcttca aaaacacagt
    25741 tgatcagtat gagagactat tggaaagacc atgaagaata gaaagaggaa cagctatgaa
    25801 aaaaacaatt aatgagaagc ggtcgtgata aaaagattgc gggtgtttgt gctggggtgg
    25861 cccattatct ggatatggat ccgactatcg ttcaagtcat ttggggtgtt cttacttgct
    25921 gttacggagc tggaattgta gcttacatta ttttatggat tatcgcacca gtagcaactg
    25981 actattgaaa actagctcaa ttcatgctaa gataatagaa aatagaatgt aacgaaggag
    26041 agaaaaatgg catttggaga taatggaaat cgtaaaaaaa ctatgtttga gaaaataacc
    26101 ttgtttatcg tgattatcat gctagtagca agtttattgg gaatttttgc aactgcaatt
    26161 ggtgccctca gtaatctata aaatagattc aagaaaattt agtgactggg atttcccagc
    26221 ccttttttaa agtgagaaga aataatgagt atgtttttag atacagctaa gattaaggtc
    26281 aaggctggta atggtggcga tggtatggtt gcctttcgtc gtgaaaaata tgtccctaat
    26341 ggaggccctt ggggtggtga tggtggtcgt ggaggcaatg tggtcttcgt tgtagacgaa
    26401 ggactacgta ccttgatgga tttccgctac agtcgtcatt tcaaggctga ttctggtgaa
    26461 aaagggatga ccaaagggat gcatggtcgt ggtgctgagg accttagagt tcgagtacca
    26521 caaggtacga ctgttcgtga tgcggagact ggcaaggttt taacagattt gattgaacat
    26581 gggcaagaat ttatcgttgc ccacggtggt cgtggtggac gtggaaatat tcgtttcgcg
    26641 acaccaaaaa atcctgcacc ggaaatctct gaaaatggag aaccaggtca ggaacgtgag
    26701 ttacaattgg aactaaaaat cttggcagat gtcggtttag taggattccc atctgtaggg
    26761 aagtcaacac ttttaagtgt tattacctca gctaagccta aaattggtgc ctaccacttt
    26821 accactattg taccaaattt aggtatggtt cgcacccaat caggtgaatc ctttgcagta
    26881 gccgacttgc caggtttgat tgaaggggct agtcaaggtg ttggtttggg aactcagttc
    26941 ctccgtcaca tcgagcgtac acgtgttatc cttcacatca ttgatatgtc agctagcgag
    27001 ggccgtgatc catatgagga ctacctagct atcaataaag agctggagtc ttacaaactt
    27061 cgcctcatgg agcgtccaca gattattgta gctaataaga tggacatgcc tgagagtcag
    27121 gaaaatcttg aagactttaa gaaaaaattg tctgaaaatt atgatgaatt tgaagagtta
    27181 ccggctatct tcccaatttc tggattgacc aagcaaggtc tggcaacact tttagatgct
    27241 acagctgaat tgttagacaa gacaccagaa tttttgctct acgacgagtc cgatatggaa
    27301 gaagaagctt actatggatt tgacgaagaa gaaaaagcct ttgaaattag tcgtgatgac
    27361 gatgcgacat gggtactttc tggtgaaaaa ctcatgaaac tctttaatat gaccaacttt
    27421 gatcgtgatg aatctgtcat gaaatttgcc cgtcagcttc gtggtatggg ggttgatgaa
    27481 gcccttcgtg cgcgtggagc taaagatggg gatttggtcc gcattggtaa atttgagttt
    27541 gaatttgtag actaggagac tggtatggga gataaaccga tatctttccg agatgcggat
    27601 ggtaattttg tttccgccgc agacgtttgg aatgaaaaga aattggaaga actatttaat
    27661 cgtctcaatc caaatcgtgc cttgagattg gcacgaacta aaaaggaaaa tccatctcag
    27721 taaagaagct aaaaaatccc gtgcctcatc agacacggga ttttgtggta cgacgggcat
    27781 gtatagcgaa ctgaatctgg aatagcacag catatcttct aaaatatagt aaaatgaaat
    27841 gagaacagga caaatcgatt tctaacaatg ttttagaagt agaggtgtac tattctagtt
    27901 tcaatcaact atattgttat aaattgattt gaatttcaaa attaaattgt ttgattctta
    27961 tttcaatttg ttatagtata tctgatgtca aagttctcgg cgagtcaaat agcgattccc
    28021 aagcctgact atcgtgaggt agcggattaa aatggtctgg ggatagaccg ttttaagtct
    28081 gacgctggaa ataagaattg tcagaagaag ggatagagaa atcgtggctc tacgaacagg
    28141 aacgtgataa taaggcgtat atagcggata agagggcctc aaactctaaa gtccaaaaag
    28201 gtagtcgtaa cctaataaag agaaaacgac agatagaagt gatcctgagt cacggttatc
    28261 tttaaaatag attgtctgat aggacggtat gtataaaacg cttctgtgaa ctgagagaag
    28321 gggagaagtt cttgctaaaa tttagttgaa cagccgtatt ccgatactta gataagagat
    28381 ctagtcttag cccctactca gttttagggg ataaaaaagg ggcaatagcg attcgagaaa
    28441 gattatactc ttcgaaaatc tcttcaaatc acgtcaatat cgccttgccg tatgtgtagg
    28501 atactgacta cgtcagttcc atctacaacc tcaaaacagt gttttgagca acctgcggtt
    28561 agtttcctag tttgatcttt gattttcatt gagtattagt aattcagtta ctaactcgtc
    28621 aactctgatt tatccaataa aattgaaaag gatggaaaaa aggataaatt tatgatatac
    28681 tttattttga agaccttatt agaaatcttg aaagagtatt gaaaacttag aatgagaaaa
    28741 attgttatca atggtggatt accactgcaa ggtgaaatca ctattagtgg tgctaaaaat
    28801 agtgtcgttg ccttaattcc agctattatc ttggctgatg atgtggtgac tttggattgc
    28861 gttccagata tttcggatgt agccagtctt gtcgaaatca tggaattgat gggagctact
    28921 gttaagcgtt atgacgatgt attggagatt gacccaagag gtgttcaaaa tattccaatg
    28981 ccttatggta aaattaacag tcttcgtgca tcttactatt tttatgggag cctcttaggc
    29041 cgttttggtg aagcgacagt tggtctaccg ggaggatgtg atcttggtcc tcgtccgatt
    29101 gacttacacc ttaaggcgtt tgaagctatg ggtgccactg ctagctacga gggagataac
    29161 atgaagttat ctgctaaaga tacaggactt catggtgcaa gtatttacat ggatacggtt
    29221 agtgtgggag caacgattaa tacgatgatt gctgcggtta aagcaaatgg tcgtactatt
    29281 attgaaaatg cagcccgtga acctgagatt attgatgtag ctactctctt gaataatatg
    29341 ggtgcccata tccgtggggc aggaactaat atcatcatta ttgatggtgt tgaaagatta
    29401 catgggacac gtcatcaggt gattccagac cgcattgaag ctggaacata tatatcttta
    29461 gctgctgcag ttggtaaagg aattcgtata aataatgttc tttacgaaca cctggaaggg
    29521 tttattgcta agttggaaga aatgggagtg agaatgactg tatctgaaga cagcattttt
    29581 gtcgaggaac agtctaattt gaaagcaatc aatattaaga cagctcctta cccaggcttt
    29641 gcaactgatt tgcaacaacc gcttacccct cttttactaa gagcgaatgg tcgtggtaca
    29701 attgtcgata cgatttacga aaaacgtgta aatcatgttt ttgaactagc aaagatggat
    29761 gcggatattt cgacaacaaa tggtcatatt ttgtacacgg gtggacgtga tttacgtggg
    29821 gccagtgtta aagcgaccga cttaagagct ggggctgcac tagtcattgc tgggcttatg
    29881 gctgaaggta aaactgaaat taccaatatc gagtttatct tacgtggtta ttctgatatt
    29941 atcgaaaaat tacgtaattt aggagcggat attagacttg ttgaggatta aaccgtagag
    30001 gtgtttatga atatttggac caaattagca atgttttctt tttttgaaac ggatcgcttg
    30061 tatttgcgtc ctttcttttt tagtgatagt caggacttcc gcgagatagc ttcaaatcca
    30121 gaaaatcttc aatttatttt cccaacgcag gcaagtctgg aagaaagtca atatgcactg
    30181 gccaattact ttatgaagtc ccctttggga gtgtgggcaa tttgtgacca gaaaaatcaa
    30241 caaatgattg gttctattaa atttgagaag ttagatgaaa tcaaaaaaga agctgagctt
    30301 ggctattttt tgagaaaaga tgcttggtcg caaggattta tgacagaggt tgttagaaaa
    30361 atttgtcagc tttcttttga ggaatttggc ttaaaacaat tatctatcat tacccacctt
    30421 gaaaatgaag ctagccaaag agttgctctt aagtctggat ttagtttgtt ccgtcagttt
    30481 aagggaagtg atcgttacac aagaaaaatg cgggattatc ttgaatttcg gtatgtaaaa
    30541 ggagagttca atgagtaagc atcaggaaat tctaagctat ttggaggaat taccagtagg
    30601 taaaagggtc agtgttcgta gcatttcgaa tcatctagga gttagtgatg gaacagccta
    30661 tcgggctatt aaagaagctg aaaaccgtgg aattgtggag acccgtccta gaagtggaac
    30721 aattcgtgtt aaatcccaga aagttgctat agagagatta acgtttgctg aaattgcaga
    30781 agtgacttct tctgaggttc tggctgggca agaaggttta gagagagaat ttagtaagtt
    30841 ttcaattggt gccatgactg aacaaaatat cttgtcttac cttcatgatg gggggctctt
    30901 gattgtcgga gaccgaaccc gtattcagtt gctagccttg gaaaatgaaa atgcagttct
    30961 ggttacaggg ggatttcagg ttcatgatga tgtgcttaaa ctggccaatc aaaaagggat
    31021 tcctgttcta agaagtaagc atgatacctt taccgtcgcg accatgatca ataaagcctt
    31081 gtcaaatgtc caaatcaaga ctgatattct gacagttgag aaactttatc gccctagtca
    31141 tgagtatggt tttctgagag agacagatac agttaaagat tatttggact tggttcgtaa
    31201 gaatcgtagc agccgtttcc ctgttatcaa tcaacatcag gtcgttgttg gcgttgtaac
    31261 catgagagac gctggtgata aatcaccaag cacgacaatt gataagatta tgtctcgtag
    31321 tctatttttg gttggattat cgacaaatat tgccaatgtg agtcaacgga tgatcgcaga
    31381 agactttgaa atggtaccag ttgttcgaag caatcaaact ttgcttggcg ttgtgacgcg
    31441 acgagatgtc atggagaaga tgagccgttc tcaagtttcg gctctaccaa ctttttctga
    31501 gcagattgga caaaagctct cttatcacca tgatgaagta gtcattacag tggaaccctt
    31561 tatgctagaa aaaaatggag ttttggctaa tggtgtattg gcagaaattc tgacccacat
    31621 gacccaagat ttagttgtta atagtggtcg caatctcatt atcgagcaga tgctaatcta
    31681 ctttttgcag gctgttcaga tagatgatat attgcgcatt caggcacgga ttattcatca
    31741 tacgagacgg tcagctataa ttgattacga tatttatcat ggtcaccaga ttgtttcaaa
    31801 agcaaatgtg actgttaaaa ttaattagaa actaggagaa aagatgataa cattaaaatc
    31861 agctcgtgaa atcgaagcta tggacaaggc tggtgatttt ctagcaagta ttcatatagg
    31921 cttacgtgat ttgattaagc caggcgtaga tatgtgggaa gttgaagaat atgtccgccg
    31981 tcgttgtaaa gaagaaaatt tccttccact tcagattggg gttgacggtg ccatgatgga
    32041 ctatccttat gctacctgtt gctctcttaa cgatgaagtg gctcacgctt tccctcgtca
    32101 ttatatcttg aaagatggtg atttgctcaa agttgatatg gttttgggag gtcccattgc
    32161 taaatctgac ctgaatgtct caaaattaaa cttcaacaat gttgaacaaa tgaaaaaata
    32221 cactcagagc tattctggtg gtttagcaga ctcatgttgg gcttatgctg ttggtacacc
    32281 gtccgaagaa gtcaaaaact tgatggatgt aaccaaagaa gctatgtaca agggtattga
    32341 gcaagctgtt gttggaaatc gtatcggtga tatcggtgcg gctattcaag aatacgctga
    32401 aagtcgtggt tacggtgtag tgcgtgattt ggttggtcat ggtgttggcc caactatgca
    32461 cgaagaacca atggttccta actatggtat tgcaggtcgt ggactccgtc ttcgtgaagg
    32521 aatggtctta accattgaac caatgatcaa tacaggcgat tgggaaattg atacagatat
    32581 gaaaactggt tgggcgcata agaccattga cggtggattg tcatgtcagt atgaacacca
    32641 atttgtcatt acgaaagatg gacctgttat cttgactagc caaggtgaag aaggaactta
    32701 ttaataaaaa gtgaaaagac tactggaagt ttattatgaa aaaatccagt agatcttttc
    32761 ataataaaac gcattgtatc aagtgttagg ggctgatatc atgcgttttt ctgcttttaa
    32821 gattttttcc aactctgttt gtaagcgcat cataacaaag ggtctaggat tcagggctct
    32881 cctcctatat actattagta aagtaaaact aagggaggat attttagtgt cgcagtctat
    32941 tgttcctgta gagattccac aatattgtcg ttttgattct aaaaagagaa atggaattct
    33001 gtttaatgtt cgtattgcca atcttaaatt tacctttttt agattagact tcctgcgaaa
    33061 caaaatatgg tatagtagtt ctatgaatga tgaagcaagt aaacaactaa ctgatgcacg
    33121 atttaagcgt cttgttggtg ttcagcgcac gacttttgaa gagatgttag ctgtattaaa
    33181 acagcttatc aacttaaaca cgcaaaaggt ggacgaaaac ctaaattaag cctagaagac
    33241 cttcttatgg ccactcttca atatgtgcga gaatatcgaa cttatgaaca aattgcggct
    33301 gatcttggta ttcacgaaag caacttaatc cgtcggagcc aatgggttga agtaactctt
    33361 gttcaaaggt ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat
    33421 tgatgcgacg gaagtaaaaa tcaatcgtcc taaaaaaatc aactagccaa t
//
LOCUS       DAVDHC010000021        33384 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVDHC010000021 DAVDHC010000000
VERSION     DAVDHC010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33384
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.021"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(147..914)
                     /locus_tag="VUR43_001403"
     CDS             complement(147..914)
                     /locus_tag="VUR43_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET5413077.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(911..1777)
                     /locus_tag="VUR43_001404"
     CDS             complement(911..1777)
                     /locus_tag="VUR43_001404"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET5413078.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(1814..3181)
                     /gene="accC"
                     /locus_tag="VUR43_001405"
     CDS             complement(1814..3181)
                     /gene="accC"
                     /locus_tag="VUR43_001405"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET5413079.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(3193..3615)
                     /gene="fabZ"
                     /locus_tag="VUR43_001406"
     CDS             complement(3193..3615)
                     /gene="fabZ"
                     /locus_tag="VUR43_001406"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET5413080.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     LMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(3612..4097)
                     /locus_tag="VUR43_001407"
     CDS             complement(3612..4097)
                     /locus_tag="VUR43_001407"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET5413081.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(4100..5335)
                     /gene="fabF"
                     /locus_tag="VUR43_001408"
     CDS             complement(4100..5335)
                     /gene="fabF"
                     /locus_tag="VUR43_001408"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET5413082.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(5357..6088)
                     /gene="fabG"
                     /locus_tag="VUR43_001409"
     CDS             complement(5357..6088)
                     /gene="fabG"
                     /locus_tag="VUR43_001409"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET5413083.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(6122..7042)
                     /gene="fabD"
                     /locus_tag="VUR43_001410"
     CDS             complement(6122..7042)
                     /gene="fabD"
                     /locus_tag="VUR43_001410"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET5413084.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(7035..8009)
                     /gene="fabK"
                     /locus_tag="VUR43_001411"
     CDS             complement(7035..8009)
                     /gene="fabK"
                     /locus_tag="VUR43_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET5413085.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(8129..8353)
                     /locus_tag="VUR43_001412"
     CDS             complement(8129..8353)
                     /locus_tag="VUR43_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET5413086.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(8413..9387)
                     /locus_tag="VUR43_001413"
     CDS             complement(8413..9387)
                     /locus_tag="VUR43_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET5413087.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(9387..9821)
                     /locus_tag="VUR43_001414"
     CDS             complement(9387..9821)
                     /locus_tag="VUR43_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5413088.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(9915..10700)
                     /locus_tag="VUR43_001415"
     CDS             complement(9915..10700)
                     /locus_tag="VUR43_001415"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET5413089.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            11025..12389
                     /locus_tag="VUR43_001416"
     CDS             11025..12389
                     /locus_tag="VUR43_001416"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET5413090.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            12392..12763
                     /locus_tag="VUR43_001417"
     CDS             12392..12763
                     /locus_tag="VUR43_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET5413091.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            12977..14251
                     /gene="serS"
                     /locus_tag="VUR43_001418"
     CDS             12977..14251
                     /gene="serS"
                     /locus_tag="VUR43_001418"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET5413092.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKKIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(14276..15175)
                     /locus_tag="VUR43_001419"
     CDS             complement(14276..15175)
                     /locus_tag="VUR43_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET5413093.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(15285..15833)
                     /locus_tag="VUR43_001420"
     CDS             complement(15285..15833)
                     /locus_tag="VUR43_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET5413094.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(16051..17373)
                     /locus_tag="VUR43_001421"
     CDS             complement(16051..17373)
                     /locus_tag="VUR43_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET5413095.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVMSPVVIAETKKYFDK"
     regulatory      complement(17464..17552)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(17716..20052)
                     /locus_tag="VUR43_001422"
     CDS             complement(17716..20052)
                     /locus_tag="VUR43_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET5413096.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELAFWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVVSRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKAV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(20156..20704)
                     /locus_tag="VUR43_001423"
     CDS             complement(20156..20704)
                     /locus_tag="VUR43_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET5413097.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEDQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(20701..21003)
                     /gene="zapA"
                     /locus_tag="VUR43_001424"
     CDS             complement(20701..21003)
                     /gene="zapA"
                     /locus_tag="VUR43_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET5413098.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            21090..21962
                     /locus_tag="VUR43_001425"
     CDS             21090..21962
                     /locus_tag="VUR43_001425"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET5413099.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            21974..22588
                     /gene="lepB"
                     /locus_tag="VUR43_001426"
     CDS             21974..22588
                     /gene="lepB"
                     /locus_tag="VUR43_001426"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET5413100.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            22822..25188
                     /locus_tag="VUR43_001427"
     CDS             22822..25188
                     /locus_tag="VUR43_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET5413101.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGEQKRQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDAEFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(25236..26519)
                     /locus_tag="VUR43_001428"
     CDS             complement(25236..26519)
                     /locus_tag="VUR43_001428"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET5413102.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDQKFGEEALYQDAMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEETYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(27318..28454)
                     /locus_tag="VUR43_001429"
     CDS             complement(27318..28454)
                     /locus_tag="VUR43_001429"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HET5413103.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVDPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIADEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(28516..28953)
                     /locus_tag="VUR43_001430"
     CDS             complement(28516..28953)
                     /locus_tag="VUR43_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5413104.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYESGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKNDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLAGAQSKEEVLRLFDAVE"
     gene            complement(28955..30910)
                     /locus_tag="VUR43_001431"
     CDS             complement(28955..30910)
                     /locus_tag="VUR43_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET5413105.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(30934..32703)
                     /locus_tag="VUR43_001432"
     CDS             complement(30934..32703)
                     /locus_tag="VUR43_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HET5413106.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPMANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFLVA
                     ALILHADKSTEDSLEAAQAATQAAKAQSKGQLVSTSVDAVVSTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
     gene            32912..33384
                     /locus_tag="VUR43_001433"
                     /pseudo
     CDS             32912..33384
                     /locus_tag="VUR43_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9878 a         7490 c         6345 g         9671 t
ORIGIN      
        1 cttaaaatag attgttgtag gctcacattt atagtatatt tctttttttg tctattttat
       61 agtctatctc ctcaactgtc aatttttcaa cctgaattgc atttttccat aaaaaatgag
      121 acctttctag tctcatttag tcattcttag tattttctaa atcgttgata gcgttcttcc
      181 agcaactctt ctagcggttt ttgtgaaagt ctagccagct ccgtttggag ttcttttttg
      241 acactcttaa tcagttcttt actagaaagt cctatttcag aaatcacctt atccaccacg
      301 tccatttcta acagttcatg cgaagtgatt ttcatcagtt ctgctgcttc catggcgcga
      361 gtaccgtcct tccataaaat ggaagcaaag ccttctggac tgagaatggc atagatagaa
      421 ttttccagca tccagacacg gtccgcgaca gctagagcca gagccccgcc tgaaccacct
      481 tcaccgataa taatggcgat aataggaact ttcaggtcac tcatttccat gagattgcga
      541 gcgatagctt ccccttgacc acgttcttcc gctccgacac caggataagc acctgctgta
      601 ttgataaagg tcacaactgg acggccaaat ttctcagcct gtttcatcaa ccgcagtgcc
      661 tttcggtagc cttctggatg tggttggcca aaattccgtt tgaggttgtc ttgcaaactc
      721 ttgccttttt ggataccaac cactgttaca gcttggtctc caagccaacc aataccacca
      781 acaactgcac catcatcacg aaaagaacgg tcaccatgta attggataaa ttcatcaaaa
      841 atgcctgtcg caaagtccaa ggttgtcaag cgactctgct cacgcgcttc tctgactatt
      901 tttgcaatat tcatctagga ctccctccat gcaatctgac taggctagca atcgtatctg
      961 gtaagtctct tcttttgaca atagcatcca caaagccatg ttctaatagg aattctgcct
     1021 tttggaaatc ctcaggcaag ctttcacgaa ccgtattttc aatcacacga cgcccagcaa
     1081 aaccaaccaa gctctgtggt tcagccagaa tgatatcgcc ttccatagcg aaagaagctg
     1141 tcacaccacc agtcgttgga tctgtcaaaa tggtcaggta aaagagacca gcatttgaat
     1201 ggcgtttaac cgccgcagag atcttagcca tctgcatgag actcatgatt ccttcctgca
     1261 tacgggctcc accagaggct gtgaatagga caactggcaa tttttcgaca gtcgcatact
     1321 caaacaaacg agtgattttt tcacctacaa ccgtacccat agaagccatg ataaagttag
     1381 aatccataat cccaagagcc acagtctgac ctttaataag agcagttcct gtcacaacgg
     1441 cttcatgcag acctgttttt tcacgcatag atgccagttt cttttggtaa ccagggaaat
     1501 gcaagggatc cttgctttca atccctgtaa acaattcttt gaaggttccc atatcaatcg
     1561 tcaaagccaa gcgttcttgg gcagaaatac gaaaggtata gctacagtgc ggacagatac
     1621 gttcacttcc cagatccttc tgatagatgg tatgcttaca gcctggacac tgggaaaata
     1681 attcatctgg aacctctggc ttagcttgag gtttttccct aaccgaacga ttgggattga
     1741 ttcgaatata cttatctttt ttactaaata gagccattga ttcccctttt cggtttaaac
     1801 tcttaaagtc attttattct ttttcttgat atttaggtaa gaaggtttcc atcaagaagg
     1861 aagtatcata atccccagca atgacattgc gatctgaaat gaggtcaagc tggaaatctg
     1921 cattggtctg cactccttca atctctaatt catagagggc acgttgcatt ttcatcaagg
     1981 cgtcaaaacg attttcgccg tgtactatga ttttggcaat catactatca taataaggcg
     2041 gaatggtata acctggataa actgctgaat ccacgcgcaa gccaactcca ccacttggca
     2101 gatagagatt agtaatctta cctggacttg gagcaaagtt aaaggctggg ttttctgcat
     2161 tgatacgaca ctcgatggca tgaccgcgta ggacaatatc ttcttgctta acagacaaag
     2221 gctgacctgc cgcaatgcaa atctgttcct taacgatatc aacacctgaa acaaactctg
     2281 ttactggatg ttctacctga acacgagtat tcatctccat gaaatagaaa ttgctacttg
     2341 cttcatcaag aagaaattca atggttcctg cattctcata gccaacaaac tctgccgctc
     2401 gaacagcagc agcacctatt tcatgacgca gcgtttttcc gattgcaatc gagggacttt
     2461 cttccaaaac cttttggtta ttcctttgaa gagaacaatc ccgctcaccc aagtgaatca
     2521 catgtccatg ctcatcacct aggatttgaa cctcaatgtg ccgagctgga tagataaccc
     2581 gttctatgta catggcacca ttgccataat tggccttggc ctcactagag gcagtttcaa
     2641 aggcagaaac gaggtcatct ggtttttcaa ccttacgaat ccctttacca cctccacctg
     2701 ctgaagcctt gagcataaca ggatagccaa ttttttcagc aacaatcaaa gcttcttcag
     2761 agttatgcac ttctccatct gaacctggta taacaggcac acctgcttta atcatctgag
     2821 cacgcgcatt gatcttatcc cccatcatat ccataacatg accagatgga ccgataaact
     2881 tgatacctac ttcttcacac atggtcgcaa atttggaatt ttcactgaga aatccaaaac
     2941 cagggtgaat agcttctgcc tcagtcaaga ctgcagctga tagaactgca ttaatattga
     3001 gataagactc tgttgccttg ccaggaccaa tacaaactgc ttcatctgcc aaaagcgtat
     3061 gaagagcttc cttatcagca gttgaataaa ccgctaccgt cgcaatcccc aattcacgtg
     3121 ccgcacggat aatacgaacc gcaatttcac cacgattggc aattaaaatt tttcgaaaca
     3181 tggagaacct ccttagttcc caattgcaaa agtaaggata ccactggctg caagcttgcc
     3241 atccacttca gcctttgctt caaccacagc tatggtgcca cgacgtttta caaaagtcgc
     3301 tgtcataagc aattggtcgc ctggtacaac ttgcttcttg aacttaacct tgtccatacc
     3361 agcgtaaaag accagttttc ctttattttc aggttttgat aactctaaca caccagcagt
     3421 ttgcgccaag gcttccataa tcagaacacc tggcataact gggtattgag gaaagtggcc
     3481 gttaaagaaa ggttcgttaa tggtcacatt tttgatagca acaatggtat cctcgctcac
     3541 ttccaagaca cggtccacta gaagcatagg ataacggtgg ggaagagctt ctttgattcc
     3601 ttgaatatcg atcatttgat acgtaccaat cctttaccaa actcaaccat ttcttcgtta
     3661 gagacgagaa tttccgttac cacaccatcc ttaggagctg ggatttcatt catgactttc
     3721 atggcttcga taattaccaa tgtttgacct tttttgacac tatcaccaac tgtaacgaag
     3781 gcaggtttat ctggtccagc agccaagtaa accactccaa caagtggact ctctacaaga
     3841 tttccctcag tagccacact tgcttcagct ggagctggaa cttcttctgc tacagtctct
     3901 gctggagcag atgtaggagc tactggactc ggtgttgcta gaacgggtgc tggagcgact
     3961 tgagttgcaa cttcaggcac aggtctcgct tcattcttgc taaactgcaa ctcatccgtc
     4021 ccatttttat aagaaaattc tctcaaactt gactggtcaa attgagtcat caagtcttta
     4081 atatcgttta aattcatact tatctattct cccaacgttt gaaagcaaga actgcattgt
     4141 ggcctccaaa accaaaagta tttgaaatag cgtatggaat ttctttctcc aagccttgtc
     4201 cataaacgac attagcttcg atataatctg atacttcact tgtcccagct gtcattggta
     4261 caaagttatg gcgcatagct tcgatggtga cgatagcttc tactgcaccc gcagccccca
     4321 gcaaatgtcc tgtaaaagac ttggttgatg atacaggtac ttccttacca agaacagcta
     4381 cgatagctcc actttctcct ttttcattgg caggagttga cgttccgtga gcattgacat
     4441 aggctacttg ctctggagaa atctcagctt cttccaaggc tagtttgatg gccttgatag
     4501 ctccctgacc ttctggatgt ggagaagtca tgtggtaggc atcacaagta tttccgtaac
     4561 caaccacttc agccaggata gtagctccac gtttttcagc gtgttcaaga ctttctaaaa
     4621 ccaacatccc tgaaccttca cccataacaa acccattgcg atccttatca aatgggatcg
     4681 aagcacgagt tggatcctct gtagtagaga gagctgttaa ggcttggaaa ccagcgatgg
     4741 caaaaggtgt gatagaagct tctgttcctc ccaccaacat cacatcttgg aaaccaaact
     4801 taatggagcg gaaggcatcc ccaatcgcat catttgatga agagcaggca gtattgatag
     4861 atttacaaac accgtttgca ccaaaacgca tggctacatt cccagaagcc atatttggta
     4921 aagcttttgg aagagtcatt ggtttgacac gtttgggtcc tttttcatga aggcgaagta
     4981 cctgatcttc aatttccttg attccaccaa taccagatgc aacgataaca ccaaaacgat
     5041 ccctattaag agcctctaca tcaagattgg catgatttac agcctcttgg gctgcataca
     5101 aggcatataa agaatagtta tcaaaacggt tggtatcttt ttttacaaag tatttatcga
     5161 acggaaaatc ttggatttct gccgcattat gcacatcaaa gtcactatga tcaaattttg
     5221 taatgccacc aatgccgatt ttcccagttg ctaaactatt ccaaaattct tctggtgtat
     5281 ttccgattgg agatgttact ccataacctg ttaccactac tcgatttagt ttcattcttt
     5341 tcacctctag ctttcgctac atacttaagc caccatcaat ggcaaccact tgaccagtta
     5401 gataatcttg gcctgctaaa aatactgtca aatctgcaac ctgctctgcc tgcccaaatt
     5461 ctttcatcgg aatctgagct agtgtagctt ccttaatctt atctgataag atagctgtca
     5521 tatcagactc aatcattcct ggagcaatca cattgactcg tatattccga ctagcgacct
     5581 cgcgtgccac agacttggta aagccaatca agccagcctt agaagcagca tagttagctt
     5641 gaccaatatt ccccatcaaa ccaacaacac tagacatatt aatgatagca ccttctctgg
     5701 ctttcatcat cggtttcaag actgattgtg tcatattaaa ggcaccagtc agattgacct
     5761 tgagcacttt ttcaaaatct gcttctgtca tcttgagcat aagagtatct tgggtaatcc
     5821 ctgcattgtt gaccaaaaca tctactgaac ccagttctgc aatagcttga tcaatcatac
     5881 gcttagcgtc tgcaaaatct gatacatctc ctgaaatggg aaccaccttg ataccatagt
     5941 ttgaaaactc agcgagcaat tcttctgaga ttgccccacg actgtttaag acaatgttgg
     6001 ctcctgcttg agcaaacttg tgggcgatgg caagaccaat tccacgactc gaacctgtaa
     6061 taaagatatt tttatgttct agtttcattt ttttcctttc aaaacttcta cttattttag
     6121 tctatttttc taaaagtgct actaaactcg cttgatcttc cacatgagct aagtgagcag
     6181 tttgatcaat ttttttaaca aaacctgaca agactttccc cggtccaatc tcgataaagt
     6241 tgcttatgcc tgcttcttgc atgaccccaa tactttcata gaaacgaacg ggttccttga
     6301 cctgacgcgt caagagctga gcaatgtcct ctttttgcat cacagcagct tctgtattgc
     6361 cgactagggg acaagtaaaa tctgaaaaac ttacctgagc tagagtttca gctagtttct
     6421 ggctagcagg ttcaaggaga gcggtgtgaa agggacctga caccttaaga ggaatcaagc
     6481 gtttggcacc tgcttcttgc aaaagttcaa ccgctcgatc aactgcaacc acttctccag
     6541 caatgacgat ttgtgcaggt gtgttatagt tggctggagt aaccactcca agttcagaag
     6601 ctttttgaca ggcttcttca atgacctcta ctggcgtatt gagaactgct accatcttgc
     6661 cagagtcagc aggagccgct tcttccatat aggctccacg cttagctacc aaggcaaccg
     6721 catcttcaaa atccaaggcg ccgcttgcca ccaaggcaga gtattctcca agagacaaac
     6781 cagcaaccat atcaggctga tagccctttt cttgcaataa acggtagata gcaaccgaag
     6841 tcgctagaat ggctggttgc gtatagcggg tctgattgag tttgtcttct tccgtatcga
     6901 tgagataacg caaatcataa ccgagcacct gactcgctcg atcaatcgtt tctttgacaa
     6961 tcggatactg atcatagaaa tcccgtccca tccctagata ctgggcacct tgaccagcaa
     7021 ataaaaaggc tgttttagtc atttcttaca actcctgtcc agcgagaggc ttcttcttga
     7081 attttcttag cggctccgta atacaaatct tttaggattt cttcagctgt ttcttcttta
     7141 gaaacaagcc ctgcgatttg acctgccata acagagccac catccacatc accgtgaaca
     7201 actgctttgg ctagagcacc tgctcccatt tgttcaaaga tttctaaatc aggatcttct
     7261 tgcttaaagg catctttttc agccagttca aaatctctag tcaactgatt tttaatagca
     7321 cgaacagcat gaccaaagtg ctgagctgaa atcgtagtat caatatccct tgcttttaaa
     7381 attttctcct tgtagtttgg atgggcattc gactcttttg caactacaaa ccgtgtcccc
     7441 acctgtacag cctctgcacc tagcataaag ccagccgcag caccttcacc atccgcaatt
     7501 cctcctgcag caataacagg aatagataca gctgtggcta cctgtcgcac caaagtcatg
     7561 gttgttaatt taccgatatg ccccccagct tccattcctt ctgcaataac agcgtctgca
     7621 ccgatttttt ccatgcgttt agctaaagca acactaggaa caacaggaat aacgattatc
     7681 ccagcttcat ggaaacgttc catatacttg cttggatttc ctgctcctgt tgtgacaact
     7741 ttaacacctt cttcaataac gagatccacg atatcttcca caaagggaga taagagcatg
     7801 atgttgaccc caaagggttt atcagtcaat gatttgattt tatcaatatt ggccttgaca
     7861 acttctttcg gggcatttcc cccaccgata attcctaatc ctccagcctt ggaaacagcc
     7921 cctgccaaat caccatcagc aacccaggcc atccctcctt ggaaaatagg atagtcaatc
     7981 ttcaataatt ctgtaatacg cgttttcata gtgcctccaa ccttccttgc ttacgtaata
     8041 gttcgatttc accataattt gacagtcaaa ctattaccta aacaagaggg agtgggtttc
     8101 tccctactcc ttctacttaa tattctgctt attttgcttg ctcttcaacg taagcaacca
     8161 agtcaccaac tgttttcaag tcattttctg cttcgatttg gatatcaaaa gcatcttcga
     8221 tttctgagat tacttggaac aagtccaatg aatctgcgtc caaatcatca aaagttgatt
     8281 caagtgttac ttctgatgcg tcttttccaa gttcttcaac gataatttct tgtacttttt
     8341 caaatactgc catgatagga ctcctttaaa ataaatagtt tttttataac aatgtgttca
     8401 ccacatgatt acctaaattg taagaatgag cgtgccccag gtcaaacctc caccgaagcc
     8461 tgatagaaga acagtctggc taccatctaa agggatgaga ccttgttcta cacactctga
     8521 aagtaaaatc gggatactgg ctgcactggt attgccatat tccatcatat tggctggaag
     8581 tttggctcgg tcaacaccaa tttttctagc catcttatcc aaaatacggt cattggcttg
     8641 atgaagtagc agataatcca agtctgtcac ctctatagga gattcatcaa tagtctgctt
     8701 gatagacttg gctacatctc gaatggcaaa atcaaagact gtgcgtccat ccatcttcaa
     8761 aaatgaatct gcactttctt gatctgaaaa tggagaatgc aaacctgaat gcccataagt
     8821 taaacactcg ctgcgacttc catcgctatt gagactctca gctaagaaat gctcttgctc
     8881 gctagcttct aacaagacac caccagcacc atctccaaac aacacagctg ttgatcgatc
     8941 cgaccaatcg actgccttag agagggtttc actaccaatc accaagcctt tttgaaagcg
     9001 accagaagcg ataaactttt cagcagttga aagagcaaat acaaatccac tgcaagccgc
     9061 ggttaagtca aaagcaaagg ctttattagc accaatatta gcttgaacac gagcagctgt
     9121 agagggcatc atcgaatctg gagtaatggt agctaggatg ataaaatcca gttcttttcc
     9181 tgttattcca gcttttgcca tcagtttctt agcaacctct gtagccaaat cactggtaga
     9241 ttctgttctt gaaatatgcc tttgtcgtat tcccgttcga cttgaaatcc actcatcatt
     9301 ggtatccata atctgagcca agtcgtgatt tgtaaccact tgctctggca cataatgagc
     9361 aacctgactt atttttgcaa aagccattat ttcaaatcct ccaaaaattg gtaaagatta
     9421 gtcaagcctt tacccatgac agcaatttct tcctcgctca tgccatcaat aattttttct
     9481 accatggcct tgtggaagcg tttatgcagt ctatgaatca agcgaccctt ctttgtcaaa
     9541 tgcagatgca ccacacgacg atcctgttct gaccgaactc gctcaatgta gcccttacgc
     9601 tctaaattgt tcaaacttgt cgtaacagtt ccaagagtta ccatcaactc ttttgacact
     9661 tgacttggag tcacatctgg agccttaccg atgacatcaa tcgtatgcat ttctttgatg
     9721 gagatatcct taaaacgact acctctcaag ttcacttcct caattacaag gacattgtta
     9781 aatatagatg ttaaatattc attgattcgt tggtagtcca tttttcatat ccctccttct
     9841 tcaaaaaact tttacaatca aaacatttga cagaaagaat tatatcaaaa ttcaaagaat
     9901 gatgcaagta ttttttattt tcctgtaaat ttaggtcttc ttctctccga atgagctcgc
     9961 actccttctt tgaaatcctc tgtttgagct aaggatttct gtaggttcag ttctaaagta
    10021 gcgtaaccct gccagtcttt aaattggctc tcccaaacca acttcttaat ggcagcatag
    10081 gaattacttg aagcacgtct taatttttta agaagctgtt ctctcgtctt ttcaagtttt
    10141 tcagcttcag aaacgcggta aaccaacccc cattctaggg ctttttctgc cgttaaagcc
    10201 tctcctgtca tagctaattg agcagcacgc gtcacaccga tactgcggct caagagatga
    10261 attccccctg catctggagc caaaccaaca ccaacaaagg cttggataaa cttagcctta
    10321 tccgtcgcca aacagaaatc tgccgcaaca gccatattcg ctgcggcacc tgcaacagca
    10381 ccgtcaactt ccattaaaac aggtttggct atttgcttga ttttataaga aatcgtattg
    10441 accaactctg cgatttttgt caatgatgga atatcatcct catccactgc ccgcttcatc
    10501 tctaccaaat ctcccccaac tgagaagacc tttccattgg cattgattaa gataaaatgc
    10561 acagctggat tttcttctgc caaagtcaga gcttctaaaa tctcctcaca catgggaata
    10621 tgaaaaccat ttgcgacctc aggacggttc aaggtaagga ttgccaagtc ctcttcaagc
    10681 tgataaataa tgtgttccat cagggctcct ttttatttta taagcagttt atactcttcg
    10741 aaaatctctt taaaccgcgt cagcttccat ctgcaacctc aaaacagtat tttgagctga
    10801 cttcgtctag cttcttagtt tgctctttga ttttcattga gtgttaaatt atttcactgt
    10861 caaagtatat cttttttagg agcagaaagc aagaaaaaat cgactgaaag tgtctcagcc
    10921 gataagaaag gctcgcttta ggctagaaag catcttattt tcttcattga aaaaagcctt
    10981 tctttctgct ataatcgtat aaaatactta ctttaggagt tcttatgaaa gttgttaaat
    11041 ttggaggtag ttctcttgcc tctgctagtc aattagaaaa agttttaaac atcgtcaaaa
    11101 gcgattcaga gcgtcgtttt gtagtcgttt ctgcgcctgg taaacgcaat gctgaagata
    11161 ctaaggttac ggatgccctg attaaatact accgcgacta tgttgcgggt aacgatatta
    11221 gcaagagcca aagctggatt atcgaccgct atgctgctat ggttagtgaa ttgggactaa
    11281 aaccagctgt gctagaaaaa atttctaaaa gcattcacgc cttggccact cttcctattg
    11341 aagaaaatga atttctctac gatactttcc tagcagccgg tgaaaataac aatgccaaat
    11401 tgattgctgc ctactttaac caaaatggta tcgatgcacg ctatatgcac cctagagaag
    11461 ctgggattgt ggtcacaagt gaacctggtc acgctcgcat cattccatca agttatgaca
    11521 agattgaaga attgacaaac accaatgaag tccttgtcat tcctggtttc tttggtgtca
    11581 ctaaggaaaa tcaaatctgt actttctcac gtggaggttc tgatattaca ggttctatca
    11641 ttgctgctgg tgtcaaagct gacctctatg aaaactttac ggacgttgat ggtatctttg
    11701 cagctcaccc tggtattatc caccaaccac actcgattcc tgagttgacc taccgtgaaa
    11761 tgcgcgagtt ggcctatgca ggcttctcag tccttcatga cgaggctctt cttcctgcct
    11821 accgtggaaa aattcctctg gttatcaaga ataccaacaa ccctgaccat ccaggtactc
    11881 gtatcgttct aaaacacagt aatgatgaat ttccagttgt gggaattgct ggtgactcag
    11941 gctttgtcag cattaacatg tcgaaatacc tcatgaaccg tgaggttgga tttggccgca
    12001 aggttctgca aatcctggaa gaacttaaca tcggttggga acatatgcca acaggtatcg
    12061 acgatctttc tatcattctc cgttctcgcc aactaactcc catcaaggaa gaagaaatcc
    12121 tgcgtcagtt ggttcaaaag gctaaagtag atcatgcaga aatcgaacac gacctttcta
    12181 tcattatgat tgttggtgaa aaaatgaaga gccatatcgg agtgactgct actgcgacac
    12241 gcgctctatc tgaaaacaaa atcaacatcc agatgatgtc tcaaggttct agtgaagttt
    12301 ctattatgtt tgttgtcaat aaagaccaag agaaagcagc aattaaagcc ctctacaatg
    12361 ccttttttgg agaaagtaag gaagactaag catggctcaa tcacttaaca aaacagtact
    12421 cctcagtacg acaggcactt cctacctctc tatcgctggg aaagttggga aattccttgt
    12481 cggagatcag gctttggaat tttacccaga tgtcaatgtc gaacaattta tccagattcc
    12541 ttggagccat atcaatcaga ttggagccaa tgtcactgga cgcaaaatca gccgccactt
    12601 cgaagtcttt acagacaaag gaaaattcct ctttgcttca aaagactcag gtgccattct
    12661 caaaattgca cgcaaaaaac taggcaatga caaggtcgtc aaacttccga ccctgattca
    12721 gacaattagc caaaaattta aaaatctatt tgcaaaaaag tagaaacttt agtataatca
    12781 tagcaacgga taagtaggtt atcttcttct ttcagaaagt ctgcgggtac tgcgagcaga
    12841 taggagggat aggtgaaatt ctaccgttag taacaattac atacacaatc aagtgcacac
    12901 ctgtgaagtt ggatggaacc gtggccctgc cactccaacg ttttgtcagg cgtgcttttt
    12961 tcataaagga gttcttatgt tagatatcaa acgtattcgt acagattttg aagctgtcgc
    13021 agaaaaatta gctacacgtg gtgtagatgc tgctgtcttg aatgaaatga aaaaaatcga
    13081 tgctaaacgt cgtaacatct tggtcaaggt tgaaactctc aaagcagaac gtaacacagt
    13141 ttctgctgag attgcccaag ctaagcgcaa caaggaaaat acagatgaca agattgctgc
    13201 catgcaaaat ctatctgctg aggttaaagc cttggatgct gaattggcag aaatcgatgc
    13261 taaattgaca gaatttacaa cgactcttcc aaatatccca gctgacagcg ttcctgttgg
    13321 ggctgacgaa gacgacaatg tggaagttcg ccgttggggt actccacgcg agtttgactt
    13381 cgaacctaaa gctcactggg atctcggtga agaccttggt atccttgact gggaacgcgg
    13441 tggtaaggta acaggcgctc gcttcctctt ctataaaggc ctcggtgctc gtttggaacg
    13501 tgctatctac aactttatgt tggatgaaca tggaaaagaa ggctatactg aagtcatcac
    13561 accttacata gtcaaccatg attctatgtt tggtactggt cagtatccaa aatttaagga
    13621 agatactttt gaactcagcg ataccaactt tgtcttgatt ccaactgctg aagttcctct
    13681 gacaaactac taccgtgatg aaatcttaga cggcaaagat cttccaatct acttcactgc
    13741 tatgagtccg tcattccgtt ctgaggctgg ctctgccggt cgtgatacgc gtggcttgat
    13801 ccgtttgcac caattccaca aggttgaaat ggtcaaattt gccaaaccag aagaatctta
    13861 cgaagaattg gaaaaaatga cagccaacgc tgaaaacatt cttcaaaaac tcaaccttcc
    13921 ataccgtgtc gttgctctct ctactggaga tatgggcttc tcagctgcga agacttacga
    13981 cttggaagtg tggattccag cacaaaacaa ttaccgtgaa atctcaagct gttcaaacac
    14041 agaagatttc caagcccgtc gtgcccaaat ccgttaccgt gatgaagcag atggcaaggt
    14101 gaaactcctt cataccttga acggttctgg acttgcagtt ggacgtacag tggctgcaat
    14161 tcttgaaaat taccaaaatg aagatggttc tgtgaccatc ccagaagcac ttcgtccata
    14221 catgggtgga gctgaagtca tcaaaccata aaaaataagg tttagctatt tctagctaga
    14281 ccttttttcg taaccaaatc agataagcac ctagtacaaa gaataaaata gttaggcata
    14341 taatggtttc agccaatacc aggtaatcca gaaatggaag tttcaaaatt ccctgagcca
    14401 tcttgagcga ggtcgctgtg ataatggttg ggaaggtgag ggctgagaag gctggttgaa
    14461 aaccttgttt taaaatgttg ggcagacgag ttaaaacaaa gaaaaagaag gattgagaag
    14521 ccaaaatcat gacaatcaag acccaagtcg gcaggctggt tcctcctact cgaactagag
    14581 aagccaagag tagagagaaa ggagcacagt agattccttc ttgtccaagc aaggctagtg
    14641 ggagtggatg tttctttaaa tcgctataaa taaggggata gagatagaag gtcaagagaa
    14701 aaccaaaact caaggtcgca taggcaattt cgataatacc taccagagga taggtcaagg
    14761 cagccactgc tatccccaca tagagaaccg tccagcttgg agtggcatga accctccgcc
    14821 ctggacaagc aaacttgatg gtaaaaccag caatcaaggt caaatccaag agaaatgaaa
    14881 accaccaaat cccttgtgct accaaaggaa gataagagaa tacgcgaaag acataggtcg
    14941 ataaaatcat cccagccata ggaaaggttg ccattcctga caaaagaggg ggcttggtca
    15001 attcttgctt ggtttctttc caattaaaga gatgcagaat tagaaagtaa atccataaaa
    15061 ccaaaccagt cagactaaaa agatgggata gaaccggcaa cgtatctaaa ataagatttc
    15121 cagctcctgc caaacctagc aaacaacctg aaaatactaa ggggagtttt ttcatcctaa
    15181 cctccaataa tcatgttagt ttcagtataa cataaaagcg cttaaatgag gatttaaaaa
    15241 aacgaagtcc gcttatttca gacttcattt tactcagata tgaattaggc ataaggttgc
    15301 aattctggat taattggtgt attagctaag ttgttggcat agttacagag gattgctagg
    15361 ctgacaccaa aaaccacatc caaggcattt tgttgagtgt agccagcttc taaaaactca
    15421 gacaaggctt catctcctac acgacccttg gtattgataa ctgccaaggt aaacttagct
    15481 agggtatcca atttaggatc tgtttcaatt ggagtacgat tgcgaagagc ttgaatcaag
    15541 tcatcattca tctggatttg tttgatggaa aaggctgtgt gacctgcgac acagaaggca
    15601 caaccattgg tcacggctgc cgtgatttgc accacttcac gctcaacggg tgtcaggctg
    15661 ttgcgacggt ggatagatga gacaatttgg taggcttcta aaacagtcgg ggcattggcc
    15721 aagagaccga ttaggttggg aatatagcca ttgttgtctt tttctactgt ttcaagaatt
    15781 tctttcactt ctgctggtgc tgactctact gtatggatag taaatgttgt cataagatac
    15841 ctcttttctt attattgaca ctaatattat tggaaaatct tataaaatcc tgattcctaa
    15901 gtttatctaa gataaagctt tattctctca taagattttc gttgttatat tagtttatca
    15961 cacttccaat cacttgcata atatatatta tatatcaggc tgataaaaat tatttatagg
    16021 caaaaaaatc acacgagctg tgtgattcca ttatttgtca aaatactttt tagtttcagc
    16081 aataacgact ggcgacatga ccaagagggc aatcaagttt ggcagagcca tcaaggcgtt
    16141 aacgatatct gcgataatcc agaccatatc caactcgata aatcctccta acaagaccat
    16201 gagcacaaaa accacacggt agagccagat aaagcgaacc ccaaagagga actcaaaaca
    16261 gcgttctccg taatagttcc aacctagaat cgttgtaaag gcaaaaagta caaggaagat
    16321 ggtcaagagg gcaggcccaa agtgtgaaaa gactgttgag aaagctgact gagtcaaggc
    16381 aaccccattc aagtcaccac tccaaactcc agttaccaag atggtcaaac cagttagagt
    16441 acaaatgatg agggtatcaa taaaggttcc tgtcatggaa atcaaacctt gctctactgg
    16501 ttcatttgtc ttggcagctg cagctgcaat aggagcagaa cccagaccag attcgtttga
    16561 gaacacacca cgcgccacac cattttgaat agccatccga acgctagcac cagcaaatcc
    16621 acctaccgca gcaaggggac taaaagctga ggtaaagact aaagcgattg tgccagggat
    16681 ttttccgata ttaaagaaaa taactgtaag agttcctaag atataaatga gggccataaa
    16741 aggaacaaca gtagttgaaa ccttagaaat agacttgagt ccaccaaaga ctgcaatcgc
    16801 tacaaagaca gacaagacga gagctgtgat ggctggcgaa atcgtcgttg tattttggat
    16861 agattctgta atcgagttga cttgggtgaa ggttccgatt cccaagagag caaccaatac
    16921 tcctgctact gcaaacaaaa cagcaagtgg tcgccacttt tctcccatcc ctagaaggat
    16981 atagtgcatg ggacctcccg ctactgcacc atggtcgtcc ttggtgcggt atttgatggc
    17041 caagagtcct tccgcatact tggtagccat tccaaagaaa gccgccatcc acatccaaaa
    17101 tagagctcct ggtccaccaa ccttgatagc cgtcgcaact cctatgatat ttcctgttcc
    17161 aacagttgat gccaaggctg tacacagagc tgcaaaactg gatacatcac catgtccctt
    17221 atcctggata aaaataagct gaaaggcctt gggcagacgc aaaacctgca agagtcctag
    17281 ccgcatagtt aggtaaatcc ctgttccgac caataaaatc aagaggggcg gtccccaagc
    17341 aaaagcatcg attgatttaa gcaattctaa catttccttc tcctatcgtt tcaaccccaa
    17401 aagaaagagc acatgcaaga tacatgtact ctggaatgct tagataaatg ctaaaaagcg
    17461 gtctatccta gctctgtcct tttacctgag agtttgagca gttgcctgcc ttgccccttc
    17521 ggtgccttta cggtctctcc agagttccgt ccatttacag tcatggaaaa tcaaacgatt
    17581 ccccacttct attaaacttc attcggtgtt ggtatttaat tgattctaat tttacaaaaa
    17641 atgttggctt ttgtcaatgt gtttattagt aaaaattagt tcaacagttt ttactttata
    17701 aagtccagaa tactgctatc ctttaaaagt gacaatagtc gcaccactgc ctccagcatt
    17761 ttgtggggca tagccgaaac tcttgacatg tttgtttctt tgcaagtatt tggtaactcc
    17821 ttcacggatg actcctgttc cgataccatg gatgatatca acttgagcca tattgttaag
    17881 caaggcttgg tcgatgaagg tatctagctc attcatggct tcttcatagc gcttgcctcg
    17941 aagatccagt ctagcttgag gtcctcgccc agaagttcgt ttcacaacat tgacctgttt
    18001 cttcttgact gctttttctt gctgggcttg aacaagatca aactctttct cttccaaggt
    18061 catcttaatc aagccaactt gggcttccca gcggccgtcc ttgagttgac tggtcaaggt
    18121 accacgctga ccataactga gaaccacgat atcatctccc acctttggag ctcgtttttt
    18181 cttggccttt tgaaggacct tgtttttaga caagtccact ttttcaggag ccaatttttt
    18241 caacttggcc ttggcttcaa tgatttcgtg gggcttgagt tgggatttac tgtggagatt
    18301 tttgagaatc tggtcacttt cacttagggc catatccaca atctcagcag cctgttcacg
    18361 cgccttgtta agctcggttt ccttttcacg attaagctcg ttgtagagtt tttttagcgc
    18421 acggttcatc ttgagatttt cttgctccac ctcacggata ttgtccaagc gtttgcggct
    18481 ttccagcgtc tgctcttcta attgctcaat gatacgattg acgtcattgt cctgatcgat
    18541 ctgctgactg gcatctccta cgataacttc agataggcct agacgtttgg caatttcaaa
    18601 ggcattactt cggccaggaa caccctgcat aaagcgatag gtcgggcgaa gagttgcagt
    18661 atcaaactcc atactggcat tttgcacaaa ggctgtctca ataccgtagg ccttgagttc
    18721 tggatagtgg gtcgtcgcca tggtcttgat ttgacgcagg cgaaggtcct ccagaatagc
    18781 catggcaagg gctgctccct cttggggatc agtaccagcc cccaactcat ccaaaagtaa
    18841 gagtgaatgt tggttgacct taccaagaat atccacgata ttggtcatat ggctagagaa
    18901 ggtagacaag ctctgctcaa tagactgctc atctccaata tcagcaaaga tttcttcaaa
    18961 aataccaaca cgacttccct tgtctgctaa aatcggcaat cctgactggg ccatgacctg
    19021 tgtcaagccc agagttttga gcatgatggt cttcccacct gtattgggac ctgtaatgac
    19081 aatagctgtt aaatcttgac caaaatagac atcatttgcg acggcatttt tgaccaaagg
    19141 atggcagaca tggagcagtt gaatctcttg attttctgac agctgaggca cgactgcttg
    19201 tctttcttgg ataaatcgaa ccttggcacg aatcaagtcc agatgaccga taatccaagc
    19261 atcattagca atctcagccg catgagggcg gacacgctca gaaatttctt ggagaatgcg
    19321 aagcatttca tagcgctcat ctgctcgcag actagcaatt tcttcgctca gtttgactac
    19381 ctcacgtggt tcgatataga cggtgtttcc actagcagaa atatcatgaa cgacacctgc
    19441 aatcttattg cggtaggtgt ttttgaccgg taaaacctga cggccatttc tgctaacaac
    19501 aattccttcc gtcaacatct gcgctttttg cttgagcaag tcttgtaaaa catcgcgtac
    19561 ctgactctcg ctatcatgta tttttcgacg gattcgcgcc aattcttcac tggcaaaatt
    19621 ttcaatgaaa cccgcatcat taaaggcctg aagatttcct tgtaattgcg gaaaatcatg
    19681 taatttctca aaccaaaagg ctaattcttc caagctgaca ttttccagat tggcgtaaaa
    19741 actttgaagt tctcggctgg caagaagcac gcgtttcaag agtaggaact cctcgatatt
    19801 gagatccgct cccatctcca acctcttgca gactcctgca atttccttag ttgagagaat
    19861 agtaaaatgc ggttgctcga cgaaaagagc ctgcatttcc ttcatctcag caaaagcctg
    19921 tttgatttta tctgctttgg cagtcggagc cagttgtctc aattgctcca agccctgctc
    19981 ggtcaacaaa tgaggctcaa acaaggcctt gaccttatcg aactctaatg tttctaatat
    20041 tttcttattc atctttattt ccttgtcttt gaatgtctag gtgtggtagc tttttacatt
    20101 ctgatagatt cgagtcaaat ctgtaaacaa agggctagga aaactcctgc cctttttatc
    20161 cgattaaatt tgtcacccag atttgtttga gccaactggt tgttatcggt atgctctgga
    20221 tgatatgttt tgcgacgata ctcttttcaa gaggattttg tataactgcc atggggatgg
    20281 tcgccaagat tgtcaaggcc atttgcaaga caaataaggt caccaacatg gacaagatac
    20341 ctgctgaaac ttggaacaac ttaccaccca gttttttgct aggaatcaag tgtaagagaa
    20401 gaccaagcaa acgaccaatg ctatagacaa tcccaaatac aagcaagtag ccgatacctg
    20461 cataaaagac cttatccagc tgaaagagtt gatccgatgg gaaaaagaaa gtcccctgat
    20521 cttcctgcga atttgcataa gggagcaata aatggaattg ctctccaagc cccttataaa
    20581 actgaccagc cataaaagcc gatgccatgg ctgaaatcag gtaataaacc tgtaagagca
    20641 ggcctctccg atagccgata taaaatcccc aaaccaagac caatagaaga aggaatgaaa
    20701 tcataaggaa tcctcaatct tgctctgttc ttgcttacaa gtcacaagct tgtgacggag
    20761 ttcttctagc tcttgctcct tatcgtcaaa ttcaatctca cggctgagct gagttgataa
    20821 acagttgact gccaacaaaa gagcgattgt ttcatcatct gcgctaggca tttgttcttt
    20881 aattgcttgg tatttttctg tcgcaacctt agcgatttcc tccataaaaa ggttatcatg
    20941 ttcgcttgtc aaggttaacg attttttccc gaatgtaaat ttgaatcgat ttagatttgc
    21001 cataaaattc acctcacgat attataccaa aattcgctaa ttttgtcagt ttttacaaat
    21061 tttactgctt ttgtggtaca atagaaacta tggcaagtat cacactcaca ccaagcgaaa
    21121 aggatattca ggcttttctt gaacactatc aaaccagtct ggctcctagc aagaatccct
    21181 atatccgcta ctttttgaaa ctacctcaag caacggtttc tatctatact tctggaaaaa
    21241 tcttgcttca gggtgaaggg gctgaaaaat acgccagttt ctttggctat caagctgtag
    21301 agcaaaccag cggacaaaat cttcctttaa ttgggacaga tgaggtggga aatggttcct
    21361 actttggtgg gcttgcagtt gtggctgcct ttgtcacacc tgaccagcac gactttttac
    21421 gaaaactcgg tgtgggggat tctaagactc tgaccgacca aaagatccgt cagattgctc
    21481 ctattctcaa ggaaaaaatc cagcaccagg cactccttct ctcacccagc aagtacaacg
    21541 aggtcatcgg agaccgctac aatgctgttt cggttaaggt tgccctccat aatcaggcta
    21601 tctatctcct ccttcaaaaa ggtgttcagc ctgagaaaat tgtgattgat gcctttacca
    21661 gtgctaaaaa ttatgacaag tacttggcac aagagaccaa tcgtttcagc aatcctatca
    21721 gcttagaaga aaaggctgag ggcaaatact tggctgtcgc agtttcttct gtcattgcgc
    21781 gtgatctctt tctggaaaat cttgaaaatc tgggacgaga actgggttat cagcttccaa
    21841 gtggagctgg aacggcttct gacaaggtgg ctagccagat tttgcaagcc tatggtatgc
    21901 agggactcaa cttctgcgct aagctacact ttaaaaatac tgaaaaagcg aaaaacgctt
    21961 agaaaggtaa gttatgaatt tatttaaaaa tttcttaaaa gagtggggat tattcctcct
    22021 gattctgtca ttactagctt tgagccgtat ctttttttgg agcaatgttc gcgtagaagg
    22081 acattccatg gatccgaccc tagcggatgg tgaaatcctc tttgttgtta agcacctccc
    22141 tattgaccgt tttgatatcg tggtggccca tgaggaagat ggcaataagg acatcgtcaa
    22201 gcgcgtgatt ggaatgcctg gcgacaccat tcgttacgaa aatgataaac tctacatcaa
    22261 tgacaaagaa acggacgagc cttatctagc agactatatc aaacgcttca aggatgacaa
    22321 actccaaagc acttactcag gcaagggctt tgaaggaaat aaaggaactt tctttagaag
    22381 tatcgctcaa aaagcccaag ccttcacagt tgatgtcaac tacaacacca actttagctt
    22441 tactgttcca gaaggagaat accttctcct cggagatgac cgcttggttt cgagcgacag
    22501 ccgccacgta ggtaccttca aagcaaaaga tatcacaggg gaagctaaat tccgcttctg
    22561 gccaatcacc cgtatcggaa cattttaaga aacctaagag gccgagaatc accaatctca
    22621 gcctcttctt ctatcgtgag aagtgattgt ttattgacaa atactcaatg aaaatcaaag
    22681 aacaaactag gaagctagcc gtaggctgct taaaacagtg ttttgaggtt gcagatggaa
    22741 gctgacgtgg tttgaagata ttttcgaaga gtataaaata aaaacaatcc caactctcac
    22801 ctattcatac aaaggaattt tatggaagtt tatttttcag gaaccattga acggattatt
    22861 tttgaaaatc ccagcaattt ttatcgcatc ctcctcctag aaatcgacga tacggacgca
    22921 gaggattttg atgattttga aatcattgtc acaggaacca tggctgatgt aattgagggc
    22981 gaagactata ctttttgggg gcaaattgtc cagcactcca agtatggaga acaactgcaa
    23041 atcagtcgtt atgatcgcgc aaaaccaact agtaagggct tggtcaagta cttttcaagt
    23101 agccatttca aggggattgg tctcaagaca gctcagaaaa tcgtggatac ctatggcgaa
    23161 aataccattg acgaaatttt gcaacaccca gaaaagttag aaggcatcgc aggactctct
    23221 gccaaaaatc gcgaggcttt cgtctccact ctccgtctca actacggtac ggagatggtt
    23281 ttggccaaac tagccaacta cggcattccc aacaaactag cctttcagat tcaagacttt
    23341 tacaaggaag aaacccttga tgtggttgaa aattatccct accagctggt tgaggatatc
    23401 aagggtttgg gctttaccat tgctgaccaa ctagctgagg aactaggcat cgaaagtcag
    23461 gctcctgaac gcttccgcgc cggtctagtt cacagtcttt ttcaggcctg tatggaaaca
    23521 ggggacacct atgttgaagc acgggatttg ctggaacaaa cccttactct ccttgagtct
    23581 tcccgtcccg tggaactaga ccccagccaa gttgcccaag agctctccta cctgatcgaa
    23641 gaagacaagg ttcagcagat tgataccaag atctttgaca acagcctctt tttcgctgag
    23701 gaaggtatcc gcagtcactt gattcgtatc cttgaaaaag gagaacagaa gagacaagat
    23761 ttagaaacta ttcaaaagca tatcactact gtcgagcaag aactggggat tgagtatgat
    23821 aacattcaaa aacaagctat ttgtgacgct atccagaaca aggtctttat cctgacaggt
    23881 gggcctggta ctggtaagac aactgttatc aatggaatca tcgctgttta tgccctttta
    23941 gaaggacttg acttcaggaa gaaaagcaat ctgcccattc ttcttgctgc tccaactggt
    24001 cgagctgctc gtcgcatgaa tgaattgaca ggtttgccta gcgcgaccat acatcgccac
    24061 ttgggaatga caggtgacga tgataccagt catctggaag attacctaga tgctgagttt
    24121 atcatcgtgg atgaattctc tatggtagat acttggctgg ccaatcaact cttctccaat
    24181 atctcttcta acagtaagat cctcatcgta ggtgacagtg atcagctacc ttctgtcagt
    24241 cctggacagg ttctagcgga tctgcttcat attcctttga ttcctcagac tcgcttggaa
    24301 aaaatttatc gacaaagcaa agaatcaacc atcgtcaccc tagctagtca gattcgacag
    24361 ggcatcttgc cagctgattt cacccaaaaa aaagctgacc gttcctactt tgaaattgct
    24421 agtggccata ttcctgccac cattgaaaaa atcttaggtg ccgccctcag aaatggtatt
    24481 cctgcccgtg atatccaagt tctggctcct atgtaccgag ggacggcagg gattgatgct
    24541 atcaatcagc tcatgcaaga cctgctcaat cccccacaaa aagatcaact cagttttgaa
    24601 gcccctcagt gccactatcg taagagagac aaggtcattc atttggttaa cgatgctgaa
    24661 atcaatgtct ttaatgggga tttaggagct atcacagacc tgattcctgg taaatacacc
    24721 gaatcgaaac aagacgagat tgtcattgat tttgatggta atgaagtctc ttacccccgt
    24781 aacgaatggt acaagattcg cttggcctat gccatgagta ttcataagtc tcagggaagt
    24841 gagttcccag ttgtcatcct accgattact agtgctagcc gacgtatgct ggagcgaaat
    24901 ctcatctaca cagccattac acgtgccaaa agcaaactca tcttactagg cgaattacaa
    24961 gccttcgact atgctaccca acacatcgga actgcccgaa aaacctatct gattgaacgc
    25021 ttcagtgatc tactggagaa tgttgaagaa aagcaacaag ctgtctctga aacagtcaca
    25081 tcaagtgcct ctgaacaatc ctacatccta accgaagaaa actgggacag cattccagcc
    25141 atgattggga ttacagacac agacctcaaa gagatttttg gaaaatagta catcagaaaa
    25201 cccacctgaa ttggtgggtt ttctgtttat taagattatt ttactgttgc tgtgcttgtg
    25261 atcaattcaa cagctttttt gatagtgata tcatgtttca acatgtcagc tgaaagcaag
    25321 ttttgaactt gtgcaacttc catgttgtag tctgctgcca attgctcaac ttctttttgt
    25381 atttcttctt ctgaagcatc aaatccttca gctttggcaa ctgcttcgat aacaaggtta
    25441 gtcttagtac gtgactcagc ttctgcttgg tattggttgt gaaggtcttc ttgagtagtt
    25501 ccagtgattt ggaagtacat gtcagggttg atcccttgac gttgcaagtt cccaaggaat
    25561 tcatttactg aacggtgaac ttcttcatgg atcatttctt ctggaagttc tacgatttca
    25621 gcgttttcta cagctgtatc aattgctgca ccttcaactg catctttgta agtttcttct
    25681 ttagcagcag ccaattcttt gcggtatttt tctttcaagt cagcaagtgt ttcaacttct
    25741 tcatcaatgt cttttgcaag ttcatcgtca agagctggaa cttctttagc ttttacttcg
    25801 tggatagttg tcacgaattt agcttcttta cctgcaaggt cttctgcttg gtagtcttct
    25861 gggaatgtta cgataacatc aacggtttcg ccagctgagt gacctaccaa ttggtcttcg
    25921 aaaccaggga tgaattgacc tgaaccaagt ccaagtgaga agttttcacc ttttccaccg
    25981 tcaaattcaa caccgtcgat agaaccaacg aagtcgatca caacagtgtc gccgttttca
    26041 gcagcagctt ccttgataac caattcagcc aggttgttgc gttcgcgttc gatacgctct
    26101 tcgacatcag cgtcagttac ttctttttct acatcaactg atacttcaag gtttttgtag
    26161 tcacccaatt ttacttcagg ttttgtaacg acttcagcag cgataaccca gtcttgacct
    26221 ttttccattg aagttacgtc aatttttggt tgggcaacca cttcaagacc agcttctttt
    26281 acagctgctt cataagcgtt tggcaaaaga gcgttcattg catcttgata aagagcttct
    26341 tcaccaaatt tttggtcgaa gatagggcgt ggaaggtgac ctttacggaa acctggaaca
    26401 ttaagagatt tcttcactga cttgaagaca cggtccaatt ctggtttgat ttggtcttga
    26461 gagatagtga aagtcaagac accacggttt gtttctttgt tttcaaatga tacagacatt
    26521 ctgtcatttc tccttaaaat tttttaaata cagtctatta taacattttc tataaataaa
    26581 atctagacta atgcagccaa ttatagacaa caagcctttt tcctaactaa aacactcata
    26641 aagtatagac aattttagac tactttggat atcttttggt tagtcatttt ccaaaactaa
    26701 tttatctaat ttttcagtta tatagtagat tgaaactaga atagtacacc tctacttcta
    26761 aaacattttt agaaatcgat ttgactgtcc cgatcgattt gtcctgttct tgtttcattt
    26821 tactatatag atcgcattcg aaagaattcg ttccaaaatt gcttggttcg ttcttctctt
    26881 ggacgactaa agaattgatg ggcattattt ttttcaacaa ttttcccact gtccataaaa
    26941 ataacatgat gggctacatc tctagcaaaa cctatctcat aaagctgatc aaaaactcaa
    27001 tctgaggaga aaatccaata aggctttcca taataaagga catcctatca agatttttga
    27061 acacccgata ggctgccttt ttccgatttt gaagactttt tgtccagctt cttttacctt
    27121 ataaataaca acaaaaatca aagacaagct agaaagatta ccgcagataa ctcaaacagt
    27181 gttttgaggt tgcagataag actgacggag tcagctcaaa gcactgcttt gaggttgtag
    27241 atagaactga cgaagtcagt aacatatgcc taagacaaag cgatgctaac ctgatttgaa
    27301 gagattttcg aaaaagatta aatatactct acaatttgct caatcaattc ttggtcgtct
    27361 aaacctgtaa cttgtataac aacatctttg actgattgtt tagccaacaa ttcacctaat
    27421 cgaatacttt cttcatcatt tacatcgcga tagtcaaagg catagccaac tgttttaagt
    27481 aggtttttat atgacaaact gagttctttc aattcacgta tcggccggat gaatcgttca
    27541 ttatagccta attttcggat tggagtgcga gctacgcgac taacctcgtc cgctatgaaa
    27601 gggttttcaa accgttctat aatgactttg tgataattct ccaattcttt tttatcaaag
    27661 ttccatttgg caatcaagag actccgaatt tcagctaata cagattcaat ccgagatttg
    27721 atattaggat tttgaagagc ttccaaaatt gtcttggcac cataatgcgc accaatgtaa
    27781 gctgaagttg catgtccaga attgactgaa aaaagttttc gctcaataaa gggttctaaa
    27841 tcttcttcat aatgcacatc ttttagacgt aaatctggat ttttaagacg cttggtttcc
    27901 acgacccatt cattaaaggg atcgaccaca acaaaaaggg aatcttcgtg actttgtgct
    27961 ggaacaatcc tgtctactgc agcatttgga aaacctatgt agttatcagc aaatgtcaaa
    28021 ccttccggac ttaaatattt cttgacttct tgataaagaa attgagaccc gccaatcata
    28081 ttttcacagg ccataacatc caatgcctgt gtatttcctg caactcggcg agcttcgatt
    28141 cctttggcta gaagttcggc gataaaaggg agtatattag gtccgattgc agtagtaata
    28201 atatccgtct tttgaatcgc ttcaatgact tgctcaggat gttctttgct attaatgcca
    28261 gccacattag ttacttctat acgagactgt cctttctgtg caatttcaat ttcatacttg
    28321 cccttttcat ttagagcatg aattatctga ttattgacat ccacaaaatc aatatggaaa
    28381 ccatttttaa atagaatttc acctataaaa ccacgaccga tattaccggc accaaaatga
    28441 acagaatgtt tcattcaatt tctccttttc ctatttgagg gacatatata ctagatgaca
    28501 aatgacgaaa ttcaattatt caacagcatc aaataagcgc aatacttcct cttttgactg
    28561 agcacctgct agtttaagaa cattatctac atctgcacag aagatagaaa ttttctgaat
    28621 aatttctaag tgttcattac caataccagc aataccaaaa agaaccgttg ccacttgagg
    28681 gttagataca ttcccaaaat caacccctct agggacttga acgactgtaa taccagactt
    28741 gaggacatca ttttttgctg catctgttcc atgcggtatg gcgataaagt tacccatgta
    28801 aacagatagc tctttatctc gctcaatcat ggcttcaata tagtcttcat taacatatcc
    28861 actctcataa agaacttgcc cacaataaca aatagcttcc tccttgttag aaaattgttt
    28921 attaagctta atcaaatgtt tttcaagttt catattagtt ctccaatttc ttaatttttt
    28981 cgttaaaaat agtatttagc atctgataaa taatggattg atttcccgtc ttgtaaatct
    29041 ctgtataaag atgattttca ataatcgact gactgatagc tgtcattaaa tctctcgctt
    29101 cctcgctagc ttctttagac attagcatta gcagacacct tttgacctct tcttcctctc
    29161 gtttcattga caatgcggag ataggtagtt tgagttcaaa catagtaaaa ctatttgttg
    29221 ttactttgct agactgacta tgtaaaagca ccagaccagt attaggaata gccataggac
    29281 tattctggaa gtgagataac aattttcttg ttaggtaatc tctgtcactc acattcttct
    29341 gatattggat gatttgttct accgtgtgct caaatgattg attattctcc aattgaacca
    29401 actcgaattg actcaaaagc tgactactag atattaaata atcttgcaag tcataacttt
    29461 tctctggagc gatagcatca cgcgcgacaa ttgtacgatg tgcctgtaca tactgaagtc
    29521 gttcctgtaa ttcaagcaat tctttgacgg ttggaaaact agaaattaca tcgatttcct
    29581 gattagtcag cggcttggta gataaaatat aatcatactg actgagatca atactgtggt
    29641 aatctactag agactgaata tctatcaact ctacaaaagg agcaacactc ttaattttac
    29701 tgactaataa atctctagtg acccgacgtt catccgttaa aagcaaaaca cggactggat
    29761 aaatctctgg actacggcct aagctagaga taaaatgtag ggcaatcatg ccatactcat
    29821 actctgtatg aagatatttc ggaaaaatat cattcactaa aagactgatg actgtataaa
    29881 gaaatttatt cctttcaact aaaatctgga cagattctgg caaattttca ccctgaaaaa
    29941 ggatagggac gcctaaactg agccgaatat gatggaaaag aaaattgaat aaaaccttgt
    30001 ccttaaaaaa gtcaatcttg gtatacatgg aaaccgtatc aatcagattt gaaatattgt
    30061 agaaaaattc accatcaaat ttctccgtaa agagcggatt gtcctgacgt ttaatgatta
    30121 attcatccaa gatgctcgca aaatagataa tttcctgaat actataaaat tgtgcagtct
    30181 gcttagagta agcttgaaaa attttttgag aaatttccaa agcctgctta ctagtattag
    30241 gtgaattttc aatgttttgc tcctgaccta taagagataa caagatcgca aaaaacatct
    30301 tcatcctagc atccatatct ggaaaacctg acagttgctt attaacaatc tgactggcca
    30361 gcctagttct atctgcttct aaaatatcaa agctcccaaa attaccggtt gaaaaatctg
    30421 ctactgagat acagtttgtc agtaaaatag ccaaaaatct tctcttacca actgaatcac
    30481 cagaaatccg ataacctttt tgtcgttcaa ttttcagatc aaagtctaaa agacgcttat
    30541 caatatctga aatatcctga ataatagtta cattactgac tttcgtgcac tcttgcaatg
    30601 cttcattggt gacaaaaccg ctctcagtca gaaggcgata ggtaatcaac tcttgtcttt
    30661 cttggggact atactcaact aacacttcaa gttctgtcgg caaatcatcc aactctccag
    30721 tcaaaatata gtatttccca tgcttcgtta tttcgattcc atattgctcc atgctatctg
    30781 tcaaatctga taaagttcga taaattgttc tagatgaaac ctgtaagatt tcagtcatat
    30841 cttgcattga aagcttccct acatgtagga aagccttcaa taattgttct tctcgtttgg
    30901 ttaatagcat tcgtaattta gaaacctcta gttctatttg tacattctag cagccatttt
    30961 gtcatattct ggtgttgtta ctaaactatc cacaataaga aattgagaat tcggtgctgc
    31021 ttgctgcact tctgcctgta aagaaatagt tgttacaatc attatgtttt tagaattaaa
    31081 ttcacctaat tctgaaattt tggcagtaga aactggaata cgaatattct tgtttctaaa
    31141 gatagcccga atcgtttcac agcccatagt tgcagttccc tgtgctttac cataagcaac
    31201 tactacagca tcaatatggt taaggtcaat ttcctgacta tctactggtg ctgaagttgg
    31261 tatatctcct tcaatttctg ctattggaaa agctcctgtt aatgaagcta caatttcatc
    31321 ataacgaggg gacgctaaga aattatcaac agaaacatga atagcacttg gactcttgtc
    31381 tttagctctt ggtgtcagtt cttcctgagt aacaattaat gtttttggtg tatcaagcaa
    31441 atttgagatt gcctgattag atactggaat ctctagacct gcttttttaa ccttatctcg
    31501 aagaatacta gctcccatag cagagcttcc cataccagca tcgcaggcga aaatgatttt
    31561 ttccactgag tctgtcgaaa caactgcatc aacagaagtt gatactaact gacctttaga
    31621 ctgagcctta gctgcttggg tagccgcctg agcagcttcg agcgaatcct cagttgactt
    31681 gtctgcatga agaataaggg ctgctacaag gaaagaaaca actgctgcca ctaaaacacc
    31741 taaaagaaca tttagatgag gccaaacacc ttttggcgcc gtagccataa tcgcaataat
    31801 agaacctggt gaagctggag atttaagacc agcgtctaag agttgaaaag taaaagttcc
    31861 agagatacct cctgccatag cagctaaaaa tagagtaggc ttcatcataa cataaggaaa
    31921 gtaaatttca tgaatccctc cgaagaaatg aataaccatt gccccccaag aagaagattt
    31981 agcagaacct ttaccgaata cagcataagc taatagaatt cccaggcctg gtccaggatt
    32041 agcttccaat aggaagagaa ttgacttacc agcttgagct acctgttcta ctcccagagg
    32101 agtaaaaatg ccatgattga gggcattatt gaggaaaagg actttagccg gttcgatgat
    32161 aatattagcc ataggaagga ggcgagcatt gacaatagcc tcaacaccat tcccaacagc
    32221 tccagtaaga gtcgatacga ctggaccgat tgcgtagaaa gccaaaagca ataatgcaaa
    32281 accaacgaga ccagctgaga agttattaac taacatttca aatccgggac gaattttttc
    32341 ttggaacttc tcatcaaatt tcttgatagt ccatcctccc agtgggccca ttaccatagc
    32401 tccgataaac ataggaacac tagaacctgt aattgcacca acagtagcaa tagctcctac
    32461 aacggcacca cgttggccat ggatcatata tccacctgtg taaccaatca ggattggcaa
    32521 taaatacgtt aacataggac caacaacagt agctaactgt tcatttggca gatagccatc
    32581 agcgataaag agggcagtca atactcccca agcaataaat gctccaatat tgggcataac
    32641 catatttgaa agcgatgtcc ctagtttttg aaccctgact ttcaatgata ctttttcttc
    32701 cattagatca tcctcctttt cttaaaacta gtatatacaa agttaaaaac ctttaaaact
    32761 aaagttttgt cacagatttt gtgtcaaaac attacttttg acgaggctgg gcaaaaaggc
    32821 ttaaaaatta taaaacgcat catatcaggt gtacatgaac tacaccccaa aagttagaca
    32881 gaaaaaatct aacttttggg gtgtttttat tatgaaatta acttatgatg ataaagttca
    32941 gatctatgaa cttagaaaac aaggatatag cttagagaag ctttcaaata aatttgggat
    33001 aaacaattct aatattaggt acatgattaa attgattgat cgttacggaa tagagttcgt
    33061 caaaaaaggg aaaaatcgtt actattctcc tgatttaaaa caagaaatga ttcataaagt
    33121 ctgacatgaa ggctggacta aagatagagt ttctcttgaa tactgcctcc caagtcgtac
    33181 gatacttctt aactggctag cacaatacag gaaaaacggg tatactattg ttgagaaaac
    33241 aagagagaga gtacctgaga gcggagaagg ccatcctaaa aaagttaaga gaactccgat
    33301 tgaaggagga aaaagagaaa gaagaaagac agaaattgtt caagaattaa tgactgagtt
    33361 tttgttagtt cttcttctaa aatc
//
LOCUS       DAVDHC010000022        31888 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVDHC010000022 DAVDHC010000000
VERSION     DAVDHC010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31888
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.022"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..2543)
                     /locus_tag="VUR43_001434"
     CDS             complement(<1..2543)
                     /locus_tag="VUR43_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET5413107.1"
                     /translation="MLLTIHDANLQKVAFIDNEKQGTLNYYDDTWTRSLATGSSTFEF
                     TVFKKAVKSDLPLAKAYHHLNEHAFVSFKYKGKSFVFNIIIVEENEQTIKCYCENLNL
                     ELINELANPYKSNKAMTFKEYCEAMDLLNYTHLSIGINEISDYKRTLEWEGQETKLAR
                     LLSLAKRFDAEIEFDTQLNADSTIKKFSVNVYHENDDNHQGVGRVRNDVIVKYGKNIH
                     SITRKVDKTGIFNTIRPTGKMPTVEEEPSGDKGSKSETVKNADGSTTKTTISTASDGT
                     KSKTIVHTKVTKLADKTRITTTTTTRSDGSIEQTVTTSKKGGASTSETKVLKKPNPKE
                     KTNTTEDVLTIEGLDEWEVKNEKGIVEFYQRGQALYAPISMQLYPSTFTHSTGELDQW
                     TRKDFHFETDEPNELRRLGYLKLKKYCYPAITYEVDGFVDADIGDTVKVHDDGFAPLL
                     MIQARVTDQKISFTNPVRNKTIFDNFKALENKLSADIQSAFERLFEAAKPYTIKLSTD
                     NGVIFKNQIGQSLVTPTLYKGGKPVVVGVTWRWALDGEVTTGMTYLVRGSNVTDTVTL
                     TVAAYIGNKEVAVDEISLVNVADGKLGTPGTPGRDGRTPYVHTAWANNATGTDGFSLD
                     SSINKLYIGIYTDFEPNDSTDPKKYKWAKVKGEKGEKGDKGEPGQRGLDGLQGARGEQ
                     GLPGRNGADGRTQYTHIAYSNSADGTKDFSVSASDRAYIGMYVDFNSADSNTPSDYNW
                     TLVKGSDGANGVAGKAGTDGRTPYLHIAYATSNNGSQGFSTTDSTNKTYIGTYTDYTQ
                     ADSTDYRVYKWTLIKGADGTGISNVTNYYLATTVSTGITRTSAGWTTTP"
     gene            complement(2545..4059)
                     /locus_tag="VUR43_001435"
     CDS             complement(2545..4059)
                     /locus_tag="VUR43_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HET5413108.1"
                     /translation="MTKIMTFNGVDMSKFFRITDIIRPIGNKRSVSTDNAPLLGVNIQ
                     QVKIGEKEHIIKFDIKTTNAIEMEQLKHDLAGILNVLEPVKITYGDEPDKYYMGLPVD
                     EITPENLTRWFQRSELKIIIPDGVAHSTTLKNFDIDTNETSAPDRIVFNLTNTGTEPA
                     YPIIRIKHNSENGYIGVVNNRAAFELGNREEADTEKYRDSETLIDYRGTNILKGFQNG
                     TKGVAVTNDNKERLVGTLSTTSMWGRNHIELSNRGTVEKNRNNAQSLTWAIPVDSSGE
                     VGSLNDYLLWRQVFMAAVANQYGFIKVTVSDTDGNFLYGVETYKRYQTLDCEYSFFTT
                     DGKGGYKFIKWWYFTGTGAQVGKLDPFSAEKGWSELKRNDDRVQVFFDGSHYDFIIPE
                     IKDKKSAKIHITLGALRDWPLVSHMYVDEFMYRKDFVTKSRDIPNRYPIGSNVVINSE
                     DDSVYIDGISKVSEVVDGSHWPAIPPGKSQLELYFSRFVKKKPTVTIEFEERWI"
     gene            complement(4056..7337)
                     /locus_tag="VUR43_001436"
     CDS             complement(4056..7337)
                     /locus_tag="VUR43_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HET5413109.1"
                     /translation="MADGKVTIVVDVDGNKVKVLNDELDKAAQKGDRGSDSLKKFAIG
                     GAAFKLASKAVDLLTDSLGGAIQRFDTLESYPRVMQAMGHSTEDVTRSTKKLAAGIEG
                     LPTTLNEVVGTAQRLTSITGDINKSTDLTLALNNAFLASGSSSADASRGLQQFSQMLS
                     AGKVDMQSWKTLQETMPYALQKTAESFGFAGQSAQNDFYSALKEGRITFNQFSRKLVE
                     LNGGVGGFAELAKTNSKGIQTSFGNLKNAVVKGVANTIKALDDLTKAATGKTIAENFD
                     ALKVIINAAFGVIVNVIKASTPVFQTLFSILGTGASVISSLTPVIISLVSALVAMRAA
                     NEAITATKNLINSWQTFKTTATGAIQIINLMTAAQATCGSVTKAQMVANLANNGALTA
                     SNLLYGVLTGSISLQTAATIAATAATTAFKAALTALTGPIGLVVAGVGLAVGALVGLW
                     QWLTAESEETKRLKSEQEELVKSTDQLTDSVKQSAKERQKNLESVKGNTESYQKLADE
                     IVQLSQKTNKTAADKKNLKKKIDALNASVSGLNLVYDKNTDSLSHNNDQIKARISAME
                     AESTWETSQKNLLDIEQKRAEIGEQLKQIAEQRKKWNEESNVSDSVRKERLQELNDKE
                     TELKNTQTELQTEYEKTSQVQQAASEAMAAAAENGSNRQVISYEGMSKAQQKAVDDMR
                     SKYNELLETTTNMFDQIQMKSAISVDEMIANLQKNQEAVNNWATNLNTLAERGVNEGI
                     LAKLQAMGPQGGLYVQELVNASDKKLATLNEVFTQGGESAMNGLTAGMDTGALGITDK
                     IKGIVQSQVSSLQEEIAAADFPEKGKNIPEGVGDGIKAGAEIASEASKNMANDIKESF
                     TSEMDINSPSRVFNEYGGFITTGLAEGVDKGTNQPVSSVTNLANQIKKPFDSLQSDFT
                     YIGEMAMSGLNAGLWSGSGSVMATANSIAERVKATIKSALDIHSPSRAMRDEVGRFIP
                     QGIAVGIEADAGVVEKSMLRLKESMMIDTRPEIALGLNKKLGAQVTVKQSSKQTIAEK
                     IKVTMDKSSELLEKALDVAETAVRRPNEMYLNDGTLVARTGDKFAKYQSEQLRRDNRM
                     KGVLS"
     gene            complement(7330..7899)
                     /locus_tag="VUR43_001437"
     CDS             complement(7330..7899)
                     /locus_tag="VUR43_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413110.1"
                     /translation="MSMKLNDALITNFSIADKEYDIDLSFNKVLDVFEILKEDEMTRL
                     EQAQLIVHLLTGQELYDIKEVVDCWIYIKEHFLEIEKETVQYDLLGNPMPKAKDEEEQ
                     EKLIDFEQDAEYIYASFLQAYGINLLKVQNELTWTEFKALLNALPDNTIMQQIIEIRA
                     WKPEYGGDKNKMRKLQAKYSLGKEGEDNG"
     gene            complement(7912..8400)
                     /locus_tag="VUR43_001438"
     CDS             complement(7912..8400)
                     /locus_tag="VUR43_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413111.1"
                     /translation="MTDIQIELKRTGFPVKIGEVELWFDTSQESLMRFYDMEEELKRR
                     LVQYELDVVSANINNKIERDGVTKEVVAGAIELEKKQLEIQYDLIFGDGTFDKLYSIY
                     PDYNALNNALEQTAIMLHDKLEEVAEQHKTVVKERASHYLNKGKVTPIKNNKKQKKNK
                     KK"
     gene            complement(8465..8914)
                     /locus_tag="VUR43_001439"
     CDS             complement(8465..8914)
                     /locus_tag="VUR43_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET5413112.1"
                     /translation="MTRQKNALRGHFVAPYNGGTEPTTEDTWLELAKWISDVSDDTDE
                     KTDDQAYYDGDGVEETTVVSVKGAYTFEGTYDPDDKAQALIAGMKYKTGDDRKLWHKV
                     VSSDRKKQWVGAATATEIKAGSGAASDYEAFGCKLSYNSTPKETGIG"
     gene            complement(8911..9318)
                     /locus_tag="VUR43_001440"
     CDS             complement(8911..9318)
                     /locus_tag="VUR43_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HET5413113.1"
                     /translation="MRENDFQNVLLKHIKTLNLPVEPRFDYFEDDKDDLVINQIPGGK
                     VDREYMDGTQEVSLPFEIAVKAKKNSVANDTIWLVTSELAKIDLVLPSDNNSYEYMGM
                     EVSRPAMKGKDEQGYYYYTIEIVAKIVIERNKQ"
     gene            complement(9318..9662)
                     /locus_tag="VUR43_001441"
     CDS             complement(9318..9662)
                     /locus_tag="VUR43_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HET5413114.1"
                     /translation="MSIAIKVDLQKAKQKLSNESMTRGKIAVASKILLDNEQYIPLRG
                     GELRASGRIVGQGDAVVYGTVYARAQFYGSNGIVTFRRYTTPGTGKRWDQVATSKHAE
                     EWARAFVKGMGL"
     gene            complement(9662..10033)
                     /locus_tag="VUR43_001442"
     CDS             complement(9662..10033)
                     /locus_tag="VUR43_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HET5413115.1"
                     /translation="MIDKRLLKGIDKRLLKDVLTIKKVADKNDYGDEVYSEPLTIKNV
                     RFDRSVGGSGNRNSKTGTGNSKSRQKQGVIYLYPSLSFVTVDNSWMGAKVNDGIGDYT
                     INGFQTNYYDGEIFSQEIEVI"
     gene            complement(10023..10415)
                     /locus_tag="VUR43_001443"
     CDS             complement(10023..10415)
                     /locus_tag="VUR43_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013794407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413116.1"
                     /translation="MTYLTQEEFDELGFDEVTDFEKLAKRAKIAIDLYTNGIYQKDID
                     FEKEIAYRKSAVKLAMAFQIAYLDASGIMSADDKQLANSVSIGRTSISYSTSQSTLAG
                     QRFNLSMDAENALRQAGFSLVVGVAYDR"
     gene            complement(10458..10691)
                     /locus_tag="VUR43_001444"
     CDS             complement(10458..10691)
                     /locus_tag="VUR43_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413117.1"
                     /translation="MALYKATKNLFFEQLNMDVIVDDIIELDEDYAKEVNKKLKNAFP
                     DVKNVLELVDKNGTLEPEDAPSVDDASQATVED"
     gene            complement(10702..11583)
                     /locus_tag="VUR43_001445"
     CDS             complement(10702..11583)
                     /locus_tag="VUR43_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HET5413118.1"
                     /translation="MPSNQNNAVRRYEKQYAGILETVFGVRAAFSNALAPIQILDGVQ
                     ENSTAFSVKTNNTPVVIGEYKTGENDGGFGDNSGAQSRFGGLTEVKYENTDVNYDYTL
                     TIHEGLDRYTVNNDLNAAVADRLKLQSEAQTRTVNKRIGKYLSDNATKTEALADFTDD
                     KVKALFNKLSAFYTNNEVTAPITVYLRSEFYNAIVDMASVTSAKGATISLDENGLPKY
                     KGFTLEETPAQYFETGVIAIFSPNGIVIPFVGISTARVIEAENFDGVKLQAAAKGGTY
                     TLDDNKKAIYKVTGTIV"
     gene            complement(11601..12164)
                     /locus_tag="VUR43_001446"
     CDS             complement(11601..12164)
                     /locus_tag="VUR43_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HET5413119.1"
                     /translation="MAFTTEELLNLGLTEEQAKSVFALRGKELNEDKSALETIKQERD
                     SLKSQLQKAEEQVEHLKSLENISAEQKDAIDKLQAEYDKYKNEAAAELAQTKKVSAIS
                     LALKDTNAFNPDKLMKFIDVDAIQLDDNGKPQIDEVINGLKESDPYLFKAEESKPSPN
                     ILPQGNPAGEGTSDVDPFQAIIDGYGK"
     gene            complement(12303..13454)
                     /locus_tag="VUR43_001447"
     CDS             complement(12303..13454)
                     /locus_tag="VUR43_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HET5413120.1"
                     /translation="MKKKRKQLTFNDQQFPLQMQGVGDIYEKLQIDIFDRMIKRLKER
                     GSIDLMRNPYIWQLEKLNDMHMLNEQNLKLISERTGIAERLLRDVIENEGLKVYKDTK
                     QQLEEDLNKIPEGEISNGVTDSLEAYSRQAVSDLNLINTTLPKSLQVAYKSIVEETVA
                     QVVAGTKTSDVALHDTIMKWQKNAFTGFVDKGGRHWKADSYARAIIKSTTYKVYNEMR
                     TRPAEELGVDTFYYSMKAMARPACSPLQGQIVTKGAGREIDGITIYSLLDYGYGTAAG
                     CLGIHCGHYLTPFIVGVHELPNLPDYLKNLTPEQAEENARIEAGQRGLERLIKTHKER
                     LHYAHTLQDDKMIQAERLKVRGYQTKIRNLINQHDFLTRDYRREKLYIS"
     gene            complement(13451..13705)
                     /locus_tag="VUR43_001448"
     CDS             complement(13451..13705)
                     /locus_tag="VUR43_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413121.1"
                     /translation="MAKYKKKPVVIEAIRFIGSNYEEVREFIGQNTLCSDLSIVISTL
                     EGDMVAQKGDYIIKGVQDEFYPCKPDIFNATYEVVSEAFE"
     gene            complement(13692..15260)
                     /locus_tag="VUR43_001449"
     CDS             complement(13692..15260)
                     /locus_tag="VUR43_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET5413122.1"
                     /translation="MSLFQKVKDFFSRGRYYMQTSNLNSILEHPKIAVTQEEYDRIKR
                     NLVYYQSKWDDVQYKNTDGDIKSRPMNHLPIARTASKKIASLVYNEQATITTKNEILQ
                     KFLDDMLTNDRFNKNFERYLESCLALGGLAMRPYIDGDKVRVAFIQAPVFFPLESNTQ
                     DVSSAAILTKTIKSEGRKNVYYTLVEFHEWVTADGQETGSTNDKKYYRITNELYRSDV
                     NDVLGQRVNLSELDKYKNLEPVTVFENLSRPLFTYLKTPGMNNKDINSPLGLSIFDNA
                     KTTIDFINRSYDEFMWEVRMGQRRVIVPEHLTQRQYQRPDGTIDFRPRFDVEQNVYMQ
                     IGGSSMDAGGITDLTSPIRANDYILAISEGLKLFEMQIGVSSGMFTFDGQGMKTATEI
                     VSENSDTYQMRSSIVALVEQSIKELCVSMCELGKAVGVYSGEIPELDDISVNLDDGVF
                     TDRHAELDYWAKMVAAGFSTKKRAIGKTLNISGVEAEKELNAINSELLPMNDAELAIY
                     GMHDQNEEEEDGEV"
     gene            complement(15273..16583)
                     /locus_tag="VUR43_001450"
     CDS             complement(15273..16583)
                     /locus_tag="VUR43_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HET5413123.1"
                     /translation="MTFNVQKNINPHFKSVWISSLPYNVLKGGRNSFKSSVIVLKLAY
                     MMIRYIIAGEAANIVVIRKVANTIRDSVFNKVWWALNLFGIAEQFTKTVSPFKIVHKT
                     TGSTFYFYGQDDFQKLKSNDIGNIIAVWYEEAAEFNDQEDFDQSNVTFMRQKHPRAKF
                     VQFFWSYNPPRNPYSWINEWFESIKTNKNYLAHSSTYLDDELGFVTEQMLEDIERIKE
                     NDYDYYRYLYLGEAVGLGNNVYNMSMFHAIDALPSDDKLIGISFALDGGHQQSATACC
                     AFGITAKGKVILLDTWYYSPAGQVVKKAPSQLSKEIYAYMRSVIEKYRVQALQYTIDS
                     AEGALRNQMFLDFGLKWHPVAKLRKVTMIDSFQSLLAQGRFYYLNTENNKIFIEEHKM
                     YRWDEKTIKSDNPSVIKEDDHTCDTTQYFVLDNAKLLGLRVGNV"
     gene            complement(16573..17028)
                     /locus_tag="VUR43_001451"
     CDS             complement(16573..17028)
                     /locus_tag="VUR43_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein"
                     /protein_id="HET5413124.1"
                     /translation="MPRDGTKNLKPVTERTKDEARAISSKGGKASGIARRKKADLKKA
                     FETLLSLDVTDSKIKKQLEEMGMAGNNEALLAFATFQQAVKGNQKATENIIKLTNTKD
                     KYDIQEQKERIKALKYENRERAEAEKGSSETIEIVDAWAEDVRGATDDL"
     gene            complement(17232..17978)
                     /locus_tag="VUR43_001452"
     CDS             complement(17232..17978)
                     /locus_tag="VUR43_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413125.1"
                     /translation="MAQKLTKLKDIFKHVSSIDLGKEILFEDLELYNKETETSKQYQS
                     IEEAENDLYLMEKVNKINFTLGGGRGANFEKGKDGKYPGFRGAGGARDSGSSKALHPA
                     SLNNQGRFSSVEGAIQGFIKKHGGSSTEYSTAVDSQGFAHNYVHGGKNSVQILPISGG
                     FTAIHNHPNGSNFSSTDLHSFAALKGMNTLVATNSSKAYRITKGANFDAKGFDKAVSK
                     SRFTTKDYNKGADLWLKKNAKKYGYTYSYE"
     gene            complement(17959..19053)
                     /locus_tag="VUR43_001453"
     CDS             complement(17959..19053)
                     /locus_tag="VUR43_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000425577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4417 domain-containing protein"
                     /protein_id="HET5413126.1"
                     /translation="MEMLQIEYVDIKSIKPYHKNARHNDGEATEKVAASIKAFGFQQP
                     ILVDDNNIIITGHTRLKAALSLGIDTIPIAHAVNLTDEQIKAYRLADNRVAEYSTWDS
                     ELLNIELSQFETIDMAQFGFELSVTGFNFGNEEEQQEETENEEEDAEDFHRDTTINQY
                     NLFHYDDTRVEGFYNMPKIEGVDHIPKDFQGFNYVLNKPDYSSCVHFFLDDYQFERIW
                     QRPDFYIEKLLEFDSALAPDFSLYLDMPIAMQVWNIYRSRLIGQIMQDYGLTVIPTVS
                     WASEESFDFCFDGLPKNSTLAISTIGVKQNKEQFEVWKNGVTEMIKRLAPKRIVVYGG
                     KVEYDYKDIEVVYFENATTERMKESGTKTN"
     gene            complement(19119..19511)
                     /locus_tag="VUR43_001454"
     CDS             complement(19119..19511)
                     /locus_tag="VUR43_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413127.1"
                     /translation="MTKKKIERLSVIHRREINWLKWYFLRDKKNPKRTILEQKIIVSH
                     IKTDRLEAKFLTNLKKSTEDFIDGSDPKYLRAIKEVYVYENMNVIGACQKILFYSPTQ
                     AYVLLNAWFNDYFRATYTELLENAILDK"
     gene            complement(19508..19747)
                     /locus_tag="VUR43_001455"
     CDS             complement(19508..19747)
                     /locus_tag="VUR43_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HET5413128.1"
                     /translation="MNPEIIDNINKPSHYQGRFGMESIDTLRNFMTPEQLKGFYMGNS
                     LKYILRHQKKNGLEDLKKARKNLDWLIEEMEKEGR"
     gene            complement(19744..20157)
                     /locus_tag="VUR43_001456"
     CDS             complement(19744..20157)
                     /locus_tag="VUR43_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413129.1"
                     /translation="MIPKFRVWVKIGKRMVFSDDILAIDYENKKIVTQQVYFESGLAV
                     ERDIYCYDFDDIELMQSTGLKDKNEKEVFVGDIIKCTKGCPHEVYLEKEYGGTYIGGM
                     PAVYLKGLLSGYVWTEDEEIIGNIYENPELLEDKE"
     gene            complement(20169..20447)
                     /locus_tag="VUR43_001457"
     CDS             complement(20169..20447)
                     /locus_tag="VUR43_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413130.1"
                     /translation="MKRLGIIIGAVFVIVVSPFVVQYGWNEIITTIVPVGKITVWQAL
                     GMDALLSFIWPVLSSKKESEEDYSYAVKSSISKIITCAFLIWLASLFI"
     gene            complement(20574..20861)
                     /locus_tag="VUR43_001458"
     CDS             complement(20574..20861)
                     /locus_tag="VUR43_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413131.1"
                     /translation="MTQTLEEGMKNQSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEEVE"
     gene            complement(20861..21070)
                     /locus_tag="VUR43_001459"
     CDS             complement(20861..21070)
                     /locus_tag="VUR43_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000160162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413132.1"
                     /translation="MTKFVKIQSCYRGNTEDELINIDDISRICLGPNILFLRTPYNLG
                     EHDIFITQNSVDKLLKVLDIIEEVE"
     gene            complement(21071..21583)
                     /locus_tag="VUR43_001460"
     CDS             complement(21071..21583)
                     /locus_tag="VUR43_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET5413133.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQVVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWVGYSPSMAQVVIAVYMNQ
                     FGYEVEEEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDANFGWVFD
                     CEGIEIEEVE"
     gene            complement(21632..21838)
                     /locus_tag="VUR43_001461"
     CDS             complement(21632..21838)
                     /locus_tag="VUR43_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413134.1"
                     /translation="MIEVNIKFDNFEAHGFYQDDTKLGKIRDAIISQMNNGHVVVLGE
                     DRGILLNPKVIKSVQFKVVEDNQI"
     gene            complement(21840..22241)
                     /locus_tag="VUR43_001462"
     CDS             complement(21840..22241)
                     /locus_tag="VUR43_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413135.1"
                     /translation="MKFEFSLPRNTKLKSLNMVINSNDRQHQTDKAKVTKRIRAFAYW
                     HTSMNKDKGRAAFSPSNPCEVTVTIYSPTKSKLDPPNLYPTVKAIIDGMTDAGIWTDD
                     NHKVIKKLSFVYGGLSEEKGHYRLEFDIEEV"
     gene            complement(22373..22696)
                     /locus_tag="VUR43_001463"
                     /pseudo
     CDS             complement(22373..22696)
                     /locus_tag="VUR43_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736105.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22787..22990)
                     /locus_tag="VUR43_001464"
     CDS             complement(22787..22990)
                     /locus_tag="VUR43_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413136.1"
                     /translation="MTKIEIVMVLTTLMSITWAAIVTIHAMQAIKKHKAKVDYYQKPQ
                     VQCEIARHVLKNKWYSDGGEVFR"
     gene            complement(23057..23632)
                     /gene="ssb"
                     /locus_tag="VUR43_001465"
     CDS             complement(23057..23632)
                     /gene="ssb"
                     /locus_tag="VUR43_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET5413137.1"
                     /translation="MINNVVLVGRLTRDAELRYTQSNIAVATFTLAVNRPFKNEAGER
                     EADFINCVIWRQLAENLANWAKKGSLIGVTGVIQTRSYDNQQGQRVYVTEVVASNFQL
                     LESRNSQQNNQGHQDHHGGYQQQGYSNQGSSFQNGNNTGNNFQNGNSYGQQGSFFEGN
                     TTNPVPDFTRDNNPFGRPTNPLDISDDDLPF"
     gene            complement(23622..23798)
                     /locus_tag="VUR43_001466"
     CDS             complement(23622..23798)
                     /locus_tag="VUR43_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413138.1"
                     /translation="MRCFYVSGKIADLDLGSEINAENSFMAAIEFVKRYTDLLKFGSN
                     EIKVSEVEEVQNDK"
     gene            complement(23820..24812)
                     /locus_tag="VUR43_001467"
     CDS             complement(23820..24812)
                     /locus_tag="VUR43_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HET5413139.1"
                     /translation="MVKDVTNSLTEIKVDFQPAVINVDREAIEAQVATAIAQYSGREV
                     TVDNYKEVYEERTRFNKLIGGLDTQRKDFNRQINEPAKDFDKWVKEKVIKPIEAVTDA
                     MSAGLNAIDEHERLMRVDVVRATFEDKCMVAGIEKSTFADKYDEYSLKKYFKTGKYEL
                     KKTTLDEMDGLVLSEFDALEEYKANKQAIQEQAQEYDLPADSYIRHLEDGKSLVDILK
                     MMKTDRDAEIARKEQKEIQEKAKAERLEEIAQSAKKNANANIKAYDAETGEILEQGTI
                     TPEPQNNAREVAKFEPSEPLVKLVRLELHGGLEQWENTQEYFEDNFIGFETLED"
     gene            complement(24815..25516)
                     /locus_tag="VUR43_001468"
     CDS             complement(24815..25516)
                     /locus_tag="VUR43_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HET5413140.1"
                     /translation="MADLTFAELQRKMQIEKQTKQGVKYPFRTAEDINNKFKSLDSGW
                     SVSFPEDDIIQKGDKLYYKAVAVAKRESDGTIEKAIGWAREEDVPIFHTQKGDVKQMQ
                     DPQWTGAVGSYARKYALQGLFAIGGEDVDEYPVEESQEQGQNNQQQKPNNQQAQGQNQ
                     VRYIDNIQYQEINDLINDIAKIKGMPFDTLANYVLSEKLKGLQDFHRVQVGDYEVLKN
                     YLTEQLAKAKAKRGN"
     gene            complement(25522..25974)
                     /locus_tag="VUR43_001469"
     CDS             complement(25522..25974)
                     /locus_tag="VUR43_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413141.1"
                     /translation="MPNWAEGTLKLRGRRENVASALKEMLLGNKGATLEEEYDGTLLI
                     FKNEYDYFYINGTRRAFISSKDIEIWLDDDFVIIELEDFKQAWAASADNYTEISSKFD
                     VDIKIFTFEMGMEFTQEIEISKGEIIKNIVNENFTNYSWDVPFSRLGG"
     gene            complement(26058..26324)
                     /locus_tag="VUR43_001470"
     CDS             complement(26058..26324)
                     /locus_tag="VUR43_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413142.1"
                     /translation="MEAVQIVRIKDVIIEKISGNDEELSHIFGCTKRQAGDMRREMKK
                     LPSQQKHLRNDGQLVTIKGFDAYLQYRGSQSWKKEMAKTVKMTR"
     gene            complement(26399..26617)
                     /locus_tag="VUR43_001471"
     CDS             complement(26399..26617)
                     /locus_tag="VUR43_001471"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413143.1"
                     /translation="MNELVLSNNPSQIELEIKRFLSVPLKLKILRECLLYLFFKMAND
                     TTDITVEKSTVHSSDGARKTVYTVTVYD"
     gene            26683..26892
                     /locus_tag="VUR43_001472"
     CDS             26683..26892
                     /locus_tag="VUR43_001472"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413144.1"
                     /translation="MSFDKNIADKILEFAKLEQTVPVGTSHDFRSEEFDQDDFRDTAK
                     KLISTGQISGHLEEDFSGFYIAFRL"
     gene            complement(26863..27114)
                     /locus_tag="VUR43_001473"
     CDS             complement(26863..27114)
                     /locus_tag="VUR43_001473"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413145.1"
                     /translation="MKQLKLSIKPKQEPTEGQCLNSSGYSVKINDWELGRGVIDFKLE
                     MPADKKPKITITAIPDVMEIDATVIAEIQKLQSESDIES"
     gene            complement(27244..27585)
                     /locus_tag="VUR43_001474"
     CDS             complement(27244..27585)
                     /locus_tag="VUR43_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET5413146.1"
                     /translation="MMVVLANHPNWQVYPDEIAKRKGVNRKTIDKYFKIFEEAGYLRK
                     IRKKPPGNGGSHIFRFFSDVKISDFQFDIMKQRLNLSIKRASMNYNSDIPKSEMSESE
                     MSESEMSDFGH"
     gene            27765..28001
                     /locus_tag="VUR43_001475"
     CDS             27765..28001
                     /locus_tag="VUR43_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413147.1"
                     /translation="MITCHIMIDGRVEPLPMTLPAVPTIGSVIAKSADHKSEHYLVKC
                     VEYVNGHESVNLHVQPFPNQISAVNAVDGFRNSR"
     gene            complement(27930..28196)
                     /locus_tag="VUR43_001476"
     CDS             complement(27930..28196)
                     /locus_tag="VUR43_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413148.1"
                     /translation="MAQENSLIGKYLEISGELAGYIGAETEKDLLVRRAIVINEHIGL
                     CEQAVYVDKKVLDSYWVKIVELSAIPETINSVDSTDLVRKWLNM"
     gene            complement(28243..28959)
                     /locus_tag="VUR43_001477"
     CDS             complement(28243..28959)
                     /locus_tag="VUR43_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HET5413149.1"
                     /translation="MNELINVTLNDNQEPVVSGRQLHESLGVNSRYTTWFDRMKEYGF
                     TEGQDFLPNLGKSTGGRQATDHIIKLDMAKEIAMIQRTERGKQVRQYFIQVEKDFNSP
                     EKIMARALLMADQKVHKLEAQIEADKPKVLFADAVSASHTSILVGELAKLISQNGYKI
                     GANRLFSWMRENGYLIKRKGSDWNMPTQRSMDLKLFEIKETNVQHADGHITVNKTPKV
                     TGKGQQYFINKFLNQEYLTG"
     gene            complement(28961..29146)
                     /locus_tag="VUR43_001478"
     CDS             complement(28961..29146)
                     /locus_tag="VUR43_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5413150.1"
                     /translation="MIYDKIKEIASEKGISIYRIEKDLDLGNGAISKWNNSSPSATTL
                     NSIANYLNVRLEQLLEE"
     gene            29422..29778
                     /locus_tag="VUR43_001479"
     CDS             29422..29778
                     /locus_tag="VUR43_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5413151.1"
                     /translation="MTILDRIRSLANDRKVTLAELERNLNFSNGSLRKWETSTPSGDK
                     IEKIADYFNVSTDYLLGRTDNPTIANKKEQFFFEGKEVDVEELASTAMRFNGKPLTEE
                     DKKAIQNIIEIYLRKQ"
     gene            29800..30180
                     /locus_tag="VUR43_001480"
     CDS             29800..30180
                     /locus_tag="VUR43_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HET5413152.1"
                     /translation="MTEKEFSQNLGIDIEIFEDGLFPDEAFYIPALKTMFLSDAISDE
                     KRVQVALHEIGHRNHAPDTYQLFREKCELEANRNMIHHLMKAELDIAEDATTFNYLVF
                     MEKYNLKTIADEIMVKEEYLALLN"
     gene            30194..30544
                     /locus_tag="VUR43_001481"
     CDS             30194..30544
                     /locus_tag="VUR43_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413153.1"
                     /translation="MNIIAIIIIVIFVGGVIGAVIDNQKKSPEQRERELETFRANQEK
                     KKQEKKQNIITCPNCKSKDVTFLQQDKKAFSVGKAVGGAVLTGGVGALAGFAGKKGNK
                     QWHCQNCGNFFETK"
     gene            30663..31805
                     /locus_tag="VUR43_001482"
     CDS             30663..31805
                     /locus_tag="VUR43_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5413154.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINQKLGEKQHSVSNITFEKLYEEFEENWKHGVKNSTVYASKNVKKEILKQIE
                     GDYLVRNIDRRLLQKVIDQLLQDGRSHNYVSKIKFKLNQIMKFAIRMNYIDTNEMLFV
                     ETPRKVITSDELRKKNTKYLDQKEFKLFIQNLKDEALCDYRITKYIRIAKVLFLTGMR
                     YGELAALNYKEDIDFSKKTIHIKHTYDFRQKERTTPKTIKSDRVITAPQKVLDIIKEQ
                     IIENATNGIDTDFIFINTLGEPITNARIICAWKRHGQKIGIEKNITTHTFRHSHISLL
                     AELGIPLTAIMDRVGHSDSKTTLEIYSHVTQKMVSDISSKLEKIKL"
BASE COUNT         8798 a         6877 c         5196 g        11017 t
ORIGIN      
        1 tgtggcgtag ttgtccaccc tgcgcttgtt cttgtgatac ctgttgagac tgtagtagct
       61 aaataataat tagttacatt agaaatacca gtaccatctg ccccttttat caacgtccac
      121 ttatacactc tgtaatctgt actatctgcc tgagtgtaat ctgtgtatgt tccgatatac
      181 gttttatttg tactgtcagt agttgagaag ccttgtgagc cgttatttga tgtggcgtaa
      241 gctatatgta agtatggtgt cctaccatct gtaccagcct tacctgccac accatttgcg
      301 ccatcagatc cttttacaag tgtccaattg taatcagatg gagtattgct atcagcacta
      361 ttaaaatcaa catacatacc gatataagct ctatcagagg cgcttacaga aaaatcctta
      421 gttccatcag cgctattgct gtaagctatg tgagtgtatt gagtacggcc atctgcacca
      481 ttgcgaccag gtaatccttg ttcacctctt gcaccttgca agccatctaa accacgttgt
      541 cccggttctc ctttatctcc tttttctccc ttttctcctt ttactttagc ccacttgtat
      601 tttttagggt cggtgctatc gtttggttca aagtctgtat aaataccaat atagagttta
      661 ttgattgagc tatcaagact aaatccatct gttcctgttg cattattagc ccatgctgta
      721 tggacataag gagtacggcc atctcgccct ggagttccag gtgtaccaag ttttccatca
      781 gcaacattaa caagcgatat ctcatcaaca gcaacctctt tatttccaat gtaagctgca
      841 actgtcagag taactgtatc agttacattt gagcctctaa ctaagtaagt catccctgtt
      901 gttacttctc catcaagtgc ccatcgccaa gtaacaccaa caacgactgg ttttcctccc
      961 ttgtataagg ttggggttac tagactctgg ccgatctgat ttttaaagat aacaccattg
     1021 tccgttgaca atttgatagt atatggttta gcagcttcaa acaatctctc aaaggctgac
     1081 tggatatcag ctgatagttt gttttcaagt gccttgaaat tgtcaaatat tgtcttattt
     1141 ctcactggat ttgtgaaact gattttttga tcagtaaccc gtgcttgaat catcaataga
     1201 ggggcaaaac cgtcatcatg gactttaaca gtatctccaa tatcagcatc gacaaagcca
     1261 tcaacttcat aagtgatagc tggataacaa tactttttca atttgagata acctaaacgt
     1321 cttaactcgt ttggctcatc tgtttcaaaa tgaaaatctt ttcttgtcca ctggtcaagc
     1381 tcccctgttg aatgagtaaa ggttgaggga tatagttgca ttgaaatagg cgcatacagt
     1441 gcttgccctc tttgataaaa ttcaactatc cctttctcgt tctttacttc ccattcatcc
     1501 aatccctcaa tcgtcaaaac atcctcagtt gtatttgttt tttcttttgg atttggtttt
     1561 ttcaagactt ttgtttcaga cgttgatgct ccgccttttt tgctggttgt aacagtttgt
     1621 tctatggaac catcagaacg agtcgttgtg gtcgttgtga tccgtgtctt gtccgctaac
     1681 tttgtaactt tagtgtggac aatagttttg ctcttagttc catctgaggc tgtagagatt
     1741 gtggttttcg tcgttgaacc atctgcattt tttacagttt cgcttttgga gcccttatct
     1801 ccgctcggtt cttcttcaac cgttggcatt ttaccagtcg gtctgattgt attgaaaata
     1861 ccagtcttat ccacttttct tgtaatagag tggatgtttt ttccgtattt aacaatgaca
     1921 tcatttctta cacgtcccac cccttgatgg ttgtcatcgt tttcatgata aacattaaca
     1981 ctaaactttt tgatagtgct atcagcattt aactgtgtat caaattcaat ctcagcatca
     2041 aatcgtttgg ctaggcttaa tagacgggct agtttggttt cttgcccctc ccattccaga
     2101 gtacgcttat aatctgatat ttcattgata ccaatagaaa ggtgagtata atttaaaaga
     2161 tccatcgcct cacaatactc tttgaaagtc atcgctttgt tagatttata agggttcgca
     2221 agctcattga ttaactcaag attgagattt tcacaataac atttgattgt ctgctcattt
     2281 tcttcaacaa taatgatatt aaacacaaag cttttaccct tgtacttaaa tgagacaaat
     2341 gcatgctcat tcaaatgatg ataggcttta gcaagaggta aatcagactt tacagccttt
     2401 ttaaataccg taaactcaaa cgttgacgaa cctgttgcaa gacttcttgt ccaagtatca
     2461 tcgtaataat ttaacgtacc ttgtttttcg ttatcaataa atgctacctt ttgtaaattt
     2521 gcatcatgga ttgtcaaaag catcttatat ccacctttct tcaaattcga ttgttacagt
     2581 tggttttttc ttaacaaaac gtgaaaaata caactctagt tgagattttc ctggaggaat
     2641 tgctggccaa tgtgaaccgt ctacaacttc gcttacttta gatatcccgt caatatacac
     2701 actatcgtcc tcactgttga ttacaacatt tgaacctatt ggatagcgat taggaatatc
     2761 tctactcttt gtcacaaagt cttttctata catgaactca tcaacataca tatgtgatac
     2821 aagaggccag tctctgagtg ctccaagcgt gatatggatt tttgctgatt ttttgtcttt
     2881 tatctccgga ataataaagt cataatgaga gccatcaaaa aacacttgaa ctctatcatc
     2941 gtttcttttt aactctgacc agcccttttc cgcgctaaat ggatcaagtt tgcctacttg
     3001 agcccctgtc ccagtaaaat accaccattt gataaacttg tatccacctt tgccgtcagt
     3061 ggtgaaaaaa ctatactcac aatcaagtgt ctgatagcgt ttgtaagttt ccaccccata
     3121 caagaaattg ccgtctgtat ccgatacagt aacctttatg aaaccatatt gattagcgac
     3181 tgctgccata aaaacttgtc tccaaagcag atagtcattc aatgaaccaa cttctccact
     3241 actatcaaca ggaatagccc atgtcaaact ttgtgcatta tttcgatttt tttcaactgt
     3301 accacggttt gataattcga tatgattacg cccccacata cttgttgtac tcaaagtgcc
     3361 aacaagacgc tccttattat catttgttac agctactcct ttagtgccat tttgaaatcc
     3421 ttttagaata ttagtccctc tataatctat caatgtttca gagtctctgt atttttcagt
     3481 atcagcctct tcacgatttc ctaactcaaa cgccgctctg ttgttaacaa ctccaatata
     3541 tccattctct gagttgtgtt taattctaat aattggataa gctggctctg ttcctgtatt
     3601 tgttaaatta aatactatcc tatccggtgc gcttgtttca tttgtatcga tatcaaaatt
     3661 ttttaaagtc gtgctgtgag ccacgccatc aggaattatt atttttaact ctgagcgctg
     3721 gaaccatctt gtcaaatttt ctggagtaat ctcatctacc ggcaacccca tatagtattt
     3781 gtctggctca tcgccataag taatctttac tggctctaaa acgtttagaa tgcctgccaa
     3841 atcatgcttt aattgttcca tttcaattgc atttgtggtt ttgatgtcaa attttatgat
     3901 atgctctttt tctccaatct taacctgttg gatattcacg cccaataagg gagcgttatc
     3961 agttgatacg ctcctcttgt tcccgatagg gcggataata tctgttatac gaaagaattt
     4021 agacatatca actccgttga aagtcattat ctttgtcatg acaatacccc tttcatccta
     4081 ttatctcgtc ttagttgttc cgattgatat ttagcaaatt tatcgcctgt tctggcgact
     4141 aaagtaccat cgtttaagta catttcattt ggtcgtctaa cggccgtctc agctacatcc
     4201 agggcttttt cgagtagttc gctagacttg tccatagtaa ctttgatttt ttcagctatt
     4261 gtctgcttac tactttgttt aacagtcact tgagcaccta gtttcttgtt taagccaagt
     4321 gcaatttctg gtctagtatc aatcatcatg ctttctttta atcgcaacat tgatttttca
     4381 acaacccctg catctgcttc aataccaaca gcgatacctt gaggaatgaa acgtccgact
     4441 tcatcacgca ttgctctaga tggcgagtga atatctagtg cgctcttgat ggtcgctttt
     4501 accctttcag caattgaatt agctgttgcc ataacagaac cagagccact ccaaagccct
     4561 gcattaagac cagacatcgc catttcacca atgtacgtga aatcactctg cagactatca
     4621 aatggtttct taatttgatt ggctaaatta gtaacagatg atacaggttg attggtacct
     4681 ttatctaccc cctcagctaa accagtagtg ataaaaccac catactcatt gaaaacacga
     4741 gatggggaat taatatccat ttcgctcgta aaggattctt ttatatcatt agccatgttt
     4801 ttagaagctt cacttgcaat ttcagctcca gcttttatac catcaccaac accttcagga
     4861 atatttttcc ctttttcagg gaagtcagca gctgcaattt cctcttgtaa gcttgaaact
     4921 tgactttgta caataccctt gattttgtct gtgataccca aagcacccgt atccatacca
     4981 gcagttaagc cattcatagc tgactcacca ccttgagtaa agacttcgtt caatgttgcc
     5041 aattttttgt ctgatgcatt aacgagttct tgaacgtaca acccaccttg aggccccatc
     5101 gcttgcaatt tagctaaaat cccctcgttt accccacgtt cggccaatgt attgaggttt
     5161 gttgcccaat tattaaccgc ctcttggttt ttttggaggt tggcaatcat ttcatcgaca
     5221 ctaatagctg acttcatttg tatctgatca aacatgttcg ttgtggtttc aagcaactca
     5281 ttgtatttag agcgcatatc atcaaccgct ttttgttgag ctttagacat accttcgtat
     5341 gatataactt gtcgattaga tccattttcg gcagcagcag ccatcgcttc agatgccgcc
     5401 tgttgaactt gagacgtttt ttcgtactca gtttgcaatt ctgtctgagt attttttagc
     5461 tcagtttcct tgtcgttgag ttcttgcagt ctttctttac ggacactatc gctaacattg
     5521 gattcttcat tccatttttt gcgttgttca gctatctgct ttagctgttc gccaatttca
     5581 gcacgctttt gttcgatatc aagcaggttc ttctgggatg tctcccatgt tgattccgcc
     5641 tccatcgctg agatacgagc tttgatttgg tcattgttat gagacaaaga atcagtgttt
     5701 ttgtcataga ctagattcaa tccactaaca gaggcattta aagcatcaat ctttttcttg
     5761 agatttttct tgtctgctgc tgtcttattt gtcttttgtg ataactggac aatttcgtca
     5821 gccaattttt ggtaagattc tgtattacct tttacagact caagattttt ttgacgttct
     5881 tttgcgcttt gtttaacaga atccgttaat tgatccgtac tcttgactaa ctcctcttgt
     5941 tctgatttga ggcgtttggt ctcctcactc tcggcagtta gccattgcca caaccctacc
     6001 aatgccccaa cagcaagacc tacaccagca acaaccaaac caatcgggcc agttaaagcg
     6061 gtcagtgctg ctttaaatgc ggtagttgca gcagtcgcag caatagtagc agcagtctgt
     6121 aagctgatag agccagttag aaccccataa agcaaattgg atgctgtcaa agctccgtta
     6181 ttggccaagt tagcaaccat ttgagccttt gttactgagc cacaagtagc ttgggcagct
     6241 gtcattagat tgatgatctg aatcgctcct gtggctgttg ttttgaatgt ctgccaggaa
     6301 ttaattaagt tttttgttgc tgttatagct tcattagcgg cacgcatagc caccaaagca
     6361 gaaaccaaac taataataac tggtgtcaaa gatgagatta cagaagctcc agtacccaaa
     6421 atactaaaca aagtctgaaa aacaggtgtg ctagctttaa ttacgttgac aataacacca
     6481 aaagccgcat tgatgattac tttcaatgca tcgaagttct cagcaatcgt cttacctgtt
     6541 gctgcctttg ttaaatcgtc aagagccttg atagtattag ctacaccttt aacaaccgca
     6601 ttctttaagt tcccaaaaga tgtctggatc cctttactgt tagttttagc aagttctgca
     6661 aaaccaccca cgccaccatt caattcaacc aattttcttg aaaattggtt gaaagtgata
     6721 cgcccctctt ttaatgcaga atagaaatca ttctgagcag attggccagc aaaaccgaat
     6781 gattcagcag tcttttgcaa agcataaggc atggtttcct gtaacgtttt ccaactttgc
     6841 atgtcaacct tgccagctga taacatctga ctgaactgtt gtaaaccacg gcttgcatca
     6901 gcactagaag atccagaggc aagaaaggca ttattaagag caagtgttaa atctgttgat
     6961 ttgtttatat cgccagtaat cgatgtaagg cgttgagctg tgcctaccac ttcatttaaa
     7021 gtcgtaggca aaccctcaat acctgccgct agtttcttag ttgagcgcgt gacatcttct
     7081 gtactatgcc ccatagcttg catcactctt ggataacttt caagagtatc aaaacgttga
     7141 atcgctccgc ccaaggaatc tgttagaaga tctaccgctt tagatgccag tttaaaagca
     7201 gcaccaccaa tcgcaaactt ctttagagaa tcgctccctc tgtcaccttt ctgtgccgct
     7261 ttatctaact catcgtttag aaccttgact ttattaccat ccacatcgac aacgatggtc
     7321 acttttccat cagccattat cttctccctc ctttcctaaa ctatatttag cttgtaattt
     7381 acgcatttta ttcttatccc caccatattc tggtttccat gctcggattt ctataatctg
     7441 ttgcatgatt gtgttatctg gcaaagcgtt caaaagtgct ttaaattctg tccatgtcaa
     7501 ctcattttga actttcaaaa gattgatgcc ataagcttgt aaaaaactag cgtaaatgta
     7561 ttctgcatct tgttcaaaat caatcaattt ttcttgttct tcttcatctt ttgcctttgg
     7621 catgggattg cctagcaaat catactgaac agtttctttt tcgatttcta aaaaatgttc
     7681 ttttatgtaa atccaacagt ctacaacctc tttgatgtcg tataattctt ggccagttag
     7741 caaatggaca atcaactgtg cttgttctag acgcgtcatt tcatcctctt ttaggatttc
     7801 aaagacatct agaactttat taaaagacag gtctatgtcg tactctttat cagcaataga
     7861 aaaatttgtg attaaggcat catttaattt catagacata ttttttacct gctatttctt
     7921 tttgttcttt ttttgtttct tgttgttctt gattggagtg acttttccct tgtttaaata
     7981 gtgactagca cgctctttca ccaccgtttt gtgttgctca gcaacttctt ccaacttgtc
     8041 atgcaacatg attgcggtct gttctagagc gttatttagg gcgttataat ctggatatat
     8101 agaatataac ttgtcaaatg taccgtcgcc aaaaataaga tcatattgaa tctcaagctg
     8161 tttcttctcc aattcaatag ccccagcaac tacttcttta gttactccat cacgctcaat
     8221 tttgttattg atatttgcag ataccacatc taattcatat tggacaaggc gacgttttag
     8281 ttcttcttcc atgtcataaa agcgcattaa gctctcttga cttgtatcaa accatagctc
     8341 tacttctccg atttttactg gaaatcctgt acgttttagt tcaatctgaa tatctgtcat
     8401 gtctttactc cttttcctgt tgttaaaaag ggcaaggctc aatgcccgcc cttatcaaaa
     8461 gctattaccc aataccagtc tcttttggcg ttgagttgta agaaagctta catccaaacg
     8521 cctcatagtc agaggcagcg ccagaacctg ctttgatttc tgttgcagtt gcagctccca
     8581 cccattgttt cttcctgtca gaagaaacaa ccttgtgcca tagcttacgg tcatctcctg
     8641 tcttgtactt catcccagca ataagagcct gtgctttatc gtctggatcg taagtaccct
     8701 caaaggtata agcacctttt acgctgacca cggttgtttc ttcaactcca tcaccgtcat
     8761 agtatgcttg atcatctgtt ttctcgtctg tatcatctga tacgtctgag atccatttag
     8821 caagttccaa ccatgtatct tctgttgttg gttcagttcc tccattgtat ggagctacaa
     8881 aatggccacg tagggcgttt ttttgtcttg tcattgtttg ttcctctcta ttacgatttt
     8941 cgccacaatt tcaattgtgt aataataata gccttgctca tccttgcctt tcatggcagg
     9001 cctgctgact tccattccca tatattcata agaattattg tcacttggta aaactaagtc
     9061 tatctttgct agttctgagg tgactaacca aatagtgtca ttggctactg agttcttttt
     9121 tgcctttacg gcgatttcaa acggcaaaga aacttcttgt gtgccatcca tatactctct
     9181 atccactttc ccgcctggta tctgattgat aaccagatca tctttgtcat cctcaaagta
     9241 atcaaagcgt ggttcaactg gtaaatttaa agtcttgata tgctttaaaa gtacattttg
     9301 aaagtcattc tctcgcatca aagtcccatt cctttcacaa aagctctagc ccattcttca
     9361 gcatgtttac tagtagcaac ttgatcccat cgttttcctg tacctggagt ggtatatctc
     9421 ctaaaggtga caatgccgtt tgatccgtaa aattgcgctc tagcataaac tgttccatag
     9481 acaacagcat caccttgtcc aacaattcgg ccagaagctc tcaactctcc acccctcaag
     9541 gggatatatt gctcattgtc tagcaagatt ttgctagcga ctgcaatctt tcctcttgtc
     9601 atggattcgt tcgaaagttt ctgtttagct ttctgcaagt caactttaat ggcgatactc
     9661 attagatcac ctcaatttct tgactgaata tctcaccatc ataatagtta gtttgaaatc
     9721 cattaattgt ataatctcct atcccatcgt ttacttttgc acccatccaa ctgttatcaa
     9781 ctgtcacaaa agatagcgag ggatagaggt atataacccc ttgtttttgc cttgattttg
     9841 aatttcctgt accagttttt gagttacgat taccagatcc ccccactgat ctatcaaaac
     9901 gtacattttt aatagtcaac ggttctgaat atacttcatc cccataatcg tttttatcag
     9961 ctactttttt tatagttagg acatccttta acaaacgctt gtcaatccct tttaataacc
    10021 gcttatcgat cataggcaac tccaacaact aggctaaagc cggcttgtct caaagcattt
    10081 tcagcatcca tagacaaatt aaatcgctga cctgctaatg tgctttgtga ggtgctataa
    10141 gagattgatg tacggccaat agagacacta ttggctagct gtttgtcatc ggctgacata
    10201 ataccagagg catcgagata ggctatttgg aatgccatag caagctttac agcagatttg
    10261 cgataggcaa tttctttttc aaaatcaatg tctttctgat aaataccgtt agtgtatagg
    10321 tcaatcgcta tctttgcccg ttttgccaat ttttcaaagt ctgtaacttc atcaaaacct
    10381 aactcatcga actcctcttg tgtcaaataa gtcatgtgta acctccctta aaaataaagg
    10441 gtgttgccac cccttattta atcttcaaca gttgcctgag atgcatcatc tacagatggg
    10501 gcatcttctg gttcaagcgt tccatttttg tcaacaagtt ctaaaacatt tttcacatct
    10561 ggaaaagcat tttttagttt cttgttgact tctttagcat aatcttcatc aagttcaata
    10621 atgtcatcga caatcacatc catgttgagt tgctcaaaga aaagattttt tgttgctttg
    10681 taaagtgcca tgttctacct cctatacaat agttcctgta actttgtaaa ttgctttctt
    10741 attgtcatca agagtgtaag taccaccctt agcagcagct tgcaatttca caccatcaaa
    10801 gttttcagcc tcaattacac gggctgttga gataccaaca aacggaatga caataccgtt
    10861 tggtgagaag atagcgataa ctcctgtctc aaagtattgt gctggcgttt cttccaaggt
    10921 aaagccctta tattttggta gcccgttttc atcaagggag atagttgccc ctttggcgct
    10981 tgtaactgat gccatatcta cgatggcgtt gtaaaattca gaacgcaagt aaacagtaat
    11041 cggcgctgta acttcgttgt ttgtgtaaaa agccgacaac ttattgaata aagcttttac
    11101 tttgtcatct gtaaaatcag caagggcttc cgtcttagta gcgttgtcag acaagtattt
    11161 accaattcgc ttgttcactg ttcgagtttg tgcctcggat tgcaacttca agcggtcggc
    11221 aacagcagcg ttaagatcat tgtttactgt gtaacggtca agcccctcat ggattgtaag
    11281 ggtatagtca tagttgacat ctgtattttc atatttaact tctgtcaaac caccaaagcg
    11341 tgactgagcc cctgagttat caccaaaacc accatcattt tcaccggttt tgtactcacc
    11401 gattacaact ggtgtgttgt ttgttttaac tgagaaagcc gtggagtttt cttgtacccc
    11461 atccaaaatc tgaataggtg ctagagcgtt tgaaaatgct gcccgcactc caaaaactgt
    11521 ctcaagaatg cccgcatatt gtttctcata gcggcgcact gcgttgtttt gattacttgg
    11581 catttgtaat ctcctttctg ttatttgcca tacccgtcaa taatcgcttg gaacggatca
    11641 acatcacttg taccctctcc tgccggatta ccttgaggta aaatattggg gctaggctta
    11701 ctttcttcag ctttgaacag atatggatca ctttctttta aaccgttgat tacttcatca
    11761 atctgaggtt tcccgttgtc gtctaactgg atagcatcaa catcaatgaa tttcatcaat
    11821 ttgtctggat tgaaagcatt tgtatctttc agagctagac tgatagcact aacctttttt
    11881 gtctgtgcaa gttcagctgc agcttcgttt ttatacttgt catattcagc ttgcaattta
    11941 tcaatcgcat ctttttgttc agcgctgata ttctcaagtg atttcaagtg ttcaacttgc
    12001 tcctctgctt tttgcaactg tgatttgaga ctatctcgct cttgtttgat agtttctaag
    12061 gctgatttgt cctcattcag ctcttttcct cgcaaagcaa agactgactt agcctgttct
    12121 tctgtcaacc caagattgag tagttcttca gttgtaaatg ccatttgtac cctcctagtt
    12181 cttttttagg tggataactc ccacctaaag caaaatatta tttactctct caatatacct
    12241 ttgatggata gggatttttt acggttttaa acacaaaaaa ggacttgtga aacacaaatc
    12301 ctttatgaaa tatataattt ctctcgtctg taatctcttg ttaagaaatc atgctgattt
    12361 atcaagttgc ggatcttagt ttgataccct ctaactttca aacgctcagc ttgtatcatc
    12421 ttgtcatctt gcaaggtatg agcgtaatgc aaccgctctt tatgtgtctt gataagtctc
    12481 tcaaggcctc tttgacctgc ttcaatgcgt gcattttctt cagcttgttc tggtgttaga
    12541 ttcttcagat agtctggtaa gttcggtaac tcatgaactc caacaataaa cggtgtcaga
    12601 taatgaccac aatggattcc taaacatcct gctgctgttc catacccata atccaataat
    12661 gaatagatag ttatcccatc tatctcccta ccagcccctt ttgtaactat ctgcccttgt
    12721 aacggactac aagctggtct agccattgct ttcatcgaat agtaaaaagt atctactcct
    12781 aactcctcag caggtctagt acgcatttcg ttataaactt tgtatgttgt gctcttgata
    12841 atagccctcg catagctatc agctttccaa tgcctcccac ctttatcgac aaagcccgta
    12901 aaagcgttct tctgccattt catgatggta tcatgcaaag caacatcgct tgttttagtt
    12961 cctgcaacta cctgtgcgac tgtctcctcc acaatcgatt tataagctac ttgcaagctc
    13021 ttaggcaatg ttgtattgat aaggtttaaa tcactaactg cttgcctcga ataagcctct
    13081 aagctgtccg ttacgccatt tgaaatctct ccctcaggta ttttattcaa atcttcttca
    13141 agttgctgtt tagtgtcctt atagactttc aaaccttcat tctcaattac atcacgcaac
    13201 aatctttcag caattcctgt acgctctgaa ataagcttta gattctgttc attgagcatg
    13261 tgcatatcat ttagtttctc taactgccag atataagggt ttctcattaa atcaatagac
    13321 ccacgctctt ttaagcgttt tatcatacgg tcaaagatat caatctgtaa tttttcgtaa
    13381 atatccccaa cgccttgcat ttgcaaagga aattgttggt cgttaaacgt gagctgtttt
    13441 ctcttttttt tcattcaaaa gcctcactaa ctacctcata ggttgcattg aaaatatctg
    13501 gcttgcacgg ataaaactca tcctgcactc ccttaataat ataatctcct ttttgagcta
    13561 ccatatctcc ctcaagcgtt gaaattacaa tacttaaatc agagcacaag gtattttgtc
    13621 caataaactc tctgacctct tcatagtttg acccaataaa tctaattgcc tcaattacaa
    13681 ctggtttctt cttatacttc gccatcttct tcctcctcgt tttggtcatg cataccataa
    13741 atagcaagtt cggcatcatt cataggtagc aactcactat tgatagcatt gagttctttt
    13801 tctgcctcaa caccagaaat atttaatgtc ttaccaattg cccgtttttt ggttgagaat
    13861 cctgcggcta ccattttagc ccaataatca agttctgcat gcctatcagt aaatacacca
    13921 tcatccaaat taactgaaat atcatcaagt tctggaattt ctccgctata aacccctacc
    13981 gccttaccga gctcacacat tgaaacacaa agctccttga tagattgttc aacaagtgcg
    14041 acaatactac ttcgcatctg ataagtgtct gagttctcgc tgacaatttc tgttgcagtt
    14101 ttcattcctt gaccatcgaa tgtaaacatg ccacttgata caccaatctg catttcaaag
    14161 agtttcaatc cctctgaaat cgccaaaata taatcatttg ctcgaattgg tgaggtaagg
    14221 tctgtaatgc ccccggcatc catactagag ccgccaattt gcatataaac attctgctca
    14281 acatcaaacc gtggtctaaa atctattgtt ccatctggac gttgatattg tctttgtgtt
    14341 agatgttcgg gcacaataac tcgtctttgt cccatcctca cttcccacat aaattcatcg
    14401 taagaacgat tgatgaagtc aatagtcgtc tttgcgttat caaagataga caatccaaga
    14461 gggctgttga tgtctttgtt attcatacct ggagttttta gataagtaaa tagaggtctt
    14521 gataggtttt caaagactgt tacaggctct aaatttttgt acttgtctag ttcactcaag
    14581 ttcacacgtt gacctaacac atcattcaca tctgacctat aaagttcatt tgtaatacga
    14641 taatactttt tatcgtttgt gctacctgtt tcttgtccgt ctgctgttac ccattcgtga
    14701 aattcaacaa gggtatagta aacgttctta cgcccctcag atttgatagt cttagtaagg
    14761 attgcagcac ttgaaacatc ttgtgtgttg ctttctagtg gaaagaacac aggcgcttga
    14821 ataaatgcca ctctgacctt atccccgtca atataagggc gcatagctag gccaccaagt
    14881 gccaaacagc tttctagata ccgctcaaaa ttcttattga atcggtcgtt agttagcatg
    14941 tcatccaaaa atttctgtaa aatttcgttt tttgttgtga tagttgcctg ttcattgtaa
    15001 actaagctag caatcttctt cgatgctgtt cttgcaattg gcaagtgatt cattggacgg
    15061 gatttaatat ctccatccgt attcttgtac tgaacatcat cccattttga ttgatagtag
    15121 actagatttc tcttaatccg gtcatactcc tcttgagtca ctgcaatttt tggatgttcc
    15181 aaaatactat taagatttga tgtctgcatg taatacctcc ctcgactaaa aaagtctttt
    15241 actttttgaa ataggctcat gatcgtcctc ctctaaacgt taccaacacg caaaccgagc
    15301 aattttgcat tgtctaacac aaaatactgt gttgtgtcgc atgtatggtc atcttctttg
    15361 ataacgctag gattatcaga tttgatagtc ttttcatccc aacgatacat cttgtgttct
    15421 tcaataaata tcttgttgtt ttcggtgttg agatagtaaa agcgaccttg agcaagcaaa
    15481 gattgaaaac tgtcaatcat agtcactttt ctaagtttag cgactggatg ccatttcaaa
    15541 ccaaagtcaa gaaacatctg gtttcttaac gctccctcag cactatctat tgtgtattgc
    15601 aaggcttgta ctctgtactt ctcaataact gatcgcatat aagcatatat ctctttagat
    15661 aactgactag gcgctttctt taccacttgt ccagctggtg aataatacca agtatctagt
    15721 aatataacct tacctttagc tgttattcca aaagcgcaac aagcggttgc tgactgttga
    15781 tgtccgccat ctagcgcaaa tgatatgcca atcagcttat catcgctagg caaagcatca
    15841 atagcatgaa acatactcat gttatacacg ttgttaccta atcccactgc ctcacctaga
    15901 tataagtatc tgtaataatc gtagtcattc tctttgatac gctctatatc ttctagcatc
    15961 tgctcagtaa cgaatccgag ttcatcatca agataggtgc ttgagtgagc taaatagttc
    16021 ttattcgttt tgatactctc aaaccattca ttgatccaac tatatggatt tctaggtgga
    16081 ttgtaactcc aaaagaattg tacaaacttg gcgcgtgggt gtttctgcct catgaacgtc
    16141 acgtttgatt ggtcaaagtc ctcttggtca ttaaattcag cagcctcttc ataccaaacc
    16201 gctatgatat ttccaatgtc gtttgatttg agtttttgaa agtcatcttg tccgtaaaag
    16261 taaaatgttg agccggtcgt tttgtgtacg attttaaacg ggctaactgt ttttgtgaac
    16321 tgctcagcta taccaaaaag gttcaatgcc caccaaactt tattgaaaac actgtctcta
    16381 atagtattgg ccaccttacg gataacaacg atattggccg cctctccagc gataatatac
    16441 cttatcatca tatacgctag tttaagtaca ataaccgatg atttaaaaga gttacgccca
    16501 cctttcaaaa cattataagg taagctagaa atccaaacag atttgaaatg agggttgatg
    16561 ttcttctgga cattaaaggt catccgttgc ccccctcaca tcttcagccc atgcatccac
    16621 tatctcgata gtttcacttg agcctttctc agcttcagca cgctctctat tttcatattt
    16681 gagtgcttta atacgctctt tctgttcttg tatatcgtat ttatctttag tatttgtcag
    16741 cttgattatg ttctcagtcg ctttctgatt gccttttaca gcttgctgaa aggttgcaaa
    16801 ggctagcaaa gcctcgttat tgccagccat acccatctcc tcaagttgtt tcttgatttt
    16861 actatccgtc acatccaaag ataagagggt ttcaaatgct tttttgagat cagctttttt
    16921 tcttcttgct atgccagatg ctttacctcc ttttgagcta atagctcttg cttcatcttt
    16981 ggttcgttct gtaactggtt ttaaattttt agttccatct ctaggcaatt tccaccctcc
    17041 tttcaaacaa aaaaatcaca agcattttat acttatgatt tcattgtata tgttaaaaaa
    17101 ggggatgttt tacgctattc ctaataactt ttcgattttg ttaatcaagt ctctatattt
    17161 tgagttgtca ttttcgttgt tgacaagttt aattttgctc ctctaccacc cataccttag
    17221 cctcttttct tttactcgta tgagtaagtg tacccgtatt tcttagcgtt tttcttgagc
    17281 cataggtcag ctcctttatt gtaatctttt gtagtaaaac gtgacttgct cacagcttta
    17341 tcaaagcctt tagcatcaaa gttagcccct tttgtaattc gatacgcttt agagctattc
    17401 gttgcaacta gtgtattcat accttttaat gctgcaaagc tatgtaaatc tgtacttgag
    17461 aaattgctgc cattcggatg gttatgtatt gctgtaaatc caccagagat aggcaaaatt
    17521 tgtacgctgt ttttcccacc gtgtacataa ttatgagcaa agccttgaga gtcaactgct
    17581 gtactgtatt ctgtgctaga gccaccgtgt tttttaataa atccctgaat agctccctca
    17641 acacttgaaa agcgcccttg attgtttaaa gatgctggat gtaaggcttt tgagctccca
    17701 ctatctcttg caccaccagc acctctaaaa cccggatact taccgtcttt ccctttctca
    17761 aaatttgcac cacgtccacc gcctagagtg aaattgattt tatttacttt ttccatcaaa
    17821 tataggtcat tttctgcctc ctcgatagat tggtattgtt tgcttgtttc tgtttcttta
    17881 ttgtaaagct caagatcttc aaataaaatc tctttaccta gatcaatact tgaaacatgt
    17941 ttaaaaatat cttttagttt agttagtttt tgtgccactt tctttcatcc tttccgttgt
    18001 tgcattttca aaatatacaa cctctatatc tttataatcg tattccactt ttccgccata
    18061 tactacaatt ctttttggag ccaaccgttt tatcatctca gtaactccat ttttccatac
    18121 ctcaaactgc tctttgtttt gctttacgcc tattgtactg attgctagcg ttgagttttt
    18181 aggcaagccg tcaaaacaaa aatcaaagct ttcctcacta gcccacgata cagtagggat
    18241 aactgtaagg ccgtaatctt gcataatctg acctatcagc cttgacctgt aaatgttcca
    18301 tacttgcata gcgataggca tatcaagata taagctaaaa tccggagcta aggcgctatc
    18361 aaattctagc agcttttcaa tgtaaaagtc tggtctttgc catattcttt caaattgata
    18421 atcatctagg aaaaaatgca cgcatgagct gtaatctggt ttatttaaaa cataattaaa
    18481 gccttgaaaa tctttaggaa tatgatccac gccctcgatt ttaggcatgt tataaaaacc
    18541 ctcaaccctt gtatcgtcat aatgaaaaag attgtactga tttatagttg tgtctctgtg
    18601 aaaatcctca gcatcttcct cctcgttttc agtttcctct tgctgctcct cctcgttacc
    18661 aaagttgaac cctgtaactg ataactcaaa accaaactga gccatatcta ttgtttcaaa
    18721 ttgagaaagc tcaatattta ataattctga gtcccacgtt gaatactcag caactcgatt
    18781 atctgctagt ctataagctt ttatctgctc atctgtgagg tttacagcgt gagcgatagg
    18841 tattgtgtct atacctaaag aaagagcagc ctttagccta gtatgtcctg taataatgat
    18901 gttattatca tctactaaga taggttgctg aaaaccaaaa gcttttatgg atgcagcaac
    18961 tttctctgtt gcctctccgt cattatgcct agcgtttttg tgatatggtt taatggattt
    19021 tatatctaca tattcaatct gtaacatctc catatctctc ctttcgaaaa agcttatata
    19081 tcttgattat agatacataa gctttggatt ttttacggtt atttatctaa gatggcgttt
    19141 tctagtaatt ctgtgtaagt cgcacgaaaa taatcgttaa accacgcatt aagtaataca
    19201 taggcttgag tcggactata aaatagtatt ttttgacaag ctccaatgac attcatgttt
    19261 tcgtaaacat aaacctcttt tatcgcccgc aaatatttag gatcagaccc atctataaaa
    19321 tcttcagttg atttttttaa gttagttaaa aacttagctt caagcctatc agttttgata
    19381 tgagaaacta taattttttg ctccagaatt gttctcttcg gatttttctt atctctcaaa
    19441 aaataccact ttagccaatt gatttccctg cgatggataa ctgacaagcg ctctattttt
    19501 ttcttcgtca tcttccttct ttctccatct cctcaatcag ccagtcaaga ttctttctgg
    19561 ctttctttag gtcttcaagg ccgtttttct tctgatgccg tagtatgtac ttcaagctgt
    19621 tacccatata gaaccctttc agctgttctg gtgtcatgaa gtttcttaga gtatcgatag
    19681 attccattcc aaatctacct tggtagtggc ttggtttgtt tatgttgtca attatttctg
    19741 ggttcattcc ttatcctcca aaagttctgg gttttcgtag atgttgccga tgatttcctc
    19801 atcttcagtc cacacatacc cacttagcaa tccctttaga tatacagcag gcattccgcc
    19861 tatgtatgtg ccaccatatt ctttttctaa atacacttcg tggggacatc ctttagtaca
    19921 ttttataata tctccgacaa agacctcttt ctcgttcttg tctttgagtc ctgttgattg
    19981 catgagttcg atatcgtcaa aatcataaca atagatatct ctttcaactg ctagaccact
    20041 ctcgaaatag acttgttgtg tcactatttt tttgttttcg tagtcaatag caagaatgtc
    20101 atctgaaaaa accatacgtt ttcctatttt tacccacact ctaaatttcg gtatcatgct
    20161 aacactcctt aaataaacaa actagctaac catatcaaaa atgcacatgt aatgattttt
    20221 gaaatactgc tctttaccgc atacgaataa tcctcttcag attctttttt gctagataac
    20281 acaggccaga tgaaagatag tagtgcatcc atccctaatg cttgccagac tgtaatttta
    20341 ccaactggaa caattgttgt gataatctca ttccatccat actgaactac aaatggcgat
    20401 acaacgatta caaataccgc cccaataatg attcctagtc ttttcatttt ataaatcctc
    20461 ctctttgacg attgtaaatt cacggtcatt tatatttaaa ggtagaacta ccccttctaa
    20521 aacttgctta cctaaaatca attgtatctc taaaatattt tgctcatctt ccatcactcc
    20581 acctcctcaa aataactatg aaatttactt aaattgacaa tagcgacctc ttcaacagaa
    20641 tgctttccga tgtcaaagtc tggatcattc ttcccaaact ctttttctat agctttttca
    20701 gccagaaaag gcaaatcgaa tatacttgcc ccatttctta aagcgagcgc ttgaccgtat
    20761 ttgttcacta ttcgataccc tatatcaaac ggtctgattt cccttgggac ttttatgcat
    20821 ttactttgat tcttcattcc ttcttcaagt gtttgtgtca tcactccacc tcctcaataa
    20881 tatccaatac tttcaaaagt ttatctactg aattttgagt gataaaaata tcgtgttctc
    20941 ctaaattgta aggtgttctt aaaaacaaga tattagggcc tagacagatg cgactaatat
    21001 catctatgtt gataagctca tcttcagtat ttcctctata acaagattgt attttaacaa
    21061 attttgtcat ttattccacc tcctcaatct caattccttc acaatcaaac acccagccga
    21121 agtttgcgtc ttctagttct ttttgagtac ctttataatt cctagctgtt atatcttgac
    21181 taaaataaag agtactccct gattgcgatt tgaccaaagg ctgcctattt tttaaagtca
    21241 ccaaataccg cttctcttcc tcgacctcgt agccgaattg gttcatgtaa actgcaataa
    21301 ctacctgagc catgcttggc gaatagccaa cccaatcatc aaactcctta gattttggca
    21361 accaatcctt agtagctccc aaatcatagt ctgtaggctt ttcatcagcg aagatgcatt
    21421 ccatcgctcc cataaacgtc ataccatctt ctgccatttc ccaaaaatag tccgcccggt
    21481 ctttcaccac ttgtggtaaa tcttgcttgg gaggttgcgg cttcccgtct tctaccgtcc
    21541 agttgtatac ttcattaact ttttgcttta actcttccat catcttccaa ctcctcaaaa
    21601 taactcagat tctctaaagg tcaaaaaacg attagatctg gttatcttct acaaccttaa
    21661 attgtacact ttttataact ttaggattta atagaatacc tctatcttcc cctaaaacaa
    21721 ccacatgccc attattcatt tgagatatga ttgcatctct aatttttcct agtttagtat
    21781 catcttggta aaagccatgc gcttcaaaat tatcgaattt tatattaact tcaatcactt
    21841 taaacctcct ctatatcaaa ctctaatcta taatgccctt tttcctcgct taatccacca
    21901 taaacaaagg ataacttttt gataacctta tgattatcat ctgtccaaat acctgcatca
    21961 gtcatgccat caatgatagc cttgactgtt ggatataaat taggtgggtc aagttttgac
    22021 ttagtagggc tgtaaattgt aactgtaacc tcacaagggt tggaggggct aaaagcagcc
    22081 ctccctttat ccttgttcat cgatgtatgc caataagcaa aagctctaat gcgtttagta
    22141 actttagcct tatctgtttg atgttgtctg tcattactat tgataaccat gtttagagat
    22201 tttagcttag tattccgagg caaagaaaac tcaaatttca ttttgattac cttaaaactc
    22261 aatgttttca atttctgcca tgtaatttgt tggcgaattc tttcaagttc tctacgatag
    22321 tttcagctga taccgtgttt ttagtttctt tagtcattgt ttttcccctt tcttatgcta
    22381 atactgtgat atgtttttgg tctgctagtt gctcttttag atatgctgca atatttccta
    22441 ctgcatcagc tacccaacgc ttaccatctg cctcaaataa agccatattg gcttgcttat
    22501 caatcctaaa gacaaatagg cttgccggtt gctcaacctc gctaaatgta cgatatgggc
    22561 gcaatgtaac tggattaggt gctttgcctt tagcaaggct tgccacccct gttttaactg
    22621 ttgctacttg agatactcca ttatcttcaa tttcagcccc attctcaatt ttcaatgcgc
    22681 tagcaaattc tagcaatgtg ggttagatct aacccaataa gttttttatc catattgtcc
    22741 tcctgcttta aattaagcta atttgaaata gctccatcaa atactttcat ctaaacacct
    22801 cccctccatc tgagtaccat ttgtttttaa gtacatgacg tgcaatctca cattgcactt
    22861 gtggtttctg ataataatcc acttttgcct tgtgcttttt aatagcttgc atagcgtgaa
    22921 ttgtaacaat cgctgcccat gtgatagaca tcaaagttgt aagtaccata acgatttcaa
    22981 tttttgtcat tttctgtttc cttttcaaat tggtttaaat aagaatttca taacttaact
    23041 agaatatccc ctttcgctaa aacggcaaat catcatcgct gatatccaat gggtttgtcg
    23101 gtctaccaaa tggattgtta tcacgggtga aatcaggaac tggatttgtt gtgttcccct
    23161 caaagaaact accttgttgc ccgtaactat ttccattttg gaaattgttc cctgtgttat
    23221 ttccgttttg gaaagaactg ccctggttgc tgtaaccctg ttgctgataa ccgccatgat
    23281 ggtcttgatg accttgatta ttttgctgac tgttacgact ttccaacagt tgaaaattac
    23341 tggcaacaac ttctgtgaca taaacacgtt gaccttgctg gttatcatag ctacgtgttt
    23401 gaattactcc tgtaactccg ataagagagc cttttttagc ccaattagca agattttcag
    23461 ctaactgtct ccagataacg caattgataa aatcagcctc acgctctcca gcctcgttct
    23521 taaatggacg gtttacagca agagtaaacg tagcaaccgc aatattagat tgcgtgtatc
    23581 tcagttcggc atctcttgta agtcgcccta ctaaaacaac gttatttatc attttgcacc
    23641 tcctctactt ctgatacctt gatttcattt gaaccaaact ttaataagtc ggtatatcgt
    23701 ttcacaaact caatagcagc cataaatgaa ttttctgcat tgatttctga ccccaaatca
    23761 agatctgcaa ttttaccgct gacataaaaa catctcatag gtctgactcc ttattctact
    23821 taatcctcca aagtttcaaa accgataaag ttatcctcaa aatattcttg tgtattttcc
    23881 cactgttcta aaccaccgtg caattcaaga cgtactaatt tgaccaaagg ctcgctaggc
    23941 tcaaattttg ccacctctcg cgcattgttt tgaggttctg gtgtaattgt accctgttcc
    24001 aaaatctcgc ctgtttcggc atcgtaagcc ttgatattcg cattagcatt tttcttggcc
    24061 gattgagcaa tttcttcaag tcgttcagct tttgcttttt cttggatttc tttctgctcc
    24121 ttgcgtgcaa tctcagcatc tcgatcagtt ttcatcatct tgagaatatc aacaagactc
    24181 ttaccatctt caagatgtct gatatagcta tcagctggca aatcgtactc ttgagcttgc
    24241 tcttggatag cttgcttgtt agccttgtat tcttccaggg catcaaattc tgaaagtact
    24301 aagccatcca tttcatcaag tgttgtcttt ttcagctcat acttgcctgt tttaaaatat
    24361 ttcttgaggc tgtactcatc gtatttgtca gcgaatgtgg atttttcaat ccctgcgacc
    24421 atacacttat cctcaaatgt agcacgcacg acatccacgc gcatcaatcg ttcatgttca
    24481 tcaatcgcat taagtcctgc tgacatagca tctgttacgg cctcaatagg cttgatgact
    24541 ttttctttga cccacttatc aaagtctttt gccggctcat tgatttgtcg gttaaaatct
    24601 ttgcgttgag tgtctaagcc cccaatcagc ttattaaagc gggttcgctc ttcataaact
    24661 tctttgtaat tatcaacagt aacctcgcga ccgctatact gtgcaatggc tgtggctact
    24721 tgtgcctcga tcgcctcacg gtcaacatta attactgcag gttgaaaatc caccttgatt
    24781 tctgtcaagc tattagttac atcttttacc atgtttaatt acctctcttt gcttttgcct
    24841 ttgctagttg ttcagttaaa tagtttttca atacctcgta gtcaccaact tgtactctat
    24901 gaaaatcttg taaacctttt aatttttcag atagtacata gttagcaagc gtatcgaacg
    24961 gcatcccttt aatttttgca atatcattta taaggtcgtt aatttcttga tactgaatgt
    25021 tgtcaatata ccttacttga ttttgtcctt gggcttgctg gttgtttggt ttctgttgct
    25081 gattattctg tccttgctct tggctttctt ctactggata ctcatcaaca tcctcacctc
    25141 caatggcaaa taaaccttgt aaagcatatt ttctagcata agaaccaacc gcacctgtcc
    25201 attgtggatc ttgcatctgt ttcacatccc ctttttgtgt gtgaaaaatt ggtacatctt
    25261 cttctctagc ccatccaata gctttttcaa tcgtgccatc actttctctt ttagcaacag
    25321 ctaccgcttt ataatacagt ttgtcacctt tttgaatgat gtcatcttct ggaaatgata
    25381 cactccaacc gctatccaaa gacttaaatt tattatttat gtcctctgcg gttctaaacg
    25441 gatatttcac tccctgtttc gtttgttttt cgatttgcat ttttcgctgt aattctgcaa
    25501 atgttaaatc agccatatta tctatcctcc aagtctacta aaaggcacat cccatgaata
    25561 gttagtaaag ttttcgttta caatattctt gatgatttca ccttttgaaa tttcaatttc
    25621 ctgtgtaaat tccataccca tttcaaaagt gaaaatttta atatcaacat caaacttact
    25681 agaaatttct gtgtaattgt cagctgatgc tgcccatgct tgtttgaaat cttcaagttc
    25741 gataatcaca aaatcatcat ccaaccaaat ttcaatatct ttactagaaa taaacgcacg
    25801 tcttgtaccg tttatataaa aataatcata ctcgttttta aatattagta gagtgccatc
    25861 gtattcttct tcaagcgttg cgcctttatt tcctaatagc atttctttta aagctgatgc
    25921 aacgttttcg cgtctgcctc ttaatttaag agtcccctct gcccaatttg gcatatttct
    25981 ttcctccttt aaaaactctg taattccctt attatctata agtatgagtt tgttatttgt
    26041 tagtagttat tattctgcta tcgtgtcatc ttaacggttt tagccatttc tttcttccat
    26101 gattgactgc ctcgatattg cagataagca tcaaaacctt tgattgtgac aagctgacca
    26161 tcatttctga ggtgcttttg ttgactaggc aattttttca tttctcgcct catgtctccc
    26221 gcttgtcttt tagtgcatcc gaaaatgtga ctaagctcct catcgttacc agaaatcttc
    26281 tcgatgatca catctttaat tctcacgatt tgaactgctt ccatttttgc ccctttcgtg
    26341 atataatcac tctgaataat tttattgagc gcctgattgc cgtcaggtgc ttttttgttt
    26401 agtcatatac agttactgta tagactgtct ttcttgctcc atcgctagaa tgtacggtcg
    26461 acttctctac cgttatatct gtcgtatcgt tagccatttt gaaaaacaaa tacaacaaac
    26521 attctcgtaa aatttttaat tttaaaggaa ctgatagaaa tcgtttaatt tccagttcga
    26581 tttgactagg attatttgat aatactagtt cgttcattct ttcctccttt ctgtttctaa
    26641 tccccttttc tgctataatg aaaccagaaa ggagggttaa aaatgtcatt tgataaaaat
    26701 atagctgata aaatcctaga gtttgctaag ctggaacaga ctgtcccagt aggcacttct
    26761 catgatttcc gttctgaaga gtttgatcaa gatgatttta gagataccgc taagaaacta
    26821 atctcaactg gtcaaatttc aggacatctt gaggaagatt tctcaggatt ctatatcgct
    26881 ttcagattgt aatttctgaa tttcagcaat cactgtcgca tcaatttcca ttacatctgg
    26941 aatcgctgtg atagtgattt ttggtttctt atccgcaggc atttctagtt taaaatcaat
    27001 tacccctcgg ccaagctccc aatcattgat ttttactgaa tatcctgaag aattaagaca
    27061 ttgaccctca gtaggttctt gcttgggttt aatacttagt tttaattgct tcatgagtac
    27121 tcctttccca tttttgcaaa gtcctaaatt tgaaatttcc tctcttttat ttatttagag
    27181 tagtagtact tgttgttagt tagtatttat tgttatttaa tacttgttgt taattagtat
    27241 ttattagtgc ccaaaatctg acatctcact ttctgacatc tcactttctg acatctcact
    27301 ttttggaatg tcagaattat aattcataga cgcccttttg atagataggt tcaatctctg
    27361 tttcataata tcgaattgga aatcagatat ttttacatct gaaaagaatc tgaatatatg
    27421 actccctcca tttccaggag gtttttttct gatttttcgt aaatatccag cctcttcaaa
    27481 gattttgaaa tacttatcga ttgtctttcg gttaacacct tttcttttag ctatttcatc
    27541 tggatagact tgccagttag ggtggttagc taggacaacc atcataatac caacagctgt
    27601 aaagtccagt tttgggtcat tgataaaact attactaaca gcagtataat tttcagtcgc
    27661 attcttgaaa gataaactga caatctaaat ctttaaagtc tgtcataact cctcctttta
    27721 aatttgctat aattgactta tcttacatga aaggagaata agtcatgatt acttgtcaca
    27781 tcatgattga tggtcgtgtt gaacctctac caatgacatt gcctgctgtt cctactatcg
    27841 gttctgtcat tgctaagtca gcagaccata aatctgagca ttacttggtg aaatgtgttg
    27901 agtatgtcaa cggacatgag agtgtcaatt tacatgttca accatttcct aaccaaatca
    27961 gtgctgtcaa cgctgttgat ggtttcagga atagcagata actctactat cttgacccaa
    28021 tagctatcta gcactttctt atcaacatag accgcttgct cacataagcc gatatgctca
    28081 ttaatgacta tcgccctacg gacaagtagg tctttttctg tttcagctcc aatatatcct
    28141 gcaagctccc cagaaatttc tagatattta ccaattaggc tattttcttg tgccatagcg
    28201 cctcctttct cttcgcttat tttcaatcac tttcgcccat ttctaacctg tcaggtattc
    28261 ctgattaagg aacttattga taaaatactg ttgtcctttg cctgtgacct ttggtgtctt
    28321 gttcacagtg atatgtccat ctgcgtgttg cacgtttgtt tccttgattt caaagagttt
    28381 caagtccatg ctacgttggg ttggcatgtt ccaatctgaa cctttgcgct taatcaggta
    28441 gccattttcg cgcatccaag aaaagaggcg attggcaccg attttgtagc cgttttggct
    28501 aatgagcttg gcaagttcgc caaccaagat agatgtatgg cttgcactta ctgcgtctgc
    28561 aaagaggact ttgggtttgt ccgcttcaat ctgagcctcc agcttgtgga ctttctgatc
    28621 agccatgagc aatgctcttg ccataatctt ctcagggcta ttaaagtctt tttctacttg
    28681 gataaagtat tgtcggactt gcttacctct ctccgtccgc tggatcatag caatttcctt
    28741 ggccatgtct agcttgatga tgtggtcagt agcttgtcgc cctcctgtac tttttcccaa
    28801 atttgggaga aagtcctgac cttctgtaaa tccgtattcc ttcatacggt caaaccatgt
    28861 tgtatatctt gaattaacac ccagcgactc atgtagttgt cttcctgaca ctactggctc
    28921 ctgattgtca ttcagggtta cgttgatgag ttcgttcatg ttattcctcc agcaattgtt
    28981 caagacgaac atttaaataa tttgcaattg aatttagagt agtggcagat ggcgaactgt
    29041 tgttccattt gctgattgcc ccgttaccta aatcaagatc tttttcgatt ctataaatcg
    29101 aaatcccctt ctctgaagca atttctttta ttttgtcata aatcacttcc ggcacctcct
    29161 tttgatagaa aattttataa gaaaataagc attattcatt gacaaataat agaaaatagt
    29221 ctattataag ggtataaaaa atacagctat atcataaaaa cagatataac gaaaatcttg
    29281 gcggattatt ctatttgtat ttatgtcagc tggtcaacta gcttacaaaa taagtataac
    29341 ggaaaatttt ctatctgtca atcattttag tagaaaattt tacattattt tgtaaagcct
    29401 tatttttgga ggtttttaca catgactatt ttagatagaa tacgctcgtt agccaatgat
    29461 agaaaggtta ctcttgccga attggaaagg aatttaaatt ttagtaatgg cagtctcaga
    29521 aaatgggaaa cttcaactcc tagcggcgat aaaattgaaa aaatcgctga ctacttcaac
    29581 gtatctacag actacttact tggtcgcaca gataatccta ccatcgctaa taaaaaagaa
    29641 caattctttt tcgaaggcaa agaagtcgat gttgaggaac ttgcctctac cgctatgcgc
    29701 ttcaatggta aaccactaac tgaagaagat aaaaaagcaa ttcaaaacat aatagagatt
    29761 tatctcagaa agcaataata ataaaaggtt ggattgttta tgactgaaaa agaattttct
    29821 caaaatctag gtatagatat agagattttt gaagatggtc tatttccaga tgaagccttt
    29881 tacatcccag ccctcaaaac tatgtttttg agtgatgcta tatctgatga aaaaagggta
    29941 caagtcgctt tacatgagat aggccataga aaccacgcgc cagatactta tcagcttttt
    30001 agggaaaagt gtgagcttga ggctaatagg aatatgatcc atcaccttat gaaagctgag
    30061 ttggatatag ccgaagatgc cactacattt aattacctgg tatttatgga aaagtataat
    30121 ttaaaaacca ttgccgatga aatcatggtc aaagaagaat atttagcact acttaattaa
    30181 aaaaggagag aaaatgaata taattgctat tatcataatt gttatttttg ttggaggtgt
    30241 cataggtgca gtaattgata accaaaaaaa atctccagag cagagagaac gtgaacttga
    30301 aacatttaga gcaaatcaag agaagaaaaa gcaagagaaa aagcagaata tcatcacttg
    30361 ccctaattgt aagtctaaag atgtgacttt cttacaacaa gacaaaaaag ccttttctgt
    30421 tggaaaggcc gttggtggag ctgttttgac tggtggagtt ggtgctttag ctggatttgc
    30481 tggcaaaaaa ggaaataaac agtggcattg ccaaaattgc ggaaatttct ttgaaacgaa
    30541 ataaaaaaat ccccacactc gtcatcgcca aatcttgagt gtgaggaaat catgtatagg
    30601 aaacaaccat tcaaaaggtc gttttcttat acccatttta tcaaaaaagt gaggtaaaat
    30661 caatgtggat ggaagaattg ccaaatggca agtttaaata ttttgagcga tataaagatc
    30721 catatactga gaaattaaaa aaagtttcag taaccatgga gaagaaaact ccacaagcaa
    30781 gaaatcaagc cgccatcttg ttgcaagaga agataaatca aaaattaggg gaaaaacaac
    30841 attctgtttc taatataact tttgaaaaac tatatgagga atttgaggaa aattggaaac
    30901 atggtgttaa aaattcaaca gtctatgctt caaaaaatgt aaaaaaagag attttaaagc
    30961 agatagaggg cgactaccta gttagaaata ttgatagacg tttattacaa aaagtaatag
    31021 atcaactatt acaagatggg agatctcata actatgtttc taaaatcaag ttcaagctca
    31081 atcagataat gaaattcgct atcagaatga attatattga tacaaatgaa atgctatttg
    31141 ttgaaacgcc tagaaaagta attacatccg acgaactcag aaagaaaaat acaaaatact
    31201 tagaccaaaa agagtttaag ttattcatcc aaaatttaaa agacgaggcc ctatgtgatt
    31261 atcgaattac aaagtatatc cgaatagcta aagttctttt tcttactggc atgaggtatg
    31321 gagagctggc agccttaaac tacaaggaag atatagattt ttctaaaaag actattcaca
    31381 tcaagcatac atacgatttc agacaaaaag agagaactac accaaagaca atcaagtccg
    31441 atagggttat aacagcacct caaaaagtgt tagatattat caaagagcaa ataatagaga
    31501 atgcgacaaa tggaattgat acagatttta ttttcatcaa tactctagga gaaccaataa
    31561 caaatgccag gattatttgt gcatggaaaa gacatggtca aaaaatcgga atagaaaaaa
    31621 acataactac acatacattt agacattctc acatatccct acttgctgag ctaggcattc
    31681 ccttgactgc catcatggat agagtaggac atagtgactc aaagaccaca ctagagattt
    31741 attcccatgt cactcaaaaa atggtatcag acatatctag taagttagaa aagattaaac
    31801 tataaattat gcccctcacc tgcccctttt tcttatacaa gacaaacaaa aaccccttaa
    31861 agtgttgatt ttaaagggtt tttaaagt
//
LOCUS       DAVDHC010000023        29887 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVDHC010000023 DAVDHC010000000
VERSION     DAVDHC010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.023"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            1..658
                     /locus_tag="VUR43_001483"
                     /pseudo
     CDS             1..658
                     /locus_tag="VUR43_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
     gene            868..3987
                     /gene="phtE"
                     /locus_tag="VUR43_001484"
     CDS             868..3987
                     /gene="phtE"
                     /locus_tag="VUR43_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET5413155.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            4213..5224
                     /locus_tag="VUR43_001485"
                     /pseudo
     CDS             4213..5224
                     /locus_tag="VUR43_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(5514..5735)
                     /locus_tag="VUR43_001486"
     CDS             complement(5514..5735)
                     /locus_tag="VUR43_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413156.1"
                     /translation="MDLFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            5700..6329
                     /locus_tag="VUR43_001487"
     CDS             5700..6329
                     /locus_tag="VUR43_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413157.1"
                     /translation="MSKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKFYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIESKANASEETSPARNAEANGDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            complement(6365..7588)
                     /gene="pepT"
                     /locus_tag="VUR43_001488"
     CDS             complement(6365..7588)
                     /gene="pepT"
                     /locus_tag="VUR43_001488"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET5413158.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            7744..8838
                     /gene="hemH"
                     /locus_tag="VUR43_001489"
     CDS             7744..8838
                     /gene="hemH"
                     /locus_tag="VUR43_001489"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET5413159.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSKQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRINENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(8880..9257)
                     /gene="mscL"
                     /locus_tag="VUR43_001490"
     CDS             complement(8880..9257)
                     /gene="mscL"
                     /locus_tag="VUR43_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET5413160.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKEE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(9339..9770)
                     /locus_tag="VUR43_001491"
     CDS             complement(9339..9770)
                     /locus_tag="VUR43_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET5413161.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     regulatory      9799..9895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            9893..10402
                     /locus_tag="VUR43_001492"
     CDS             9893..10402
                     /locus_tag="VUR43_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET5413162.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     gene            10502..10574
                     /locus_tag="VUR43_001493"
     tRNA            10502..10574
                     /locus_tag="VUR43_001493"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10535..10537,aa:Thr,seq:ggt)
     gene            11160..12236
                     /locus_tag="VUR43_001494"
     CDS             11160..12236
                     /locus_tag="VUR43_001494"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET5413163.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            12292..13227
                     /gene="dapA"
                     /locus_tag="VUR43_001495"
     CDS             12292..13227
                     /gene="dapA"
                     /locus_tag="VUR43_001495"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET5413164.1"
                     /translation="MSYRDLKECKIITAFITPFHEDGSINFDAIPALIEHLLDHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKIVNGRVPLIAGVGTNDTRDSIEFVKEVAGFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFIAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13274..14647)
                     /gene="mnmE"
                     /locus_tag="VUR43_001496"
     CDS             complement(13274..14647)
                     /gene="mnmE"
                     /locus_tag="VUR43_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET5413165.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTESFAIAQKIFKGKDL
                     SQVASHTLNYGHIVDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(14783..14965)
                     /locus_tag="VUR43_001497"
     CDS             complement(14783..14965)
                     /locus_tag="VUR43_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET5413166.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            15088..15678
                     /locus_tag="VUR43_001498"
     CDS             15088..15678
                     /locus_tag="VUR43_001498"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET5413167.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            15675..16754
                     /gene="prfA"
                     /locus_tag="VUR43_001499"
     CDS             15675..16754
                     /gene="prfA"
                     /locus_tag="VUR43_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET5413168.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            16754..17593
                     /gene="prmC"
                     /locus_tag="VUR43_001500"
     CDS             16754..17593
                     /gene="prmC"
                     /locus_tag="VUR43_001500"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET5413169.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            17580..18179
                     /locus_tag="VUR43_001501"
     CDS             17580..18179
                     /locus_tag="VUR43_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET5413170.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            18181..18612
                     /locus_tag="VUR43_001502"
     CDS             18181..18612
                     /locus_tag="VUR43_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5413171.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            18674..19930
                     /locus_tag="VUR43_001503"
     CDS             18674..19930
                     /locus_tag="VUR43_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET5413172.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            19938..20912
                     /locus_tag="VUR43_001504"
     CDS             19938..20912
                     /locus_tag="VUR43_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET5413173.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            20912..21526
                     /gene="pmp23"
                     /locus_tag="VUR43_001505"
     CDS             20912..21526
                     /gene="pmp23"
                     /locus_tag="VUR43_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET5413174.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            21600..22574
                     /locus_tag="VUR43_001506"
     CDS             21600..22574
                     /locus_tag="VUR43_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET5413175.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKEFKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDSDKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            22648..24279
                     /gene="rlmD"
                     /locus_tag="VUR43_001507"
     CDS             22648..24279
                     /gene="rlmD"
                     /locus_tag="VUR43_001507"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET5413176.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLIRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVYKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            24493..24771
                     /locus_tag="VUR43_001508"
     CDS             24493..24771
                     /locus_tag="VUR43_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413177.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAVYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            25017..25234
                     /locus_tag="VUR43_001509"
                     /pseudo
     CDS             25017..25234
                     /locus_tag="VUR43_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            25627..26652
                     /locus_tag="VUR43_001510"
     CDS             25627..26652
                     /locus_tag="VUR43_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET5413178.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            26642..27649
                     /locus_tag="VUR43_001511"
     CDS             26642..27649
                     /locus_tag="VUR43_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET5413179.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSVIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            27649..28656
                     /locus_tag="VUR43_001512"
     CDS             27649..28656
                     /locus_tag="VUR43_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET5413180.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            28656..29450
                     /locus_tag="VUR43_001513"
     CDS             28656..29450
                     /locus_tag="VUR43_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5413181.1"
                     /translation="MKGLWSNSLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
     gene            complement(29612..>29887)
                     /locus_tag="VUR43_001514"
     CDS             complement(29612..>29887)
                     /locus_tag="VUR43_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5413182.1"
                     /translation="PEKFFGLIEDNLKQVHPIFQTVFKTFLKNKEKIVNALQLPYSNA
                     KLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTNFVLSRA"
BASE COUNT         9835 a         5282 c         6027 g         8743 t
ORIGIN      
        1 cttgatcgta ttccttacaa tcttcaatat actgtagaag tcaaaaacgg tagtttaatc
       61 atacctcatt atgatcatta ccataacatc aaatttgagt ggtttgacga aggcctttat
      121 gaggcaccta aggggtatac tcttgaggat cttttggcga ctgtcaagta ctatgtcgaa
      181 catccaaacg aacgtccgca ttcagataat ggttttggta acgctagcga ccatgttcgt
      241 aaaaataagg cagaccaaga tagtaaacct gatgaagata agggacatga tgaagtaagt
      301 gagccaactc accctgaatc tgatgaaaaa gagaatcacg ctggtttaaa tccttcagca
      361 gataatcttt ataaaccaag cactgatacg gaagagacag aggaagaagc tgaagatact
      421 acagatgagg ctgaaattcc tcaagtagag cattctgtta ttaacgctaa gatagcagat
      481 gcggaggcct tgctagaaaa agtaacagat cctagtatta gacaaaatgc tatggagaca
      541 ttgactggtc taaaaagtag tcttcttctc ggaacgaaag ataataacac tatttcagca
      601 gaagtagata gtctcttggc tttgttaaaa aaaaagtcaa ccggctccta tacagtagta
      661 aaatgaatgg agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa
      721 aaacgtaaca gaaacttgac aaaagtaatt ttaaatagta aactatttac tggttaatta
      781 aatggttaaa taaccggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaac
      841 ttcatcattt attgaaatga gggatttatg aaattcagta aaaaatatat agcagctgga
      901 tcagctgtta tcgtatcctt gagtctatgt gcctatgcac taaaccagca tcgttcgcag
      961 gaaaataagg acaataatcg tgtctcttat gtagatggca gccagtcaag tcagaaaagt
     1021 gaaaacttga caccagacca ggttagccag aaagaaggaa ttcaggccga gcaaattgta
     1081 atcaaaatta cagatcaggg ctatgtaacg tcacacggtg accactatca ttactataat
     1141 gggaaagttc cttatgatgc cctctttagt gaagaactct tgatgaagga tccaaactat
     1201 caacttaaag acgctgatat tgtcaatgaa gtcaagggtg gttatatcat caaggtcgat
     1261 ggaaaatatt atgtctacct gaaagatgca gctcatgctg ataatgttcg aactaaagat
     1321 gaaatcaatc gtcaaaaaca agaacatgtc aaagataatg agaaggttaa ctctaatgtt
     1381 gctgtagcaa ggtctcaggg acgatatacg acaaatgatg gttatgtctt taatccagct
     1441 gatattatcg aagatacggg taatgcttat atcgttcctc atggaggtca ctatcactac
     1501 attcccaaaa gcgatttatc tgctagtgaa ttagcagcag ctaaagcaca tctggctgga
     1561 aaaaatatgc aaccgagtca gttaagctat tcttcaacag ctagtgacaa taacacgcaa
     1621 tctgtagcaa aaggatcaac tagcaagcca gcaaataaat ctgaaaatct ccagagtctt
     1681 ttgaaggaac tctatgattc acctagcgcc caacgttaca gtgaatcaga tggcctggtc
     1741 tttgaccctg ctaagattat cagtcgtaca ccaaatggag ttgcgattcc gcatggcgac
     1801 cattaccact ttattcctta cagcaagctt tctgccttag aagaaaagat tgccagaatg
     1861 gtgcctatca gtggaactgg ttctacagtt tctacaaatg caaaacctaa tgaagtagtg
     1921 tctagtctag gcagtctttc aagcaatcct tcttctttaa cgacaagtaa ggagctctct
     1981 tcagcatctg atggttatat ttttaatcca aaagatatcg ttgaagaaac ggctacagct
     2041 tatattgtaa gacatggtga tcatttccat tacattccaa aatcaaatca aattgggcaa
     2101 ccgactcttc caaacaatag tctagcaaca ccttctccat ctcttccaat caatccagga
     2161 acttcacatg agaaacatga agaagatgga tacggatttg atgctaatcg tattatcgct
     2221 gaagatgaat caggttttgt catgagtcac ggagaccaca atcattattt cttcaagaag
     2281 gacttgacag aagagcaaat taaggctgcg caaaaacatt tagaggaagt taaaactagt
     2341 cataatggat tagattcttt gtcatctcat gaacaggatt atccaggtaa tgccaaagaa
     2401 atgaaagatt tagataaaaa aatcgaagaa aaaattgctg gcattatgaa acaatatggt
     2461 gtcaaacgtg aaagtattgt cgtgaataaa gaaaaaaatg cgattattta tccgcatgga
     2521 gatcaccatc atgcagatcc gattgatgaa cataaaccgg ttggaattgg tcattctcac
     2581 agtaactatg aactgtttaa acccgaagaa ggagttgcta aaaaagaagg gaataaagtt
     2641 tatactggag aagaattaac gaatgttgtt aatttgttaa aaaatagtac gtttaataat
     2701 caaaacttta ctctagccaa tggtcaaaaa cgcgtttctt ttagttttcc gcctgaattg
     2761 gagaaaaaat taggtatcaa tatgctagta aaattaataa caccagatgg aaaagtattg
     2821 gagaaagtat ctggtaaagt atttggagaa ggagtaggga atattgcaaa ctttgaatta
     2881 gatcaacctt atttaccagg acaaacattt aagtatacta tcgcttcaaa agattatcca
     2941 gaagtaagtt atgatggtac atttacagtt ccaacctctt tagcttacaa aatggccagt
     3001 caaacgattt tctatccttt ccatgcaggg gatacttatt taagagtgaa ccctcaattt
     3061 gcagtgccta aaggaactga tgctttagtc agagtgtttg atgaatttca tggaaatgct
     3121 tatttagaaa ataactataa agttggtgaa atcaaattac cgattccgaa attaaaccaa
     3181 ggaacaacca gaacggccgg aaataaaatt cctgtaacct tcatggcaaa tgcttatttg
     3241 gacaatcaat cgacttatat tgtggaagta cctatcttgg aaaaagaaaa tcaaactgat
     3301 aaaccaagta ttctaccaca atttaaaagg aataaagcac aagaaaactc aaaacttgat
     3361 gaaaaggtag aagaaccaaa gactagtgag aaggtagaaa aagaaaaact ttctgaaact
     3421 gggaatagta ctagtaattc aacgttagaa gaagttccta cagtggatcc tgtacaagaa
     3481 aaagtagcaa aatttgctga aagttatggg atgaagctag aaaatgtctt gtttaatatg
     3541 gacggaacaa ttgaattata tttaccatcg ggagaagtca ttaaaaagaa tatggcagat
     3601 tttacaggag aagcacctca aggaaatggt gaaaataaac catctgaaaa tggaaaagta
     3661 tctactggaa cagttgagaa ccaaccaaca gaaaataaac cagcagattc tttaccagag
     3721 gcaccaaacg aaaaacctgt aaaaccagaa aactcaacgg ataatggaat gttgaatcca
     3781 gaagggaatg tggggagtga ccctatgtta gatccagcat tagaggaagc tccagcagta
     3841 gatcctgtac aagaaaaatt agaaaaattt acagctagtt acggattagg cttagatagt
     3901 gttatattca atatggatgg aacgattgaa ttaagattgc caagtggaga agtgataaaa
     3961 aagaatttat ctgatctcat agcgtaagga atagcagtag aaaaagtctg aatcaaaaat
     4021 gaagttctct caaaagttag aaataaaact ctgactttgg gagaatttca ttttattatt
     4081 aatatataaa atttcttgac atacaactta aaaagaggtg gaatatttac tagttaatta
     4141 attggttaat taatttattt aatcatttaa taatgaagac atcatataaa taattataga
     4201 aatgaggtaa ttatgaaatt taaaaagaaa catatagcag ctggatctgt tgttatcctt
     4261 tccttaagtc tgtgtgttta tgctctgaac caacatagct aacaggccaa tacagataaa
     4321 aatcgtgttt catatgtaaa cagtaataaa gacactaaga agactgaaaa tttgactcca
     4381 gactaggtta gtcaaaaaga aggaattcaa gcaaaacaaa ttgttattaa gattacagat
     4441 caaggttatg taacttctca tggcgatcat tatcactact ataatggtaa agttcctttt
     4501 gatgcgctct ttagtgaaga gctattaatg aaagtcccca actatcagcc gaaagatcaa
     4561 gatatcgtca gttaggttaa gggaggatat attattaagg tagatggaaa gtattatgtt
     4621 taccttaaag atcaagctca tgcagaaaat gtacgaacaa aagatgaaat caatcgccaa
     4681 aaacaagaac atggtaaaga cgataaagga gctagtgcag aagtatctgt agcaaaatta
     4741 cagggacgtt atactaccga tgatggttat atatagtgag ttgaatttag aatagcacat
     4801 catagtttct aaatcattgt tagaaattac tttaaaatcc ccttatcaat ttgctcatat
     4861 tctatttcaa tctactatag taccacatgg tggtcactat catttcattc ctgagagtga
     4921 cttgtcggca ggtgaattag cagccacata tgtctttaac cctaatgata ttgtcagaga
     4981 tacaggtgat gcttatatag taagacatgg ggatcactat cactatattc ctaagtcatc
     5041 tcttaacaat cccccatcac actctaacac ggaagaggta ggaagttctt ctagttctgt
     5101 attaagtaat ccgtcactac atgtccacca tgaggaagaa gatggtcatg gttttgatgc
     5161 caatcgaatt ataagtgaag attcagaagg ttttgtgatt cctcatggcg accacaatca
     5221 ctacatcaag gttcaaacta agggatatga agcggctttg aaaaacaaga ttccatccct
     5281 gcaatccaac tatcaacctg gaacttttga tgagaaggca gtcttggcaa aagtagatca
     5341 acttctagct gatagcagaa gcatctacaa agacaagcct atcgaacaaa gacagattga
     5401 gttagcttta ggtcagttta ctgaaagttt gaaaaaaata aaagttagtt gattgattac
     5461 ttctctaaat tttgggcaca ctaaaaagag gtcttgacac ctaaacttta aaattaaagc
     5521 atattgaatc cgtgctgctg tgcgaagcga atagcgtctt ggacgaacat tgtcttatct
     5581 ggatttctta tttctgtaag gccttgtaat cttggattat aactctcctg ttttaggagt
     5641 acatggtaga tggcaaccaa taatctgcga cagatagcaa ggaagaagta gaaagtcttt
     5701 tgagcaaggc aaatcaactc ttggaacaaa tccatgaaga aggaatcaga caatccttgg
     5761 cagaagaagt agaaaatcta aaagctgcca caaacaaggc tgatgcagac ttggatgaag
     5821 taaacagtca ggtaaaagat gtcttgactc gtatcgctag cgcccttcaa caagaaaagg
     5881 aaaatgctga gcaagatcct cagacacttg tactctatca aaaattctac gatattctca
     5941 tgtcgcttca ctcttattta gaaagtaata atggatctga tgcggacttt gataaggtgg
     6001 atgcattatt agatcaactt tctgctaata gtaaagacaa aacagcttta cttgaatcga
     6061 caaaagctat tctagttttg aatcatcaaa tcgagtcaaa agctaacgca agtgaagaaa
     6121 caagtccagc aagaaatgct gaagcaaatg gtgataacac cagtgctgag aaccaaccaa
     6181 acgcaactgc agaatctaac attgaaactg ctagcgacga aaacaaacca agcaatacaa
     6241 gagattctaa acctgctgaa tcaacttcag aaaatgaaac aacagaatct tctacaacta
     6301 ctggaaatca agaaaaacca gtagaataaa aagaaaggcg aagtagctga gccacctcgt
     6361 ctttttagcc tttataagct acgatgccaa tgatggtatc aactgcacgt tccatagtct
     6421 gaaggctaac gtattcaaaa cgtccgtgca tattttcgcc acctgcaaag atattcggag
     6481 ttgggattcc cataaaggaa atcttagagc cgtctgttcc acctcggatt ggttcgataa
     6541 taggcgtgat acctagatct tccataacgg ctttagcaat ggtaattgga gtcatatctt
     6601 tttcaatgac ttctttcata ttgtagtact ggtctgtcaa gttgagagtg acacggttgc
     6661 tcccaagttc ttcattcatc ttatcagcga tagattgcat ggatgcttta cgcgcttcaa
     6721 aggcatcttt ttcaaaatca cgaatgatgt agcttgcacg cgcctcctca acactacctg
     6781 tcacatccat tagatggtaa aaaccttggt aaccttcagt taactcaggt cggtcatttt
     6841 ctggaagttg attatgaaaa tcaattgcta gctgaagggc attgaccatc tgccctttgg
     6901 cagtaccagg gtggacatta cggccttgga aatgcaattc agcaccagcg gctgagaaag
     6961 tctcgtactg aagttcacct agtggaccac catcaacagt gtaggcaaaa tccacatcaa
     7021 aatcttctgc atcaaattta ttggcaccaa caccgatttc ttcatctgga ccaaaaccaa
     7081 cacgaatctc acagtgctta atttcaggat gagcagttag atattcaatg gctgtcataa
     7141 tttcagcaat tcctgacttg tcatcagcac ctagcaaggt tgttccatct gttgtgatga
     7201 gcgtttgtcc tggatatttt tcaagactct tgaagtcagc tggatcgagt ttgaaaccag
     7261 aattccctag ttcaatcaca ccaccatcgt agttttcaat tacctgtgga ttgactcctt
     7321 cagcattaaa atcagcagta tccatgtgcg atataaaacc aatcttacgt gttaaagacg
     7381 gatcgttggc tggcaaggtt ccaatagcaa aaccattcgg tagatagtaa acattttgca
     7441 gtccaacacg tttcatttca ggaattagga catttgttgc gaagtcaacc tgactctgtg
     7501 tacttggagt agtagtagag tgttcatcag agcgcgtgtt gaccttaacg taggttaaga
     7561 agcggtccaa gagatttgga taagtcataa aaaaaactcc ttttgaattt attttttcca
     7621 ttgtatcata gaaagaagag aaaaacaaaa gacagaagat tgagaatgtc cctatgttag
     7681 cgtttactta tcgatgaatt aatgataaaa taaacttgat aaaaacatca caaggaagca
     7741 gtcatgaaaa aagcaatttt aatgatgacc ttcggttcac cagaagagat tacctttgaa
     7801 ggtgtagctg attttttcac aaatattcgt cgtggggtga gaccccaaga ccacgagatt
     7861 cagactctct atgataatta tgtacgaatt ggaggcacgc ctctgcaaaa aattacccgt
     7921 caagaggttg ccttggtaga agctaggctg gggaatgaat acagtgtcta ctttgctaat
     7981 aagttttcca gtccctttat tccagatgtg atcggtcaaa tggaagcaga cggaattgaa
     8041 cagtgtattt gcttgatttt ggagccccat tattctttct actctgtcat gggctatgaa
     8101 aaatttttag aaagcaaaca aattcaattt ttggtcatta aggactggta tcaggaagaa
     8161 gcgctcttaa actattgggc agatgaaatt gctaagattt taaaagaaga agtaaagcaa
     8221 gacagcttta aagtcatctt ttcagcccat agtgtgccta tttttgcctt ggactttggt
     8281 gatccttata tagaccaaat tttcgaaaat agcaagctag tcgctgaaaa actgggcttg
     8341 agttcaaaac aatataccaa cacttggcag agtgagagtg atattggtat tccatggatt
     8401 aaaccagatg ttttggagta tctcagagaa cagacagaac atccagacca ttatattttt
     8461 gtacctatta gtttcatcag tgagcatatt gaggtcttgt ttgacaacga tgtggaatgt
     8521 tatgacttat gtcaggaatt tggggtaaac taccatcgtc caccaatgcc aaatacagat
     8581 tctcgtttga ttgatgcttt ggtcaataca attagaatca atgaaaatca agagtttaag
     8641 gaatttctcc cagaagaaga gacctttgat gagttagttc cttcagacga gacgaaaaac
     8701 attttggctg aatctgaaga tttacaaatg ccagaatttg tgaaaaaact gattgagaaa
     8761 aaagggcggg agaatgttaa gatgccttat cttatcaaaa aaatgcttga aaaagcaggc
     8821 aagttaccca aagagtaaag aaaaaaggat ttagctttgc gctagatcct tttaatcgat
     8881 tattttttct caaggagagc ttttatttct tgaaggactt ccaattcggt tggttttttt
     8941 tcggcagttt tttcttcctt tatgccagtc agtttctgtg ctttttcaat gcccttgata
     9001 ataaagaaga gggcggtacc cacaaagata aaattgataa tagcacttaa gaagttacca
     9061 tagccgactc catgccaaga aagttgagcg atacgttcaa ctttagcagc tttcaaagcg
     9121 ggatttaaaa taagaggagt gataatgtcg tttacaagtg aagtaacgat agcaccaaaa
     9181 gcagaggcaa tgacaacacc gacagcaagg tcaataacat ttcctcgaag caagaacgat
     9241 tttagatttt ttaacatact gttttccttt caatgtttcg tgtttcattg tatcctaaat
     9301 cattatagaa ggcaattaaa aggctcataa atggagcatt attttctaaa aatatagacc
     9361 ttgctcaaga tataattgat gataataatg aatatttgtg caattattgt ttcaatagca
     9421 tttatcttat caatgttttc agttacgaat tgccctatga tgtgaggaaa ttgggttaca
     9481 aagagaaaag ttaaaaacaa gtctaacaga aaagtagaaa ggcgagcaag agaaaatttc
     9541 actaaacgga taagtctatt tttctttttt tgcttaaata caatcgtatc atttgtgata
     9601 aaggcaaata agataccgat aatatttgcc aaggccgtag caaggagttc ctgatgactt
     9661 agttgataaa tgactagtcg tgagagaatc gaaactagag ttgtcgcaag gccaaaaaag
     9721 agataggcta agatttcatt gttaaaaaat ttttgaatag gttttttcat gctttaagta
     9781 tagcataaag caggctattg tgctatacta gtaaggttga atgaatcaac ccttggtgct
     9841 tagcttcttt caccaagcat attacacgcg gataaccgcc aaaggagaaa agatgaaaaa
     9901 attaactatt cgtgatgttg cagatattgc aatcgtcgct gctatctacg tcgttttgac
     9961 tgtcacaccg cccctaaatg ccatcagcta tggtgcttat cagtttcgta tttcagaaat
    10021 gatgaacttt atggcttttt acaatcctaa gtacatcatc ggagttacca tcggttgtat
    10081 gattgctaat ttctttagct tcggactgct agatgtcttt gttggtggtg gttcaacctt
    10141 agtattcctc agtttaggtg tttggctttt tgcaaaatat agcaaggatt acctctttaa
    10201 cggattgatt cgaaaagatc atttcttctt ttcaatcctc ttttcaattt ccatgtttac
    10261 tatcgctgca gagttaaata ttgtagcaga attaccattc ttccttactt ggtttacaac
    10321 aggaatcggt gaatttgctt cattgattat tggggcgatt attattggta aaattggtcg
    10381 tcgaattgat ttaagtaaat agaagaagat aagctaggta gttcttacct ggctttttcc
    10441 tatggaaaat ttctaaggaa acttgacaag tttttctgaa tatagtatac ttcttaagta
    10501 agctgattta gctcagttgg cagagcgcat ccatggtaag gatgaggtcg ccggttcaat
    10561 cccggcaatt agcattaaat agacagaaaa gcccttgatt tacaagggtt tttgttatgt
    10621 ctgcccccaa tttttccaat atatttctta tgcacctgtg taaataaaac taatactcaa
    10681 tgaaaatcaa agagtaaact aggaaactag ccgcaggttg ctcaaagcac tgctttgagg
    10741 ttgtagatag aactgacgaa gtcagctcaa aacatgtttt tgaggttgta gatgaaactg
    10801 acgaagtcag taaccataca tacggcaagg cgacgctgac gaagtttgaa gagattttcg
    10861 aagagtataa agagtttcgt ctgttgacaa aagtcattct ctttagtaga atagtagatg
    10921 cgatgagtcg ataggtagtc ttcgggctac tattgagcat aaggaggtca taacgcagga
    10981 gcggaccttg atgagttgtg tgaacctgct catcacatga agatgcctct taatccctag
    11041 tctagcgatt ggggattttt attttccaaa aaatgatgaa aaagctttgc aattcatgga
    11101 aaaagtagta taatacttct attatagaaa tttttagaaa attccgaaag aggttattta
    11161 tgggatatac agttgctgta gtcggcgcga caggtgctgt cggtgctcag atgataaaaa
    11221 tgttggaaga atcaacactt ccaatcgata aaatccgtta ccttgcttct gcacgttcag
    11281 caggtaagtc attgaaattt aaagatcaag atattacgat tgaagaaacg actgaaacag
    11341 cttttgaagg agttgatatt gctctctttt cagcaggtgg ttcgacatca gctaagtatg
    11401 caccatacgc agtaaaagct ggcgtggtag tagtggataa tacatcttat ttccgtcaaa
    11461 atccagatgt tcctttggtt gttccagagg tcaatgctca tgcacttgat gcccacaacg
    11521 gaatcattgc ctgccctaac tgttcaacaa tccaaatgat ggtggctctt gagccggttc
    11581 gccaaaaatg gggcttggac cgtatcattg tttcaactta tcaagccgtt tcaggtgctg
    11641 gtatgggagc aattcttgag acacaacgtg aacttcgtga ggtcttgaat gatggagtga
    11701 aaccacgtga tttgcatgcg gaaatcttgc cttcaggtgg tgacaagaaa cattatccta
    11761 tcgcctttaa cgctcttcca caaattgatg tcttcactga taatgattac acgtacgaag
    11821 agatgaagat gaccaaggaa actaagaaaa ttatggaaga tgatagcatt gcagtatctg
    11881 cgacatgtgt gcgtattcca gtcttgtcag ctcactctga gtcagtttat attgaaacaa
    11941 aggaagtggc tccaattgaa gaagtcaaag cagctatcgc atccttccca ggtgctgttc
    12001 ttgaagatga tgtagttcat caaatctatc ctcaagccat caatgcagtt ggttcacgtg
    12061 atacctttgt tggtcgtatc cgtaaagact tggatgcaga aaaaggaatt cacatgtggg
    12121 ttgtttcaga taaccttctc aaaggtgctg cttggaactc agttcagatt gctgaaactc
    12181 ttcatgaacg tggattggtt cgtccaacag ctgaattgaa atttgaatta aaatagtcat
    12241 atcgtttagg agttcagatg aactccttct ttgaaataga gaggtgtttt catgtcttat
    12301 cgagatttaa aagagtgtaa aatcatcaca gcctttatta ctcccttcca cgaggatggt
    12361 tccatcaact ttgatgctat tccagccttg attgagcatt tattggacca tcatacggat
    12421 ggaattcttc tcgcagggac cactgctgag agtccaactt tgacccacga tgaggagttg
    12481 gagttatttg cggctgtaca aaagattgtc aatggacgag ttcctttgat tgcgggtgta
    12541 ggtactaatg atacgcgtga ctctatcgag tttgtcaaag aagtagcggg attcggcggt
    12601 tttgctgctg gtcttgctat tgttccttac tacaacaaac cttctcaaga aggaatgtat
    12661 cagcatttta aagccattgc agatgcttct gacctaccaa ttattatcta taacattcca
    12721 gggcgtgtgg ttgttgaatt aactccagaa accatgcttc gcttggctga tcatccaaat
    12781 attatcggtg tcaaagaatg tactagcttg gctaatatgg cttacttgat tgagcacaaa
    12841 ccagaagagt tcttggtcta tactggtgag gatggagatg ctttccatgc catgaacctt
    12901 ggggcggatg gggttatttc tgttgcctct catacaaatg gggatgaaat gcacgagatg
    12961 tttattgcca ttgcagaaag tgatatgaag aaagccgcag ctattcaacg taaattcatt
    13021 cctaaggtta atgctctctt ctcttatcca agtcctgctc cagttaaggc agttttgaac
    13081 tacatgggat ttgaagctgg accaactcgt ctacctcttg ttccagcacc agaagaagat
    13141 gctaaacgca ttatcaaggt tgtcgtagat ggcgactacg aagcgaccaa ggcaactgta
    13201 acaggtgtct taagaccaga ttactaataa agacaataaa atccatgacc gaatgaagga
    13261 tcatggattt ttcttatttt cctaaacaga attggctaaa gagttgggtg atgagttcat
    13321 ctggagcagc atccccagtg atttctccga ggatttccca agtacgagtc aagtcaactt
    13381 gaagcaaatc aactggcatc cccagctcaa gaccttgatt aacggcttgt aggctttcaa
    13441 ctgctttttc aatcagggaa atgtgacggg cgtttgacaa gtaagtagca tcttgctcga
    13501 ccaagccagc attttcaaag aagaggttgt tgattcgctc ttcaatcttg tcgatgtttt
    13561 ggtttttaag gactgaaata cggataacgt cttcaggtag tttcgaagtt tcaatcgttt
    13621 ctggcaggtc ggttttatta agtagaataa tgcgattggt atcttggcta atttcaagaa
    13681 gttgtctgtc ttgcgcagtc agtggttcac tggcatttag cactagtaga accaagtcgg
    13741 cttccttgag ggcttttttc gaacgctcaa caccgatttg ttccactatg tcatctgttt
    13801 cacgaatacc ggctgtatca atcaatttga gaggtacacc attgatgttg acgtactctt
    13861 cgatgacatc tcgtgttgtc ccagcgatat cggttacgat agccttgtcc tcacgcaaga
    13921 ggttgttgag aaggctggat ttcccaacgt tgggacgtcc gatgatagct gttgaaattc
    13981 cttcacgaag gattttgccg cgacgggctg ttctaagaag attggttagc aattgctcaa
    14041 actccatagt cttctcacgg acaacggcag tagtagcttc ctcaacatca tcatattcag
    14101 gatagtcgat attgacctca acttgggcaa gtgtattgag gatttcttga cgggtattgt
    14161 taatgaggtc agaaagggag ccgtctaatt gcttaactgc aatgttcatg gccttgtctg
    14221 tcttggcgcg gatgatatcc atcaccgcct cggcctgtgt caaatctacg cgaccgttta
    14281 aaaaggcacg tttggtaaat tcaccaggtt cagccaatcg agctccttca cggatagcta
    14341 gctggagaat ttcattggtc accgcaatcc caccgtgggt gttaatctcg ataatatctt
    14401 cacgagtgaa ggtttttgga gatttcatgg ctcccaccat gacctcgtcc atgactttac
    14461 cagtcagagg atcaacgatg tgaccgtagt tgagagtgtg gctagcaacc tgactcaagt
    14521 cttttccttt aaaaattttt tgcgcaatag caaaactttc tgttccgctc aggcggacaa
    14581 taccaatagc tccttcacct agtggagtag agatagcagc gatggtatca aattcacgtg
    14641 taatcataat gtttccttta attaattgct cttttcttgg aattttccaa gtctcttttc
    14701 aaattgtaac aaatttagac tatttcttca atgggtgcta cttggagatt gaaaaagcct
    14761 aagcaattct gcttaagcta gcttatttgg tgcgcatttc cccctgtggg aaataagttc
    14821 cttctggcat gtcgttgatg atgacatgaa cagcagattg aggtgctcca gtgttgcgaa
    14881 caaccgcttc cgttacttcc ttagcaagag ctttcttttg ctcgagcgtg cgtccttcaa
    14941 ataaatcgat gcgtacaaat ggcataatag cttcctccac tagttttgat ttcttccatt
    15001 ttaccacatt ttgccgttta aagcttaaga aaattatgat atactagaat gtagtaaaaa
    15061 tttagaaatg gacgtgaagc aagaaacatg gcacagttgt actatcgtta tgggaccatg
    15121 aactctggta aaacgattga aattctcaaa gtggcctata actacgagga gcaaggaaaa
    15181 ggtgttgtca ttatgacctc agctctggat acgcgtgacg gtgttggcta tgtgtcgagt
    15241 cgaattggca tgaaacgccc tgcccttgcg attgaggaaa caacggatat ctttggctat
    15301 atccgagacc taccagaaaa accttactgt gtgttggtcg atgaagccca gtttctcaaa
    15361 cgccaccatg tttatgacct agctcgtgtt gtggacgagt tagacatacc cgtcatggct
    15421 tttggcttga aaaatgactt tcgcaatgaa ttgttcgaag gttccaaata tctcttgctt
    15481 ttagcggaca agattgacga aatcaagacc atctgtcagt attgcaagaa aaaggcgacc
    15541 atggtgttgc gaacacagga tggactgccc gtttacgatg gagaacagat ccagattggt
    15601 ggtaatgaaa cctatatctc ggtttgccgt aaacattatt ttgcgcctga aatcaataag
    15661 gagaatgaag aaaaatgaac atctatgatc aactacaagc tgtagaagac cgttatgaag
    15721 aactaggaga attgctgagt gaccctgatg tcgtttcaga caccaagcgt tttatggagc
    15781 tttcaaaaga agaagcttcc aatcgtgaca ccgtaatagc ctaccgtgag tataaacaag
    15841 tccttcaaaa tatcgtcgat gccgaagaga tgattaagga atcaggcgga gatgcggact
    15901 tggaagaaat ggccaagcaa gaactcaaag atgccaaggc tgaaaaagaa gaatatgaag
    15961 aaaaactgaa aattttgctc cttccaaagg atccaaacga tgacaagaat atcatccttg
    16021 aaatccgtgg agcagctggt ggagacgaag cggcactttt cgctggagat ttgctaacta
    16081 tgtaccaaaa gtatgcggaa gcccaaggtt ggcgctttga agtcatggaa gcctctatga
    16141 atggtgtcgg tggttttaaa gaagtggttg ctatggtttc aggtcagtct gtatactcta
    16201 agcttaagta tgaatcaggt gcccaccgtg tgcaacgtgt tcctgtgaca gaaagccaag
    16261 gccgtgttca tacttcgaca gcgacagttc ttgttatgcc agaagttgaa gaggttgaat
    16321 acgacattga tccaaaagac cttcgtgtcg acatctatca cgcctctggt gctggtggac
    16381 agaacgtcaa taaggttgcg actgccgttc gtatcgttca cttgccaacc aatatcaagg
    16441 ttgagatgca ggaagaacgt acccagcaga agaaccgcga gaaggctatg aagattatcc
    16501 gtgcacgcgt cgctgaccac tttgctcaga ttgctcagga tgaacaagac gctgagcgta
    16561 agtcgacaat cggtactggt gaccgttcag aacggatccg aacttataac ttcccacaaa
    16621 accgtgtcac agaccaccgt atcggcttga ccctccaaaa actagatacg attttgtctg
    16681 gtaaattgga cgaagttgtg gatgccttgg tgctttatga ccaaacacaa aaactagaag
    16741 aattaaacaa ataatgaaat tagctcaatt attttcaaat tttgaagaag agttgataag
    16801 acaaggagag gaagcggaaa gcctctcttt tgtctatcgt agtctgaaaa atctatcttt
    16861 tacagacttt atttttgccc tccagcagga ggtgacaaca gaggaagaaa aacaatttgt
    16921 agaagatatt taccagcaac tagcagctca caagccagct cagtacatca ttggacaggc
    16981 agatttttat ggaatgcatt taaaggtgga tgaacgggtt ttgattcctc gtccagaaac
    17041 agaggagtta gtggagctta ttctaactga aaatcttgag acgaatcttt cagttctgga
    17101 tattggaaca ggtagtggag ctattgctct cgctctagca aaaaatagac cagattggtc
    17161 agtgacagca gcagatgttt ctcaagaggc tttagattta gctagcgaaa atgctaaaaa
    17221 tcaaaatctt caaatatttt ttaaaaaatc tgactgtttt acagaaattt ctgaaaaata
    17281 tgatataatt gtttccaatc caccctatat ctctcgtgaa gatgagtcag aggtaggctt
    17341 gaatgtcttg tattcggagc ctcatctagc tctctttgca gacgaggatg gcctagctat
    17401 ttaccgtaga attgcggaag atgcaaaaga ctatctcaaa gatggtggta agatttacct
    17461 tgaaattgga tacaagcaag gtcaaagtgt tcccgaactt tttagaaaac atcttcctga
    17521 aaaaaaagtt cgaacactca aggaccaatt tggtcaagat aggatggtcg tggttgatga
    17581 tggacaggat tagacaagag ttggaaaatg gtggagctgt cattctgcct acagagacgg
    17641 tttatggtct ttttgccaag gccttagacg aaaaagcagt tgaccatgtt taccagctca
    17701 aacgtcgtcc tagagacaag gcgctcaatc tcaatgttgc ctctttagag gatatcttgc
    17761 acttttctaa gaatcagcca gcttatctac aaaaacttgt agagaccttt ttgccaggtc
    17821 ccttgaccat tattctcgaa gccaatgacc gagttcccta ttgggtaaat tctgaccttg
    17881 caactattgg atttcggatg cccagtcacc ctatcacact ggatttaatt cgagagacag
    17941 gtcccttgat tgggccgtct gccaatatct caggtcaggc aagtggtgta acctttgaac
    18001 aaattctgaa ggattttgac caagaggttc tgggtctgga agacgatgct tttctaactg
    18061 gacaggattc aactattgtg gatttgtctg gagacaaggt gaaaatctta cgccaaggcg
    18121 caattaaacg agaagatatt cttgctcggt tgccagagat ttcttttgag gaggcttaaa
    18181 atgctaagag atttgcaaga aacagatgtg aaagcgatat gtgacatcaa ccaagaggct
    18241 ttgggttata cttttagtcc agaggaaacg gctagccaac tagctagact gtctcaggat
    18301 tcccatcatt tcctacttgg ctatgaggat gcagctaatc atgtcttact tggatatgtc
    18361 cacgctgaag tttacgaatc actctattcc aaagcaggat ttaatatctt agctttagca
    18421 gtttcacctc aagcgcaagg tcaaggtatc ggtaaaagtt tactacaagg gttggaacaa
    18481 gaagccaaaa gatgtggtta tgggtttatc cgcttaaatt ctgccaatca tcgtctgggt
    18541 gctcatgcat tttatgaaaa agttggctat acttgtgata aaatgcagaa acggtttatt
    18601 cgcatctttt agtttgattt tcttattgta aaatcaaact aatggactag tcacacaata
    18661 aaggagaaga cctatgattt ttgacaaaga tgattttaaa gcatatgatg ctgatctctg
    18721 gaatgctatt gccaaagaag aagaacgcca acaaaataat atcgagttaa ttgcttcgga
    18781 aaacgtagtt tccaaggctg ttatggcagc tcaagggtct atcttgacaa ataaatatgc
    18841 cgagggttac ccaggacgcc gttattatgg tggaactgat gtagtagacg ttgtagagac
    18901 tcttgctatt gaacgcgcaa aagaaatttt cggtgctaaa tttgccaatg tccaaccaca
    18961 ttcaggaagc caagctaact gtgcggctta catgtccttg attgagccag gtgatacggt
    19021 tatgggaatg gatttggcat caggtggtca tttgactcat ggggctcctg ttagcttctc
    19081 tggtcaaacc tacaactttg tttcttatag tgttgatcct gaaacggaac tcttagactt
    19141 tgatgctatc ttgaaacaag cccaagaagt aaaaccaaaa ctgattgtag ctggtgcttc
    19201 agcatattct caaattatcg atttttcaaa attccgtgaa atcgcagatg ctgtcggtgc
    19261 gaagctcatg gtggacatgg cccatatcgc tggtttggtt gcggctggcc ttcatccaag
    19321 cccagttcca tacgctcata tcacaacaac aacgacccac aaaacccttc gtggacctcg
    19381 tggtggtttg attttgacca atgacgaaga acttgctaaa aaaatcaatt cagctatttt
    19441 cccaggtatt cagggcggtc ctttagagca tgttgtggcg gctaaggcag tttccttcaa
    19501 agaagttttg gatccagcct tcaaggaata tgctgccaat gtaattaaga acagcaaggc
    19561 tatggcagat gtcttcttgc aagaccctga tttccgtatt atttcaggtg gaactgaaaa
    19621 ccatctcttc cttgttgatg tgactaaggt tgtagaaaac ggaaaagttg ctcaaaactt
    19681 gctggatgaa gtcaatatta ccctaaataa aaattcaatc ccttacgaaa ccttgtcgcc
    19741 attcaagaca agtgggattc gtatcggagc agcagctatt actgcacgtg gatttggtga
    19801 agaagaaagt cgcaaagtgg ctgaactcat cattaaaacc cttaagaatt cagaaaatga
    19861 ggctgtatta gaagaagtga gaagtgcagt caaagaattg acagatgcct tcccattata
    19921 cgaggactaa aacttttatg gatatttata ttaagaaagc cattattcac cagttcagtc
    19981 cggatgatac cgagctgttc ttagcagata agtttctcaa tattactcca aaaatcgaag
    20041 aatacctacg taaaaaaatt gaacatgtgt attcagatga agccaagact gggattttcg
    20101 aagaagaaaa tcccttcttc aatcatatta cagacgattt gttggagaca tcagtaacgc
    20161 tggctaatct ctggaaagag gagtttagca tttctgaaaa tctcaagacc aatgacttga
    20221 tttttgttca attttctaaa gaaggtgtag aacatttcgc tttcttgcga attgccctgc
    20281 gggagacctt gacccacctc ggaggagaag ttgataatcc aatcaagctg actcagaata
    20341 acctgcctgg atttggaacg ggtgctgacg aggccttggt ggtcaatctt cagagtcgca
    20401 agtatcacct gattgaaaaa cgaatcaagt acaacgggac ttttttgaac tatttttcag
    20461 ataatcttct tgccgtcgct cctaagattt ctcctaaaaa atctatcaag gaactggaaa
    20521 aaacagccca gagaattgct gaatctttta acacagatga ttttcaattt caatccaagg
    20581 tcaaatcagc gattttcaac aacctagaag aaagcaatga attgtcacct gagaaattgg
    20641 ctaatgacct ttttgacaac aatctgacgg ctcgtttgag ctttattgac caagtcaaag
    20701 aagccgtacc agaacctgtt caatttgatg aaattgatgc aagtcgccaa ttaaagaaat
    20761 ttgaaaacca aaaactctcc ttatcaaatg gaattgagct catcgttccc aataacgtct
    20821 atcaagacgc cgagtctgtt gagtttatcc aaaacgaaaa tggaacctac tctatcttaa
    20881 tcaaaaatat cgaggatatc caaagtaaat aatgtttaaa cgaattcgaa gagtgcttgt
    20941 actagcagtc ttcctttttg ctggctataa agcttaccgc gttcatcaag atgtcaaaca
    21001 agtcatgacc tatcaaccca tggtgcgaga aatcttgagt gaaaaagaca ccccagcaaa
    21061 cgaagagctt gtgcttgcta tgatttatac tgaaacaaaa ggaaaagaag gcgatgttat
    21121 gcagtctagt gagtctgcaa gtggttccac caacaccatc aatgataatg cctctagcat
    21181 tcggcaaggc attcaaactc tgacaggcaa tctctatctg gcgcagaaga agggtgtaga
    21241 tatctggaca gctgttcaag cctataattt tggacctgcc tatatcgatt ttatcgccca
    21301 aaatggcaag gaaaatacct tggctctagc caaacagtac tctcgtgaga ctgttgcccc
    21361 cttgcttggt aatacgactg gaaagactta tagttatatt caccccattt ccatttttca
    21421 cggtgctgaa ctctatgtaa atggaggaaa ctattattat tctagacagg tacgacttaa
    21481 cctttacata atcaaatgtt tcactctctt ttcaacatct ggctagacca ggtgtttttg
    21541 ttataagttt tctttaagat agatatatta ctataaagaa gtaaaggagg aaattcccta
    21601 tgagaaagaa actctttctg actagtgctg cggtcttgtg ggcagtaaca gctatgaata
    21661 gcgtccatgc agcaacagat gttcaaaaag ttatcgatga aacctatgtc caacctgaat
    21721 atgtcctagg ttcctcccta tctgaagacc aaaaaaatca aactcttaaa aaactgggct
    21781 acaatgcctc aacagatacc aaagaattca agaccatgac acctgatgtt tattctaaaa
    21841 tcatgaatgt ggccaatgac tctagcttac agttgtattc atcagccaag attcaaaagc
    21901 taggtgacaa atcgccactt gaggtcaaga ttgaaacacc agaaaatatc actaaggtga
    21961 ctcaggatat gtaccgaaac gcagcagtaa cgctgggtat ggaacatgcc aaaatcactg
    22021 tagcagcccc tattccagtt acaggtgaga gtgctttggc tgggatctac tattcgctag
    22081 aagctaatgg agccaaggtg ccgcaagcca ataaagattt ggctcaagaa gagctaaagg
    22141 ctttgtcaga tatcaatgct gaaaataagg acaaatcagg ctatgatgct aataaattaa
    22201 acgttgccct agctgatatc aagtcaggac tcgccaaagc taaagaaagc aagggaaatc
    22261 tgacagaaga agatgtacgc aagattgttg aagatacctt aaaaaattac aaacttgatc
    22321 aggtcataac aggaaaccag atcaatatca tcatcaattt tgccttgaat ctctcaaaga
    22381 gtgatatcct cagcaatgca gatttcacta aaaccttaaa tgaccttaaa caaagcatcg
    22441 tatcacaagc tggcgacagt tttaaaaata tcaaccttaa ctttgattcg gataaggcgc
    22501 tagaggacgg tggtaacttc ttaagctccc tctggcaagc ccttgtcaac ttcttcaaga
    22561 gttttggttc ttaagaaatt tcatggtata atggatggta accgtaacgt tgccgtcttt
    22621 tttgtcggcc aatagaaaga gaaaagaatg ttaaagaaaa atgatattgt agaagttgaa
    22681 attgttgatt tgacccatga aggggcagga gttgccaagg tagatggttt ggtctttttt
    22741 gtagagaatg ctttaccgag tgaaaaaatt ctcatgcgtg tcctcaaggt caataaaaag
    22801 attggctttg gaaaagttga aaaatacctt gtccagtcac cacaccgtaa tcaagatcta
    22861 gatttggctt acctgcgttc aggaatcgcg gatttaggac acctttctta tccagaacag
    22921 ctcaagttta aaaccaagca agtcaaggac agtctctaca agattgctgg aattgcagat
    22981 gtagaagttg ctgaaacgct tggtatggaa catccagtca agtatcgcaa taaggcgcag
    23041 gtgcccgttc gtcgagtgaa tggtgtcttg gaaacaggat ttttccgtaa gaattcgcac
    23101 aacctcatgc cccttgaaga tttctttatc caggatcctg tcattgacca agtcgtagta
    23161 gctcttcgag acctgatccg tcgttttgat ttaaaacctt atgacgaaaa ggaacagtct
    23221 ggattaattc ggaatcttgt ggtgcgtcgt ggccactatt caggacaaat catggtcgtt
    23281 ttggtgacaa ctcgtccaaa agtttttcgt gttgaccaat tgattgaaca agttatcaag
    23341 cagttcccag agattgtgtc tgtcatgcaa aatatcaacg accagaatac caatgcgatt
    23401 tttggtaagg agtggcgcac tctttatggt caagactata ttacggacca gatgttggga
    23461 aatgacttcc aaatcgctgg cccagccttt taccaagtca atactgaaat ggcggagaaa
    23521 ctctatcaaa cagccattga ctttgcagag ttaaaaaaag atgacgtgat tattgatgcc
    23581 tattctggta ttggaaccat tggtttatca gtcgccaagc atgtcaaaga agtctacggt
    23641 gttgaactga ttccagaagc ggttgagaat agtaaaaaaa atgctcagct gaacaatatt
    23701 tcaaacgccc actatgtctg tgacacagct gaaaatgcta tgaagaattg gcttaaagat
    23761 gggattcaac caaccgttat cttggttgat cctccacgca agggcttgac agaaagcttt
    23821 atcaaagcaa gcgcccaaac aggagccgat cgcatcgcct atatctcctg caatgtcgca
    23881 accatggcgc gtgatattaa actataccaa gagttgggat atgaattgaa gaaagtccag
    23941 ccggtggatc tatttcctca aacgcatcac gtcgagacgg tagcactttt gtccaaactc
    24001 gatgtctata agcacataag tgttgaaatt gagctggatg agatggattt gacaagtgcg
    24061 gagagcaaag caacatatgc tcaaatcaaa gaatatgttt ggaataaatt tgaattaaaa
    24121 gtttcgacat tatatattgc acagataaaa aagaaatgtg gaatagaatt acgagaacat
    24181 tacaacaagt ctaaaaagga taaacaaatt attccacagt gtacacctga aaaagaagaa
    24241 gccatcatgg atgctttgag acacttcaaa atgatttaat agaaaagaat gacagtatat
    24301 gactttctgc atttattaca ttcctacttg gtataggaac agctattatt cctttcttgc
    24361 aaggtatcaa ttagaaaata ggctcaatat aaagattgat aggatcattt ttatatttaa
    24421 aggagcgttg aaatgattga taaaggcaac aaaaaatttt aggataaatt tgctaagttg
    24481 tatgcccctt ttatgaaaaa agataaagag gtttatgata aagtttgtga atatcttagt
    24541 cctcatttga ataaagatat ggaggtgctt gaacttgctt gttggtttcg tgtcataaca
    24601 gttatagagg caaatagtta tgtaaatata aggagttcaa gacttctacc aaagtttaaa
    24661 actcaaaaaa taaatagttg gtgtgctgtt tatagtatcc attttaataa tggatattgt
    24721 aagcagcata ccaatgaatt taaagattct ttaaagagtc ttattttgtg atgaaaattt
    24781 aatatgtaaa tctcagacga tagaaattaa aaactctatc gtctttttta tactcaaaat
    24841 taggaggtaa aaatggtaag gataagaggt cccacttaaa acaatttatg gcaaaataag
    24901 gacggaataa cacaacaaat tctctaaaac aaatcactaa atcaatgtaa gattgaatga
    24961 aatcaatatt tatgctataa ttaaataaat ttaatgaaga aaaaaagagg gatattatgg
    25021 cacttaacta taaaccatta tggatacagt tagcaaaaaa agactaaaga aaacagatgt
    25081 aatagctatg gcaggactta caacaaatgt tatggcacaa atgggaaagg ataaaccaat
    25141 tacatttaag aatttagaaa gaatatgtaa ggctttatct tgcactccta atgatattat
    25201 tagttttgaa gataatttta gtgacgagga atagaaaatg actttaagga cagaagatca
    25261 agttagggat tatgcaagag aagtataggc tttaatgaag ttgaagaaaa catcaatcaa
    25321 ggtactggtc aaataactac ttttaatcaa ttaggcttca agggatattc agataagcca
    25381 gatggttggt atttacctaa aaatatgaat gatgtagcaa taatccttga aacaaaatca
    25441 gaagaaagag atattagcaa acaaattttt attgatgagt taatgaaaaa tatagacata
    25501 atttaactaa aaataaaaac tagatccttt tttgaaaaaa ttatattatt aaatttgtaa
    25561 ctgtatctat tgacaatgat aattattatc gatacaatag acttgaaata tgtttaagga
    25621 gtttttatga aaaacaaatt ttttctaata gctattttag ctatgtgtat agtttttagc
    25681 gcttgttctt ctaattctgt taaaaatgaa gaaaatactt ctaaagagca tgcgcctgat
    25741 aaaatagttt tagatcatgc tttcggtcaa actatattag ataaaaaacc tgaaagagtt
    25801 gcaactattg cttggggaaa tcatgatgta gcattagctt taggaatagt tcctgttgga
    25861 ttttcaaaag caaattacgg tgtaagtgct gataaaggag ttttaccatg gacagaagaa
    25921 aaaatcaaag aactaaatgg taaagctaac ctatttgacg atttggatgg acttaacttt
    25981 gaagcaatat caaattctaa accagatgtt atcttagcag gttattctgg tataactaaa
    26041 gaagattatg acactctatc aaaaattgct cctgtagcag catacaaatc taaaccttgg
    26101 caaactttat ggagagatat gattaaaatt gattcaaaag ccttaggtat ggaaaaagaa
    26161 ggtgatgagt taatcaaaaa tactgaagct cgtatatcca aagaattaga aaaacatcca
    26221 gaaatcaaag gaaaaatcaa aggaaaaaaa gtattattta ctatgattaa tgctgcagat
    26281 acatcaaaat tctggattta tactagcaaa gatccaagag caaattattt aacagattta
    26341 ggtctagttt tccctgaatc attaaaagaa tttgagagtg aagatagttt tgcaaaggaa
    26401 atttctgcag aagaagcaaa taagataaat gatgctgatg taatcataac ttatggtgat
    26461 gataaaactc ttgaagcttt acaaaaagat cctcttttag gtaaaataaa tgcaattaaa
    26521 aatggtgccg ttgctgtaat tccagataat acaccgttag cagcctcatg cactccaaca
    26581 ccactttcaa taaactatac tattgaagaa tacctaaatc ttttaggaaa tgcatgcaaa
    26641 aatgcgaaat aaaaaacaaa taaacctagg cataattttt gtaatctgcc taggtcttct
    26701 tattacaata tttttgtcat taaagcttgg aacaaaagaa attaatatca gagatttttt
    26761 agcagctttt ggaatgggca atacaaatga tgattttatt aaatcaatta tatataaaag
    26821 aatacctaga actatttttg caattttagc aggttctagt cttgccataa gcggtgtatt
    26881 gatgcaatca gttactagaa acccaatagc tgatccaggt atactcggta taaacacagg
    26941 agcaagtctt agtgtagtaa ttggtctttc ttttttagga atttcatcaa gcataagcca
    27001 tataagtttt gcaatcattg gtggcttagt aagtgtaatt tttgtatacg cgattgctgt
    27061 aagcggaaaa gcaggcctta cccctataaa actagcctta tcaggaactt gtgttagtat
    27121 ggctttaagc agttttgtaa gttttttaat tttaccgaat aataacgtct tagacaaatt
    27181 tagattttgg caaataggta gccttggagc agctacatta tcttctatat ctacactact
    27241 accttttata attttaggtc acttgatagc tatatttatt tcatcagatt taaacgcttt
    27301 agctatgggt gatgaaatgg ctgttggtct tggagttaat gttaatagga taagatcact
    27361 tgcaataatt gcaagtgtgc ttttatgttc aagtattact gcaattggtg gacctattgg
    27421 cttcgtaggt cttatagttc ctcacttttg tggcttattt ataagcaaag atatacgcac
    27481 aatgaccatt tcttcatctt ttataggtgc agagctcttg cttatatgtg atataatcgg
    27541 ccgtatgtta ggtaaaccag gtgaaattga agtagggata attactgcaa taatcggggg
    27601 tccagtactt atttatgtaa ctatgaaaaa tagaggggtt aataactaat gcaaaattta
    27661 attataggta ttcaaaaaag aaaaaataga ataacactat tttcctcact atttttatta
    27721 ataataatca gtctatcatt tttcatttta cttatcggag atgaaagtta ttctttttca
    27781 actttgatta aagtcttaaa tagtgaaact gttcctggag ctagtttttc gattatggaa
    27841 attagattac caaaattatt agcaggaatt atagctggct ggtcttttgg attggcagga
    27901 tttatctttc aaactatgtt aagaaatcct cttgcaagtc ctgatataat cggtgtcaca
    27961 agttcttcat ctattgcagc ggtcttttgc atattggtat taaaaacaaa tagtttaact
    28021 actggaatta tttcaataac ttgtggacta acatcatctt taatattatt tttactagct
    28081 aaaaaagatg gtttttcagc agcaagactg ataatattag gtattggttt tcaagctgtc
    28141 acaagagcag gcacctcatt tttattgttg aaagtagcaa gatatgaatt acaagaagtt
    28201 atgagatggc tcagtggctc tttatctttt acaaagttag atgacatacc tcttgttcta
    28261 atagtaagta ttattgctac tatattagtt ttatttttta ataaaagact agaaattatt
    28321 gaacttggtg aagaaatagc aatcggactt ggagcaaatc ccgagctttc aaggcttgtt
    28381 ttaatttttt gcgctgtatc tttaactgct ttttctactt caattacagg accaatagct
    28441 tgtatatctt ttttagctgg tcccatagcc ttaaatattg gcaagaaaag aagcccaata
    28501 ttagctggat tggttggaat tttactagtt ttgttatcag acatattctc tcaaaatatt
    28561 ttaccagcta gatatccagt aggtgttgta actggcttgt taggttcacc atacttaata
    28621 tacttactaa taaaaatgaa caggaggaat atataatgaa aggtctgtgg tcaaatagtc
    28681 ttacctgcgg ttatgatgaa aaaataatct tggaaaatat aaatataaaa atacctgaag
    28741 aaaaaatatc agttattatt gggtcaaatg gttgtgggaa atcaacactc attaaaacct
    28801 tgtctcgact tataaagcca ttagagggag aagtattgct tgataataaa tcaattaatt
    28861 cttataaaga aaaagattta gcaaaacaca tagctatatt acctcaatct ccaataatcc
    28921 ctgaatcaat aacagtagct gatcttgtaa gccgtggtcg tttcccctac agaaagcctt
    28981 ttaagagtct tggaaaagat gaccttgaaa taataaacag atcaatggtt aaggccaatg
    29041 ttgaagatct agcaaataac ctagttgaag aactttctgg gggtcaaagg caaagagtat
    29101 ggatagctct agccctagcc caagatacaa gtatcctact tttagatgag ccaactactt
    29161 acttggatat ctcatatcaa atagaactat tagacctctt gactgatcta aaccaaaaat
    29221 ataagacaac catttgcatg attttgcacg atataaatct aacagcaaga tacgctgatt
    29281 acctatttgc aattaaagaa ggtaaacttg ttgcagaggg aaagcctgaa gatatactaa
    29341 atgataaact agttaaagat atctttaatc ttgaagcaaa aattatacgt gaccctattt
    29401 ccaattcgcc tctaatgatt cctattggca agcaccatgt taactcttaa taattgaata
    29461 ttggaattca tttaaaagtc gcaaattttg aactgaccct caaaagttag gccaaaaaac
    29521 taactaaagg aggtcagttt tttagactct ttgtcaactg tagtgggttg aaaaaaaggg
    29581 ctctttgtca actgcagtgg gttgaagtcg gctaagctcg agaaaggaca aaattcgtcc
    29641 tttctttttt gatgttcaga gcgataaaaa tccttttttt gaagttttca aagttccgaa
    29701 aaccaaaggc gtttcgtttg ataagtttga tgagattatt ggtcgcttcc aattttgcgt
    29761 tggaataagg taattgaaga gcgttgacga ttttttcttt gttctttaga aaggttttaa
    29821 agacagtctg aaaaatagga tgaacctgct tcagattgtc ctcaatgagt ccgaaaaatt
    29881 tctcagg
//
LOCUS       DAVDHC010000024        29662 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVDHC010000024 DAVDHC010000000
VERSION     DAVDHC010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.024"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(202..1626)
                     /locus_tag="VUR43_001515"
     CDS             complement(202..1626)
                     /locus_tag="VUR43_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET5413183.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEATSKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2171..4450)
                     /gene="pulA"
                     /locus_tag="VUR43_001516"
     CDS             complement(2171..4450)
                     /gene="pulA"
                     /locus_tag="VUR43_001516"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET5413184.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4562..6520)
                     /gene="ligA"
                     /locus_tag="VUR43_001517"
     CDS             complement(4562..6520)
                     /gene="ligA"
                     /locus_tag="VUR43_001517"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET5413185.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTNLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6613..7806)
                     /locus_tag="VUR43_001518"
     CDS             complement(6613..7806)
                     /locus_tag="VUR43_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5413186.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIG
                     ALIVANIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLV
                     LQFASLHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWH
                     QQEIFFLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASK
                     IKANIYNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVE
                     SEFLGRVLSTIFTLAILFMPIAKGFMTVLQSVHLSSFLIIGSGVIILSCISFIYVRTH
                     FEKLI"
     gene            complement(7886..8749)
                     /locus_tag="VUR43_001519"
     CDS             complement(7886..8749)
                     /locus_tag="VUR43_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET5413187.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8752..10653)
                     /locus_tag="VUR43_001520"
     CDS             complement(8752..10653)
                     /locus_tag="VUR43_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET5413188.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALLIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQVQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
     gene            complement(11079..11354)
                     /locus_tag="VUR43_001521"
     CDS             complement(11079..11354)
                     /locus_tag="VUR43_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET5413189.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(11460..12299)
                     /locus_tag="VUR43_001522"
     CDS             complement(11460..12299)
                     /locus_tag="VUR43_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET5413190.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRAVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            12441..13289
                     /locus_tag="VUR43_001523"
     CDS             12441..13289
                     /locus_tag="VUR43_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET5413191.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     DDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(13382..14299)
                     /locus_tag="VUR43_001524"
     CDS             complement(13382..14299)
                     /locus_tag="VUR43_001524"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET5413192.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            14737..14942
                     /locus_tag="VUR43_001525"
                     /pseudo
     CDS             14737..14942
                     /locus_tag="VUR43_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(15147..15440)
                     /gene="rpmA"
                     /locus_tag="VUR43_001526"
     CDS             complement(15147..15440)
                     /gene="rpmA"
                     /locus_tag="VUR43_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET5413193.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(15457..15801)
                     /locus_tag="VUR43_001527"
     CDS             complement(15457..15801)
                     /locus_tag="VUR43_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET5413194.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(15817..16131)
                     /gene="rplU"
                     /locus_tag="VUR43_001528"
     CDS             complement(15817..16131)
                     /gene="rplU"
                     /locus_tag="VUR43_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET5413195.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(16167..16254)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(16319..17017)
                     /locus_tag="VUR43_001529"
     CDS             complement(16319..17017)
                     /locus_tag="VUR43_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET5413196.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            17419..17718
                     /locus_tag="VUR43_001530"
     CDS             17419..17718
                     /locus_tag="VUR43_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET5413197.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            complement(18118..19092)
                     /gene="pta"
                     /locus_tag="VUR43_001531"
     CDS             complement(18118..19092)
                     /gene="pta"
                     /locus_tag="VUR43_001531"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET5413198.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(19136..20032)
                     /locus_tag="VUR43_001532"
     CDS             complement(19136..20032)
                     /locus_tag="VUR43_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET5413199.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(20029..20847)
                     /locus_tag="VUR43_001533"
     CDS             complement(20029..20847)
                     /locus_tag="VUR43_001533"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET5413200.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(20831..21502)
                     /locus_tag="VUR43_001534"
     CDS             complement(20831..21502)
                     /locus_tag="VUR43_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET5413201.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            21630..22199
                     /locus_tag="VUR43_001535"
     CDS             21630..22199
                     /locus_tag="VUR43_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET5413202.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            22312..23271
                     /locus_tag="VUR43_001536"
     CDS             22312..23271
                     /locus_tag="VUR43_001536"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET5413203.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            23281..24396
                     /locus_tag="VUR43_001537"
     CDS             23281..24396
                     /locus_tag="VUR43_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET5413204.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQKLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            24401..24748
                     /locus_tag="VUR43_001538"
     CDS             24401..24748
                     /locus_tag="VUR43_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET5413205.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            24756..24971
                     /locus_tag="VUR43_001539"
     CDS             24756..24971
                     /locus_tag="VUR43_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET5413206.1"
                     /translation="MFELTYKDCYHVERTLKYEEHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            25054..25695
                     /locus_tag="VUR43_001540"
     CDS             25054..25695
                     /locus_tag="VUR43_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET5413207.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            25713..26402
                     /locus_tag="VUR43_001541"
     CDS             25713..26402
                     /locus_tag="VUR43_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET5413208.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(26399..27079)
                     /gene="radC"
                     /locus_tag="VUR43_001542"
     CDS             complement(26399..27079)
                     /gene="radC"
                     /locus_tag="VUR43_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET5413209.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLETE
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(27122..29413)
                     /gene="pcrA"
                     /locus_tag="VUR43_001543"
     CDS             complement(27122..29413)
                     /gene="pcrA"
                     /locus_tag="VUR43_001543"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET5413210.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVVRT
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
BASE COUNT         9051 a         6340 c         5346 g         8925 t
ORIGIN      
        1 actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
       61 tctagcaatg ttttagaagt agagctgtac tattctagtt tcaatatact ataataccaa
      121 aaagttcgta ttttttctat aattattatt attttatagc aaaaaaataa aaccaggaga
      181 acaatttcct gattttacac gttatttcac atcaaaaaca atggatttga catttgtcat
      241 cgcttcaatg ctatatttaa ttccttgcac tccagctcca gaacctttga caccaaggaa
      301 tgggaaatta tctggaccac gctgggtttt attattaatg tggactgtac ctacttcaag
      361 tttttcagca atttcaaagg cttttttgaa atcatttgta aagactgatg attgaaggcc
      421 gaattcagat tcgttggcaa aggcaatagc ttcctctaca ctagccacac gaatgattgg
      481 taaaacagga ccaaatggct cttcccatgc cactttcata tcttttgtaa cttggtcaaa
      541 aagcactggc cagaggagat tgccctcacg tttgattggt gtaagagcct gagcctcttt
      601 ttcttgtgca tcctcaatca agccccaaat gaagtcggct gaagcattgt caataacagg
      661 tgtaatatca gcattgtcaa atggatcacc aactgttaat ttagaaactt cttcctgaag
      721 caaagtagct aatttctctg ctacactttc gagaacaatg acacgtttaa tggccgtgca
      781 acgttgtcct gagtagctaa aggctcccgc aacaatttgc ttggcagcat gttccaaatc
      841 tgcatcttct agtacaagag ctgcatcttt cccaccaagt tccaacatga taggacgcat
      901 accagctaaa cgaccaatac gttctccaat aggagttgaa cctgtaaagt tgatgaagtt
      961 gacttctttg tgctcaatga tataatcccc aatttctgaa ccacgacctg taatggtgtt
     1021 gaaaacacct gccggaatcc ctgcttcttc aaatgcttta gccaacaaga gtccagaaat
     1081 ggaaccttgt gttggtggct taaacatgac cacattccct gcaatcaagg caggtgcaat
     1141 tttagaagca gataaattaa ctggataatt aaagggagca atcgctagca cgataccaac
     1201 tggttcacga cggacaacag ccagtttgtt tttacttgtt gcctcaaaac caccaccttc
     1261 cattgcttgt ccagtgatac ggagaccttc ctcagcagca taacgaatca agtctgctgt
     1321 acgcactact tctccaattg ctgctttaat cccttttgct acttctttgg caaggatagt
     1381 accaatttct tccttatcgc gttctaaaat agctgctgtt ttatgcaaat aagccgcacg
     1441 ttcaactgct gataaagctc gccatgctgg cagggctgca cgcgcagctt gcatagcctc
     1501 atcagcttca gtctgagtca tggctggaac tgtacccaat tcttcttgat tgattggtga
     1561 ataaatcgta atttcttgtt cagatgattt ccattttcca tttactaaat tctgatatct
     1621 tgtcaaattc ttgtcctcct gaaaatgatt aagatatatt ttaccaaatt ttcagaaaat
     1681 cacaaccctt tttgcaaaat ttttgagatt attttcacaa acttgatttt tcaaagtata
     1741 ctcaataaaa attaaaaaaa tccactacgt caaggcgagg ctaatgtggt ttgaagaaat
     1801 tttcgaagag cgtgaatgag tatcatctat agtaaaataa aaaaactgaa caatttggtt
     1861 ggggacagcc aaaccaattt ctcacaatgt tttagaaaca agggtgtgct attccaattt
     1921 caggctacta taactgtcat agattgctga aacaaagtct aggtaaaagt cttcataata
     1981 aaaagacccc ctatcaagtg ttcaaaaact ttgataggag gtcttgtttt gtgaaaatat
     2041 ttatcaaatt ttctatacaa gtgagctgtt agccaggttc tttctattct ttcaatttca
     2101 atgaatggat tttttactaa tactcataac tgggaatttg tctgtgtaaa aatagcgaga
     2161 tagatggtat ttataaaaca ctcaagacag ctagactaat atcatttaaa acattatctt
     2221 cttttgagcg actgttggtt accaacatag ctaaatttcc tgcattttca aattgatagg
     2281 gttctgattt agcattcaca accaccaaga gatgttcttt gccgtgaact tcatagataa
     2341 ggtagccgct atgttcaatc gcagaatgca caaagacatg atggtaaatt tcatcatagc
     2401 tagagtaaga aaaggcacca gtttttgtct tcaatcggat gacttgacgg ataaactcaa
     2461 tactgtcttg acgctcatta atcaagttcc agttcacttg gttcacactg tcaggagcat
     2521 tatagctatt catcgcacgc tctctatcat catgggtcaa ctcaccattt tcaccagtcg
     2581 caaccagttt ggtacgacca aattcttgac cgatttccat aaaggccatc ccctgcatga
     2641 gcagattcat ggctgtggca gtttcgacct tgcgcatgat ttgctctgaa ctttggtctg
     2701 gatgaagggt tgccaataaa tcgtgaagat tgtaattgtc atgggcttct acatagttaa
     2761 gcacctgatt tggatgtgta tagcttccta attcacgact tcctaggatt gctttagcta
     2821 gaattggctc tgtcgcagca ccactgacaa aacctgactt gatagcacca taaacttctc
     2881 cccctttgac agcatcgcgc tgattgtcat taaagaaacc aatatttggc atctggtagg
     2941 cattgtcctt cttggcctta tcataagggg caagacctgt tcccatatcc catccttctc
     3001 catagaggat aatgttggag tcgatttcat ccaagctttg acgaatcatc tgcatggtct
     3061 tgacatcatg aatccccatc aagtcaaaac ggaagccgtc aatattatat tcctgcaccc
     3121 agtatagaag agaatcaatc atatacttgc gaaacatttc gtgttcactg gctgtttcat
     3181 ttccaacacc cgttccattc tggaaggtac catctggatt catacgataa tagtaatcag
     3241 ggactgttgt ttggaatggt gcatcaacaa ctgagaaggt atggttatag actacatcca
     3301 taatgactcc aatacccgca tcgtgataag cttgaaccat caccttcaaa tcacgaatga
     3361 cctgagctgg atcatctgga ttagttgaaa aactagtttc tggcgcgtta tagttttgtg
     3421 gatcataacc ccagttgtag gttacatttc catcctcatc gtattcttta tgacggtctg
     3481 caattggttg caattgaaca taattgtagc ccagcttctt gatgtaatca aaagcagttg
     3541 actggccgta ttggttaact gttccagcct gagcagcacc caagaaagtt cctcgaagat
     3601 gttcatctac acccgatgta ggtgatttag tcaaatcacg aatatgcatt tcacagataa
     3661 ctgccttaca tggattttcc aagcgccaag tagcctccga accgtgctta acctcgaagt
     3721 tttcaacttg cttttctaca tggctcagaa tagctgaacg tttgccatca gggctggtcg
     3781 cgattgtata aggatcacgt gtcagtgttt ggtgatgagg gaattggact tgatactgat
     3841 aagtcttacc taccaaatct tcttcaacat ccaaactcca gacaccgatt gtattgtcct
     3901 tatgattata agagtagcta ttgcctcttt tcatctcaaa agtcttccaa acgggtgcat
     3961 cattagcagc tgattcataa acgacaactt gcacttctgt cgctgtaggt gaccagaggg
     4021 aaaaatgagc ctgattgtcc tctacacggc aacccaattc tccttggtaa ccccaatgat
     4081 gatcaaaact agcactgtta atggccttat caaaggcaaa aggattttga tttttataga
     4141 aaggactggc aatagcagga ttttcagagt aataaatcct atcatcgcct tccaaaatcc
     4201 agacctctgt taatagggga tagtgattaa aacggataga atattcttta ctagtttgac
     4261 ctgtatgaac cacaaaattc aagctttcta taacatgtga acttgggtgt tcaaagctaa
     4321 ataaagctcc aaaataatct tctttgtagg ttagcaaatc aattcgttga tcctgacttt
     4381 ttacaaagga gcaagtgtca tattctccat tcttacgatg gtaatgaatg cgcatagggt
     4441 agttatacat tttttatttt tcctttttac tttgtttcta tttcactaat aaatttttgt
     4501 caatctcgtc tcaattaaca gacatagtca tattctctaa actctgtttt taaacgatcc
     4561 attacaaact ttctagccat gcctcatctc tgacctggat accaagttct tgtgcttttt
     4621 gcagcttact tccagcgtct gcacctacca cgacgaggtt ggtcttttta gaaacactac
     4681 ctgtcacttt ggcacccaga ctttcgagtt tacttttagc ttctgagcgc ttgagtcgtt
     4741 ccaattttcc tgtcaatacc acggtcaaac ctgacaaggc cgcatccgct actaccgtct
     4801 gtcctttata gtccagattg accccagttt ctttcaattc tctgagcaga atttcagagc
     4861 cttctgtcgc aaaataagtc tgaagacttt tggcaatcac gccacctaga ctttcaatac
     4921 tagccacttc ctctgaatct gcctgataca gattttcaat tgaatggaaa tattgaagta
     4981 aaagctgact agccttgctt ccgacatgac gaattcccaa accaaataag agcttctcgg
     5041 cagaattttc ctttgacgct tggatagcct gatacagttt agcagcggac ttttccttaa
     5101 ccccctctaa aaggaggaaa tcctcttctt gcaaacgata aatatccgcc acatccttga
     5161 ctaaattagc agcaaaaagc ttctcaacaa tagatggacc aaggcctgta atattcatag
     5221 catcacgaga agcaaagtga atcaagcctt ccatgatttg agcagggcaa cgcggattga
     5281 tacaacgtag ggccacttca tcttcaaagt gcaacaagtc agagttacaa cttggacagt
     5341 ttgtagggat atctagtttt tcttcagaaa cccgtttgga ctctaccaca cgtaaaacgg
     5401 cagggatgat gtcaccagcc ttatatacaa tgaccgtatc gtcttttcgg atatcttttt
     5461 cagcaatata atctacattg tgcagggtcg cacggctaac agtcgtaccg gcaagttgta
     5521 ctggtgttag attagcagtt ggagttacaa caccggtacg gccaactgtc cagtcaactg
     5581 ataagagttg agcttctttt tcttcagcag ggaacttgta ggctactgcc cactttggag
     5641 ccttaacggt aaaaccaagt tcttcttgac ttgctaggtc gttgaccttg attaccactc
     5701 catcaatatc gtaaggtaga ttttcccgtt cctgtcctac ttcttggata aaattccaga
     5761 tttcatctat gttttcagcc aagattcgct taggattgac cacaaaacct agttgttcta
     5821 ggtacttcaa acccttttct tggctatcac gagttgaagg gctggcttct tgatagagaa
     5881 acgttgcaag attacgcttg gcaactactg ctgtatccaa ctgacgcaga gttcctgctg
     5941 ccgcattacg aggattagca aattcaggct ctccattttc ttggcgcgct tggttaactt
     6001 ggtcaaagga agcgcgtggc atgtaacatt ccccacgaac tgtgatatct agttcttctg
     6061 gcaaagtcaa agggatgtcc ttaacacgct tgaggttttc tgtgatattt tcaccaattg
     6121 aaccatctcc acgtgttacc ccagcaacca aaatcccctt ttcataagtc agcgagatag
     6181 ataagccatc gattttcagc tcacaaatat aggtcggatg agccacttcc ttacgaacac
     6241 gcgcatcaaa agcatctagc tcctcacgtg aaaaagcatc ctgcaaacta taaagaggat
     6301 actgatgact gtatttttca aaaccatcta aaaccttgcc accaacacga tgagtcggac
     6361 tgtctgctag cacttgctct ggataagcag tttctaactc gaccaactca cggtaaaggc
     6421 ggtcatactc actgtctgaa accgagggat tatcgctggt atagtactca gtcgcatagc
     6481 gattgagcaa agcgactaac tcattcattc ttttattcat aagaccattt taccataaaa
     6541 caagccctcc tcacaaacga gaagggcgga aaaaacactt agtttgaaat tatttttgaa
     6601 actcaagcaa ccttatatca atttttcaaa atgagttcga acataaataa acgatataca
     6661 agacaagatg ataacaccac ttccaattat caggaaagaa gagagatgta cactttgcaa
     6721 gactgtcata aatccttttg caataggcat aaatagaata gctaaggtaa aaattgtact
     6781 cagtactctc ccaagaaatt cgctctcaac cttggtttgt acttgagtaa aaaagtgaat
     6841 attaaaaatc gtcataaaca attcacaaac taaatttcca gaaaaggaaa gaaaagttgg
     6901 aagtggtaat cccatcataa aaactccaac acctgtcaaa gccagtaaaa tcaaaagatt
     6961 ataaatatta gctttaattt tactagctag aagagcccca atgatggaac caatagcccc
     7021 catagttaaa atacttgcat aggctccttc tgacccgtaa agctgattcg aaaagggaag
     7081 tagaaattca aaagctgcaa aaaagaaatt aacgctggaa gctaccagca aaaggaagaa
     7141 aatttcttgc tgatgccaga tatagtgtaa cccatccttg atatctacaa aaatatctct
     7201 cccagtaaaa gcctttttct cttgaacttt tgcttcctct tttggaagga aagccactag
     7261 aacaaaagca atgaaaaaag tcagcgagtc tagcagtagc gtcatatgga gacttgcaaa
     7321 ctgtaaaaca aggaaggaaa gaacaggaga gctaacacct acaacctgca aaaccagctc
     7381 taagcgagaa ttatagatca caatctcatc tttctccacc acttcagtta tgatagcttt
     7441 attggctgtg cgagaaaagg caaaagcaat agcctgcaca atgttagcaa caatcaaagc
     7501 gccaatcatc cagctatcat tccttatgaa agaaatagcc agacaaagaa tcccacaaac
     7561 aagatctgcc gtcattaaaa tcttacgacg agaaaaacgg tctgaaataa ctccaccaaa
     7621 gggattgacg agaatagatg tgacgagaat agatgtgacg agctcagaaa tctgatacat
     7681 tcctaaaact gtctgtccta tagtccccat agaagccaac cagacactat ttccataatc
     7741 atagagcata tttcccattt tattgatagc cccacggcta atcaactgca ctgcatagcg
     7801 attcatatta aagctcctct caaattttga aactattgta tcaaaaccga aaggagcttt
     7861 ttattttttc ccttatttgg gaaaattaac ttttgacaaa tttttcgtag tgttcctgat
     7921 aataggctac ttgctctgga agacctaaca catcaaaaat atgcatggcc tcttgcatct
     7981 gcttacagcc ttctttacac tgtccttttt gatataaggc caaacctttt aaataatgga
     8041 aaacattacg ctcataaagc ttaatacctt tgtcaataat cttctctgta taagcctcaa
     8101 aatagttggc attataaaaa gaagaatgct ctaaacaatg ctggtaacaa ttgagggcca
     8161 aaattaacac taatctctta tggcgactaa tctcttggta aaattcctcc ctctccataa
     8221 cttctctacc aatccgagtg acatagtcta catcgtagaa actatagagg ttaccgaaaa
     8281 gaatcaactc atacatggtc cattcttctg ttttgaagag ataatctgct accttatcca
     8341 aatcatcctg cttcatatca taactcgcat ctctttgaca aatcagacct tgtagcaaaa
     8401 tccagttcag ctcaaaataa aggggagtcg tcgaactctt agacttttca agttgttctc
     8461 tttgaagctt ttgaaaacct gcaatatcgt ttgaatagta aagtgggata atctgtgcca
     8521 tcatagacac atgttcatga ttatgaaaat tccttgcctt atccatgaaa ttttcgattg
     8581 ttacatgaat gttatccaaa atctcaaaga aacgggagac tgccaggtca gactccccaa
     8641 gctcaaagcg agataactga gaggtagagc aggattcgcc tgctgcttcc tttaaagaat
     8701 aatttccact tgttcgaaat tcacgaaata cttttccaag atgttccatc tttacacctg
     8761 ctctgataat tcttcccact caagcatagc ttcttcctga cgatggctga ttttgtccag
     8821 ctcagcctgt aattccatga gtttgtcggc atcgtttgtt tccaacattt gttcagaaat
     8881 ggcttggctt tgactttcta gctcttcaat ttcagcttct agactttcga tttgtcgcat
     8941 gagtttgcga acttcttttt gactttcttt ctggacctga tagtcattga ctggacttgc
     9001 ttcctttgct tgattgctag ttgaagcttc ctcagtctga ctcatttctg ctgttacttt
     9061 cttctcaaca tagtagtcgt aatctccaag gtagagagtt gaaccattct cagacaattc
     9121 caaaacatga gttgccacac gattgataaa gtaacgatca tgactgacaa acagcaaggt
     9181 accatcaaag tcaatcaagg cattttctag cacttcctta ctatcaatat ccaagtggtt
     9241 ggtcggctca tccagaatca aaaagttatt gttttccata gacaatttag ctaaaagcaa
     9301 acgagctttt tcgccaccag atagcatgcc gactgatttt ttaacatcat ctcctgagaa
     9361 aaggaaggct ccaagacggt tgcggatttc aacttctggt gtcagtttga aatcattcca
     9421 gagttcatcc agcaccgtat tacttggtgt cagcttgctt tgggtttggt catagtaacc
     9481 aacctcaaca ttagcgccaa agcgtttttc tcccttgata aacggaattt gatccacgat
     9541 tgatttgata aaggttgatt ttccgatacc attgggacca acgatagcga cagcattcat
     9601 cttacgaaga tctaggttga taggttgtga caagacttcc ccgtcataac caatagcagt
     9661 attttcaaca gtcaaaacaa cattgcccga cgttttttca gactggaagg tcatgttggc
     9721 tgctttcttg ccagcttcag gcttgtccaa acgctccatt ttttctagtt gtttacggcg
     9781 agattgagca cgtttagtcg ttgaagcacg aactagattg cgattgacaa agtcttccag
     9841 agcagcgatt tccttctgtt gcttttcata gttttttgcc tcagtagcta gcttttgctc
     9901 cttcaattcg acaaaacgag agtaattccc cacatagcga tccaaggaat gcttggtcaa
     9961 atctagcgta attgtcgcaa ccttgtccaa gaaataacgg tcgtggctga cgataaggag
    10021 ggcaccgcta tagtttacca agtaattctc tagccaggcg atggtttcaa tatccaagtg
    10081 gttagttggc tcgtccaaga ccaagagatt gggcttttca aggagcattt tggcaagtgc
    10141 caaacgagta ttttgaccac cagaaagctc agcaattttc atctgccaca tagactcgtc
    10201 aaacttgaat ccattcaaaa tcgctcgaat atcagcttca taggtaaagc cacctgcttg
    10261 gcgaaaattc tcagataagc ggtcataatc tgacatcagt ttatccaaat cctcaccaga
    10321 cttttcaccc atctccagct ccatctgacg cagttgtctc tccgtccgac gcaaatcatt
    10381 aaagacatga agcatttcat cgtagatggt attttcagac tcaaaacggc tatcttgggc
    10441 taggtaagac agagaaatat cttttttctt attgatttct ccgctagttg gctcctcttc
    10501 tccaactaaa atcttcaaaa gagtagactt acctgcacca tttttcccaa caagagcaat
    10561 ccgatctcgt tcatcaacct gcaggttgat attatcgaaa agaacctctc ctgcaaaaga
    10621 acgttcaatt ttattagctt gtaaaataat catacaagta gtatagcatg tttccctaag
    10681 gcattcaaga taatcgtaag tcttttagta caacttttat aacataaaat aaactaaatt
    10741 atgtatattt tatattagat tccttcacta tcttgttgga ttttctaacc agctaatctt
    10801 gtttcaaata gttatcgcac aagtctatta tttaattctt ttcatcattt acgtacgtat
    10861 agcagattga aataagatga gaacaaatcg attgggaaag taaaattaat ttctataaat
    10921 gttttagcaa ttgtttcgta ctattttaga ttcagtctac tatatacaat attttcggaa
    10981 cattcaactt tttaactcta tttattacta gatttcataa ttaaaaagcc tactgaccaa
    11041 gctagaaagc ttgatacaat aggcttttta aagactgatt atttaacagc gtctttaaga
    11101 gctttaccag ctttgaatgc tggtacttta gaagctgcaa ttgtcatttc tttaccagtt
    11161 tgtgggttgc gacctttacg ttctgcgcgc tcacgaactt caaagttacc aaaaccgatc
    11221 aattgaactt tttcaccagc tgcaagatag tcagctactg ctgcaaatac agcttcaact
    11281 gctgctgctg agtctttctt agtcaattct gtagcttctg ctactttagc gatcaaatct
    11341 tgtttgtttg ccatgttaat gattcctcca aataatttct aattaacaaa tataatcata
    11401 tcctaaaatc ccttttaggt caagttaaaa acgctatttc ttcccatttt atttattttt
    11461 taggagtggt aacgtatcaa aatagcccaa gcgttctcac ccgtgtgagt ttgaataatg
    11521 gaacccgttt ccaaaacaga aattggcttt tcaacataag cttgtaagct ttctttcatc
    11581 tcttttgccc aatcatcact accagaatat gaaattccaa tctctgctac agcacgttca
    11641 gaaagcgatg ttatcaactc atctaaccat tttttaaatg ttttagttcc acgaccttta
    11701 accattggct gcaattcatg gtctttcatt tgcatgacag cacggatatt gagaagagag
    11761 ctcaacaagc cagttacacg gctaattcgt ccacctttga caagattttc caaagttgaa
    11821 acaccaatat aaagctctgt atggttttta acctcttcta catgagataa aattgcctcc
    11881 atatctttac cttcttgagc taacttcgca gcctcaacaa cttggaattt cagggcttgg
    11941 tcagtgaagg aactatcaac aacagtcaca tctgcagtag ataggctagc accttggcgt
    12001 gctgcttcta ccgtacccga aagagcatgg gacatatgaa tagcaagaat ctggccacca
    12061 tctttgcata ggtcttcaaa aatctcagca aagacaccta caggtggctg acttgttttc
    12121 ggaagattct tactttcttg catcaactga agaaatttac cttcttcttt caaatccgca
    12181 tcagaataaa caacattatc aatcattaca gataatggaa caattgtaat atctaattgc
    12241 tttactagtt caggttcaat agtaacagat gaatcggtta caatcttaat ttttgtcata
    12301 gtatcaatct ttctatttta ggattcagat tggtttcctt acttctaatt atatcaaaaa
    12361 aaagattaaa aatcctaatg gagtcaatca aattttccgt aaaatttgat ataatcaact
    12421 tataagaaaa gaggtgtcct atgattaaaa aaatttaccc catttttacc attttactag
    12481 gtgctgctat ttatgctttt ggactgactt attttgtagt tccccatcat ctctttgaag
    12541 gaggggcgac aggcattacc ctcatcacct tttatctttt taaaatccct gtttccctca
    12601 tgaacctgct gattaatatt ccccttttca tcctagcttg gaagattttt ggagccaaat
    12661 ccctctattc tagtttacta ggaaccttag ctttgtccgg ctggttagct ttttttgagc
    12721 atattcccct tcatattgat cttcaagatg atttactaat cacagccctt atagcgggaa
    12781 tcctattggg aattggcctt ggaattattt ttaatgctgg aggtacaact ggcggaactg
    12841 atattctagc tcgtattctc aacaaataca ctcatatatc cataggaaaa ctgctcttta
    12901 tcttagattt ttgtattctc atgttgattc tcctaatctt caaggatttg agattggttt
    12961 cctacacgct tttgtttgat tttattgttt ctcgtgttat tgatttgatt ggtgaaggag
    13021 gatatgccgg caaaggcttt atgattatca caaaacgtcc tgaccaactt gctaaggcga
    13081 ttaatgatga cctcggaaga ggtgttactt ttatttctgg tcaaggctac tatagtaaag
    13141 aaaatttgaa aatcatctac tgtattgtcg gaagaaatga aattgtgaaa acgaaggaaa
    13201 tgattcatcg aatcgatcct caagccttta taactattac agaagcccat gaaatcctag
    13261 gagaaggctt cacctttgaa aaagaataaa aagaggtaat gtcgtgacct caaaagttag
    13321 actaaatcat ctatcttttg ggttacagac aacctctttt ttattttatt tactcaagct
    13381 cttaagacca attccgagtt acttcttcat cagcctttaa ctgatccact aattggtcaa
    13441 ctgagtcaaa tttggtcata tcacgaatgc gatcaagcca ataaaccatg acggtttccc
    13501 cataaatatc ttgattaaaa tcaaaaatat tgacttcaaa acgtgcttct tctccatcaa
    13561 aggtcacatt tttcccgaca ctagccatag cacgatactt ctgtctttga atctcaacat
    13621 caacgacata aacgccatct gctggcatat aagtacggtc taaaagcact aaattcgctg
    13681 tcggataacc aattgtacga ccacgagcat taccatgaac caccatacct cttgatggaa
    13741 gcggtgcccc caaaagtttt cctgcttctt tcacatttcc atctaaaata gcttgacgga
    13801 tacgagttga actaatcttt cctttctcat cttctacagg tggaacaatg ataacttctc
    13861 catcaaagta atcctttaaa tcttctgctg tttttttgtc agaaccaaat gtataatcaa
    13921 aacctgcaac aataattttg gcattcatag ccttgatata agttgcaaaa aattcttgtg
    13981 cagtgagact agcgaattga ctactaaaat caaggagata taattcttct acaccttcgc
    14041 gctttaattt tctttcacgt tcagcagggt tcaaaatatg caaaaacaaa tctggatgat
    14101 aaggctctaa agcgatcttt ggagattcat taaaggtcat aacgacgata ggtaataaat
    14161 cctttctcgc agccttgttg gcaacacgaa ataattcttg atgcccctta tgtatgccat
    14221 caaaatagcc gagaacaacg actgaatcag atggtgtgcc aatatctttt tggtttttta
    14281 taggaatagt aataatcata aaataattat atcatagcga tagctatttc tggaacagaa
    14341 aatctgaaat gttgtttttt tcacatgaag tgtacctgtt ttcaaaaagc actttattct
    14401 atcgttgctt aactatgaac tttgcaatat tcttctcaaa aacttgtagg acatcttcaa
    14461 aattttgcaa ggagtgatta gacttgttcg gtaaccataa agtgtcatac tatgcttatg
    14521 tatgaaaaag caatgcaact aactcctgag aactttaaat tactaattgg tgccgaaaag
    14581 gtagaattta gaatcgaggt acacctatgg ctgtaaaatt tacaaaatga gacaacttgg
    14641 gcaagatgtt tgaagaattt cctaaactcc ctgatttgaa gcaagtcact ttccctgatg
    14701 acaaagaaaa aagccaaaac agcaaagaaa aactagatga ctgctttcca acaactccca
    14761 tctagtgtgc ttcagactgg gctatttttc tctccatctg ttagcttgga ttctcagaca
    14821 gtttcagcta aagaatatct tttcccttat cagaaggaac ggctcaaacc attcagacaa
    14881 gtgaagggac gacaagccaa tatttgaaac cagatagcag ttcttatagt caattgaaat
    14941 aaaatctgaa gaaatcgagt aggaaactca tatcaatttt taacagtgtt ctattccaga
    15001 ttcaatccac tatacatatt aaaaagtatg ggtaccaaaa caaaaaaaca ggctctccga
    15061 aaactcggaa agccttattt taagctgttt ctagcttcct cacctttaca tttcaaggtt
    15121 cgggataaaa ggttcaatgg acctttttat ttagcgattg ggtaaacaga aacttgtttt
    15181 ttatcgcgtc ctttacgttc aaagcgtact acgccttcaa ctttagcgaa caaagtatcg
    15241 tctccaccac gaccaacgtt tacacctgga tagatgtgtg taccacgttg acggtaaagg
    15301 attgatccac ctgttacagt ttgtccgtca gctgctttag ctccaagacg ttttgcttgt
    15361 gaatcacgtc cgtttgatgt agaacctcca ccttttttgt gggcgaaaag ttgcaagttg
    15421 ttaagagtca tttttaacat aatgttttcc tccgtgttag ttttctgtga taactctggt
    15481 ttggacgaac tcagaatagt tctccgataa gtttgccata cctaagaaaa atgattcaaa
    15541 gaataactgg gtcatttctc tctggtgtga aggaagatct tttggtattt caaccatcag
    15601 atagccacct tcatcttcgt ttaattctag gattggttca tagcctgcaa atttctcaat
    15661 agaattgata aagttaatgg caagcgtaga aaccgatgca cacacgacat ctaagccgta
    15721 ttcgccactc tcggcgtgtc cagtaatttc cgcactcctc agctcgccat cttcggctct
    15781 ctcaaagact gcctgtatca tgtgttctcc ttaaaattaa gcgttgattg cgttgatgac
    15841 aacttttgta tatggttgac ggtgaccttg tttacggtgg ctaccttttt taggtttgta
    15901 cttgtaagta accactttct tttgttttcc ttgtttttca acagttccaa ctacagtagc
    15961 tccagcaaca agtggagttc cgacaacagt attttcacca ccaacaagaa caacttcgtt
    16021 aaaagtaact tcttgaccag cttcaacgtt caatttttca acgtaaactg cttgaccaac
    16081 ttcaacttta acttgttttc cgccagtttt gataattgcg tatgtgctca ttatgcacct
    16141 cctatgattt ttatgggttt ccccgatttt ttgtgaagac tcgcctagca tcgtgggacg
    16201 aaccacttaa acttgaataa tcaagcaacg atgttcgtgc ggttgcacag gatcgtgcat
    16261 agtcaactct tcaagtatag catatctcct attttcttac aagtaataac acctaaaatc
    16321 aagctttttc ttttactttt ttctgccaag aggcaaaaag catgctgagg taaaaaacgc
    16381 tcatcataat aggaacacca agaatggtct tttcatgata gaaaatcgtc aaataggctg
    16441 aaaagacaac gccaaggaca aaactactaa gcaggctaac aaatatgaat ccttcacgca
    16501 aaaaaggagt gtgcttggtt cggaaataat ctccaaaagc cagcatggtc cgtttgatat
    16561 tccctgtcat aaaagcgtta ttataggcaa tacccgacac ttctccaaaa gcagttgtca
    16621 ccagtcccat acagaaggcc aagggcggca ctagatagat attatccaca gtttgcggca
    16681 caaaagcaat aatgattgat aagattgcca agggaatcaa ggacagaata ggttttttca
    16741 caattctcaa tttttcctta taaatcgtta ataaaaagac tcccatcata aacgctagca
    16801 aggtgagaac cttgtcccta acatccgaaa cattattttt aattaattct actgaaagaa
    16861 agacaacatt tccagtttgt ccagctacaa gggtattccc gcgaacaata aaagtgtaag
    16921 catccacata tccagcacaa aacgtcaaaa aaagtgctaa ccttttagac tgacgtgata
    16981 tttttcttat aggtaataac ctcattttcc ctcccattgt attttctctt agaaatattg
    17041 taccatttct ttctaaaaaa tcgtagacta ccatttagat tttactatta gcataaaaat
    17101 aataatagac aactatttat ccaaaaatag atagaggtaa catgtttgca aacaaagcat
    17161 acgaatcttt agtaaaatca tttccatgaa actagaatag agcccctctt agcaaaaatc
    17221 attattttaa tttatttcta atcactcctt gacataaata actctcacca ataaaagact
    17281 atgtcttaaa aaaatggtat aataaaatca atacttgggc ttgatggcta tgctactaat
    17341 aacaattagg agagaaaatc aggcacttgt taacaacaag gattatcccc ttgagatgaa
    17401 aggaacttta gaaatcttat gatgaacatg caaaacatga tgcgtcaagc acaaaaactt
    17461 caaaaacaaa tggaacaaag ccaagctgaa cttgctgcta tgcaatttgt tggcaaatct
    17521 gctcaagatc ttgtccaagc gaccttaact ggcgataaga aagttgtcag cattgatttc
    17581 aatccagctg tcgttgaccc agaggacctt gagactcttt ctgatatgac cgttcaagcc
    17641 atcaactctg ctcttgaaca aatcgatgaa actaccaaga aaaaactggg tgctttcgct
    17701 gggaaattac ctttctaaaa acaaggagct agaacaatgc ttgtcgataa caaaggctaa
    17761 gaaaggtgca aaaatgactc tataatattt gtagtgggta aatccactat agatattatg
    17821 gagcctattt tattgtagaa aacgcataat agcaggtgtc aagacactta atattatgcg
    17881 ttttctcatg aaaaaattct cttttcatac tcatttaaaa tcaaaaaggg aaattatcgt
    17941 tttacggaca tacatattac agatttctat aggtcgtgta tagacaggat atcatcgctt
    18001 ggaagttttc ctttttgaca ccaatcagta atttagttct caggaattaa tggcagtgct
    18061 tttcgtacat agtttcataa ctacagtata gcatagtata tcgctttata gttttcacta
    18121 ttgatgaact gcttgagctg ctgtgatgag ggtcaacttg taaacatcat ctgcattaca
    18181 tccacgagaa agatcattaa ctggcttgtt taaaccttgc aaaacaggtc ctacagccgc
    18241 aaagccaccc aggcgttcag ccatcttgta accgatattt cctgcctcga tacctgggaa
    18301 gatgaagaca tttgcttgac cagctaccgt acttccagga gctttcagag ctgcagtttc
    18361 aggaacaaag gctgcatcaa attgcaactc accatcgatt tcaaggtcag gacgcaagtc
    18421 gtgagcaatt ttagttgctt caacgacctt atcaacgctt tcaccaaacc ctgaaccttt
    18481 agtagaatag ctcaacatgg caattttagg ttcgatgcca aacatcttag ctgtgattgc
    18541 tgagttgatg gcaatttcag ccaaggcttc tgcatctgga ttgatgttaa tggcacagtc
    18601 tccaaatagg taacgttccg taccacgaac catgaggaag gctcctgaag tacgagttac
    18661 atttggacga gttttgatga tttgtagagc tggacgaact gttgaagctg ttgagtgaat
    18721 cgctcctgac accattccat caaccaagcc caagtaaacc aacatcacac caaagtagtt
    18781 gacatcttca accaaaacct tgcgtacatc ttcttcagtc attttgccct tgcgacgctc
    18841 caccaaggca gaaaccattt cttcaaattg aggataatgt tgagggtcga tgacctcata
    18901 accatccatg atcccttcaa tttcaagata aattttaatt ttttcaggat ttcctaacaa
    18961 aacaggaatc acttctgttt cttttaccaa acgtttagtc gcttgaagaa tacgtggctc
    19021 ttccccttca gggagaacga tacgagcatt tttaccaaca aggttggctt tgagactttc
    19081 aaaaacttcc atgagttttc tcctttaaga taataattat actctgagac agtttttata
    19141 gagtattagt tgataactgg gtaataaggt tactgaaatc atccggcaag ggactttcta
    19201 actgcaagtc ttgctctaaa aatggatgat aaaaggatag gtaatggcaa tgcagagcct
    19261 gacgttgaat accatcttcc agactaccac catacaaatc atctcccagc aaaggaaaac
    19321 cgatatgaga aaaatggact cggatttgat gggttcgacc agtgtgcagg tgaatataga
    19381 ccaagtgaat atttccataa gaagctacaa tcttgtatga agtatgggca tactttccgc
    19441 ctttagccac tcgtctggta ataatggaat cttcatcacg cgcaatcgga gcaataattt
    19501 ccccttctgg ctccaaatgt ccatctccct taaccaaagc aaagtagcgt ttctcgatag
    19561 atttcttctg caactgcttg tctaatcgtg catgggcata accgtgcttg gcaaagagca
    19621 tcaagccaga agtgtcccta tctagtctgg taacaatgtg aacctgctga ttttcataat
    19681 tttgcttgac atagtaaccc ttgataaaat tggcaatggt attagagtga ttaacactag
    19741 gaatagaagc cactccatag ggtttattca agactagaaa gtggtcatcc tcatagagaa
    19801 tatctaatgg aagctcaata gcctccaagg tttcaaagcc tttctcagcg ggaatgtcaa
    19861 tggtaacgta gtctccaacg tccaatagat acgttgcatt ttgcggttga ttattgacca
    19921 gaatagctcc acctcgaaac ttaatcttgg ccagcaatcc cttagaaacc tcgtgctttt
    19981 ttaagaaggt cttaaccttg acatgttcat ctgcgataaa ttcaaacctc attcatccac
    20041 ctcaccgata aaggcatcct taacacggtt ccagaaactg gtatggctag gagtcgcgac
    20101 aaagtgaatc ttatgatggg cgatttgata ctcaatacgc tcaatattac ggaaagaata
    20161 aacgctattg tcaaccgaaa tagtatgata atcgtttctt gttggaataa gttcaatctt
    20221 atccttctta ggcacaataa tggaagagcc cagtgttcga tagacacgat tattaaggct
    20281 ggcaatttcc gttaattgca aagcttcaat ggtagggtgt aaaacagcac cgccaagaga
    20341 cttgttatag gcagtactac cagtcggtgt cgaaactgtt agcccgtctc cacgaaaacg
    20401 ttcaaaggga acaccattta ttacaatatc tgccaccatg gttcgatcag acctgcggat
    20461 gctggcttcg ttgagtgctc tgaaaatctt aacttcacca ttttcaagaa agaccttcac
    20521 attcagaaca gggtaagaaa cccttgcccc agtatctagc tgcaaattag tcactagctt
    20581 gtccaactca aaatcacgat aatctgtata gaagcccaaa tgtccagtgt gaagaccgat
    20641 aaagcggacc ttctcaagct gattttcgta cttatgaaag gccgacaaga gcataccatc
    20701 cccgccaatg gaaatgacaa tatccggatt ggtatcattg agtataaact gatttctctt
    20761 caaacgatct cgcaattcat acaaaaccct ttgactctgc ggttttctat tggctatcag
    20821 atcaattcgt ttacctgtat tcttcatctg tatcgtcact gtttcctaca ccgtcattta
    20881 attttctact caaaggatca aaaagtgcct gggcttcttg gatatcatca cgaatttcac
    20941 ccatttcttc atccaactga tgggcgattc tagctgtaat ttccagtcgc ttcttaatct
    21001 catctgggaa atccccttgg tacttgtagt tgagagaatg ttctatcgtt gcccagaaat
    21061 tcatggccaa agtacgaatt tgaatttctg ccaaaatagt cttagctcca ttgatggtat
    21121 caaccgtata ttctactacc acatgatagg aacgatagcc tgatgctttt ctatgagtaa
    21181 tgtaatctcg ctcctgtatg attcgcatat cctgacgctt gtgcaaaata tccactactt
    21241 ccttgacgtc atctacaaac tgaaccatca cacgtaagcc agcaatatcc tgcaaatcgt
    21301 gttccaaggt cgcataagta atgccacgac gagccatttt ttctttgatg ctctcaattg
    21361 gcttgactcg accggtcaca aactcaattg gagaatgctt attttgctta cgatattgct
    21421 tacgaatacc acgaagttta atctttaact caccaacagc ttgaatgtaa ggatctagaa
    21481 attcttccca ttctaaggtc atatattctc ccttgttctc atattatccg tcaaaaatat
    21541 ctttgatttt ttctccagat tcatatacaa taaatacaat gcttattata ccataaatcc
    21601 gctttcaacg ataaaaaaag gtaagaaaaa tgaaacattt agaaattgaa ttgaaaacac
    21661 tattgaaaaa agatgaatac aatcgtctaa aagaccagtt cacaggtgtc actcctgttc
    21721 ttcaaacaaa ttactacatc gacacgcctg attttgaact gcgagaaaag aaagtcgcta
    21781 tgcgcattcg aacctttgaa gactgggctg agttgacact caaagtcccg cagagtgttg
    21841 gaaacatgga atacaaccaa aaattgcaac taaaagatgc tgagaactat ctgagtaagg
    21901 aagaacttcc tcaagggcta gtactggatg aattggcgaa acatggtatc caaagtaaga
    21961 actggcaggt tcttggttgt ctaacaacgc ttcgctatga aatgaaaaca gctattggtc
    22021 tcatggcact ggatcagagc cgatactttg atatgacaga ttacgaattg gagcttgaag
    22081 tggaaaatca tgagcaaggc aaacaggatt tccgacaatt tttagagaaa aatcagattt
    22141 cctaccaaaa agctccttca aaattggttc gatttgtcaa aagtatgaaa aatagctgaa
    22201 ataatctcca ttttttggta aaatagaaaa gataaaaata cacaaactcc agttcatata
    22261 tgtaaggtaa atataactag gatttataaa gtttacagag gacggtctat aatgtcagat
    22321 agaaaaaaca tgaaactttt cgcactcaac tctaaccaag agattgcaca gaaaattgcc
    22381 caagctgttg gtgtcccact tggaaaacta tcatcacgtc aattttcaga cggagaaatc
    22441 caagtaaata tcgaagaaag tgtccgtggt tatgatgttt acatcatcca atcaacaagt
    22501 ttccctgtca acaaccacct aatggaattg ttaatcatgg tcgatgcttg tgtgcgtgca
    22561 agtgcccaca gtatcaacgt tgtccttcca tattttggct atgcacgtca agaccgcatt
    22621 gcttgtcctc gtgagccact tacagcaaaa ctagttgcca atatgctggt taaggctgga
    22681 gttgatcgta tcctgactct tgatttgcat gccgttcagg ttcaaggttt ctttgatatt
    22741 ccagtggata atcttttcac tgttccccta ttcgcaaaac attactgcga taaaggattg
    22801 cttggttcag atgttgttgt cgttagccct aaaaattcag gtgtcaaacg tgcgcgtagc
    22861 ctggctgaat atcttgatgc tcctatcgcc attatcgact accctcaaga cgatgcaact
    22921 cgtaacgaag gttatattat tggtgatgtt gaaggtaaga aagctatctt gattgatgat
    22981 attttaaata caggacgtac cttctctgaa gcttctaaaa tcgttgaacg tgaaggagct
    23041 acagaaattt atgctgtttc tagccacggt ctcttcgtcg agggagctgc tgagcttctt
    23101 gacaatacta atattaaaga aattcttgtg actgattcag tagcaacaaa agaaaaaact
    23161 cctaaaaatg tatgctacat cactgctagt gagttaattg gtgatgctat cgtccgtatt
    23221 cacgaaagaa aaccagtcag cccactcttt gcctacaata aaaagaaata aggtgattct
    23281 ttgatttatt tggacaatgc tgcaacgact cctatgtcag cagttgctat ttcagctatg
    23341 accaaggtta tgcaagaaac ccacggaaat ccttctagta ttcatggtca tggtcgtcaa
    23401 gctggcaaac tcttgcgaga agcccgtcag gaactagccc agttactaag gacaaaacct
    23461 caacatatct ttttcacttc tggtgggact gaaggcaata atactaccat cattggctac
    23521 tgtcttcgtc accaagaaca aggaaaacat atcatcacaa ctgccatcga gcaccatgct
    23581 gtccttgaaa caattgatta cttggttcaa cactttgggt ttgaagcaac cattatccag
    23641 ccagaaaatc aagaaatcac agcccagcaa attcaaaagg ctttacgtga cgatacgatt
    23701 ttggtttcta ctatgtttgc caataatgag acaggaaacc tacttcccat cgctgaaatt
    23761 ggccaaatac tcaagcaaca ccctgctgcc tatcatgttg atgcagttca ggctattggt
    23821 aaaatcccaa ttcattcaga agaattgggc attgattttc tcactgcttc tgcccacaaa
    23881 ttccatggtc ctaagggaat cggttttctc tacgcatcta gcatggactt tgattcctat
    23941 ctacatggcg gagatcagga acagaaaaaa cgtgcaggaa ctgaaaatct gcctgccatc
    24001 gtaggcatgg ttgcagccct aaaagaagac ctagaaaaac aagaagaaca ttttcaacat
    24061 gtacaaaagc tagaaactgc ctttctggca gagctggagg gcattcagta ttacttgaat
    24121 agaggaaaac atcatctccc ttatgttctc aatattggat ttcctggtca gaaaaatgac
    24181 ctcttactcc ttcggctaga tttagctgga atttcaatct ctactggctc agcctgtact
    24241 gcaggcgttg tccaatccag ccatgttctt gaagccatgt atggcgcaaa ttcagaacgc
    24301 ttgaaggaat cccttcgcat cagtttgtcg ccacaaaata ccgttgaaga cctacaaacc
    24361 ctcgcaaaaa ccttaaaaga aattatcgga ggttagccat atggcatttg aaaaaatcat
    24421 tcagttaaaa aattgtcgtt acgattacac tcttagccct tctgttaaaa aattcaccct
    24481 caaagataac accttttttg aaactaaggt tggtaactat gaactgactc gccttttgga
    24541 aaaagtgcca aacagcggtg aaggcttcca actcaaaatc atcattaaca aggaacttac
    24601 aggggctaaa atcaatatca ctgacaagtt tggccttcgt ctagttgata ttttcaaatc
    24661 agaagaccac catattcatc aggaaaaatt ctacttcctc atggatagct tggtagaacg
    24721 tggtgtcttt acaaaatcgg aaagatagag ccaaaatgtt tgaactgacc tataaggact
    24781 gctatcatgt agagcgtact ctcaagtatg aggaacatga ggctctcatg ttgactttgt
    24841 caggatgtgt aaccttacca gatacacttt atgtgacttc tctgactttt aggggcaaaa
    24901 aagtttatca gggtctggtc ggagacctct accgttttct atctcatgca gattttttac
    24961 atcaaaacta agatttttct tagttttttc ttatttttgt tgattttttc acaatgtttc
    25021 tataaaatag aagaatagaa aggttgtgat tttgtgaaag ataaacagtt tgctattcca
    25081 aaagctacag caaaaagact ctctctctac tatcgaattt ttaagagatt tcatgcagaa
    25141 aagattgaac gtgccaactc taagcaaatt gcagaggcta tcggtattga ttcagcgacc
    25201 gtacgtcgtg atttttccta ttttggtgaa cttggtcgtc gtggttttgg ctatgatgtc
    25261 aaaaaactaa tgacattttt tgccgatttg ctcaatgaca actctattac caatgtcatg
    25321 ctggttggta ttggaaatat gggccatgcc cttctccact accgcttcca cgaacgtaac
    25381 aagatgaaga ttatcatggc ctttgaccta gacgaccatc ctgaagtcgg tacccaaact
    25441 cctgacggga ttcccattta cgggatttct cagatcaagg ataaaatcaa ggatgctgat
    25501 gtgaagactg ctatcctaac tgttcccagc gtcaagtcac aagaggttgc taatctcttg
    25561 gttgatgctg gtgtgaaagg aattctcagt ttttcaccag tccatctgca tttaccaaaa
    25621 gacgtggtcg ttcagtatgt cgatttgaca agtgaactcc aaaccctcct ctacttcatg
    25681 cgaaaagagg attagaaagc gaaaatcatt ttatgaaaaa accagttatt gggattacag
    25741 gaaacgaaaa aactcatcca gatgatgaca tcatgatgag ctacgcagca aaaggctttg
    25801 ttgaaggcgt taaagatgct ggagggattc ccatcatcct accgattggt gatcaagaaa
    25861 tggcctgcca ctatatcagt ttgattgaca agctcatctt gacaggtggg caaaatgtcg
    25921 atccaaaatt ctatggcgaa cccaaaacca ttgatagcga cgattatcac cttcaaagag
    25981 atatcttcga actggccctc atcaaggaag ctattaaaca gaaaaagccc attttctctg
    26041 tctgccgtgg tacccaactc tttaacgttg ccatgggtgg aactttgtac caagatatcg
    26101 aagaccattg gcaggattct tctgttgagt acacaactca acgcttggta acagaaccag
    26161 ataccgttct ccaagaaatc tatggagaaa tctctcatat caactccttc caccaccaga
    26221 gcatcaagga cttagcacca aatttaaaag ttgtggctca tgatcctaaa gatggtatca
    26281 ttgaggctgt catgagtacg gatgatgtcg cctttctcgg tgtccaatgg catccagaac
    26341 ttctttttga aaatcgtccc aaagataaaa aactctttga ctatgtcgtt aatgaacttt
    26401 agattaaatc tgtcttttca cgataactaa agtaattaga atgagagaca atcaaatggt
    26461 ccaagagaac aatccccatc aattcgcagg cttctttaac aagtttagtg acatgatcat
    26521 cattttggct aggcgctacc gctcctgaag gatgattgtg gaccaagata agagaagtcg
    26581 ccatatgctt gattgcatag tgaagaatct ctcgcggttc agcgatacta cgagttacag
    26641 aaccgataaa aatggtctgc tgatggatga tttgattttg agtattgaga tagagtgcca
    26701 ccaggtgctc ttgtttttta tcccctaatt cctgctgcat cttcttggcc aacttttgac
    26761 tgctgagaat actttccgtt tcaagagtct cgtgtttgtg aatacgatgc cccagttcaa
    26821 tcatagcttg taattctatg gccttaacac gcccaatacc agacaaactc tgcaattcct
    26881 gcagggtcat ttttttcaaa tccgttaggc ttgaaagatt gttcaagact ttttgggcaa
    26941 tttcaaaaac gctagcttga cgtgttcctg tcctgagtaa aatagctagc aactcttggt
    27001 tactaagcgc ttcaactcct tccttggcca gcctttctct tggtaatagt gaatcttctt
    27061 ggaatgaaat actgtacata aaaatcctcc tcactttatt attcgtgaga aggatggaaa
    27121 attagatttt tttctcaatt ggagccacac tggctaaaag ttttttcaaa cctacttctg
    27181 ggaaattgat tttcaattcc tgcctagcac cgctacctga aacttccaga acagttccct
    27241 ctccccattt cttgtggaga gcaatgtcac caatggacca atttgcctcg ctagatgctg
    27301 attttgcgcc agctgtaaat tgaccaaatg gaagaccgct tgactggatt gattttgggg
    27361 cagcaccgcg tttacggtct tgaagagcct gagccaaact cataccttga ccaaaggaaa
    27421 tactaccact gctatatgat gccttaaagc ttgtatttgc aggacgagcc agaccttgat
    27481 actcaagcaa gtctgaactg atttcgttaa taaaacgagt cggacggtta taattggtac
    27541 gaccaaaaag caagcgtgag ttggcattgg tcagatagag aattttctct gcacgcgtga
    27601 tacctacata ggctagacgg cgctcttctt ctaattcatc tggatcttca gtcgcacgac
    27661 taagtggaaa gacattttct tccatcccaa tcaaaaagac aactggaaat tcgagacctt
    27721 tggcagcatg cagggtcatc aaggtcactt ctgatgtctc ctgactacct gaatctgtgt
    27781 cagcaatcaa agccaagtca tttaagaaac gactcagttt gtccagacca gtttcctctt
    27841 ctgtcacatc agtggtgtca tcaaagttct tcgtaacaga aagaaactct tcgatatttt
    27901 caacccttgc cttgctttct agagtcgctt gggcgttaag aatatcgaca taacctgttt
    27961 tttctaggac ggactcaacc aactctgtaa tgcttaagtg gtctagctgc tcccgcaaat
    28021 caagcatcat attggcaaaa tcccagatag attgggctgc cttacccttg ataccagaca
    28081 acataatatt agcagaagca tccagcatag acatattttg caaatttgca aaatcacgga
    28141 ttttctcaac tgtacctaga ccaattccac gtttaggctc gttgataata cgctcaaaac
    28201 taatattgtc actcaaatta gcaataaggt tgagataagc aataatatcg cgaatttcct
    28261 tacggctgta gaatttggtt ccaccaacca tggtataagg aatgttagac ttgagcaggg
    28321 cttcctcaat tgtacgggac tgggcattag tccgatagag aactgcaaaa tccttatgaa
    28381 ggaagttttg actgcgacta agttcatcga tggttctgac tacaaataca gcctcatcca
    28441 gctcatcatc ggcacgatag taaacgattt gctccccatc agcgttttga gtccagagat
    28501 ttttaggacg gcgattttta ttatttttaa taacctcgtt ggccgcttgg agaatggttt
    28561 tggttgagcg gtaattttcc tccaacaaaa caaccttggc tttggggtaa tccttttcaa
    28621 agtccaagat attctgcata tcagcaccac gccaaccgta gatagactgg tccgcatccc
    28681 caaccacaca gatattttta aaacgggaag ccaagagttt gaccaattgg tactgagcgt
    28741 ggttggtatc ttggtactca tcaacgtgga tgtattggaa tttttgctgg tagtaggtca
    28801 aaacatcagg attttgatca aagagacgca aggtcagcat aatcaaatca tcaaagtcaa
    28861 cggattcaga ctgacgaagt tctttttgat aggttgtata acactgggcc acaatttgcg
    28921 tatacatatc gccagcttgg gcagcataag caacatcatc aatcaaatca ttcttagcat
    28981 tggaaatggt ccccaaaata gttcgttcat tccatttttt aggatccaag ttcaactgtt
    29041 tgagaatacg tttcatgagc gttcgctgtt caccaggatc cacaattgta aaattacgat
    29101 tgtagccaat atggtccgca tcgcgacgca aaatacgcac acacatggag tggaaggtcg
    29161 caatcagaca gtcctgagta gctggattga ggctataagc acgctctttc atctcacgcg
    29221 cagccttgtt ggtaaaggta atggccaaga tattccaagg attgaccagc ttttcatcaa
    29281 tcaaataagc gatacggtgg gttaaaacac gagtctttcc agaaccagcc cctgccatga
    29341 ttagcaaggg accttctgtc gtttgcaccg cctcagcctg acggtcattc attccattta
    29401 ataatgcgtt catcttctct tccttactct tgaagtcaat atttctatta tatcagaaat
    29461 cagggaaaat agaaacttta cggggagtag caaaatatag tggattgaaa ctagaatact
    29521 acactgtggg tttctaaaac actcgacttt tcactcaatt ttttcataaa ctagctcaat
    29581 acctcaatag acttcctgca aaactagaat cctagttcat gattgataat accagcaatc
    29641 aaattcattc gtaatccgaa gc
//
LOCUS       DAVDHC010000025        26454 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVDHC010000025 DAVDHC010000000
VERSION     DAVDHC010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26454
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.025"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..508)
                     /locus_tag="VUR43_001544"
     CDS             complement(<1..508)
                     /locus_tag="VUR43_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5413211.1"
                     /translation="MKKVKLGEVCEILSGYAFKSSQFNDNKIGLPLIRIRDVERGFSD
                     TYFEGTYPEEYLIKNGDLLITMDGSFILKKWEGDLALLNQRVCKIKITDKSVDEGYIS
                     WLIPKFLKEIEDKTPFVTVKHLSVAKIKDISFVLPNKLEQKLIAKKLNTISQIYDFRK
                     IQSEKFNEL"
     gene            complement(521..2014)
                     /locus_tag="VUR43_001545"
     CDS             complement(521..2014)
                     /locus_tag="VUR43_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET5413212.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            complement(2522..3688)
                     /locus_tag="VUR43_001546"
     CDS             complement(2522..3688)
                     /locus_tag="VUR43_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET5413213.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLKTEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFLASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(3701..4440)
                     /locus_tag="VUR43_001547"
                     /pseudo
     CDS             complement(3701..4440)
                     /locus_tag="VUR43_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            complement(4462..5286)
                     /locus_tag="VUR43_001548"
     CDS             complement(4462..5286)
                     /locus_tag="VUR43_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5413214.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISHMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(5422..6636)
                     /gene="thiI"
                     /locus_tag="VUR43_001549"
     CDS             complement(5422..6636)
                     /gene="thiI"
                     /locus_tag="VUR43_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET5413215.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYAQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(6645..7787)
                     /locus_tag="VUR43_001550"
     CDS             complement(6645..7787)
                     /locus_tag="VUR43_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET5413216.1"
                     /translation="MIYFDNSATTKPYPEALETYVQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            7925..8359
                     /locus_tag="VUR43_001551"
     CDS             7925..8359
                     /locus_tag="VUR43_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413217.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            complement(8404..10629)
                     /locus_tag="VUR43_001552"
     CDS             complement(8404..10629)
                     /locus_tag="VUR43_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET5413218.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(10793..12745)
                     /locus_tag="VUR43_001553"
     CDS             complement(10793..12745)
                     /locus_tag="VUR43_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5413219.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(12742..13653)
                     /gene="pfkB"
                     /locus_tag="VUR43_001554"
     CDS             complement(12742..13653)
                     /gene="pfkB"
                     /locus_tag="VUR43_001554"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET5413220.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGACFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(13650..14390)
                     /locus_tag="VUR43_001555"
     CDS             complement(13650..14390)
                     /locus_tag="VUR43_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5413221.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            14552..14639
                     /locus_tag="VUR43_001556"
     tRNA            14552..14639
                     /locus_tag="VUR43_001556"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14586..14588,aa:Ser,seq:gga)
     gene            complement(14822..15169)
                     /gene="ssrA"
                     /locus_tag="VUR43_001557"
     tmRNA           complement(14822..15169)
                     /gene="ssrA"
                     /locus_tag="VUR43_001557"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(15703..16812)
                     /locus_tag="VUR43_001558"
     CDS             complement(15703..16812)
                     /locus_tag="VUR43_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET5413222.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            16915..18156
                     /locus_tag="VUR43_001559"
     CDS             16915..18156
                     /locus_tag="VUR43_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET5413223.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKNLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(18387..19799)
                     /gene="sufB"
                     /locus_tag="VUR43_001560"
     CDS             complement(18387..19799)
                     /gene="sufB"
                     /locus_tag="VUR43_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET5413224.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(19853..20293)
                     /locus_tag="VUR43_001561"
     CDS             complement(19853..20293)
                     /locus_tag="VUR43_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET5413225.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDVVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAVFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(20280..21506)
                     /locus_tag="VUR43_001562"
     CDS             complement(20280..21506)
                     /locus_tag="VUR43_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET5413226.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(21517..22779)
                     /gene="sufD"
                     /locus_tag="VUR43_001563"
     CDS             complement(21517..22779)
                     /gene="sufD"
                     /locus_tag="VUR43_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET5413227.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKVTAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(22807..23577)
                     /gene="sufC"
                     /locus_tag="VUR43_001564"
     CDS             complement(22807..23577)
                     /gene="sufC"
                     /locus_tag="VUR43_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET5413228.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(23727..23921)
                     /locus_tag="VUR43_001565"
     CDS             complement(23727..23921)
                     /locus_tag="VUR43_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET5413229.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(23949..25604)
                     /gene="dnaX"
                     /locus_tag="VUR43_001566"
     CDS             complement(23949..25604)
                     /gene="dnaX"
                     /locus_tag="VUR43_001566"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET5413230.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSTLDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(25604..26101)
                     /locus_tag="VUR43_001567"
     CDS             complement(25604..26101)
                     /locus_tag="VUR43_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET5413231.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            26295..>26454
                     /locus_tag="VUR43_001568"
     CDS             26295..>26454
                     /locus_tag="VUR43_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5413232.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKY"
BASE COUNT         7919 a         5800 c         4853 g         7882 t
ORIGIN      
        1 cgagctcgtt aaatttttct gattgaattt tacgaaaatc ataaatttga cttatcgtat
       61 ttagtttttt tgcaattagc ttttgttcta gtttattagg caatacaaat gagatatctt
      121 ttattttagc tactgaaaga tgtttcactg taacaaaagg ggtcttatct tcaatttctt
      181 ttaaaaattt aggaatcaac caagatatat aaccttcatc tacactttta tccgtaattt
      241 taattttaca gacacgttga ttaagtagcg ctaaatcccc ctcccatttt ttcaatataa
      301 aactgccatc cattgtaatc aataagtctc catttttaat aagatattct tcgggataag
      361 ttccttcaaa gtaggtatca gaaaaacctc tttctacatc tcgaattcgt attaagggga
      421 gaccaatttt gttatcatta aattgtgatg atttaaaagc gtaaccagat aaaatctcac
      481 aaacttcccc caacttcact tttttcatac agccacctcc ctacttgagt aatttttcca
      541 attcagccaa gccagcttga atttcttttt ctaaatcatt gattttcttt aatatgactt
      601 ctgttggttc atactcaact ttttcatact caatctcttt atatttattg atagacaaat
      661 cataatcatt ttcctttatc tcagcaactg gaacaaagaa agattgatcc gttctctgac
      721 gttctgcttc tttttcaaga tgatgaaagc gttcgataat atctggaata tcattgtcgc
      781 taatcggttg tcgcttatca tccaaactta aaccatccgc tttcatatcg taaaaccaga
      841 ctttgtcagt accaccatta ccagtttttg taaagatgag aatagcagtt gaaactccag
      901 cataaggctt gaacacacca ctaggcattg agattacagc atcaagctta tgattctcta
      961 caatttcctg acgaattcct ttatgagctt tagacgaacc aaaaaggaca ccatcaggta
     1021 cgataactgc tgctcgtcca cctggtttta aagttcgcaa gaaaagagaa agaaagagta
     1081 attctgtttt tttggttttt acggttgcaa gaaggtcatt agaggttgaa ttgtagtcaa
     1141 gtgagccctt aaaaggagga tttgctaaaa ccaaagtata tttatcggct tcttcattat
     1201 cttgagacag cgagtcaagg taactgattt gtggattttc tactccatgt agcatcatgt
     1261 tcatcgcccc aagtctcaac atagtcgtat ccgtatcatt tccatgaaac atctgattat
     1321 gaaaatgatt gatattatct gtattggttt cccattcatc tttcttacgc tttaagtaac
     1381 ggctagcaga tactaagaag ccagcagaac ccatagcggg atctgagatg atatctttga
     1441 tagtcggttg catcaactca accatcatat cgatgatgtg acgaggtgta cggaactgtc
     1501 catttttacc tgcggtcgac aattttgata acagatattc atagatatct ccgatatcag
     1561 taatactttg tttgtcatta tcaaaatcta catctaatcc cctagttgga aaaacatcta
     1621 agatagaaat tgccttttga agcgtagcag gtttatttat ttgaaaaata gcttctcgca
     1681 tatatcgtga aaaggctgta tcatctgtat cccccttgag atttttaata aacggaaaaa
     1741 tctcctgagt cattaaacga taaacttcct gagcatctcc tatattttta aaagttgacc
     1801 aacggtattc aggtttatct tttggaaaaa ctccctcata aggaatccct agaaattcag
     1861 catcactttc acgtccaagc tcgacactat ccaaatcttt cataaataag agataagtca
     1921 actgttcaat atttgttaaa ggatttgcgt ttccttctgt ccaaagaatt tcccacagct
     1981 ggtcgatttt attttttaat tcgcctgtaa tcatatcttc ccttttcttt agtttttaaa
     2041 acttagtaat atcattattt tatcagattt caaacaaagc ttcaattaac tatatctatg
     2101 cgtcacctga atattttata ctcttcgaaa atctcttcaa accacgtcag cttcaccttg
     2161 ccgtaggtat atgatactga ctctgtcagt tctatccaca acctcaaaac agtgttttga
     2221 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatt aatagactgg
     2281 tttggtatcc tgaaaactat atcgtatagg tgtcgtcatg gatcctttta gctgatttaa
     2341 ggatacgaaa acacaatact atgactaaat tgaaatgtta aaattcaatt tctagccacc
     2401 taatcctgct tcaaatagtt atcgaacaag ttttatgata gctaccttgt taggatgctc
     2461 ttatttttta ccagacaaaa caaaaggatt aagggagtga atttccttaa tccgatagtt
     2521 cttattcttg acgttgtccg aaatcagcaa tcatctgatc catttcttgt cgactcggag
     2581 ttgtcagcat atacaggtaa tctccttgaa gttccgcgaa ggcagctggc atgacttttt
     2641 taaccttgaa ctgctggcta tatttggcaa gcaaatcctc ttctgaataa acatagtgag
     2701 catttgcacg gcgagaagta gccaaacaat actgagtttc aaagtctgac gccaggaact
     2761 cctctcctgc gacaatagct gcatagccac gataaaggtc caaggaatga gcaaagttat
     2821 aaacatcaat ggtaaaacca cctgcagggc ggttattgta ctcgatggta atataatcgt
     2881 ccccctcacg gaagaactca atatggaaaa accgttcttt cataccaaat tctttgacaa
     2941 ttgcttcccc atacttgcgc agtttaggat ccatatcctt gagcacataa taagaattgt
     3001 ccatcttata aatcatgagg tcaagcggtg tataggcgta gtcaaaggtt gttgagaaga
     3061 caatctttcc atccttgtcc acgagcccgt caaaggtaca gatttcgctg gaagtgacaa
     3121 atttttcaaa gaaataaagg gttgaatggt cccattcttg cttgaagtga ttgatatcgt
     3181 cttctgtctt aagtttaaag gttgcggctg ctcccactcc attatcaggt ttggcaatca
     3241 ttggaagacc gatttctttc actgcttgat caacatctgc ttccgtcttg ataacagctc
     3301 caggtaccac aggaacacct gcttttttga aaagtttctt catttcagac ttatatttcg
     3361 tctttttgag atcctctggt ttggcaccaa aaacattgaa ttgttctctg agtgttgcgt
     3421 ctagctcaag ccagtattca ttgtgagact cgatgcggtc aattggacca tgtttataaa
     3481 agagaaaagc aactgcacgt ttgacttcat ctatgttctc aagattatca acacgaaaat
     3541 actcggtcaa gctattgcgc aagggctcat ccaattgctc gtaagactct tgaccaattc
     3601 ccaagactgt gatgccttta ttagctagtt cgatggtaaa ctgttgaaag ttttgtggat
     3661 agtagggaga aataacaagg taattcatag gtaactcctt ttataaatag agattaccga
     3721 ggaaataagg catttgttta cgccaccatt cccagtcatg ggcgacatca tgtccccatt
     3781 cagcaaacca ggctggaatt tgtttcttgt caaaggcttc tttgagcttg taaaaggatg
     3841 gcaaaccatc ttgttcccag gctccaagcc ccgtacacag cacaatctct gcctgacggt
     3901 aacggtcaat aaaccagccg tcgttttggt tccaaatata atctactggc gagttttggt
     3961 aaatagcatc atcgttgtag taatcaccga caaagaaacg tgcgtcgtaa acaccactga
     4021 gagcaatcac tttggtaaag acatctggat gctggaggaa gaaattgagt gcatgatagg
     4081 ctcccataga gcaacctgtc gtcatcatgc catcaaacca acctgtcttg tgcttgataa
     4141 aagaatggcc tcctcaatca cataacattc gtaggcacgg tgcatttccg cttggtcatg
     4201 agcatttttc caagtagcca accagctctc actatccaca ctagataggg taaagaactg
     4261 gacaaggcct tcctcgataa aggaagcaca ggcatcaatc atgccaaaat catagtattc
     4321 gttgtgacta ccacctgatg aagcaaagac cacaactgga atcccaccat gtccataacg
     4381 gttaaggtac atttcacggt taggatgacc actccagtgg ctaagatgtt caatatgcat
     4441 ttcgtttttt cctttcttaa cttaccattt ttctgcaaaa aatctcagac aatctggtag
     4501 attttctgac caagggattt cactatggat ggcaccagac tgaactttta gcacaagatt
     4561 atccagatgt actccccctg ctatcaaatc atggtaatag caaagcgacg agtcgatata
     4621 ggcttgtttg atattgccat ccatcaaggt cttgtctgta tcatctgctt cttctgttcc
     4681 tacatagatg aagatgcgct ggtcaggcga tagtttctgg cactcgatat agcggttaaa
     4741 ggcttcttgg tggagccagt ttgcagatga aaaaacgccc aagcaaccaa tttggtcttg
     4801 gtattccaaa ccgataaact gggtaatatt gcctcctagt gaggaaccaa tcatagccgt
     4861 atgctggcag tctgcttttg tacgataggt ctcatcgata aaaggcttga ccacctccat
     4921 gacaaactca gcatactcca cacccttacc accaaactgc tgctctggga taggagattc
     4981 ttggaacttc caagccgcat actcattcat tcgccccata ccatcattgt caatagcaac
     5041 gacaatcatg tgactgatat ccggatttcg tttgatagct gggataatct tccatgaata
     5101 tccaatgaaa gactctttgc tataaaaaac attttgcccg tcatgaaagt atacaacagg
     5161 ataggaacgg tctgtatctt tctcataatc tttaggaaga agaatacgta cacggcgctc
     5221 cttacctgta taaggaacct tgagtttgtg ttctttcatt tttagataaa agtaggattg
     5281 attcattgtc agaaaactct ctatattcaa aattttatat cattatatca tgaaaataga
     5341 aaaaagttag ttttttacct gtttttagaa aaaaaactaa ctttttttac tgattttcgc
     5401 tattcttttg gattttctga attagagtag attatcaatc aagtcatcaa cttcatcttt
     5461 ttcggcttga ggtgtgattt cagtaatcat gattccagcc actgctcgct caaccaagcc
     5521 ttcaacatcc atacgcgctt cgtactgctc cgcattctta attttaggat ttgtttttgg
     5581 acgatctggt gcaaaaatgg tacaacagtc ttcaaacggt tggattgaaa tgtcaaaggt
     5641 atcgatttcc tgggcgatgt caatgatttc caacttgtcc atggtaacca caggacgaat
     5701 gatgggagtg ttggtaacag cattgatagc cttcatactt tcaagggttt ggctggctac
     5761 ttgacctaga ctttccccat tgatgataac caaaccattt cgtacctcac gaatacggtc
     5821 agtaatccgc atcataaagc gacgagttag agtcatcaaa taagcttctg gcgctttggc
     5881 tttgatttcc tcttgaatct ctgtgaaagg cacctcgata aactggatat ttccgccaaa
     5941 cttggtcaat ttacgggtca agtcctgcgc tttcttgagg gcaccaggac tagtatatgg
     6001 tggactagca aagtgaactg cctcgatatc caccccacgc ttaagagcaa gataacctgc
     6061 tacaggtgag tcaatccctc ctgacaacat gagcatccct ttacctgaag ttccaactgg
     6121 caaaccacca gccccacgaa tggtttcata agaaagatag gctgcttctt cacgaatctc
     6181 cacctgaaga ttgatgtcag gacttttcat ttgaacttgc acatttggaa tggcttcgaa
     6241 tacagcccct ccaagtgttt ggttgagttc acgactatca agttcaaagt tgtggtcgct
     6301 acgcttgcta gaaatcttaa aggtcatacc ttccttgtag atgtcccgca taatctcttg
     6361 gacagaagac ttcaaaactt ctacagattt ttcaacctta taaacaggag aaaagttttg
     6421 aattccaaaa acttgtttga gagattctgc aactgctgtg taatcagctc cattgaggta
     6481 agcgtgggca cggtcgcgat ctgctgttac cttaacttgg gcatagatag acaaaacgtc
     6541 cgaaatatta ttacgaagtt tattgatgaa acgcatacgg tttttaccct tggttgacaa
     6601 ctctccgtag cgaatcataa tttctgaata ctgcatgaat gctcctatct tacttttcta
     6661 gtttgattgt aaatcaattt taacttggtc aaaaactgct cgacctgact catatcattt
     6721 tccaagtcta ggctaagacg cacagctgac ttggccttat ctttgtccac tcccatggca
     6781 atcaaggtac cggctggttt tcctgcctta gatgaacaag ctgaggttgt tgagatgaaa
     6841 atatcatagt cttcaaaggc gtgaacgatg acttcacctc gaacaccttt gattccaaaa
     6901 gtcagaatat gaggtgcaaa gtcttcctca tctgaaaaga caaaaatatc cggatagttc
     6961 agaagagctt ggtgaatcac tgccttcatc tgcccagtct tgctcctaaa gatatctagc
     7021 ttttccatag ataaacggag agccttggct gtcgctgcaa tccctgccac attttcagtt
     7081 gtcgaacgat aatctcgctc ctggccacca cctgtaagaa gaggtgtaat cttcttgcca
     7141 gatttgatat agacaaagcc aacaccacgg acaccatgaa atttatgact cgagaaggtc
     7201 gcgcaatcca cccgttctgt cagatacttt tcagtcggaa ttttggcaag cgcctgaacc
     7261 gcatcaacgt ggaaggaaat agtcggcttg tctgccaaga attctgaaat agcctcaata
     7321 ggttggatag agccgatttc attgttcaca gccatgatgg aaacgaggat tgtatcaggc
     7381 cgtatcaaac ctgctaacgc ctcaacatcg accaagcctt tcttatcaac tggagcaaaa
     7441 tccacttcaa atccttgact tttcaaccag agggctgact ctttgactgc tggatgttca
     7501 atggctgaaa caatgatgtg cttgccaaac tgagcttttt caaaggccac acccttgata
     7561 acccagttat ccccttctgt tccaccagag gtaaagaaga tttcatcgct tttcttaccg
     7621 attaaatctg caatctgttg gcgagaagca tctaagattc gtgttgcttg gtctcccaaa
     7681 cgatggagac tagatgggtt tcctaaaatt tttgaagcga cctgcacata ggtttcaagg
     7741 gcttcaggat aaggcttggt cgtcgctgaa ttatcaaagt aaatcatgtt tctcacgctt
     7801 tctaaaatca ctccctctat tgtatcatga aacggagctt gcgacaagaa agggcaattt
     7861 ctcttttttt aagatttttt taaagaaaca gagtataata agtcataatc aaaggagaga
     7921 atgtatgtct aattatcgta gaacttcaaa accaaaaaca gaacacatca aaaaaggctt
     7981 tacagtcttt caaaaaaccg ttgcgactat cgctagtatc cttggcttga ttaccgctag
     8041 tatcacgatt atgaacgcct tggataataa caaaaatact aaaaaggaac ctacaacaag
     8101 ccagacgaca acaattgtca aagaaattca aaaggaatcc cctcaggaaa atactagtcc
     8161 caataaggaa aataagactt ctcaagaaaa aacacaacaa gaagaaacgc caaaatccag
     8221 cgtcaaggaa gagaaaaaag aagagcagaa aacatcaact caggattctt ctactcctgc
     8281 tcctactcca agtaaacctg ctactgaaaa cgaaaaacag tccaataccc caacttcgga
     8341 aaataaaact aatcaataat cactaaaata gcctccttcc aaacttggaa agaagctatt
     8401 tttttattgt tgtaaaactt ttcttggttt ggtaccttca gctggaccaa tgacacctgc
     8461 catctcaagc tcttccatga gacgggtcgc acggttaaat ccaactgaca aacgacgctg
     8521 aatcatggat gcactggctt tctgtgtttc gataaccaaa gacttagctt cttcaaaaag
     8581 cggatcacca ccagcatctc catccgaaaa ttctccttca ttttcagaaa cctcacctgg
     8641 atcaaaactc tcatcgtagt ctgcatctgc ctgagtcttg atgaagttca caatgcgctc
     8701 aacatcgtca tccgagataa aggagccttg gagacgaact ggatgatttt catcaatcgg
     8761 tttaaagagc atgtctcctc gaccaagaag tttttctgct ccattttcat ccaaaatcgt
     8821 acgggagtct gttcctgatg aaaccgcaaa tgctacacga gatggaacat tggccttaat
     8881 caaaccagag atgacatcaa cagatggacg ctgagttgca agaatcatgt ggatacctgc
     8941 agcacgcgcc ttctgcccaa gacggatgat agcatcttcc acttccttgc tggccaccat
     9001 catgaggtca gccaactcat ccacaatcac gacaatgaat ggtagcggaa tttgcttgta
     9061 ctcagactgg gaattgaact cttctacctt ggcattaaaa cctgcaatat tccgaactcc
     9121 caccttggca aagagttcat aacggttttc catttcatcc acaacctttt gcagagcctt
     9181 gctggcttta cgtggattgg tcacgactgg aatcaagagg tggggaatat cattgtaaac
     9241 agataactca accatcttgg gatcgaccat cataaattta acttgatctg gtctcgcctt
     9301 catgagaatg ctagcaataa tgccgttaac tgctactgac ttccctgaac ccgttgaacc
     9361 tgcaactagc aagtggggca ttttagaaag gtcaaaagct cttgcggttc cattaacagc
     9421 cttccctaaa ggaatttcca agaaattttc tgctttcgtt tgcgattgtt cccatagttc
     9481 tcggaaagat acagtggcaa tatcggagtt gggcacttca attccgatta gggatttccc
     9541 agggattggt gcttcaatcc ggacatcttt ggcagccaag gctagagcga ggtcatctga
     9601 tagattggaa atgcggttga cccttacacc aacagccggc ttgacttcat acttggtcac
     9661 tgatggccca atttcggccc gttcaactgt taccttaata ccaaagctag caaaggttgc
     9721 ttctaagatt ttgatatttt ctctgacaat tttcttctct ttagactgat cttttggttt
     9781 atctggtgca aagagttgta agcttggaag tttgtattca agggcttctt tggctgaaaa
     9841 atcgacctga acatcttggt catctgagtc atcttcctgt tcagggaatt taagttcagc
     9901 ttgaggcagg atgatttctg gttccaccca cttttcttct ggaataggtg gaagattttg
     9961 aacagcttcc tctgtcagaa tttcacccgt ttccatatca acaggaggca aatcgagtaa
    10021 ggctttttca gtctcttctt gttctaatct agcctctttc tcagcctttt ggcgagcttt
    10081 ttcttcttgt ttgacaaagc gttcctcttt tcgacgctcg tgcccttccc accatttggc
    10141 aaagcctcta ctgaaaaatt cagcaatatc gtaaacagac caagggctga ctaggagaga
    10201 acccactaaa atcaagatag aaccaataaa gtaagttccg atatttgaaa agagaaaggc
    10261 tgttggaata taaagagcga ccccgatcaa gccccctcca gcaaagctag tcgttcgaaa
    10321 accagtcaga tctgtcacaa cctgagccat ggtccctttt agaacggact tgtccaaacc
    10381 atatttccaa actaagtagg cctcaaaaat caagagtaag ccagcaaata tggtgaaaaa
    10441 gccagataag agtccttcct gttttcgtat ccacttgaaa aagaagagat agattaatag
    10501 gccgaatatc gccagataag ctaggctacc cactagcaag cgaattaaat tataaagggt
    10561 tatacctgca gcccctaatt tgaaggctgc gaaaatcaat aaaatcgcaa ttcctaatga
    10621 aatcaacatt cgttgaatcg cttcttttct ttccagttct gctttagacg gtctccgtct
    10681 tgttgtactt gtattcttgt ttgccattct tctattatac catatttcac aggcatttcg
    10741 ggaagagaaa aagactgcac caaacggtcc aatcttttca tttttctatt ttttatgctt
    10801 gtggtttgcg taggtaacca taaaccacac cacttacgat tgctcctacc aagacagaaa
    10861 cgaggtaaag gagagcattt gaagtaaggg cgataacgaa gattcctccg tgtggcgcca
    10921 tgagtttgat accagtaaga ccaacgagtc cacctgctac tgctgaacca aggatgaagc
    10981 ttggaatcgc acgagctggg tcagcggcac caaatggaat cgctccctca gtgataaatg
    11041 acaagcccat gatgatgttt gtcaaaccag agttacgttc ttccttagta aatttatctt
    11101 tgaaaagaag agttgcgaca aagattgcaa gtggtggcac cattcctcca gccataactg
    11161 ctgccatggc tacagaacca cctgaagaaa cagttgctgc aagcgtacct gtaccaaaga
    11221 cataagctgc tttattaact ggtccaccca tgtcaacagc catcattcca ccaaggacga
    11281 taccaagaag gacagctgaa cctcctccaa gaccgcctag gaagtcattc atagcagtgt
    11341 tgattgcagc cattgggata ttcacagcta gcataacaaa tcctgtcaag attgttccaa
    11401 gaagtggcaa tagaaggatt gatttagcac cttcgagtga acgaggaact ttaacgtatt
    11461 tcttgatggc aagaaccaag gcacctgcga taaatccacc aacaagggca cctaggaaac
    11521 cagatgagac acctgcaaga gttgaagttg cttcaccacc tgcggcataa ggaattttac
    11581 caaaggcaaa accttctttg gcaatagcac cagccacgaa acctgctacc aaacccggtt
    11641 tttcagcaat agagtaggca acataacccg caaagactgg aagcatcaaa ccaaaggcag
    11701 ctccaccaat tttcatgaac atagaagcta actcatggta agaaccaaga ttgccaaggt
    11761 tttcatttgg aacacccaaa gcaccgtcaa tcaagaaggc aagggcaatc atgataccac
    11821 caccgataac gaatggtaac atttgagata caccactcat caagtgtttg tagaaggcac
    11881 caccaaggct ttgtttttcg ttagaggctg ttgcagcttt ggcaccatta gcggcacggt
    11941 agacttcagt atctcctgaa agagccaagt taattagctc ttctgtctta cggataccgt
    12001 cagcaactgg acgattgatc aatggttttc catcaaatcg atccatttca acggccttgt
    12061 ctgctgcaat gataatagct ttagccttac ggatatcttc tgcagttagt tgatttccaa
    12121 caccgctagc accgttggtt tcgaccttga taccaacccc catttcagca gctacttttt
    12181 gaagggcttc ttgggccatg taagtgtggg caatacctgt tgtacaagct gtaacagcta
    12241 cgataaagtc accagagtca ttagcaggtg cttgaacaag ttcctcagtt ttttctgaag
    12301 cttggtcaaa aagttcgata acttggtctg cagatgttgc ttgacgaagt ttgtctgcaa
    12361 aaccgtcttt catcaagtat tgagacaatt ctgccaaggc tgccaagtga gtatcattgg
    12421 caccttctgg agctgcaatc atgaagaaga ggtcagttgc ttgtccatcc aagctctcgt
    12481 agtcaacacc cttatttgac ttagcaaata gaactgtcgc ttctttgaca gcagcgtttt
    12541 tgctgtgagg cattgcgatt ccatcaccca aaccagtaga agtcaaagct tcacgcgcca
    12601 aaattccttc tttaaatgtt tcaaaatctg ttacataacc gtgctctgtc aaatttttaa
    12661 tcatctcgtc gatgacagct gttttttcag ttgcctgcaa atctagcaac atgacatctt
    12721 ttctcaatag gtcttgaatt ttcatctttt ttctacctca acttttccat atgtttcttt
    12781 aataaattcc gccgttgcca agtcatctga gaaggtagtt gccgttccgc aagccactcc
    12841 ccatttgaag gcttctacta cgtcttttga tttgacaaat tcacctgtga atccagcaac
    12901 catagaatca ccagctccaa ctgaattttt gactgttcct ttgattggtt tagcgaagca
    12961 agctccctca gatgtgacaa gaagggcacc atcaccagcc atagagataa taacattttg
    13021 agcaccctta gccagtaact cacgagcgta tttctcaatt tcatctaaac tttcgagttt
    13081 aaccccaaaa atcgctccaa gttcatgatt gtttggtttt acaagaagag gctggtagtc
    13141 caaactatca attaaggtct gtccttcaaa gtcacagacc acttgcgcac cagtctggcg
    13201 cgtcaaggaa atcaaatcct tatagataac attgcctaga tttttagcac ttgaacctgc
    13261 aaagacaact gtatcttctg ctgtcagact agataaaata gctttcaatt cttctagctg
    13321 aaccgattca acagttggac ccgttccgtt gatttctgtt tcttggtctg ctttgatttt
    13381 aacattgata cgagtatctt ctgccacctg gacaaaacgt gtctcgattt cttcctctgc
    13441 taaagtatct gtgataaatt taccagtaaa gccaccgata aatcccgtcg ctgtatttgg
    13501 tatattcaaa cgtttcaaga cacggctgac attgattcct ttcccaccag caaacttatc
    13561 atcactgtcc atacgattta cactaccaac tttgacttgg tccaaacgaa cgatatagtc
    13621 aatggatgga ttgagtgtga ctgtataaat catacttcta ttacctccgt tttctcctta
    13681 ataacctgca agagctcatg cccttgacta gtgataacga tagcgcgttt gagtggtgct
    13741 accttggcaa agcaagtttg tccaattttt gacgaatcca ccaagacgta ggtctgcttg
    13801 gcattctcca aaatagctct tttcacagct ccctcctcca tatcaggagt cgtataatag
    13861 ccatcgtcaa caccattcat tccgataaag gcacggtcaa agtgcaattg gttaatctgg
    13921 ttaagagcaa cgcccccgat actagcatct gtcgccgtct tgacgtttcc tccaaccatg
    13981 acagttggaa tctgcttttc aaccaactga gcggcatggt gaatggagtt ggtcacaact
    14041 gtaacattct tattgaccaa ttcatgaatc aaaaaagcag ttgttgttcc agcatcgata
    14101 aagatgacat ctttttcttt aatgagagag gctgctttct gagccagcaa cttcttttct
    14161 tgaaggtttt tgacagattt ttcttgaatg gtttcttcct cctgtaagga gtgggggagt
    14221 tctgctccac catgcacacg acgaagcttg ttttccgctt ccaactcatc caagtctctt
    14281 cgaaccgttg attctgacgt ttctagcaaa ctaactaatt tttctagaga aactacatga
    14341 tgctgattta actcctctaa aattagttgt ttacgttctg tttttaacac tgaatcacct
    14401 cctgttatcg tttacactat tcattctatc atactttctt tcgaagtcaa gcatttttta
    14461 tcattttctt tcaaaatcta tcatttttct tatttctaga atttttattg caagataaga
    14521 gcctttatgg tagactattt gagtaagtat tggaagatta ctcaagaggc ttaagaggcc
    14581 gtgttggaaa cgcggtaggc gtgtaatagc gtgcgtgggt tcgaatccca tgtcttccgt
    14641 cgaaaaaaga ttatttttag gatgcgacaa atgttgtatc cttttttcta tccttttttt
    14701 aaaatagggt ctgtttgtga ctcccttttt agcaaaagaa tgcaaaggaa taccaaagat
    14761 aaaaataaaa aacgttgatt taacaacgtt ttaccaagga atgcaaaaga atgcaaagga
    14821 ataatggagc cggtgggagt cgaacccacg tccaaacacc tgccaacata tttgtctaca
    14881 accataggtt atgtattatt ttaacagccc ctcgacacat aactcaagtc tagaaactgc
    14941 gagtctatca atctcttatc aagccgctag acaaggctta atcgtatctc gctaataata
    15001 agacctgtca ttgaacacga gcaatccaaa tcgggtcacg cctgctggtt tttaggcagc
    15061 tagagcgtaa gaagtgttat tttttgcagt tatatttaac tgagcgttta cgtcgccaca
    15121 cgagtcgcaa aatatgcctc ataatgcctg tcgaatccgt aacgacccca aaagacaata
    15181 aaaccattat accttatcta actcaaaaat gcaaaaagaa atcacatacc taagatgaag
    15241 ctatctgttt tgaagaaatt cacgaagaga attattctaa aatactttca gatgagaatt
    15301 ttcgtactct ctttatttca attcatttga gtttaaaaac tataaaatca atccttatat
    15361 tattcggact acttttcact tattgcacca aaatatagta aaatgaaata agaataggac
    15421 gaatagatca ggacagtcaa atcgatttct aacaatgttt tagaattaga ggtgtactat
    15481 tctagtttca atatactata aataagtttc attcgaactt taatagacta tgaaaaccag
    15541 tggaacttac cctgacacgg aattccactg gttttttcga tttttatcag attaacttct
    15601 actattctta gctgtgaaaa ttagtttaag actttaactt attttcagtc ttctaatcta
    15661 aaggccactt ccagtaaaga aaaatcaggg ttctcctgac ttttacttag ctaattctct
    15721 ttctcgttct ttcattattt tatgattttc atacaaacgg gataagaact tagaaatttc
    15781 tttcaagata gaataggttg gcactgcgac aatcattcca actacaccat agatattgct
    15841 tgacaacaaa agtaaaacta aaatcgtgat tggatgaacc ttcataacac ttcctacaat
    15901 tcgaggatat aagatattgc catctacctg ctgaacaaca agcatataaa tcactgcaat
    15961 cagcagtcta tggggatcag tgaatatatt tgcgatgatc ataggaatca aaccaatact
    16021 tggccccaca taaggaatta aattggctac accagaaaaa atggcaaaaa ctaaagcata
    16081 ttttaaacca ataatactat agccaatata agccaaacaa cctataatga ttgcgtcaat
    16141 cgaaactcca ctaatatagc gagcaatcgt cgcatttaaa ttctttaata agcctgcaat
    16201 atgcaagcga tccctcttta gaatcgttct ttcaagcatg ggcaagaatt tatgtccatc
    16261 taataagaaa taaaccaaaa aaactggagt cataatcaaa atcaaaacag tactgataag
    16321 agctgacaag acgctcccca cactatttga tacgctattt aggatatttt gaagaatatc
    16381 aacataggat aagtttaact gctgaattgt agcttctaca tccaaattct ggagcgcagg
    16441 ataattagat aagtctatga ttaagtcttg tactcgacta taaatagttt gactagatat
    16501 aatcaaacta gataactgat taatcaaaat aggtaagaga tagacaacac ctatgaccat
    16561 tccccagacc aaagtacaca aggtaattaa aataccaagc aaacgattga gtttacagac
    16621 tttatttaag aaagtaacaa tagggtttgt caaataataa agaaagcccc ctaataaaaa
    16681 tggaatcata attgtattaa gcacgctaac aaaagggtta atcaaagatc ccatctgtct
    16741 ccataggtaa aagatgatgg ttaagagtaa aatttctgtg gtccaaaaaa ataatttatt
    16801 tctacgaaac atgagttacc tccctcactt tattttacca tattttcaaa aagcttaaca
    16861 gatgaattat taaagcaaga atattttttt tctttatgat agaataagac tactatgaaa
    16921 aaaatatttt taactttgtt aactgtctct cttttagggg gtgcttctac tgctgttgct
    16981 caagatttta ccattgccgc taaacatgcg attgctgttg aggcaaatac tggtaaaatt
    17041 ctctatgaga aggatgcaac gcaacctgtc gaaattgctt ccataacaaa attgattact
    17101 gtttatctag tctatgaagc tttggaaaac ggaagtatta ccctctccac tcctgtagat
    17161 atttctgatt atccttatca attgacgaca aattctgaag ccagtaatat tcctatggag
    17221 gcccgtaatt atactgtcga agagttgctt gaagcaactc tggtatctag tgccaacagc
    17281 gccgctattg ccctagctga gaaaattgct ggctcagaaa aagatttcgt cgatatgatg
    17341 cgggcaaaac tcttggaatg gggaattcag gatgccactg ttgtcaatac gacaggtctt
    17401 aacaatgaaa ctctagggga taacatttac ccaggttcta aaaaagatga ggaaaataag
    17461 cttagtgctt atgatgtcgc tatcgttgct cgcaacctca tcaaaaaata cccacaagtc
    17521 ttagaaatca ccaaaaaacc ttcttctact tttgctggga tgacaatcac ttcaaccaac
    17581 tacatgttag aaggtatgcc tgcttaccgt ggtggttttg atgggctaaa aacaggaaca
    17641 acagataagg ctggagagtc ttttgttggt actactgtcg aaaaaggcat gagagtcatc
    17701 acagttgttt taaatgcaga tcatcaagac aataatcctt acgctcgatt tacagctaca
    17761 tcttccctaa tggattatat ttcttctaca tttacacttc gcaaaatcgt tcaacaaggc
    17821 gatgcctatc aagatagcaa agcccctgta caagatggaa aagaagatac agtaactgca
    17881 gtggctccag aggatatcta tctaatagaa cgtgttggga atcaatcttc ccaatctgtt
    17941 caattcacac ctgattccaa agcaatccca gcaccacttg aagctggaac agtggttggc
    18001 catttgactt atgaagacaa gaacttgatt ggtcaaggtt acatcaccac agagcgccct
    18061 agtttcgaaa tggtagcaga caagaaaatt gaaaaagcct tcttcttaaa agtttggtgg
    18121 aatcagtttg tccgctttgt taacgagaaa ttataaaaaa tcgcgatttt aaaccgcgat
    18181 tttttgatac aagttcatct tcaaaatcct tgattttgag taaatctaat actcaaaatc
    18241 aaagaacaaa ctaggaagct agccgcaggt tgctcaaaac actgttttga ggttgtagat
    18301 gaaactgacg aagtcagtaa ccatacatac ggtaaggcga tgctgacgtg gtttgaagag
    18361 attttcgaag agtataaaat caaattttat ccaactgatc cctccatttc atagctaatc
    18421 aagcggttca gctcaactgc gtattccatt ggaagttctt ttgtaaaggg ttctacaaat
    18481 cccatgacaa tcatttcagt tgcctcagat tctgacaatc cacggctcat gagataatac
    18541 aattgctctt ctgaaatctt agatactttg gcttcgtgtt ccaaagccac ttgcgagttg
    18601 tgaatttcat taaatggaat agtatctgat gctgacaagt catccatgat aatggtatca
    18661 cattcaatgt gggaaacaga tttcttagag ttcttgttaa aggtgacttg tccacggtag
    18721 tcaacctttc ctccaccttt agcgatggat ttagacacaa tagacgagct ggtatgtgga
    18781 gcattgtgaa tcatcttagc acccgtgtct tggtgttgcc ctgcattagc aaaggcgata
    18841 gagagcatgg taccacgcgc tccttctcca tcaagataaa cagatggata tttcatagtc
    18901 gttttggcac ccaagtttcc atcaatccac tcaacagtgg catccttttg agccttagca
    18961 cgctttgtta ccaagttata gacgttatca gaccagtttt ggatagttgt ataacgcata
    19021 taagctccgt ccaaagcaaa aatttctaca atggcagcgt gcaagctatt gcttgaatat
    19081 gttggtgctg tacatccttc tacgtagtgg acgcttgctc cctcatcaac gataatcaag
    19141 gtacgttcga actgacctat attttcgtta ttgatacgga aataagtttg aagtggaata
    19201 tctaccttga caccttttgg cacgtagata aaagttccac ccgaccatac tgctgagttg
    19261 agggctgcca acttgttatc tgtcggcggt accaacttcg caaagtattg tttaaataag
    19321 tctgggtatt ccttgagtgc ggaatctgta tctgtaaaga taatacctaa tttttggaac
    19381 tcttccttca tgttgtggta aaccacttct gactcgtact gggcagaagc ccctgctaga
    19441 taagcacgtt cagcttctgg aatcccgata cgttcaaagg tttctttaat cttttcaggt
    19501 acatcatccc aagaacgggc tggtttgtca gatggttttt ggtagtagat taagtcatca
    19561 aagtcaatct ctgacaagtc tgctccccaa gtttgcatgg gcattttttt gaaggtttca
    19621 taagacttca aacggaactc caacatccac tcaggctcac ccttagcagc agataattca
    19681 cgaataacac cttcgttgag tccttttcct gtcgataaga caggctctac atcgtcatgg
    19741 aaaccaaatt tatattcacc aaggtcaatt ggttttggtt ctactctttc ttcagccata
    19801 atatcctttc tttcttcatt tctaataatt tataagacaa aagaaacttg tcttactgtt
    19861 tttcttgatt ttcaattgtt ttcttaaggg cattccaagc tagggttgca cacttgattc
    19921 tttgagggaa tttggcaaca cctgacaaga ataccgcgtc tccaagttgg tcttgacgct
    19981 catctttttg cccttgaacc atttcagaaa aaatagtcgc cagttctaaa atttcttgtt
    20041 tggtttttcc taaaacgaca tctgtcatca tactagcaga agcagttgaa atcgtgcatc
    20101 ctgaatttag aaaagcaata tcttccaaac ggtcctctgc atcaaacttg acagagaggt
    20161 tgatgacatc cccacaagtc ggattgttga gactgatttg ctcagcgtct tctaacttcc
    20221 cttggtgatg tggatttttc gaatggtctg ctaccactgc catataaagg ctatctagtt
    20281 tagaaagtgc cattgaaaaa ctcctttgtc ttttgtaggg catcgactag tttgtcgcaa
    20341 tctgccttgg tattgtagat ataaaaactt gcacgagctg ttgctgggac ttccaaatac
    20401 tgaagcaagg gttgcgcaca atggtgacca gcacgaacag ccactccttc ataatccaga
    20461 gccgtcgcaa gatcgtgagg atggagatca cctaggttaa aggcaataac acccgaacgt
    20521 tgagccaaat cctgagaacc gtaaatggtc aatccctcaa ttgcctgcag ttttggatag
    20581 acgtacgcaa tcaattcctg ttcatgagct tcaacggcat ccataccaat cttttccaga
    20641 taatcaactg cagtcgcaag tccaatagct cctgccatat ttggcgttcc agcctcaaat
    20701 ttccaaggca attccttcca actagcaaat tgctcgtaga caaaatcaat catctcgccg
    20761 ccaaattcta ctggagacat ttgctcaaga tacttttctt tgccgtaaag gacaccgata
    20821 ccagtcggac cagccatctt gtgacccgaa aaggcgaaaa agtccagatc caagtcctgg
    20881 acatcaatct tcatatgagg tgtagattga gcaccatcca ctaccataat tgccccaact
    20941 tggtgggcta attgagtgat ttccttgatc ggattgacca caccaagaac attggaggca
    21001 tgagctaggg aaacaaattt aaccttatca gtcaatttag ctcgcaaatc ctccatatcc
    21061 aaggcaccgt ctttaagata gacatagaca agctctgctc cagtctttcg acaagcttcc
    21121 tgccatggaa tgatattaga atggtgttcc attactgaaa tcaagacctg gtctccctca
    21181 gcgagaattt cctcagcaaa gcgtgccacc cagttaaggc tggttgtcgt tcctctggta
    21241 aagagaactt cctttgtaga gcctgcatta ataaacttac gaatggtttc acgagcagct
    21301 tcataagaag ctgtcgctcg ttccgctaag gtatggacac cacggtgaac attggcattg
    21361 tcctgctcat agtagctgtt aatagctttc agaactacta gtggtttttg tgtcgtcgca
    21421 gcattgtcca gatagaccag aggttcatca ttgacaatct gatctaaaat tggaaaatcc
    21481 ttgcgaatcg cttctacatc taacataggc ttccccttag cgttttgaca atttctcttc
    21541 gatagttgca atcatttcat cacgaacttc cttgactgga atctccacga taacagatcc
    21601 aaggaaacca cgaacaacca aacgctctgc agttacctta tccaatccac gactcatgag
    21661 gtaatacatg tcttctggat ctacctgacc aatagaggct gcatggcctg cagttacgtc
    21721 attttcatca atcaaaagaa ttgggttagc atctgaacgc gcttggtctg aaagcataag
    21781 aacacggctc tcttgttgcg catctgctcc cttagcaccc ttgatgatgt ggccgatacc
    21841 attgaaagtc aaagttgctt tttcaaggat aaccccatgt tgtagaatgt ttccgattga
    21901 gttgcagcca tagttagtta cacgagtatc aatcccttgt acctgacgac cacttgaaag
    21961 agctacaacc ttgaggtcag catggctacc attaccaatc aagtcactat caaaatcagc
    22021 aacgacattt ccttcgttca tgacaccgat agcccagtca atacttgcat cgttgcctaa
    22081 tttaccacga cggctaatgt aggcagtgac gttttcacct agacggtcga tagcagcaaa
    22141 cttgacttgc gcaccagaac gtgcaatcac ttccactgtg atattggcag ttgctttgtc
    22201 acttccttca ccgcgtgact ctaaacgctc cagataacta atcttagaat ttttaccagc
    22261 gataatcata atatgcttgt taaacggcac attgctatcg ctatcttggt agaaaattcc
    22321 ttcaattggc tctgtaattt ctacgttatc tggaatatag agtacagcac cactgttaaa
    22381 gtaagctgtg tggtaagccg ccaacttgtc atcatcatac ttaacagatg acatgaagaa
    22441 ttcttcgatc agctctggaa tttcttctaa agctgagtga aagtctgtga agacaacacc
    22501 ctgttcagct aactcaactg gagtttgttc gaaaacagtt tgagttccta cttgcaccaa
    22561 cttcaagtga tgatctaaag ctgtgaaatc tggaacattt gctgatggct cattttctgt
    22621 aatcgttcca tcacccagat tccaacggtg gaatttgaca cgctcaataa ctggtaattc
    22681 caaagtctca atcttgtcaa aagctttttg acggagatca gccaaccagc ttggttcagc
    22741 gtgcatttct gaaaaaagtt taatattttc tctagtcatt tacttctcct aaaagatacg
    22801 agggaattac aattcttcct tgtagtcgta gccaagttct tcagctaatt ttgcgtatcc
    22861 ttcacgttcc aaacgcgcag ccaattctgg accaccagaa aggacaacac gaccttccat
    22921 catcacgtgt accacatcag gtgtgatata gttcaaaaga cgttggtagt gagtgatgat
    22981 catagcacca aaaccttcac cacgcatggc attgacacct ttagacacaa ctttaagagc
    23041 gtcaatatca agacctgagt caatctcgtc caaaagagca aatgttggct ccaacatcaa
    23101 aagttgaaga atttcattgc gttttttctc accaccagag aagccttcgt tgaggtaacg
    23161 ctctgccatt tcttctttca tgttaagcaa ttccattttt tcatctagct tagtaataaa
    23221 ctcacgaact gaaatcttct catcatcttc tttacccgca ttcatagcgg cacgaagaaa
    23281 ctcagcattg gtaattccag ggatttctga tgggtattgc atagcaagga aaagtcccat
    23341 acgcgcacgc tcatccactt ccaactcaag gatgtttacg ccatcaaaca aaacttcacc
    23401 tttagttact tcatagtttg gatttcccat gatagcggca gaaagagtcg atttacctgt
    23461 accatttggt cccatgatag cggcaatttc tcctgttttc agggtcaggt taaccccttt
    23521 taaaatttct tttccttcaa tctcaacgtg aagatctttg atctctatta ctgacatgat
    23581 agttcctttc tttttcaaaa cttttacagt acttactaga aaaacgtctg atttccccag
    23641 aaatagagca aaaattctat aaatatactt ttctagtata acaaaaaaaa gcctaaaagg
    23701 ctttgatttt gtctggaagc tgagggctag tctttcctat taaaatgctg atcgatgaca
    23761 tcaacgattt tacccatcac ataactgact cggaaatttc taaagagtaa aattgcccaa
    23821 aaggctgcca taatatagcg gccagtcatc caggcttcat tgaaaaaata ggtctcagca
    23881 gctgtaaata gcgccataat aataaattgt tgtttattca taaacttatt gtatcatgaa
    23941 atctttcttt agtcttcctc taccttcact ttatcagcca aaaattcaaa tccttctgga
    24001 atcaggcttt cttctacttc tttttcagtt tgagaagatt tggctttggc tgaaaaggct
    24061 gcgcgaactt ctttccattc ctccatggaa atagctaaaa tctcaggtga aaaacctgcc
    24121 gcctgactga ggatattacc aaacatggta ttgagattgt ctcgtttcat agtttgacca
    24181 gcattgaagt tagactcaaa agcaagaata gcatggtgtt cattggcagc aaccggttga
    24241 gaaccaacta gcagagcctt gtccggccca cctagacttt caattacctc tccccaggca
    24301 ttctgcaaac gaattagatt ttgacgtgct aaatcaggat tttcgacggc ctcttgtaag
    24361 atagattgca ctttattgcg atcgacacga tagactgttt tgcccgtagc tggtcgacta
    24421 ggagctggtg caacttgttt aggaaccgca cctgcattag aaagctcttg tttgagacgg
    24481 gcaacttcct gtctcagcgt agcaatttca ttttcaaccg ctcctgatag agctggttcg
    24541 ggcttgattt ccgccaaacg gacggtcatc atttcagcat aaatcttggg ctgcaaacta
    24601 gacttaatat ctgctaaact cactgttgct aagcgaatca tttcaaacag atttttttga
    24661 ggaagtgcca aattttctac aaagactgaa ctatgatgag tattttctcc ccctgtttga
    24721 acaattaaca agtctcttaa atagtgcaaa agatcggtca caaaacgagt catgctctta
    24781 ccattgtcaa aaagaagatt caagcaagac aaagctttgg gaacatcctg ttgagacaag
    24841 gccgccacat aatcatccaa ggttgatagg ctaatggtgc cagtaatttc ttcagagata
    24901 gcagtcgtca gctcatttcc ctgtgtcaaa ctcagggctt gatccaaaat agacaaggcg
    24961 tcccgcattc caccttccgc ccgtctggca atgatttcca cagcctctgg ttcagaactg
    25021 atattttctt tttctaagat atagtgaata tgttccttaa tatcctgtgt cttaattgat
    25081 ttaaactcaa aacgttgcac acgggataga atagtagcag gaatcttgtg caattcagta
    25141 gtggccaaaa taaagactac attctgtgtt ggttcttcca gcgtctttag gagggcatta
    25201 aaagcccctg tagacagcat gtgaacctca tctatgatat aaaccttata acgagcaagg
    25261 ctaggcgcat aggtagattt atcacgaatt tcgcgaattt catctacccc attattagaa
    25321 gctgcatcca tttcaatgac atcttctaaa ctaccgtccg tcactgcttg acaaatatag
    25381 cagttattgc aaggttcgcc acccacttga ttgggacagt tcatagcctt ggcaaagatt
    25441 ttagcaacac tggtttttcc cgttccacga ggaccagaaa aaagataagc gtgacttatt
    25501 ttctcttgct ccaccgcttg tttaagagtc ttagccacaa cttcttgacc aactaactgg
    25561 gagaagtttt gacttctata ttttcgataa agtgcttgat acattaagat ttttcctcaa
    25621 acatcgtaaa gtcccatgtt gtcttttcaa gcaaaatagc gacaaattgt tccaaataat
    25681 ctcgatccat agcatcgtaa tcctcaatct ctgaagaatc cagatccaga actccaagta
    25741 actgaccatt cttcatcatc ggcaccacaa tttcactttt agctagacta tcacaagaaa
    25801 tatagttgag ataggtcgtc acatctccaa caataacagt ttcctgaaag tgagctgcct
    25861 caccacaaac acccttgcct agtgcaatac ggatgcagga aacacctcct tggaagggac
    25921 ctaaaaccaa ttcctttcca tcgaacaaat aaaagcctgc aaatacggta ttaggaaaac
    25981 gtgattttat gagagcactg gcgttggaaa gattagccaa aacattggtt tcgccttcca
    26041 ataggaagga caattcttca tttaacattt gataacgtga ttgtttttct gattttaaca
    26101 tagaactatt atatcaaaaa aggagcagag acaaaagaaa aatcccttgt ttagtaaaca
    26161 aaggattttg ggctctataa tatttgtagt gggtaaatcc cttatagata ttatggagcc
    26221 tatttttgtg tagaaaaaaa gtcccatatg acctataatg aaaagcgaca aaacaactca
    26281 ttagaaagat tcatatggaa caattacatt ttatcacaaa actgctcgat attaaagacc
    26341 caaacatcaa gattctagat atcatcaata tggataccca caaagaaatt atcgctaagc
    26401 tggattatga ggctccatct tgccctgatt gtggaagtct aatgaagaaa tatg
//
LOCUS       DAVDHC010000026        25579 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVDHC010000026 DAVDHC010000000
VERSION     DAVDHC010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25579
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.026"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            22..1866
                     /gene="uvrC"
                     /locus_tag="VUR43_001569"
     CDS             22..1866
                     /gene="uvrC"
                     /locus_tag="VUR43_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET5413233.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            1856..2689
                     /locus_tag="VUR43_001570"
     CDS             1856..2689
                     /locus_tag="VUR43_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET5413234.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(2871..3671)
                     /locus_tag="VUR43_001571"
     CDS             complement(2871..3671)
                     /locus_tag="VUR43_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5413235.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            3842..4447
                     /locus_tag="VUR43_001572"
     CDS             3842..4447
                     /locus_tag="VUR43_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET5413236.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYSEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            4460..5860
                     /gene="pepV"
                     /locus_tag="VUR43_001573"
     CDS             4460..5860
                     /gene="pepV"
                     /locus_tag="VUR43_001573"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET5413237.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            5914..6492
                     /locus_tag="VUR43_001574"
     CDS             5914..6492
                     /locus_tag="VUR43_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET5413238.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            6652..6804
                     /locus_tag="VUR43_001575"
     CDS             6652..6804
                     /locus_tag="VUR43_001575"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5413239.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGARNLPLSQ
                     LADSYD"
     gene            6847..6939
                     /locus_tag="VUR43_001576"
     CDS             6847..6939
                     /locus_tag="VUR43_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET5413240.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLVFEEL"
     gene            7110..8435
                     /gene="brnQ"
                     /locus_tag="VUR43_001577"
     CDS             7110..8435
                     /gene="brnQ"
                     /locus_tag="VUR43_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET5413241.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVMVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            8533..9570
                     /locus_tag="VUR43_001578"
     CDS             8533..9570
                     /locus_tag="VUR43_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET5413242.1"
                     /translation="MNQTVKYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEEHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVSNEKETRALGIEVG
                     DFISFDPRTVVTEAGFIKSRHLDDKVSAAILLNLLLIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDGQQTDEYTVSICVKDASGPYHYDFRQHLVTLA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYIKSALVD"
     gene            9572..10042
                     /locus_tag="VUR43_001579"
     CDS             9572..10042
                     /locus_tag="VUR43_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET5413243.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLEKETRLRFLEEMSLVQEAVAKAFTAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETCQAKSDEIKQLVKRLSSELDKLLEIKE"
     gene            10045..10761
                     /locus_tag="VUR43_001580"
     CDS             10045..10761
                     /locus_tag="VUR43_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET5413244.1"
                     /translation="MKKRYLVLTALLTLSLAACSQEKAKNEDGEAKTEQTAKTDGTVG
                     SKSQGTAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AESGLSLEEYYGFEGGDYVD"
     gene            11025..11450
                     /gene="rplK"
                     /locus_tag="VUR43_001581"
     CDS             11025..11450
                     /gene="rplK"
                     /locus_tag="VUR43_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET5413245.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            11658..12347
                     /gene="rplA"
                     /locus_tag="VUR43_001582"
     CDS             11658..12347
                     /gene="rplA"
                     /locus_tag="VUR43_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET5413246.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            12725..12862
                     /locus_tag="VUR43_001583"
                     /pseudo
     CDS             12725..12862
                     /locus_tag="VUR43_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(12993..13139)
                     /locus_tag="VUR43_001584"
     CDS             complement(12993..13139)
                     /locus_tag="VUR43_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413247.1"
                     /translation="MKTKEQTRKLASGCSKHCFEVVDRTDEVSNHTHGKATLTWFEEI
                     FEEY"
     gene            13153..13515
                     /locus_tag="VUR43_001585"
     CDS             13153..13515
                     /locus_tag="VUR43_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET5413248.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKTISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            14560..15552
                     /locus_tag="VUR43_001586"
     CDS             14560..15552
                     /locus_tag="VUR43_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5413249.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            15554..16372
                     /locus_tag="VUR43_001587"
     CDS             15554..16372
                     /locus_tag="VUR43_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET5413250.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            16374..17159
                     /locus_tag="VUR43_001588"
     CDS             16374..17159
                     /locus_tag="VUR43_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5413251.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            17198..17476
                     /locus_tag="VUR43_001589"
     CDS             17198..17476
                     /locus_tag="VUR43_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET5413252.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            17461..17658
                     /locus_tag="VUR43_001590"
     CDS             17461..17658
                     /locus_tag="VUR43_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5413253.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFLQLWNPQNPCQILIKKLE"
     gene            18190..24609
                     /locus_tag="VUR43_001591"
     CDS             18190..24609
                     /locus_tag="VUR43_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET5413254.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHEDIHSAMETSQDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAESTSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHF
                     IRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLF
                     NIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGT
                     DLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATK
                     YDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKSEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSNLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYINGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
     gene            25236..>25579
                     /locus_tag="VUR43_001592"
     CDS             25236..>25579
                     /locus_tag="VUR43_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5413255.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIIN"
BASE COUNT         8233 a         4442 c         5472 g         7432 t
ORIGIN      
        1 tttttttgct ataatggaac tatgaacaac ttgattaaat caaaactaga gctcttgccg
       61 accagccctg gttgctacat tcataaggat aaaaatggca ccattatcta tgtaggaaag
      121 gctaaaaatc tgcgtaatcg agtacggtcc tattttcgtg gaagtcatga taccaagaca
      181 gaggctctgg tgtctgaaat tgtggatttt gaatttattg ttacggagtc taatattgag
      241 gcacttctcc tagaaatcaa cctgatcaag gaaaacaagc ccaagtacaa tatcatgctc
      301 aaggatgaca agtcctatcc tttcatcaaa atcaccaatg agcgctatcc acgcttgatt
      361 atcactcgtc aggtcaaaaa ggacggaggt ctttattttg gaccttatcc cgatgtgggg
      421 gcagccaatg aaatcaagcg gttgctggat cggatattcc cttttcgtaa gtgtaccaac
      481 ccgccctcta aggtctgttt ttattaccat atcggccagt gtatggctca caccatctgt
      541 aagaaggatg aggcttattt caagtctatg gcccaggagg tttctgattt tctgaaaggg
      601 caggataaca aaatcattga tgagctaaag ggcaaaatgg cagcggcagc ccagactatg
      661 gagtttgaac gtgcggcgga ataccgtgac ctgattcagg ctattggaac gcttcgaacc
      721 aagcaacggg tcatggctaa ggatctccaa aatcgcgatg tctttggcta ctatgtggat
      781 aagggctgga tgtgtgtgca ggttttcttt gttcgtcagg gcaagctcat cgagcgcgat
      841 gtcaatctct tcccctactt caatgatcca gatgaggatt tcttgaccta tgtgggacaa
      901 ttctatcaag aaaaatctca cctagttccc aatgaggtac tgattccgca ggatattgac
      961 gaagaggctg tcaaggcctt ggtggattcc aagattctta agcctcaacg tggagagaaa
     1021 aagcagctgg tcaatttagc tataaaaaat gcccgtgtta gcctagagca gaagttcaac
     1081 ctgctagaga aatctgtcga gaagacccaa ggagctattg aaaatctagg acgcttgctt
     1141 caaatcccaa ccccagttcg catcgagtcc ttcgataact ccaacatcat gggaactagt
     1201 cctgtttcag ccatggtggt ctttgtcaac ggcaagccta gtaagaagga ttaccgtaag
     1261 tataaaatca agaccgtagt cgggccagac gactatgcca gtatgcgaga ggtcattcgc
     1321 agacgctatg gtcgagtaca gcgtgaggct ttgactcctc cagatttgat tgtgattgat
     1381 ggggggcaag gtcaagtcaa tattgctaag caagtcatcc aagaagaact gggcttggat
     1441 attccaattg caggtctgca aaagaatgat aagcaccaaa cccatgaatt gctttttgga
     1501 gatccgctgg aagtggtgga cttgtctcgc aattctcagg aatttttcct cctccaacgc
     1561 atccaagatg aggtgcaccg ctttgccatc accttccacc gccaactgcg ctccaaaaat
     1621 tctttctcat ctcaattgga tgggattgat ggtctgggac ctaaacgcaa gcaaaatctt
     1681 atgaagcatt tcaagtcttt gaccaaaatc aaggaagcca gtgtggatga gattgtcgaa
     1741 gttggggtac ctagagtcgt tgcagaggct gtgcaaagaa agttgaaccc gcagggagaa
     1801 gccttgcctc aagtagcaga agaaagagta gattaccaaa cggaaggaaa ccacaatgaa
     1861 ccataaaatc gcaattttat cagatgttca tggcaatgcg acggcgctag aagcagtgat
     1921 tgcagatgct aaaaatcaag gggccagtga atattggctt ctgggagata tttttcttcc
     1981 tggtccaggc gcaaatgact tagtcgccct gctaaaggac cttcctatca cagccagtgt
     2041 tcgaggcaat tgggatgatt gtgtccttga ggctttagat gggcaatatg gcttagaaga
     2101 cccacaggaa atccagctca tgcgaatgac tcagtttttg atggagcgaa tggatcctgc
     2161 aacgactgtc tggctacgaa gcttgccttt gctggaaaag aaagaaattg ctggactgcg
     2221 cttttctatc tctcataatt tgccaaataa gaactatggt ggtgacttgc tagttgagaa
     2281 tgatacagag aaatttgacc aactgctaga tgcggaaacg gacgtggcag tttatggtca
     2341 tgttcacaag cagttgcttc gttatggaag tcaagggcaa caaatcatca atccagggtc
     2401 gattggcatg ccctatttta attgggaggc gttaaaaaat caccgtgccc agtatgccgt
     2461 gatagaagtt gaagatgggg aattggtcaa tatccaattt cgtaaagttg cttatgatta
     2521 cgaggctgag ttagaattgg ccaagtccaa ggggcttccc tttatcgaaa tgtatgaaga
     2581 actgcgtcgt gacgataact atcaggggca caatctggaa ttattagcca gcttaataga
     2641 aaagcatggg tatgtagagg atgtgaagaa tttttttgat tttttgtaag agtttcctaa
     2701 aatagccaat gcaaactaaa aaagcgattg gctggtccaa tcgcttttag tatatcttat
     2761 actcaatgaa aatcaaagag caaactagga agctagccgt aggttgctca aagcacagct
     2821 ttgaggttgc agataaagct gacgtggttt gaagagattt tcgaagagtg ttattgtaac
     2881 tgagattgat ctgggaggta agaaccacct agataggtat tgctgagttt ttcaagggtt
     2941 ccgtcttgat agagttcttt gagcgcttta tcaaattgct ctttaaactc tttttggtcg
     3001 cttgagaaaa tgatataatt gctggggcta tctgcagaag gtaaatcaac gactgagagg
     3061 tctaaaccac ggtccttgat aatcttttga acggatacct tgtcaaaaac taggaaatca
     3121 aactctccgt tagcaaggtc taggattcgt ttaccaatat cctcaccaga aaaattaatt
     3181 gtagcgggat tatcagtgtg tttctgattc cagttattga tgaattgagc gttagaagtt
     3241 ccggtatcct cttgtgttgt tttaccagcg atctggtcaa gagaagtcaa aggatttttc
     3301 ttgttgctga caaggacgag gggattgttg gaaattggaa gcgagtaaag gtatttttca
     3361 gcacgctctt ttgtgtaact caagttattg gccgcagcct gatagtgacc agaatcaagt
     3421 cctgggaaga tgctctccca ggcggttctt tggaattgaa tctcgtagtc gctgagtttt
     3481 tcatctactg cctttaaaac ttcgatatcg aagcctgtca gattgccctt gtcttcgtag
     3541 tcaaatggtg gcacgtcgcc agctgtagca aggacgattg tcttttgagc gctagtctct
     3601 ttgggtgtag cttgattccc acaggcaacc aaaaatggta ggatagctag taataggcta
     3661 aattttttca tactgtctcc attcaaatgt aaagtacttg ctagtttatc agaaactttc
     3721 ctgataaacc aatatatatc ttttatgtct gtgatagaaa aacttaatca tgaaaaatcc
     3781 ctgcaagctc tttcaaatta tggtagaatg gaagcagtag aattagaaaa ggaaatcgat
     3841 tatgaaattt cttgaattaa ataaaaaacg tcatgcgact aagcatttta ctgataagcc
     3901 tgttgatccc aaagatgtgc gtacggctat cgaaattgca accttggcgc caagcgccca
     3961 caacagccag ccttggaaat ttgtggtggt acgtgagaaa aatgctgaac tggcaaagtt
     4021 agcttatggt tccaattttg aacaggtatc atcagcgcct gtaaccattg ccttgtttac
     4081 agatacggac ttagccaaac gtgctcgtaa gattgcccgt gttggtggtg ctaataactt
     4141 ttctgaagag caacttcaat attttatgaa aaatctgcca gctgagtttg cccgttacag
     4201 tgagcaacaa gtcagcgact acctagctct caatgcaggt ttggttgcca tgaacttggt
     4261 tcttgcattg acagaccaag gaattggttc taacattatt cttggttttg acaaatcaaa
     4321 agttaatgaa gttttggaaa tcgaagaccg tttccgccca gaactcttga tcacagtggg
     4381 ttatacagac gaaaaattgg aaccaagcta ccgcttgcca gtagatgaaa tcatcgagaa
     4441 aagatagaaa gaagaaaaaa tgacagcaat tgattttaca gcagaagtag aaaaacgcaa
     4501 agaagacctc ttggctgact tgtttagcct tttggaaatc aattcagaac gtgatgacag
     4561 caaggctgat gcccagcatc catttgggcc tggtccagta aaagccttgg agaaattcct
     4621 tgaaatcgca gaccgcgatg gctacccaac taagaatgtt gataactatg caggacattt
     4681 tgagtttggt gatggagaag aagttctcgg aatctttgcc catatggatg tggtgcctgc
     4741 tggtagcggt tgggacacag acccttacac accaactatc aaagatggtc gcctttatgc
     4801 gcgcggggct tcggacgata agggtcctac aacagcttgt tactatggtt tgaaaatcat
     4861 caaagaattg ggtcttccaa cttctaagaa agttcgcttc atcgttggaa cagacgaaga
     4921 atcaggctgg gcagacatgg actactactt tgagcatgta ggacttgcca aaccagattt
     4981 cggtttctca ccagatgctg aatttccaat catcaatggt gaaaaaggaa atatcacgga
     5041 atacctccac tttgcaggag aaaatacagg tgttgcccgt cttcacagct ttacaggtgg
     5101 tttacgtgaa aatatggtac cagaatcagc aacagcagtc gtttcaggtg acttggctga
     5161 cttgcaagct aaactagatg cctttgttgc agaacacaaa cttagaggag aactccaaga
     5221 agaagctggc aaatacaagg tgacgatcat tggtaaatca gcccacggtg ctatgcctgc
     5281 ttcaggtgtc aatggcgcaa cttaccttgc cctcttcctc agccagtttg gctttgctgg
     5341 tccagccaaa gactaccttg acatcgcagg taaaattctc ttgaacgatc atgagggtga
     5401 aaatcttaag attgctcatg tggatgaaaa gatgggtgct ctttctatga atgccggcgt
     5461 cttccgcttc gatgaaacaa gtgctgataa taccattgcc ctcaacatcc gctatccaaa
     5521 aggaacaagt ccagaacaaa tcaagtcaat ccttgaaaac ttgccagttg tttctgttag
     5581 cctgtctgaa cacggtcaca cgcctcacta tgtgccaatg gaagatccac ttgtgcaaac
     5641 cttgttgaat gtctatgaaa aacaaactgg ccttaaaggt catgaacaag tcatcggtgg
     5701 tggaaccttt ggtcgcttgc tagaacgcgg agttgcctac ggtgctatgt tcccagactc
     5761 gattgatacc atgcaccaag ccaatgaatt tatcgccttg gatgatcttt tccgagcagc
     5821 agcaatttat gccgaagcta tttacgaatt gatcaaataa aacgatagaa gtctgagatc
     5881 ttatgcttgg acttcttttt ggagggaaag tagatgtctc aaatcgaaag aatcaaacag
     5941 gctatcatgg cggattcaca gaatgccagc tatacagagc gtggcattga gcctctcttt
     6001 gcagcgccaa aaactgctcg catcaatatc atcggtcagg ctccgggact taaaactcaa
     6061 gaagcaggcc tttactggaa agataaaagt ggtgaccgct tgcgggactg gctaggtgtg
     6121 gatgaagata ccttttacaa ttcaggttat tttgctgttt tgcctatgga tttctacttt
     6181 ccaggacatg gcaagtcggg tgatcttccg cctcgtacag gttttgcaga aaaatggcat
     6241 ccgcagctct tacaggaatt gcctgatatt cagttaaccc tcttgattgg gcaatatgcc
     6301 caagcctact atttacagga gaaaatcagt gggaaggtaa cggagagggt gaaacactat
     6361 aaagactatc tgccagccta ttttccgcta gttcacccat caccacgaaa tcaaatctgg
     6421 atggccaaaa atccttggtt tgaggcagaa gtagtgccag atttgaaaaa aagaattaaa
     6481 accattttat agtcaatgaa aatcaaagag caaactagga agctagtcgt aggctgctca
     6541 aagtacagct ttgaggttgc agataaaact gacgaagtcg gtaacatacg cacggtaagg
     6601 cgacgctgac gtggtttgaa gagattttcg aagagtatta gaagaaaaag aatgaaagaa
     6661 atagcctttg acgcatttta ccagctttac caaaacgacc agctttctct agtggatgtg
     6721 agagaagtgg atgagtttgc agctcttcat ttagaaggtg cccgcaacct accgcttagt
     6781 caattggctg atagttatga ttaattggac aaagatcgct tgcattatat tatttgcaaa
     6841 tctggaatga gatcggcgcg tgcttgccaa ttcctattag aacaaggtta taatgttatc
     6901 aatgtccagg gtggcatgtt agtctttgaa gaactttaaa attttgcatt tctcctactt
     6961 ggtgtggact gggtaggaga gttttatttt tagataattc ttatttttaa gaaaattgaa
     7021 aatatttaat atttgcctcg tgatactttt ttcagactcc taattgtggt atactaggtc
     7081 agtattttat aaatatgaag gagattttta tggctaaaaa aggtacccta acaggtttgc
     7141 tcctgtttgg aatatttttt ggtgcgggga acttgatttt tccgccttct ctaggtgctc
     7201 tatctggaga acattttctt cctgccatcg caggttttgt cttttcaggc gttggtatcg
     7261 ccgtcttgac ccttattatt ggaacgctaa atcctaaagg atatatctac gagatttcaa
     7321 cgaagatagc gccttggttt gcgactcttt acctctcagt tctttacttg tcaatcggtc
     7381 cattctttgc taccccacgt actgctacaa cagcttacga agtagggatt agcccccttt
     7441 tgtcggatgc aaataaagga cttggcttga ttgtatttac ggttctgtat tttgcggcag
     7501 cctatttgat ttcgcttaat ccatcaaaaa tcttagaccg cattggacgt attttaacgc
     7561 cagtctttgc aattttgatt gttatcttgg tcgttctggg agctatcaaa tatggtggaa
     7621 caagtcctca agctgcttca gctgcttatc aagcttctgc ctttggtaca ggtttcctag
     7681 aaggttacaa taccttggac gcccttgcct cagtggcctt tagcgtaatc gcagttcaaa
     7741 ccttgaaaca acttggattt tcaagtaaga aagaatacat ttcaactatt tgggttgttg
     7801 gtatcgttgt tgcccttgcc ttcagcgctc tttacatcgg tttaggtttt cttggaaatc
     7861 atttcccagt accagctgaa gcgatgaagg gtggaacacc aggtgtttac atcttgtcac
     7921 aagccactca agaaatcttt ggctcaacag ctcaactctt ccttgcagct atggttaccg
     7981 taacctgctt cacaacgact gttggtttaa ttgtgtcaac agctgagttc tttaatgagc
     8041 gcttcccaca aatcagctac aaggtttatg cgacagcctt taccttgatt ggatttgcta
     8101 ttgccaattt gggtcttgat gcgattatca agtactcaat tccagtactg gttatcttgt
     8161 acccaatcac gattgctatc gttatgattg tcatggtcaa caaatttgtt gccctttcaa
     8221 aaccaggtat gcagttgaca attgctgtgg ttacagttat tgccattgca agcgtactag
     8281 gaagctcgtt taaggttgag tttcttgcaa atcttgttag cgttcttcct tttgccaagg
     8341 catctctccc atggttggtg ccagccattg ttggaatctt gctctcattg gttctaccaa
     8401 acaagcaaga aagcgatgtt tttgaaatgg aataatcact taaatcactt ttgtagccaa
     8461 gtctacagga gtgattttct ttttttatcc gatgataaat gtgttataat aggtagcgaa
     8521 agaggtgaag aaatgaatca aacagtaaaa tatatcaaag aactgacagc catcgcatcg
     8581 ccaacgggct tcactcgtga aatttcgaat tatttagtca agactctaga aggttttggt
     8641 taccagccgg ttcgcacagc caagggtggt gtcaatgtga ccatcaaagg tcaaaatgat
     8701 gaagagcatc gctatgtgac tgcccatgtg gatacgttag gtgccattgt tcgtgctgtc
     8761 aaaccagatg gccgtctcaa aatggaccgt atcggtggtt ttccttggaa tatgattgaa
     8821 ggtgaaaact gtaccattca tgtggctagc acaggtcaaa aggtatcagg taccatcctc
     8881 atccaccaaa cttcttgcca tgtctacaag gatgcaggaa ctgcagaacg cacgcaggat
     8941 aatatggaag tacgtttgga cgcaaaagta agcaatgaaa aagaaactcg tgccttgggg
     9001 attgaggtcg gtgattttat cagctttgat ccacgaactg tcgtgacaga ggcaggtttt
     9061 atcaagtctc gtcatttgga cgataaggtc agtgcagcaa ttttgcttaa tctgcttctt
     9121 atttataaga aagagaaaat tgaattgcca gtaacaactc attttgcttt ttcagttttt
     9181 gaagaagtag gacatggtgc taattctaac attcctgctc aggtagtcga atatctggct
     9241 gttgatatgg gagctatggg cgatggccag caaacagatg agtacacagt gtctatctgt
     9301 gtcaaggatg cctcaggccc ttatcactat gacttccgtc aacatttggt gaccttggcg
     9361 aaagagcaag atattccttt taagctggac atctatccat tttatggttc ggatgcttca
     9421 gcggccatgt ccgcaggggc agaggtcaaa cacgccctcc ttggcgcggg tatcgagtct
     9481 agtcattctt atgagcgtac tcatattgac tcggtggtcg caacagagcg tatggttgat
     9541 gcttacatta agagcgcgtt ggtagactaa tatgtgtctt atatgccaga gaattgagct
     9601 catcaagaag ggagaaaatc cctattttgt caaagagttg gaaacaggct atcttgtgat
     9661 tggagatcac cagtattttg caggctatag tctctttcta gccaaggaac acgtcacgga
     9721 attgcaccat ttagaaaagg aaacaagact acgttttctc gaagaaatga gtctagtcca
     9781 agaggcagtt gctaaggcct ttactgctga gaaaatgaat atcgaactgc taggaaatgg
     9841 cgatgcccat cttcattggc atctgtttcc tagacgaaca ggtgacatga atggtcacgg
     9901 tctcaatgga cgtggtccag tctggtgggt tccttttgaa gaaatgacag cagaaacctg
     9961 ccaagcaaaa tcggatgaga ttaaacaatt agtcaaacgt ttatcgtcag aactagataa
    10021 actattagaa ataaaggagt agaaatgaaa aaaagatacc ttgtcttgac agccttgcta
    10081 accttgagtc tagcagcttg ttcacaagaa aaagcaaaaa atgaagacgg agaagctaag
    10141 acagaacaga cagccaaaac tgatggaaca gtcggaagta agtctcaagg aactgcccag
    10201 aagaaagcag aagtggttaa caaaggagac tattacagca ttcaagggaa atacgatgaa
    10261 atcatcgtag ccaacaaaca ctatccattg tctaaagact ataatccagg ggaaaatcca
    10321 acagccaagg ctgagttggt taaactcatc aaagcgatgc aagaggcagg tttcccaatc
    10381 agtgaccatt acagtggctt tagaagttat gaaactcaga ccaagctcta ccaagattat
    10441 gtcaatcaag atgggaaaga agctgctgac cgttattctg ctcgacctgg ctatagcgaa
    10501 caccaaacag gcttggcctt tgatgtgatt gggactgatg gtgatttggt gacagaagaa
    10561 aaagcagccc aatggctctt ggaccatgct gctgattatg gctttgttgt ccgttatctc
    10621 aaaggcaagg aaaaggaaac aggctatatg gctgaggaat ggcacttgcg ttatgtcgga
    10681 aaagaagcaa aagaaattgc tgagagtggt ctcagtttgg aagaatacta tggctttgaa
    10741 ggcggagact acgtcgatta atactcttcg aaaatctctt cagaccacgt cagcgtcgcc
    10801 ttacctactg actgcgtcgg ttctattcac aacctcaaaa cagtgttttg agcagcctgc
    10861 ggctagcttc ctagtttgct ctttgatttt cattgagtat aaaaaataaa cttttctctt
    10921 gcaattccag ataaatagtg tataatggat gggtatgtga aaaacatact tgtgggaggt
    10981 aaaaatctta cattaccgcc aaaaccacaa aggaggattt agaaatggct aaaaaagtcg
    11041 aaaaacttgt aaaattgcaa atccctgctg gtaaagctac accagctcca ccggttggac
    11101 ctgctcttgg tcaagctggt atcaacatca tgggattcac aaaagagttc aacgctcgta
    11161 cagctgacca agctggtatg atcattccag ttgttatctc agtttacgaa gataaatcat
    11221 ttactttcgt tacgaaaaca ccaccagctg ctgttctttt gaaaaaagct gcaggtgttg
    11281 aaaaaggatc aggtacacct aataaaacta aagttgctac agttactcgt gcacaagtac
    11341 aagaaattgc agaaactaag atgccagatt tgaacgcagc aaacgtagag tctgcaatgc
    11401 gtatgatcga aggtactgct cgttctatgg gattcactgt tgttgactaa tcaataacac
    11461 agtagaaaat ctcacagcag tctattagtt gcttttcata ctaggcaagt gactgagcct
    11521 tgtacttggg tacagcaagg gagcttaagg ccgtaggaag agaaaaatag tagactgaaa
    11581 acccgcaaga cttcatcatt tcgagaagtg acgtgggaga tgaaaatcga ttgaaccact
    11641 tacaaggaga atagaaaatg gctaaaaaaa gcaaacaact tcgtgctgct cttgagaaaa
    11701 tcgacagcac aaaagcatac agtgtagaag aagctgtagc acttgcaaaa gaaactaact
    11761 ttgcaaaatt tgacgcaact gtagaagttg cttacaactt gaacatcgac gttaaaaaag
    11821 ctgaccaaca aatccgtgga gcaatggtat tgccaaacgg tactggtaaa acttcacgtg
    11881 ttcttgtttt cgcacgtggt gcaaaagctg aagaagcaaa agctgctggt gcagactttg
    11941 ttggtgaaga tgaccttgtt gctaaaatca acgacggttg gttggacttc gacgtagtta
    12001 tcgctacacc tgatatgatg gctcttgttg gacgtcttgg acgtgtcctt ggaccacgta
    12061 acttgatgcc aaaccctaaa actggtactg taacaatgga tgttgctaaa gcagttgaag
    12121 agtctaaagg tggtaaaatc acttaccgtg ctgaccgtgc aggtaacgtt caagcaatca
    12181 tcggtaaagt atcatttgaa gctgaaaaat tggttgaaaa ctttaaagct ttcaacgaaa
    12241 caatccaaaa agcaaaacca gctacagcta aaggaactta cgtaacaaac ttgactatca
    12301 caactactca aggtgttggt atcaaagttg acgtaaactc actttaatca gtagttaaag
    12361 taatgtaaaa aagttgaaga cgctatgtct caactttttt tgatgtacga cgggcatgtt
    12421 gtatagtaga ttgaaactag aatagtacac atctacttct aaaacattgt tagaaattga
    12481 tttgactgtc ctgatcgatt cgtcctattc ttatttcatt ttattatata tttgaggtgt
    12541 aagtcctcgg tgggcacctg ctaccggtga acccaatagc gattcccaag tctgactatc
    12601 gtgaggtagc ggattaaaac ggtctgggga tagaccgttt taagtctgac gctggaaata
    12661 agaatcgtca gaggaaggga tagcgaaatc gtggctctac gaacaggaac gtgataataa
    12721 ggcctatata gcggataagg tatctggctg gggcgaccac tatcaattag tagctcagaa
    12781 gtcggtactt aaacgtgcta tatcaaaacc agtccttgaa aaacgtggac tggtttcgtg
    12841 tttggattat taccttgaat gacatgcgtt aacagttagt tgaaccgccg tatgccgaac
    12901 ggcacgtacg gtggtgtgag aggggctaga gattatcccc tactcgattt cgaaatctag
    12961 tggaatgaat ctggaatagt ccatcgagct ttctaatact cttcgaaaat ctcttcaaac
    13021 cacgtcaacg tcgccttgcc gtgcgtatgg ttactgactt cgtcagttct atccacaacc
    13081 tcaaaacagt gttttgagca acctgaggct agtttcctag tttgctcttt ggttttcatt
    13141 gagtataaca gattgttaga agttggttta aatttcctaa tcagtttgtt cacatttacc
    13201 ttcgatatat tatatcccat agttaaggtt ggtcatacag atgattatag tcatggagcc
    13261 gtaaaactta gtgtttcttt agttgacaaa gatgccatga aaacaatatc tgtaactgta
    13321 ataggatatt ttgaaataaa tatagatgaa aatatcaccg atattctata cgtaaatggt
    13381 actgctattc tttatcatta tttacgttct attgtttcaa tagtttcggc aattgatagc
    13441 agtgaagcaa tgttgctacc taccattaat gttttagagt tactagataa atctcaacct
    13501 tttgaagaag aataatttat tagctcacta aattgagggt aaggaaaagt aaaagcagta
    13561 agaaaaatgt cttgcattat acagcaacct tttgggaatg agtagatgga ttgaataaaa
    13621 ttttattaag agtggatgat ttatctgtag attattattg gacagttagt cttgaagtag
    13681 tctaagaatt aggttataat cagtagaatc cttgctaata atgaggaggt tagtttatgt
    13741 atagtagact gaatctaaaa tagtacgaaa caattgctaa aacatttata gaaattaatt
    13801 ttactttccc aatcgatttg ttctcatctt atttcaatcc gctatatatt atggtatcga
    13861 atcttcatca gaatgataaa attaatcaat tgatatctga ttacaaacag aatatgaaag
    13921 ctttttatat cactattgaa aaatttatac gagatgatga aagccttaag tgttatttta
    13981 taaaggttat ttcaagtcgt tccaaggtaa caagtctaga tcagattgaa gctgataaaa
    14041 cgatacaaag aaaatattca agtgagctaa aaaaatttat tggattttat aatgagatta
    14101 tttgtgagga aaatagtttc ctacatgtac gaaagaggtg gtcgagttgg tttaggtagt
    14161 cgatgcgtga gttgataatt ctcagggtat ggacttcttt ttcatgaatg aggtaaaaga
    14221 gcaggtattg tttagagaca atcattctga gcatattttc tggatagagg gagtatccga
    14281 ttttatgatc aaagttaata ccgccctctg gtgagaagat gagtaggttg gtaatttaaa
    14341 ctattaaaca gaatttttga ttaaaagtat tattttatga gagaaatcct aatttcacaa
    14401 tccataggca atcgcttgca ttctgttttt tattggacta taataggttg gtataaagcc
    14461 ttctgtagta ataaaatgta gaaggtgtag aaagtaagga tttagaatat ttgtagttaa
    14521 aaacacaatg ttgctattcc ttacgatagg gagatagata tggcaatgat agaagtggaa
    14581 catcttcaga aaaattttgt gaagactgtt aaggaaccgg gcttgaaggg ggctttgcgc
    14641 tcctttattc atcctgaaaa gcagaccttt gaagcggtca aggatttgac ctttgaggtt
    14701 ccaaaagggc agattttagg atttatcggg gcaaatggtg ctgggaagtc gacaaccatt
    14761 aaaatgctga caggaatttt gaaaccaaca tctggttttt gtcggattaa cggcaagatt
    14821 ccccagaaca atcggcaaga ttatgtcaaa gatattggcg tagtctttgg acaacgcacc
    14881 cagctatggt gggatttggc tctgcaagag acctacactg tcttaaaaga gatttatgat
    14941 gtgccagact cgctctttca taagcgtatg gactttttga atgaagtctt ggatttgaag
    15001 gactttatca aggatcccgt gcggactctt tcactgggac aacggatgcg ggcggatatt
    15061 gcggcctcct tgctccacaa tcccaaggtt ctttttttag atgagccgac cattggtttg
    15121 gacgtttcgg ttaaggataa tattcgtcgg gcaattactc agatcaatca agaggaagaa
    15181 actaccattc ttttgaccac tcacgatttg agtgatattg agcaactttg tgatcggatt
    15241 ttcatgattg acaaggggca agagattttt gatggaacgg tgagccaact caaggagacc
    15301 tttggtaaga tgaagactct ctcttttgaa ctgctaccag gtcaaagtca tctcgtctct
    15361 cactatgaag gtctgtctga tatgaccatt gatagacaag gaaacagcct caacattgaa
    15421 tttgatagtt ctcgctacca gtcagctgac attatcaagc aaaccctgtc tgattttgaa
    15481 atccgcgatt tgaagatggt ggatacggat attgaggata ttatccgtcg cttctaccga
    15541 aaggagctct aggatgatca aattgtggag acgttataaa ccctttatca atgcaggggt
    15601 tcaggagttg attacttacc gagtcaactt tattctctat cggattggcg atgtcatggg
    15661 ggcttttgtg gccttttatc tctggaaggc tgtctttgat tcttcgcaag agtctttgat
    15721 tcagggcttc agtatggcgg atatcaccct ctacatcatc atgagttttg tgaccaatct
    15781 tctgactaga tccgattcgt cctttatgat tggggaggag gtcaaggatg gctccattat
    15841 catgcgtttg ttgcgaccag tgcattttgc ggcctcctat cttttcaccg agcttggttc
    15901 caagtggttg atttttatca gcgttggcct tccattttta agtgtcattg tcttgatgaa
    15961 aatcatatcg ggtcaaggta ttgtagaggt gctaggatta actgtccttt atctttttag
    16021 cttaacgctc gcctatctga ttaacttttt ctttaatatt tgctttggat tttcagcctt
    16081 tgtgtttaaa aatctttggg gttccaacct acttaagact tccatagtgg cttttatgtc
    16141 ggggagtttg attcccttgg cattctttcc aaaggttgtt tcagatattc tttccttttt
    16201 gcctttttca tccttgattt atactccagt tatgatcatt gttggaaaat acgatgccag
    16261 tcagattctt caggcactcc ttttgcagtt cttctggctc ttagtgatgg tgggattgtc
    16321 tcagttgatt tggaaacggg tccagtcctt tatcaccatt caaggaggtt agtatgaaaa
    16381 aatatcaacg aatgcatctg atttttatca gacaatacat caaacaaatc atggaatata
    16441 aggtggattt tgtggttggt gtcttgggag tctttctggc tcaaggcttg aatctcttgt
    16501 ttctcaatgt catctttcaa catattccat tcctagaagg ctggaccttt caagagatag
    16561 ctttcattta tggattttcc ttgattccca agggaatgga ccatctcttt tttgacaatc
    16621 tctgggcact agggcaacgc ctagtccgaa aaggagagtt tgacaagtat ctgactcgtc
    16681 ccatcaatcc tctctttcac atcctagttg aaacctttca gattgatgcc ttgggtgaac
    16741 tcttagtcgg tggtatttta ttgggaacaa cagtgaccag cattgtttgg actcttccaa
    16801 aattcctgct tttcctagtt tgtattcctt ttgcgacctt gatttatact tctcttaaaa
    16861 tcgcaacagc cagtatcgcc ttttggacta agcagtcagg cgccatgatt tacatcttct
    16921 atatgttcaa tgactttgct aagtatccga tttctattta caattctctt cttcgttggt
    16981 tgattagctt tatcgtgcct ttcgccttta cagcctatta tccagctagc tatttcttac
    17041 aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt gatttctctg gttttctttg
    17101 ttatttccct taaactttgg gataagggct tagattccta cgaaagtgcg ggttcgtaaa
    17161 agctaaagta agactaaaat caagaaagaa acttatgatg tttgtaattg aagaagtcaa
    17221 ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg aaggatttgc cagaatggtt
    17281 tggaatccca gaaagcacac aagcctatat agaaggaacc acgacactgc aagtttggac
    17341 cgcctatcag gagagtgatt tgactggatt tgtaagctta tcctattcga gtgaagattg
    17401 tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag gtagaaaaat tgggagccaa
    17461 ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg gttatctgca ggtcaaaaca
    17521 gtggcagaag gttctaataa agattatgat cgaacaaatg acttttatcg aggtcttggc
    17581 tttaaaaagt tagagatttt tcttcaacta tggaatccgc aaaatccttg tcagattttg
    17641 attaaaaagc ttgaataata ttacttgaca tctattctca gagtgctata ctgtaagtgt
    17701 aatcgccgat ttagcttagt tggtagagca aggcactcgt aaagcctagg ttataggtag
    17761 ataaacgact gaggatttga aaaaatagat aggtagaaga taaccgttaa gccttattct
    17821 tagcggttat ttatattgtt taatagcgct gatatttcat caattatgcc tgttttcgtg
    17881 tttctggtag ttgttcaagt ttattgctac tatttttgat ggtatgaatg tgcttataat
    17941 gtatccctgt taagtacgaa acttttgcat tattttttaa catatattaa aaaataaatt
    18001 aatgtgtatt aatttttctt gaattaattt tttttaaatg atatactgtt tttatggaga
    18061 gataacaatt atatataaat gtactactct atttcctaga taatacttag taaaactttt
    18121 tataacaaag gctagcaaag ttaaagttta ttatctattg gaagttatat aaatatgtaa
    18181 ggaattaaaa tgaaaaaaag tacagtattg tcattaacca cagctgcagt tattttagca
    18241 gcctatgccc ctaatgaggt agtcttagca gacacatcta gctctgaaga tgctttaagc
    18301 atctctgata aagaaaaagt agcagaaaat aaagagaaac atgaagatat ccatagtgct
    18361 atggaaactt cacaggatac tgaagaaaag aaaacaacaa ttattgagga aaaagaagtt
    18421 gttagtaaaa atcctgtgat agacactaaa actagcaatg aagaagcaaa aatcaaagaa
    18481 gaaaattcca ataaatccca aggagatcat acggactcat ttgtgaataa aaacacagaa
    18541 aatcccaaaa aagaagataa agttgtctat attgctgaat ttaaagataa agaatctgga
    18601 gaaaaagcaa tcaaggagct atccagtctt aagaatacaa aagttttata tacttatgat
    18661 agaattttta acggtggtgc tattgaaaca actcaagata atctgaataa aattaaacaa
    18721 atagaaggta ttacatcggt tgaaagggca caaaaagtcc aacccatgat gaatcatgcc
    18781 agaaaggaaa ttggagttga ggaagctatt gattacctaa agtctatcaa tgctccgttt
    18841 gggaaaaatt ttgatggtag aggtatggtc atttcaaata tcgatactgg aacagattat
    18901 aggcataagg ctatgagaat cgatgatgat gccaaagcct caatgagatt taaaaaagaa
    18961 gacttaaaag gaactgataa aaattattgg ttgagtgata aaatccctca tgcgttcaat
    19021 tattataatg gtggcaaaat cactgtagaa aaatatgatg atggaaggga ttattttgac
    19081 ccacatggga tgcatattgc agggattctt gctggaaatg atactgaaca agatatcaaa
    19141 aactttaacg gcatagatgg aattgcgcct aatgcacaaa ttttctctta taaaatgtat
    19201 tctgacgcag gatctgggtt tgcgggtgat gaaacaatgt ttcatgctat tgaagattct
    19261 atcaaacaca acgttgatgt tgtttcggta tcatctggtt ttacaggaac aggtcttgta
    19321 ggtgagaaat attggcaagc tattagggca ttaagaaaag caggcattcc aatggttgtc
    19381 gctacgggta actatgcgac ttctgcttca agttcttcat gggatttagt agcaaataat
    19441 catctgaaaa tgaccgacac tggaaatgta acacgaactg cagcacatga agatgcgata
    19501 gcggtcgctt ctgctaaaaa tcaaacagtt gagtttgata aggttaacat tggaggacaa
    19561 agttttaaat acagaaatat aggggccttt ttcgataaga ataaaatcac aacaaatgaa
    19621 gatggaacaa aagctcctag taaattaaaa tttgtatata taggcaaggg gcaagaccaa
    19681 gatttgatag gtttggatct taggggcaaa attgcagtaa tggatagaat ttatacaaag
    19741 gatttaaaaa atgcttttaa aaaagctatg gataagggtg cacgcgccat tatggttgta
    19801 aatactgtaa attactacaa tagagataat tggacagagc ttccagctat gggatatgaa
    19861 gcggatgaag gtactaaaag tcaagtgttt tcaatttcag gagatgatgg tgtaaagcta
    19921 tggaacatga ttaatcctga taaaaaaact gaagtcaaaa gaaataataa agaagatttt
    19981 aaagataaat tggagcaata ctatccaatt gatatggaaa gttttaattc caacaaaccg
    20041 aatgtaggtg acgaaaaaga gattgacttt aagtttgcac ctgacacaga caaagaactc
    20101 tataaagaag atatcatcgt tccagcagga tccacatctt gggggccaag aatagattta
    20161 cttttaaaac ccgatgtttc agcacctggt aaaaatatta aatccacgct taatgttatt
    20221 aatggcaaat caacttatgg ctatatgtcc ggaactagta tggcgactcc aatcgtagca
    20281 gcttctactg ttttgattcg accaaaattg aaggaaatgc ttgaaaaacc cgtattaaaa
    20341 aatcttaaag gtgatgataa aatagacctt acaagtctta caaaaatagc cctacaaaat
    20401 actgcaagac ctatgatgga tgcaacttct tggaaagaaa aaagtcaata ctttgcatca
    20461 cctagacagc agggggcggg gctaattaat gtggccaacg ctttgagaaa tgaagttgta
    20521 gcgactttca aaaacacgga ttctaaaggt ttggtaaatt catatggttc catttctctt
    20581 aaagaaataa aaggtgataa aaaatacttt acaattaagc ttcacaatac atccaacagg
    20641 cctttaacct ttaaagtttc agcatcagcg gtgactacag attctctaac tgacagacta
    20701 aaactggatg aaacatataa agatgaaaaa tctccagatg gtaagcaaat tgttccagaa
    20761 attcatccag aaaaagtcaa aggggcaaat attacatttg agcatgacac tttcactata
    20821 ggggcaaatt ctagctttga tttaaatgcg gttataaatg ttggggaggc taaaaataaa
    20881 aataaatttg tagaatcatt tattcatttt gagtcagtag aagaaatgga agcattaagc
    20941 tccaatggca agaaaaccga cttccaacca tctttatcaa tgcccctaat gggatttgct
    21001 gggaattgga accacgaacc aatccttgat aaatgggctt gggaagaagg atcaaaatca
    21061 aaaacaatgg aaggttatga tgatgacggt aaaccaaaaa ttccaggaac cttaaataag
    21121 gggattggtg gagaacatgg tatagataaa tttaatccag caggagttat ccaaaataga
    21181 aaagataaaa atagaacatc tctagatcaa gatccagact tatttgcctt taacaaccaa
    21241 ggtgttcatg cagaatccac tagtggttct aagattgcta acatttatcc tttagattca
    21301 aatggaaatc ctcaagatgc tcaactagaa agaggactaa ctccatctcc acttgttcta
    21361 agaagtgcag aagaaggact aatttcaatt gtaaacacca acaaagaagg agaaaaccaa
    21421 aaagacctta aagttgtatc aagagagcac ttcataagag gaattctaaa ttctaaggga
    21481 aatgacgcta agggtatcaa atcatccaaa ctaaaagttt ggggtgactt gaaatgggat
    21541 ggactcatct ataacccaag aggtagagaa gaaaatgccc cagaaagtaa ggataaccaa
    21601 gatccagcta ctaagatacg aggacaattt gaaccgattg cggaaggtca atatttctat
    21661 aaatttaaat atagattaac taaagattac ccatggcagg tttcctatat tcctgtaaaa
    21721 attgataaca cagcccctaa gattgtttcg gttgattttt caaatcctga aaaaattaag
    21781 ctaatcacaa aggatactta tcacaaggta aaagatcaat acaagaatga aactttattt
    21841 gctagagatc aaaaagaaca tcctgaaaaa tttgatgaga ttgcaaatga ggtgtggtat
    21901 gcaggagctg ctcttgttaa tgaagatgga gaggttgaga aaaatcttga agtaacttat
    21961 gcaggtgagg gtcaaggaag aaataggaag cttgataaag atgggaatac tatctatgaa
    22021 attagcggag caggagatct aagaggaaaa atcatcgaag taatcgccct agatggagca
    22081 agcaacttta ccaaaatcca taggattaaa tttgctaatc aagctgatga aaaagggatg
    22141 atttcctatt atctagtaga tcctgatcag gattcatcta aataccaaaa gcttggcgaa
    22201 attcctgaat ctaaatttaa gaatttaaaa aatgttaaag atgatagcct aaacaaagag
    22261 acagctgagg tggaaaataa ccttttagta gataatcagt ctatcgaagg aaaatctctc
    22321 tttaatattc ataaaactat ttcaacaatt agagactttg aaaataaaga cctaaagaaa
    22381 ctcattaaaa agaaatataa gcaagaagac gactttgtaa atggtggaac aagaacagta
    22441 gagcgtgatt ataaatacga tgataaagga aatataatag cctacgatga tgggactgat
    22501 ctagaatatg aaactgagaa acttgacgaa atcaaatcaa aaatttatgg tgttctaagt
    22561 ccgtctaaag atggacactt tgaaattctt ggaaagataa gtaatgtttc taaaaatgcc
    22621 aaggtatatt atgggaataa ctataaatct atagaaatca aagcgaccaa gtatgatttc
    22681 cactcaaaaa cgatgacatt tgatctatac gctaatatta atgatattgt ggatggatta
    22741 gcttttgcag gagatatgag attatttgtt aaagataatg atcagaaaaa agctgaaatt
    22801 aaaattagaa tgcctgaaaa aattaaggaa actaaatcag aatatcccta tgtatcaagt
    22861 tatgggaatg tcatagaatt aggggaagga gatctttcaa aaaacaaacc agacaattta
    22921 actaaaatgg aatctggtaa aatctattct gattcagaaa aacaacaata tctgttaaag
    22981 gataacatca ttctaagaaa aggctatgca ctaaaagtga ctacctataa tcctggaaaa
    23041 acggatatgt tagaaggaaa tggagtctat agcaaggaag atatagcaaa aatacaaaag
    23101 gccaatccta atctaagagt cctttcagaa acaacaattt atgctgatag tagaaatgtt
    23161 gaagatggaa gaagtaccca agctgtatta atgtcggctt tggacggctt taacattata
    23221 aggtatcaag tgtttacatt taaaatgaac gataaagggg aagctatcga taaagacgga
    23281 aatcttgtga cagattcttc taaacttgta ttatttggta aggatgataa agaatacact
    23341 ggagaggata agtccaatgt agaagctata aaagaagatg gttccatgtt atttattgat
    23401 accaaaccag taaacctttc aatggataag aactacttta atccatctaa atctaataaa
    23461 atttatgtac gaaatccaga attttattta agaggtaaga tttctgataa gggtggtttt
    23521 aactgggaat tgagagttaa tgaatcggtt gtagataatt atttaatcta cggagattta
    23581 cacattgata acactagaga ttttaatatt aagctgaatg ttaaagacgg tgacatcatg
    23641 gactggggaa tgaaagacta taaagcaaac ggatttccag ataaggtaac agatatggat
    23701 ggaaatgttt atcttcaaac tggctatagc aatttgaatg ctaaagcagt tggagtccac
    23761 tatcagtttt tatatgataa tgttaaaccc gaagtaaaca ttgatcctaa gggaaatact
    23821 agtatcgaat atgctgatgg aaaatctgta gtctttaaca tcaatgataa aagaaataat
    23881 ggattcgatg gtgagattca agaacaacat atttatataa atggaaaaga atatacatca
    23941 tttgatgata ttaaacaaat aacagacaag acactaaaca ttaagattgt tgtaaaagat
    24001 tttgcaagaa atacaaccgt aaaagaattc attttaaata aagatacggg agaggtaagt
    24061 gaattaaaac ctcatagggt aactgtgacc attcaaaatg gaaaagaaat gagttcaacg
    24121 atagtgtcgg aagaagattt tattttacct gtttataagg gtgaattaga aaaaggatac
    24181 caatttgatg gttgggaaat ttctggtttc gaaggtaaaa aagacgctgg ctatgttatt
    24241 aatctatcaa aagatacctt tataaaacct gtattcaaga aaatagagga gaaaaaggag
    24301 gaagaaaata aacctacttt tgatgtatcg aaaaagaaag ataacccaca agtaaaccat
    24361 agtcaattaa atgaaagtca cagaaaagag gatttacaaa gagaagatca ttcacaaaaa
    24421 tctgattcaa ctaaggatgt tacagctaca gttcttgata aaaacaatat cagtagtaaa
    24481 tcaactacta acaatcctaa taagttgcca aaaactggaa cagcaagcgg agcccagaca
    24541 ctattagctg ccggaataat gtttatagta ggaatttttc ttggattgaa gaaaaaaaat
    24601 caagattaag ataaaagcta tagaaaaaaa tggtttatgt actgagatta gatagtgagg
    24661 tgatgacata gttttgtgaa aacagccatt tataactcaa ttatttagtt tacttcacta
    24721 ttgatactat ttggagttat taatggactt agtttagata actaatgaat tgattgaaag
    24781 ggttagtatt gacaatattg gtcatattga ttagaaaata gagtctatca aaatttaaag
    24841 gctaatagag gtgatgagac aatttcaagg aattaagtag cgtttggttg cttaattcct
    24901 ttttatttgg aaggaagttt ttcgtaaccg cccaataacg aagtctattg gacggttacg
    24961 atatgatcac tgacttcgtc agttctatct acaacctaaa aacagtgttt tgaacaacct
    25021 gcggctagct ttctagtttg ctctttgatt ttcattgaat attagaacag caaaaatgct
    25081 tggagtattt gtttgtgtgt ttgtttttat ataacaaact ataaacaaaa caaaaatata
    25141 aaaaaagaga caaaaaagaa cagaaagtaa ttgacaacgg tttcatatag tgttatactt
    25201 atggcataaa gttaatggaa agaagggaaa accttatggt attagattat ttctttgaca
    25261 aaaaccttgt gttttgctta gaagcggata atcaagaaca actctttgat caggtagcaa
    25321 gcttgttgga agaacgagaa attgtcactc caacttatcg tgaagccttg atcacgcgtg
    25381 aaaagtcatt tccaactggt ttagatatgg aatttctagg aaaggacttg ccaaatgtag
    25441 cgattcctca cacagatatt gttcataatt tggctgaaaa agttgtggtc gttcgattag
    25501 agaaaccggt gactttccat aatatgattg cgccagataa ggaagtagaa gtatccttgc
    25561 tcttctttat catcaataa
//
LOCUS       DAVDHC010000027        25436 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVDHC010000027 DAVDHC010000000
VERSION     DAVDHC010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25436
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.027"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..1157)
                     /locus_tag="VUR43_001593"
     CDS             complement(<1..1157)
                     /locus_tag="VUR43_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET5413256.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTANLKSWKHNVDVFKKAIAYEFDALKEEYISLTFNDKAGIGG
                     SRASGGLSSAADAILGVTESAQEIALDKALQNADLDFDHKAGLLRQEISDG"
     gene            complement(1158..1880)
                     /locus_tag="VUR43_001594"
     CDS             complement(1158..1880)
                     /locus_tag="VUR43_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET5413257.1"
                     /translation="MIKHNELVIDGVRTSSFPFKVIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKSYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVTDLEEVQPGLYMTKATFTCHPTKYFKATDTQRLTRSGTLNVQGSALAFPKITIVG
                     QSAVETSFTIAGQVIRLERLTESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            complement(1877..4636)
                     /locus_tag="VUR43_001595"
     CDS             complement(1877..4636)
                     /locus_tag="VUR43_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HET5413258.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMVKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANKM
                     EAELNQVKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAEALDLTSRATRAAADGAAFYDKSIESVTESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFSSLPAPVKDFVVILGTV
                     VTAVGVIAPIFLSLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILEVINAVVSEISNFIMSIFGTVVAWWTENQELIRASAETVWN
                     AIYTVISTILEILGPLIQAGWDNIQLVITTAWEIIKTVVETAINVVLGIIQAVMQIIT
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNVWNGIKDTV
                     SNVLNAISSTVSSVWEGIKSTISGAINGAKDAVSSAIEAIKRLFNFSISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            complement(4914..5333)
                     /locus_tag="VUR43_001596"
     CDS             complement(4914..5333)
                     /locus_tag="VUR43_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413259.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPQIKPYEQFFMEME
                     IFPIQEVGPVLMEMLNASMTTKKHQMNQNQLAKKSSQ"
     gene            complement(5345..5923)
                     /locus_tag="VUR43_001597"
     CDS             complement(5345..5923)
                     /locus_tag="VUR43_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET5413260.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAMELIL
                     DTKGETTPIKADNKNYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAIMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            complement(5935..6258)
                     /locus_tag="VUR43_001598"
     CDS             complement(5935..6258)
                     /locus_tag="VUR43_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413261.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            complement(6255..6602)
                     /locus_tag="VUR43_001599"
     CDS             complement(6255..6602)
                     /locus_tag="VUR43_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET5413262.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            complement(6599..6898)
                     /locus_tag="VUR43_001600"
     CDS             complement(6599..6898)
                     /locus_tag="VUR43_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HET5413263.1"
                     /translation="MWNHEIKLISKKITGKDKLLQPISEDVEVTLLCRKKNVTRSEFY
                     QANQAGLKPSLVVEIRNFEYENQEFAKFEGKQYRILKTYPIDSEILELTLTEVLK"
     gene            complement(6885..7166)
                     /locus_tag="VUR43_001601"
     CDS             complement(6885..7166)
                     /locus_tag="VUR43_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413264.1"
                     /translation="MDNVQLLELLKLKLGIATKLRDKPLEKIIEAVKTELEDNLGVLL
                     DLDSSEDQMFVVDFAAFRYEGGVDMPRHLQWRLHNLQIASKKKVKNVES"
     gene            complement(7169..7438)
                     /locus_tag="VUR43_001602"
     CDS             complement(7169..7438)
                     /locus_tag="VUR43_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413265.1"
                     /translation="MVYKVIRPFKDLRDPKKHCYKVGDNYPRVKHKLDKEFAETLLNG
                     ANSAGSIFLMNVEDKDMSKDDTLTTEVEKEETKVVDGKPEEGDEE"
     gene            complement(7450..8616)
                     /locus_tag="VUR43_001603"
     CDS             complement(7450..8616)
                     /locus_tag="VUR43_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HET5413266.1"
                     /translation="MNKALIFGARMRAKATKVVELEETIEELNKRSVVELEKLDRAKN
                     DEEVLAVEKTVDGLQREIEEKEAEKVQLENEIDELDKQIKEQNRKAPTPGKMEERGGK
                     TLGQREAFNHYLRTKEARTDGFKSAEGEAIIPVELMTPKEAKQDKTDLTSLVNIVNVK
                     NASGKWSVVKLTDQAMNTVEELEENPELAKPTFTKVNYEIKTRRGHLPVSQEFIDDAD
                     YDVMGLVAKQTKNQERITKNKEIAKVLKTATSKSAAGLDGLKDILNVELKTYYNATIV
                     CTQSMFAALDKIKDKDGRYMLQTDITSPTGYKFAGRVIVVYPDDIIGESKGDLKAFIG
                     DVGEFATLFDRAQTTVKWQDDKIYGQYLATANRFDVVKVDGDAGFYVTYTDAVL"
     gene            complement(8613..9188)
                     /locus_tag="VUR43_001604"
     CDS             complement(8613..9188)
                     /locus_tag="VUR43_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HET5413267.1"
                     /translation="MQKRNSYRATQFQTREEESGDLVLSGYFIKFDEETELWRGYHEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFKL"
     gene            complement(9172..10374)
                     /locus_tag="VUR43_001605"
     CDS             complement(9172..10374)
                     /locus_tag="VUR43_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET5413268.1"
                     /translation="MGIFEKFWKRNKPSKPINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDILYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            complement(10392..10610)
                     /locus_tag="VUR43_001606"
     CDS             complement(10392..10610)
                     /locus_tag="VUR43_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413269.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            complement(10618..12348)
                     /locus_tag="VUR43_001607"
     CDS             complement(10618..12348)
                     /locus_tag="VUR43_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET5413270.1"
                     /translation="MGNLDKAKEYAQHVLTQREEHCEENILAAERFFRDLENPAFEMD
                     VDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            complement(12341..12733)
                     /locus_tag="VUR43_001608"
     CDS             complement(12341..12733)
                     /locus_tag="VUR43_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HET5413271.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            complement(12870..13190)
                     /locus_tag="VUR43_001609"
     CDS             complement(12870..13190)
                     /locus_tag="VUR43_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET5413272.1"
                     /translation="MYNKPVRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            complement(13310..13501)
                     /locus_tag="VUR43_001610"
     CDS             complement(13310..13501)
                     /locus_tag="VUR43_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413273.1"
                     /translation="MIKEYRDDFLGEKAFEKLNKDIDANPGIGFEIVGYTQTAFVNGM
                     HISLTAILVKWGNFFKESE"
     gene            complement(13666..14208)
                     /locus_tag="VUR43_001611"
     CDS             complement(13666..14208)
                     /locus_tag="VUR43_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5413274.1"
                     /translation="MEFVSPIKDSDDIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEDKPFHHFLFKSRQGKNK
                     AITRERAYQIIREAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            complement(14398..14799)
                     /locus_tag="VUR43_001612"
     CDS             complement(14398..14799)
                     /locus_tag="VUR43_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5413275.1"
                     /translation="MKKLSDEELKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     TVGISKPTETIAIRIADDPTLKFLEGFKGIINKLVSNLVEEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAIMKGEL"
     gene            complement(15097..15270)
                     /locus_tag="VUR43_001613"
                     /pseudo
     CDS             complement(15097..15270)
                     /locus_tag="VUR43_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067623.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
     gene            complement(15270..15680)
                     /locus_tag="VUR43_001614"
     CDS             complement(15270..15680)
                     /locus_tag="VUR43_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413276.1"
                     /translation="MIPKFRAYDGGSLSRMYQPDEVMVGNGDIWIIDEDSVAGEWIVN
                     NDLNLMQSTGIRDITNQEIFEGDVVKTTRFVGRADEVGGFYEYDKEFIGIVKQLEGSW
                     VIDTGSDAVCLWTEIEENEIIGNIYENPELLEEK"
     gene            complement(15677..16210)
                     /locus_tag="VUR43_001615"
     CDS             complement(15677..16210)
                     /locus_tag="VUR43_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET5413277.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPQ
                     KVKIPQFVADWIEVCKEHLTTSLYTAMTPNFMKENNQSFDLILWIKKASNQDLFARAW
                     LDGYEVEKEKRYFVKIKGNIKGNMLVYGELLKRYFFTKSFSLDDVIYSHTRKQLEEAG
                     LGWVFDCEGIDIDEVRL"
     gene            complement(16212..16529)
                     /locus_tag="VUR43_001616"
     CDS             complement(16212..16529)
                     /locus_tag="VUR43_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413278.1"
                     /translation="MMEDLKQKVNAVYNWTVEDGKPKPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     GGN"
     gene            complement(16501..16683)
                     /locus_tag="VUR43_001617"
     CDS             complement(16501..16683)
                     /locus_tag="VUR43_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413279.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDDGRFKAKS"
     gene            complement(16810..17037)
                     /locus_tag="VUR43_001618"
     CDS             complement(16810..17037)
                     /locus_tag="VUR43_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413280.1"
                     /translation="MLELYFVYNGHCKFYLGTFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            complement(17037..17231)
                     /locus_tag="VUR43_001619"
     CDS             complement(17037..17231)
                     /locus_tag="VUR43_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413281.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            complement(17246..18016)
                     /locus_tag="VUR43_001620"
     CDS             complement(17246..18016)
                     /locus_tag="VUR43_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5413282.1"
                     /translation="MVDNVFEEIALSYHRSTEQQDEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQVRVNELANAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LAFAKKICREWSEGVRNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLTS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            complement(18010..18168)
                     /locus_tag="VUR43_001621"
     CDS             complement(18010..18168)
                     /locus_tag="VUR43_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413283.1"
                     /translation="MGILELIEQFEDEFYPISDEKKSLLIKQPLSTVTACLSEMASWR
                     ECGGSLSW"
     gene            complement(18156..18989)
                     /locus_tag="VUR43_001622"
     CDS             complement(18156..18989)
                     /locus_tag="VUR43_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HET5413284.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTGNVTVTDGNALDKELDKDKELDKD
                     IEINNNKVMISSSLSENLKNSGIHLTNKSHQQLLEYVGLDGMSFDMLNRAVEKTSGSH
                     KPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKNYNHSRQQNNEISEQEVKDEWG
                     F"
     gene            complement(18982..19278)
                     /locus_tag="VUR43_001623"
     CDS             complement(18982..19278)
                     /locus_tag="VUR43_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413285.1"
                     /translation="MEELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLLVKE
                     YLTDYEKLAKDYRYVTLKNKLLKIEKMELEGRHIYEDMRMKYRANRRKWGARYV"
     gene            complement(19294..19614)
                     /locus_tag="VUR43_001624"
     CDS             complement(19294..19614)
                     /locus_tag="VUR43_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413286.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKKEERREEQEF
                     ASMIIQGYNHAYERGREAERQEIRKNIRRPFKGFTYDNEPPQGLRPEPLALPEPKQSA
                     IRLL"
     gene            complement(19700..19957)
                     /locus_tag="VUR43_001625"
     CDS             complement(19700..19957)
                     /locus_tag="VUR43_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5413287.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            complement(19971..20684)
                     /locus_tag="VUR43_001626"
     CDS             complement(19971..20684)
                     /locus_tag="VUR43_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HET5413288.1"
                     /translation="MNEIFNFHGQEVRTLIIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAQSLLKKRKA
                     RVVACLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNISRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMKLNSFDDV"
     gene            20738..21238
                     /locus_tag="VUR43_001627"
                     /pseudo
     CDS             20738..21238
                     /locus_tag="VUR43_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865135.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(21413..21616)
                     /locus_tag="VUR43_001628"
     CDS             complement(21413..21616)
                     /locus_tag="VUR43_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET5413289.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            21671..22153
                     /locus_tag="VUR43_001629"
     CDS             21671..22153
                     /locus_tag="VUR43_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413290.1"
                     /translation="MKSSFFHYLKEIILYGVLVPILTVIVGFHLFTTFYPISDSLLTD
                     FLKAFTEQRILAIVFVLILCFIFFGSIYYCISCGRNRKLIPDKVYTQITTYISSVGLG
                     TAVIAVATLTLTELQFSILTGWIAFIALLLPLLKFKVQYSTYQSSDNVAQKTTENKAN
                     "
     gene            22459..22824
                     /locus_tag="VUR43_001630"
     CDS             22459..22824
                     /locus_tag="VUR43_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5413291.1"
                     /translation="MFSLFEKIKELCQNRGISINSLEETLGYSRNTIYSMKNKKPNAE
                     RLQEIADYFNVSTDYLLGRTDNPAIAGDSKEYTWQGKTLNVEEMASNVMMFGGRELTD
                     EKKKIIQSIIEGYLKEAGD"
     gene            22837..23220
                     /locus_tag="VUR43_001631"
     CDS             22837..23220
                     /locus_tag="VUR43_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HET5413292.1"
                     /translation="MTEKEIISHFQVRIVDFDGELIPDELGFYEKETNTAFLSNKLSK
                     KERVKVLLHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLK
                     FMSYYNLKTVTNEVMVKEEYLALVN"
     gene            23258..24070
                     /locus_tag="VUR43_001632"
     CDS             23258..24070
                     /locus_tag="VUR43_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET5413293.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYSKYYGD
                     LSAKEIREEVEEYGLKVFKYRDLDIFNIELIPETDNKYDPNAIKVLIFDNHIGYVPAT
                     VSKSIRKYFDDERYHFLIECEIKGGPYKEWDDYEEKVVINNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNIFNKEVTKTESIETKTTEAEHIEQNIVSDSFADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            24244..25392
                     /locus_tag="VUR43_001633"
     CDS             24244..25392
                     /locus_tag="VUR43_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5413294.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGVNTNLTLDQYWDIYSKKRLSTGRWNDTSYYLNDNLYK
                     NHIKTKFGSIQLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
BASE COUNT         7266 a         5692 c         4299 g         8179 t
ORIGIN      
        1 ataccgtcag aaatttcctg tctaagcaat ccagccttat gatcaaagtc taagtcagca
       61 ttttgaagag ccttgtcaag ggcgatttct tgtgcagatt ctgtcactcc aagaattgca
      121 tcggctgcgc tagataggcc accagaagct ctagaaccac caatacctgc cttatcattg
      181 aaagtcagag agatgtattc ttcttttaag gcatcgaact cataagcaat agctttcttg
      241 aatacatcaa cattatgttt ccaactcttg agattggccg tatcacccat gtgaacaact
      301 tgcccatcaa gttcataagc ttcaatcttg atagcatcag agaccttgtc aatgccctca
      361 tttgagaact tagactgtgc ccacttctgc aactcttcaa cggattttgc gttgttgttc
      421 tcatactctt tttcgtttat ataaggataa gaattaataa gaggactatc aacagtcact
      481 ctgatagttg tttccttttc agcaccttca ggcttaaatg tggatcgagc atgaatcctt
      541 gtaacaacat tttgactgtt tttggttcgt tggtagtcct tcagattctt atgtgttgta
      601 ataacaacac cacgattctc accacgactc ttctttacag tcatcgcaaa gttatcacgc
      661 accagctcgc cttcccacgt tccggcgata ctatgcttgc cgtccagcaa tacagagtac
      721 agggtttctg tctcagtcgt gttgaatgtc ctacggtcct ggatatcact gttgaatgag
      781 aagtctccaa gagccgtttt ggtgttttgt accatgcgag aaagagccat gccacaactc
      841 tgactagtca cactcatttg tgtgatagat cgttgcatca catcatctga aatgtgatag
      901 gctgtgattt ccagatggtc attgtgctca acaggtttct tgatacgaaa tagctgcgct
      961 cctaagacag gagtcggagc ctttatcagc atatcttctt ggatgagctg gtaaatacca
     1021 gaatcagaaa taggatattt cacagtcaag gtaaaatcgc cattcatagt ttctttcaca
     1081 atcgccgaag tcgcttcatg aagtggctcc ccgttccatc gaacggttct tacatcttta
     1141 ttaagtagat aaagcaatta tgcccacccc caaaccgttt cgatttcaat cgattgaata
     1201 cctgggccta aaacaacccc aatattctta actttcgctg gatcaactgt gataaaatcc
     1261 cctgaccatt tcactggctt ccctgttgtc gttttaaagc taggattgtc aggattatta
     1321 accatcacaa gcgactcagt gagtcgttca agacggatga cctgaccagc gattgtaaat
     1381 gaagtctcaa cagcgctctg accaacgatt gtgattttag gaaaagcaag agcagaacct
     1441 tgcacattca gagtcccgct tcttgtcaat ctctgagtat cagttgcttt gaagtatttt
     1501 gtaggatggc aagtgaaggt cgctttggtc atgtaaagac caggttgtac ttcttcaagg
     1561 tcagtcacat tgaccttata gcaccagaga cgagttgttt tgactcgctc gctctctaac
     1621 cagaacttct cacggataaa cagactcata aattggttca tctgctcctc agtcggtttg
     1681 actaagtaaa tcgtataaga tttcttgacc agttccctgt gcttgttcgt ctgaacaatt
     1741 gccccactga caccaccatg ctccaagaga gctgtcttgc tctctcctag agcgattgaa
     1801 ggagagtcat ggacaatgac cttaaatgga aaagacgatg tcctcacacc gtcaatcaca
     1861 agctcattat gctttatcat gcaaaccctc ctctcaattg tctcctacgt tgtaattcgt
     1921 cagcaatacg ctgagccacc tcatcagcaa tccgactgat gtcagcttct tctctgacgg
     1981 tgttaccagt aatagtaatg ttgatggttg gtgaagttcc acccatagtt tgagcgatac
     2041 ctcgaccgat ggctccaagc gttttgtcgt taagtggcaa tactgcttca ttcccagctt
     2101 caccaccaac cattatgtta ttaccattca ttccaaagat agttggtttc gtcatgatac
     2161 cgcctttggc ataccattcg attccaatac ttggaacacc ctgactcaac caatctaatg
     2221 gattggctga accacttaca tagaagtgag gtagtgggat atgtggccag ctaatgctga
     2281 agttgaacaa tctcttgata gcttcaatag ctgaagatac agcatctttt gccccattga
     2341 tagcacctga aatggtactc ttgatacctt cccaaacact tgatacagta ctagatatag
     2401 catttaacac atttgataca gtatccttga tgccgttcca gacatttgat acagttcctg
     2461 aaataccgtt gaggatattt gaaatgtaac tctgaatagc tgaaaaaata gtctgaacaa
     2521 tgctttgaat agcttgccat acagtagaga atactccctt gatagtttcc caagcgcctg
     2581 accaatcacc agtaatgatc tgcataactg cttggataat accaaggaca acattgattg
     2641 cagtctcaac aacggtcttg atgatttccc aagctgttgt aatgacaagt tggatattat
     2701 cccaaccagc ttgaatgagt ggacctaaaa tttccagaat tgtgcttata accgtataga
     2761 tagcattcca gacagtctca gcacttgctc gaataagttc ctggttctcc gtccaccaag
     2821 caacaaccgt tccaaagata ctcatgataa aattagaaat ctctgatacg actgcattga
     2881 taacttcaag aatcgcattc caaacggtcg tgaccgcatc tcgaaaacct tcgttagttt
     2941 cccagaggta ttttacaata acaataattg cagcaactgc agcagcaatt gcaatagctg
     3001 ttccaataat tggcaatgcg gcaattatca tttctccaat agatattttt aaaaactcag
     3061 caagggcttg caacgataag aatatggggg ctatgacccc tacagcagtc acaactgttc
     3121 ctaaaataac aacaaaatct tttactggag caggtaagga actgaacagc tcagctacac
     3181 ctttcacaat cgttgccaag gtttggaaaa cagggatcat catttccaga agaggttgac
     3241 caatagcaga taatgcattg gtcccagctt gtttcagatt ccccataacg ttttctaggc
     3301 cgtctgattc tcttgcagcc tgtccaagag ctcctgagag tttatttccg tcttcgacca
     3361 tctgaagcaa tgtcaattgc ttctgcgctt cgctcaagtc cttgaatgac tttccgtaca
     3421 atttatttgc agctgcattc ctagttgtct ctgtcgcaga gattccaaga gcggcatcgt
     3481 tagcaaagtt tcccttcaaa aaagattgta agctctctgt cacgctctca atagatttgt
     3541 catagaaggc tgcaccgtct gctgctgccc tagttgcacg agaagtaaga tccaaagctt
     3601 ctgctgtatc caatcctgaa gttttggcaa atgaagccat ctgagtgaat gatccttgca
     3661 atcgctctgg gacaatatcc atttcctgac caatagcatt caacgcttct cttgcttggg
     3721 tttccatatc tccgaaaacg gtagtaaatt gagcattact agcttgcatt tgagcagctg
     3781 cttctaacgc ttcttttcct acttccacaa gcttttctga aatagcactc aacttctcac
     3841 taaactgttg aagtagttct gctcttaaat ttcttgagat ttcacttaaa ctttcttgag
     3901 tgctatcagc agcagacttt gttcccttca tctcatcatt gagatgatta aaagcagtct
     3961 taacctgatt tagctcagct tccatcttgt tggcttgtgt ggagttctca ccaaattctt
     4021 ttttagtgat ttccaattgc tgttctagat ttgaaatctg tttacttaca atctcagact
     4081 gagcaccaat ctttttctga gcaagagcat ttctctcggc ttcactagca tttgaaccca
     4141 aagcgctttc ttgcagtttg aatgagcttg tcacctttac catctctgaa gcaagttgac
     4201 tctgctcatt ttgcaactct tttaattggt tcttgttgtt ctgagtagca ctcccattct
     4261 cattaagcgc ctgattcaca tttgcaagct taccctcata tccttttagg acgttttgag
     4321 taacttctac ttcacgttgg aaagcacggt actggtcagc accgatatcg ccatttttga
     4381 attgctgttc cacctgagac tgagcttgtc tcaaggtttc tagtttctct ttggtcgtcg
     4441 aaacttgctt ttgcaagacc tcttgcttct gagtcaggag cgttacgttc cctgtatcaa
     4501 acttcaatgc tttgtcaatc tgtctcaact cctgacttgc atcagtagca gccttattga
     4561 catttttcag cgccttctgt aagggttgcg tgtcgccatc gatttcaatt ttgatacctt
     4621 tgatatttcc tgccatattt cctcctttct caaaaaaata gaaaagcgct gagagaactt
     4681 ctaccactga taatgcagcc agaccaagga acttggtctc agaatcgctc tctcagcact
     4741 catttttctt taaaaactgt caaaatcagc ttgcgtggct ttccgttcgc cacccttatc
     4801 ctcgctccgt agattcacat aatccgtctg ataatccaga gccattccga ttgaaatgtg
     4861 ctttagatca tcaatagaaa gaccagtttc tttacagcaa gataagtagg attctactgt
     4921 gaagatttct tcgctagctg attctgattc atctggtgct tttttgtcgt catgctcgca
     4981 tttagcattt ccatcagcac aggtccaact tcctgaatcg ggaagatttc catttccatg
     5041 aagaattgtt cataaggctt gatttgagga tttgcagatt tagcaaaggt ccaaaaaaga
     5101 cggttgaaaa aggtcatgtc aaaatctgac aacatcgaaa tatcaatatt agtcgctgtc
     5161 aattccttgt cggtttccaa cttgttcaat tcattcatga atgattgatt tttcaacatc
     5221 gagaacaaat cttgaaaata atcttttcca aattgttgct tgtaagcaat aggagtatag
     5281 ccgttggtcc ccaactcata ctcctgatca ccaaccaaaa cgattttacg catagatctt
     5341 ctccttaagc tgcaactgca gtaggttcat acactttctt gaaccagttg tcatacgcat
     5401 ccttgtcatc agctgatgtg atagaacgct tgacaactgt atccaatgga cgcgggctag
     5461 ctttgaaact aagttcacgt tcgttggttg atgtcccgtt cttagttttt gagccaagag
     5521 atgggcgact ggcaaaacag tagtacatca catagcgagt cttgtttttg tcgccttcaa
     5581 actggaacat tattgcgaac tctgtcaagc tcgcatctgc tttttcagtc ataacaccag
     5641 tttgagggtc cttgatttca ccaagaattt ttgtcgcaaa ttcatcaatg atgtgtggga
     5701 ttttaagttt accctcatat ccttcgtttg aattcatgaa atggtaattc ttgttgtctg
     5761 ctttgatagg ggttgtttcc cctttagtat caagtatcag ctccattgct ccaggaaaac
     5821 gaaaaacatc gccgtaagtg ataactccat ctgctgcaag tgtcttgata ggtgcgatat
     5881 gtacattttc taggccaaag gttactttat tttcttgagt catgtcattc ctccttagta
     5941 tagatagact gtgtaagact tgacatagag tctttcagtc tcgataaatg tttcttcttg
     6001 aacttcaaaa aagagcttgt ggtttgccca cagctcttcc agacgttctt ccaaatcttc
     6061 atccttactc tcaaaagcca gctcaactgt cacgctctta atctgatgat taaccgtgtt
     6121 gtcagctgaa ttgatgactg gacttgattc ataatagacc aggtaaggta ggtcaggagc
     6181 gtttccaatt ttaaacgctc gataagtgac aggcaagttt gcctgttcta aaatagcagc
     6241 aaagtctgat agcttcattt cccaatctcc ttgattcgct tctcaaagtt ctgaattgct
     6301 ttttcttcag ctggcttgat gtggacgata ccagcgacac gaccaccatt tcttgaaagg
     6361 tgcccgtttt caagtatgtg agtaagactt gcaactgcgt tgaacacaac aaaagagcca
     6421 ttggccaact tcttcttttt ccaacttcta cgatactttc cgtaccgttt cggacttgtc
     6481 tctttcaact catccacagt ctcatcagtc acttgctctg caatcttatc cacttcttca
     6541 gtaacctcat cagagtaagc tgcaagctct ttcgctatca aatcagcaag gtcattactc
     6601 atttcaagac ctctgtcaaa gtcaactcta aaatttcaga atcgatagga taggttttca
     6661 agatacgata ttgcttgcct tcaaatttcg caaactcctg attctcatac tcaaaatttc
     6721 gaatctcaac gaccaagctc ggttttagac ctgcctggtt tgcttgataa aattcagagc
     6781 gagtaacatt ctttttacga cacaacagag taacttcaac atcttcagag attggttgta
     6841 gtaacttgtc cttacctgtg atttttttag agatcaattt tatttcatga ttccacattc
     6901 ttgacctttt tctttgatgc tatctgtaaa ttatgcagtc gccactgaag gtgacgtggc
     6961 atatccaccc caccctcata gcgaaaggct gcaaaatcaa ctacaaacat ttggtcttct
     7021 gagctgtcta agtcaagtag aactcctaag ttatcttcta gttctgtttt gacagcttcg
     7081 atgattttct ccaagggctt atcgcgtagt tttgttgcta tacccaattt tagcttaagc
     7141 aattctaata attgaacatt gtccataact actcctcgtc tccctcttca ggtttcccat
     7201 ctactacctt tgtttcttcc ttttctactt ctgtagttaa tgtgtcatct ttcgacatat
     7261 ccttatcttc tacattcatc aaaaagatag atcctgcact atttgcccca tttagcagag
     7321 tctccgcaaa ctctttatca agtttgtgct taactctagg gtaattatcc ccaaccttat
     7381 agcaatgttt ctttgggtct cgtaagtcct taaaaggacg gattacctta tataccattt
     7441 actacctcct tacaaaacag catctgtata ggtcacataa aatcctgcat ctccgtctac
     7501 ttttactaca tcaaaacgat tagcggttgc caaatactga ccgtagattt tgtcatcttg
     7561 ccatttgaca gtagtctgcg cacggtcaaa caatgtcgca aattctccaa cgtcaccgat
     7621 gaaggctttc aaatctccct tgctttctcc aatgatatca tctggataaa caacaataac
     7681 acgaccagca aacttgtagc cagttggaga tgtgatatct gtttggagca tgtagcgacc
     7741 gtccttgtcc ttgattttat caagagcagc gaacatagat tgagtacata cgatagttgc
     7801 attgtagtat gttttcaatt ccacgttgag aatatctttc aagccgtcca aaccagctgc
     7861 gcttttagat gtagctgtct tgagaacttt agcgatctct ttattcttag tgatacgttc
     7921 ttggttctta gtttgtttag caaccaatcc catgacatcg tagtcagcgt catcaataaa
     7981 ttcttgagat actggcaaat gaccacgacg tgttttgatt tcatagttca cctttgtaaa
     8041 ggttggttta gccaattcag ggttttcttc caactcttca acagtgttca ttgcttgatc
     8101 agtcaatttt acaactgacc atttaccgct tgcgttcttg acattaacga tgttgaccaa
     8161 tgaagtcaga tctgtcttgt cttgtttcgc ttctttaggc gtcatcaatt caacaggaat
     8221 gattgcttcc ccttcggcag atttgaaacc atcagtacgc gcttcttttg ttcgtaagta
     8281 atgattaaat gcttcacgtt gtcccaatgt ctttcctcct cgttcttcca ttttccccgg
     8341 agttggtgct ttacgatttt gctctttgat ttgtttatct aactcatcga tctcgttttc
     8401 aagctgtact ttttcagctt ctttttcttc aatttccctt tgaagaccgt ctacagtctt
     8461 ttcaactgct aaaacttctt catcattttt agcacgatcc aacttttcta actcaacaac
     8521 cgaacgtttg ttcaattctt cgatagtttc ttccaactca actaccttag ttgcttttgc
     8581 tcgcatacga gcaccaaaga ttaatgcctt attcatagct taaatttctc cttaatttct
     8641 ttcttgcgct tgtctagcgc ttcacgatta gcacgcttct gactttcgaa gtctttttgt
     8701 cgtgcagcaa tttccgtttg tggataggct gggaaagtac atggactcac ttcaaagatt
     8761 tctagctcta agacagtgtc caaatacgaa ccatcttcac gttcttccgt ttcgattttt
     8821 accgggataa agccaaagct acaccctata acatctccac gcttgacacg ggcataggcc
     8881 ccaacagctt gaggatcatc cttgttaatg atgatatctc caaaaagacc aacatcatca
     8941 acacccagtg tcagagttcc gttacctgtt cgaccgagaa caaggctatc atcatggtta
     9001 aataaagctc tgatatcagc gtctgtgaca gctttctcaa caccagcacg cttgattact
     9061 tcatgataac cacgccacaa ctccgtctct tcatcaaatt ttataaaata gccactcaac
     9121 accaagtctc cagattcttc ttctctcgtt tgaaattgag tggcacgata gctatttcgc
     9181 ttttgcattc tcttcctcac ctcccttcag tttattttga tctcctagtt tctcctgagg
     9241 gagaaagttt tcaagaacaa tcaactcttc catctcagga tcaggagcca tccctagcca
     9301 atccctccac tcattacgac gcattgcagc actgtttgcc atttgttgag caacagcaga
     9361 caactccgta atgttgtaag agaagagtga acgaggattt agcttgaagt aacgattgct
     9421 agacaaaagt aagtccctgg ttagtgtttg agtaatagtg gtagcaatac tcatgacagt
     9481 cgtatttaca aagttgttat actctgtctt gttgaactct cctacaccca aaataaaagc
     9541 aggtactcct aatagacctg caactgttct tttatccaat tccacagact cgtttaaagc
     9601 gatgtccgtt agactaagcg gttttacctg ctgaatgtcc agcaatgcct ctggaacaat
     9661 ccatggagcg ccaaccctgc tagtactcaa atacttctca gcgatacgct cacgcccttg
     9721 ctccgaatct agttcagcac tagacgagtc tactttaacg ataagactag gaatattctt
     9781 cccgttcata aagctttttt tagtcttggt agccatgttc aaactttgaa ccacatctgt
     9841 caacgtcacc ctaaaaccag taccaatgta tagaatatct ggatctggat tgatgacgaa
     9901 gtggactact tcatcagggg aatattcttc acccctaaat gagattacat aggaatcctt
     9961 atctgtttgg aatgaaacct ctctcatcgg aaatggtctt agattagaaa tataatccgt
    10021 aacaggttca tattccacat gtaggacaga gttcccatcg ccatataaaa gcaaatcgcg
    10081 cacaatcttg aaaatccatg acttccttgt catgtgttta cacggattga tgtcaatctt
    10141 tctagcaagc ccatcacgga ttctgatatc acctttatct gtattctcca tcaagtggat
    10201 ggtcatatta gagaccaaat cagcaatctt attaaccgct gtcaccacat ctggatttct
    10261 ggccaaaggt acatacgagt ccatcaggtt tgacaaccct aaatctgaat gactcagcat
    10321 gttgattggc ttacttggct tgtttcgttt ccaaaacttt tcaaaaatac ccatgtttcc
    10381 tcacctcctt tctaacgaaa agtattttga aaaagtgaat caaagtgttt atttcttacg
    10441 atattctgac tgacatcaat tacctgtttt tcccatttta ctgtttcagc catcaaattt
    10501 ttcatatgtc tttgacgaat agttactact tccccgttta aaattacttt aactcgccct
    10561 ttgttgatca gcaagttaat ttcatgttct gataatacta tttcattcat aattcaccta
    10621 atcaaagaat ctcatcacat caccaccctt gccaagatta gcaagagcct gtatacaagc
    10681 aaagacgctg gcatcaaaca agtcaatcct tgcagtccca ccgtctccat ctaatttctc
    10741 atattgcaca gcatcgtcca ccttttcaat tgctctaaca ttgctcacac agtattcgta
    10801 agcatcagaa tgaagatagt aaaattcttt attcttaact ttaaactcaa tccgtctgaa
    10861 tccctctgat ttcagataaa aaagctgagg ttggtcaatc atcttgaacc gagcttgttt
    10921 catcttcgtc aagaactcac ggccaaactt cctatccatt ccgacagcag caatcttgaa
    10981 ccctttctcc ctcatcttga tgaaccattt gacgatatca tcatagagga cggtcggagt
    11041 gttgctcatc gtcaaccaac cgtcagactg ccacccaaag agtggaatcc cgtcatcatt
    11101 agcttttttc tgagcattaa tccgagggaa gaaagcatgt gtgatacaga tatcaacgtc
    11161 tttctcaccg tcatgataga caccatagag agcagcagct gttaagtcgt gcaatcttga
    11221 caagtccgcg ccaccatacc aacgaatagg caaacgtgcc agctcttcta aactccaatc
    11281 gtagcaacta tccgacgcaa taaactcatc aggattaaaa taagcgttca tagagttagt
    11341 gaagatattc aaggtcttat tgaaaaactc atttcttgtc tgaggatcat tcatagcctg
    11401 ctctgcttct tccttgagag ccttgagcga aaccgtgaca ccccatgacg gattagccat
    11461 cttgaggata ttctcgtcca gatagttcac cacgtcccca tcagcagatt gattagcttt
    11521 gcagatgaag atgaaaaatg aatcatcagt gactaattgc ttgagcacct tttgacagta
    11581 tttcagacgg ttagcaagga acccggtagg aatatcccca gccgttgaga taacaaaaag
    11641 catactgttt ctgtatgctg acattgtttt tttcataaga ccatgtttct tactgttcct
    11701 cattgtgtga gcttcgtcca agatgataac atttccgttc aaagagtcca gacggctctc
    11761 atcattcgct aaagcctgga taaagaaaga accttcatca ccaaaattgg cagtgataga
    11821 atgttcttgg ttattatcct tgatacgaat gttcttatcg ttccagcgtt caacgttgaa
    11881 tcttaaaaaa ccaaaagctt ccatcgcttg cttgactgag ttagcaacga tatagcattt
    11941 ggaaccgcta tctgtatcta atatctgata agcaagtgcg attgcagcag taaacgaggt
    12001 ctttccattc ttccgagcaa gcatgataag cgcttctttg aacctgcgct cattcgtacc
    12061 cttgtagtaa aaaccaaaca gattaactac aacgaaatgt tgccacggtt gcaaaagcaa
    12121 tggcttgtta cggatagata ccgcaaacat atcatcgccc tgctgatgaa ctatcacgtt
    12181 ctcgataaag tgaataacaa aatccaccat atccacatcc atctcaaacg ctggattttc
    12241 taaatcacgg aaaaaacgtt cagcagcaag aatgttctct tcgcaatgtt cttctcgttg
    12301 agttaagacg tgttgagcgt attcttttgc tttatcaaga ttacccattg ccagtcactc
    12361 gcttcttctt gatttcgttc ttgaacttca ggacctcagt aagaactgac tcaccctctt
    12421 gttctactac ctcaccgagc gacttaggat tcatcatcaa ctgattagag tagctgagga
    12481 tatctttcct caaaatttcc attgctgtca agattggaac tttgcgctca ttctcggcac
    12541 cagccttatt gacgtaggtg tctgttactg gataacccat gtcagcataa tcttgagcaa
    12601 gtttctgata ctggtataac atacctgcaa aaatgtcaat gatcatttcg aactctttac
    12661 gataagttcc caagtctttc atctgcttga ccacttttga cttaatcgac tttgctgtaa
    12721 ttggtttagc caaaaactac ctcctttcgt caaaatcgct tagtttttac cccctttttg
    12781 tttgaaggcc cccgacttgg aaaaagttcc cttcaccggt accctactgg ccgaaatgat
    12841 ttttcaaaaa gaggggggac taaaaatttt catttttcat ttttgaaaaa atttaaaaat
    12901 tctttttttc tttttttctg ccaatacaat ccttgattga ttactctatc gttcactcta
    12961 tcgtgaaacg tattgtgttt tttattcgtc aacggcaaac aattccattc aacgaattca
    13021 agttcaggat attcagatac aggaaagata tggtgaacca tttctgcttg aacagaaatt
    13081 ccgtaacgca aactttcttg gcaaagataa tcatgcttac gcattatcct atcacggaac
    13141 ttctcccact tcttagattt caaggatggt ctgacaggtt tgttatacat ctcaaacctc
    13201 ctttctcaac gctaaaaggg acaggccttt gacctatccc ctcctcatac aagaaatcta
    13261 tgctaccata ataaaccttt ttttgtgaga cttcaagacg tcttttgtct cattctgatt
    13321 ctttaaaaaa attaccccat tttactagta tggctgttag cgatatgtgc attccattta
    13381 caaatgctgt ttgagtatat ccaacaattt caaagccaat gccaggattc gcatcaatat
    13441 ctttatttaa tttctcgaat gccttttctc caagaaaatc atcacggtat tcttttatca
    13501 ttttctacct cctgtaacta taccaatttt acccatcact ttcacatatc ttatattttg
    13561 ttaaactcac tctaaatctc aaacccttac taagcatggg ttttgaagag tttcattttt
    13621 ttagtttatg cttaactcat tatgtgaaag taatatctaa aaaaattaaa tgacaaagtt
    13681 ccgtaaagca tcatcaagct ctgcttgctc tatccctatg tatctcaagg ttattgcagg
    13741 tgatgagtga ttgaacattt tctgtaatgt ccctacgtcc tttgtcttgt tgtaatattt
    13801 atagccgaat gtcttgcgca ttgtatgtgt gccgacatta tcaataccaa gctcttcagc
    13861 agcctcgcga ataatttgat aggctctctc acgagtgatt gctttatttt tcccttgcct
    13921 actcttgaat agaaaatgat gaaatggttt gtcctcgaca tatctcctca tttctttctt
    13981 gagctctttt gtcatccgtc ttgttatctg cttgccagtc ttccgttctc tcagtttgat
    14041 gtgccaacct tgaacatctt taactttcaa ggtaagtata tctccgactc gcaagccagt
    14101 attcaggcct gtaatgaata gcatataata catctcattc cactctctga gataatcttt
    14161 cattgcctga atgtcgtcac tatcttttat cggtgataca aattccataa ctgcctcctt
    14221 tctacaaaac aaaaagccag ctggttgctg actcatgatg ttcctctgtt aaacaacttt
    14281 tctggaaaaa ataggatgac tccaacatgt gatttgtgtt tttgttttca gaagttcatg
    14341 ctatcataat agcccttttt ttgtgagact tcaagatgtc ttttgtatca atcttattta
    14401 caactcacct ttcattatag cgtactgttc taagataatc cttctacgtc gatagattgt
    14461 agctttgctc atgaatttct gttctgctat ttcttcccat ctcagttgag gatatctcca
    14521 gcgcagattg aaaatttctt tgtcctcctc gactagattg cttacgagtt tgttaataat
    14581 ccctttaaat ccttcaagaa attttaaagt cggatcatcc gcgattctga ttgcgatagt
    14641 ttcggtaggt ttgcttattc ctacagtagg cccactttga gcatctggat ttctagtttc
    14701 taattctagc cttcttaagt ctattgtgcg ttgaatattt tgaaatttga aaagttctct
    14761 gtctaacgtt ttgagttctt cgtcgctcaa ttttttcaat ttccacctcc aagtttttaa
    14821 aaaatgtaaa caagttatca aatatttgag ataaagcctt gcgaatatta gaaactgact
    14881 ggttaatcat tttagttata gcttcaattt cttccggact taatttctgt agttgtttgt
    14941 ataattcttc ttgcttttct tgtatctgcc gtttagctat cttcttctta attcttttgt
    15001 tcattgactt ttatttcctt tcttggatct caatcccaaa atcggatatc tattcctact
    15061 tgtcttcgtt ccataaaatc taactgtttg ttcagtaata ccaagttctt tactaaaccg
    15121 taacatatac ttgattgcgt tgccccaaaa gaaagcagac gctccgaaaa gattcccaac
    15181 gaagttatgc acaacatcga tagcctcaag accgtttgca ccttggtagt ggcttggttt
    15241 gtttatattg tcaattattt ctgggttcat tatttctcct ccaaaagctc tggattttcg
    15301 tagatattgc cgatgatttc attttcttca atttcagtcc ataaacatac tgcgtcactg
    15361 cccgtatcaa ttacccaaga accctcaagc tgcttaacaa tccctataaa ttccttgtca
    15421 tactcataaa aaccgcccac ttcgtcagct cttccaacaa atctagtggt tttaacaacg
    15481 tcaccttcaa agatttcttg attagttata tctctgatgc cagttgattg catgaggtta
    15541 aggtcattgt tcacaatcca ttcaccagca acagagtcct catcaataat ccagatatcg
    15601 ccatttccaa ccatcacttc gtccggttga tacatacgac ttaacgagcc accatcatat
    15661 gctctaaatt ttggtatcat aacctcacct cgtctatatc aattccttca caatcaaaca
    15721 cccatccgag gccagcttct tctagttgtt tacgggtgtg ggaatatata acatcgtcta
    15781 aactaaagct ttttgtaaag aaataccttt tcaaaagttc tccataaacc aacatatttc
    15841 ctttaatatt ccctttaatc ttaacaaaat accgcttctc tttctcgacc tcgtagccgt
    15901 caagccatgc gcgagcgaag aggtcttggt tgctcgcctt tttaatccat aatataagat
    15961 cgaaactttg gttgttttct ttcataaagt ttggagtcat agcagtatat agactagttg
    16021 ttaaatgttc tttacaaacc tcaatccaat ccgccacaaa ctgcggaatt ttgacttttt
    16081 ggggttcgtc tagttgtttc aactctttca aaaaaagttc aaccattgaa gtataaggta
    16141 caggttcata aaaagggctg tgttcattcc acaattcttc atacttctta atcaatgcct
    16201 taatattcat cttagtttcc tccataaatc aaataaactg caataactac ctgagccatg
    16261 cttggcgaat agccaaccca atcatcaaac tccttagatt ttggcaacca acccttagta
    16321 gctcccaaat catagtctgt aggcttttca tcagcgaaga tacattccat cgctcccata
    16381 aacgtcatac catcttctgc catttcccaa aaatagtccg cccggtcttt cactgcttgt
    16441 ggtaaatctt gcttgggagg tttgggtttc ccgtcttcta ccgtccagtt gtatactgca
    16501 ttaacttttt gctttaaatc ttccatcatc ttctaaaaat ctttcaatag cttctctgta
    16561 ggagacttcc accagaccgt ctaagtcgtt cagggcttca atatagtctg gacgaccttg
    16621 cccgtactgc tctttcaaaa attcaacaaa gagatgaatt tcctgatagg ttactccaac
    16681 catgtttctt acctcccact aaaaatgtaa cgttattgat catctttctt ttcctttctt
    16741 gctgcacgtt ccccgactaa atagccgaga aataaccaca gaatagccat tccaaattct
    16801 ttaataagtt caatcatttt tttctcctcc tgaaaaagtc gctaaatagt aacaatcctt
    16861 agaaccgtag tcaaatcgtg tcgtccgctg accaatgtgc ttctgaaatc ttggatgagt
    16921 gatagccgag aaagcccact gatgatcttc catctgttca atgagatcat cgacattgtc
    16981 aaacgttcca aggtaaaact tgcagtgccc gttgtagacg aaataaagct ctaacatcac
    17041 tccacctcga cagggtagaa gttcccaaag gaacctctca atgccttgct aacctgtaag
    17101 gctgccgccc gagaaataaa ccgcatggct ttcttctcct cggaacacga aatatccaag
    17161 ccagtcacac tgataattgc agaccttaga aacggcttat cctctcttgt cccatgcttt
    17221 aaaataaaca tcagccaccc ctattctaaa aatattgctt tcgcttgttt gtcaaatcat
    17281 tgaaaaccat caaatggtct ttatctacac ccttcattag tctggacatg aaaggtctgc
    17341 catatctttt ttgaatatcg gcagaagtca aatttgtggt aatgattgta tttgaacgct
    17401 tattcaggat attgtagaga atagtaaacg accattcgct atccttctcc atgcccaaat
    17461 catccaaaac caaaaacttg gcactcgcaa ttttattgac cagaaactct tcctgactaa
    17521 aatcagcttt aatcttcatc aacaagtcag tcacattgat aaatatagca atctctttcg
    17581 tgtactcaga tagagcctta accatagcaa aagccaaatg gctcttaccc gttccagctt
    17641 ctccttgtaa cacgatgttg ttcctaaccc cctcagacca ctcacgacaa atcttctttg
    17701 caaaagctag cttttccgct tctttttcgg ttggcgtctc aaaattgtcc aaagtcgcat
    17761 ttttcaaaac ctcatcataa agagagaact tttcaagata gtatttcctc tctcgctcat
    17821 tctcagcgtt ggccagttca ttcactctta cttgattctc ctcatggatc cgctcagatt
    17881 cacacatgcg acatacaaca ctctcagtcc gcaatatctt tatcaaagga atgttatgct
    17941 tttcgcaaaa ctcatcttgt tgttctgtac tcctgtgata agataaggca atttcctcaa
    18001 acacattgtc taccatgaca gactacctcc gcattcacgc cagctagcca tttcagacaa
    18061 gcaggcagtg acagtagaaa gaggttgttt tataagcaaa gatttctttt cgtcgcttat
    18121 cggataaaat tcatcttcaa attgctcgat aagttctaaa atccccattc gtccttgacc
    18181 tcctgttctg atatttcatt attttgttgt cttgaatgat tgtagttttt accctcttta
    18241 tatttacggt cgtcctcatc cacttgttca atcgatgtga agcctttctt tttccaactt
    18301 tcaagaatag ctattagata attgaaacta ggtttgtgtg accctgaagt tttctcgact
    18361 gcacggttca acatatcaaa actcattcca tcaagtccta catattcaag caactgttga
    18421 tgtgacttat tagttagatg gattccgcta tttttcaaat tttcagagag gctggaacta
    18481 atcatcacct tattattatt tatctctata tctttatcta attctttatc tttatctaat
    18541 tctttatcta gtgcgttacc gtccgttact gtaacgttac ctgtaacgtt accaagagca
    18601 agatttttct gttttttacg gtattttgct acacggttgc gtgtctgttc cttgattttc
    18661 tccattccgt caacgttttg atgtttttcc caatttggca agctaatgat tccatcaata
    18721 atctcaatca tcccgaactg ttcaaagact ccaatagcca ttcttactgt attcaatggt
    18781 ctacgaaaaa tagtagctaa catttcatct gtatagtgaa ccttatcagt catcatcaac
    18841 aaaccattac tgttatgttt tccagcaagt gtcaaaatct taaaccatat cactaagatg
    18901 gcatcgggat caggcaaggc gtcaatcaga caaatctttt catcgtcaaa aatatccgtt
    18961 gtgattttta tccacttaat ttcagacata ccgagccccc cacttcctgc gattggcacg
    19021 atacttcatc cgcatatcct catagatgtg cctgccttcc agctccattt tttcaatctt
    19081 tagcagctta tttttaaggg tcacataacg atagtccttt gctagttttt catagtcggt
    19141 taggtattct ttgactagta atagattttt ataatcgttt tcccatatcg taataaaatg
    19201 tcttgaagtt gattcccttc cttccagttc tttaacaatc ataatcaggt tatccagcga
    19261 ttcaatcaat tcttccattt cctgccctcc tcattacaga agtctgattg cagactgttt
    19321 aggttctggc aaagctaatg gctcaggacg caatccttga ggcggttcgt tgtcgtaggt
    19381 aaagcccttg aacggacgac gaatattctt gcggatttct tgacgttcag cttctctacc
    19441 acgttcgtaa gcatggttat agccttgaat aatcatagac gcaaattctt gctcttctcg
    19501 tctttcttct ttcttgcgtt gttcctgcaa tttgatatga cggcaagccc ctgcaaatcc
    19561 aagcagtaag gctccaaccc ccatcaactg gtctaaaatc ggtggttcaa acatttttat
    19621 ctccttatcc tctttttgtg ctataatata gtcaaataat tttgctaaga ccttgtccag
    19681 aagcctttta gtaaagttat tatatttgat tagagagcca ttctttgatg gctctttttg
    19741 accatttctt accaggtaat tcctttggaa atccctttaa gtaacgataa ttatctgaaa
    19801 atgtggcata cttaattcct agaaaatcac aggtagtgtt cacatccatc aactctggat
    19861 agtgatcact atctttctct atttcgacta gccttgtaat tgtgtccttg ataatagatt
    19921 taatccattc agacagtgaa agtagaacat tgtccatctt cttccccttt ctagacgtca
    19981 tcaaatgagt ttaatttcat gattttcatc ttagtgtttg tgcttggctc ccacgtcatc
    20041 cagtaggcca aggctgcatc tgcaaacttt ttcggtagca aatcatagcg actaatgttg
    20101 aagtggtctt tgaaatcaat ctcagcttgt ctaaagactg actgagcgaa agtcttatcc
    20161 gcataagctg gactatcaat accacctaag caagccacga cacgagcttt gcgcttcttc
    20221 agtaatgatt gagcatagct aggatgaatc ggttgctcac tcttgaggta gtcaatatct
    20281 tccagcatag tcgcttgttg ctcacgcaac ttcttctgtc cagtaaacag agcgatgaaa
    20341 gcatcttcat ccaagtcctc tcggataaat ccgccctgct tgcgaatagc tggcaagacc
    20401 tctgaagtca cccagcgctt gaattcctta gcttgaggca acttgctgga taagatgaga
    20461 gagtagaggc cagattcgtt gatgatgata gtttcttgaa cccttcctaa attatctgtg
    20521 aggccctgtt ttagggcgtc atcttcatca acatgaagag caatcgcatt tctagccttg
    20581 ctatatccta agatgtctgc aacatctttc ccaacgaacc aaggttcgtc atcaataatc
    20641 aaagtacgga cttcctgccc gtgaaaatta aaaatttcgt tcataaagtt cctttctaaa
    20701 tttggtataa tgaaataaaa acgattggag aaaaaatatg actgaaagaa tttgttttat
    20761 tgtaactgct atcggtgaat ctggaacaga aactagagat agagcagatg aggttttttc
    20821 ttacctgata gccccagtct gtgaggaatt aggatataag ccagtacgag ttgaccaagt
    20881 agatgcagtt gataatatca atgaaactat tatcaactac cttaagactg cccctatggt
    20941 tgtagcagat atgacaggac acaatccgaa tgcattttat gaattaggat ttcgacaagc
    21001 aaaagaactc cccttagttc ctatcataca agcaggtaat ggacttcctt ttgatgttat
    21061 atcccaaaga actgttttct ataacctttc tgttggaaaa atcgagcaat ccaaaagaga
    21121 attgaaagct aaaatgaaaa gctttgaaaa ctttgaaatg cctgaaagtc gcattgataa
    21181 aagcgttaca ttagaagagc ttgatgacaa gctaactaaa aaactaaaca agatactaaa
    21241 aacgtccatc tccttaaatt cggcattctc tgcacagtag cggacgctct cgctgatgat
    21301 gtgacaaata gatacgccgt actcgttcgc cagctccgta gcaatctccc aggcatcttt
    21361 gtcaatccgt gttacttttt gcgctgcgtt gttcatacta tttcctcatg ctctaactat
    21421 tttcccaagg gttttcaata cccaaaatat ctacgacttt ttctttcaca taatcacttc
    21481 cttttccata cttcagcagt tctgaaataa ctgatgatgc tacagatact tgttttgcca
    21541 attcggcttg agtcatatcc agctcaatca aacgagtttt gattttagcc ttgattatct
    21601 ttagttcttt actcatattt ttcctttcta aatttgatat aattaaaata aaaacgattg
    21661 gaggagaata atgaaatctt cattttttca ctatctaaag gaaatcatct tatatggtgt
    21721 cctagttccg attttgacag ttatcgtagg atttcacctt tttactacct tctatcctat
    21781 ttctgattca ctgttaacag atttcttgaa agcttttaca gaacaaagaa tccttgctat
    21841 tgtattcgtt cttattcttt gctttatatt tttcggttca atttattact gtatttcatg
    21901 tggacgaaat agaaaattga tacctgataa agtttataca caaatcacaa cttacatttc
    21961 atctgtaggt ttagggactg cagtgatagc tgtcgctacc ttgactctca cagaattaca
    22021 gttttcaatc cttacaggtt ggattgcttt tatcgctttg ttgttgccac ttctgaagtt
    22081 taaagtccaa tacagcacct atcaaagtag cgacaatgta gcacagaaaa ctaccgaaaa
    22141 caaagccaat taagaaaggc tctaccattc tcctctcccc ctttctttta aaaaattatc
    22201 taaaaagtta gcgaattcct tgacaaaaaa caatctatag tttagaattt aatcatagag
    22261 aaaagaccta ctaaaagtaa ggttctacct agaaaacgga cgccaatcag tttcattagg
    22321 ctttattttt tagttgtctt gttcgctaac tctttagctt acaaataata ttctaaacta
    22381 tagattgcat tttgtcaaca gatttacaat caaaagttta aatatttttt gtcatgcctt
    22441 agaaaggttg ataaatcaat gttttcttta ttcgaaaaaa taaaagaact ttgccaaaat
    22501 cgtggaattt ctataaattc tcttgaagaa acattaggat atagtagaaa tacaatctat
    22561 agtatgaaaa acaaaaaacc aaatgctgaa cgtcttcaag aaattgctga ctacttcaac
    22621 gtgtccacag attatttact tggtcgcacg gataatcctg ctattgctgg tgattcaaaa
    22681 gagtacactt ggcaagggaa gaccctaaat gttgaagaaa tggcatctaa tgtcatgatg
    22741 tttggcggcc gagaattaac agatgaaaag aagaaaatca tccagtctat cattgaaggt
    22801 tatctcaaag aagctggtga ttagaggtac tgcttagtga ccgaaaaaga aattataagt
    22861 cattttcagg ttcgcattgt cgattttgac ggtgagctaa tacctgatga acttggattt
    22921 tacgaaaaag aaaccaacac agctttcttg tctaacaaac tcagcaaaaa agagagagtt
    22981 aaggtactat tgcatgaact cggacacaaa gaccacacac gctcagagta ccagaacgct
    23041 cgcctacgct gtgaaaacga agctgatagg aatatgatcc atcatctcgt aaaagacgca
    23101 ctagaaagct tagacgaccc cacagagttt gattacctca aattcatgtc ttattacaat
    23161 cttaaaactg tgactaatga agtcatggtc aaggaagagt acttggcatt agtaaattaa
    23221 aaattgcatt gaagatattt atatagaggg gaaatatatg caaaagactg ttgaaaaaat
    23281 attattcaga gtcgctggag tgacaaaata taaaaaagca gtaaaagaag cttgcaatat
    23341 gattgctgaa gacaatggga ttccagagta ttcaaaatac tatggcgatt tatcagctaa
    23401 ggaaatcagg gaagaagttg aagaatacgg tctaaaagtt tttaaatatc gagatttaga
    23461 tatttttaat attgaactca ttccagaaac ggataataaa tatgatccca atgctataaa
    23521 agttttgatt tttgataatc acataggata cgtccctgca acagtctcta aatctattcg
    23581 taaatatttt gatgatgaaa gatatcattt cctaatagaa tgtgagataa aaggcggccc
    23641 atacaaagaa tgggacgatt atgaagaaaa agttgtcata aataatgatt tggatgttgg
    23701 ttttgaaatt taccttacca ttgttgattc ttcacaaaaa gaagtaattc agagcgaatc
    23761 atctgagata attgatgata acattttcaa taaagaagtt acgaaaactg aatctattga
    23821 aactaaaaca actgaagctg aacatattga acaaaatatt gttagtgata gtttcgctga
    23881 tatagtaaac gagattaatc tttcagaaac atctcctaag aaaaaacttc ctgccaataa
    23941 aatcatattt tcagcactgt atcttttctt agtctttttt ggagttgttg gtattccaat
    24001 cgctccattc cttgcagtcc ctttgacagc ttggagtttg tataaactat acaaactatt
    24061 cagaaaataa aaaaaagccc cacaatcgcc ctcgccaaag tttgattgtg aagcttacct
    24121 tgtataaaaa tcagccatta aaaaggcctc ttttctatac cctattttac accatgaaag
    24181 gggtgatgtc aatattctca atgtttagac cttgtccaga agcctgtaaa caaggagaat
    24241 acaatgaaat ataataaaac aaaataccca aatatctatt actatgagac tgctaaaggc
    24301 aagcgttact atgtcagacg ttcttttttc ttccgaggta aaaaaagaga aaaaagtaaa
    24361 agtggtttca caactctccc tcaagctcgt gcagccttgg tagagcttga gcaacaaatc
    24421 caagaacaag aattaggtgt caatacgaat ctgacacttg atcaatattg ggatatttat
    24481 tctaaaaaga gattgtcaac agggcgctgg aatgacactt cctactacct caatgataac
    24541 ctctataaga atcatatcaa aaccaaattt ggttctattc agcttaaaaa tttggataga
    24601 aatgagtatg aactctttat cgctgaaaag ttgcagaacc ataccagata cactgttcaa
    24661 accctcaatt ccagcttcat ggcattgctg aatgatgccg tgaaaaatgg taatctgctc
    24721 tcaaatcgct tgaaaggtgt tttcatcggc cagagtgata tccctgctgc aaacaagaaa
    24781 gtgactctca aagagttcaa gacttggata gcaaaggcag aagagattat gccaaaacaa
    24841 ttctacgctc tgacctatct gacaattttt ggattgagaa gaggagaagt ctttggattg
    24901 cgtccaatgg acatcactca gaacgacagc ggacgggcta tactgcatct tagagacagt
    24961 cgaagcaacc agaccttaaa agggaaagga gggcttaaaa cgaaggattc agagcgatat
    25021 gtctgccttg atgatatcgg aacagacctg atctattatc tgatagctga agcttctaag
    25081 attaagcgaa agttaggaat tatcaaggaa cagcacaagg attatataac tatcaacgag
    25141 aaaggtggtc tcatcaatcc aaaccagcta aatagaaact tcaatctagt gaatgaagca
    25201 acaggattgc atgtaacacc tcacatgatg cgccacttct tcacgactca aagcattatt
    25261 gcaggggttc cgcttgaaca attaagccag gcgctgggcc atacaaaagt ctatatgacc
    25321 gatcgttaca atcaagtaga ggacgaactt gctgaagcga caacagacct atttcttagt
    25381 catattcgct aaaaaaatcc ccgccaattc cccgaccaaa atccgaaaaa taccga
//
LOCUS       DAVDHC010000028        24804 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVDHC010000028 DAVDHC010000000
VERSION     DAVDHC010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24804
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.028"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            436..1146
                     /gene="deoD"
                     /locus_tag="VUR43_001634"
     CDS             436..1146
                     /gene="deoD"
                     /locus_tag="VUR43_001634"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET5413295.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1169..1693)
                     /locus_tag="VUR43_001635"
     CDS             complement(1169..1693)
                     /locus_tag="VUR43_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET5413296.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWGIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1746..1982)
                     /locus_tag="VUR43_001636"
     CDS             complement(1746..1982)
                     /locus_tag="VUR43_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET5413297.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(2050..2970)
                     /locus_tag="VUR43_001637"
     CDS             complement(2050..2970)
                     /locus_tag="VUR43_001637"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET5413298.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYCHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3160..3564
                     /locus_tag="VUR43_001638"
     CDS             3160..3564
                     /locus_tag="VUR43_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413299.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFICSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            3780..4361
                     /locus_tag="VUR43_001639"
     CDS             3780..4361
                     /locus_tag="VUR43_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5413300.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGEKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4358..5635
                     /locus_tag="VUR43_001640"
     CDS             4358..5635
                     /locus_tag="VUR43_001640"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET5413301.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSDIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5653..6315
                     /gene="deoC"
                     /locus_tag="VUR43_001641"
     CDS             5653..6315
                     /gene="deoC"
                     /locus_tag="VUR43_001641"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET5413302.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6302..6691
                     /locus_tag="VUR43_001642"
     CDS             6302..6691
                     /locus_tag="VUR43_001642"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET5413303.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAVFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLS"
     gene            6781..7833
                     /locus_tag="VUR43_001643"
     CDS             6781..7833
                     /locus_tag="VUR43_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET5413304.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7977..9512
                     /locus_tag="VUR43_001644"
     CDS             7977..9512
                     /locus_tag="VUR43_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5413305.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKIESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            9505..10563
                     /locus_tag="VUR43_001645"
     CDS             9505..10563
                     /locus_tag="VUR43_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5413306.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10566..11522
                     /locus_tag="VUR43_001646"
     CDS             10566..11522
                     /locus_tag="VUR43_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5413307.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            11607..12878
                     /locus_tag="VUR43_001647"
                     /pseudo
     CDS             11607..12878
                     /locus_tag="VUR43_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(12921..13562)
                     /gene="plsY"
                     /locus_tag="VUR43_001648"
     CDS             complement(12921..13562)
                     /gene="plsY"
                     /locus_tag="VUR43_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET5413308.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            13698..15641
                     /gene="parE"
                     /locus_tag="VUR43_001649"
     CDS             13698..15641
                     /gene="parE"
                     /locus_tag="VUR43_001649"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET5413309.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KVGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            16061..18532
                     /gene="parC"
                     /locus_tag="VUR43_001650"
     CDS             16061..18532
                     /gene="parC"
                     /locus_tag="VUR43_001650"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET5413310.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            18664..19686
                     /locus_tag="VUR43_001651"
     CDS             18664..19686
                     /locus_tag="VUR43_001651"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET5413311.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPSSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WSVKVD"
     gene            19742..20446
                     /locus_tag="VUR43_001652"
     CDS             19742..20446
                     /locus_tag="VUR43_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5413312.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNIAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGDPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            20511..21200
                     /locus_tag="VUR43_001653"
     CDS             20511..21200
                     /locus_tag="VUR43_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET5413313.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            21197..22120
                     /locus_tag="VUR43_001654"
     CDS             21197..22120
                     /locus_tag="VUR43_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET5413314.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            22135..22779
                     /gene="pcp"
                     /locus_tag="VUR43_001655"
     CDS             22135..22779
                     /gene="pcp"
                     /locus_tag="VUR43_001655"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET5413315.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            22947..23177
                     /locus_tag="VUR43_001656"
     CDS             22947..23177
                     /locus_tag="VUR43_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET5413316.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            23227..23307
                     /locus_tag="VUR43_001657"
     tRNA            23227..23307
                     /locus_tag="VUR43_001657"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23261..23263,aa:Tyr,seq:gta)
     gene            23317..23388
                     /locus_tag="VUR43_001658"
     tRNA            23317..23388
                     /locus_tag="VUR43_001658"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23349..23351,aa:Gln,seq:ttg)
     gene            23550..24752
                     /gene="rpsA"
                     /locus_tag="VUR43_001659"
     CDS             23550..24752
                     /gene="rpsA"
                     /locus_tag="VUR43_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET5413317.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT         7459 a         4373 c         5619 g         7353 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaataaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaccccacc
      181 ctaaaagcag tgggaaaaag atagttggtc tagcgagcat cgctcactgc gcccaactcc
      241 tattttccct tcgctttttg atgggtttgg tatctttctc aatataaaat ataaaataaa
      301 gaaaggtaga gcgtgtgttt tgatttgaac acgagcggaa aactcggaaa atagataatc
      361 tgactgaaaa atcaggattt ctcgtcaggt tcctaatttt cagtcgtttt cttctcgctc
      421 tttgtatcat aaattatgtc tatccatatt gctgctcagc agggtgaaat tgctgataaa
      481 attcttcttc ctggggatcc tcttcgtgct aagtttattg cggagaattt ccttggtgat
      541 gctgtttgtt ttaacgaagt gcgtaacatg tttggttaca ctggtactta caagggtcac
      601 cgtgtatctg tcatgggaac tgggatggga atgccatcta tttcgattta tgcgcgtgag
      661 ttaatcgtag actacggtgt gaagaaattg attcgtgtgg gaactgcagg ttctttgaat
      721 gaagaggttc atgttcgtga attagttttg gcgcaggcgg ctgcaaccaa ctcaaacatc
      781 gttcgtaatg actggccaca gtacgatttt ccacaaattg ctagctttga tttgcttgat
      841 aaagcctacc atatcgccaa agaacttggt atgactactc acgttgggaa cgttttgtca
      901 tctgatgtct tttactcaaa ttactttgaa aagaatatcg agcttggtaa atggggagtc
      961 aaggctgtgg aaatggaagc agcagctctt tactatcttg ctgcccaata ccatgttgat
     1021 gcgctagcta tcatgaccat ctctgatagc ttggtcaatc cagacgaaga cacaactgca
     1081 gaagaacgtc aaaatacctt cactgatatg atgaaggttg gtttggaaac cttgattgca
     1141 gaataattat agccaaaaag gaagcccttt atgaattgta ggacttcctt ttcttatcca
     1201 gaaattgatc tagctctctc tgatttcgaa gaatagtgac tttatgtgaa tattcttggc
     1261 aaagtttttg gtaattttct ttttgagttt tgctacgccc atcccaaaga atccatctga
     1321 taaactccca gtcaaagcgt tcagggcaat ctgccgccat actttctctg acttttccac
     1381 ggtatttaag ataacgctta aaggctctaa agagacaggt caatggcaaa aaattgagaa
     1441 agatgatttg gtcagcttct tgcattcgtt cttggtagta gcaccaagaa taattaccat
     1501 cgatgcccca agctttatgc ttggtgagaa agttttttat ctcggttaac atccattcgc
     1561 agtcactgtc ttgccaacca ggttgaaatt ggagtgtgtc catgtgcagt tttggaatgg
     1621 agtagtagtt agataacttt tctgctagag ttgacttacc agaaccagaa tatccgataa
     1681 ttgtgatttt cattttctac cttttcctat ttggagacaa aaaaacagcc tctatggact
     1741 gtttcttatt tagcaagttt agctgaaaga cgagctttat cgcggcttgc tttgtttttg
     1801 tgaatcaaac ctttagtttc tgctttatcg atagctgagc tagcagcacg gaaaagttct
     1861 tcagatgggt ttgcttcgaa agcttttata gcagtacgca tagctgattt ttgagctgag
     1921 ttcttttcgt tttgtttaac gttcaattca gcgcgtttga tagctgattt aatgtttgcc
     1981 aatgttctta cctccatatt tactaactat accattatat atgaaaactt acgttttgac
     2041 aagggaaaat tattttttta agtaaatttc atcgatttca tggttcttgc ttttatgaag
     2101 aatcacttct gcacgatttc tggttggttc aatataattt tgtagatttg tgagattgat
     2161 actggtccag acctgatggg caaaggcttc cacttcccca atcggcatct gagtaaaacg
     2221 ataatagtag ctatcagggt cgttttgggc tagactcagc attttcaaga aacggtccag
     2281 ataccaactt tcaatatcat ccactccagc atctacatag atggaaaagt caaagaagtc
     2341 agtgatatag agacgatcgt tttgtggatt ttgaaagaca ttgattccct caacaattac
     2401 aaaatcagca gctttgacac tttgtttctc ttcgggtacg atgtcgtaaa cttcatgaca
     2461 atagacagga atatctacat cttgtccatt tttgatgcgg tccaagaagt tgagaagagc
     2521 ttccatatca tagctttcag gaaatccttt acgatttaaa atcccctgct caatcaaggt
     2581 ttgattggga tagagaaaac catcagttgt aaccaactca accgtagcat ctgtaaacgt
     2641 acgggacagt aggatttgaa gtaggcgact ggttgtggat tttccaacgg caacactccc
     2701 agaaacccca ataataaaag gttgagattt actttcacgt tggaggaaaa ttccttttga
     2761 aaaggctaaa tcttccttag ttcgcttgta aatctgaatc agatgagcca aggggagata
     2821 gatatctgta acgtcttgga gactgatttg gtcattaaaa ctcttgatag attccaattc
     2881 ttcttctgtc aaaggaggtg ttgtctttcg atgtaaagat tgccaagtct ggcggctgat
     2941 tttttcaaaa tgtaaaaatt cgttggtcat ttgttttccc ctaggtattt tatctatcat
     3001 accataaaaa gctaaaaaaa taaagcggtt tcttgaatgt tgtaagtcaa tgatatataa
     3061 tataagcgat caatttattg atgaaatagg agatagattc tactgattta taagcttata
     3121 aagggggctt tttagttcac aacttatagg aggtgtacta tgaaaatctt aaaacgttac
     3181 atattggaac tctgttttat tttaagtttt gctttacctt ttataaaagg agccaatgca
     3241 gataatggta gatgctttgt ggaaacctat tacggtttta cttttttgat ggaacatgct
     3301 attgtaacag ctgtctttat ctgttcgttt ttaattgctt tcttactaaa aaaacgatgg
     3361 gcgaaatgga ttgctgctgg tagttattgc tttttagtcc tatggattgc gacagagggt
     3421 tatttcttcc gcatgtcact agaagatttg atacgacttt ggacaagttt ggaaatcctg
     3481 acacaaacgt atcagttggg cttttatcta aacattttgt tgggaatttt gttgataata
     3541 aagtatttta aggttaagca atagaaataa taatctgcct gattatagat gataaacttt
     3601 ttgtttttat ctggactgtg atatttatag ttctaaatgg tttattattt ataagtgttg
     3661 aaagagattg aagaaaatgg cttcgtgact cgctttcttc ggtctttttc gttttattat
     3721 caatttgtaa acgatttaca atttgagtca aattatggta aaatagtgtc atgagtaaaa
     3781 tgtattatgc agaaaatcct gacgctgctc acgacattca tgagttgaga gtagacttgt
     3841 tgggagaaaa aatgactttt ttgacagatg cgggtgtttt tagcaagaaa atagttgact
     3901 ttggaagtca actattgctc aagtgtcttg aggtcaacca aggagaaact gtccttgatg
     3961 taggctgtgg ttacggacct ttgggtttgt ccttagctaa ggcttatgga gttcaggcta
     4021 ctatggttga tatcaacact cgtgccttgg atttagctcg gagaaatgct gaaaaaaata
     4081 atgcaaaagc gacgattttc cagtccaaca tctatgaaca agttgaagga cattttgatc
     4141 atgtcatttc caatcctcct atccgtgcgg gcaagcaagt cgttcatgaa atcattgaga
     4201 aaagtaaaga tttcttggaa actggtgggg atttgacaat cgtcatccag aaaaaacaag
     4261 gggctccaag tgctaagtcc aagatggagg atgtgtttgg taattgtgaa atccttaaaa
     4321 aagacaaagg atactatatc cttagaagtg tgaaagaatg agagcagttg atttaataca
     4381 aaaaaaacga gacggtcaag aactgacttc aagtgaaatt gaatggctgg tagaaggcta
     4441 tgtgtcagga actgttcctg attatcagat gtctgccttt gctatggctg tttattttaa
     4501 aggaatgacg actcgtgaaa tttctgattt aacgatgaat atggttaaga ctgggcaaga
     4561 gtttgacctg tcagacattg atggtgtgaa agttgacaag cattctactg gtggtgtcgg
     4621 cgataaggta accttgattt tagctcctct tgttgctagc ttcggtgtgc ctgtagcaaa
     4681 aatgagtggt cgtggtcttg gccatacagg cggaacaatt gataaattgg agtccattag
     4741 gggctatcaa gtagaacgta gtcaagagga ttttattcgt caggttcagg atattggagt
     4801 atctgtcatt gggcaatcag accagctggt caaagcagat aagcttctct atgcccttcg
     4861 tgatgtgacc gcaactgtcg acacgattcc tttgattgcg agttcggtga tgagcaagaa
     4921 aattgcggca ggggcggatg ctattttgct agacgtgact gtcggtgagg gtgccttcat
     4981 gaagacggtt gatgaggcgc gtgagttggc tcaaactatg gtagatcttg gtaaggttgt
     5041 tggacggaag acagtagcag tgattacgga tatgagccag cctttgggac gagcgattgg
     5101 aaatcgtctg gaaatacttg aagcattgga gattttgcaa ggtcaaggac gtcaggatat
     5161 tacccacttt atttgtgaat tggctcaaat tatgcttggt ttggcaaatg ttaacaagac
     5221 tgttgaagaa gttcaccaac atcttgagaa tggtcaagca ctggctaagt ttgaggaaat
     5281 ggtgcaagcc caaggtggag acttggaaga cctctatcgt cctgtaaatg tagctcatgt
     5341 ggtggaaatc cctgctcagg aaacgggtgt catttcagct cttccagcta tggactttgg
     5401 tctttatgcc atgaggctgg gtgctggtcg tgcagttaag tctgatgcct tggactatga
     5461 aacaggaatt gtttttgaaa agaagattgg agactccgtt caaaagggtg aaattgttgc
     5521 aaaagtatac acaaatgaaa aaattccacc tcaactagtt acagatttcc aaaaatgtgt
     5581 taaaataagt gatgaagtga aaaaaatccg tgaaattgta gaaatcatct cctaaatgga
     5641 gggaaaaccg aaatgaaatt aaataaatat atagatcata cgcttttaaa acaagatgca
     5701 aagaaaaaac aaattgatag tttgttgtct gaggctagag agtatgactt tgccagtgtt
     5761 tgcgttaatc cgacctgggt tgaacatgct aaaaaaggac ttgaaggcac agatgttaag
     5821 gtttgcacag tagtaggttt ccctttggga gcaacaactt cagccgtgaa agcatttgag
     5881 acaaaagaag ctatccaaaa tggtgcagat gagattgata tggtgatcaa tgttggggct
     5941 ctcaagtcag gtgatttggc cttggttgag tcagatattc gcgcagtagt ggaagcaagt
     6001 ggtgataagt tagtgaaagt cattattgaa gcttgccttc tgacagacca agaaaaagtt
     6061 gttgtttgcc aattggccca aaaagctggg gctgactttg tcaaaacatc tactggcttt
     6121 tcaactggtg gtgctacgat agcagatgtt acattaatgc gtgaaacagt tggatctgat
     6181 atgggtgtca aggccgccgg tggagctcgt tcttatgcag atgctcttgc ctttgtcgaa
     6241 gcaggtgcga cccgtatcgg aacgtcagct ggggtagcta ttttaaaagg agaattggca
     6301 gatggcgact actgagttga ttgaactggc aattgaaacc agcaaacatg cctatgtccc
     6361 ctattctcac tttcctatcg gagcagtttt agtagctaaa gacggaagtg tttacacagg
     6421 agtgaatatc gaaaatgcta gctatccttt gaccaattgc ggtgagagaa cagcagtttt
     6481 taaggctata tctgaaggcc aaagagaatt ttcagaattg attgtctatg gtcaaactga
     6541 aaaaccgatc tcgccatgtg gtgcttgtcg ccaagtgatg gctgaatttt ttgaacaaga
     6601 tctaaaagtg accttagtcg caaaagataa atcgacggtc gagatgacgg tcggggaatt
     6661 acttccatac tcttttacag acttaagcta gtctgagtcg ctctctgagt ggcacggtcc
     6721 ttgtggccaa ccaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta
     6781 atgaacaaga aacaatggct aggccttggt ctagttgcag tggcagcagt tggacttgct
     6841 gcatgtggta accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca
     6901 gcaatcgtca ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa
     6961 ggtttgcagg cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc
     7021 caatcaacaa gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac
     7081 ctaatctttg gtgttggttt tgcccttcat aatgcagttg aagaagcagc taaagaacac
     7141 acagacttga actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc
     7201 gtaactttcg ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact
     7261 aagacaaaac aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa
     7321 gcaggattca aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac
     7381 gctggttcat ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc
     7441 ggtgcagata ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca
     7501 aaatctctca acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgatcgt
     7561 gaccaagaag cggaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt
     7621 gtatctactt tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa
     7681 ggagaattcc ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg
     7741 gcagtaacaa acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc
     7801 cttgatggaa gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg
     7861 gccaagggcc gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta
     7921 ctagacaaac tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg
     7981 cacacgaaaa tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca
     8041 acgacaaaat caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg
     8101 gggctggtaa gtccacgcta atgaacatgt tagcaggcct tcttgaacca actagtggtg
     8161 aaatcgcggt caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg
     8221 gaatcgggat ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca
     8281 tcattttagg tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag
     8341 aaatcaaggc tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag
     8401 atatctcagt tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg
     8461 atatccttat ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga
     8521 tggctattat gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat
     8581 tggatgaaat tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg
     8641 aaaccgttga aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtaggacgtt
     8701 ctgtttcctt taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca
     8761 aagatttggt ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg
     8821 ttcgtgctgg agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga
     8881 ttcaagccat tacaggtctt cgtaagattg aatctggtag cattgagcta aaaggagatt
     8941 caattgtagg cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag
     9001 accgtcaccg tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa
     9061 cctactataa agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt
     9121 atgctaaaaa gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag
     9181 ctgcactctc aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc
     9241 ctgatctcct tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata
     9301 tccacaaacg cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg
     9361 aattggatga gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc
     9421 aaggtattgt atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg
     9481 gaaacttggg aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg
     9541 atttctgtat ttctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat
     9601 gctatttggg gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga
     9661 gaaatcttcc gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt
     9721 cgagctggtt tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt
     9781 ggttggtttg cgctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc
     9841 gtgattgcct tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat
     9901 ctagggacgt cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg
     9961 aatgccttta tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt
    10021 gttggggcta atgcaaccta tcagacacct tggttggctg agttgactgg taactcacgg
    10081 atgaatattg gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag
    10141 aaaacaactc ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat
    10201 gctggtattt ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca
    10261 ggtcttggtg gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg
    10321 tcattagcta tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt
    10381 ggtatactct ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat
    10441 gcggcgcagg taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc
    10501 agtgttcatt accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag
    10561 taaagatgtc tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag
    10621 cacctctcat ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg
    10681 ttggccttga aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat
    10741 ttgcagaaca atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg
    10801 gtagtgtttt ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg
    10861 tcagcggtac ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc
    10921 tttataacaa aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag
    10981 tcttggcaaa tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt
    11041 atctggcgat tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc
    11101 ttcgtctccg ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct
    11161 acaagatgag atatttaggg attattattt caggttttct aggtggaatt ggcggagcga
    11221 tttatgcgca atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta
    11281 tcgcccttgc tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc
    11341 tcttctttgg actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag
    11401 gagtgccagc ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag
    11461 ccttctttgg aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat
    11521 aagcatacaa aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa
    11581 aatctaactt ttggggtgtt tttattatga aattaagtta tgatgataaa gttcagatct
    11641 atgaacttag aaaacaagga tataacttag agaagctttc aaataaattt gggataaaca
    11701 attctaatct taggtatatg attaaattga ttgatcgtta cggaatagag ttcgtcaaaa
    11761 aagggaaaaa tcgttactat tctcctgatt taaaacaaga aatgattaat aaagtctgac
    11821 atgaaggctg gactaaagat agagtttctc ttgaatacgg tctcccaagt cgtacgatac
    11881 ttcttaactg gctagcacaa tacaggaaaa acgggtatac tattgttgag aaaacaagag
    11941 ggagagtacc tgagagcgga gaatgccatc ctaaaaaagt taagagaact ccgattgaag
    12001 gaggaaaaag agaaagaaga aagacagaaa ttgtttaaga attaatgact gagttttcgt
    12061 tagatattct tctaaaagcc attaaactag ctcgttcgac ctactactat cacttgaaac
    12121 agctagataa accagataag gaccaagagc ttaaagctga aattcaatcc atctttatcg
    12181 aacacaaggg aaattatgct tatcgtcgga tttatttaga actaagaaat cgtggttatc
    12241 tggtaaatca taaaagagtt caaggcttga tgaaagtact caatttacaa gctaaaacgc
    12301 gacagaaatg aaaatattct tctcataaag gagacgttga taagaaagca gagaatctca
    12361 ttcaaggcca atttgaaggc tctaaaacaa tggaacagtg ctacacagat gtgactgaat
    12421 ttgccattcc agcaagtact caaaagcttt acttatcacc agttttagat ggctttaaca
    12481 gcgaaattat tgcttttaat ctttcttgtt cgcctaattt agaacaagta caaacaatgt
    12541 tggaacaggc attcaaagag aagcactacg agaatacgat tctccatagt gaccaaggct
    12601 ggcaatatca acacgattct tatcatcggt tcctagagag taagggaatt caagcatcca
    12661 tgtcacgtaa gggtaacagc ccagacaatg gtatgatgga gtccttcttt gggattctga
    12721 aatcggaaat gttttacggt tatgagaagt cgtttcagtc gtttaagcaa ttggaacaag
    12781 ctattgtaga ctatattgat tactacaaca acaaacgaat taaggtaaaa ctaaaaggac
    12841 ttagtcctgt gcagtacaga actaaatcct ttggataaat tatttgtcta actgtttggg
    12901 ggcagtacag aactggcgtt ttatttttta ggatcttgat gagttaggtt caatccccaa
    12961 gggaccaaat tttcagtttt atttttgata cgagctatat tgtccttatg acgaatgata
    13021 atcaaactag caagtgctaa gataatagcg atgaagagag agtcatagtt actcaggata
    13081 aaaccaaaaa gtggaaagag cagaaccccg ataacagccg cgatcgatgc tgtgacacta
    13141 gacagtgaaa tcatactgcc aagatagaga gctccaaaga agataatcgc aaggtagaga
    13201 cagaagatag gcgcaaatcc gaaaatcact ccagcactgg ttgcgacagc cttaccacct
    13261 ttaaatcctg caaagatagg gaaggtatgg ccgataacag ccaaaagtcc aaagatgaga
    13321 ggagaaacgc cttgtagatg aaaaataatc ggaagcagcg ttgctagggt tcctttgaaa
    13381 aagtcaatca caaaggttgc cataccagct ttcttaccta aaatgcggaa ggtattggtc
    13441 gttccagtgt taccagaacc atgctcgcgt agattgattt gaaagaatac ttgtccaatc
    13501 cagagaccag atggaatcga acccagcaga taggctagga ttaataaaac tattgtaatc
    13561 atactcctat tatatcatga attgggaaag aaaagcagag aatctctgct aaaattgtca
    13621 catcggagaa agaaaaattt tgcaaaatcc ttggaaaacc tgtagaatag taaagatgaa
    13681 cgaataggag gttccttgtg tcaaaaaagg aaatcaatat taacaattat aatgatgatg
    13741 ctattcaggt gctagaaggg ttggatgcgg tccgaaaacg tccagggatg tatattggat
    13801 cgaccgatgg cgctggtctt catcacctag tttgggaaat cgttgataat gcagtcgatg
    13861 aagccttgtc tgggtttggt gatcgtattg atgtaactat caataaagac ggtagtctaa
    13921 cggttcaaga ccatggacgt gggatgccga caggtatgca cgctatggga attccaactg
    13981 ttgaggttat ctttaccatt cttcatgccg gagggaaatt cggtcaaggt ggctataaga
    14041 catcaggtgg acttcacgga gtgggttctt ccgttgttaa cgccctttct agctggttag
    14101 aagttgaaat tacccgtgat ggcgcagttt acaagcaacg ttttgaaaat ggtggaaaac
    14161 ctgtcacgac tttgaagaaa gtcggtacag cacccaagtc taaaacaggc accaaagtta
    14221 cttttatgcc tgacgcgact atcttttcta cgacagattt caagtacaat accatttcag
    14281 agcgccttaa tgaatcagcc tttctcttga aaaatgtgac cttgtcttta acggacaagc
    14341 gaacagatga agcgattgag ttccactatg agaatggagt acaagatttt gtttcttatc
    14401 tcaacgaaga taaggaaatc ttgacgccag ttctttactt tgaaggggaa gacaatggtt
    14461 ttcaagtgga agtagccctc cagtacaatg acggattctc agataacatt ctatcctttg
    14521 tcaataacgt tcgcaccaag gacggtggaa cgcacgagac aggactcaag tctgccatta
    14581 ccaaggtcat gaatgactat gcacgtaaaa caggtcttct caaggaaaaa gataaaaacc
    14641 ttgaaggttc agactatcgt gagggactag cggccgttct ttctatctta gttcctgaag
    14701 aacacttgca gtttgaagga cagaccaagg ataaactagg aagcccccta gctcgcccag
    14761 ttgtggatgg aatagtggct gataagttga cctttttcct tatggaaaat ggggaattag
    14821 cttctaacct catccgcaag gctatcaagg cccgtgatgc tcgtgaagca gcacgtaagg
    14881 cgcgtgatga gagccgaaat gggaagaaaa acaagaaaga taagggcttg ttgtctggga
    14941 aattgacccc agcccaatct aagaatcctg ctaagaatga actctatcta gttgaggggg
    15001 actctgccgg tggttctgcc aaacaaggtc gtgaccgcaa gttccaggct attctacctc
    15061 ttcgtggtaa ggttatcaat acagccaagg ccaagatggc ggatatcctc aaaaatgaag
    15121 agatcaatac catgatttat accattggtg cgggtgttgg agcagacttc tctattgaag
    15181 atgccaacta tgataagatc attatcatga ccgatgcgga taccgacggt gcccatatcc
    15241 agaccttgct cttgacattt ttctaccgtt acatgcgtcc gctagtcgag gcaggtcatg
    15301 tctatattgc cctcccacct ctttacaaga tgtccaaagg taaaggcaag aaagaagaag
    15361 tggcctacgc ttggacggac ggagaactag aagaactccg taaacagttc ggtaaaggcg
    15421 ctaccctcca acgatacaaa ggacttggtg agatgaatgc ggaccagctc tgggaaacaa
    15481 ccatgaaccc agaaacacgt accctcatcc gtgtcacaat tgaagattta gcgcgcgccg
    15541 aacgccgcgt caatgttctc atgggagata aggtagaacc acgccgtaaa tggattgaag
    15601 ataatgtcaa gtttacgcta gaagaagcga cagtgtttta atgaaagaaa ataatatgtt
    15661 agtaaactgg aaattagagt cggatgtgaa tgactatgtg aaaaagcagt ttgaaaatct
    15721 tggtttgaaa aaattgcagg attattaatg aaggatctgc tatgagtgct tatcttaaag
    15781 aggcgcttaa gggagcggtt aagacacaaa ctaagactaa ttttggaaaa ccagattttc
    15841 atattgaaaa atacaaacag gatagtttgg ttacttatcg taactgaaca cgggacgaat
    15901 tcccgtaaaa tatcttttac tgcataaaaa cctactctac attctttgaa aggagttgaa
    15961 cacgccctag atactgtgtg aaaaagataa attctcttgt gagtttgctt acttcaagaa
    16021 ttttctattt tcacttggta ttttatgggc tttgtatctt atgtctaaca ttcaaaacat
    16081 gtccctggag gacatcatgg gagagcgctt tggtcgctac tccaagtaca ttattcaaga
    16141 ccgggctttg ccagatattc gtgatgggtt gaagccggtt caacgccgta ttctttattc
    16201 tatgaataag gatagcaata cttttgacaa gagctaccgt aagtcggcca agtcagtcgg
    16261 gaacatcatg gggaatttcc acccacacgg ggattcttct atctatgatg ccatggttcg
    16321 tatgtcacag aactggaaaa atcgtgagat tctagttgaa atgcacggta ataacggttc
    16381 tatggacgga gatcctcctg cggctatgcg ttatactgag gcacgtttgt ctgaaattgc
    16441 aggctacctt cttcaggata tcgagaaaaa gacagttcct tttgcatgga actttgacga
    16501 tacggagaaa gaaccaacgg tcttgccagc agcctttcca aacctcttgg tcaatggttc
    16561 gactgggatt tcggctggtt atgccacaga cattcctccc cataatttag ctgaggtcat
    16621 agatgctgca gtttacatga ttgaccaccc aactgcaaag attgataaac tcatggaatt
    16681 cttacctgga ccagacttcc ctacaggggc tattattcag ggtcgtgatg aaatcaagaa
    16741 agcttatgag actgggaaag ggcgcgtggt tgttcgttcc aagactgaaa ttgaaaagct
    16801 aaaaggtggt aaggaacaaa tcgttattac tgagattcct tatgaaatca ataaggccaa
    16861 tctagtcaag aaaatcgatg atgttcgtgt taataacaag gtagctggga ttgctgaggt
    16921 tcgtgatgag tctgaccgtg atggtcttcg tatcgctatc gaacttaaga aagacgctaa
    16981 tactgagctt gttctcaact acttatttaa gtacaccgac ctacaaatca actacaactt
    17041 taatatggtg gcgattgaca atttcacacc tcgtcaggtt gggattgttc caatcctgtc
    17101 tagctacatc gctcaccgtc gagaagtgat tttggcgcgt tcacgctttg acaaagaaaa
    17161 ggctgagaaa cgtctccata tcgtcgaagg tttgattcgt gtgatttcga ttttggatga
    17221 agtcattgct cttatccgtg cttctgagaa taaggcggac gccaaggaaa acctcaaagt
    17281 tagctatgat tttacggaag aacaggctga ggctatcgta actttgcaac tgtaccgttt
    17341 gaccaatacc gatgtggttg tcttgcagga agaagaagca gagcttcgtg agaagattgc
    17401 tatgctggcg gctattatcg gtgatgaaag gactatgtac aatctcatga agaaagaact
    17461 tcgtgaggtc aagaagaaat ttgcaactcc tcgtttgagt tctttagaag acactgcgaa
    17521 agcaattgag attgatacag ctagtcttat cgctgaggaa gatacctacg tcagcgtgac
    17581 caaggcaggt tacatcaagc gtaccagtcc acgttccttt gcggcttcca ccttggaaga
    17641 aattggcaag cgtgatgatg accgtttgat ttttgttcaa tctgccaaga caacccagca
    17701 cctcttgatg ttcacaagtc ttggaaatgt catctacaga ccaatccatg agttggcaga
    17761 tattcgttgg aaggacatcg gagagcatct gagccaaacc atcacaaact ttgaaacgaa
    17821 tgaagaaatc ctttatgtgg aagtactgga tcagtttgac gatgcgacaa cctactttgc
    17881 agtgactcgc cttggtcaaa tcaaacgggt agagcgaaaa gaattcactc catggcggac
    17941 ctatagatct aagtctgtca agtatgctaa gctcaaagac gatacagatc agattgtagc
    18001 agtggctccg attaaactag atgatgttgt cttggttagt caaaatggtt atgccctgcg
    18061 tttcaatatc gaagaggttc cggttgtcgg tgctaaggca gcaggtgtca aggctatgaa
    18121 tttgaaagaa gatgatgtcc tccaatctgg ctttatctgt aatacttcgt ccttctacct
    18181 cttgacccag cgtggaagct tgaaacgtgt ttccattgag gaaattctag caaccagccg
    18241 tgccaaacga ggattacaag tcttgcgtga gttgaaaaac aaaccgcatc gtgtcttctt
    18301 ggcaggagca gttgcagagc aaggatttgt tggcgatttc ttcagtacgg aagtggatgt
    18361 gaacgaccaa actctgcttg tccaatccaa taaaggaaca atctatgaaa gccgattgca
    18421 agacttgaac ttgtcagaac gcactagcaa tggaagcttc atttctgaca cgatttcaga
    18481 tgaagaagtt tttgacgctt atcttcagga agtagttact gaagataaat aagtgaaatg
    18541 aagaatcagt tctaagagtt ggtttttatt ggagaaattt tctgaaaatt acaaaatatg
    18601 cttgctattt tagaaaaata gtgtagaata taagaaatag gtttttagaa taaggagtgg
    18661 aatatgacag taacgattga ttgggaaaac ctcggttttt cctatatgaa attaccttat
    18721 cgctatcttg ctcatttcaa aaatggacaa tgggatcaag gagagcttac agaggatgca
    18781 actttgcata tttcagagtc ttctccaagt cttcactatg gacaacaagc atttgaaggt
    18841 ttgaaagctt atcgtactaa ggatggcagt gttcaactgt tccgtcctga tgaaaatgct
    18901 aaacgtctgc aacgtacatg tgaccgtctc ttgatgccac aagttccgac agacatgttt
    18961 gtagaagctt gtaaagcagt tgtccgtgcg aatgaagaat acgtaccacc atacggaaca
    19021 ggtggaacct tatatcttcg ccctcttttg attggtgtcg gagatattat cggggtaaaa
    19081 ccggcagaag agtacatttt caccatcttt gctatgccag ttggaaatta ctttaaaggt
    19141 ggtttggtcc caaccaactt cttgattcag gatgagtacg accgtgcagc accaaatggt
    19201 acaggtgcgg ctaaggttgg tggaaactat gctgcaagtc tcttaccagg aaaaatggcc
    19261 aagtcacgtc atttctcaga tgttatctat ctggacccat caactcatac aaagattgaa
    19321 gaagtcggat cagctaactt ctttggaatt acagctgata atgaatttgt aacaccatcg
    19381 agtccatcta tcttgccatc tattaccaag tattccttgc tttatttggc agaacatcgc
    19441 ttgggattaa ctcctattga gggtgatgtt ccaattgata atcttgaccg ttttgtagag
    19501 gcaggtgcct gtggtacagc agcggttatt tctccaattg gaggtattca acatggtgat
    19561 gatttccatg tattctatag tgaaacagaa gtaggtcctg tgacgcgtaa attatataat
    19621 gaattgacgg gtattcagtt tggcgatatt gaagcgccag aaggttggag tgtaaaagta
    19681 gattaaaata aaccaaagga gattttttat gaaatagaaa aagtggctct taacagcagg
    19741 agtggtcctg agcacgtcag ctattttagt ggcttgtgga aaaactgata aagaagcaga
    19801 tgcaccgaca acattttctt atgtctatgc agtagatcca gcatcattgg gctacagtat
    19861 agcgactcga acatcgagga cagacgttat tggaaatgtt attgatggtt tgatggaaaa
    19921 tgataaatac ggcaatattg ctccttctca aaaagactat gatttgaaca gtacaggatg
    19981 ggctccaagc tatcaagatc cagcgtctta cttgaatatt atggatccaa aatctggttc
    20041 tgccatgaaa caccttggca ttacgaaagg aaaagataag gatgttgtag ctaaacctgg
    20101 tttggataaa tataagaaat tgttagaaga tgctgtttct gagaccactg acctagagaa
    20161 gagatatgaa aaatatgcca aagctcaagc ttggtcgaca gatagttcat tattgatgcc
    20221 aacagcttca tctggtggtt ttccagttgt aagtaacgta gtaccattct caaaaccata
    20281 ctcacaagtt ggtattaagg gggatccata tatctttaaa ggaatgaaat tgcaaaaaga
    20341 tattgttaca acaaaagaat ataacgaggt ttttaaaaaa tggcaaaaag aaaaattgga
    20401 atccaatagc aaataccaaa aagaactaga aaaacacatt aaataaggaa tggtattgat
    20461 cttgataaaa ttttaaaaat actgtcattt tgaatataaa ggagtttgat atggagtgga
    20521 ttagattaat aggaatagca atcattgttg tgggttttat tttaaaattt gatacaattg
    20581 caacagtagt cttagctggt ttggttacag ctttagtttc aggtgtttct ctcgttgaat
    20641 ttttggagat tttgggaaaa gaatttagca atcagcgagt gctcacgatt tttatggtta
    20701 ccttgcctct tgtggggctg tcagaaacct ttggactcaa gcaacgatca atcgatttga
    20761 ttcgaaagat taaaggtctg acagttggaa acttctatac agtttatttc tttattcgag
    20821 agttagctgg tttcttttca attcgtctag gaggacaccc tcagtttgtc agacctttgg
    20881 ttcagcctat gggagaagca gctgcagagt ctcaattagg tagaaagtta acagaggttg
    20941 aagatgagac aataaaagcg cgtgcggcag cgaatgaaaa ttttggaaat ttctttgctc
    21001 aaaatacgtt tgtaggtgct gggggagtcc tcttgatagg gggaacatta gatcagttag
    21061 gctatgaaag caattatgca gggattgctt ctacatctat tattgttgct gttataacac
    21121 ttattgtagt agggatttac aattatttat ttgataaaaa attgatatca aaaaagacta
    21181 ggggaggaga acaaaaatga cagagttggc aaagcaacta ttagagttga cctatattgt
    21241 gattggttgt caatttctcc atacagccta ttgtagttat aaagataaaa caaacccagt
    21301 tcgacttggg acatctgcat tttggactct attgtctatt acgtttatag gtggttccta
    21361 tatgccaaat atgagtattg gtattattgt aatcctatta tcgctgttaa cattgtttaa
    21421 gcaagtccgt atcggaacct tgccatcctt agatgaaatg aaagccaata ttgaatctaa
    21481 caggttgaaa aataaaattt ttattccagt tatgctgatg gcaatacttg cgttggtctt
    21541 agcgcaaatg attccagaat ttagcaagat ttcgattagc cttgccgcct tgtttgctac
    21601 aatttctgtt cttgtgatta ccaatagtca ccctaagagt ctgttatcag aaaataatcg
    21661 aatgactcag caagtttcaa caagtggtat tgttcctcaa ttattagggg ctttgggggc
    21721 tatttttact gtagcaggtg ttggtgatgt tatctctcat ctgattagcg gtattgttcc
    21781 ttcagatagt cgctttatag gagttttggc ctatgttctt ggaatggttc tattcacaat
    21841 gattatggga aatgcttttg cagcattcac cgttattaca gcaggtgttg gagttccctt
    21901 tgtatttgct ctgggagcta atccaattgt ggctggtgct cttgccatga cagcaggtta
    21961 ttgtgggacc ttattgaccc caatggctgc taattttaac gctctaccag cagcattgat
    22021 ggatatgaaa gatcagaatg gcgttataaa ggctcaagca ggtgttgctc tagtaatgat
    22081 tgttattcac atattcttaa tgtactttct cgcattttag taaaggaaaa taaaatgaaa
    22141 atattggtta caggttttaa tccttttgga ggtgaaaaga ttaatccagc tttggaggct
    22201 gtaaaattat taccatctga gattaatggg gctgaagttc gctgggtaga aattccaacg
    22261 gttttttata agtcgtcaga agttttagag gcagaaatat tacgatatca accagatgct
    22321 gtactttgta ttggacaagc aggcggcagg accggcttaa cacctgaacg agtggctatt
    22381 aatcaagatg atgctcgcat acctgataac gaaggcaatc aaccaattga tacaccgatt
    22441 cgtattgatg gagcatcggc ctattttagt agtttaccta tcaaagcgat ggtacaagct
    22501 atcaaaaaac agggacttcc ggcagttgta tccaatagtg caggaacctt tgtttgcaat
    22561 catttgatgt accaagctct ttatttagtg gataaaaaat tccctaatat gagagcaggt
    22621 ttcatgcata ttccatatat gatggaacaa gtagtaaata agccgaatac tgcaggaatg
    22681 agtctatgtg atattgtaag aggcatagag gtagctattg aagctattgt agactacaaa
    22741 gataaggatt tgcagttagt aggcggtgag actcactgat aacctaaaaa ggatagtcaa
    22801 ttatgcttgt ttactaacta ttaactatgc taaatcaatt gaggttgttt acataaaact
    22861 ctatatcaga gaagcctgat atagagtttt ttcttgctag ttttagaatt ttcttgtaaa
    22921 atagaaaaag tgaagagagg tatgaaatga gcaagaaaga taaaaaaatc gaaattcaag
    22981 tagcggatgc caaagttaat gttggtaaag acagttttga aggttataca ttgactatcg
    23041 gtaaaaaagt tatcggagaa attgccgaat tagacggaca atttgccatt ataaagaatg
    23101 ggaatgtcga tagtttttat aaaaaattgg aaaaagctgt ggaaattttg attgaaaatt
    23161 ataatttagc aaaataagtc ttgttttttt gaaattttca tgatataata gtccatgttg
    23221 attgtaggag agatagcgaa gaggctaaac gcggcggact gtaaatccgc tccttcgggt
    23281 tcgggggttc gaatccctct ctctccattt cattaatggg gtatagccaa gcggtaaggc
    23341 aagggacttt gactccctca tgcgttggtt cgaatccagc taccccagtt cttaggtaat
    23401 aatcaagata aaaagcaaaa tatcttaggg tattttattt ttataattga aagacgtgaa
    23461 tgatatgaac atgtccttgc gggtgcttag gaaaaaaatt ataagtatgt caagtttaag
    23521 aaaaacttga ttgttggagg attttttaga tgaacgaatt tgaagatttg ctaaatagcg
    23581 ttagtcaagt tgagactggt gatgttgtta gtgctgaagt attgacagtt gatgcgactc
    23641 aagctaacgt tgcaatctct ggaactggtg ttgaaggtgt cttgactctt cgcgaattga
    23701 caaacgatcg tgatgcagat atcaatgact ttgttaaagt aggagaagta ttggatgttc
    23761 ttgtacttcg tcaagtagtt ggtaaagata ctgatacagt tacatacctt gtatctaaaa
    23821 aacgccttga agctcgcaaa gcatgggaca aacttgttgg tcgcgaagaa gaagttgtta
    23881 ctgttaaagg aacgcgtgcc gttaaaggtg gactttcagt agaatttgaa ggtgttcgtg
    23941 gatttatccc agcttcaatg ttggatactc gtttcgtacg taatgctgag cgttttgtag
    24001 gtcaagaatt tgatactaaa atcaaagaag ttaacgctaa agaaaaccgc ttcatccttt
    24061 cacgtcgtga agttgttgaa gcagctactg cagcagctcg cgctgaagta ttcggtaaat
    24121 tggctgttgg tgatgttgta actggtaaag ttgctcgtat cacaagcttc ggcgctttcg
    24181 tcgaccttgg tggtgttgac ggattggttc acttgactga attgtcacat gaacgtaacg
    24241 tatcaccaaa atcagttgta actgttggtg aagaaattga agtgaaaatc cttgatctta
    24301 acgaagaaga aggacgtgta tcactttcac ttaaagcaac agtaccagga ccatgggatg
    24361 gcgttgagca aaaattggct aaaggtgatg tagtagaagg aacagttaaa cgtttgactg
    24421 acttcggtgc atttgttgaa gtattgccag gtatcgatgg acttgttcac gtatcacaaa
    24481 tttcacacaa acggattgaa aatccaaaag aagctcttaa agttggtcaa gaagttcaag
    24541 ttaaagttct tgaagttaac gcagatgcag aacgcgtgtc actttctatt aaagctcttg
    24601 aagaacgtcc agcccaagaa gaaggacaaa aagaagaaaa acgtgctgct cgtccacgtc
    24661 gtccaagacg tcaagaaaag cgtgatttcg aacttccaga aacacaaaca ggattttcaa
    24721 tggctgattt gtttggtgat atcgaacttt aatcaaattg aaaattcaca aaatcctttg
    24781 tttactaaac aagggatttt tcta
//
LOCUS       DAVDHC010000029        24560 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVDHC010000029 DAVDHC010000000
VERSION     DAVDHC010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.029"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            193..1086
                     /locus_tag="VUR43_001660"
     CDS             193..1086
                     /locus_tag="VUR43_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5413318.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            1083..2282
                     /locus_tag="VUR43_001661"
     CDS             1083..2282
                     /locus_tag="VUR43_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5413319.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGILNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEV
                     KKNKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(2635..3402)
                     /locus_tag="VUR43_001662"
     CDS             complement(2635..3402)
                     /locus_tag="VUR43_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413320.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(3419..4114)
                     /locus_tag="VUR43_001663"
     CDS             complement(3419..4114)
                     /locus_tag="VUR43_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5413321.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(4119..4484)
                     /locus_tag="VUR43_001664"
     CDS             complement(4119..4484)
                     /locus_tag="VUR43_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET5413322.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            4624..5097
                     /gene="nrdR"
                     /locus_tag="VUR43_001665"
     CDS             4624..5097
                     /gene="nrdR"
                     /locus_tag="VUR43_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET5413323.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            5098..6267
                     /locus_tag="VUR43_001666"
     CDS             5098..6267
                     /locus_tag="VUR43_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET5413324.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSPKETTIIKEAKSKTALQFLAEIKQTRKGTTTQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            6268..7164
                     /gene="dnaI"
                     /locus_tag="VUR43_001667"
     CDS             6268..7164
                     /gene="dnaI"
                     /locus_tag="VUR43_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET5413325.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            7161..7874
                     /locus_tag="VUR43_001668"
     CDS             7161..7874
                     /locus_tag="VUR43_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET5413326.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            7888..9198
                     /gene="der"
                     /locus_tag="VUR43_001669"
     CDS             7888..9198
                     /gene="der"
                     /locus_tag="VUR43_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET5413327.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            9289..9624
                     /locus_tag="VUR43_001670"
     CDS             9289..9624
                     /locus_tag="VUR43_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413328.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            9764..10114
                     /locus_tag="VUR43_001671"
     CDS             9764..10114
                     /locus_tag="VUR43_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413329.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            complement(10336..11187)
                     /locus_tag="VUR43_001672"
     CDS             complement(10336..11187)
                     /locus_tag="VUR43_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5413330.1"
                     /translation="MRWDYGQIFKEIRKSKGLTQQDVCGQVIHRTTLTNIEHGKVIPS
                     FENMVFLLEQIDMSLAEFKYICNEYHPSKRRDIIVESQNPSTFQDTRKMVELTEKCQK
                     YLKTHHDVPIQNIYRHTKIVTELRTKGFKNNHVLKDLYEEIWDYLEPMDTWYISDLKL
                     LGTILFFFPSENLPLLIDRIMKTIEKYKYFRETKAFLSSFLANLSTVYFQHHLFKECE
                     TITLQLLVLAEELKIYDILGFSQVRLGILQHNSDLIDKGITLLRLTKEEALVKILEKE
                     INDFSNL"
     gene            11514..11906
                     /locus_tag="VUR43_001673"
     CDS             11514..11906
                     /locus_tag="VUR43_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413331.1"
                     /translation="MKIKKLLKMVIPVLMISAVGTTFVEANQIGAFSNFVITTSYKRT
                     GYLTKKNEGAEYIMNLNPCRNLHPMTVKHRIVNSNGEARSGESLTTCGTRSTHGNWAT
                     VGYVYAADMARQNWWDLSAAISGSWSPN"
     gene            11928..12719
                     /locus_tag="VUR43_001674"
     CDS             11928..12719
                     /locus_tag="VUR43_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413332.1"
                     /translation="MKIPLLTFARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAILTHFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            12712..13353
                     /locus_tag="VUR43_001675"
     CDS             12712..13353
                     /locus_tag="VUR43_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413333.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            13357..14007
                     /locus_tag="VUR43_001676"
     CDS             13357..14007
                     /locus_tag="VUR43_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET5413334.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            14018..14305
                     /locus_tag="VUR43_001677"
     CDS             14018..14305
                     /locus_tag="VUR43_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413335.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            14451..16964
                     /gene="secA"
                     /locus_tag="VUR43_001678"
     CDS             14451..16964
                     /gene="secA"
                     /locus_tag="VUR43_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET5413336.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            17045..18076
                     /locus_tag="VUR43_001679"
     CDS             17045..18076
                     /locus_tag="VUR43_001679"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET5413337.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            18078..19109
                     /locus_tag="VUR43_001680"
     CDS             18078..19109
                     /locus_tag="VUR43_001680"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET5413338.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            19148..19516
                     /locus_tag="VUR43_001681"
     CDS             19148..19516
                     /locus_tag="VUR43_001681"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET5413339.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            19506..20609
                     /locus_tag="VUR43_001682"
     CDS             19506..20609
                     /locus_tag="VUR43_001682"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET5413340.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            20628..22643
                     /gene="recG"
                     /locus_tag="VUR43_001683"
     CDS             20628..22643
                     /gene="recG"
                     /locus_tag="VUR43_001683"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET5413341.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLNGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            22671..22874
                     /locus_tag="VUR43_001684"
     CDS             22671..22874
                     /locus_tag="VUR43_001684"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413342.1"
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHGFEVVDETDEVS
                     SKHRFEVADRTDEVSNIYTVRRR"
     gene            23200..24180
                     /locus_tag="VUR43_001685"
     CDS             23200..24180
                     /locus_tag="VUR43_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET5413343.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTLEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT         7351 a         4442 c         5471 g         7296 t
ORIGIN      
        1 tatctgcaac ctcaaagctg tactttgagc agcctacggc tagctttcta gtttgctctt
       61 tgcttttcat tgagtataaa agtgctccag gccatatttt acacagcaat agtcttctaa
      121 aaatggacaa aaaacattgt aaaggctatc aaaaaggagt ataatgagtg caagaaattt
      181 cggaggtgaa agatgctaga agtaagaagt ctagagaaaa gttttggatc caagcaagtt
      241 ttgtttggta ttgactttca agcgcgacca ggtcgtattt tgggactagt cggaaaaaat
      301 ggtgctggaa aaacaacgat tttccatagt attttgaaat tcctagaata tcagggagaa
      361 atcggtctgg atggtcagga tattcgtcag gagacctatg ctcggattgg ttatctgcct
      421 gaagaacgca gtctcatgcc taaattgaca gttcttgaac aagttcgcta cttggcgact
      481 ctaaaaggca tggatgccaa agaagtcaaa gaaaaactcc ctcaatggat gaagaggttg
      541 gaagtgaaag gaaagctgac agataaaatc aagagtctgt caaaaggaaa tcagcagaag
      601 attcagctca ttattactct gattcatgaa ccagacctga ttatcttgga tgagcctttt
      661 agtggattgg acccagttaa tacagaattg ctcaaacaag tcatttttca ggaaaaagag
      721 cgcggagcaa ccattatctt ttctgaccat gtcatgacca atgttgagga actttgtgac
      781 gatattctga tgatccgaga tggccgtgtg gtcttgcacg gaccagttca ggatgtccgc
      841 aatcaatacg ggaaaacgcg tctctttgtt tcaagtgaac gaagcaagga agaattggaa
      901 aatcttcctc atgtcaaaca ggtgagcttg accaaacaag gcagttggaa attgattttg
      961 gaggatgaga gcgctggaag ggaactcttc ccaatcttga ctcaaggtca atatatcgca
     1021 acatttgacc aacaagcgcc aactatcgat gaaatcttta aactagaatc aggagtggaa
     1081 gtatgagaaa tatgtgggtt gtaatcaagg aaacctatct tcgacatgtc gagtcatgga
     1141 gtttcttctt tatggtgatt tcgccgttcc tctttttagg aatctctgta ggaattgggc
     1201 atctccaagg ttcttctatg gctaaaaata ataaagtggc agtagtgaca acagtgccat
     1261 ctgtagcaga aggactgaag aatgtaaatg gtgttaactt cgactataaa gatgaagcaa
     1321 gtgccaaaga agcaattaaa gaagaaaaat taaaaggtta tttgaccatt gatcaagaag
     1381 atagtgttct aaaggcagtt tatcatggcg aaacatcgct tgaaaatgga attaaatttg
     1441 aggttacagg tatactcaat gaactgcaaa atcagcttaa tcgttcaact gcttccttgt
     1501 ctcaagagca ggaaaaacgc ttagcgcaga caattcaatt cacagaaaag attgatgaag
     1561 tcaagaaaaa taaaaagttt attcaaacaa ttgcagcagg tgccttagga ttctttcttt
     1621 atatgattct gattacctat gcgggtgtaa cagctcagga agttgccagt gaaaaaggca
     1681 ccaaaattat ggaagtcgtt ttttctagca taagggcaag tcactatttc tatgcgcgga
     1741 tgatggctct gtttctagtg attttaacgc atattgggat ctatgttgta ggtggtctgg
     1801 ctgccgtttt gctctttaaa gatttgccat tcttggctca gtctggtatt ttggttcact
     1861 tgggagatgc tatctcactg aataccttgc tctttatttt gatcagtctt ttcatgtacg
     1921 tagtcttggc agccttccta ggatctatgg tttctcgtcc tgaggactca gggaaagcct
     1981 tgtcgccttt gatgattttg attatgggtg gtttttttgg agtgacagct ctaggtgcag
     2041 ctggtgacaa tctcctcttg aagattggtt cttatattcc ctttatttcg accttcttta
     2101 tgccgtttcg aacgattaat gactatgcgg ggggagcaga agcatggatt tcacttgcta
     2161 ttacagtgat ttttgcggtg gtagcaacag gatttatcgg acgcatgtat gctagtctcg
     2221 ttcttcaaac ggatgattta gggatttgga aaacctttaa acgtgcctta tcttataaat
     2281 agaagagcct tgcgaaagcg aggtttttaa aggtgaaaag ggtggaatca cgaacctaat
     2341 tatgtacaca ttatgtaaac aggttgcttg aaaactcaat tgtatagtga actgaatctg
     2401 gaataggata atattacttc taaaacattc ttataaattg atttgaattc caaaatctca
     2461 tcgttccgtt cttatttcat tttgcgatat agtgaaagga aataagtcag ctcacaaaaa
     2521 acgcataata tcaaggattt ttaacacttg atactatgcg ttttctaatt ttaaagactt
     2581 tttgcctggt ttcttttgtt ctatgagtat gttacatatc taggtaaaaa ttatttaaag
     2641 caaattaacc ttatttctca agatgtagta ggttccgaga taaaagatag ctatgaatat
     2701 gagttcttta acaatggcta tacctgctcc catatagaaa tggtcattga gtcctaccag
     2761 tgaattgaca tagaaattag aactaagatt gaagaaaagt tcaataaatc caatgacgat
     2821 ttggatacca atgtaggctg caacagcgag tgctgtacgg tattcattga aaagctgtcc
     2881 aatggaaata gccaggtaga tgcagaggat tcctgaaatg gtatttagta ggaaggatat
     2941 acctgtaaga aagatctgag ggagatgtgt ttctacaaat gtaatcacat aagaaagagg
     3001 aatccattct ggagctgtta aagccagaat aataacagca cttagagcca atacagcggt
     3061 gctaatcaat gaccagataa aggcaccgat tagtttggct gtgatgatat ggtgttcaga
     3121 aactggcaag gtcaaagtca gatagccttg tcggtcgtag acactacctt tgaagcgttt
     3181 aataatcaag aaaatggttg aaatcgcaag tgtaagcatc aagccaccaa agactgtggc
     3241 tagaaaaagt agcatagtag cctgactttc ttggtaaggt agatttttaa agccttgtgt
     3301 ctgtattccg atgagggcag aaaggactag cacggctgcg tagagggcta aataccactt
     3361 gttaacattt ttaaattcgt agcgaactaa attccaaaac ataaataatc tcctttgctt
     3421 aggccttaaa ttcctgacgg aagagttggt caatggattc acctgactcg tagcgaatat
     3481 catctacatt tccttgacgg acgacttttc cgtcttttag gaagacaatt tcatccaaga
     3541 ttggctcgat atcagaaatc aagtgggtag aaatcaaaac ggtagaagtt ggtgagtagt
     3601 tgttgataat ggtattgagg atataagcac gggctgctgg atccacccca ccaatgggtt
     3661 cgtccaaaac atagagacga gcatcacggc tcataaccaa aatcagttga accttttctt
     3721 tgtttccttt tgatagtttc ttgagacgac tattttcatc aatgcccagg tctgcaagta
     3781 gatgatgagc gcgttcaaga ttgaaatctt tatagaaggt cttgaagtag gttagggctt
     3841 ctttgacctt catttgctca ttgagatagg tcgtatcagg caaataagct acaacggcct
     3901 tggttgctgg gcttgggtcc atgtcgttga tgaggacacg tccttgatct ggttgtaaga
     3961 ggccattaat tagtttaatc agggttgttt ttcctgagcc gtttggccca agaaggccga
     4021 caatttttcc agctggaatg tcaagagaaa cattttcaag ggctggtgtt gctccatatg
     4081 atttggatac attttcaaat gctagtaatg acataggctt aaactccttt aatataatca
     4141 ctgactacgc ctggtagttc ttctttttca tagccaaaat gggtcatgga ggaaacgaag
     4201 tgttccaatt cttcttctga taattgtttg cgtgactgag cgattagctc cttatcctta
     4261 gtcacaaatc gtccagttgt tcgcttgctg tagacaaatc cttctcgttc aaggtctgat
     4321 aaggctcttt ggatggtatt gggattgaca ccagcctcgc tagctagctc cctcacggtt
     4381 ggaagttgtt gattgggttc cagtgtatgg gaaacaatct gaagcttgat tttctccata
     4441 atctgtaaat agatgggttt tttgttgtca aatgtccagg acatcttagt ctcctttctc
     4501 ttattctttt gtcttaatta aataatacaa caaaacaaaa aacttgtcaa gcaaaaagaa
     4561 gaattgtttt gggaatcgct taaaaaatgg tataatgaaa agaaaacgat aaggagggaa
     4621 aggatgcgtt gtccaaaatg tggggctacc aagtcaagtg ttatcgatag tcgccaagca
     4681 gaagaaggga acaccattcg tagaagacga gagtgcgacg agtgccaaca ccgttttaca
     4741 acctacgaac gagtagaaga aagaacctta gtggttgtta aaaaagatgg cacacgggaa
     4801 caattctcca gagataaaat ctttaatggg attatccgct cagcccagaa acgtcctgtg
     4861 tcaagtgatg aaatcaacat ggtagtcaat cgtatcgaac agaaactccg tggtcgaaat
     4921 gaaaatgaaa ttcaaagtga ggacattggt tcactcgtca tggaggagtt ggctgaattg
     4981 gacgagatta cctatgtacg ttttgctagt gtctatcgta gttttaagga tgtcagtgag
     5041 ttagagagct tgctccaaca aatcacccag tcctctaaaa agaaaaagga aagataaatg
     5101 aagccaattg accgtttttc ttatctaaag aataatcggg tgtcgcaaga tacctcatct
     5161 ctggtacagt gctacctccc gattatcggt caggaggcac tgagccttta tctttataca
     5221 atcagttttt gggataatgg tagaaaggaa tatctttttt caagtatcct caatcatctc
     5281 aactttggga tggatagact gataaaatca ttgaaaatct tatctgcttt taatctcttg
     5341 accctctatc aaaaggggga tgtttatcag ctagccctcc atgctcctct atctagtcaa
     5401 gacttcttgg agcatcctgt ttatcgcaga ctcttagaga aaaagattgg cgactctgct
     5461 gtggaggatt tgaaagttga aagtgctgat ggtgaagaaa tacctgtctc actcaatcaa
     5521 gtctttccag aattggcaga actaggcagt caagaagacc ttggtctcaa gaagaaagtg
     5581 gccaatgatt ttgacttgga tcattttcgt cagctgatgg ctcgagatgg acttcgtttt
     5641 gcggatgagc agtctgatgt cttgaacttg tttgctattg ctgaggagaa gaagtggact
     5701 tggtttgaga cctatcaatt ggccaagtca acagctgttt cccaggttat ttcaaccaaa
     5761 cgcatgcggg aaaaaattgc tcaaaaacca gtttcctcgg actttagtcc taaggaaaca
     5821 accattatca aggaagctaa aagtaaaact gccctgcagt tcttggcaga aatcaagcaa
     5881 acacgcaagg gaaccactac ccaaacagaa agagaactct tgcaacagat ggctggcttg
     5941 ggcttgctgg acgaagtcat caatatcatt cttttattga cctttaataa ggtcgattcg
     6001 gcaaatatca atgagaaata tgccatgaag gtagccaatg actatgccta tcaaaagatt
     6061 cattcggcag aagaggcagt cttgcgcatc cgtgagcgag gacagaaagc aaaaacacaa
     6121 aaacagaatc agactgcccc agtaaaaacc aatgttccta aatggagtaa tcctgaatat
     6181 aagaatgaaa ccagcgagga aactcgtctg gaactagaac gtaagaagca agaactatta
     6241 gctcgattag aaaaaggagg agattagatg gaaagtgtcg gagacgtact caaacgtcaa
     6301 cccagccgtt tttattatca agatttggtc cagaaaatca tgaaggaccc tgatgttgcg
     6361 gcttttatcc agcaagaatc cttgactcca gaggaattaa atcgcagtat ctccaagttt
     6421 aatcagtaca tcaccgagcg tgacaagttt ctccgtgggg atacggatta tattgccaaa
     6481 ggctacaagc cgattttggt taagaatcat ggctatgcag atgtttcata tgaagaaact
     6541 cctgagctaa tcgcggctga aaaagaagcg gctattaaga accgtctcaa gttaatcaat
     6601 ctaccagcca gtctcaagaa agctagtttg gctcaagttg acttggatga tttggggcgc
     6661 ttaccagttt ttgaaaagct actagccttc gtggagcaat atccagctat tcgaaaaggt
     6721 ctttacttgt atggagactt tggtgtgggt aaaagtttca tggtggctgc cctagctcat
     6781 gatttatcag aaaaacgtgg tgtatcatcc actctcctcc actatcctag ctttgtcatt
     6841 gatgtcaaaa atgctattgg tgatggcaat gttaagacct tagtggatga gattaagctt
     6901 tctgaagtcc tgattttaga tgatattggt gccgagcaat ccaccgcttg ggtgcgtgat
     6961 gaaatcctac aggtcattct ccaatatcgg atgcaggaaa atttaccgac ctttttcacc
     7021 tctaacttca actttgaaga tttggagaag catttcgcta aagggaaaaa tggaaatgac
     7081 gaaacctggg aagccagacg ggtcatggaa cgcatccgtt atttggctga ggagactcgt
     7141 ttagaaggag taaaccgtcg atgacagaaa ccattaaatt gatgaaggct catacttcag
     7201 tgcgcaggtt taaagagcaa gaaattcccc aagtagactt aaatgagatt ttgacagcag
     7261 cccagatggc atcatcttgg aagaatttcc aatcctactc tgtgattgtg gtacgaagtc
     7321 aagagaagaa agatgccttg tatgaattgg tacctcaaga agccattcgc cagtctgctg
     7381 ttttccttct ctttgtcgga gatttgaacc gagcagaaaa gggagcccga cttcataccg
     7441 acaccttcca accccaaggt gtggaaggtc tcttgattag ttcggtcgat gcagctcttg
     7501 ctggacaaaa cgccttgttg gcagctgaaa gcttgggcta tggtggtgtg attatcggtt
     7561 tggttcgata caagtctgaa gaagtggcag agctctttaa cctgcctgac tacacctatt
     7621 ctgtctttgg gatggcactg ggtgtgccaa atcaacatca tgatatgaaa ccgagactgc
     7681 cactagagaa tgttgtcttt gaggaagaat accaagaaca gtcaactgag gcaatccaag
     7741 cttatgaccg tgttcaggct gactatgctg gggcgcgtgc gaccacaagc tggagtcagc
     7801 gcctagcaga acagtttggt caagctgaac caagctcaac tagaaaaaat cttgaacaga
     7861 agaaattatt gtagaaagtg agaaattatg gccctaccaa ctattgccat tgtaggacgt
     7921 cccaatgttg ggaaatcaac cctatttaat cggatcgctg gtgagcgaat ctccattgta
     7981 gaagatgtcg aaggagtgac acgtgaccgt atttatgcaa cgggtgagtg gctcaatcgt
     8041 tcttttagca tgattgatac aggaggaatt gatgatgtcg atgctccttt catggaacaa
     8101 atcaagcacc aggcagaaat tgccatggaa gaagcagatg ttatcgtctt tgtcgtgtcc
     8161 ggtaaggaag gaattaccga tgcagacgaa tacgtagccc gtaagcttta taagacccac
     8221 aaaccagtta tcctcgcagt caacaaggtg gacaaccctg agatgagaaa tgatatctat
     8281 gatttctatg ctctcggttt gggtgaacca ctgcctatct catctgtcca tggaatcggt
     8341 acaggggatg tactagatgc tatcgtagaa aatcttccaa atgaatatga ggaagaaaat
     8401 ccagatgtca ttaagtttag cctgattggt cgtcctaacg ttggaaaatc aagcttgatc
     8461 aatgctatct tgggcgaaga ccgtgttatt gccagtcctg ttgctggaac aactcgtgac
     8521 gctattgata cccactttac agatacagat ggtcaagagt ttaccatgat tgatacggct
     8581 ggtatgcgta agtctggtaa ggtttatgaa aatactgaga agtactctgt catgcgtgcc
     8641 atgcgtgcta ttgaccgttc agatgtggtc ttaatggtca tcaatgcgga agaggggatt
     8701 cgtgaatacg acaagcgtat cgctggattt gctcatgaag ctggtaaagg gatgattatc
     8761 gtggtcaaca aatgggatac gcttgaaaaa gataaccaca ctatgaaaaa ctgggaagaa
     8821 gatatccgtg agcagttcca atacctgcct tacgcaccga ttatctttgt atcagcttta
     8881 accaagcaac gtctccacaa acttcctggg atgattaagc aaatcagcga aagtcaaaat
     8941 acacgtattc catcagctgt cttgaacgat gtcatcatgg atgccattgc catcaaccca
     9001 acaccgacag acaaaggaaa acgtctcaag attttctatg cgacccaagt ggcaaccaaa
     9061 ccaccaacct ttgttatctt tgtcaacgaa gaagaactca tgcacttttc ttacctacgt
     9121 ttcttggaaa atcaaatccg caaggccttt gtttttgagg gaacaccgat tcatctcatc
     9181 gcaagaaaac gcaaataaaa aagtagaatc tggaatgaca gttccggatt tttttgatat
     9241 aataaaataa tagaaaacgc tatcaaaaga aggaggggga tgtcggtgat ggaacatttg
     9301 tttaaattct tacttttagc accgtacttt tattttgata actggattga aaaggccaac
     9361 agaaatagta agttttttcc aattttttat tatttttact ggatttacat ccccttctat
     9421 tctcttttta gccttgcttg gacagttgtt tcagttctgt ttttcaatac cgtcttgaga
     9481 aatgtgacag atatcaagtt atggggcatt tggtttcttt ttattctgct agctattggt
     9541 atgaattggt taacttattc ctgtttcaaa gaaatgtttc gcttgagaca ggaactaggg
     9601 aagtctaagg gtggaaggca ttgatttata tcggtttcta tttgtaggag gtggcttatg
     9661 gtacctctaa aatcatttat tacacgctat tccaaggttt atattggtaa taacatttaa
     9721 tagaacgaaa ctaaagaaaa caatttaaaa aaggaggctt gtgatggaac acttgtttaa
     9781 aatgataatc ttattaccct gtttttactt tttcagctgg attgacaagg ataatagaga
     9841 aagtaaattt ttcccaattt tttactattt ttactggatt tacatcaccc tctatgctct
     9901 ttttagcctt gcttggacag ttttttcagt tctgtttttc aatatcgtct tgagaaattt
     9961 gacagatatc aagttatggg gtatttggct attattacta cttatcgctt ttgctagtga
    10021 ctggttagac tatatctgtt tcaaaaaaat gcttgacttg agacgggaac tagggaagtc
    10081 taaaggtgtg cataaaggaa ggtgtaggaa ctaaaaaatg actgtatcta tgatttgttt
    10141 atggagctat agatacagtc atttttattt tgattatgaa acttgagaga aatattcatc
    10201 ttgtatagtg gattgaatat ggaataatac aatacaactt ataaaacatt ggtataaaat
    10261 gctttagatc ccctaattga ttcgttcaca ttctattaca atctactata ataaaatgat
    10321 gagagttatt acaaattata ggtttgaaaa atcattaatt tctttttcga gtattttaac
    10381 taatgcctct tctttggtta gtcgtaataa agttattcct ttatcaatca aatcggagtt
    10441 atgttgtagt attcccaagc gtacttgaga gaatccaaga atatcgtata tttttaattc
    10501 ttctgctaat accaaaagtt gtagggtgat tgtttcacat tctttgaata aatgatgttg
    10561 aaaatataca gtggagagat tggctaaaaa agatgataaa aatgcttttg tttctcggaa
    10621 gtatttatat ttctcgatgg ttttcataat tctatcaata agaaggggaa gattttcaga
    10681 aggaaagaaa aagagaatgg ttccaagcaa tttcaaatca ctaatgtacc atgtatccat
    10741 aggttcaaga tagtcccaaa tttcttcata caaatctttc aagacgtggt tgtttttgaa
    10801 tcctttagtt cgtaactctg tgacaatttt tgtatgacga tagatatttt gaataggaac
    10861 atcgtgatgt gtcttaagat atttttgaca tttctcagtg agttcaacca tttttctagt
    10921 atcttgaaaa gtagacggat tttggctctc tacaataata tctcgccttt tactaggatg
    10981 gtattcgttg catatatact tgaattctgc caagctcata tcaatttgtt caagaagaaa
    11041 taccatgttt tcaaaactgg gaataacttt accgtgttca atatttgtta gagttgttcg
    11101 atgtatgact tgtccacata catcttgttg ggtcaatcct tttgactttc gaatttcttt
    11161 aaaaatttgt ccataatccc atctcatatt gttcctccta ggtaaatgtg aatattttct
    11221 acatttataa aaaacgtaga aaaaggtggt attattatat caaaaaggag ggaaaaagtc
    11281 atgggcttta aaaaatattt gaagaattta ccgaaaaact ctggattttt gatttggagt
    11341 tggattcaac ttatctggtt tgaaacatgg ttttggggat aaagaaatta gagtctatac
    11401 ataataagta aaggaggaat ttgtatgata taccatcgtt tagaataagt ctatatttaa
    11461 aatagaagtt ataaggaatc ttcttgaata aaaaatgaaa ggaaacagaa aaaatgaaaa
    11521 ttaagaaatt attgaaaatg gttattcctg ttttaatgat aagtgctgtt ggaactactt
    11581 tcgtagaagc aaatcagata ggtgctttta gtaattttgt tattactacc agttataaga
    11641 gaacaggtta tttgactaaa aaaaatgaag gtgcggaata tatcatgaac ttaaatcctt
    11701 gtagaaattt acatcccatg actgttaagc atcgtatagt aaattctaat ggagaagctc
    11761 gtagtggaga atcgttaaca acctgtggta ctcgttcaac tcatggtaat tgggcaacgg
    11821 ttggctatgt ttatgcagca gatatggcaa gacaaaattg gtgggattta tcagctgcca
    11881 tttcaggtag ttggtcacca aattaattcg taaagtaggt ataatttatg aagattcctc
    11941 tcttaacttt tgcaaggcat aaatttgttt atgtcttgct tactttgctt tttcttgctt
    12001 tggtttatcg tgatgttttg atgacttatt tcttttttga tattcatgcg cccgatctag
    12061 ctaaattcga tggacaagca attaaaaatg acttattaaa atcagcatta gattttcgta
    12121 ttctccagtt caatctaggt ttttatcaat catttattat tccaatcatc attgttttgc
    12181 taggttttca atatattgag ctgaaaaata aagttttacg attgagtatt ggaagagaag
    12241 tgagttatca agggttaaaa agaaagttga ctttgcaagt tgcaagtatc ccttgtttga
    12301 tatatttagt gactgtgctg ataattgcaa ttttaactca tttctttggg actttttctc
    12361 ctcttggatg gaattctcta ttttctgatg ggagtagttt acaaaggctc ctagatggag
    12421 agataacaag ctatttgttc tttacttgtg tcctactaat cggtattttc atcaatgcaa
    12481 tctatttttt acaaatagtt gattatgtgg ggaatgtgac tcgttcggca atcacctatt
    12541 tgatgtttct ttggcttggt tctatgctgc tctatagtgc cttgccttac tatatggttc
    12601 ctatgacgag tttgatgcaa gctagctatg gggatgtaag tttgatgaaa ctctttactc
    12661 cttatatcct ttatattgtc ccttacatgg tgcttgaaaa atatgaagat aatgtttaag
    12721 aattttaaca atattttgct aaagagaaag attgttttac tacttcgtat agttctgatg
    12781 atgattttga taaaccatct attgtcaaca gcggttcaaa agcaggatgc tgttatcttt
    12841 ttcaagagag aattgatttc aattttttcc tataatgact attctgaagc gaatttagaa
    12901 atccccaaac tcttgttaaa cctttcgctt ttcatggtag gatggctctc tgtcatttta
    12961 cttgaaagtg atttggcaga ccattaccat cacttgattc gctatcaatc aagctccttt
    13021 ttcgattata caaggaaacg attggttgtc atttctaaat tttttactca agatttgttt
    13081 gtctggtttc ttggtttact tccgctagga attcatttca aaacagtcgc acttttcttt
    13141 ttacttgctc agttaatgat gttgtactta ctactgtctt atctgatagc actgattagt
    13201 gcgggcgctg gtttttcttt ttttctctat tttttggcat ttgtgggaca agaatggatg
    13261 atggatcata ttgtaacagt gtatttagta ctcttaagct tattagttat gttgattctt
    13321 agtcgcttgg aagagaaatt taagaaagga taaacgatga gacttgaaat tataaatgga
    13381 cagaaaattt atgggaaaag acctatttta aatcagttga atttggtgtt tcaatcagga
    13441 aaaatttatg gacttaaagg tgataatgga tctggcaaga cggttctttt aaagatactt
    13501 gctggttata ttaagcttga caaaggaaaa gttcttcaag atggtaaagt ttacggggta
    13561 aaaaatcatt atattcagga tgcaggaatt ttaattgaaa aagtcgagtt tttatctcat
    13621 ttatccctga gagaaaattt ggaactgtta aggtattttt catctaaagt tacggaaaaa
    13681 agaattgcct attggattca atactatgat ttacaggaat ttgaagatgt tgaataccgt
    13741 catttatcct tgggaacaaa gcaaaaaatg gccttgattc aagcctttat ttcctctcct
    13801 tctatactct ttctcgatga acctatgaat gctttggatg agaaaagtgt gaggttaacc
    13861 aaacaggtca ttttatctta cctgaaaaaa gaaaatggtc tggttatcct gacgtcgcac
    13921 atatcggaag atatttcaga cctttgtaca gatgtattag ttgtcgaaaa tggacatata
    13981 caatatgtaa aggatataca atcctaggag atggcttatg gcacatctaa aatcatttat
    14041 tacacgctat tccaaggttt atattggttt agttctgctg atctggctgt ctttcttctt
    14101 tatcccttgg gatagagcga ttctgggggt aaggattgac atcttcatca tacagaaagt
    14161 cttgctagtt tttggaattc tgtccatttt gatggccttg ctgtccaaga aagtcagtct
    14221 ctttgttttt ggactgattt gctgtctttc tctttggatt aacttattta tcacatttgc
    14281 cattttgccg atttttggca attaaacagt cataaaagtc ggagaggtta gcttgaaaac
    14341 taacctcttt ttccttttca aaatggggat tcttccttga aaataatcag taattgtgct
    14401 aaaattaaag gaacattcta aaatattcgg aatttaaagt aaggaaaaac atggctaata
    14461 ttttaaaaac aattatcgaa aatgataaag gagaaatccg tcgtctggaa aagatggctg
    14521 acaaggtttt caaatacgaa gaccaaatgg ctgctttgac tgacgaccaa ctaaaagcaa
    14581 aaacagttga atttaaggaa cgttatcaaa atggagaatc actggattca ttgctttacg
    14641 aagcatttgc ggttgtccgt gaaggtgcca aacgtgtcct aggtctcttc ccttataagg
    14701 ttcaggtcat gggggggatt gttcttcacc atggtgacgt gccagagatg cgtacagggg
    14761 aagggaaaac cttgactgcg accatgccgg tatacctcaa tgccctttca ggtaaagggg
    14821 ttcacgtagt tacggttaat gaatacctgt cagaacgtga cgcgactgag atgggtgaat
    14881 tgtactcttg gcttggtttg tcagtaggga ttaacttggc taccaaatct ccaatggaga
    14941 aaaaagaagc ctatgagtgt gatattactt actcaactaa ctcagaaatc ggatttgact
    15001 accttcgtga caacatggtc gttcgcgctg aaaacatggt acaacgtccg cttaactatg
    15061 ccttggtcga tgaggttgac tctatcttga ttgacgaggc tcgtacacct ttgattgtat
    15121 caggtgccaa tgcggttgaa accagtcagt tgtatcacat ggcagaccac tatgtaaaat
    15181 ctttgaacaa agatgactac atcatcgatg tgcagtctaa gactattggt ttgtctgatt
    15241 cagggattga cagggctgaa agctacttca aacttgaaaa cctctatgac atcgaaaacg
    15301 tggctttgac ccactttatc gataacgccc ttcgtgccaa ctacatcatg cttctcgata
    15361 ttgactatgt ggtgagcgaa gagcaagaaa tcttgattgt cgaccaattt acaggtcgta
    15421 ccatggaagg tcgtcgttat tctgatggat tgcaccaagc tattgaagcc aaagaaggtg
    15481 tgccaatcca ggatgaaacc aagacatctg cctcaatcac gtaccaaaac cttttccgta
    15541 tgtacaagaa attgtctggt atgacgggta caggtaagac tgaggaagaa gaattccgtg
    15601 aaatctacaa cattcgtgtt attccaatcc caacaaaccg tcctgttcaa cgtattgacc
    15661 actcagacct tctttatgca agtatagaat ctaagtttaa agcggttgtc gaagacgtta
    15721 aggctcgtta ccaaaagggt caacctgtct tggttggtac agtagcggtt gaaactagtg
    15781 actacatttc taagaaattg gttgcagctg gtgttcctca cgaagtcttg aatgccaaaa
    15841 accactatag agaagcccaa atcatcatga atgctggtca acgtggtgcc gttaccatcg
    15901 caaccaacat ggcgggtcgt ggtaccgaca tcaagcttgg tgaaggtgtt cgtgaacttg
    15961 gaggactttg tgttattggt acagaacgtc atgaaagtcg tcgtatcgat aaccagcttc
    16021 gtggacgttc aggtcgtcaa ggagatccag gtgagtcaca attctaccta tctcttgaag
    16081 atgatttgat gaaacgtttt ggttctgaac gcttgaaggg aatctttgaa cgcttgaaca
    16141 tgtctgaaga ggcgattgag tctcgcatgt tgacgcgtca ggttgaagca gctcagaaac
    16201 gtgtcgaagg aaataactac gatacccgta aacaagtcct tcaatacgat gatgtcatgc
    16261 gtgaacaacg tgagattatc tatgctcaac gttacgatgt catcactgca gatcgtgact
    16321 tggcacctga aattcagtct atgattaagc gcacgattga acgtgtcgtt gatggtcatg
    16381 cgcgtgccaa acaagatgaa aaactagagg caattttgaa ctttgctaag tacaacttgc
    16441 ttcctgaaga ttctattacg atggaagact tgtcaggctt gtctgataag gccatcaagg
    16501 aagagctttt ccaacgtgcc ttgaaggttt acgatagtca ggtttcaaaa ctacgcgatg
    16561 aagaagcagt taaagaattc caaaaagttt tgattctacg agtggtggat aacaagtgga
    16621 cagatcatat cgatgccctt gatcaattgc gtaacgcggt tggacttcgt ggctatgctc
    16681 agaacaaccc tgttgttgag tatcaggcag aaggtttccg tatgtttaat gatatgattg
    16741 gttcgattga gtttgatgtg acacgcttga tgatgaaagc acaaattcat gaacaagaaa
    16801 gaccacaggc agaacgtcat atcagtacaa cagcgactcg caatatcgct gctcaccaag
    16861 caagtatgcc agaagatttg gatttgagcc agattggacg caatgaactt tgcccatgtg
    16921 gttctggtaa gaaatttaaa aactgtcacg gtaaaagaca ataaaatgag atagtttaga
    16981 ggcggatatc ttgtgaaaag taaattttta ctgggtatcc gtttgcttta taaggagatg
    17041 agttatggta tttacagcaa aaagctctaa aataaatata gaagaagttc gtgccttgtc
    17101 aaaattagaa ggtcaggctt tggagaggaa atcacagaga gatcaagagc tagaagccat
    17161 tatacgtgga gaagaccagc gaattctctt ggtaatcggg ccatgctcat ctgataacga
    17221 agaagctgtc cttgaatacg ctaagcgttt ggcagtccta caagaagaag tggcagatcg
    17281 tatctttatg gttatgcgtg tttatactgc caaaccccgt accaacggag atggctataa
    17341 aggcttgatt caccagccta acgcgacaga agcgcctagt cttatcaatg gaatcaaagc
    17401 cgttcgccat cttcactatc gtgtcatcac agaaacaggg atgacaactg ctgatgaaat
    17461 gctttatcct gaaaaccttc cgcttgtaga tgatttgatt tcttacatgg cagttggtgc
    17521 ccgttcagtt gaagaccagc aacaccgctt tgtggcaagt ggggcaggat tttctactgg
    17581 ttttaaaaat ccaacctctg gaaatctcaa tgtcatgttt aatgggattt atgctgctca
    17641 aaacaaacaa agtttccttt tcttaggaaa agaagtagaa acaactggga acccgctttc
    17701 acacgctatt cttcgtggtg ctcttaatga gtatggaaaa aatattccca actactatta
    17761 tgacaattta attgatacca ttgcccagta tgagaaaatg ggcttggaaa atccttttat
    17821 catcattgat accaatcatg acaattctgg taagcagtat attgaacaga tccgaattgt
    17881 ccgccagacc ttgattaacc gtgcttggaa tgaaaaaatt aagcagttcg ttcgtggttt
    17941 tatgattgag tcttatctgg aagatggtcg acaaaatgag ccagaagtat ttggtaagtc
    18001 tatcacagac ccttgcctgg gttgggataa cacagaagct cttgtcagag aaatttacaa
    18061 aacgttagga gaataagatg gcatttattg aaaaaggtca agaaatcgat atggaagtca
    18121 tcaaggctga aacccaattg tctgcagaag ccttgagact caaggaaagc cgtgacaggg
    18181 aattggcaga tattatttca ggggaagatg accgtattct cttggtgatt ggtccttgct
    18241 cttctgataa tgaagaggcg gtcttggaat atgctcgccg tttatccgcc ttgcaaaaga
    18301 aggtagcgga caagattttc atggtcatgc gcgtgtatac tgctaagcct cgtaccaatg
    18361 gagacggcta taaaggattg gttcaccagc cagatacttc taaggctcca agcctgatta
    18421 acggcttgca ggctgtgcgc cagttgcact accgcgtgat tacagagact ggtttgacaa
    18481 cggcagatga gatgctttat ccgtcaaatc tgatcttggt ggatgacttg gtcagctacc
    18541 atgccgttgg agctcgttct gtggaagacc aagagcaccg ctttgtggct tctgggattg
    18601 atgcaccagt agggatgaaa aatccaacct caggaaattt gggtgttatg tttaacgcca
    18661 tctatgctgc tcaaaacaag caaaccttcc tttatcatgg gcaggaagtt gagacatcag
    18721 gtaatccttt ggcccatgtt atcctccgtg gagcagtcaa cgagtatggc aattatatgc
    18781 cgaattacta ctatgaaaac ctactccaag ccattgaacg ctatgaaacc atgggacttg
    18841 aaaatccttt tatcctcatt gacaccaacc atgataactc aggcaagcaa tatatggagc
    18901 agattcgaat tgttcgccag accttgcaga atcgtgattg gaatgagaaa attaaaaaga
    18961 cggttcgagg atttatgatt gaatcttacc tagcagatgg tcgtcaaaac caaccagaga
    19021 tctttggttg ctctattact gacccttgcc taggttggga aaatacagag gccttggtag
    19081 aagagattta tgttaccttg acaaaataag tgaaaaggat ggagttgggg aatctcaact
    19141 ccttttgatg agaatgatag ttggacacgg aattgacatc gaagaattgg cttcgataga
    19201 aagcgcagtt acacgacatg aaggatttgc taagcgtgta ctgaccgctc aggaaatgga
    19261 gcgcttcacc agtctcaaag gacgcaggca aatagaatat ttagctggtc gctggtcggc
    19321 taaggaggcc ttttccaagg ctatgggaac gggcattagc aagctcggtt ttcaggattt
    19381 ggaagtcttg aacaatgaac gtggggcgcc ttattttagt caggcaccat tttcaggaaa
    19441 gatttggctg tctatcagcc acaccgatca gtttgtgaca gccagtgtca ttttggagga
    19501 aaatcatgaa agctagtcca catagaccaa ccaaggctct gattcatctg ggagctattc
    19561 gacaaaatat tcagcaaatg ggggctcata tccctcaagg aacgctcaag ttggctgtgg
    19621 tcaaggccaa tgcttatggt catggagctg ttgccgttgc caaggcaatt caagatgatg
    19681 ttgatggctt ttgcgtttcc aatatcgatg aagccattga actcagacaa gctggactca
    19741 gcaagccaat cctcatttta ggagtttctg aaatcgaagc tgttgctcta gctaaagaat
    19801 atgacttcac cttgacagtg gctggactgg agtggattca agcactctta gataaggaag
    19861 tggacctaac tggattgaca gtccacctca agattgattc agggatggga cggattggtt
    19921 ttagagaggc cagtgaggtt gagcaggctc aagatttgct ccaacaacac ggtgttcgtg
    19981 ttgaaggaat ctttacccac tttgctactg ctgatgagga atcagatgac tattttaatg
    20041 cccagttaga acggtttaaa actattttag ctagtatgaa ggaagttcca gagctggttc
    20101 atgctagcaa ttctgcaacg actctttggc atgtagagac tattttcaat gcggttcgta
    20161 tgggagatgc catgtatggc ctcaatccaa gtggagcggt cttggatttg ccttatgatt
    20221 tgataccggc cttgaccttg gagtctgctc tggttcatgt caagacagtt ccagctggag
    20281 cttgcatggg ctatggagca acttatcaag cggatagcga gcaagtcatc gcgaccgtac
    20341 caatcgggta tgcagatgga tggacaagag acatgcaaaa tttctctgtc ttggtagatg
    20401 gccaagcttg cccaattgtc ggcagggttt cgatggacca aatcactatt cgattgccta
    20461 agccttaccc actcggaacc aaggtaacct tgattggctc caatggggat aaggaaatca
    20521 ctgcaactca ggtagcgacc taccgcgtaa ccattaacta tgaggtggtt tgcctcctca
    20581 gcgaccgtat tccgagagaa tattattaga aaagaaagga gtggagcatg aatctacatc
    20641 aacccttgca tgtcttgcct ggtgtgggac caaagtcagc agaaaaatat gccaaactag
    20701 gaattgaaaa cttgcaagat ctcttgctct actttccttt ccgttatgaa gacttcaaaa
    20761 ccaagcaggt gctggagctg gaagacggtg agaaggcagt tctttctggt caggtagtga
    20821 ctcctgctag tgtccagtat tatggtttca agcgcaatcg cctgcgtttt agtctcaagc
    20881 agggagaggt cgtttttgcg gtgaatttct ttaaccagcc ctatctggct gataaaatag
    20941 agttgggagc aacccttgct gtctttggaa aatgggaccg cgctaaggct agtctgaatg
    21001 ggatgaaggt tctggctcag gtagaagatg acctccagcc tgtttatcgt ctggctcagg
    21061 gaatcagtca ggccagtctg gttaaggtca tcaagacggc ttttgatcag ggactggacc
    21121 tcttgataga agaaaatctg ccccagtctt tactagacaa atacaaactc atgtcccgtt
    21181 gtcaggcagt ccgagctatg cattttccaa aggatttggc agaatacaag caggctcttc
    21241 gccgtataaa gtttgaggaa ctcttttatt tccaaatgca gctgcagatg ctcaagtctg
    21301 aaaatagagt tcagggaagt ggtctggttc tggattggtc tcaggaaaaa gtgacagcag
    21361 ttaaagcaag tcttcctttt gccctgaccc aagctcagga aaagagtttg caggaaattt
    21421 taactgatat gaagtccgac caccacatga atcgtctcct acaaggggat gtggggagtg
    21481 gaaaaacggt agtcgctggc ttggccatgt ttgcggcagt gacagcaggt tatcaggctg
    21541 ccctaatggt accaacagaa atcctcgcag agcaacactt tgagagttta cagaaccttt
    21601 ttcccaattt gaaactggct ctcttgacag gttccttgaa agctgcagaa aagagagaag
    21661 tcttggagac cattgccaag ggtgaggctg atttgattat aggaactcac gctctgatac
    21721 aagatggggt ggagtatgct cgtcttggtt tgattattat cgatgagcag caccgttttg
    21781 gtgtagggca aaggcgtatt ttacgggaaa aaggtgacaa tccagatgtc ctcatgatga
    21841 cggcgactcc cattccacgg acgcttgcca tcacagcctt tggagatatg gatgtttcca
    21901 ttatcgacca gatgccagca ggtcggaagc ctattgtgac gcgctggatc aaacatgagc
    21961 aactacctca ggtcttgact tggttagagg gggaaattca aaaaggttcc caagcctatg
    22021 tcatctctcc tttgattgaa gaatcagaag ctctagattt gaaaaatgcc attgccttat
    22081 cagaggagtt gacgactcat tttgcaggca aggcagaggt ggctcttcta catggtagga
    22141 tgaagagtga cgaaaaagac cagatcatgc aggatttcaa ggagagaaag acggatattc
    22201 tggtttcgac gacggttatt gaggttgggg tcaacgttcc caatgcgact gtcatgatta
    22261 tcatggatgc cgatcgcttc ggtctcagtc aacttcacca gcttagaggt cgtgtcggtc
    22321 ggggggacaa gcagtcctac gctgttctcg ttgccaatcc caagacggat tctgggaaag
    22381 accgcatgcg catcatgaca gaaacgacca atggatttgt ccttgcggag gaagatttga
    22441 aaatgcgtgg ttctggtgag atttttggaa ccagacagtc aggacttcca gagttccaag
    22501 tggctgatat tatcgaagat tttccgattt tagaagaagc aagaaaggtt gctagctaca
    22561 ttagttctat agaagcttgg caagaagatc cagagtggcg catgattgcc cttcatctgg
    22621 aaaagaaaga acatctggat taagctttct ctaaggaaaa cttatactca atgaaaatca
    22681 aagagcaaac taggaagcta accgcaggtt gctcaaaaca ctgttttgag gttgtggatg
    22741 aaactgacga agtcagctca aaacatggtt ttgaggttgt agatgaaact gacgaagtca
    22801 gctcaaaaca ccgttttgag gtggcagata gaactgacga agtcagtaac atatatacgg
    22861 taaggcgacg ctgacgtggt ttgaagagat tttcgaagag tattaagcta gtttttaggt
    22921 ttggctctta tactaaagtc atcaaaaaga aacgaggact ctcatatgac agtaacgatt
    22981 aaagtaaatt accaaaccac tttccaaaag aaggaagcaa aaaactagta taaacagaag
    23041 agagagcgaa atgctctttt tcgtttctaa aactactttc agcccatcat cctaaaagta
    23101 aagaatctaa attcactttc tatttatcct tctttcttgc attgattaca tagatatgct
    23161 acagttgtgg taacgattac aaaataaaag gagcatgcta tgaaaaatcc agctttgcta
    23221 gaagaaatta agacctatag aggaagggat gaggttccgg aagactttga tgctttctgg
    23281 gatggggaag tgaaaaatgt ttccacgctt ccatcctacc acttggagga aagagatttc
    23341 cacattcctc aagtcaagtg ctatgagtta acattggaag gaagcaagga aggaaaggtc
    23401 tatgcacgca ttgttcttcc aaagagtgag gagaaggttc cactaatctt ccattttcat
    23461 ggttatatgg gacgtggctg ggactgggcc gacatgctgg gcttcaccgt agctggttac
    23521 ggtgttgttt ccatggatgt gcggggccag tcaggttact cacaagacgg cttgcgttct
    23581 cctttaggaa atacggttaa ggggcatatt atccgtggtg ctatggaagg tcgggaccac
    23641 ctcttttata aggatgttta tctggatatt taccagttgg tcgaaattgt tgctagtctg
    23701 tctcaggttg atgagaagcg tctttctagc tatggtgcct cacaaggagg ggctctagct
    23761 ctagttgcag cagcgctcaa tcctcgaatt cagaaaacag ttgccattta tcccttcttg
    23821 tcagacttca gacgggtgat tgagattggt aatactagcg aggcttacga cgaacttttc
    23881 cgttatttca agtttcacga ccccttccat gaaacagagg aggaaatcat ggcgaccctt
    23941 gcctatatcg atgtcaaaaa tcttgcccat cgtatccaag gtgaggttaa gatgattacg
    24001 ggcttggacg acgatgtttg ctatcccatt acccagtttg cgatttataa tcgtctgacc
    24061 tgcgataaaa cctatcgtat catgcctgag tatgctcacg aagccatgaa tgtatttgtt
    24121 aatgaccaag tctacaactg gctctgtgga agtgagattc cttttaaata tctaaaataa
    24181 ggagtcgact ctaagcacaa aatcttaaaa attacaaaca cgcatagtat caggggatta
    24241 agagaacttg atactatgcg ttttatcatg gaaatatagt aaaatgaaac aagaacagga
    24301 caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag atgtgtacta
    24361 ttctagtttc aatctattgt atttatagaa ttttttgttg ctagatttgt caaattgctt
    24421 aaaataattt ttttcagaaa gcaaaagccg atacctatcg agtagggtag ttcttgctat
    24481 cgttaggctt gtctgtaggt gttaatactt ttcaaaaatc tcttcaaacc acgtcagctt
    24541 cgccttgccg tatatatgtt
//
LOCUS       DAVDHC010000030        24461 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVDHC010000030 DAVDHC010000000
VERSION     DAVDHC010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.030"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(54..530)
                     /locus_tag="VUR43_001686"
     CDS             complement(54..530)
                     /locus_tag="VUR43_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET5413344.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     TDPLYVWLKDHKSGPLGKRIEWNFAKFLISRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            753..3956
                     /locus_tag="VUR43_001687"
     CDS             753..3956
                     /locus_tag="VUR43_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET5413345.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSPEKLRAAVHRMVPIEAKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRIYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYKDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATLDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            4335..4720
                     /gene="tnpA"
                     /locus_tag="VUR43_001688"
                     /pseudo
     CDS             4335..4720
                     /gene="tnpA"
                     /locus_tag="VUR43_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(5099..5728)
                     /locus_tag="VUR43_001689"
     CDS             complement(5099..5728)
                     /locus_tag="VUR43_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET5413346.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASSACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(5738..6739)
                     /locus_tag="VUR43_001690"
     CDS             complement(5738..6739)
                     /locus_tag="VUR43_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET5413347.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(6770..7411)
                     /locus_tag="VUR43_001691"
     CDS             complement(6770..7411)
                     /locus_tag="VUR43_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET5413348.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(7430..8245)
                     /locus_tag="VUR43_001692"
     CDS             complement(7430..8245)
                     /locus_tag="VUR43_001692"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET5413349.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            8516..8950
                     /locus_tag="VUR43_001693"
     CDS             8516..8950
                     /locus_tag="VUR43_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET5413350.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVVAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            8962..10152
                     /locus_tag="VUR43_001694"
     CDS             8962..10152
                     /locus_tag="VUR43_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET5413351.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            10163..10654
                     /locus_tag="VUR43_001695"
     CDS             10163..10654
                     /locus_tag="VUR43_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET5413352.1"
                     /translation="MTMPNIVMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKVALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            10669..11448
                     /locus_tag="VUR43_001696"
     CDS             10669..11448
                     /locus_tag="VUR43_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET5413353.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFVFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            11435..12253
                     /locus_tag="VUR43_001697"
     CDS             11435..12253
                     /locus_tag="VUR43_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET5413354.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            12253..12546
                     /gene="yajC"
                     /locus_tag="VUR43_001698"
     CDS             12253..12546
                     /gene="yajC"
                     /locus_tag="VUR43_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET5413355.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIHVEKESVMGKTKELLFK"
     gene            12568..14469
                     /locus_tag="VUR43_001699"
     CDS             12568..14469
                     /locus_tag="VUR43_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET5413356.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPRSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            14529..15530
                     /locus_tag="VUR43_001700"
     CDS             14529..15530
                     /locus_tag="VUR43_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5413357.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(15640..15975)
                     /locus_tag="VUR43_001701"
     CDS             complement(15640..15975)
                     /locus_tag="VUR43_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413358.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(15986..16228)
                     /locus_tag="VUR43_001702"
     CDS             complement(15986..16228)
                     /locus_tag="VUR43_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413359.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(16239..16781)
                     /locus_tag="VUR43_001703"
     CDS             complement(16239..16781)
                     /locus_tag="VUR43_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET5413360.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADRIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(16797..16991)
                     /locus_tag="VUR43_001704"
     CDS             complement(16797..16991)
                     /locus_tag="VUR43_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5413361.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            17157..18107
                     /gene="rsmH"
                     /locus_tag="VUR43_001705"
     CDS             17157..18107
                     /gene="rsmH"
                     /locus_tag="VUR43_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET5413362.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            18119..18436
                     /gene="ftsL"
                     /locus_tag="VUR43_001706"
     CDS             18119..18436
                     /gene="ftsL"
                     /locus_tag="VUR43_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET5413363.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            18440..20692
                     /gene="pbpX"
                     /locus_tag="VUR43_001707"
     CDS             18440..20692
                     /gene="pbpX"
                     /locus_tag="VUR43_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET5413364.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            20694..21674
                     /locus_tag="VUR43_001708"
     CDS             20694..21674
                     /locus_tag="VUR43_001708"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET5413365.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTFAILYLM"
     gene            22238..24343
                     /locus_tag="VUR43_001709"
     CDS             22238..24343
                     /locus_tag="VUR43_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET5413366.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGCFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT         7510 a         4379 c         5475 g         7097 t
ORIGIN      
        1 aaatctcact attcatcagg ttaaaggaaa cctaatcata gtgagattgt gaattatagt
       61 agagtttgta tcgcctcttc aatttgtttt gggtctgttt ttgaagaaaa gcgttcaaag
      121 acttgcccat cacgactaat gagaaactta gcgaaattcc attcgattcg ttttcctagt
      181 gggccagatt tatggtcttt taaccagaca tagagagggt ctgtttcctt accgttgacc
      241 ttaatcttgg caaaacgtgg gaaggtggtt tgaaaatgta ggctacagaa ggcgttgatt
      301 tcctctgcgc tgccgggtgc ttgtcccata aactgattgc aagggaaatc caatatttcg
      361 aagccctgat cttgatagcg ttcatagagt tcttgaagtc cctggtactg gggcgttaaa
      421 ccacatccag tagcagtgtt gacaatcaag agaactttgc cacgatagct atccaaggga
      481 gttgcttggt tgttttggtt caaaacggaa aaatcataaa gtgaagtcat gagggcctct
      541 tttctttttc tacattgtaa cagtttttac ttttttcgtc gagtcggatg gaagatattg
      601 ttgaagaata agccctcaat atgatagaaa ccgtttacaa ataactttaa aaatggtatg
      661 atttaattaa accggtttac tttgttgcta taaatctcta atttgagatt tagttcctat
      721 tgattttaca atatgtttat tggagtgtat acatgcaaac aaaaacaaag aagctcattg
      781 tgagtttgtc ttcacttgtt ttatcaggat ttttattaaa ccattatatg acagttggag
      841 cggaagaaac gactacgaat accattcagc aaagccagaa ggaagttcag tatcagcaaa
      901 gggatacaaa aaatttagtt gaaaatggtg attttggtca gacggaggac ggaagcagtc
      961 cgtggacagg aagcaaagct caggggtggt cagcttgggt agaccagaag aatagttctg
     1021 cagatgcctc aactcgagtc attgaggcta aggatggggc tatcactatc tcaagccctg
     1081 agaaattaag ggcagcggtt caccgtatgg ttcctattga agctaagaaa aagtataaac
     1141 tgcgtttcaa gattaaaaca gataataaag tcgggattgc caaagttcgt atcattgagg
     1201 aaagtggtaa ggacaagcga ttgtggaatt ctgcaacgac gtcaggaaca aaggactggc
     1261 agaccattga agcagactat agcccgactt tagatgttga taaaatcaag ctggagttat
     1321 tctatgaaac aggaactggg actgtttcct ttaaggatat tgagctggta gaggtagcag
     1381 accagccttc tgaggattct caaacagata aacagcttga ggaaaagatt gatttaccaa
     1441 ttggaaaaaa acatgttttt tctcttgcgg actatactta taaggtagaa aatcctgacg
     1501 ttgcttcagt caaaaatgga attttagaac ctcttaagga agggacaacc aatgttattg
     1561 tcagtaaaga tggcaaggaa gtgaaaaaga ttcctttgaa gattctagcc tctgttaagg
     1621 atgcatacac agaccgtttg gatgactgga atggcatcat cgctgggaat caatactatg
     1681 attctaaaaa tgaacagatg gccaaattaa accaggaatt ggaaggaaag gtagctgata
     1741 gcctatccag tatttcaagt caggcggacc gcatctattt gtgggaaaaa ttttcaaatt
     1801 ataaaacgtc tgcaaatctg actgccactt atcggaaatt ggaggagatg gccaagcaag
     1861 tgaccaatcc ttcttctcgt tattataaag atgaaactgt cgttcgaaca gtcagggatt
     1921 ccatggaatg gatgcataaa catgtctaca atagtgaaaa gagcattgtt gggaactggt
     1981 gggattatga aatcggtaca cctcgtgcca tcaacaatac cttgtctctg atgaaagaat
     2041 acttctctga tgaggaaatt aaaaaatata cagatgtgat tgaaaaattt gtaccagatc
     2101 ccgaacattt ccgaaagacg actgataacc cattcaaggc tctaggtgga aacttagttg
     2161 atatgggaag ggtaaaagta atagctggtt tactgcgtaa ggatgatcaa gaaatttctt
     2221 ctaccattcg ctcgattgag caagtgttca agttggtaga ccaaggtgaa ggtttttatc
     2281 aagatggatc ctatatcgac cacaccaatg ttgcctatac gggtgcttat gggaatgttt
     2341 tgattgatgg cctgtctcaa ctgttgccag tcattcaaaa gaccaagaat ccaatcgata
     2401 aagataaaat gcaaaccatg taccactgga ttgataaatc gtttgctcct ttgctggtga
     2461 atggagagct gatggatatg agtcgtggac gctcgatcag tcgtgcaaat agcgaggggc
     2521 acgtggccgc agtagaagta ctaagaggga ttcaccgaat agcggatatg tctgaaggag
     2581 aaaccaaaca acgtttgcag agtcttgtga agaccattgt tcaatcggat agttattatg
     2641 atgtctttaa gaatttgaag acttataagg atatcagttt gatgcaatcc ttgttaagtg
     2701 atgcaggagt cgcaagtgtt ccaagaacaa gttacctatc tgcctttaac aagatggata
     2761 aaacagccat gtacaatgca gagaaagggt ttggatttgg cttgtcactc ttttccagtc
     2821 gtaccttgaa ttacgaacac atgaacaagg aaaataaacg tggttggtat acgagtgatg
     2881 ggatgttcta tctttacaat ggcgatttga gtcactatag cgatggctac tggccaacag
     2941 ttaatccata taagatgcct ggtacaacag agacggatgc taagagagcg gatagcgata
     3001 caggtaaagt tttaccgtct gctttcgttg gaacgagcaa actagatgat gccaatgcga
     3061 cagcaaccct ggatttcacc aactggaatc aaacattgac tgctcataag agctggttta
     3121 tgctaaagga taagattgcc tttttaggaa gcaatatcca aaacacttca acagatactg
     3181 ctgcaactac aatcgaccag agaaaactgg aatcaagtaa tccatataaa gtctatgtca
     3241 atgataaaga agcctccctt acagaacaag aaaaggatta tcctgaaacc caaagtgtct
     3301 ttttagaatc gtccgattcg aaaaagaata ttggttactt tttctttaag aagagttcaa
     3361 tcagtatgag taaggctttg caaaagggag cctggaagga tatcaatgaa ggacagtcag
     3421 acaaggaagt tgaaaatgaa tttcttacga ttagtcaggc tcataagcaa aatggagatt
     3481 cttatggcta tatgctcatt cctaacgtgg atcgtgccac cttcaatcaa atgataaaag
     3541 agttagaaag tagcctcatc gaaaataacg aaacccttca gtctgtttat gatgctaaac
     3601 aaggagtttg gggcattgtg aaatatgatg attctgtctc tactatttcc aaccaattcc
     3661 aagttttgaa acgtggagtc tatactattc gaaaagaagg ggatgaatat aagattgcct
     3721 actataatcc tgaaacccag gaatcagctc cagatcagga agtctttaaa aagctagagc
     3781 aagcagctca gccacaagta cagaattcaa aagaaaagga aaaatctgaa gaggaaaaga
     3841 accattcgga tcaaaagaat ctccctcaga caggagaagg tcagtcaatc ttggcaagtc
     3901 tagggttctt gctacttggg gcgttttatc tattccgtag aggaaagaac aactaatttg
     3961 ttcatcatct agatgaatta catgaaactg tggaaaatag aaaaaatccg aagaaggcca
     4021 aatatcttcg gatttttctt ttaaaaaagg ataagttgat acttatcctt tttacttcat
     4081 tatgtgacta tagcgttttg aaactagaat aggacgttat aactactaaa agatttctat
     4141 aaattcattt gattttccta atcaatttgt tcgtatccta tttcactcca ctatattagt
     4201 ccgtctcgct ccgtgaggtg cgagacaaaa caaccacccg ctatgcgggt gcgcgtcgaa
     4261 ggttatacca aaaaactcca aacgcgatac aataaaggtg ttcaatccaa ttgtaaagcg
     4321 aaaggagaaa aaatatggca caaaaggctc atagtttatc tcacacaaag tggaggtgtt
     4381 ctatcacatt gtgttcaccc ctaagtatag acgaaaagtc atctataatc aatatagaag
     4441 tagtttaggc gaaatatttc atcgcttgtg tagttataaa ggtgttgaaa tgatcgaggg
     4501 tcacttaatg ccagaccatg tacacatgtt agtcagtatt ccgtcgaggc taagtgtttc
     4561 aagttttatg gggtatttaa aaggcaaaag tgcactcatg atgtttgaca aacacgccaa
     4621 tctcaagtac aagtttggga atcggcattt ctgggcggaa ggttattatg taagtccagt
     4681 agggcttaat gaagacacaa ttaagaaata tagtcaagat taaagaaatt atcgagtgga
     4741 tgatttcttc acgagtatga aaatttgaga actagtaaag tatgatatat agtaaaatga
     4801 aataagaaca ggacaaaatc gatcaggaca gtcaaatcga tttttaacaa tgttttagaa
     4861 gtagaggtgt actattccag tttcaatcta ctatagcact agataaattg agtgtaaaag
     4921 aatatgagga tccctttagg gatagtggta agtaatacca aagtctctta aagaggcaag
     4981 tgacgagtca agagcaataa ggcttgaaca acgtgaaagc cagcgtcttt aggcgctggc
     5041 tgatgatttg ggcttatagc tctgagataa accacccgtt agacgggtag ttatgatttt
     5101 atctgagtgt aacatactgt tgggcaatct cgctgatgcg gtcaaagttg ccttgggaag
     5161 cgagtttatt gagttcgcca ccaattccaa cggcatctgc accagcagcg aaccattgag
     5221 ggatgttgtt taggccgact cctccggtta ccattacgga aacttgtggg atcggtgcct
     5281 tgactgcaga gatatatgct ggactgagag tactacctgg gaagagtttg atgatttcac
     5341 taccggcttc aagtgcagtc gtgatctctg tgagggtaat acagcctgga atgtacggtg
     5401 tgctgtagag attgcacatt ttcgcagttt cagcatggaa agatggagaa acaacgtaat
     5461 ttgctccagc tagaatggca tctctagcag ttacggcatc aagcacagta cctgcaccga
     5521 tacaaacact ctgatcgtcc tgatacaagt ctacaagttc cttgatgatt tgtcctgcat
     5581 actgattggt ataggcgatt tcaatagctt tgataccgcc cttgatacaa gcactcgagg
     5641 cttgtagtcc ttcttccttt gtatttcctc gaatgacagc gacaattttc tgttttttta
     5701 gttcaataat cgtatctgat ttggtcatgt aattctccta acgaatgata tcttgtgcat
     5761 ttgccagtaa attttcaata ctagttgcgg aagtggagag atggtctcct ggaagagtgc
     5821 atttgagagt tgcgctcgca actgcaaagt caatggtagt ttttagggag gaatgatgga
     5881 gtagttggta aagggcacca gatataaagg catccccgct accaattcgt tgatagactg
     5941 cagtttttag ttggacagac tcttcaaatc gttcttccag agcataggct tgatagacat
     6001 ttttgtcttg ctcatcacta gatcggaggg tatggaaaat agccttgaaa ccataggttt
     6061 cttttaaaag tcgcatgcga ttttccacct cttctaggct agcactgtct cttggaaaca
     6121 tctctagatt ttggtcatca atcatgagag gatcaatacc gaagcaatag tcagtaaaac
     6181 gtgcaaactt agaaaattca tacttggctt ctagggctga aatcatcttt gttctcagat
     6241 tgagatccat tgaaacgaca attcctcggc gcttggcttc ttccaagagt aggagaagga
     6301 tcgcacggac ctcttgaccg atagctatgg tgattccact aaaatgaaaa tggctaatcc
     6361 cctgaaagag agaatccata tctagcatgt ttggccgaat ctggctgata ctcgtatgct
     6421 tacgatcgta gaaaacttca ctttgacgac aaccaaagcc gttctccaaa tagtagaggc
     6481 cgattcgatc gccaagccga cagattgaac tggtatcgat ttggtgctgt ttcaagaatg
     6541 tgagaaaacg atctccaatc tcgttggcag ggagtgcggt aaagactttc gttgagatac
     6601 ccagggcttg caaattacaa gcgatgttaa tttctgatcc gccaaaataa gtcgaactgg
     6661 caacatgatc gccgatactg gtggcatcta atggtgagat tcgaattaat ggttcgccaa
     6721 acagtaatat tttcgtcatc cattagttcc tttctggttt agaatagctt tacttggcta
     6781 atacttcttt caaataagca gcgacttcat catcttggca gttttcaaag aagtattctt
     6841 ggaagtattt gccagagatg gtgtctttga ggaagtcttg gtcgattgtt ttaaggatgg
     6901 tcatcaaatc attgtgggtg atttgtttca cctcgtttaa gatacgagcg ttgcgttgtt
     6961 cagggattac acgttctctt gggtagccac cgcccatttc ttcagcaaat aagcgttcaa
     7021 acatcaattt gagggtcagt tctgcccccc agccaaatcc tttggcataa gggatagaca
     7081 aggcgttacc accattgatt tgagaataaa ggtaagcgtc agttgggtcc actgctagac
     7141 cacagacaac accagggaag ctgtttaaag caagcatagc ccctacaccc gtaccacagc
     7201 cggtaacaac aaagtcaact gcctttgtat ttaaaaggat ggcagccatt agtccgttct
     7261 gcacataagt taattgactt tctccttctt ctccacgcat accatagtta aataattggt
     7321 agtctttttt atctgtcgct tcttttagac tatcgtaaat aatgtgattc ttgctagctt
     7381 gactattttc attgattaat gcgattttca taagatcttc tttctatttt tactcaggtt
     7441 gttttccgat gtaggctaag ataccgccat ctacatatag gatgtggcca ttgacaaaat
     7501 tgctggcatc actagcgaga aagacagcag ggcccatcaa atcttcagga tttccccaac
     7561 gtgcagcagg tgtttttgca atgatgaact ggtcaaatgg gtggcgagaa ccatcttctt
     7621 gcaactcacg aagaggtgct gtttgaggag tggcaatata acctggtcca attccgttac
     7681 attggatatt ggctccaccg tattcagacg caatgttgcg ggtcaacatt ttcaagcccc
     7741 ctttagcagc agcataagcg ctaactgttt cacgtcccag ttcgctcatc atcgaacaaa
     7801 tattgataat ctttccatgc cctttcttta tcatagaagg aataactgcc tttgaaacga
     7861 taaatggtgc gtttaagtca atatcgatga ccttacggaa atcagcggcg ctcatttcgc
     7921 acattggaac tcggcggata ataccagcgt tattaacgag gatgtcaatg acaccaacct
     7981 cttgttcgat ttgcttgacc atggcttgga taccgtcctc gtctgtcacg tcacagacat
     8041 atccatgggc ttggatgcca acttcacgat aagcttcaat ccctttattg accagatctt
     8101 gattgatatc gttaaagaca atagtagcgc cggcttcagc gtaggatttg gcaatagcaa
     8161 atccaattcc ataagaagcg ccggtgatga gagcaatttt tccttttaaa gaaaactgct
     8221 caattgagaa tgatgtattt gtcatttgat acttcctttc aaatttgtta agacttctct
     8281 ataatcaaat tatattctag taaaccggtt ttgtcaataa ataaatattt ttatttataa
     8341 aaagatttat ttcccttaaa aatggaatat tttgaaattt ctgtctatta aaatgattaa
     8401 aaagataatg aaagcgctaa tattttttta aaaaaactat tgacaagata aaaataaagg
     8461 attacaatgg ggaatataaa gtaaaccggt aaacctaaac aagaaaggag aaaagatgaa
     8521 aattgtactt gtagggcatg gacattttgc tacagggatt tatagttctt tacaattgat
     8581 tgcaggtaat caagaaaatg tggaggcgat tgactttgtg gaaggaatgt cagcagatga
     8641 actcaagcaa aaaatcttac ttgcaatttc aaatgaagaa gaagttttaa tcctaagtga
     8701 tctcttggga ggatcgccat tcaaggtttc ttctaccata atgggagaaa atccagccaa
     8761 aacaatgaat gttctctcgg gtttgaactt agccatgtta atggaagcag tctttgctag
     8821 aatggctcat agctttgatg aggttgttaa taaatcagta gtggtggccc agggcggagt
     8881 cgtaaatggt aaagaattgt tttcaacgga tgcagaggaa gaggaagaag atttcgaatc
     8941 gggtatttaa agggtaaaag aatgataaaa aaggttacga ttgaaaaaat aaaatcgcct
     9001 gagcgcttct tagaagtacc acttctgacg aaagaagaag tcggccaggc aatcgataag
     9061 gttattcggc agttagaact caaccttgac tatttcaagg aagatttccc gacaccagct
     9121 acctttgata atgtctatcc aatcatggat aacacggaat ggaccaatgg tttctggaca
     9181 ggagaactgt ggttggctta tgaatacagt caacaggatg catttaaaaa catcgctcat
     9241 aaaaatgttc tttctttcct ggatcgtgtc aataagagag tagaattgga tcaccatgat
     9301 ctcggcttct tgtacacacc gtcttgtatg gctgaatata agataaatgg agatggagag
     9361 gctagagaag caaccttgaa agctgcagat aagttgattg aacgctatca agaaaaaggt
     9421 ggttttattc aagcttgggg agacttgggc aagaaagagc attaccgttt gattatcgac
     9481 tgcttgctca atatccaact cttattcttt gcttatcaag aaacaggcga tcaaaaatac
     9541 tacgatattg cagaaagtca tttctatgct tcagctaata atgtaatccg tgatgacgct
     9601 tcgtccttcc acaccttcta ttttgatcct gagacaggtc aaccctttaa aggtgtaacg
     9661 agacaagggt atagtgatga ttcatgctgg gcacgtggtc aatcatgggg agtctatggt
     9721 attcctttga cttatcgtca cttaaaagac gagtcctgct ttgacttgtt taagggtgtg
     9781 accaattatt tcttgaatcg tctgccaaaa gatcatgtgt cctattggga tttgattttt
     9841 aatgatggta gtgctcaatc acgagattct tcagcaacag ctatcgccgt ctgtgggatt
     9901 catgaaatgc taaaacatct cccagaggtg gatgctgaca aagatattta taaacatgct
     9961 atgcatgcca tgcttcgttc cttgatcgaa cattatgcaa atgatcaatt tacccctggt
    10021 gggacaagtc tcctccacgg tgtgtactca tggcattcag gtaaaggagt ggatgaaggc
    10081 aatatctggg gtgactacta ttacctagaa gcccttatcc gtttctacaa agactggaac
    10141 ctatattggt aggaggagaa atatgacaat gccaaatatt gttatgaccc gtatcgatga
    10201 acggttgatt catggacaag gacaactttg ggtaaaatac ctaggttgta atacggtcat
    10261 tgttgccaat gacgaagtaa gcacggacaa gatgcaacaa actctgatga aaacagttgt
    10321 gccagactca gttgccatgc gtttcttccc tttgcaaaag gtgattgata tcattcacaa
    10381 ggctaatcct gctcaaacga tctttatcgt tgtaaagaat gtgaaggatg ctttaacctt
    10441 ggtagaaggt ggtgtcccta tcaaagaaat caatattggg aacattcaca atgctactgg
    10501 taaagagcaa gtgacacgct ccatcttcct gggtgaagag gacaaggtgg ccctcaagga
    10561 attgagccaa actcatcaag taacatttaa tacgaaaaca actccaacag gaaatgatgg
    10621 agctgttcaa gtcaacatta tggactatat ttaaaagagg agatcgttat gtcgattaat
    10681 gtatttcaag cgattttaat tggattatgg acagctttct gttttagtgg aatgctgtta
    10741 ggaatttaca ccaatagatg tattgttctg tcatttggtg tcggaattat tctaggtgat
    10801 ctgcctactg ctcttgcaat gggagctatt ggtgaattgg cttatatggg attcggtgtt
    10861 ggtgctggag gtactgttcc accaaaccca atcggacctg gtatctttgg taccttgatg
    10921 gctatcacta gtgctggtaa agtcagtcca gaagcggctc ttgccctctc tactccgatt
    10981 gctgtggcga ttcaattctt acaaactttc gcctacactg tacgtgctgg tgcgcctgaa
    11041 acggcgatga agcacttgaa aaaccataat ttgaagaaat tcaagttcac tctaaatgca
    11101 acaatttggt tgtttgtctt tattggattt accttgggtt gcttgggcgc cctttcaatg
    11161 gataccttgt tgaaactcgt agactacatt ccaccggtat tgcttacagg tttgacagtt
    11221 gctggtaaaa tgctcccagc tatcggtttt gcgatgatct tgtcagtgat ggctaagaaa
    11281 gagttgattc cctttgtctt gttgggatat gtttgtgcag cttatctaaa catcccaaca
    11341 attggtattg caattgtagg tactatcttt gctttgattg aattttataa caagccaaaa
    11401 acagcggatc atgtggtaga ggaggaagca cacgatgact ggatctaaca aattaacaaa
    11461 acgtgattat cttaaaacgt ctttgcgggc attcttttgt caaaatggat ttaactatag
    11521 taactatcaa gggttgggat atgccaatgt gatgtatcct gctttgaaaa aacactatgg
    11581 agaggatcag gaaggtttct accaagcctt ggaagaaaac tgtgaattct ataataccaa
    11641 tccacacttc ctgcctttta ttaccagctt gcaccttgta atgttggaaa atggccgacc
    11701 aacaaaagaa acacgtagca tcaagatggc cttgatggga ccattagcag gtattgggga
    11761 ttctctctct caattctgtt tagctccatt gttctcaacc atcgcagctt cgtttgctca
    11821 agaaggcttg gttgtcggtc caatcttgtt cttccttgcg atgaatacga ttttaacagc
    11881 gattaaattg tcaactggtc tgtatggata caaactagga acaactgtga ttgataaact
    11941 aagcgaacag atggcaacga tttctcgtat tgccaatatt atcggtgtaa ccgtaattgc
    12001 tggtttggca gcgacatctg ttaagattat ggtgccgatt acctttgctg caggggaagt
    12061 taaagcagac gctaaacaaa gtatcgtaag tattcaggga atgcttgata aggttgctcc
    12121 agctcttcta ccagccctat ttacactttt agtttactac ttgatcaaag aaaagaaatg
    12181 gacaacatat aaactcgtta ttttaacagt tatcatcgga attatcggaa gctggcttaa
    12241 gattatagct taatggatac aacattgttt tatggaatag tgattgtctt ggcagtgagt
    12301 ccccttttac tgtcaagctt tcattctatt cgtcagcaaa agttgcttcg caaacagatg
    12361 gagcaacgac aagagtattt agcttcttta acatctggtg atgaagtgtt gttattgtct
    12421 ggaattcatg gaaaaatcat ttctatccaa gatgacttgg tctccttgca gattgcaaaa
    12481 ggtgtggtca tccatgtaga aaaggaaagt gtaatgggaa agacaaaaga actgcttttt
    12541 aagtagttct ttttctggta atagataatg aaagaagaaa gaagacaatt ttttgaaaga
    12601 atcgatggaa accaatgtcg tgattatatc ttgtcgcact gttcaaaaga ctatgagaaa
    12661 gtcaagagtt cccttgaacg cttgatggac aatcgtttta tgtttgatag tccttgggat
    12721 atggagcctt gttcaaaaat ccatcaaatc caaccgatgg tatgggatca agtatttgaa
    12781 gatgatccag aatgggctta tatgctcaat cgacaagaat atctcttgca gtttatgata
    12841 gggtatgtgg tagaaggaga taaggactat attcaaaagt gcaagttctt tctatttgat
    12901 tggattgagc aggtgagaga attttctcct caatccttga tgactagaac cttggatacg
    12961 ggtattcgtt cctttacttg gttgaaacta ctcttgctcc tcttgaaatt tgacttgcta
    13021 gaggagaaag aactagagaa aattttggtc agtctagaaa agcagattga ctttatgaaa
    13081 agccactatc gcgccaagta cacccttagt aactggggaa ttttacaaac aattccgatg
    13141 cttgctatct atcatttctt tgcagataag atggacctag aagaagctta ccattttgct
    13201 tcagaggagt tgaaacagca aattgagaca cagattttag gagatggaag ccagtttgaa
    13261 cagtcgattc tctatcatgt agaggtttat aaagccttgc tggatttgtg tctcttgctt
    13321 ccagacttgc aagatagtta ccaagagttg ctggaaaaga tggcgaccta tattcaaatg
    13381 atgacaggct tagatggacg aactttggct tttggtgata gcgattctac agaaacgaca
    13441 gaaatgttga gcctgtctgc tgtggttttg aacaaggaag accttcttaa cggtctggat
    13501 gttaaagtcg atttgcttag cctcttgttc ctggggcgag aaaaggtcaa gcgactgcag
    13561 gaatttgaaa agagagcttg gcagcctagg tccatgatct ttgaagactc tggacatgtc
    13621 tgcattaagg atgaacatcg ttatctattt ttcaaaaatg gtccgctagg aagtgcccat
    13681 agccatagtg acgagaatag tttttgctta cagtatcaag gccaacctat tttcatagat
    13741 gctgggcgtt attcttatcg ggagatatat gaacgttatc tcttaaagag tgcttggagt
    13801 cattcgacct gcattgtaga tgggaaagct ccggaaagaa tcacgggatc ctgggaatat
    13861 gaatactatc ctcactccct gttttgtcac cataaagaaa gggagggagt gcattatatt
    13921 gaaggggctt attggtcagc agaacctgat ttgccttatc ttcacaagag aaaaatcctc
    13981 atgttggtag aggatgtctg gctcttggta gatgacatca ggtgtcaagg tcagcatgag
    14041 gcgttgactc agtttatcct tgacaaggat gtgacctatc aagatgggaa aatcaatcag
    14101 ttgagactat ggagtgaagt tgattttgat ttggaagata ccatcatttc tcctaaatac
    14161 aatgagcttg aaagaagtaa caaactcacc aagcgccaat tctttgagaa tcagatgctg
    14221 gattatacca tcattgcgca tgagagtttt gaaatcatcc gtcattctgt ctaccagaca
    14281 gatgatcgtg aagtggaaaa tgctctggct tttgaagtga aaaatgacga aacagacaag
    14341 ctgattctgt tattaagcga ggatatttgt gtaggtgaaa aattgtgcct cgttgacgga
    14401 acaaaaatgc gtggaaaatg tctagtatat gataaaataa atgagagaat gattcgcttg
    14461 cagtgctaga aataggcatt ttgaatagtg aatatgttat aataagtatt agtaggaggt
    14521 gttttagatt ggagaagaaa ctgaccataa aagacattgc ggaaatggct cagacctcga
    14581 aaacaaccgt gtcattttac ctaaacggga aatatgaaaa aatgtcccaa gagacacgtg
    14641 aaaagattga aaaagttatt catgaaacaa attacaaacc gagcattgtt gcgcgtagct
    14701 taaactccaa acgaacaaaa ttaatcggtg ttttgatcgg tgatattacc aacagtttct
    14761 caaaccaaat tgttaaggga attgaggata tcgccagcca gaatggctac caggtaatga
    14821 taggaaatag taattacagc caagagagtg aggaccggta tattgaaagc atgcttctct
    14881 tgggagtaga cggctttatt attcagccga cctctaattt ccgaaaatat tctcgtatca
    14941 tcgatgagaa aaagaagaaa atggtctttt ttgatagtca gctctatgaa caccggacta
    15001 gctgggttaa aaccaataac tatgatgccg tttatgacat gacccagtcc tgtatcgaaa
    15061 aaggttatga gcattttctc ttgattacag cggatacgag tcgtttgagt actcggattg
    15121 agcgggcaag tggttttgtg gatgctttaa cagatgctaa tatgcgtcac gccagtctaa
    15181 ccattgaaga taagcatacg aatttggaac aaattaaaga atttttacaa aaagaaatcg
    15241 atcccgatga aaaaactctg gtatttatcc ctaactgttg ggccctacct ctagtcttta
    15301 ccgttatcaa agagttgaat tataacttgc cgcaagttgg gttgattggt tttgacaata
    15361 cggagtggac ttgcttttct tctccaagtg tttcgacgct ggttcagccc tcctttgagg
    15421 aaggacaaca ggctacaaag attttgattg atcagattga aggccgcaat caagaagaaa
    15481 ggcaacaagt cttggattgt agtgtgaatt ggaaagagtc gactttctaa aatgaaggaa
    15541 aatgacttgc aatttctgtt aagaaataaa ataatcccac ctagaacaag ctaggtggga
    15601 ttatttgcct atgaaatgag aaattatggg agcaagctcc taaatcaact gtttttgatc
    15661 tacttcttta actacttgat aaaagttata gaagtaggcc aaacttgaaa tgatggttac
    15721 gactaggaat attgaaaatt tccattggac agggttggtt aaaagttgtg gaaaggatat
    15781 gaggagaaag aagagggctg cgttgaggac aggtatccgt tttgattgta ttttctcaag
    15841 tcctttattg agcgcaggaa gaaagaggag taggagtagt aaaactgtat gagaaatagc
    15901 tcctgaagta agggcgaaga aaaggaaaat actgataaaa acatgaatga tcagtagtct
    15961 agctagtgat ttcataaggc acctcctaat cctggtcttt tttagctctt gcaatacgaa
    16021 gtgagtcgac aatatgtatc atcactccga aaaagaaagc tcccagtata gttttaaaaa
    16081 tatgttttgt atttagaaga gaactgataa aatttggatt ttcacttgtt agggtatcaa
    16141 tgagtggaat tataaaaaat atcactgttc cataaatcga acctgctttc agaccaggat
    16201 aacgtaactg tttcttttct tttttcatga gtttcctcct aatcctcatc ttgatttttc
    16261 ttagtttttg caatgcgacg ggagatgagg aactgtatgc tcgctccgaa gaaaatagaa
    16321 ccgagaatac ttgatacacc atttcttata gtgagaagag aatgaaaata gtcctgacct
    16381 tcatctatga gtatactgag aagaggagtt ataaaaaaca tccatagacc aaagaacaaa
    16441 cctgctttca gaccagggta gtgtagttgc ttgctttctt tctcattcag catatctggt
    16501 tcaatgactg tgatgcctgt ttttttcatt tggtaggtga catagccaga agcgatgagg
    16561 gcaatcacta aaatcagagg aggatagatt agagccactt cttgagggta tttataggcc
    16621 agaaggagtg gaataatatt tccgaaaatc atcagataaa agaggacgat aaagacttgg
    16681 ttcccaatac gatcggcctc acgccgtttg tattcgtcaa ggggaccaga aataccgtat
    16741 gtgcgtttga tcagtttttc agtgaaggtt tcttttttca tgagtttgct ccttttttaa
    16801 aaatcttcct cccaaaagag actgttgagg tcagtttgga ggctgcgggc gagattgaga
    16861 cagagttcca aggttggatt gtacttgtcg ttttcaatca tattgatagt ctgtctcgag
    16921 acaccgatat ccttggcgag ttcgagctgg gaaataccca attccttgcg aaattctttc
    16981 acacgattca tctggtctcc tttctgattt atgtcgtata tatttgacta tattatagtc
    17041 ttttaaacat aaagtgtcaa gtatttttga catatttttt gaagaaatag tagtctcctt
    17101 gtcctatttg tctgacaagt gcaagctggt cggatttgtg gtaaaataga taagatatga
    17161 caaaagaatt tcatcatgta acggtcttac tccacgaaac gattgatatg cttgacgtaa
    17221 aacctgacgg tatctacgtt gatgcgactt tgggtggagc aggccatagc gagtatttat
    17281 taagtaaatt aagtgaaaaa ggccatctct atgcctttga ccaggatcag aatgccattg
    17341 acaatgcgca aaaacgcttg gcaccttaca ttgagaaggg aatggtgacc tttatcaagg
    17401 acaacttccg tcatttacag gcacgtttgc gcgaagctgg tgttcaggaa attgatggaa
    17461 tttgttatga cttgggagtg tctagtcctc aattagacca gcgtgagcgt ggtttttctt
    17521 ataaaaagga tgcgccactg gacatgcgga tgaatcagga tgctagtctg acagcctatg
    17581 aagtggtgaa caattatgac tatcatgact tggttcgtat tttcttcaag tatggagagg
    17641 acaaattctc taaacagatt gcgcgtaaga ttgagcaagc gcgtgaagtg aagccgattg
    17701 agacaacgac tgagttagca gagattatca agttggtcaa acctgccaag gaactcaaga
    17761 agaaggggca tcctgctaag cagattttcc aggctattcg aattgaagtc aatgatgaac
    17821 tgggggcggc agatgagtcc atccagcagg ctatggatat gttggctctg gatggtagaa
    17881 tttcagtgat tacctttcat tccttagaag accgcttgac caagcaattg ttcaaggaag
    17941 cttcaacagt tgaagttcca aaaggcttgc ctttcatccc agatgatctc aagcccaaga
    18001 tggaattggt gtcccgtaag ccaatcttgc caagtgcgga agagttagaa gccaataacc
    18061 gctcgcactc agccaagttg cgcgtggcca gaaaaattca caagtaagag ggaaaaagat
    18121 ggcagaaaaa atggaaaaaa caggtcaaat actacagatg caacttaaac ggttttcgcg
    18181 tgtggaaaaa gctttttact tttccattgc tgtaaccact cttattgtag ccattagtat
    18241 tatttttatg cagaccaagc tcttgcaagt gcagaatgat ttgacaaaaa tcaatgcgca
    18301 gatagaggaa aagaaaaccg aattggacga tgccaagcaa gaggtcaatg aactattacg
    18361 tgcagaacgt ttgaaagaaa ttgccaattc acacgatttg caattaaaca atgaaaatat
    18421 tagaatagcg gagtaagata tgaagtggac aaaaagagta atccgttatg cgaccaaaaa
    18481 tcggaaatcg ccggctgaaa acagacgcag agttggaaaa agtctgagtt tattatctgt
    18541 ctttgttttt gccatttttt tagtcaattt tgcggtcatt attgggacag gcactcgctt
    18601 tggaacagat ttagcgaagg aagctaagaa agttcatcaa accacccgta cagttcctgc
    18661 caaacgtggg actatttatg accgaaatgg agtcccgatt gctgaggatg caacctccta
    18721 taatgtctat gcggtcattg atgagaacta taagtcagca acgggtaaga ttctttacgt
    18781 agaaaaaaca caatttaaca aggttgcaga ggtctttcat aagtatttgg acatggaaga
    18841 atcctatgta agagagcaac tctcgcaacc taatctcaag caagtttcct ttggagcaaa
    18901 gggaaatggg attacctatg ccaatatgat gtctatcaaa aaagaattgg aagctgcaga
    18961 ggtcaagggg attgatttta caaccagtcc caatcgtagt tacccaaacg gacaatttgc
    19021 ttctagtttt atcggcctag ctcagctcca tgaaaatgaa gatggaagca agagcttgct
    19081 gggaacctct ggaatggaga gttccttgaa cagtattctt gcagggacag acggcattat
    19141 tacctatgaa aaggatcgtc tgggtaatat tgtacccgga acagaacaag tttcccaacg
    19201 aacgatggac ggtaaggatg tttatacaac catttccagc cccctccagt cctttatgga
    19261 aacccagatg gatgcttttc aagagaaggt aaaaggaaag tacatgacag cgactttggt
    19321 cagtgctaaa acaggggaaa ttctggcaac aacgcaacga ccgacctttg atgcagatac
    19381 aaaagaaggc attacagagg actttgtttg gcgtgatatc ctttaccaaa gtaactatga
    19441 gccaggttcc actatgaaag tgatgatgtt ggctgctgct attgataata atacctttcc
    19501 aggaggagaa gtctttaata gtagtgagtt aaaaattgca gatgccacga ttcgagattg
    19561 ggacgttaat gaaggattga ctggtggcag aatgatgact ttttctcaag gttttgcaca
    19621 ctcaagtaac gttgggatga ccctccttga gcaaaagatg ggagatgcta cctggcttga
    19681 ttatcttaat cgttttaaat ttggagttcc gacccgtttc ggtttgacgg atgagtatgc
    19741 tggtcagctt cctgcggata atattgtcaa cattgcgcaa agctcatttg gacaagggat
    19801 ttcagtgacc cagacgcaaa tgattcgtgc ctttacagct attgctaatg acggtgtcat
    19861 gctggagcct aaatttatta gtgccattta tgatccaaat gatcaaactg ctcggaaatc
    19921 tcaaaaagaa attgtgggaa atcctgtttc taaagatgca gctagtctaa ctcggactaa
    19981 catggttttg gtagggacgg atccggttta tggaaccatg tataaccaca gcacaggcaa
    20041 gccaactgta actgttcctg ggcaaaatgt agccctcaag tctggtacgg ctcagattgc
    20101 tgacgagaaa aatggtggtt atctagtcgg ggtaaccgac tatattttct cggctgtatc
    20161 gatgagtccg gctgaaaatc ctgattttat cttgtatgtg acggtccaac aacctgaaca
    20221 ttattcaggt attcagttgg gagaatttgc caatcctatc ttggagcggg cttcagctat
    20281 gaaagactct ctcaatcttc aaacaacagc taaagctttg gagcaagtaa gtcaacaaag
    20341 tccttatcct atgcctagtg tcaaggatat ttcacctggt gatttagcag aagaattgcg
    20401 tcgcaatctt gtacaaccca tcgttgtggg aacaggaacg aagattaaaa acagttctgc
    20461 tgaagaaggg aagaatcttg ccccgaatca gcaagtcctt atcttatctg ataaagcaga
    20521 ggaagttcca gatatgtatg gttggacaaa ggagactgct gagacccttg ctaagtggct
    20581 caatatagaa cttgaatttc aaggttcggg ctctactgtg cagaagcaag atgttcgtgc
    20641 taacacagct atcaaggaca ttaaaaaaat tacattaact ttaggagact aatatgttta
    20701 tttccatcag tgctggaatt gtgacatttt tactaacttt agtaggaatt ccggccttta
    20761 tccaatttta tagaaaggcg caaattacag gacagcagat gcatgaagat gtcaaacagc
    20821 atcaggcaaa agctgggact cctacaatgg gaggtttggt tttcttgatt acttctgttt
    20881 tggttgcttt ctttttcgcc ctatttagta gccaattcag caataatgtg ggaatgattt
    20941 tgttcatctt ggtcttgtat ggcttggtcg gatttttaga tgactttctc aaggtctttc
    21001 gtaaaatcaa tgaggggctt aatcctaagc aaaaattagc tcttcagctt ctaggtggag
    21061 ttatcttcta tcttttctat gagcgcggtg gcgatatgct ttctgtcttt ggttatcaag
    21121 tgcatctagg gattttctat attgtcttcg ctcttttctg gctagtcggt ttttcaaacg
    21181 cagtaaactt gacagacggt gttgacggtt tagctagtat ttccgttgtg attagtttgt
    21241 ctgcctatgg agttattgcc tatgtgcaag gtcagatgga tattcttcta gtgattcttg
    21301 ccatgattgg tggtttgctc ggtttcttca tctttaacca taagcctgcc aaggtcttta
    21361 tgggtgatgt gggaagtttg gccctaggtg ggatgctggc agctatctct atggctctcc
    21421 accaagaatg gactctcttg attatcggaa ttgtgtatgt ttttgaaaca acttctgtta
    21481 tgatgcaagt cagttatttc aaactgacag gtggtaaacg tattttccgt atgacgcctg
    21541 tacatcacca ttttgagctt gggggattgt ctggtaaagg aaatccttgg agcgagtgga
    21601 aggttgactt cttcttttgg ggagttgggc ttctagcaag tctcctgacc ttcgcaattt
    21661 tgtatttgat gtaagaatgg caccctgatg tttcagggtg tttttgtgtt taaatacaca
    21721 atgaaaatca aagaacaaac tagaaagcta actttaggct gctcaaaaca tagtagtttg
    21781 aaactagaat agtacacatc tacttctaaa atattgttag aaatcgattt gactgtcctg
    21841 atcgatttgt cctgttctta tttcatttta atatacagtt ttgaggttgt agataaggag
    21901 aagctgatgt ggtttgaaga ggttttcgaa gagtgtaaaa aaatattggt cagttaaagt
    21961 caaaactatt gaccttttct gaccaatgta gtatattatg aacgtaaggt aaatgaaagc
    22021 cttactagaa cacttattta aagtaaaata gaaagaggtg ggtctatgtt tcatctagaa
    22081 atcttcagaa gtaaagatgg tctactcctg cttgaaaaag aaaaaccaga aatagtacgt
    22141 agggtagcgg tttaactagt ctaaattttt taaaacaatg gtcaaagata gtcaatatca
    22201 gtaatcataa ctaagtaaac aaaaagaggt aaagaatatg aataacaact ttaataattt
    22261 taataacatg gatgatttat ttaaccaatt gatgggtggt atgcgaggat atagttctga
    22321 aaatcgccgt tacttaatta atggacgcga agtcacacct gaggaatttg ctcactatcg
    22381 tgcgactggt caattaccag gaaatgcaga aactgatgtg caaatgccac aacaggcatc
    22441 aggtatgaaa caagacggtg tccttgcaaa actaggtcga aacttgacag cagaagcgcg
    22501 tgagggcaag ttggatcctg ttatcggacg aaacaaggaa attcaagaaa catctgaaat
    22561 cctctcacgc cgcaccaaga acaatcctgt tttggtcgga gatgcaggtg ttggtaagac
    22621 agcagttgtc gaaggtctag cgcaagccat tgtgaacgga gatgttcctg ctgctatcaa
    22681 gaacaaggaa attatttcta ttgatatctc aggtcttgag gctggtactc aataccgtgg
    22741 tagctttgaa gaaaatgtcc aaaacttagt caatgaagtg aaagaagcag ggaatattat
    22801 cctcttcttt gatgaaattc accaaattct tggtgctggt agcactggtg gagacagtgg
    22861 ttctaaaggg cttgcggata ttctcaagcc agctctctct cgtggagaat tgacagtgat
    22921 tggggcaaca actcaagacg aataccgtaa caccatcttg aagaatgctg ctcttgctcg
    22981 tcgtttcaac gaagtgaagg tcaatgctcc ttcggcagag aatactttta aaattcttca
    23041 aggaattcgt gacctctatc aacaacacca caatgtcatc ttgccagacg aagtcttgaa
    23101 agcagcggtg gattattctg ttcaatacat tcctcaacgt agcttgccag ataaggctat
    23161 tgaccttgtc gatgtaacgg ctgctcactt ggcggctcaa catccagtaa cagatgtgca
    23221 tgctgttgaa cgagaaatcg aaacggaaaa agacaagcaa gaaaaagcag ttgaagcaga
    23281 agattttgaa gcagctctaa actataaaac gcgcattgca gaattggaaa ggaaaatcga
    23341 aaaccacaca gaagatatga aagtgactgc aagtgtcaac gatgtggctg aatctgtgga
    23401 acgaatgaca ggtatcccag tatcgcaaat gggagcttca gatatcgaac gtttgaaaga
    23461 tatggctcat cgcttgcaag acaaggtgat tggtcaagat aaggccgtag aagttgtagc
    23521 tcgtgctatc cgtcgtaacc gtgctggttt tgatgaagga aatcgcccaa tcggctgctt
    23581 cctctttgta gggtctactg gggttggtaa gacggaactt gctaagcaat tggcactcga
    23641 tatgtttgga acccaggatg cgattatccg tttggatatg tctgaataca gtgaccgcac
    23701 agctgtttct aagctaattg gtacaacagc aggctatgtg ggttatgatg acaatagcaa
    23761 taccttaaca gaacgtgttc gtcgcaatcc atactctatc attctcttgg atgaaattga
    23821 aaaggctgat cctcaagtta ttacccttct cctccaagtt ctagatgatg gtcgtttgac
    23881 agatggtcaa ggaaatacag taaatttcaa gaacactgtc attattgcga cctcaaatgc
    23941 tggatttggc tatgaagcca acttgacaga agatgcggat aaaccagaat tgatggaccg
    24001 tttgaaaccc ttcttccgtc cagaactcct caaccgcttt aatgcagtca tcgagttctc
    24061 acacttgact aaggaagacc tttctaagat tgtagatttg atgttggctg aagttaacca
    24121 aaccttggct aagaaagaca ttgacttggt agtcagtcaa gcggctaaag attatatcac
    24181 agaagaaggt tacgacgaag tcatgggggt tcgtcctctc cgtcgagtgg ttgaacaaga
    24241 aattcgtgat aaggtgacag acttccactt ggatcattta gatgctaaac atctggaagc
    24301 agatatggaa gatggcgttt tggttattcg tgagaaagcc taagacagaa ttttgaggat
    24361 aaaaaagaag gagccagctg aaaaaaactg gttccttttt aggtacgacg ggcatgtcgt
    24421 gtagtagaag tgtactattc tagtttcaat atactatagt a
//
LOCUS       DAVDHC010000031        24237 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVDHC010000031 DAVDHC010000000
VERSION     DAVDHC010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.031"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(153..5456)
                     /locus_tag="VUR43_001710"
     CDS             complement(153..5456)
                     /locus_tag="VUR43_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET5413367.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVANKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTKNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELAVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGKFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSIVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTSLFLASVSLALSALFVVKTKKD"
     gene            complement(5757..7739)
                     /locus_tag="VUR43_001711"
     CDS             complement(5757..7739)
                     /locus_tag="VUR43_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET5413368.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSIKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVVIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            complement(7938..8096)
                     /locus_tag="VUR43_001712"
     CDS             complement(7938..8096)
                     /locus_tag="VUR43_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HET5413369.1"
                     /translation="MSLLETAKRHQLNSEKYLFYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(8167..8613)
                     /locus_tag="VUR43_001713"
                     /pseudo
     CDS             complement(8167..8613)
                     /locus_tag="VUR43_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8689..9123)
                     /locus_tag="VUR43_001714"
     CDS             complement(8689..9123)
                     /locus_tag="VUR43_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5413370.1"
                     /translation="MLLVLVSLAHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(9199..10050)
                     /gene="rfbD"
                     /locus_tag="VUR43_001715"
     CDS             complement(9199..10050)
                     /gene="rfbD"
                     /locus_tag="VUR43_001715"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HET5413371.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGRELDFAINVTGTKNVAKASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            complement(10116..11165)
                     /gene="rfbB"
                     /locus_tag="VUR43_001716"
     CDS             complement(10116..11165)
                     /gene="rfbB"
                     /locus_tag="VUR43_001716"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET5413372.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAVD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(11178..11771)
                     /locus_tag="VUR43_001717"
     CDS             complement(11178..11771)
                     /locus_tag="VUR43_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018029578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET5413373.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKNHPLLKDVKPLKKEDL"
     gene            complement(11772..12641)
                     /gene="rfbA"
                     /locus_tag="VUR43_001718"
     CDS             complement(11772..12641)
                     /gene="rfbA"
                     /locus_tag="VUR43_001718"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET5413374.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFKELLQDGSEFGIKLSYAEQPSPDGLAQAFIIGEEFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAKKEKGATVFGYHVKDPERFGVVEFDENMNAISIEEK
                     PEYPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(13136..14554)
                     /locus_tag="VUR43_001719"
     CDS             complement(13136..14554)
                     /locus_tag="VUR43_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413375.1"
                     /translation="MAMKLKFLITNLFHVFLSNLITIVTSVIVVLILPKIMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYQNLDKKQFYSQILQFFSFLILISFLLF
                     GFNLLIVTDPNAKYIYNMTIISMIVTNLRMLFVYILQMTNRLKDSSIILISDRVIYIF
                     LLFLFIIFKWHEYKVMIWADVLGRTFSLLLSFWICKDIVFQSLSEFILDLRESFDNIR
                     VGINLMLSNIASSMIIGIVRMGIQWNWNIETFGKVSLTLSISNLLMTFINAIGLVVFP
                     LLKRTKTENLSKIYSNLRNVLMLIMFAILLFYYPLKIILDLWLPAYRDALIFMALIFP
                     MSIYEGKMALVINTYLKALRMERDILKINTLIMLFSMLVTLITTLLLNNLELTVISIV
                     VLLALRSIIAELILSKKLDISVEQDIVLELLMTIIFISSSWYLPIWLAVIVYLLAYTL
                     YLYLKRKDTKMYIEYFRKKIFE"
     gene            complement(14673..16016)
                     /locus_tag="VUR43_001720"
     CDS             complement(14673..16016)
                     /locus_tag="VUR43_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000925815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET5413376.1"
                     /translation="MLLNFLFISIFLLIIITFILFEGDFFQPAVILTIAYFISIASAL
                     VNRNVWGTELHFKTFYLILLGVVTFVIVSLLTKLSYRPKVEGISHEELKEINPSKIIY
                     VILLTLNLVMLFLYIREIQKVVLFSGRSFSNITDLISNYRYLSYYSNEVENRVSGMIN
                     QLSKIIPATTLISLYIFMNNYFITKQIKKNFIYLIPIAIFFVYAIISGGRLPLIRLVV
                     GALLILYIYSVYGSPKSQLTKSFKMITRSLFTFLILIVLFFLLKFVLGRSSQEDFISY
                     ITRYMGGSIQLFDLFVIDPIRRNKELGAETFSGIYEMLAKLGFDNNIIKGLEWRVSPN
                     YYSLGNVYTAIRRYYSDFGVIGIVICQSFTAWLYTLGYEKVRHYSLVTNVQRFRLILL
                     AASFYPIFLNGIEDVFYISMVTIGYGIQIVIFYLVFWVLLKVQVDFNKGKLTINR"
     gene            complement(16016..17002)
                     /locus_tag="VUR43_001721"
     CDS             complement(16016..17002)
                     /locus_tag="VUR43_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5413377.1"
                     /translation="MGKSVAILMTTYNGERYLSQQIDSIRSQTFTNWTLFIRDDGSKD
                     KTIEVIQRYSKIDDRIRFVENPSKFHGAYYNFFNLIEYVKNNYQFDYYFFCDQDDIWK
                     EHKLEIQLLRFSKDDMPEMVYSDMSTIDASNNLIDISINKIMGIELPNINNLYFIHAY
                     IWGCTAGFNHALLEMVPSVDIDKDYLYIEKLSHDNYFAKFALEYGKVLFCPEQLVLYR
                     RHGHNVTTSHHFKLSPLNVFRKAILGFNELALTHAGVYNQTLYMLKKASGKNPLSDRL
                     LEIQEVIKIGGLKGVRYFYQNRISRKQLVRTIGLYTIMLFGTYKKYIMKELL"
     gene            complement(17005..17724)
                     /locus_tag="VUR43_001722"
     CDS             complement(17005..17724)
                     /locus_tag="VUR43_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HET5413378.1"
                     /translation="MSIYRICKDIERKTMSPAKKAMAKNDYFAFYVGRPLSYLLTVPF
                     VKTNITPNQISYLSIIPLIVGFIIMIFTTDFVVLLLAWFLFFLWNLLDGVDGNLARYR
                     EQYSKDGSVVDAMAGYVAMVLTYFGAGIVAAHLNDSDIYIILGALSGISLIFPRLVMH
                     KYINTVAQDESVSSIKDKSDFNTIKILALNMTSITGIPQVLLLLTILTNQWVLFTLVY
                     FTINFLLMIFSLYSLFKKENV"
     gene            complement(17784..17960)
                     /locus_tag="VUR43_001723"
     CDS             complement(17784..17960)
                     /locus_tag="VUR43_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HET5413379.1"
                     /translation="MKIQEELKLLKEFIKICSKNKIKYFALGGSLLGAVRHKGFIPWD
                     DDMDLSFPKSSIYV"
     gene            complement(17998..18942)
                     /locus_tag="VUR43_001724"
     CDS             complement(17998..18942)
                     /locus_tag="VUR43_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET5413380.1"
                     /translation="MNIVYATDNNFVDVLSASIKSLYTTNSDLDLNLWIIADKVSDRN
                     KEKINRLSKQFAQREINWIENVEIPFKLHLDRGSISSFSRLFLGSVLPSSMSKVLYLD
                     SDIIVMDSLRSIFDIDFKGKILYGVNDTFNKEYKQVLGIPIDKPMFNAGVMLINLELW
                     RNNNVEERFLQVIQKFNGTILQGDLGVLNAVLYNSFGVLPPEYNYMTIFEDLTYEEMI
                     VFKKPINYYSKEEIKNARERIVLRHFTTSFLSKRPWQEGSNVAHIDQFKKYYEGSYKN
                     VKESILLKIVQKLPKKCSVFLLGIIQSKFRPKLYRILK"
     gene            complement(19038..20405)
                     /locus_tag="VUR43_001725"
     CDS             complement(19038..20405)
                     /locus_tag="VUR43_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET5413381.1"
                     /translation="MNGKIVKSSLAIIQSFLVILLTYLLSAVRETEIVSTTAIALYIL
                     HYFVFYISDYGQDFFKRGYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LTLHALLVYVLNLFIKWYWKRAYPNFKGSKKILLLTATSRVEKVLDRLIESNEVVGEL
                     VAVSVLDKPDFQHDCLKVVAEGEIVNFATHEVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDRSLARNKQIREMAGLNVVTFSTTFYKTSHVIAKRIIDIVGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPE
                     QKRRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVAYINGWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            complement(20420..21109)
                     /locus_tag="VUR43_001726"
     CDS             complement(20420..21109)
                     /locus_tag="VUR43_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HET5413382.1"
                     /translation="MPTLEISQAKLDSVKKAEEYYNALCTNLQLSGDGLKVFSITSVK
                     IGEGKSTTSTNIAWAFARAGYKTLLIDGDIRNSVMLGVFKARDKITGLTEFLSGTTDL
                     SQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIIVDTAPVGVVI
                     DAAIITRKCDASILVTEAGEINRRDIQKAKEQLEHTGKPFLGVVLNKFDTSVDKYGSY
                     GNYGDYGKNKK"
     gene            complement(21119..21811)
                     /locus_tag="VUR43_001727"
     CDS             complement(21119..21811)
                     /locus_tag="VUR43_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HET5413383.1"
                     /translation="MKEQNTIEIDVFQLFKTLWQRKLMILLVALVTSAGAFAYSTFIV
                     KPEYTSTTRIYVVNRNQGDKPGLTNQDLQAGTYLVKDYREIILSQDALEKVATNLKLD
                     MPAKTLASKVQVAVPADTRIVSISVKDKQPEEASRIANSLREVAAEKIVAVTRVSDVT
                     TLEEARPATTPSSPNVRRNSLFGFLGGAVVTVIAVLLIELLDTRVKRPEDIEDVLKIP
                     LLGLVPDFDKMK"
     gene            complement(21820..22551)
                     /gene="cps4B"
                     /locus_tag="VUR43_001728"
     CDS             complement(21820..22551)
                     /gene="cps4B"
                     /locus_tag="VUR43_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4B"
                     /protein_id="HET5413384.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLDKLEKKRIPTLNDS
                     RYALIEFSMNTPYRDIHSALSKILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QVNSSHVLKPKLFGERYKFMKKRAQYFLEQDLVYVIASDMHNLDGRPPHMAEAYDLVT
                     QKYGEAKAQELFIDNPRKIVMDQLI"
     gene            complement(22553..23998)
                     /gene="cps4A"
                     /locus_tag="VUR43_001729"
     CDS             complement(22553..23998)
                     /gene="cps4A"
                     /locus_tag="VUR43_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HET5413385.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VDQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKLIDLLGGIDVYNDQ
                     EFTAHTNGKYYPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIKKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGDYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
BASE COUNT         7403 a         5068 c         3946 g         7820 t
ORIGIN      
        1 atttttctgg gtgattttgt catagcacta ttgtatttat gtgcttaaca aaagcctgag
       61 aagacatctt ctcaggcttt ttctgtacta taaacctcat tggaaaagat agagactgct
      121 tccgtaatct tgttaagagg ttttactaaa tactagtctt tcttcgtttt tactacaaag
      181 agagcagata gggctagact aacacttgct aggaagaggg atgtgtcaga ttgactctca
      241 cctgttgctg gcaagatttg ttcaggtgtt tctggtctag ctatttcttg cttataatct
      301 ggcgtcttac cttgatcgga aactatagag ctaagtttaa actcaggttt ctctacagtt
      361 ggagcatctg gtttcgtagc agaatctttt aattggttga gataatctgc aaagtattcc
      421 accattcttt ccgtcaagag atggttatcc gtcgcatatt tcatgcttgc ctgaacacta
      481 gctacttcct cttgattgtc tttgtctgtt aatttctgag ctttagccaa agctgcttca
      541 tagcctgaca agtcaagagg tgtttctgct acctgtggac gagtaaagat gagttccgct
      601 gcagattggt atttatcgcc accatctccg taagtcttag tacctgtaag gacaattttc
      661 ttagccttaa ttgtcttacc aaaatcaatg tcttttggct tattgttatc tggccaatca
      721 gttgcagtaa aggtatgctc cttgccagac tcatctgtca caacaagttt cacatcacgc
      781 aagttaccat ttgaacctga tccacgtgga acgtaacgaa gtccagtgat ttcagttggt
      841 tctttcaaga ccatggttgc aggcttgcct acatctcctc cgccccatga tgtatgccat
      901 aaactagata agtttccatc aaaggcattt gcaagacctt cttgagcctg agcaggagct
      961 gtaagacttg caaagtcatc tgctaccaaa gccgttttct tctgaaccaa agcattcttc
     1021 aaggcttcaa tcttggcaat ctctgcacgc gcttcttcca cactgatatc atcatcggcc
     1081 tgactgaggt taaagaccgc ctctttcaaa gcatccatag actctttggt gtagttagtc
     1141 atggcaaccg ttggcaagta gttcttcaga gcattttctg tcaacatctt acctgttagg
     1201 gtaatttctt cgatttgaag attatccatc atgaagtcgt tataaccacg gaagttggca
     1261 tttccaccag aatcaccacg agtattactt gcatttccag ttgagtagat acctacccaa
     1321 gtatcccctg tttctgcacc tgtcacgagg aaggttgcct tcttggcttt cttagaatct
     1381 gtccaagtat ttggcaattc atgcatttcc aagttgcttg cttgagtacc acgacgacct
     1441 gactggaatt ttcccttacc gactacaaaa gcataggtat tgtctgaacc tgcttcgtat
     1501 tcaaaggtta cacggtaggt cttacctgct tcaaaacgga agttttgcgg aatagtttgg
     1561 taaaccaagt tacgacggct cactagtcca tttgtcttga gtgaccaatt tccttcgata
     1621 acatcatcga ctttcttacc attccaacca cgttgtgtat atggatcgtg tttttcagac
     1681 aagtgagtgc ggttatcttc gacaccttcg acaccaccca ctacaaatgg gaagataccc
     1741 tgagcaacat tttcaaagtc ttgcttgaag gtgcctttac ctgtatcatg cttgtctcca
     1801 tacatgcttg aattgttttc aaaggtacga atttcatcaa agtaagttgc ttgatcacca
     1861 gcttcacgac tcaatgtcag agtaacattt gagacgtccg atccagttgt aaagaaggcg
     1921 tacatgtttt ggaagtaact tgtatcgtca actgtagcat tgttacgacg tgtattgtgg
     1981 gcgtaggcct ttacatagtt gagggcgaga gacttattgg tataagtagt cacttctttt
     2041 tcaccagtat tcacagtgat acttgccttg gcattactac ggttatcgac accgacataa
     2101 acggcatact tagtatttgg tttcaagcca gttaatttct gagtgagact aactttttct
     2161 ttgtttcctt gaatacgaag catatcgttt gccccttgag acttgacaat ttctgcctta
     2221 gaagcatcac ctgaaatggt ccaatgtttc aaagtaccgc tattaaatcc ttggtcatag
     2281 atgtgcatgc cttcactcca tgacatttca ggattggttt gtttcgaacg atagagaacg
     2341 tatggttgat ttgctagaag atctagggta attttaccat cttttacagc tagttcttgc
     2401 tcttctgtct taccttggtc agttagcttg taaaggtaaa ccttgctctt tgcccaatcg
     2461 cttggaaggg tccaagttgt tgcaccggcc tgcgtattga agtagtacat cttttcctta
     2521 tcagtagaaa gtttcttacc atttgcatcc cagttccaag gagtcaagta agctgaacca
     2581 tcttggatga cacgtccgtt gagagttact gtacgttcgc gatattgtgg actattgaca
     2641 tcatttgact tacgagttac aactacttta ttattgtcag catctaccaa ttccactcgc
     2701 atttctggag tccatttata ggtgctaccg ttatcggtca tagtcaccgg tgtaccattt
     2761 tcccatttac ttacagtgaa gtgttggaag tacttagtca tgacgtcatg ggcaaataag
     2821 ttggttacat agccattgta gtcacttctt ccttgccagc cttcaaagtc tttcatgctg
     2881 tagccaccta gcagtggata gttggctgca ccaccataac ttctgtagtc cccaacccaa
     2941 gcatcttttt ggtggttacg gataaagcgg gtgatggcac tgttgatacc tttattggtg
     3001 tagccaccgt aggtcaagtc agctgcccag tgatggaagg tagagtcgta ctcaccacca
     3061 tggccccact cgatcgcaaa gcgccagcct tgtttgttaa tttctttagc aagaacgtgg
     3121 gtagcccagg caccgttatc acctgattga ccattacccc aaacgtccac atagataaag
     3181 tcgagaccgt caccaagttt tttcttcaaa tcttcccaac gtgccaaacg accatgagct
     3241 aggtcatagg cagcatcaat gttgatacct tgatctagcc agttccaacc atagctatag
     3301 cttccatctg gattcttacg gagaattttt tcattgaagt atttagactc aggataagtt
     3361 tctgaagcgt taacgtggat acctagatga gctccatatt tcttagcctt ctcaattagg
     3421 gtcttgaagt cttcgacacc accgatacgc ttaccaatat cagcatagtt caagtgacca
     3481 gagtcatggc cttcgctacc atatccttta aggagaacac cttgcccaag accatctgtg
     3541 tggagattga ttttcttgat accatccaag gtcataagga atggattttg tgcttgagaa
     3601 ccaaagttca tcgcgatacg gtaagctgtg atatccttaa ctttttccca accttgagga
     3661 ttgttcataa tgctacgata agcaatggca ccatcttgcc aatcaacttt cttgtctgca
     3721 ttggcatctt cagtgataac aaccttagca cttggaagtt ccttcgtgta ttctgggaaa
     3781 acaatgccct tataagcttt ttcccattgc cattcagagc tgtggattcc tacatagttg
     3841 gcatttccga ctgtttcttt ataagctgtc aaacgagtcc agtcattcga accaccacca
     3901 tagctatttt gagagttact ccaaacacca gcagcaagct tatctgtaga aacaaatcca
     3961 tacatgtaac ccttagccaa atccttcatt ggattagtta catcgatatg atcatctccg
     4021 ctgacatgcg tattgtttga catggttgcc ccatcaaact tagcaccagt ttgatcacta
     4081 gaaacagaga ctaaagcatt gccgaggaaa ctaatagaag aaagtagttt tctttcgtca
     4141 tcgatctttt gacctggagt gacttgattg tggttgacaa tcttggtcac atcaaagtgc
     4201 aattgattgt ccacaacttg caagcgtact gtcatttccg cattgattaa gtgagcatca
     4261 tcgcgaagct tcatcaagta ctctgctgtt gtctcattga ttttcttata agtgacttca
     4321 ggggtgattc ggtggttatt gataaagact tggttgaact gttgcacctg tcctggcaaa
     4381 gtatgtccat tcaaggtgta ttccttgaca cgagggaagg cttggtcaat cactgctttg
     4441 aggaccttag actgaatcgt gtcataagtc accttgctat catcaacttc aggacctgtt
     4501 tctttttcag caggggtatc ctctgttttt accccctctt ggttatccgt tttaacgcta
     4561 acaactgttc gctcatcgtc ataagagccc gccttgagaa gaatcttctt ctcattttta
     4621 agatggtcat tgaccgcagc tggtagagtc actgtgtcaa agagattgac atcattattg
     4681 ctggcattta gctgaccgtc tgacttgaga gtgatagaga gacggtttgt tgatcctgtt
     4741 tcaggagcag caacacgact acctctatac caagtgctag ttgttggaga tttatactcc
     4801 cagaaccagc catccttgtc ataaccgaca aaaacattat tcttggtatc tttaaatttc
     4861 aaaaagacac caaagcgtga tttgcccttt tcagaatcat ctttgaaggt taaatcaaca
     4921 gttgcatttc cattggcatc aacggtcaag cccttctttt caaacagggc tggtttgcct
     4981 gcgttatcat tttgagcagt tgaggatagt tggttgtagc ggacaccttt ttcttctcgg
     5041 atagtgactg ttccttgttg ctctttattc gctaccgttt gccattcagg ggttaccgtc
     5101 ttaggtgttt caggtttagc agctgcaggt ttatcctctt ttggtttttc ttcagccggt
     5161 ttttcttttt caagtgctaa tagttcttct tctgtcttag gtccatctgt aacttctgga
     5221 gaaccttggt cttctcccac cttaggcgct tcaaaatcac gcccatcatt ctcttttgct
     5281 gttgcaagag cagtagctaa atcagctggt aagttcgccg tggaaccaga ctgcacgcta
     5341 tctgcaagaa ccggacttgt cccaaagaat gcagctccaa tcataacaga agcaacacct
     5401 aatgaaaatt tccgaatact atatttacaa cgtttttcaa ataatccttt attcataaac
     5461 ttctaaatcc tttcattttt gagcaagcgt ttacattttc tttttaaaaa atactccttc
     5521 ctctgaaagt gcaatgctta accctgataa ataaaaaata attatacttt taatataaca
     5581 aataatagct gagaaagcaa taggaaacaa gtaaaattaa caaaaatttt ctctattctg
     5641 acaaaaagag gctccaactt ttgggggtca gtacatttag aatctttctt tacaaatgta
     5701 aaaaaggatt cagcattcaa gagaaatact aaatcctttc ttatattttg caacagttat
     5761 ttcacatgtt ttgcgagatc ttcttgagcc tttttattag actcttcttt ttctttcatc
     5821 catttttcct gagctttttg gtattcatct acagtgactg ccttgtcttg aagttccaaa
     5881 tatttataca agactggttc acttgtacct ttatttcctg acaatgcaaa tggtattgta
     5941 aatggtacca tcttagacaa gattggacgc cctgtacgag atgtagttgg aataatcaaa
     6001 gcactatctg tcaaccaagc ttgggctgca gcgtatttat catagcgttt agcaacatct
     6061 gtagtctcat caccagcctc agtaaccaat ttttcgtagt catatagacc tactttttta
     6121 gcagctacat tatcttcccc tgagtcaaac cctaaatatg ttttagtact ttctcctaca
     6181 gatggtttga tgatatcaag gtaggttgat ggatcggcaa agtctggacc ccaaccgaca
     6241 ttatctgata aatcccagtc ttcgccagca gcattttcag caaaatatgt aatattgttt
     6301 acttcgtctt tttgtagttg ttgaatatca atgactacat tatccgctcc taaagttgct
     6361 tccaaggatt gtttcataga ttggacgcgc tgaacttttg tagttgctgt ttggtcaact
     6421 ggcatatcca aatgaattgg gaatgtcaca ccttctgctt gtaaggctga tttagcttta
     6481 gcaaattcag ccttggcttt ttctggattg taaagaccat cctgagaatc tgcaagatta
     6541 acatccttcc attcatcccc ataagtaacc aatttctctt tgaccatatc gccaaagttt
     6601 ttaccgtctg cttgaacaaa tgttggtgga acaaagatat tacgtaagat tttgcttgct
     6661 ccagtttgtc cattcaactg agaggcatag gctgtacgat caaaaccaaa ggcaatagcc
     6721 tgacggaaat ccttgtttaa gagagccttt ttagtcgatg ccttttgttc gtcgctggtc
     6781 ttagatgtgt atttatagga ctgacggtca atatttgtac caactagata cgtaatagag
     6841 tcttgttgag tatagacaat attgtcctta atactcttct caagctctgc gaaacttgca
     6901 cttgttggat agagacgagc tgctgtaagg ctaccatctt taaagttttc tgcaggtttg
     6961 ctggtatctt gaccatccca gaatgacaat ttaactttgt caatatgcac attgtcctta
     7021 tcccagtagt tcggattttt cgcaaattca acagaggatt tggtcacaat ggatttcaac
     7081 aaataaggac cgttatacaa gagactactt ggatccgtag ctttggcaaa atcatcccct
     7141 tttgaattca aaaactcttc attaactggc gcaagcacac ccatggttgt cttagaattc
     7201 cagaagcttt ctggtttgtt caaagtgtac tgaactgtct gatcatccag agccttaatt
     7261 cctacttgtg agaaatcttt gatttcccct tttacatagg catccaaccc tttgattgat
     7321 tcttgaacaa ggtaaagagc atctgatttt ttatcagcag catattttag tcctgttaca
     7381 aagtcttgag ctttgactgc cgcgtattct tcaccttcag aagtatacca ttttgcatcc
     7441 ttacggatag tataagtgta agtcaatcca tccttggata cagaccaatc ctcagccata
     7501 gacggcacaa agttcccgta gcgatcattt tctagcaaac catcaaccac gttactggta
     7561 atatttgctg tcgcagcctt agcagttgtc aaatagttga ggttatcagg gtctgtctca
     7621 taaatgtatg agaatgtctt ctcaccttta gtgcttgaac ctgatccaga gcatgcagct
     7681 aaagtagtcg ccgccaataa tgtcacgccc gcaagggcaa atagttttga acttttcatc
     7741 attttctcct ttaaaacttt ctctccatta tagactcttt tcagaaagat gtcaacagaa
     7801 ttttcagaat ttttgaaaat tatttttcaa acaacatctt tgcaaaaaat atgaatatcg
     7861 taaccgtcca ataacgaagt atattgaaaa atctccagac tagagaactc acggatagtt
     7921 cctaatctgg agatttctta tttgcacttt tcttgtacaa ctttagtcca tggtaaataa
     7981 gcctctaaaa cctctttgtt tacgagagtt tcctcgtttg gaagacattc tagaagatag
     8041 aatagatatt tctcgctatt taattgatga cgtttagctg tttccaacaa actcataata
     8101 atagctgttg ctttagctcc ttcaaaactt tgagaaaata accaccctcg ctttttaaaa
     8161 tttagcttag gctaaaagag tccactgaac tcttttactc cgtcccataa ccaatgattt
     8221 aatggcgcgt tcagctagat tattggaaag gaccagatgt ccgtctttca aaatagtctt
     8281 aaaggtttct tcatacttga ggctgtattc aattgccctt cctagttttg aacctgctaa
     8341 aactgactga cgccggcact aagcaaagaa gtcttccatt aagggctgga gatgttcttg
     8401 acgtttctgt agtcgttcat cagctggcaa agcctcccag tctctttcca gggaaaataa
     8461 ctgatcacaa taagctaaac ctttagctcc taaggatgat ttatctgctt gcttgggggt
     8521 cgcttcaaaa aacttccttc tcacatgtgc ccaacatcca acaagttcag cttcttccag
     8581 ttgacgataa gcttctagcg gttcgcagtt taccaagctt agcgtcgcct tgcttctaaa
     8641 ccttggactg ctatcgcata ggcagaacta gaggactaaa gtcctaagtt actgccgcaa
     8701 catatcacaa tgcacatagc cagaataatc tcctaggaat tcttgtacta ctaaaccact
     8761 ccgacgctga tcatgatggt acagcgtgat tgcttgattc tcagctttcc cagacaaaaa
     8821 ggtccaatag taggtcagat ggctatcact ctctagcacc cgataagagg tctcatccgc
     8881 atgaagaaga ggttgttcta acaacttttc tcgtaaaagg ttataaaggg actctaaata
     8941 gtattgactt gccttgatat gccaattaga gatttcctta cgtgtgattg gtaaacccat
     9001 cctagcccaa tcttcttctt ggcgataatt gggtaccttc agattaaact tctgatggat
     9061 ggtgtgagcg ataatagaaa ctgagccaaa gctatgcgcc aaagagacca gcaccaacaa
     9121 caagataatc gtacatctta agctcctttg gagttcattc tctgcctctt ttattagact
     9181 agaaaatcat tctactactt atctcacttc ttgtttgtaa aattcttgca atgcatcttg
     9241 ccaagttgga ataacaaatc cagtagcttt ggctttggcc aggctcatcg ttgagtttag
     9301 cggacgttta gctttggctg gaaattgact ggaatctact ggcttgactt cgacatctgt
     9361 atctttcaaa atttcaactg caaaatcata ccatgttgtg tcttctgtcg catcatttga
     9421 caaatgataa taaccaaatt ccttacgatt ttcagctagg taggtcatga actcagccaa
     9481 ggtacgagtc caagtcggac gaccgtactg gtcatttaca actgttaaag tcttatgagt
     9541 tttcgcaaga ttttgcatgg taaaaacgaa gtttttgcca taatttccaa atacccaggc
     9601 agtacggata atatagaaat tagacacatg cttctcaact aactcttccc ccatacgctt
     9661 agtacggcca tattctgtct gtggatctgg tcggtcatca acttcccact cttgtccaac
     9721 tggtttctta ccatcaaaga catagtccgt agaaatataa actagagttg caccatgctt
     9781 ttcagatgct tttgcgacat tttttgtccc cgtcacattg atggcgaagt ccaactctct
     9841 tccttcatcc tctgctgcat caacagcggt gtaggctgca cagtggtaga ctaaagtcgg
     9901 tttcacctct tcaaaaactt tctcaaccat ttctgcatcg gtaatgtcca tctcagccac
     9961 atctactgcc acgtattctt cattacgttc atccaataaa tagcgaagtt ccgttcctaa
    10021 ttggccattt gcccctgtaa ttaaaatcat ctctagacct ttctaatatg taactcttcc
    10081 caatatagca ataaaaagca gctatttcct gctttttata ctgtaataat ctcctgagtc
    10141 ttagcataat tggcttcaac agcttctttt tctgctttcc accattcttg gttatctgta
    10201 taccacttga ttgttgcctt gagcccagct tcaaagttgg taaattcagg tttccacccc
    10261 aactcatcac ggagcttgct agcatcaatc gcatagcgaa ggtcatgtcc tgcacggtca
    10321 gtcacatgat cataggcatc cacagcttgt cccatttcct taaggataag ttccaaaact
    10381 tccttattgt tcttctcacc atcagcccca atcaagtagg tttcaccgat ttgccctttt
    10441 gtcaagattg tccaaactcc tgaagaatgg tcattggtat gaatccagtc acgaacattc
    10501 ttaccttcac cataaagttt tggcttaatt ccacttagga tgttagtaat ctgacgtggg
    10561 atgaattttt cgatatgttg ataaggaccg tagttatttg aacagttgga aatcgttgcc
    10621 ttgactccaa aagaacgcac ccaggctttg acaatcaaat ctgaggctgc cttggttgat
    10681 gagtacggag agcttgggtt gtattttgtt tcagcagtaa atttctcacc tggtccttca
    10741 ccatgacctg gcaaatcttc gcgtaaaggg agatccccat aaacttcatc tgtcgataca
    10801 tggtggaagc gaatatcata cttacgagca gcttctaaaa gagtataggt tccgatgaag
    10861 ttagtatgaa taaatggcga tggatcattg agcgaattat cattgtggct ttccgctgca
    10921 taatgaacga tagcatctgc ttgagcagcc aacttgtcta ccaactccgc atcagcaatg
    10981 tcaccaacaa ctaactcaac acgattacct aaaatttcct caatattcgc gcggtttcca
    11041 gcataagtca acttatctag gactgtcaca tgaacatctg gaaagttctc gtaaacataa
    11101 tggacaaagt tagaaccgat aaagccagct ccacctgtca cgataatatt tttgtattca
    11161 gtcatattct ttccttttta caaatcttct tttttcaaag gttttacatc cttaagtagt
    11221 ggatgatttt tatctgcttc tgaaacctct gcttctgcaa tattttccca ttcaatacca
    11281 aggcttggat cagcgtagtt cacaaaggca tacttgggtt tgagttcaag agcccagtaa
    11341 tcattgacca gatagctata tgacactgta tctgataaaa cttggaagcc attagctacg
    11401 cctcgaggaa caaagattcc cttactcgca tcaatcactg tctgataggt attcccaaag
    11461 gtttcaccct cgcgtagatc aacccaagaa cccagaactt tccctccatc tgctacagag
    11521 atgtacttat cccaaggctc tgcgtggagg cctcgaagga catttttacg tgagaaggat
    11581 acattgtttt gcaattttcc ttctgcaaag aaagactctg gaaatccaag tggaagcatt
    11641 ttttcctttt ggaaattttc tttaaaccag ccacgattat ctccatgaac ggggatatca
    11701 aactccaaca tgcctggaat agcttcaacc ttgcgtgccg caagcgtctt accgaaaaaa
    11761 ttatctgtca tctatgcttc tccaatcaaa cggagcagat actgtccgta ttcatttttc
    11821 ttaagtgatt gggctaaggc caatacatct tctcgactga tatagcccat acggtaagca
    11881 atttcttcta agtttgctac ctgaacattt tgcatccgtt ggactgtttc gatgtactgc
    11941 gaagcctcta gtaaactttc atgagtgcca gtatccaacc aagcaaaacc acgtcccatg
    12001 agctcaacag acaaatcacc acgatccaag taagccttgt tgacatctgt aatttccaat
    12061 tcaccacgag gacttggttt aatacttttg gcaatctcta ctacatcatt atcatagaaa
    12121 tagagtcctg tcactgcata gtttgaacga gggtattctg gcttttcttc gatggagata
    12181 gcattcatat tttcatcaaa ttctacaaca ccaaagcgtt ctggatcctt gacatggtag
    12241 ccaaaaacag tcgcaccttt ctctttcttg gctgcttttt gaagcatttt gctcaaacca
    12301 gggccgtgat agatattgtc ccccaagatc aaagcaacac tatcatcacc aataaactct
    12361 tccccaatga taaaggcttg tgccaaacca tctggacttg gttgctctgc ataagaaagt
    12421 ttaatcccaa actcagatcc gtcttgaaga agctctttaa aacgaggcaa atcttgagga
    12481 gttgagatta tcaaaatatc cctaatccca gccaacatca atgttgaaag tggatagtaa
    12541 atcatgggtt tatcataaac cggcataagt tgttttgatg cagcccgagt caaaggatat
    12601 aatcgtgtcc ccgaaccacc tgcaagaata atacctttca ttagtaggat ccctttctta
    12661 tattcactga aattcagaat tagaccttta tcgcaattta taaaaacaaa atgtcaataa
    12721 attttgctaa tttttaatta atcaaagttg atattctaat ttaactgata ggctaggtta
    12781 agtctaataa aataattctt acttaaagat atattatttt aaaaataaac ttccttgaaa
    12841 aatgaacaat ctgattttct agcattatca ttcctattag aatttagaat tgttgacaaa
    12901 atccattatt ttatatttaa aaaaacgtct ttaaaattga taaattattt cgtaacctgt
    12961 tcccactaat agcaatgttc cagaaactat tcttatttta aattaattta tcacctgata
    13021 cattcaaatc gcttataaat atgtgtaaaa aatagtatca tattttttat cattttctat
    13081 taaacgacaa aaaggtaaaa atagaatttg ccatctaact gatatatagt tctttttatt
    13141 caaatatttt ctttctaaaa tattctatat acatttttgt atctttacgc tttagataca
    13201 agtataaagt atacgctaac aaataaacta ttactgcgag ccaaatcggt aagtaccaac
    13261 ttgaagaaat aaatataatt gtcataagta attctaacac aatgtcttgc tcaactgata
    13321 tatcaagttt tttagataga attagttctg ctattatact acgtaaagct agcaaaacaa
    13381 ctatagatat aaccgttagc tctaaattat ttaataatag agtagttatt agggtaacta
    13441 acatactgaa caacataatc aaagtattta ttttgagaat atctctttcc atccttagcg
    13501 cctttaaata tgtattaatc accaaggcca tcttcccttc ataaattgac ataggaaaaa
    13561 taagagccat aaaaatcaac gcatcccgat aagctggcaa ccaaagatct agaataattt
    13621 ttaaaggata ataaaagagt aatattgcaa acatgatcag catcaaaaca tttcttaagt
    13681 tggaataaat tttagataaa ttttccgttt ttgtccgttt taacaaagga aagacaacta
    13741 aaccaatcgc attaataaaa gtcattaata aattagagat gcttagcgtc agtgatactt
    13801 tcccgaatgt ttcgatattc caattccatt gaattcccat tcgaacaata ccaataatca
    13861 tactacttgc aatattggat aacattaaat tgattccaac acggatattg tcaaaagatt
    13921 ctctcagatc caatatgaac tcggataagg attgaaaaac aatatcttta caaatccaaa
    13981 aagaaagtag gagagaaaat gtccttccta aaacatccgc ccaaatcatt accttgtatt
    14041 catgccattt aaatataata aacagaaata aaagaaaaat atatatgacg cgatcactta
    14101 tcagaattat agagctatcc tttaatcgat ttgtcatctg caaaatataa acgaataaca
    14161 ttcttaaatt tgtaactatc atactaataa tagtcatgtt ataaatatat tttgcatttg
    14221 gatctgtcac aatcaataag ttaaaaccaa ataatagaaa agaaattaaa attaaaaaac
    14281 tgaaaaattg aagtatttga gaataaaact gtttcttatc taaattctgg tactctaatc
    14341 caccatattt aagataaatt ccatcaatcc aacccagatg aaaaaaacca atatatgtta
    14401 ggtaaaaaat atatagttgc caataactat actcagttac tcccataatt tttggtaaaa
    14461 ttagtacaac tataaccgat gtgacaattg taatcagatt agataaaaag acatgaaaca
    14521 aatttgttat aagaaacttc aatttcatag ctatactccc cacctaaaaa ttgtttcaga
    14581 agatttgtac ttcccattca agactctctt cctccaatta aaatacctac caaatatatc
    14641 cctttatatg actcaataca ttagcgctaa attcatctat ttatcgttaa tttacctttg
    14701 ttaaagtcaa cctgaacttt cagaagaacc caaaagacca gataaaagat aacaatttgt
    14761 attccatatc caatggtaac cattgaaata taaaacacat cctcgatacc atttaaaaat
    14821 attggataaa atgaagctgc taataggatc aacctaaatc tttgaacatt tgtaactaaa
    14881 gaataatgtc taactttttc ataacctaaa gtatataacc acgctgtaaa actctgacaa
    14941 attacaatac caattacacc aaagtctgaa taataacgtc taattgcagt atacacattc
    15001 cctaaagaat aataattagg agacactctc cattctaagc cttttataat attattgtca
    15061 aatcctaatt ttgcaagcat ctcataaatt cccgaaaaag tttctgcacc tagttctttg
    15121 ttacgtcgta tcggatctat aacaaataaa tcaaatagtt gaattgaacc tcccatataa
    15181 cgagtgatgt aactgataaa atcttcctga gaggagcgcc ctaatacaaa ttttaaaaga
    15241 aagaataaaa ctatcaaaat aagaaatgta aacagagagc gagtgatcat tttaaaactt
    15301 ttggtaagtt gagatttagg actcccgtac acagagtata tatacaatat caacagagct
    15361 ccaacaacta accttataag gggcaatcta ccaccactaa tgattgcata gacaaagaat
    15421 atagctattg gaatcaaata aatgaaattt ttctttattt gtttagttat aaaataatta
    15481 ttcataaata tatataaaga aataagtgta gtcgctggaa taattttaga tagttgatta
    15541 atcattccac ttacacgatt ttctacttca tttgaataat aagataggta cctatagtta
    15601 cttatcaaat ctgtaatatt agaaaaactt ctacctgaaa acaatactac tttctgaatt
    15661 tcacggatat aaagaaataa cataacaaga tttagagtca gaagaatgac atagattatc
    15721 tttgaaggat ttatttcttt caattcttca tgcgaaattc cctccacttt aggcctgtac
    15781 gacaattttg tcaacaagga aactataaca aatgtaacaa cccctaacaa tatcaaataa
    15841 aaggttttga aatggagttc tgttccccaa acatttctat taactagagc acttgcaatc
    15901 gaaataaaat aagcgattgt taaaattact gcaggttgaa aaaaatcccc ctcaaataat
    15961 ataaatgtaa taataattaa tagaaaaata gatatgaata agaaatttaa aagcattata
    16021 agagttcttt cataatatat tttttatagg tcccaaaaag catgatggta tataagccga
    16081 ttgttcttac gagttgcttt cgagaaattc gattctgata gaaatatctc acacctttta
    16141 atcctccaat tttgattact tcctgaattt caagtagtct atcacttaaa ggattttttc
    16201 cagaagcttt ttttagcata taaagagttt gattatatac cccagcatgt gtaagtgcca
    16261 attcattgaa acccaatata gcctttctga aaacatttag cggagataat ttaaaatgat
    16321 gactagttgt tacattatgt ccatgtcttc gatacaagac cagttgctca gggcagaaca
    16381 acaccttccc atactctagt gcaaactttg caaaataatt atcatgagac agtttttcta
    16441 tatataaata atctttatca atatcaactg aaggaaccat ctctagcaat gcatgattaa
    16501 aacctgcagt acacccccag atataggcat gaataaaata caaattattt atgttcggta
    16561 attcaatccc cattatttta tttatactaa tatctatcaa attattactg gcatcaatcg
    16621 ttgacatatc agagtaaacc atctctggca tgtcatcttt agaaaatctt aacagctgta
    16681 tttctaactt gtgctctttc caaatatcat cttgatcaca aaaaaagtaa taatcaaatt
    16741 gataattgtt tttaacgtat tcaattagat taaaaaaatt gtaataagct ccatgaaact
    16801 ttgagggatt ttcaacgaat ctaattctat catctatctt agaatacctc tgtattactt
    16861 ctattgtttt atcttttgat ccatcatccc taataaaaag cgtccaatta gtgaatgttt
    16921 gagacctaat actatcaatc tgttgtgaca aatatcgctc accattatag gtggtcatta
    16981 aaattgcaac tgactttccc atttctaaac attctccttt ttgaataatg aatacaaaga
    17041 aaatatcatt aataaaaaat taatcgtaaa atatactaaa gtaaaaagta cccactgatt
    17101 tgttaaaata gttaatagca gtaaaacctg cggaattcct gtaattgatg tcatgtttag
    17161 agccagtatt tttatagtat taaaatcaga tttatcttta atgctactca cagactcatc
    17221 ttgagctact gtattgatat acttatgcat cactaacctt ggaaaaatca atgaaatccc
    17281 agataatgca cccaaaatta tatagatatc tgagtcgttt aaatgagcag ctactattcc
    17341 tgcaccgaaa tacgtcaaca ccatggctac atagccagcc attgcatcta ctacacttcc
    17401 atccttcgag tattgctccc gatatctggc taagttccca tctactccat ctagtaagtt
    17461 ccataaaaaa aatagaaacc atgccagtaa taatacaacg aaatcagttg taaatatcat
    17521 tattataaat ccaacaatca aaggaattat agataaataa gatatttgat tgggagtaat
    17581 atttgttttc acgaaaggaa ctgttaaaag ataggataaa ggtcttccaa cataaaatgc
    17641 aaaatagtcg tttttagcca ttgctttttt agcaggcgac atagtttttc tttcaatatc
    17701 tttacagatt ctatatattg acatctatac tttctcctaa actcattaat acattctcta
    17761 attctaacac tttttccttt atttcaaaca tagattgaac tctttggaaa gcttagatcc
    17821 atatcatcat cccaaggaat gaaacctttg tgtcttacag ctcctaatag actacctcca
    17881 agagcaaaat acttaatttt atttttagaa catattttta taaactcttt taataatttc
    17941 aattcttctt gaattttcaa taaaattctt tcttttttgt cattaatact atccacctta
    18001 tttcaaaatt ctatacaatt taggtctaaa ttttgattga ataattccta ataaaaaaac
    18061 tgaacatttt ttgggtaatt tttgaactat ttttagtaaa atagattctt taacattttt
    18121 ataactacct tcatagtatt ttttaaattg gtctatatgt gcaacattac tgccttcttg
    18181 ccaaggtctt tttgataaaa aactagttgt gaaatgtcgt aagactatac gttctctggc
    18241 atttttaatt tcctcttttg aataataatt aattggtttt ttaaaaacta tcatttcttc
    18301 ataagtcaaa tcttcaaata tggtcatata attatattct ggaggaagta caccaaatga
    18361 gttatataaa actgcattta aaacccctaa atctccttgt aatatagtac cattaaactt
    18421 ttgaattact tgcaaaaatc tttcttcgac gttattattt ctccataact ctaaattaat
    18481 aagcataact ccagcattaa acattggctt gtcaattggt atacccaaca cctgcttgta
    18541 ttctttatta aaagtatcat tcaccccata gagaatttta cccttaaaat caatatcaaa
    18601 aatacttcgt aaagaatcca taacaataat atcactgtca agataaagaa ctttactcat
    18661 tgaagatgga agaacacttc ccagaaataa tctgctaaat gaactaattg atcccctatc
    18721 taaatgtaat ttaaatggga tctcaacgtt ctctatccaa ttaatttctc tctgcgcaaa
    18781 ttgttttgat aatctattta tcttttcttt atttctatcc gaaactttat cagcaataat
    18841 ccataaattt aaatccaaat ctgaattagt agtgtaaagt gatttgatgg aagcactcaa
    18901 tacatctaca aaattattat ctgtggcata aactatattc ataaaattcc tacttctaaa
    18961 tttattttca cttataaaaa agattgagtg agatatattc gaaactttta cctctacaaa
    19021 tatcctacac aaccaaacta tttcgctcca tctctcataa atacaacttt aaccgttttc
    19081 aataaaattt caatatcttt ccagattgtc caaccattaa tataggccac atctaatttg
    19141 acaacttcat cgaaattctt gatttcactt cgtccgctga cctgccataa acctgttatg
    19201 ccaggtttaa aacttagtcg gcgtttttgt tctggggtat agtgctcata ctcgtccact
    19261 gttggtggtc gtgtacctac caagctcata tctcccttta gaacattgta aaactgtggt
    19321 agctcgtcca agctagtctt ccgtataaaa cgaccaattt tcgtgatacg aggatcatcg
    19381 tccaccttaa acattccacc ctgcatggta ttttgttcca tgagttctct ttttttcgcc
    19441 tcggcatcta cacacataga gcgaaactta taaaaagtga actgacgacc attttttcct
    19501 atacgcgtct gagcaaaaat agcagagccc ccatcctttc gaatcaaagg aaccagtaca
    19561 atactgacta aaccacatag tatcagccct accaatgcac ccacgatatc aataatccgc
    19621 ttagcaatta catgactagt cttataaaat gttgtagaaa aagtcacaac gtttaatcct
    19681 gccatctcac gaatttgctt gttacgtgcc aaactacgat caaaagcatt tagattgact
    19741 gttacatcaa ttcccatcgt ttcaaactga gagacaagct ctccaatatt gtatttttca
    19801 cttggaagat tgataaagac ttcatcgacc acctcatgag tcgcaaagtt tactatctcc
    19861 ccctctgcta ctacctttaa acaatcatgc tgaaaatctg gtttatctaa gacactgacg
    19921 gctaccaact ccccaacaac ctcatttgat tctattaatc tatccagtac cttttcgaca
    19981 cgagaagttg ctgtaagtag gagaatcttc ttacttcctt taaagttggg ataagcccgc
    20041 ttccaatacc acttgataaa taggtttagc acatagacta agagagcatg taatgtgagg
    20101 aagtaaatca tgcctcgtct ggaaatacta aatcgatcct ctaagaaaaa attagaaata
    20161 ctaatcgcta gtgcaaagaa taggatatat ttcaatgtct ggacaagttc aatcaaatat
    20221 ccccttttaa agaaatcctg tccataatca ctgatataaa agacaaaata atggaggata
    20281 taaagtgcaa tagctgttgt tgaaacaatc tccgtttctc tcacagcact aagtagataa
    20341 gtcaataaaa taacaagaaa gctctggatt atggccaatg aagactttac tatttttcca
    20401 ttcatctcta tcccccgacc tattttttat ttttcccgta atctccataa tttccataag
    20461 aaccgtattt gtctactgaa gtatcgaatt tattcaacac aactcccaaa aacggcttcc
    20521 ctgtgtgttc caactgttct tttgcttttt gaatatcccg tcgatttatt tcacctgcct
    20581 ccgtcactaa aatagaagca tcgcattttc gcgtaataat agccgcatca atcacgacac
    20641 cgacaggagc agtatctaca atgatgtagt caaaatattt acgcaaggtt tcaagcattg
    20701 tactgaaatt cttactttga agaagagctg tcggattcgg tgacacagag ccagcctgaa
    20761 ttacaaagag attttcgata ttggtatcac aaagcccttg tgataggtct gtagttcctg
    20821 ataaaaattc tgtcaggcct gtaatcttat cccttgcttt aaagacacct aacataacag
    20881 aattgcgaat atctccatca atcagcaacg ttttgtaacc tgcacgcgca aaagcccaag
    20941 cgatattggt ggaagtcgtt gattttcctt ctcctatttt cacagaagtg atagaaaata
    21001 ctttcaaacc atctccactt aactgtaggt tcgtgcacaa agcgttataa tattcctctg
    21061 ccttttttac agaatccaat tttgcctgtg agatttctaa tgttggcata acttcctcct
    21121 atttcatttt gtcaaaatct ggaacgagcc ctaaaagtgg aattttcagt acatcttcaa
    21181 tatcttcagg acgtttcaca cgggtgtcga gcaactcaat caaaagaaca gcaattactg
    21241 ttacgactgc tcctccaaga aaaccaaaca aggaattgcg tcgaacattt ggagaagagg
    21301 gagtcgtagc tggtcgcgct tcttcaagtg tcgttacatc agatactcgc gttacagcga
    21361 cgatcttttc tgcagcaact tctcgtagag aattagcgat acgactggct tcctctggct
    21421 gtttatcctt gacagagatt gagacgatac gagtgtcagc tggtacagcc acttgaactt
    21481 tgctggctaa cgtttttgct ggcatatcca acttcaaatt tgtcgctact ttttccaatg
    21541 catcctgcga aaggataatc tcacggtagt cttttaccag ataagttcct gcctgcaaat
    21601 cctgatttgt cagccccggc ttgtctcctt gattgcgatt cactacgtaa attcgcgtgg
    21661 tactcgtata ttctggctta acaataaaag tgctatatgc aaaagccccc gcacttgtca
    21721 caagtgccac taataaaatc attagcttgc gttgccacaa ggttttaaat aattgaaata
    21781 catcgatttc tatcgtgttt tgttctttca tcatttctcc taaattagtt gatccattac
    21841 aatttttcga ggattgtcta taaaaagttc ctgagccttc gcttctccgt atttttgggt
    21901 aacaaggtca tatgcttctg ccatatgagg aggtctaccg tctagattgt gcatatcact
    21961 tgcaatgaca taaaccaaat cctgctctaa aaaatactga gctctttttt tcatgaattt
    22021 ataacgttcg ccaaaaagtt tgggtttgag gacatgtgaa ctatttactt gcgtgtaaca
    22081 gcccatatcg attagttctc gaacgcgttt ttcattattt tcaagagcat catagcgctc
    22141 aatgtgggca atgactggag taattcccaa catcaagatc ttgctcaagg cgctatgaat
    22201 atcgcgataa ggagtgttca tactaaactc tatcaaggca taacgactat cattgagggt
    22261 cggaatccgc tttttttcca gcttatccag aacatctggt gtgtagtaaa tttcagcccc
    22321 gtaagcaatg actaagtcac tcgccacttc cttagctatt tcccgaacct gaagaaagtt
    22381 ttctgctatc ttctcttccg gagtttcaaa catgcccttg cgacggtgag aggtagagac
    22441 aatggttcgc accccctgtc tgtaggcttc tgccaagaga gccttgcttt cctctcttga
    22501 cttgggaccg tcatctacat caaaaacgat atgcgaatgg atgtctatca tttcatctac
    22561 cctccatcac atcctgtata gctgctttaa ctacagctaa actactatca tctatttcca
    22621 tcacatagag gttactgtct ggcattgcat aagaaggaag atccatccga cctgtccctt
    22681 ttaaatcttg agaatttact ttataatccc ccccactttc caactgagta ttcactaaat
    22741 ctatcatagt ctcaatcggc atatttgttt gaagagaatc ctgcaatcct tgaagaatac
    22801 tactatagtt tttcaaaacc tctgtagaag ttaacttctt aataattgct acaatgacct
    22861 tttgttggtt gcgaccacgg tcacgatcgc catctgctag tgagtagcgc tcacgaacaa
    22921 aaccgagagc ctgttctgaa tcaagatgaa cattgcctac agggtaatac tttccattcg
    22981 tatgggcagt aaattcttga tcattataaa catcaattcc acccaacaaa tcaatcaatt
    23041 tcaaaaacga agtgaagttc aatcgcacat agtaattgat atccactcca tagagatttt
    23101 ctaaggtgtg aatggacgaa tcaactccat aaatgcccgc atgggttaat ttatcttttt
    23161 gattatttcc accatctgcg attggtacat aggcatcacg tggtgttgtg gtcaagagga
    23221 ttttcttggt atctcgattg acagtcatca ggatattgac atctgatcgc gacaccgaac
    23281 taataggacc ataggtgtca attccactaa catagatatt gaaagactga ttcttagacg
    23341 tcttaggagc ttctactttt ttagtgaatc ccttggtata aatctttttt atcttcgatg
    23401 catagtctgg atactctgac tcgatgatat tttcaaagac actatttaag acaatggcct
    23461 tagtctcccc tgcaatcaaa ctcttgtaag ctgccaagta agacgaactc tggtcgaccg
    23521 tcaaatcggt attctgactt gacttgatat cagctagtag tttttgaata ttttcattat
    23581 cagtcccagt cggtgctgtc acactcgtca gttgcgtaac attttcgatc tcactatctg
    23641 ctaaaacagc gacactgatt gaatattctg agtaattaga agtcgcattt aaacgattgg
    23701 tcagtccaac aaactgctgt actgcaaaga gcgacacaga gctgacaagg atagagaaca
    23761 ccaacagaaa aatagtaaat ttttcagctt ttttatagat aatcaggagt agccctacca
    23821 aggcaactag taggactaac gcagttacca ctagattaag atatctaaaa gcaaggatat
    23881 tgtacttaaa gattaagaac aataaaaaac aaactaacaa taaataaata gtcaacaaaa
    23941 ctatattaac acttcgcttc actttctgtg aacctgattt tttaaaacgt ctactcatga
    24001 ttaacaccta tacattgaac atcatacaat tgtatcactt ttttacggta atgtctacac
    24061 cttttttcac tatctgcatc tttaagtatc ttagtagact tcccgcgaaa caaaaatata
    24121 gtaaaatgaa ataagaacat gacaaatcaa tcaggacagt caaatcgatt tctaacaatg
    24181 ttttagaagc agaggtgtac tattctagtt tcaatctaat tatgaacaag acccaga
//
LOCUS       DAVDHC010000032        23477 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVDHC010000032 DAVDHC010000000
VERSION     DAVDHC010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23477
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.032"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(21..2180)
                     /locus_tag="VUR43_001730"
     CDS             complement(21..2180)
                     /locus_tag="VUR43_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET5413386.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(2177..2773)
                     /gene="recU"
                     /locus_tag="VUR43_001731"
     CDS             complement(2177..2773)
                     /gene="recU"
                     /locus_tag="VUR43_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET5413387.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            2839..3366
                     /locus_tag="VUR43_001732"
     CDS             2839..3366
                     /locus_tag="VUR43_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET5413388.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            3436..3765
                     /gene="gpsB"
                     /locus_tag="VUR43_001733"
     CDS             3436..3765
                     /gene="gpsB"
                     /locus_tag="VUR43_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET5413389.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            3786..4166
                     /gene="rnpB"
                     /locus_tag="VUR43_001734"
     ncRNA           3786..4166
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VUR43_001734"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4251..5408
                     /locus_tag="VUR43_001735"
     CDS             4251..5408
                     /locus_tag="VUR43_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET5413390.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            5421..6815
                     /gene="mapZ"
                     /locus_tag="VUR43_001736"
     CDS             5421..6815
                     /gene="mapZ"
                     /locus_tag="VUR43_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET5413391.1"
                     /translation="MSKKRRNRQKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            6891..8315
                     /gene="gndA"
                     /locus_tag="VUR43_001737"
     CDS             6891..8315
                     /gene="gndA"
                     /locus_tag="VUR43_001737"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET5413392.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFSFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            8327..9016
                     /locus_tag="VUR43_001738"
     CDS             8327..9016
                     /locus_tag="VUR43_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5413393.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            9115..10134
                     /gene="cbpC"
                     /locus_tag="VUR43_001739"
     CDS             9115..10134
                     /gene="cbpC"
                     /locus_tag="VUR43_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET5413394.1"
                     /translation="MKLLKKMMPIALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGLTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGTLAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(10252..11484)
                     /locus_tag="VUR43_001740"
     CDS             complement(10252..11484)
                     /locus_tag="VUR43_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5413395.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMISSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFITSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(11527..12352)
                     /locus_tag="VUR43_001741"
                     /pseudo
     CDS             complement(11527..12352)
                     /locus_tag="VUR43_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
     gene            13015..13344
                     /locus_tag="VUR43_001742"
     CDS             13015..13344
                     /locus_tag="VUR43_001742"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5413396.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMPPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            13466..14344
                     /gene="mvk"
                     /locus_tag="VUR43_001743"
     CDS             13466..14344
                     /gene="mvk"
                     /locus_tag="VUR43_001743"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET5413397.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            14326..15279
                     /gene="mvaD"
                     /locus_tag="VUR43_001744"
     CDS             14326..15279
                     /gene="mvaD"
                     /locus_tag="VUR43_001744"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET5413398.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            15266..16273
                     /locus_tag="VUR43_001745"
     CDS             15266..16273
                     /locus_tag="VUR43_001745"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET5413399.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIVFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            16257..17267
                     /locus_tag="VUR43_001746"
     CDS             16257..17267
                     /locus_tag="VUR43_001746"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET5413400.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAETCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEANDQMK
                     KA"
     gene            17345..18043
                     /locus_tag="VUR43_001747"
     CDS             17345..18043
                     /locus_tag="VUR43_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET5413401.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KIVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            18040..19035
                     /locus_tag="VUR43_001748"
     CDS             18040..19035
                     /locus_tag="VUR43_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET5413402.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENQSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            19049..19681
                     /locus_tag="VUR43_001749"
     CDS             19049..19681
                     /locus_tag="VUR43_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5413403.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            19682..19923
                     /locus_tag="VUR43_001750"
                     /pseudo
     CDS             19682..19923
                     /locus_tag="VUR43_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            19845..20159
                     /locus_tag="VUR43_001751"
     CDS             19845..20159
                     /locus_tag="VUR43_001751"
                     /inference="COORDINATES: protein motif:HMM:NF020296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET5413404.1"
                     /translation="MIDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQL
                     VVTKSWWDTVDILDRVVGSLVYKHPELEEIILIFFENLFKPRQLYLQPQNSVLSNLWL
                     AS"
     gene            20178..20450
                     /locus_tag="VUR43_001752"
     CDS             20178..20450
                     /locus_tag="VUR43_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET5413405.1"
                     /translation="MSIKWSLSDNIWLRRVAIDHQLLRKEKTNTQLMEKILLHNLNQT
                     EFFINKAIGWTLRDYSKTNPTWVTCFIEKNKERMAELSIKEASKYL"
     gene            20600..20839
                     /locus_tag="VUR43_001753"
     CDS             20600..20839
                     /locus_tag="VUR43_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413406.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            20920..21741
                     /gene="cbpG"
                     /locus_tag="VUR43_001754"
     CDS             20920..21741
                     /gene="cbpG"
                     /locus_tag="VUR43_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HET5413407.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYYYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGNWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            21760..22782
                     /gene="cbpF"
                     /locus_tag="VUR43_001755"
     CDS             21760..22782
                     /gene="cbpF"
                     /locus_tag="VUR43_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
                     /protein_id="HET5413408.1"
                     /translation="MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYY
                     KKGALKETYWRVIDGKYYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWF
                     YFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
                     YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPATGI
                     MQTGWQYLGNKWYYLHSSGAMATGWYKEGSTWYYLDAENGDMRTGWQNLGNKWYYLRS
                     SGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNY
                     NGEWVK"
     gene            complement(22910..23477)
                     /locus_tag="VUR43_001756"
                     /pseudo
     CDS             complement(22910..23477)
                     /locus_tag="VUR43_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         7048 a         4119 c         5371 g         6939 t
ORIGIN      
        1 aaaaatctgg gtgataaatg ttatggttgt gctggttgag gattctgatt ttgttgatca
       61 ggggttgtat ttgattgttg cgtattattg ttaggattgg tagtcgtact attatttgtg
      121 cttggagtgg ttgagctaga ctgtgaagtt gaactatctg atgatgagct tgaactttca
      181 gttgatgggg gttgttgtgg agcaggtgag ttccacgtag aacgagcacc atttttaaat
      241 acgaattctc catttctgta gagcccctct ggtatattcc aatcttctgg attgcttcct
      301 tcagacaggt aggtcatcat agagcggtaa actttggcag cgaccgtaag gccattgcct
      361 acaagtggtg tcagacggtt agaatagcct gtccatacag ccattgaata tttacgcgta
      421 tagccagcaa atagttcatc aggtgctaca aattgagagg tcttgatgtg gttttcaatt
      481 tcctcgtctg tatagttaga ggttcctgtt ttaccagcct gagggagcca agcaagatag
      541 gcatttcgtc cagttccata agtcaagact gttttcatca tgtcggtcat catataggct
      601 gtcgtttctt tcatggcacg agttccgaca ttagagaact ctttttcact cccatcacta
      661 aagacgactt tatggatata cattggttta tagtaagttc caccatttgc aaaggcagcg
      721 taagcagcag ccatcttttc actacttgct ccatattttt tgtctgattc ggttgtgtta
      781 cttgaaatgg catttgagta gtgaatactt gggtagtcga ttccgagacc atttaggaaa
      841 gtcttggcgc ggttgagtcc gaccttgttt agagtttcca cggctgggac gtttcgcgat
      901 tgttgcaggg cgtattgcaa ggtgatgttg ccaaagtagc ccctatccca gttataaaca
      961 ggagtatttg tcccagggta attatagggc tcatcgtgaa cgatagtagc agttgaatcg
     1021 tagacaccgt actccaaggc aggagcatag tctgtgatcg gtttcatagt tgatccccag
     1081 tcgcggtttg tttctactgc ttggttaatt ccgaaggaaa cattacttga ctgatggcgt
     1141 gctcctagct gggcaatgac tttaccgtta gaaacatcaa caatggtaga agcgacttgc
     1201 aattcatcgt ctggataggc aacgtattcg tctgtattgt aaatatccca cagatgtttt
     1261 tgagcttctt ggtctacatt tgtgtagaca tccatcccag ttgtgagcag gttatagcct
     1321 gtttcttctt caacttgatt gatgacttcc ttgaggtaat tatccatgta agcagggtaa
     1381 ttacttgctg atttgagact ttgtagtcca tcagtaattg gtgtattgac tgctttctca
     1441 tactgttcag cagagatgta gccttgattt ttcatttcag ataagaccaa gtttcggcgg
     1501 tcttgggctg cttctggatg tgaatagggg tcatattggt ttggtgcctg aggcattcca
     1561 gccagcaagg ctaactgagg taaacttaaa ttattgaggt ctttaccata gtagttttga
     1621 gctgctgtct gcattccata gttcccatta gacatgtaga ccttatttat atagtaggtc
     1681 aagatttctt gcttggttgc tttttgttct aactgaatcg ctaaccaagc ttcctgagcc
     1741 ttacgagaaa tagtctggtc ggaagtcgaa gttgaaaagt aagtcaactt aattaactgt
     1801 tgggtgagag ttgatccacc ttggagggaa ttgctttgca gattgcgcaa gaaagctccc
     1861 aggatacgga tggtatcaat ccccctgtgg tcgaagaagc gatggtcttc gatagaaacg
     1921 attgccttaa ccaaatctgt gggaatatca ttagcttggg cattgacgcg gcgttcagaa
     1981 cccaagtcag caatgagttg atttttattg tcgtagattt tactagaagt tgttgcaact
     2041 agtttactct cggataggct aggagccttg ctaacgtagt agaaaaaaac tcctccgcct
     2101 aagacaatgg ctgcgataac caagcttaag aagctaatgc tcagatactt gattaggcgc
     2161 agaatcgttg gtttgttcat cttgttttac cacctaataa atgttctttg ataacattga
     2221 gataaggaat ttgagggaag gcaccagcct tgatttcata tccatattct cgaatatatt
     2281 caagtggcat tgatttttgt cccttatctt gatgatagaa gcgaatcaaa tcgaatgccg
     2341 gcaataagta ggtttcttgc tgagaagaaa agtgaagaag gacaaagcag attccttgtt
     2401 gggcaaggac ttgttccata tgctgaatct gatgtggatg aaaatttttc atcggaatcg
     2461 cacgtttttg ttttgtttcc ttgacttcaa agtcgatgta atatccatta taaacgccag
     2521 aatagtccgt cgttgaagct tgtcgaaaat aggcttcaac aatcttggca cgacttcgtt
     2581 gtggatagtc cacttgtacg atttgaatag gagttggttt cttatgtata acagccaagc
     2641 cctgagacaa atagtagtcg ttggtagcat tgatcatctt ttcaaaagac attcctcgat
     2701 ttgcgaaatt tttgggttga gaaagagatg tttgtctttt ttgtgatgaa actttatgtg
     2761 gatagttgac cataattctc cttattggta caataacatc actttattat accataattt
     2821 gcacagaaag ggttaaaaat ggctacagct ttggttttag gctattctgc ttttgatttg
     2881 ggtttatttt ctgataagga tcctcgtctt aaattgatta aaaaagcgat acgtaaagat
     2941 ttagaggcta tggcagcaga tggggtgtct tggcttgtgt ttacaggaag tttgggtttt
     3001 gaatattggg ttttagaggt tgctcaggag atgaaaaccg aatacggttt ccagttggcc
     3061 accatttttg cttttgaaac ccatggggaa aattggaatg aaggcaatca gatgaaactg
     3121 agtcgcttta agcaggtaga ctttgtcaaa tatgcttatc ctcgttatga acacaagggg
     3181 cagttaagag attatcagca gtttttgctg gaaaacacga ctagttccta tcttttttat
     3241 gatgaagaaa atgaaacaaa actagcttat ttttaccaaa agatgaaaaa tcaagaggac
     3301 tattttataa agagattaac atttgatgaa ttaaatgaac ttgctgaaaa tttttccgaa
     3361 aattgaagct ttgaccttga tttttgtttg ccttttttta tataataata ctagcaagcg
     3421 agaatggaga gagacatggc aagtattatt ttttcagcga aagatatttt tgaacaagag
     3481 tttggacgtg aagtccgtgg ctataataaa gtagaagttg acgagttttt agacgatgtc
     3541 atcaaggact atgaaaccta tgctgccttg gtcaagtcac ttcgtcagga aattgcggat
     3601 ttgaaggaag aattaactcg taaaccgaaa ccttcaccag ttcaagcaga accccttgaa
     3661 gcggcaatta caagttctat gacgaatttt gatattttga aacgcctgaa tagattggaa
     3721 aaagaagttt ttggtaaaca aattttagat aactcagatt tttaagtagt tatttgagat
     3781 gtgcaatttt tggataatcg cgtgaggaga attgcttctc atgaggaaag tccatgctag
     3841 cacaggctgt gatgcctgta gtgtttgtgc taggcgaaac cataagccta gggacgagaa
     3901 atcgttacgg cagttgaaat ggctaagtcc ttggataggc cagagtaggc ttgaaagtgc
     3961 cacagtgacg gagtctttct ggaaacagag agagtggaac gcggtaaacc cctcaagcta
     4021 gcaacccaaa ttttggtcgg ggcatggagt acgcggaaac gaacgtagta ttctgactgc
     4081 tatcagctag agctgttagt ggtagacaga tgattatcga aggaagtggt cctagtcact
     4141 tctggaacaa aacatggctt atagaaaatt gcatataggt tggggctgag aaattttctc
     4201 aacctcattt tttaaagtgg acatatagaa aggtcttgca agactgtaac atgaaaaaag
     4261 aatttaattt aattgcaact gtggcagcag ggcttgaggc tgtcgttggt cgtgaagtgc
     4321 gagagttggg ctacgattgt caggttgaaa atggacgtgt tcgttttcaa ggagacgtga
     4381 gagctattat cgaaaccaac ctttggcttc gggcagcaga tcgtatcaaa attatcgtag
     4441 gaacgttccc agctaagact tttgaagagc tatttcaggg agttttcgct ttagattggg
     4501 aaaattattt accacttgga gctcggttcc cgatttcaaa agctaaatgt gttaagtcca
     4561 aacttcacaa tgagcccagt gttcaggcta tttctaagaa agctgttgtc aagaaattgc
     4621 agaaacacta tgctcgccca gaaggggttc ctttgatgga gaatggtcca gagtttaaga
     4681 ttgaggtctc tattctcaaa gatgtggcaa ctgtcatgat tgatacgacc gggtctagcc
     4741 tctttaaacg tggttatcgt accgaaaaag gtggcgctcc tatcaaggaa aatatggcag
     4801 cagccatttt acaactttct aactggtatc cagacaagcc tttgattgat ccgacctgtg
     4861 gttcggggac tttctgtatt gaggcagtta tgattgctag aaagatggcg ccaggtcttc
     4921 gtcgctcttt tgcatttgag gaatggaact ggatcagcga tcgcttgatt caagaagtgc
     4981 gcacagaagc ggctaaaaaa gtagaacgta agcttgagtt ggatatcatg ggctgtgata
     5041 ttgatgctcg catggtggaa attgctaagg ccaatgctca ggcagctggt gttgcaggag
     5101 acattacttt taagcagatg cgcgtgcagg atttacgttc cgataaaatc aatggagtaa
     5161 tcatttccaa tccgccttat ggtgaacgtt tgtcagatga tgcaggggtg accaagctct
     5221 atgctgagat ggggcaagta tttgcaccgc tgaaaacttg gagcaaattt atcctgacta
     5281 gtgatgaagc ttttgaaagc aagtatggta gccaagcaga taagaagcgt aagttataca
     5341 acggaacctt gaaagtggat ctatatcaat attttggtca gcgtgtcaaa cggcaagagg
     5401 taaaatagaa agggatactc atgagtaaaa aaagacgaaa tcgtcaaaaa aaagaaggtc
     5461 aagaaccgca atttgatttt gatgaagcaa aagagctaac agttggtcaa gctattcgta
     5521 aaaatgaaga agtggaagca ggagtcttgc ctgaggattc cattttggac aagtatgtta
     5581 agcaacacag agatgaaatt gaggcggata agtttgcgac tcgtcaatac aaaaaagagg
     5641 agttcgttga aactcagagt ctggatgatt taattcaaga gatgcgtgag gctgtagaga
     5701 agtcagaagc ttcttcggag gaagttccat cttctgaaga catcttacta cccttgcctc
     5761 tggacgatga ggagcaaggc ttggatcctc tattgctaga tgatgaaaat ccaacagaaa
     5821 tgactgaaga agtggaagag gagcaaaacc tttctcgtct ggatcaagag gactcagaaa
     5881 agaaaagcaa aaaaggcttt attttgaccg ttttggcgct tgtatcagta attatttgtg
     5941 tcagtgctta ttatgtctac cgtcaagtgg ctcgttcgac taaggaaatt gaaacttctc
     6001 aatcaactac agccaatcaa tcggatgtgg atgattttaa tacactttat gacgcctttt
     6061 acacagatag caataaaacg gctttgaaaa atagccagtt tgataaactg agtcaactca
     6121 agaccttact tgataagctg gaaggtagtc gtgaacatac gcttgccaaa tctaaatatg
     6181 atagtctagt aacgcaaatc aaggccattc aagatgtcaa tgcacaattt gaaaaaccag
     6241 ctattgtgga tggtgtgttg gataccaatg ccaaagccaa atcggatgct aaatttacag
     6301 atattaaaac tggaaatacg gagcttgata aagtgctaga taaggctatc agtcttggta
     6361 agagccagca aacaagtact tctagctcaa gttcaagtca aactagcagc tcaagttcaa
     6421 gtcaagcaag ttcaaatacg actagtgagc caaaaccaag tagttcaaat gagactagaa
     6481 gtagtcgcag tgaagtcaat atgggtctct cgagtgcagg ggttgctgtt caaagaagtg
     6541 ccagtcgtgt tgcctataat cagtctgcta ttgatgatag taataactct gcctgggatt
     6601 ttgcggatgg tgtcttggaa caaattctag cgacttcacg ttcacgtggc tatatcactg
     6661 gagaccaata tatccttgaa cgtgtcaata tcgttaacgg caatggttat tacaacctct
     6721 ataagccaga tggaacctat ctctttaccc ttaactgtaa gacaggctac tttgtcggaa
     6781 atggcgctgg tcatgcggat gacttggact actaagcagt cgttacaaaa ttctttcttt
     6841 tcaaaagtaa aaatgataaa ataaaacaaa tgaaacaaga ggagtgtcaa atgacaaaag
     6901 ctaactttgg tgtcgtaggt atggccgtaa tgggtcgtaa ccttgccctt aatattgaat
     6961 ctcgtggtta cacagttgct atctacaacc gtagtaaaga aaaaacggaa gatgtgattg
     7021 cttgccatcc tgaaaagaac tttgtaccaa gctatgacgt tgaaagtttt gtaaactcaa
     7081 tcgaaaaacc tcgtcgtatc atgctgatgg ttcaagctgg acctggtaca gatgctacta
     7141 tccaagccct tcttccacac cttgacaagg gtgatatctt gattgacgga ggaaatactt
     7201 tctacaaaga taccatccgt cgtaatgaag aattggcaaa ctctggtatc aactttatcg
     7261 gtactggggt ttctggtggt gaaaaaggtg cccttgaagg tccttctatc atgcctggtg
     7321 gacaaaaaga agcctacgaa ttggttgcgg atgttcttga agaaatctca gctaaagcac
     7381 cagaagatgg caaaccatgt gtgacttaca tcggtcctga tggagctggt cactatgtga
     7441 aaatggttca caacggtatc gagtacggtg atatgcaatt gatcgcagaa agctatgact
     7501 tgatgcaaca cttgctaggc ctttctgcag aggatatggc tgaaatcttt actgagtgga
     7561 acaagggtga attggatagc tacttgattg aaatcacagc tgatatcttg agccgtaaag
     7621 acgatgaagg ccaagatgga ccaatcgtag actacatcct tgatgctgca ggtaacaagg
     7681 gaactggtaa atggactagc caatcatctc ttgaccttgg tgtaccattg tcactgatta
     7741 ctgagtcagt gtttgcacgc tacatttcaa cttacaaaga agaacgtgta catgctagca
     7801 aggtgcttcc aaaaccagcc gccttcagct ttgaaggaga caaggctgaa ttgattgaaa
     7861 aaatccgtca agccctttac ttctcaaaaa tcatttcata cgcacaagga tttgctcaat
     7921 tgcgtgtagc ctctaaagaa aacaactgga acttgccatt tgcagatatc gcatctatct
     7981 ggcgtgatgg ctgtatcatc cgttctcgtt tcttgcaaaa gattacagat gcttacaacc
     8041 gtgatgcaga ccttgccaac cttcttttgg atgaatactt cttggatgtt actgctaagt
     8101 atcaacaagc agtgcgtgat atcgtagctc ttgcggttca agctggtgtg ccagtgccaa
     8161 ctttctcagc agctattact tactttgata gctaccgttc agctgacctt ccagctaact
     8221 tgatccaagc acaacgtgac tactttggtg cccacactta ccaacgtaaa gacaaagaag
     8281 gaaccttcca ctactcttgg tatgacgaaa aataagtagg tcagccatgg ggaaacggat
     8341 tttattactt gagaaagaac gaaatctagc tcatttttta agtttggaac tccagaaaga
     8401 gcagtatcgg gttgatctgg tagaggaggg gcaaaaagcc ctctccatgg ctcttcagac
     8461 agactatgat ttgattttat tgaacgttaa tctgggagat atgatggctc aggattttgc
     8521 agaaaaattg agccgaacta aacctgcctc agtcatcatg attttagatc attgggaaga
     8581 cttgcaagaa gagctggaag ttgttcagcg ttttgcagtt tcatacatct ataagccagt
     8641 ccttatcgaa aatctggtag cgcgtatttc ggcgatcttc cgaggtcggg acttcattga
     8701 tcaacactgc agtctgatga aagttccaag gacctaccgc aatcttagga tagatgttga
     8761 acatcacacg gtttatcgtg gtgaagagat gattgctctg acccgccgtg agtatgacct
     8821 tttggcgaca cttatgggaa gcaagaaagt attgactcgt gagcaattgt tggaaagtgt
     8881 ttggaagtat gaaagtgcga ccgagacaaa tatcgtagat gtctatatcc gctatctacg
     8941 gagcaagctt gatgttaaag gccaaaaaag ctacattaaa actgtgcgtg gtgttggtta
     9001 caccatgcaa gaatagaaaa gcagttgcag ttgtgtaact gcttttttga ggagttttta
     9061 tatattgaca tacaatctag tttttactac aatcgtttta ggaggatata taaaatgaag
     9121 cttttgaaaa aaatgatgcc aatcgcatta gcagtctttt tctttggttt gctagcgaca
     9181 aatacggtat ttgcgaatac cacaggtggc cgatttgttg ataaggataa tagaaaatat
     9241 tatgtaaaag atgatcataa agcaatctat tggcataaaa tagacggtaa aacttactat
     9301 tttggtgata ttggagagat ggttgtcggt tggcaatact tagaaattcc tggaacaggt
     9361 tatcgtgata atttattcga taatcaacca gttaatgaaa ttggccttca ggagaagtgg
     9421 tactattttg gacaagatgg tgctttgcta gaacaaacag ataaacaagt actagaggca
     9481 aaaacgtctg aaaatacagg aaaagtatac ggtgaacaat atcctctatc tgctgaaaag
     9541 agaacttatt attttgataa taattatgct gtaaagacag gctggattta tgaagagggt
     9601 cattggtatt atttaaataa gctaggaaat tttggcgatg attcttacaa tccactacca
     9661 attggtgaag ttgctaaggg ttggactcaa gattttcatg ttactattga cattgataga
     9721 agcaaacctg ctccatggta ctacctagat ccaacaactg gtattatgca aacaggttgg
     9781 caatatctag gtaataagtg gtactacctc cgttcctcag gagcaatggc cactggctgg
     9841 tatcaggaag gtaccacttg gtattattta gaccagccaa atggcgatat gaaaacaggt
     9901 tggcaaaacc ttgggaacaa atggtactat ctccgttcct caggagcaat ggccactggt
     9961 tggtatcaag atggtttaac ttggtactac ctaaatgcag gtaatggaga catgaagaca
    10021 ggttggttcc aggtcaatgg caactggtac tatgcttata gctcaggtac tttggcagtg
    10081 aatacgaccg tagatggcta ttctgtcaac tataatggcg aatgggttcg gtaatgacag
    10141 ggcgcttata attatattag aacactcgct taatcaaaga agtgactttg ttgtacttga
    10201 cctgacgatt ggggagatta aaagcatgtg aaatctacac atgctttttc gttagttatg
    10261 agtgttgaac ttgactaacc attgacaaaa gataagagca atcaaaataa gatacaaaaa
    10321 tatcaatgct aactgcaccg aaacgcccga tgctatggat agggctaata gggagagcag
    10381 ggacggggcg agaatgtcca ctgtgctcag agcagagccc accgtcccca tcttgtcact
    10441 ggggatatag gcaaagacag ctgcttgtag gcgagggctg agaatgccga taatcgtaga
    10501 actgatgaaa ctggttatga aaattacgat ataggcttga caaaggatac tagttattag
    10561 agccaatagg gaaatctcac agaaaaccaa gaggtgcgtg aaacggatat ttttaaatag
    10621 attactgctg atcatattgc caaggatagc tccacaagac atgatgatgg agagcagggc
    10681 gaggagttgc ccaatgctca gttgtgctag tgtctgttgg atgaagcgga gggcgatcag
    10741 ccgaggggac acatccaaga tggcaatcat actggtcgtc agaaacagta gtatgacggt
    10801 atcttttaac ctcaggagca cagccagcga ttgtttaaga tgttgaaaat atttcttaaa
    10861 actcagtgct gtatgtgaca tttcaattct tttttcaacc tcatacaagg tatgtcgaat
    10921 aacatacagg cccaaaaagg caatgacaaa agtcagagtg ttgataaggg aaatagtttg
    10981 aatacttata acattgataa ggaatgcgcc agccagattg gcgacaatgc ggacaaccct
    11041 catcagagac tgcctgaacc ccatggcatc atgcaggtcg tccttaatta cactgatgta
    11101 gagggcgttc atcatgtagg cagacaggta gctcaaggtg tcagagatga ggttgatgat
    11161 gacaatcata atgactgaaa ctaatgaaaa gggcgacaag acgagaaata ctgtcaaaat
    11221 agcgtagagc aggattttga ttttggcaat acagagtgcg tgtttgactc tattttcttg
    11281 aaaatctcct agaatcccga gaaagagttg cgatagtagg ggaaccatct ctgaaatgga
    11341 aatcagtaaa atcgctagcg gagcgaaatt gtactgagcc acataattga taatggcgag
    11401 gtagaaaata ctgtcgccga atgatgaaaa acagctgttt agcagcaact gtctatatat
    11461 gttgtttgtc caaaataatt tcatacattt ctccttatgt ctgcacatcg aatgggaatt
    11521 tattatttaa tagacaccaa tataccccat gcttcctatt ccgaagtcaa acaaatctgc
    11581 tttaccacta tctccttgaa acatcagtaa accgtgatca tctcgttcag aacatgctaa
    11641 aattacctgt tggatttttt tcatcagtaa tttgttttga ttgtagacag tggtttgtag
    11701 taagctagtt attccgtggc aatatcctgt catcattttt agatgatggt taaaaacaaa
    11761 ttcttgatat ttactaataa tatctttgtt tccgtcacaa tcgtacatac aaagatataa
    11821 gattattccg gaaattcctt cgcaccaaga aagttgtaaa tttcctaaat tttcagtatt
    11881 agaagtaact ttttctaata atttttttaa ttcagtatgg aatgtatgga gatcattata
    11941 gaacatagaa ggttctaaga ctttagaata ggcaaataaa gcatatgcaa ttccacaata
    12001 tccatgagca aagctatagt ctaaaatgct ttctttggct gtatctcttt gtaggaaata
    12061 atgataaatt tccccatata ctattgtgga tgaaagtttt aagagtattg tcattggtaa
    12121 attgatagta ttttattaat gataatagga catcagattt tcccaatgca aagtctattt
    12181 cctctagagt atcataattc tctattaatt tcttagcggt gacgtttgct aattgtagat
    12241 agtattgatt tttactgata gaaaataaat gtaggagtaa ctatagatag cctgcatcac
    12301 caaatagcag tgagtattga tattcatatg tgtgtgtcgt tctaattgtc actgccttct
    12361 tgatgataga gagtatttta gaatccagtt ctggggggta caatttattt agaggaaaca
    12421 gtagtccagc tattccgtgt tggaatgata aattacttac gaaatttcca aattctgttg
    12481 aagaagtgat cctttcttca gaatttacag ttttatctag taaaaatcgt agaacactat
    12541 tacattctgt tttataatca tatttatgtt cctctatttt tttaattttg actaaattat
    12601 ttgtttgact taaatttagt agatattgta accaaaatag ttgctcattt gtgagctgac
    12661 cttgagtatg tgatagttct agtaattgaa taggatcctt taggtagatt caatcaatct
    12721 ataacacaac aacataataa cacttttagg ataacttgtc gaatattata gtaaaatgaa
    12781 ataataacag gacaaatcga tcaggacagt caaatcgatt tctaaaaatg ttttagaagt
    12841 agaggtgtac tattctagtt tcaatctaat atagtatata tttttacatc ttgaattgtc
    12901 aaattaagtg cataactttc ccgtagcata cttcataagg cgttttccac ttaagaaatt
    12961 ttcgtggtcg attatttaga acctctattc acaaaaaaat gttaaactag agttatgaca
    13021 cgcaaagcat atgatactga tttaaatgat caagaatggg ctaagattga accctatttc
    13081 tccaaacacc gcacctataa atggccgaaa cgagtacttg ttaatgagac tttgtacgta
    13141 actaaaacag gttgtcaatg gcgcatgccc cctcacgact ttcctcttta cttaacggta
    13201 tggagtttct ttcgtcgttc tatgacgaca ggttggttcc aggtcaatgg cagatggtac
    13261 tacgcttata gctcaggtgc cttggcagtg aatacgactg tagatggcta ttctgtcaac
    13321 tataatggcg aatgggttca ataatgaaag aagcgattgt gaatggaaac aatcgctttt
    13381 tttgtgaaaa tataataaaa tagataggaa agaattaata cttgtatgaa aaataagacg
    13441 ttttttcgtc tagtaaaagg aaaaaatgac aaaaaaagtt ggtgtcggtc aggcacatag
    13501 taagataatt ttaatagggg aacatgcggt cgtttacggt tatcctgcca tttccctgcc
    13561 tcttttggag gtggaggtga cctgtaaggt agttcctgca gagagtcctt ggcgccttta
    13621 tgaggaggat accttgtcca tggcggttta tgcctcactg gagtatttgg atatcacaga
    13681 agcctgcatt cgttgtgaga ttgactcggc tatccctgag aaacggggga tgggttcgtc
    13741 agcggctatc agcatagcgg ccattcgtgc ggtatttgac tactatcagg ctgatctgcc
    13801 tcatgatgta ctagaaatct tggtcaatcg agctgaaatg attgcccata tgaatcctag
    13861 tggtttggat gctaagacct gtctcagtga ccaacctatt cgctttatca agaacgtagg
    13921 atttacagaa cttgagatgg atttatccgc ctatttggtg attgccgata cgggtgttta
    13981 tggtcatact cgtgaagcca tccaagtggt tcaaaataag ggcaaggatg ccctaccgtt
    14041 tttgcatgcc ttgggagaat taacccagca agcagaagtt gcgatttcac aaaaagatgc
    14101 tgaaggactg ggacaaatcc tcagtcaagc gcatttacat ttaaaagaaa ttggagtcag
    14161 tagccctgag gcagactttt tggttgaaac gactcttagc catggtgctc tgggtgccaa
    14221 gatgagcggt ggtgggctag gaggttgtat catagccttg gtaaccaatt tgacacacgc
    14281 acaagaacta gcagaaagat tagaagagaa aggagctgtt cagacatgga tagagagcct
    14341 gtaacagtac gttcctacgc aaatattgct attatcaaat attggggaaa gaaaaaagaa
    14401 aaagagatgg tgcctgctac tagcagtatt tctctaactt tggaaaatat gtatacagag
    14461 acgaccttgt cgcctttacc agccaatgta acagctgacg aattttacat caatggtcag
    14521 ctacaaaatg aggtcgagca tgccaagatg agtaagatta ttgaccgtta tcgtccagct
    14581 ggtgagggct ttgtccgtat cgatactcaa aacaatatgc ctacggcagc gggcctgtcc
    14641 tcaagttcta gtggtttgtc cgccctggtc aaggcttgta atgcttattt caaacttgga
    14701 ttggatagaa gtcagttggc acaggaagcc aaatttgcct caggctcttc ttctcggagt
    14761 ttttatggac cactaggagc ctgggataag gatagtggag aaatttaccc tgtagagaca
    14821 gacttgaaac tagctatgat tatgttggtg ctagaggaca agaaaaaacc aatctctagc
    14881 cgtgacggga tgaaactttg tgtggaaacc tcgacgactt tcgacgactg ggttcgtcag
    14941 tctgagaagg actatcagga tatgctgatt tatctcaagg aaaatgattt tgccaagatt
    15001 ggagaattaa cggagaaaaa tgccctggct atgcatgcta cgacaaagac tgctagtcca
    15061 gccttttctt atctgacgga tgcctcttat gaggctatgg actttgttcg ccagcttcgt
    15121 gagaaaggag aggcctgcta ctttaccatg gatgctggtc ccaatgttaa ggtcttctgt
    15181 caggagaaag acttggagca tttatcagaa attttcggtc atcgttatcg cttgattgtg
    15241 tcaaaaacaa aggatttgag tcaagatgat tgctgttaaa acttgcggaa aactctattg
    15301 ggcaggtgaa tatgctattt tagagccagg gcagttagct ttgataaagg atattcccat
    15361 ctatatgagg gctgagattg ttttttctga cagctaccgt atctattcag atatgtttga
    15421 tttcgcagtg gacttaaggc ctaatcctga ctacagcttg attcaagaaa cgattgcttt
    15481 gatgggagac ttcctcgctg ttcgtggtca gaatttaaga cctttttctc tagaaatctg
    15541 tggcaaaatg gaacgagaag ggaaaaagtt tggtctaggt tctagtggca gcgtcgttgt
    15601 cttggttgtc aaggctttac tggctctgta tgatgtttct gttgatcagg agctcttgtt
    15661 caagctgact agcgctgtct tgctcaagcg aggagacaat ggttccatgg gagaccttgc
    15721 ctgtattgtg gcagaggatt tggttctcta ccagtcattt gatcgccaga aggtggctgc
    15781 ttggttagaa gaagaaaact tggcgacagt tctggagcgt gattggggct tttcaatttc
    15841 acaagtgaaa ccaactttag aatgtgattt cttagtggga tggaccaagg aagtggctgt
    15901 atcgagtcac atggtccagc aaatcaagca aaatatcaat caaaattttt taagttcctc
    15961 aaaagaaacg gtggtttctt tggtcgaagc cttggagcag gggaaagccg aaaaagttat
    16021 cgagcaagta gaagtagcca gcaagctttt agaaggcttg agtacagata tttacacgcc
    16081 tttgcttaga cagttgaaag aagccagtca agatttgcag gccgttgcca agagtagtgg
    16141 tgctggtggt ggtgactgtg gcatcgcctt gagttttgat gcgcaatcaa ccgaaacctt
    16201 aaaaaatcgt tgggccgatc tggggattga gctcttatat caagaaagga taggacatga
    16261 cgacaaatcg taaggacgag catatcctct atgcccttga gcagaaaagt tcctataata
    16321 gctttgatga ggtggagctg attcattctt ccttgcctct ttacaatctg gatgaaatcg
    16381 atctttcgac agagtttgct ggtcgaaagt gggactttcc tttttatatc aatgccatga
    16441 ctggtggaag taataaggga agagaaatca atcaaaagct ggctcaggtg gcggaaacct
    16501 gtggtatttt atttgtaacg ggttcttata gcgcagccct caaaaatcca acggatgatt
    16561 ctttttctgt caagtctagt catcccaatc tcctccttgg aaccaatatt ggattggaca
    16621 agcctgtcga gttaggactt cagactgtag aagagatgaa tcctgttcta ttgcaagtgc
    16681 atgtcaatgt catgcaggaa ttactcatgc ccgagggaga aaggaagttt agaagctggc
    16741 aatcgcatct agcagattat agcaagcaaa ttcccgttcc tattgtcctc aaggaagtgg
    16801 gctttggaat ggatgccaag acaatcgaaa gagcctatga attcggtgtt cgtacagtgg
    16861 acctatcggg tcgtggtggc accagctttg cctatatcga aaaccgtcgt agtggccagc
    16921 gtgattacct caatcaatgg ggtcagtcta ccatgcaggc ccttctcaat gcccaagaat
    16981 ggaaagataa ggtcgaactc ttggttagtg gaggggttcg gaatccgctg gatatgatta
    17041 agtgcttggt ttttggtgct aaggctgtgg gattgtcacg aaccgttctg gaattggttg
    17101 aaacctacac agttgaagaa gtgattggca ttgtccaagg ctggaaagca gatctacgct
    17161 tgattatgtg ttcccttaac tgtgccacca tagcagatct acaaaaagta gactatcttc
    17221 tttatggaaa attaaaagaa gcaaatgatc agatgaaaaa ggcgtaacca gcgccttttt
    17281 ttccatcctc agactgaggt gacttttttg aattgtgata aaatagaagg gagaggatga
    17341 acctatgaga aaatttaaaa tctttttatt tatcgaagcc tgtcttctga caggagctct
    17401 gattttgatg gtatcagagc atttttcgcg ttttctgctg atactattcc tctttttgct
    17461 tttgattcgc tactacactg gtaaagaggg aaataatctt cttttagtag cggcaaccat
    17521 tctcttcttt ttcatcgtta tgctcaatcc ttttgtgatt ctagctattt ttgttgcggt
    17581 tatctatagc ctctttcttc tttacccgat gatgaaccag gaaaaagagc agaccaattt
    17641 ggtttttgaa gaggtcgtga cggttaagaa ggagaaaaat cgttggtttg gaaatcttca
    17701 tcatttttca agctaccaga cttgccaatt cgatgatatc aatctctttc gcttcatggg
    17761 caaggacact attcatctgg agagggtcat cttaaccaat catgacaatg tcattatcct
    17821 cagaaagata gtaggaacga ccaaaatcat cgtacctgta gatgtggaag tcagtctcag
    17881 cgttaactgt ctctatgggg atttgacttt tttcaaccag cccaagcgag ccctccgcaa
    17941 tgaacactat catcaagaaa caaaagacta tctcaagagt aacaagagtg tcaagatttt
    18001 cttgaccact atgattggtg atgtggaggt ggttagagga tgaaaaaaca agcctatgtc
    18061 attattgctc tcacctcctt cctgtttgtc ttttttttct cccacagctt gctggaaata
    18121 cttgattttg actggtctat ctttttgcac gatgtcgaaa aaacagaaaa atttgtcttt
    18181 ttattgttgg ttttcagcat gtccataacc tgtctcttag ccctgttttg gcgagggatc
    18241 gaagagcttt ctctaagaaa aatgcaggct aatctcaagc gtttattggc agggcaagaa
    18301 gtagttcagg ttgtagatcc agatttggat gccagtttca agtccttatc aggtaaactt
    18361 aaccttttga cagaggctct tcaaaaagca gaaaatcaga gtcttgctca ggaagaggaa
    18421 atcatcgaga aggaacggaa gcgaattgct cgggatttgc acgatacagt cagtcaggag
    18481 ttgtttgcgg cccacatgat tttatcgggt atcagtcagc aggctttgaa attggataga
    18541 gaaaagatgc agacccagtt gcagagtgtc acagctattt tagaaacagc ccagaaggat
    18601 ttgcgggttt tgctcttgca tttgcgacca gttgaactgg agcagaagag cttgatagaa
    18661 gggattcaaa ttctcttaaa agagcttgag gacaagagtg atcttagggt tagtctcaag
    18721 cagaatatga cgaaattgcc taagaaaatc gaggagcata ttttccgtat cctgcaagag
    18781 ttgattagca atacgctccg ccatgcccag gcatcttgcc tagatgtcta cctctatcag
    18841 acagatgttg aattgcaact gaaggtggtg gacaatggga ttggtttcca gttagggagc
    18901 ttagacgact tgagttatgg actgcgaaat atcaaggagc gggttgaaga tatggcaggg
    18961 acggttcagt tattaacagc tcccaagcaa gggctggcag ttgatatccg tattcccctg
    19021 ttagataagg aatgataaag gagtaaagat gaaaatttta ctagtagatg accatgaaat
    19081 ggtccgtttg ggcttgaaaa gctactttga cctccaagac gatgtagaag ttgtgggtga
    19141 ggcgtccaac gggtctcaag ggattgactt ggccttggaa ctgcgtccag atgtcattgt
    19201 catggatatt gtcatgcctg agatgaatgg gattgacgcg accttagcaa tccttaaaga
    19261 atggcctgaa gccaagattt tgattgtgac ctcttatttg gacaatgaaa aaatcatgcc
    19321 agtcttagat gctggtgcca aaggctatat gctcaagact tctagtgcag atgaattgct
    19381 tcatgccgtc agtaaggtag ctgctggcga gctggccatt gagcaagagg ttagcaagaa
    19441 ggttgaatac caccgcaatc atatggaact tcatgaagaa ttgactgcgc gtgagcgaga
    19501 tgttctccaa ctcatcgcca agggctacga aaatcagcgc atcgcagatg acctctttat
    19561 ctctctcaag acggtcaaga cccacgtgtc caatattctt gccaaacttg aagtcagcga
    19621 tcgtacccag gcggctgtct atgcctttca gcaccatttg gtggggcaag aggagtttta
    19681 gatgagttta gcagatttac ttgaggagct agaagcagca aaagactcta aaaagcaagg
    19741 cccatggaag cctatatgcg ccatcaattt tcttttctag gtattgcggt gcctgaaaga
    19801 aataaactct ataaaaatat tttccagaag cgaaaaaaac aaagattatc gattgggatt
    19861 ttgcagacac ttgctgggaa aaggagccta gaaaatacca atatgtggct gctaactatt
    19921 tgaaagcaat gcagtcttat ctaaaggaaa ccgatttgcc taagctagag cagttagtcg
    19981 tgacaaaatc ctggtgggac acggtagata tcctagatcg agtagtaggg agtttggtgt
    20041 ataaacaccc tgaactagaa gaaataatct taatattctt cgaaaatctc ttcaaaccac
    20101 gtcagctcta tctgcaacct caaaacagtg ttttgagcaa tctgtggcta gcttcctagt
    20161 ttgctctttg attttcattg agtataaaat ggagcctatc agataatatc tggctgagac
    20221 gtgtcgctat tgaccaccag ttgttaagaa aagagaagac caatactcaa ttaatggaaa
    20281 agattctcct tcataacttg aaccaaacag aattttttat caataaagcc attggctgga
    20341 ctctgcgaga ctactccaaa acgaatccca cttgggtaac atgctttatt gagaaaaaca
    20401 aggaaagaat ggctgaactt agtatcaaag aagcaagcaa gtacctctag cgtgattgaa
    20461 aagcgcagtc attaattgaa aagtttacct gtttatgtga taatggaggg tatttaaaga
    20521 aggtggtaga tttcttgatt ctatagtaga ttaagaaatt tagaatagta cgctataatt
    20581 acattaggag gatacaataa tgaagaaaac tgtttataaa aaattgggta tttcaattat
    20641 tgcgagtact ttattggcta gccagttatc gacagtatct gctttgagtg ttatttctag
    20701 tacaggtgaa gaatatgagg taagtgagac actagaaaaa ggtccagagt ctaatgattc
    20761 ttcattatct gagatttcac caacgtatgg ttcatactac caaaagcaat cagaagtatt
    20821 atcggtaatg atgatttgat taaaattgat aatactttac agtatccgta ttcgacttca
    20881 gctatggttt tatctaagta ttatggagta gccgatggaa tgaatgtaga agggagggga
    20941 agtgcgaatt ttattaaaga taatgtgtta attacagcgg ctcacaacta ctacagacat
    21001 gactatggga aagaagcgga tgatatttat gttcttccgg ctgttagtcc aagtcaagaa
    21061 ctatttggaa agatcaaagt aaaggaagtt cgttatttga aggaatttag aaatttaaat
    21121 tctaaggatg caagggaata tgacttggct ttattaattc tagaagagcc cattggtgca
    21181 aaattaggga ctttgggtct tcctactagt caaaaaaatt tgacaggaat aactgtgact
    21241 atcacaggct atccatcata taattttaaa attcatcaaa tgtatacaga taaaaaacaa
    21301 gttttaagtg atgatggcat gttcttggat taccaagttg atactttaga ggggtctagt
    21361 ggatctacag tttatgatgc tagtcaccgt gtagtaggag tgcatacttt aggagatgga
    21421 gctaatcaaa ttaacagtgc agttaaatta aatgaacgaa atttgccatt tatttattcg
    21481 gttcttaaag gttactctct tgaaggatgg aagaaaataa atggtagttg gtactattat
    21541 agacaacatg ataaacaaac gggttggcag gagataaatg atacttggta ttatttagac
    21601 agttccggta agatgcttac agattggcaa aaagtaaatg gaaactggta ttatctcaat
    21661 tcaaatggag caatggttac aggtagccaa actatcgatg gtaaagttta taacttcgct
    21721 tcatctggtg agtggatttg atgttggagg atatataaaa tgaagctttt gaaaaaaatg
    21781 atgcaagtcg cactagccac atttttcttc ggtttgctag ggaccagtac agtatttgca
    21841 gatgattctg aaggatggca gtttgtccaa gaaaatggta gaacctacta caaaaagggg
    21901 gctctaaaag aaacctactg gagagtgata gatgggaagt actattattt tgatccttta
    21961 tccggagaga tggttgtcgg ctggcaatat atacctgctc cacacaaggg ggttacgatt
    22021 ggtccttctc caagaataga gattgctctt agaccagatt ggttttattt tggtcaagat
    22081 ggtgtcttac aagaatttgt tggcaagcaa gttttagaag caaaaactgc tacgaatacc
    22141 aacaaacatc atggggaaga atatgatagc ccagcagaga aacgagtcta ttattttgaa
    22201 gatcagcgta gttatcatac tttaaaaact ggttggattt atgaagaggg tcattggtat
    22261 tatttacaga aggatggtgg ctttgattcg cgcatcaaca gattgacggt tggagagcta
    22321 gcacgtggtt gggttaagga ttaccctctt acctatgatg aagagaagct aaaagcagct
    22381 ccatggtact acctagatcc agcaactggc attatgcaaa caggttggca atatctaggt
    22441 aataagtggt actacctcca ttcgtcagga gctatggcaa ctggctggta taaggaaggc
    22501 tcaacttggt actatctaga tgctgaaaat ggtgatatga gaactggctg gcaaaacctt
    22561 gggaacaaat ggtactatct ccgttcatca ggagctatgg caactggttg gtatcaggaa
    22621 ggttcgactt ggtactatct aaatgcaagt aatggagata tgaaaacagg ctggttccaa
    22681 gtcaatggta actggtacta tgcctatgat tcaggtgctt tagctgttaa taccacagta
    22741 ggtggttact acttaaacta taatggtgaa tgggttaagt aatgaaggct aattgtaaac
    22801 tgtgatggat acttaacttt gtataatagg tggataaaag tcttcacaat caaaaaacgc
    22861 atagtatcaa ggtttttctg tactgccccc caaaagttag acaaataatt tatccaaagg
    22921 atttagttct gtactgcaca ggactaagtc cttttagttt taccttaatt ctcttgttgt
    22981 tgtaataatc aatatagtct acaatagctt gttccaattg cttaagcgac tgaaacgact
    23041 tctcataacc gtaaaacatt tccgatttca gaatcccaaa gaaggattcc accatagtgc
    23101 ttctctttga atgcctgttc caacattgtt tgtacttgtt ctaaattagg cgaacaagaa
    23161 agattaaaag caataatttc actgttaaag ccatctaaaa ctggtggtaa gtaaagcttt
    23221 tgagtacttg ctggaatggc aaattctgtc acatctgtgt agcacttttc cattgtttta
    23281 gagccttcaa attggccttg aatgagattc tctgccttct tgccaacgtc tcctttatga
    23341 gaagaatatt ttcgtttctg tcgcatttta gcttgtaaat tgagtacttt tatcaagcct
    23401 tgaactcttt tatgatttac cagataagca cgatttctta gttctaaatg aacccggcga
    23461 taagcataat ttccttt
//
LOCUS       DAVDHC010000033        23095 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVDHC010000033 DAVDHC010000000
VERSION     DAVDHC010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.033"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            1..1070
                     /locus_tag="VUR43_001757"
                     /pseudo
     CDS             1..1070
                     /locus_tag="VUR43_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1186..1989)
                     /locus_tag="VUR43_001758"
     CDS             complement(1186..1989)
                     /locus_tag="VUR43_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET5413409.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(2592..3971)
                     /locus_tag="VUR43_001759"
     CDS             complement(2592..3971)
                     /locus_tag="VUR43_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET5413410.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTP"
     gene            complement(4022..4186)
                     /locus_tag="VUR43_001760"
     CDS             complement(4022..4186)
                     /locus_tag="VUR43_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET5413411.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            complement(4267..6918)
                     /locus_tag="VUR43_001761"
     CDS             complement(4267..6918)
                     /locus_tag="VUR43_001761"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET5413412.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWVYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVVHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ECDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(6911..7489)
                     /locus_tag="VUR43_001762"
     CDS             complement(6911..7489)
                     /locus_tag="VUR43_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET5413413.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQHQPNELNH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(7489..8049)
                     /locus_tag="VUR43_001763"
     CDS             complement(7489..8049)
                     /locus_tag="VUR43_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5413414.1"
                     /translation="MARTELPDKIEIERLVLRVRTVADAEDIHVYASLPEVAYPAGFL
                     PVKTLEDEIYYLGHILPNRNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            complement(8036..8527)
                     /locus_tag="VUR43_001764"
     CDS             complement(8036..8527)
                     /locus_tag="VUR43_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET5413415.1"
                     /translation="MTTCSSSCSLGDWVVIGVVARENAAEQIKQYQKFTVNISDETSM
                     LAMEQTGFISHQEKLERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFA
                     KILERLVAPELLDEKGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKD
                     GKN"
     gene            complement(8897..9292)
                     /locus_tag="VUR43_001765"
     CDS             complement(8897..9292)
                     /locus_tag="VUR43_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET5413416.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGINSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(9388..9642)
                     /locus_tag="VUR43_001766"
     CDS             complement(9388..9642)
                     /locus_tag="VUR43_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET5413417.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(9652..10986)
                     /locus_tag="VUR43_001767"
     CDS             complement(9652..10986)
                     /locus_tag="VUR43_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET5413418.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEVFEAFAIEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDVYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDENGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(10986..11219)
                     /locus_tag="VUR43_001768"
     CDS             complement(10986..11219)
                     /locus_tag="VUR43_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET5413419.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            11250..11324
                     /locus_tag="VUR43_001769"
                     /pseudo
     CDS             11250..11324
                     /locus_tag="VUR43_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(11532..11672)
                     /locus_tag="VUR43_001770"
     CDS             complement(11532..11672)
                     /locus_tag="VUR43_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413420.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(11669..11851)
                     /locus_tag="VUR43_001771"
     CDS             complement(11669..11851)
                     /locus_tag="VUR43_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413421.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(11853..12632)
                     /locus_tag="VUR43_001772"
     CDS             complement(11853..12632)
                     /locus_tag="VUR43_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413422.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELDPKDIPTL
                     LEQGTTTLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEALWTSREELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLKIFGVNLTKGGLAKGIGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            complement(12911..13261)
                     /gene="rbfA"
                     /locus_tag="VUR43_001773"
     CDS             complement(12911..13261)
                     /gene="rbfA"
                     /locus_tag="VUR43_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET5413423.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(13512..16304)
                     /gene="infB"
                     /locus_tag="VUR43_001774"
     CDS             complement(13512..16304)
                     /gene="infB"
                     /locus_tag="VUR43_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET5413424.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(16321..16620)
                     /locus_tag="VUR43_001775"
     CDS             complement(16321..16620)
                     /locus_tag="VUR43_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET5413425.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(16613..16906)
                     /locus_tag="VUR43_001776"
     CDS             complement(16613..16906)
                     /locus_tag="VUR43_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET5413426.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(16928..18064)
                     /gene="nusA"
                     /locus_tag="VUR43_001777"
     CDS             complement(16928..18064)
                     /gene="nusA"
                     /locus_tag="VUR43_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET5413427.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(18108..18587)
                     /gene="rimP"
                     /locus_tag="VUR43_001778"
     CDS             complement(18108..18587)
                     /gene="rimP"
                     /locus_tag="VUR43_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET5413428.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVRIPYSLVSKARLAVKL"
     gene            complement(18713..19348)
                     /gene="trmB"
                     /locus_tag="VUR43_001779"
     CDS             complement(18713..19348)
                     /gene="trmB"
                     /locus_tag="VUR43_001779"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET5413429.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(19345..20139)
                     /locus_tag="VUR43_001780"
     CDS             complement(19345..20139)
                     /locus_tag="VUR43_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET5413430.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(20300..20911)
                     /locus_tag="VUR43_001781"
     CDS             complement(20300..20911)
                     /locus_tag="VUR43_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5413431.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGFFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            complement(21062..21295)
                     /locus_tag="VUR43_001782"
     CDS             complement(21062..21295)
                     /locus_tag="VUR43_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413432.1"
                     /translation="MYKHLFFLDSKTLDWLTPYILVLASDTIAFNVFVLTFVSAVIFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(21337..22026)
                     /locus_tag="VUR43_001783"
     CDS             complement(21337..22026)
                     /locus_tag="VUR43_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5413433.1"
                     /translation="MKKYQLLFKISAVFSDLFFVFGLSQMTLIVQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFAGLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            complement(22078..22461)
                     /locus_tag="VUR43_001784"
     CDS             complement(22078..22461)
                     /locus_tag="VUR43_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET5413434.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
BASE COUNT         6773 a         5036 c         4206 g         7080 t
ORIGIN      
        1 ataaagtctg acatgaaggc tggactaaag atagagtttc tcttgaatac ggcctcccaa
       61 gtcgtacgat acttcttaac tggctagcac aatacaggaa aaacgggtat actattgttg
      121 agaaaacaaa agggagagta cctgagagcg gagaatgcca tcctaaaaaa gttaagagaa
      181 ctccgattga aggaggaaaa agagaaagaa gaaagacaga aattgttcaa gaattaatga
      241 ctgagttttc gttagttctt cttctaaaat ccattaaact agctcgttgg acctactact
      301 atcacttgaa acagctagac aaaacagata aggaccaaga gcttaaagct gaaattcaat
      361 ccatttttat cgaacacaag ggaaattatg cttatcgtcg gatttattta gaactaagaa
      421 atcgtgctta tctggtaaat cataaaagag ttcaaggctt gatgaaagta ctcaatttac
      481 aagctaaaat gcgacagaaa cgaaaatatt cttctcataa aggagacgtt ggcaagaagg
      541 cagagaatct cattcaaggc caatttgaag gctctaaaac aatggaaaag tgctatacag
      601 atgtgacaga atttgccatt ccagcaagta ctcaaaagct ttacttatca ccagttttag
      661 atggctttaa cagcgaaatt attgctttta atctttcttg ttcgcctaat ttagaacaag
      721 tacaaacaat gttggaacag gcattcacag agaagcacta cgagaatacg attctccata
      781 gtgaccaagg ctggcaatac caacacgatt cttatcatca gtttcttgag ggtaagggaa
      841 ttcaagcatc catgtcacgt aagggaaaca gccaagacaa cggtatgatg gagtccttct
      901 ttgggattct gaaatcggaa atgttttatg gctatgagaa aacatttaaa tcacttaatc
      961 aattggaaca agctattgta gactatattg attactacaa caataaacga attaaggtaa
     1021 aactaaaagg acttagcctt gtgcaataca gaactaaatc cttcggataa attatttgtc
     1081 taactttttg gggtcagtac acctaaaact ttgatgatat acgttttctt gtgagaatat
     1141 ttacttcatt tttgcctaaa attcaatgtt tactcagtat ttggattatg aaaaatcgag
     1201 gtctaaatct agatacattt tttctgaaga caaatcattt tgaccaccga gcaagagatt
     1261 ttcaaaaaaa gctgttaaaa actcagaacg tcgctgtaaa atctttgcat tatctaatac
     1321 caaggcatca cgaaaatatt tggaatgttg ctgaaatggt gtattatcaa tatcaaaacc
     1381 aaactcacga agatactgaa tcaaaaagac cgttactgtc cgagtgtttc cttcgcgaaa
     1441 tggatgaatc tgccagattc ctgaaataaa atgctggatt tgtttaacca catccgcctg
     1501 agttagtgtc gcatatgcaa cttgtttttc ctgattaaaa tcataatcta aggtcatttg
     1561 aatcatggag taatcagagt acacaacact ttcaccattc aaaacaggtt cattctttgt
     1621 gatattggtc tgacgaaatt gccccaccgg aatagagggt tcaaatatat cttgaaacaa
     1681 ctccttatga atagcaagta aggtcgcagg actaaagcta aagcctcttc gagacaatag
     1741 ttctacaata cgtagagaaa ccaagtctgc ctcttccgta cttgcatcaa tagtatggtg
     1801 ataagccgtt gcatcctcat aaacctgctc ataagtcagt tctccccggg actgtttctc
     1861 agccaaagat tccatatacg ctgatggcac tagattgtca actttctgca gaccaaaacc
     1921 tatccgccat aaatcacgct tcgcttcata agacaagttt ggattgtcaa tgttgtaagt
     1981 tgattgcata gaaatatcct ttcaattgtt tttctgtgtc atcggtaaat tgtgaaatag
     2041 gtatggaatt ggcgaaaatt ataaaaatcc ttcacaatag gttctatgaa atatatatac
     2101 ttcatcttaa tagtgagcaa gctaaactta gcatttcatg ccctcatatg ggatgttctt
     2161 taactaaata atatgattat cgagatatat ctggataaat gaactaataa gtctgacgcg
     2221 tagacttatc aaagtcattg gcatacacca ctatgaactc gttgatctgt tcaaatccca
     2281 acacattacc tgagaagaaa gttgcaatgt tgtttttggt gcgggtttga atttaaaaat
     2341 ttgttatgta gtacctaatc taaggaatta gaacaatgcc tctaattttt ctttaataca
     2401 ctgaaacatt gatgattctg gctgtatttt tgaaacagct cttctttgct cctggaaaat
     2461 atcttcagaa gttatattct ctattcctaa cgctacttga atttttttct aaaatattct
     2521 tttccgttgc catctttaga aaaatcataa ccttccctat ctacgctgtt acataaatta
     2581 gctaaaaaaa actatggggt tgggaaagga agataagaaa cgtatttagc ccaataatct
     2641 ataaagcttc tttgtttcgc aattaattca atattatttt tttgcccttt attacctgaa
     2701 acattaaatt tgattggaca tcccgttatc aattttataa tatcatcaag atttttatta
     2761 tctgattcag gaattttatc tgatataaca acaccatttt caagatagtt cattaaatta
     2821 tttgattcac taacattagt gttttgatct ccatcaagcc aaaaataatg gttatcggaa
     2881 tctaaatacg atgagtttaa aatattatta caaattattt gatttgctcc accagggata
     2941 tatctcacta ctaaattctg tttaagattc tcactacctg aatgagtgat aacaaactct
     3001 agaatatatt tagctagtct atcttcaaca taaatcatct tcctagaatg atacacatca
     3061 cctaattcaa aaaatgcatc ctgataatca atattttcaa taacatctac cttttctccg
     3121 tttttcacta aaagtttcac ggcttctcta ggaaaatctt ttataagttg tgtagaatgt
     3181 gtagtgataa taatttgatg ttttttattt aaacactctt gaagtaaaaa ctctttaaat
     3241 ttatagattg cactcggatg aagtgagatt tcaggttcat ctattaatat taatgaattt
     3301 gattgcgcat ttactatatc atttactaac aaaataattc tagcctcacc tgttcctgca
     3361 aaagcctcag aatattcttt tccagatttt ttcatccaaa tagttttgga agcttttata
     3421 tcatcacctt ttgaatacaa cttatgtgtt aaaatttgaa tgtctgtata agattcatcc
     3481 attatttcac taataatttc acaaacttta tcatcaactt taacattatc tataaccatt
     3541 tcctttttat aacgcgtata gctacttgta ttattcttta aaatatcagc aactggttta
     3601 gatcgtaatc ttataaaatc ttgtttacta cgttgagtag aaattttttt aaaattatag
     3661 tgatagaaaa ataaatcaaa agcagaaaca tattctttac aatcacaaaa gacaacattt
     3721 ttttcaatgc catcccatct gtctgtcgaa gaacttccaa tatatttatt tttgggtaat
     3781 ctttccatct catattgttt ttgaggagca tatggttccc aataatctaa tccttttttt
     3841 gttccagaac ggcctttaag aacttctaca tttctagaag ctttaacgtt ataatatgaa
     3901 tagattaaac attgtttccc atccacttca tctatttgat caacatttgt actaaaccaa
     3961 tattcagaca cacttttatt ggctggagaa ccatataaag cttgtaaaat tgaagtttta
     4021 tttactccat atctattaca gacacctcag gattatttaa cttataagtt ttaacagcta
     4081 cggaatcaat ttcaacagca acttgaacat ctatgcctga ttttttaagg ccacttgtag
     4141 tgccacctgc accgctaaat aaatcaatag caacaatttt ccccatagta ttctcctaaa
     4201 gtttctcctt tttattataa cattatcaaa tgtaaaaccc aacccgagag ggttaggttt
     4261 ttaacatcat ttcaccaact tcttcatctc atcaatacgt gcgacggtcg cgtcatattt
     4321 agcttggtag tcagcttgtt tgtcgcattc tttttggacg acttctggtt tggcgttggc
     4381 tacgaagcgt tcgttagaga gtttcttacc aaccatgtcc agttcttttt gccatttagc
     4441 aagttccttg tcgagacggg ccagttcttc ttcaacattg aggagatcgg ccagtggcag
     4501 gtagatttct gctcctgtga tgacacttga catagccagt tcaggtgcag ggatggttga
     4561 tgcgatttcc aaatgttctg gatttgtaaa gcgtttgatg tagttgacat tgctgttaaa
     4621 gaaggcttcc aagtcgctat cgcttgtctt aacaaggatg gtgataggtt tgcttggtgc
     4681 tacatttact tccgcacgcg cattacgaac ggcacggatc aagtctttga gactttccac
     4741 accagtgtgg gcagcaaggt cctcaaaggc tgggttgaca gttgggtatg ctgctgtcac
     4801 gatagagcct tcagcgtact gaccaaagat ttcttctgtc acgaatggca tgattgggtg
     4861 aagaagacgg aggattttat ccagcgtata gaggagaaca gatcgagtaa tgaccttatc
     4921 gtcttcattg tcgctgtaaa gaacttcctt ggtcaactca acataccagt tggcaaattc
     4981 ttcccaaatg aagttgtaga ggatgtggcc agcaacacca aactcaaact tatcaaagtt
     5041 agcagttgct tttccaatcg tttcattgag gttgtggaga atccagcggt ccgtcacatt
     5101 accagcctca cctgttgcaa cttttgtgac attgtcatgc accacatcca gcgtcaaacc
     5161 ttcattgttc ataaggatgt agcgagagat gttccagatc ttgttaatga agttccatga
     5221 agcatccatt ttctcataag agaaacgcac gtcttgtcct ggcgcagaac cgtttgaaag
     5281 gaaccatcga agggcatcgg caccgtattt ctcgataaca tccattgggt caatcccgtt
     5341 accgagagac ttagacatct tgcgtccttg ctcgtcacga ataagaccgt ggataaggac
     5401 gttttggaat ggttgacggc ctgtgaattc caatgactgg aagatcatac gagacaccca
     5461 gaagaagatg atgtcgtaac ctgttaccaa ggttgaagtt gggaaataac gtttaaagtc
     5521 ttctgagtcg acttcaggcc agcccatggt tgaaaatggc cagagggcag aactgaacca
     5581 agtatccaag acgtcttcgt cctgagtcca tccgtcacct tctggagctt cttcgccgac
     5641 atacatttca ccatcagcat tgtaccaggc agggatttgg tgaccccacc aaagctgacg
     5701 agagataacc cagtcgtgga cattttccat ccattgaagg aaggtatcgt tgaaacgagg
     5761 tgggtagaat tcgaccttgt cctctgtgtc ttggttggca atggcgttct tagccaattg
     5821 gtccatcttg acgaaccatt gagtagacaa gcgtggctca actacgacac ctgtccgttc
     5881 tgagtgaccg actgaatgga cacgtttttc gattttgaca agggcaccga tttcttccaa
     5941 cttagcaacg actgccttac gagcttcaaa acgatccatg cctgaaaatt caaaggcaag
     6001 ctcattcata gttccgtcgt cgttcatgac gttgacttgt ggcaagttat gacgttggcc
     6061 aaccaagaag tcatttggat cgtgggcagg tgtgattttc acgacaccag taccaaactc
     6121 aggatctgcg tgctcatctc caacgattgg gatgagttta ttagcgattg gaaggatgac
     6181 gtttttacca atcaagtcct tgtagcgcgg gtcttctgga ttaaccgcaa ccgcaacgtc
     6241 cccaaacata gtctcaggac gagttgtagc aacttcaagg gcgcgtgaac catcttccag
     6301 catgtaattc atgtggtaga aggcaccttc cacatccttg tgaatcacct caatatcaga
     6361 aagggctgtg cgagctgctg ggtcccagtt gatgataaac tcaccacggt agacccagcc
     6421 tttcttgtaa aggtccacaa agaccttacg aacagctttt gacaaacctt cgtcaagagt
     6481 gaaacgctca cgagaatagt ctacagagag ccccatcttg ccccattgtt ccttgatggt
     6541 agtggcatat tcgtctttcc attcccagac tttcgtcaag aaagactcac gaccaaggtc
     6601 atagcgggaa atgccctcac cacgcaagcg ctcctcaacc ttagcctgag tcgcaatacc
     6661 agcgtggtcc attcctggaa gccaaagggt atcaaaacct tgcatgcgtt tttgacggat
     6721 gataatatct tgcaaagttg tatcccaagc gtgaccaagg tgaagtttac ctgtaacgtt
     6781 tggtggtgga ataacgattg aataaggctt agccttttga tcgcctgaag gcttgaaaac
     6841 atcagcatca agccattttt gataacgacc agcctcaacc tcggctggat tgtatttagg
     6901 tgaaagttct ttagacatgt gtgtgtcctt tctctatttt gtttatttta ttttgaattt
     6961 gcttagcagc ttcttctgca gacaaattcg tattatttat tttaaagtag tggttcaact
     7021 cattcggttg atgttgggaa tttaattgaa gtgtttcagc ggtctctata atttctcttt
     7081 cagatacctc aatatgtcgt tttaagggtt tgtactttaa tcgattctcc gttcgatttc
     7141 gacgtatgca ctcttcaaga cttgtttcca actcaacaaa aagaatctct tgatgataat
     7201 catccaacaa actctgaatt tgctttaaat atatcagatg atactgattt gaaaaatcaa
     7261 ttacatctgt taaaattact gatcgctgat ttcttgcact cgctccaagg aatgaaaaag
     7321 tgattccacg aacaaattcc cacatttcct ctgtatagtc ctgatagatt tctagtgcaa
     7381 aatcaatggc ttgatggtta taaaataggg tagcatccgt cagtcgagat aattcttgac
     7441 caatggtcat ttttcctgat gctggagcac caatgatgaa aagatgcatc aaatcacccc
     7501 ccactcactc ttcagcaagg catatctcaa atcatcacag cagttgcctt gagcatcttt
     7561 acggtctctt atgcgagctt cgagggtaaa gccaagcttt tccgcgactc gttgactttg
     7621 aaggttatat ccaaagcaag ttagttcaat cttgtgaaga cccaaatctt taaaggctaa
     7681 gtcaatcaag gcacgcgcag cttctggcac ataacctcgc ccccaatagt ctgggtgtaa
     7741 ggtatagccg atttccagca catcatcttc atggcgatgg ttgaaatcga cagagccaac
     7801 gatcttatcc gttcctttga cgacaatccc gtagcctgct gggagatttt ccttttgatt
     7861 gcgattggga aggatatgcc ccagatagta aatctcatct tccaaggtct tgacgggcag
     7921 aaaacctgct gggtaggcga cctctggcaa actagcatag acatggatat cctcagcatc
     7981 cgccactgtg cggactcgta aaacgagacg ttctatttcg attttatctg gcagctcagt
     8041 tcttgccatc cttcttcctc gcttttttga tgaaactgcc cttcatatct acacgcttgt
     8101 ccagatagcg ataaacgcgc tgatatccat ctcccatgaa ataggttggg gcaaacagtt
     8161 gatttttaaa atgtcccttt tcatccagga gttctggggc aacaagtcgc tcaagaatct
     8221 tggcaaagat gtggcaaata ccgtcttcct caacaatcct atctacccga caatctaaaa
     8281 caagtggaca ggcgtctaaa ataggagtct gagttcgttc agaaatttca taatgcactc
     8341 ccaaacgttc caatttctcc tgatgactga taaaaccagt ctgctccatc gcaagcatag
     8401 aagtttcatc agaaatattc acagtaaatt tttgatactg tttgatctgc tctgcggcat
     8461 tctctctcgc aacgactcca atcacaaccc aatctcctag actacaagag gaactacatg
     8521 tcgtgatgtt atagccaaaa ttctaatctt gatatcctaa aataaaaaca ggaaaaccat
     8581 agtatagttt acttgtgtta aaagattgct tcataacaac cccctttgac taagacgtaa
     8641 aagaaaagcc ctgccatcta catgacaggg acgaatgtgt ttatccgcgg taccacccaa
     8701 tttcgggcca agcccgcatc tttagtcttt aaaataaaaa gacagaaata tttcattttt
     8761 tcagtcatta gcaaccagtt ttgacacatt tgtggacttc tcagcgccgc cactttctgt
     8821 aaaatgtggg attcaaaaca cctctaatgg ctctattgta gcaagttttt ctcggaaatg
     8881 caaggctcaa gaaaaattac ttgaacttga tgccattttc tttcaatttc ttaatggtag
     8941 ctgggccgat tcctttcaag gcaaggagtt ctttttcagt ccagtttttg aaatctgaag
     9001 cagaattgat tccttcatca tagaaagtct tggcacgatc aagtggaagt ccacccaagt
     9061 ttgctgcaaa atcttctaca gaattagcta ctttttgagc ttgctctttg gtagcttcta
     9121 ctgcttgttc aactttttta gaaacagcct taccagctgc gcttgctgac tgttctgcac
     9181 gcttcacgac tttttttgtc tcatctacaa ccttagtcac agtacttgaa aaggcacctg
     9241 cgcgacggag gccatttcgt aattgttttt tacgattgag tttctttgac atgataaaat
     9301 cctttcaata aaaaatccct gctctgacaa ggatttaaca taaacattct atcaagattt
     9361 tagtgaaaaa tcaagaatct ttctcgttta ataatttcgc tcaccaaaca agccttctgg
     9421 caaatcatgg aatcccttgc ctactttgaa gttttcaaac ttaccaagca agaactgata
     9481 agcatccaag cgactctcgt agcgaatcat ggcatctttg gcacgctcgt cctggtcttc
     9541 ttcgtaaact ttttggcttt ccttgtgcgc catgtcgtta atcatgattt gggtattgac
     9601 ccaagcttca aattccttca taaattcttg ttcgtaactc attttttctc cttattctaa
     9661 tccacgaaaa tagtccgtat caatctcacg gtagggctgg atatcctgaa cgtattccag
     9721 tacaccttgg aattctccgt tttcatcgtg tactgcagca taggtgatgt ggacaaactt
     9781 gcctcgcgac tcagacttga accacatttc atacttgtcc ttggtcccct cacgaagtcc
     9841 cttcatgata gccttgacct tgtccaaata cttaggcgga tgacagagtt cgacattgcg
     9901 cccgacttgg gacggcgtcc gtttgaaaat catctcatca gctggcgtat tgtcattgta
     9961 atactggaaa atatcttctt tattgacaaa ggtaatctcc atagggagat gattgaggat
    10021 gagattggcc tgctcgactg aaagatagcc attaccaaaa gcctgttgac tatggcggtc
    10081 cagcacagct tccttttcct taggggtaaa ggtaatggta aaatggcctt ctggcgtatc
    10141 tatgacttgt tgaacttgac cttctgccgt atctagctgt acaggctcct ctgcaatctt
    10201 ttcctcaata aagctctgtc gttctggcac ccatttctct gacggacgga tgatggcata
    10261 gccatagaca tcgctctcct ccgcaatctg aagccagtca tcctgagtaa aagactcaag
    10321 gagaatcatg aggaggatgg actcttcctt gaaaatcata ctttcaaact ctatcgcaaa
    10381 agcttcaaaa acttccttta cactgctaat tgacacttct ggtagtgact tggctgtcgt
    10441 tagagctgtt tgaaagagtt ccctaatctg atcatccact ccccacataa ctttgggagg
    10501 tgaatcgtgt ccatagcgct ccatgatagg aaagaagagt tcttctttac gttggtaatg
    10561 gatgtcaaat tgccccacaa gtcccatctg acgcaccaag cccttgcgca tctccgcaag
    10621 catttcctcg tcttccatca actcataggt atctaacaat ctacgaatgc gaatcaaagc
    10681 tgcacggagg gccaaatttt cttccttaaa gacacgaact gggtgacctg gatgctcagt
    10741 atctgaaact tcgacacctt tgatagcatt tttaaaaaga ttggcatgga catcacagag
    10801 ttccataaca tcttcaaagg tgacacctga gtctgagttc atcagctcgt gctccataag
    10861 ggaaatctca atggctgaga cacccgtaaa ggtcgcatca aagcgatctt gaaccgactc
    10921 aggagaggcg ccattgtgca attctaacaa aatatcccgt aggatatgaa tccgttcatc
    10981 tgtcattagt ctaatccaat cacttcgtag ccattcgctt ccagtgtgcg tacaatcttg
    11041 tccataggag ttcctgctag cttagaaccc tgtttaagtg atactttacg accaactgta
    11101 ttgcgcatta agggattggc aaggggttta aaacccaact ccactagaat ttccaagact
    11161 tctggatgct tgtccaccac ttctgcaaca ggaattgaca catcgatgat attgtccatg
    11221 acgacctcca ttgtatgttc taatactcaa tgaaaatcaa agagcaaact aggaagctag
    11281 ccgcaggttg ctcaaaacag tgctttgagg ttgtagatag aactgacgaa gtcagctcaa
    11341 aacaccgttt tgaggttgtg gatagaactg acgaagtcag taacatatat actgcaaggt
    11401 gaagctgacg tggtttgaag agattttcga agagtataaa atgattttac tgcttatatt
    11461 ataccatatg gagagagatt aaaaaactag cagtggagtt cctgctagtt ttctgcgact
    11521 tggattacca tctagataag tttaaagaac caatccaata tcttgtaaaa cagcaattga
    11581 actgcaaaag aaatgatcat ccaaaagaat ttcacaatcc caataatcgg tttgataaaa
    11641 agaatagcaa gaattgtcca gaaaaatttc attctctctc ctctggctta atgagccacc
    11701 gagccgtatc cattagctta tctgcaataa agagttttcc cagaccaaca acgacatggt
    11761 catctttctt tatcgttttc atcactttta caccttgcac ggtcaaaaag taattaccat
    11821 aaattttagc aaaagctttg ataggattca tattattctc ctttgatgat ttcagcctct
    11881 tttcggattg tttcaacatc ttcttgatat tgaacttcac tatagttgac tagcttggat
    11941 aattctttct gcaagctttc ccccattggt ttcatagttg caaaggttaa accacctgaa
    12001 atgataccac ccaagatagg aataaatttc cctattcctt tggccagccc tcccttggta
    12061 agattcacac caaatatttt taagactttt ttcaaaatag ggtaccaaag cgtctttgtt
    12121 aaagctttat taggcactgt tttcattacc tgtttggcaa ttgttatacc accagcacgt
    12181 agcaaagcag cggttccatt cacccctaac attacgccta gataaagcaa gagggtattt
    12241 tgagcatctt cacttaactc ctcacgtgaa gtccaaagag cctcataacc ataaatataa
    12301 cctaattctt gagccaattt cagagagaaa gcataaaatt gagccacatc agctggaatg
    12361 gtaattgcca tagcaagccc tccaggtaat cctgccaaaa cagaagtccc actcgctaat
    12421 aatacattgt cccgaataca agcattagct acacgatcta atatttcttg agatagaaga
    12481 gtcgttgtac cttgttccaa taaggtagga atatcttttg gatccaattc tttggaaaac
    12541 ttatccacta aaaatttcga acgatcaacc ttaacaacag gtagtttcac cacttgttgc
    12601 aatacttgca tagctaagtc ttgttcagcc atatacaaac tccttatttc ttttttacac
    12661 cttatcatat tatatttcct acaaaaaaag cattttctaa ttagataaca ttaaaaaata
    12721 cagaacccct tttttatagt aaaatgaaac aagaacagga caaatcgatc aggacagtca
    12781 aatcgatttc taacaatgtt ttagaagtag aggcgtacta ttctagtttc aatatatttt
    12841 aaaagaatat ttttccattt caaattcaac ctattttcct ccaccaaaaa agaggggcaa
    12901 cccctcttct ttagttctta tccagattgc gtagcatctc gtcaatcttg tttccatact
    12961 cgatggactc gtctttgacg aaggtcaaat ctgggatttt gtacaatttc aaattgcgac
    13021 caagttcacg tttgatggta ccagttgctt tttcaagccc gatttgggct ttttggttat
    13081 ccgaagcaag gttactcaaa atggtgtaat aaaccttggc aacagacaag tcacccagca
    13141 tctgaacatc tgtgatggtc acaccttgga cacgtggatc acggactttc ttttgcaaaa
    13201 tctcattgac ttcacgcttg atttccatgc ccacacgatc tgtacggaaa tgatttgcca
    13261 tgatattcct ttctctactt tgaaccaaaa gctaggccag cagacctagc tattttaaac
    13321 ttcttgattt tcagtttaaa ttgaaacgaa gttcaatttg aagtcatctg cttctttcgc
    13381 cgtggtgaaa gtgatggaac tgatttatca gtcccatcac aggggatttt tgagacccta
    13441 gactcaaaaa taagcaatga aaccatcggt ttgcttgcgt ccctcaccac ctaagaaagg
    13501 agcaaaaaat cttatctctt gatttcttcc atgacatacg cctcaatcac atcatccatc
    13561 ttaatatcat tgtagccgtc gatcatcaat ccaccttcac ggccgtttgt aacttcctta
    13621 acgtcgtctt tatagtgttt caagcttgcg agttcaccat catagataac gacaccatca
    13681 cggataacac ggactttaga gtcacgggca accttaccgt tgataaccat aaatccaccg
    13741 atagttccca ctttagacac cttgaaggtt tcacggataa ccgcttcacc aataactttt
    13801 tcttcaaatt ctggatcaag catccctttc atagcttctt ccatctcttc gataaccttg
    13861 tagataatgc tgtgaagacg gatttccaca tcgtcagctt ctgcttgttg acgagcttgt
    13921 ggtgtagggc gtacgttgaa accaacgata aaggcatttg aagcttcggc aagggtcaca
    13981 tctgattcgt tgatagcacc gaccgctgag tggacgatag tcactttgac accttccacg
    14041 tcaatctttt gaagtgaggc agaaagggct tcaacagaac cttgtacatc ggccttgatg
    14101 ataacattaa cagatttgag ttccccagct ttaagggtat caaagaggtt ttcaaggcta
    14161 acacgttggg tagcttgacg ttgtttcatt agggcacgtt tggcacgctc ttcacctgct
    14221 gcacgcgcag atttttcatc ctcgtaaacg gcaaagtggt cacccgccat cggtgcttcg
    14281 ttcaaacctg tgatagagac tggtgttgat ggtccagcaa ctttaacacg acgaccaagg
    14341 tcgttggtca tagcacggac acgaccgaag gtatttccga caacgattgg gtcttgaaca
    14401 ttcaaggtac cttgttgtac aagaagggtt gcgaccgcac cttttccttt atccaagcgc
    14461 gcttcgataa ccgtaccgat tgcacgcact gttgggtctg ccttgagttc ttggatttca
    14521 gctacaagaa ggactgtttc caacaattct tcgatatttt ggttgaattt agctgagatt
    14581 tcaacaaatt cagaatctcc accccaagcg gttgacataa ctccatgctc tgccaattca
    14641 ccgataacgc gttctgggtt agcacctggt ttatcaatct tgttaatggc tacgatgatt
    14701 ggaacgttgg ccgcttttga gtggttaatg gcttcgatag tctgaggcat aaccccgtca
    14761 tctgccgcta cgaccaagat cgtaatatcg gtaacagaag caccacgcgc acgcattgat
    14821 gtaaaggccg cgtgtcctgg tgtatcaagg aaggtaatct tcttaccatt ttccacgatt
    14881 tggtaggcac cgatatgctg agtaatacca cctgcttcac ctgtcgcaac acgtgagtta
    14941 cgaagagtat ccaaaagggt tgttttaccg tggtcaacgt gtcccatgat agtaacaact
    15001 ggtggacgct caaccaattc atcttcattg agataaccat cttcgacaaa gaaacgttcg
    15061 atgtcagcat tatccacttc aaccttttgt ttggcttcga taccgtaatc caccatgagg
    15121 agttcaattg tttccccatc caaggattgg ttttgtgtgg ccatgacacc catcatgaaa
    15181 agtttcttaa cgatttcagc tggttcacgt ttaatacgtt ttgcgatttc cgcaacggtc
    15241 ataccatctg tatattcaaa ttctgttggc aattcatgga atttacgctc cgtaacaggt
    15301 tttggagtct gattacggtt gttcttgtta ttgccttttt tgttcttttt gttgttattc
    15361 cagttactat tcttttgatt tctcacttga ttttgactac ttcgattctt ttgttgtttt
    15421 ctaggaccat cttcttcatg atcataatcg tcacgatttt tgtctggtcg agcttgtttt
    15481 ttacgacgtg tatccactgc aggttctttt ttctcaggga cgacttcaac cactgcttga
    15541 acttgctgtg cttgttcagc taacttagcc gcttcttcaa agatttcctc tggttccttg
    15601 cgtttgttag cttgagccaa ggcttcttta gcagcctgat actgcttgaa gcgttcctca
    15661 cttgaacgag cgtactctgc attttgctct gcttttaggg ctgctgcacg ggctttaaag
    15721 tcaatacgtg gagccgcttg atttgaacgt ttatcctctt gctgacggcg ctcatttcta
    15781 cgtttttgct gaccttgctg cttcttagct tggtcattaa agcgacgatt gtcgcggttg
    15841 ctttgacctt gttttccacc attacggccg tcgtttttct gacggtttcc gttttgttgt
    15901 tggtcacggt tattgccctt attttgcttg cgtcgttctg cctgctcttt agcacgggct
    15961 tcacgctcag ccttgaaatt acgactttgc ggtttcgctg ctactttttc tgttttcgga
    16021 gcaactggct cagccggttt tgcctcttcc ttagctacag ctggtttagc tggctcagat
    16081 ttttcggctt tcttttctgc acttactttt ggtgctgcag gttttgcttc tactttcgga
    16141 gcagctgcag gcttaaagct ggcagcaatt tttgcagcga cagcttcttc cacacttgat
    16201 gagtggcttt tcacatccaa gcccaactct tttgcacgcg ctacaacttc tttactttct
    16261 tttccaagtt cttttgcgat ttcgtacaat cttttcttag acaaatcatg tcctcctctt
    16321 ctattccata agagacctca ttttctttgt aaatccagca tctgttacag ccaaaacctt
    16381 tctcgatttc ccgactgcta tgcttaattc cagtgttgaa aacacggtta caatttctac
    16441 ttgataataa tgacttttat cttgaatctt cttggtcaga ttgggtccag catcatgagc
    16501 tagaaagacc aacttggcct tgccgtcttg aatggccttg accaccaatt cttcacccga
    16561 tatgatgcgc cctgctcgct gagcaagccc caagagatta cttatctttt gcttattcaa
    16621 gtcccaactc tcttcttttc actttgtgat ccacataagc gatcaactcg tcataaaagc
    16681 tttcttccac ttccatgcta aagctgcggt taaagacctt cttctttttc gcctctaggg
    16741 cttctgcatt gtctagtttg atataagcgc cgcggccatt ggccttgccc gtaggatcaa
    16801 taaagacttg tccttccttg ttcttgacaa tgcggagcaa atcacgctta tcaatcactt
    16861 cgttagacac aacagacttg cgcaaaggga tttttcttgt tttcatcttt ccctcctcta
    16921 gcagctttta ttcttctaca gtatcgtttt ctacttccaa ctctactgaa gcagcgtctt
    16981 ccatggcttc aaattcgcta gcagacttga tatcgatacg gtaaccagtc aagtgagccg
    17041 ccaagcgcac gttttgtcca cgacgaccaa tggcaagaga aagcttgtta tctggaacaa
    17101 ccaccaaggc acgtttgctg tcgttttcat caaagataac ttggtcaacc tcagcaggag
    17161 cgatggcatt gtagataaat tcagctggat ctgctaccca ctcgataaca tcgatatttt
    17221 cttcgattgg taccatgcgg tcatttttag catcgtaacg agctgggtgg aatttgctag
    17281 taatcttctt gatattagca ccaccacgtc caacgattgt accgatagca tccacgtttg
    17341 gattgtggct acgaacagca accttcgtac ggtcacctgc ttcacgagcc acgctcatga
    17401 tttcaacagt tccatcataa acttctggaa tttcttgctc catcaaacgt ttgatcattt
    17461 ctggatggct acggctaaca aagacgttca caccacgagg gttgtcttca accttgtaaa
    17521 cataaacttc gatacgatca tgagaagcaa aaacttctcc aggaatttgg tcttgttttg
    17581 acaattgggc ttcgatgcta ccaaggttga catagataaa gcggttgtca aagcgttcta
    17641 ctgtaccaga catgatttct tgctcatgtt ctttgtaagt attgtaagtg atggcacgtg
    17701 tttgcttgcg cattttttcc atgatggttt gtttggcaga ttgggctgct acacgaccaa
    17761 actcagctgg tgcttcttca aacttgattt tgtctccaag ttcataagct gaattaatgg
    17821 caagagcatc tttcaagctg atttccaaac ggctatcaaa tacttcatca acaacttcac
    17881 ggacagtata aactgtaaag tcacctgttt tttcgttgaa gtcaatagct acgctgtctg
    17941 actgaccata gcgtctgcga taagcggaac gaagcgactc tactactgcg tcgatgatat
    18001 cttctttttt gattcccttg tcttcttcca aaatgcggaa ggcctctagc atttctttac
    18061 tcatgttttc ttcacttttg aatcctcaaa agctatcctt tctttttcta taatttaact
    18121 gctaaacgtg cttttgatac taaactgtat ggaattcgga cggttttctt acgcgtcttg
    18181 tccatatatt ccatagtcaa ctcgtcctct tcgaaggcca acaaagttcc ttcaaagacc
    18241 ttttgcttat cgatggcttg gtagagtccg acatggatgt attttccaac cgctccagcg
    18301 acggcatcct tggttttcaa aggacgttcc aagcctggac tggtaatttc taggaaatat
    18361 tgttctggga agggatctgg cttgatggtg tctaggacag gactgataat ttctgtcaag
    18421 tctgccgtgt cgttcaaggt aattccttcg ggtttatcta caaaaatact gagaatcatg
    18481 tcactgccaa tctttccata ctcgatatcc acgagttcaa aaggagcttc tatgacaggt
    18541 tctacaactt ctctgactaa ttctacgatt gttgcgattg cgtccacctc ctcataagca
    18601 agaggcgaag atatttcccc gcctcacttt tcatattctt actatcagta tagcacgttt
    18661 gccaacttat gtaaagcaaa agcacttgta cagcctaatt ttaggctatc tcttaaaatt
    18721 ctgcctcaac tcggtagata acttgcccct tgtttgagaa tttttgctcg tattctgtca
    18781 tgacattgcc ttcaaaatca ctggcatgca aatctagcca gacaccattg agtttcatgc
    18841 catattgaga aaagctcact aaactgtact caaacaagcc acggttatcc gtcttgaaat
    18901 gaatttctcc attttcaggc aagatacgtt tgaaggtgtc caaaaaggtc ttgtaggtca
    18961 aacgacgctt ttcatggcgt tttttcggcc atggatctga aaagttcaga tacaagcgat
    19021 caatctcacc gtcttcaaag tagtcagtca agtcagaacc atctacccac aagagcttga
    19081 tgttaggcac tccaacttca agcaccttgt ccaaagcgta gctcaaaaca gacttttgaa
    19141 tatcaatccc gatatagttg atgtcagggt tttgcttggc catacctgaa acaaaggcac
    19201 cctttccact tccaacttcc acatgaatgg gattatcatt gccaaacaag tcccgccatt
    19261 ttgccttggc ttccaaggga ttgaggacca catactgggg atttgcctct agtaattctg
    19321 ttgccccttt acgatttcta actctcatct tctctttcca tacttgtctc ggaaatgacg
    19381 caaaccatga atctcccgat tgacattttc taaatcttgg ttcatataat acttggaaat
    19441 ctgactcaaa taagacaatt gaccatacca atacaattta cttaataccg tttgattgta
    19501 cttgtaaccg tagtaggtca accattcctt ccactgatgt tctgaaatat aatggcagag
    19561 catatgggcc acatcaaaca tgcgatcggt caagcgaacc gaatcccaat ctactaaata
    19621 aatcaagcca ctatctgtct caatccaatt actatgtcgt acatctccat ggacaatggt
    19681 cgcatggtcc tctctaaatc ctggaatagt ctgacgtaaa tcagccatca cttcactgat
    19741 aaaatgattt ttacgcaaag catctggagc cgtttcctgc caagactgta gtaaatctac
    19801 aggtgtttcc atggcatagc ccaaacgact caattgtgtc atcaacggac gtgagcgatg
    19861 aagacgggtt aaaatattga cgatttgctt acgattcata tcataggggg tcaatatctt
    19921 gcctgtcaac cattcttgag cacacatatc acgcccatct gccaaacgac gactccataa
    19981 taattgtgga gcaatttgtt ctctagctag accaggtagg attggagagg tgttcatttt
    20041 tacaaagatg cgcttcccat caggatagct acccatataa gccttgccac ttttcccagg
    20101 tatgggagtc agtgttagct cattatcacc caaatccatt tctttcctcc gtataaagtt
    20161 tccttactat tctactagtt tttggcctat tcgtcaacca ctctaacccg attctcaaag
    20221 aaaagcctct ggattggctt gggtatcatt atagcttgaa aaaggtaagc accgtcttct
    20281 gcttaccttt tcatcatttt tataaataat ataagagtgg ccaactgttg taaagcatat
    20341 ggactagagt agaaacccat aggttttgac tctttttata agcaaagccc agcaacaaac
    20401 ccccaagtag ataaaaaata aacgaaggga cattagaagg tccatgcatg aaagaaaaga
    20461 gagaggaagt tagcacaagc cctaaccaag aattgtcaaa aaccgcacct tgaagaagtc
    20521 ctctgaaaat gagttcctcc tggatggggc caaaaactga ggtagttaaa atcaaagaca
    20581 gggaaattcc tctgctgact tccgccaagt gttggacccc tgagccagaa gaaacagcga
    20641 agaaatgaat ataaaccagc gtctcaagta cacttagaag aaagattgca atgaaaagca
    20701 aaagttgttt cttgcttaac atcccaaaag aaatcatttc aaactttcta gcataagcaa
    20761 cactcagcga ggttacaaga agacttacaa gaatcaatgc agattcattt tgaaaaaaaa
    20821 acccatggtt aatcgtataa ggaactgtaa tgacaattat tagtactaaa aatccaaaac
    20881 acaaggcatg aaatttatca aaaaactcca taaaattatc ctcctcaaca aacagacttc
    20941 ctacacgtca ttctttagtt ctagcctttc caaaacaaac cattttatac tcttcgaaaa
    21001 tcaaattcaa accacgtcaa cgtcgccttg ccgtactcaa gtacagcctg cggctagttt
    21061 cctagtttgc tctttgattt tcattgagta ttagtaacca aaatccgacc acatagccag
    21121 cccctatgaa tatagccatt aaagctagca tggaatttag gaaattaaag atcaccgcag
    21181 acacaaaggt tagcacaaaa acattaaagg caatggtgtc agaagccaag actagaatat
    21241 agggcgtcaa ccagtctaag gttttggaat ctaggaaaaa taagtgttta tacatgataa
    21301 tctcctctat ggctgaaaag caagcctttt gtttttttac cccaagaccc tatgtaaaaa
    21361 agtcagcaaa aatggtaatg ttgcgaaaat attattgatc acatgcaccg cataggaagg
    21421 ataaatgctc ttggtatagc gggtcaaacc agcaaagatg atgccagatg ttgcaaagat
    21481 gaagatatct aacaaactag gcaggcttga aaaatgagga agagcaaata aaattgacgg
    21541 aagaagcaaa tcaaggccaa atctcgaatg cttaaaaaag gcgtgttgca gtaatcctct
    21601 atagattagc tcttccataa gtggagtcag aaagaacaaa gttatataga tacctagctc
    21661 agcaaagttg gtcccactat aaccgatcaa tacagcccaa ccttcagcag ttgactgaac
    21721 atgtttagct gtctgaacgt taaaagagat ctggagcact accactaata ctgtcaaaat
    21781 cgaataccaa agccattttt ttcttggaat gtgaaagaga taaccatgac ctgtcttaac
    21841 cagaatccaa atcatgactc cgctaaatag caaactcaag aaattttgaa tccagacgaa
    21901 attgccaatc tgggaagaaa attgccaata attttggacg ataagcgtca tctgagaaag
    21961 accaaatacg aaaaataagt cagagaaaac tgcacttatt ttgaatagaa gttgatactt
    22021 tttcatagaa attcttccta ctatgacctc accttgtcag gctctactgc tgtaagatta
    22081 agaagacagt ttgttctttt taaggctaac ctgactacta gataatagat acattaaggc
    22141 attaaagaca atgaaaatat gtccatagaa taaaatcaac ctcgcatcca aaccaagata
    22201 aagtttgatt atcaaaaaga tgagcaaaag aatttgaaac cataaggttt ttccaaaaat
    22261 aaatttaaag cgatttcgaa tatctacttc cttgattttt accgccaccc ctttattagc
    22321 aagaaggaaa actcctgctt caaacaaacc actgtaaaga acaagccacc caatagatac
    22381 gatagagatt tgtaaaaatg tccctaaaag aatatccaac acactactca agaaaataac
    22441 aaaaaataat ctgtatttca tattaaatac ctccattcat ttatttcact aacaatttaa
    22501 tagagccttc tactcaaata tcctgtcaga aaaggataga aagctacttt ttataatact
    22561 tcaagcccca catgagcaga agcgtgataa acaagcagag aatacaccta tataagcgat
    22621 tagttgttga tagaattctg tttctgaaat acctctatac aaacaaatga caaacataaa
    22681 atctgccaag ccgataaaca taagttgatt ggttctagga ctaaccaaat catcatttac
    22741 ttatatttaa gagtatctct tttatgttaa tgtatgttag cactgaaaag caagacaggc
    22801 caataatatt taaaatgaac agtaacgggg ttaagtctct aaaaaaatta tctactgaca
    22861 ctacaagaaa tactatacat attatagtcg aaactatctt tttcttatcc ataattattt
    22921 actcctttcc taacaaatcc agcttatcaa tcaagagcga tttttaacat aatgtagcag
    22981 cacccgttgc aactttgaca agtttagtat atcattgttt tttaaaattt ttcatccaaa
    23041 tcttgaattg tcatcgaaac atcttgaatt gttaaaaaat ttaaaaagta agcat
//
LOCUS       DAVDHC010000034        23006 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVDHC010000034 DAVDHC010000000
VERSION     DAVDHC010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23006
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.034"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(104..274)
                     /locus_tag="VUR43_001785"
                     /pseudo
     CDS             complement(104..274)
                     /locus_tag="VUR43_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(581..1015)
                     /locus_tag="VUR43_001786"
                     /pseudo
     CDS             complement(581..1015)
                     /locus_tag="VUR43_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1257..2141)
                     /locus_tag="VUR43_001787"
     CDS             complement(1257..2141)
                     /locus_tag="VUR43_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET5413435.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(2145..2531)
                     /locus_tag="VUR43_001788"
     CDS             complement(2145..2531)
                     /locus_tag="VUR43_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET5413436.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(2524..3867)
                     /locus_tag="VUR43_001789"
     CDS             complement(2524..3867)
                     /locus_tag="VUR43_001789"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET5413437.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLDLGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMTKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLAAQGIKLLDTKDGVRWTRD"
     gene            complement(3949..4833)
                     /locus_tag="VUR43_001790"
     CDS             complement(3949..4833)
                     /locus_tag="VUR43_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5413438.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRTYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRSYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(4845..5462)
                     /gene="cysE"
                     /locus_tag="VUR43_001791"
     CDS             complement(4845..5462)
                     /gene="cysE"
                     /locus_tag="VUR43_001791"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET5413439.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(5478..7691)
                     /gene="pnp"
                     /locus_tag="VUR43_001792"
     CDS             complement(5478..7691)
                     /gene="pnp"
                     /locus_tag="VUR43_001792"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET5413440.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(8376..9242)
                     /gene="metF"
                     /locus_tag="VUR43_001793"
     CDS             complement(8376..9242)
                     /gene="metF"
                     /locus_tag="VUR43_001793"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET5413441.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNEHFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(9306..11555)
                     /gene="metE"
                     /locus_tag="VUR43_001794"
     CDS             complement(9306..11555)
                     /gene="metE"
                     /locus_tag="VUR43_001794"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET5413442.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLDTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSFVAAYQEVFAKLADLGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLFQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            complement(11816..12082)
                     /locus_tag="VUR43_001795"
     CDS             complement(11816..12082)
                     /locus_tag="VUR43_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5413443.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAVVRLEQGKS"
     gene            complement(12208..12655)
                     /locus_tag="VUR43_001796"
                     /pseudo
     CDS             complement(12208..12655)
                     /locus_tag="VUR43_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            12811..13812
                     /locus_tag="VUR43_001797"
     CDS             12811..13812
                     /locus_tag="VUR43_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET5413444.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPALMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            complement(13880..16285)
                     /locus_tag="VUR43_001798"
     CDS             complement(13880..16285)
                     /locus_tag="VUR43_001798"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET5413445.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VRVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(16362..16871)
                     /locus_tag="VUR43_001799"
     CDS             complement(16362..16871)
                     /locus_tag="VUR43_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5413446.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            complement(16871..17917)
                     /gene="pheS"
                     /locus_tag="VUR43_001800"
     CDS             complement(16871..17917)
                     /gene="pheS"
                     /locus_tag="VUR43_001800"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET5413447.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            complement(18399..19814)
                     /locus_tag="VUR43_001801"
     CDS             complement(18399..19814)
                     /locus_tag="VUR43_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET5413448.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDITLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWVDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            complement(19827..21665)
                     /locus_tag="VUR43_001802"
     CDS             complement(19827..21665)
                     /locus_tag="VUR43_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET5413449.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(21683..22522)
                     /locus_tag="VUR43_001803"
     CDS             complement(21683..22522)
                     /locus_tag="VUR43_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET5413450.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(22822..23004)
                     /locus_tag="VUR43_001804"
     CDS             complement(22822..23004)
                     /locus_tag="VUR43_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET5413451.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
BASE COUNT         6689 a         5060 c         4126 g         7131 t
ORIGIN      
        1 tagtagattg aaactagaat aatatacctc tacttctaaa atattgttag aaatcgattt
       61 gacttccctg atcgattcgt cctattctta tttcatttta ctataattga tagtggtcgc
      121 cccagccaga taccttatct gctatccatt taggaacccc taacttaagc aatccccata
      181 atcgtctcga tttcttcttc cattgcttcc agataatcac tcgtaggcga gtacgcaagc
      241 gctcatctat gctggcgact atacttttca tattttaatt cattcctttc gtttcactca
      301 aggcacaaca cagaatgaaa aagtgttgtg ctctttattt tgttttataa taatagtgag
      361 aaagcctatc actactacaa atcacgggga ggtgaataag tgagtggtac agccactacc
      421 tcgcatattt tgtcacatca tttaacggta cataataagt tgtaccatct gaataagttg
      481 ctacaatatc atttgcatgc tctccttcac ctttagcaaa ggttggagct cctgctggat
      541 gatttttatt tgcctctttc aatttttcaa taatggcatt tttttctgta tcttttatat
      601 tatcaggatt tttcactaag attttgtctg gatatgtcgg tttagcagaa acaattttta
      661 ctgttacttc ttttttattc gaagcacttg tccagtttcc agcattatct ttagcattta
      721 attttacagt aattcctgaa ctaggaactt cagtagcagg ttgattatta acattattca
      781 actttaattt caaaagagct gttgcatcag acgttttatc aatcgttata tataatgatg
      841 aattgttatt ataaccagtt tcttcatatt tagctgtttg tgagctactt gaaacagaac
      901 tgaaattata cccactacct ccctgattat cttcaatgct tacatctaaa tgaacttccc
      961 cactattatt tggattagca acaactgtta tagtaaaata acataaaatt cacataaata
     1021 gattagggaa atcaaagcaa cttctaggaa tgttttatac tcttcgaaaa tctcttcaaa
     1081 ccacgtcagc ttcaccttga cgtactcaag tacagcctgc ggctagcttc ctagtttgta
     1141 ctttgatttt cattgagtat tatcagtcac agtgtacttt cccagcatca agccactata
     1201 actctgcaca taaaaatgga gaagatggca atcctcttct ccaaatatta acttctttac
     1261 aaaccaacta tagttgacaa agaacctaaa atcaattgat aacacaaggt caggtcggtc
     1321 aactctttca actgaagccc tgtcaactct tcccatttat caatcttgta ttggagagaa
     1381 ttgcggtgca gatagagttg ctgggctgtt ttagtgagaa cagcactatt ttcccaaaga
     1441 gagagaatga tttcctgaat ctgatcttga tccaaaatca tctggtgtag acattcttta
     1501 attggcttca agtccacgag tctttctccc atactccaaa gatagagctg agaaaaagta
     1561 tgaacacctt ggtgaccctg acgccaccat gtcttgaaca aatcccgctc agctttgatt
     1621 aagtctgata gggcttgatg tcctgtctga gaccaaacct gacccaacat gatagaaaga
     1681 cgaagtccaa aatcatactc aaccgcttca atcgtatcac ttaaaatatc tcttacagaa
     1741 gtgtatttgt cttgttgaag cacgaaaaca taatcctgag ctccgacctg tagcactgtc
     1801 tgacaattcg gaaaaagagt ccgcatcata tctagccaag aagtcagatt ttcctgctga
     1861 aaataagaaa gatggcaata aaccaactga atctttttaa aaacttgcgg tgcctgtccc
     1921 ttgccttcaa ccagatagga ataccaaggg tttagcgaac gagcctgctc ctgctgggtc
     1981 aaaagggcaa ccaactgctt ttcacgctcg ctgagcccag cttcctccag caaaatccac
     2041 tgctgagaag ctaaagggag cgtgagatag ccctctttct ctactggttg gtctgaaatc
     2101 cgagcctcag gaaaccagtc ttgtagttct ttttccctca tgttctagcc ctccactttt
     2161 tggatgcacc atgaaaccaa actctcaaga cgttccagat tctcagtcat atggagatag
     2221 cccataaccg cttcaaatcc cgtggacata cgataagtca cgacatctgc atttttagcc
     2281 tttgtgtggc tattggtatt gcggccacgt ttgtagattt cttcttcttt ttccgttagg
     2341 acctgctcct ccaacatgag agcaatcagg cgagcctgag ccttggctga cacatacttg
     2401 gttgcttctt gatggagttt attgggtttg gtcatacctt tgaggatgag gtggcggcga
     2461 atatacatag aatacaccgc atctccctca aaggctagcg caatcccgtt aatgagattg
     2521 acatcaatca cgtgtccacc tcactccatc ttttgtatcc aatagtttaa tgccttgagc
     2581 agccagttgg tcacggattt ggtctgctgt ctcaaagtct cgattggcac gcgcctcttg
     2641 gcgtttttga atcaagtctt caatctctgc atccaaaact tcctcaacaa agacaattcc
     2701 aaaaatttct aacatatctg caagagcttg cttgacactt gcatcatagt tccctgagtt
     2761 gatccatttg gtcatttcaa agacaactgt gataccgttg gcagcattaa aatcttcatc
     2821 catagctgct acaaacttat ctttaaagtt ttgtaactct tgggcatcca cgtttcctgt
     2881 aaatggttgt tcgtaagtat tcttcagata cttgagattg gtctcggcat cgcgaactgc
     2941 cttttccgtg aagttgatag gcttacggta gtgctgggtc gcaaagaaga aacgaagtac
     3001 ttgcccatca agagttttaa gggcatcgtg taccgtaatg aagttaccca aggacttaga
     3061 cattttgaca ttgtcgatat tgacaaagcc attgtgcatc cagtagttag caaaagcctt
     3121 gcctgtttta gcttcagatt gggcaatttc attggtgtgg tgcggaaatt ctaggtcagc
     3181 tccaccaccg tggatatcaa tggtatcacc taaaatctct gtcgacatga ctgaacactc
     3241 aatgtgccaa cccggacgtc caggtcccca aggactatcc caagaaatct cacctggttt
     3301 ggaagatttc catagagcaa aatctacagg attttcctta cgagccgttt cttcatcggt
     3361 acgacctgaa gcacctagat ccaaatcttc caaggtttta ttagccaatt tggcatagtt
     3421 gtgggatttt tctacacgga aatagacatc cccttgactc tcataggcaa agcctttctc
     3481 gatcaagtct tccacaaaac ggatgatgtc tgccataaac tccactacac gcggatggcg
     3541 agtcgcaggt ttcacgccta aggccgtcac atcctcacga aaggcagcga tgtacttatc
     3601 cgcaacctcc tgaggcgtga tgccttcttc cctggcacgg ttgataatct tatcatccac
     3661 atctgtaaaa ttggaaatat aggcaacctt atacccacgg tactcaaaat agcgacgaat
     3721 cgtatcaaaa gctaccgtcg aacgggcgtt tcccacgtgg atatagttgt acaccgttgg
     3781 cccacaaaca tacatcttga tcttgccgtc ctcaatcggg acaaattctc gcaaatcacg
     3841 agacatggtg tcatagattt taatcataaa tcataatcag gaaagctgaa atccaagaac
     3901 aattagtttc atcactaaaa gttcaagtaa atttcagtcc gaatatctct acacttcgga
     3961 atcccttgct cctttctcat tcagataaac cacctgagtc tgtttgacaa agccaatttt
     4021 ttcatacaaa cgtttggcac ctacattgct atcttccact gcaatctgaa attccttgtc
     4081 attttgctca attagttggt tgacgaggga ttttgctaag tagcttccat agccttttcc
     4141 acgttcaggt tccaatattg ctaaaccgta gaagtaattc gtattagtcg ataaatcaac
     4201 cgtacaagtc ccaataacct gaccgtcttt taacaaaata tatgagcgac tttctggatc
     4261 cttcagagct tcagcgacat atctatccac aacttctctc gattcatgtt cctctgaaaa
     4321 tgcctgaaat tttaattgac taatttgatc ctgatacgaa ctatctgcta acaaaacttc
     4381 aagatgggaa acatttgcta acggataagt tcttctatcc ttacctaacc aagtttctgt
     4441 ctcttcatcc tctattagtc cccagttact ggcaaagtca ggatgattct ctaaaaaaat
     4501 acgttctgtc tgaaaagtga ctgaccgaat ggggaaagaa gctgtttctc tctcaaaact
     4561 agtaaacaat gcacgcgcaa tcccctgacg gcgatgacct ggatgaacca gtatcgtcac
     4621 ttctacatct tggtcatctg catagacagt taataaacca acaagttcgc ctttttcata
     4681 ataaaggaaa aaggcgggca tgtttggatc aaaattaagc atgttagaga gatagggatc
     4741 gcgataggta ccgtcatagt tttggcaaca gttaattact tttttcgcct cagatagctc
     4801 ttcttggctt aacttgtttc ttgcttgaat catataggta tcctctacaa accagacgat
     4861 ctgtgactgg catctttagc ctgctcgagt ttattgacat aatactcccg tttttcttcg
     4921 acttcgtgaa taacaggctc atctttctta ccatgaagac ggacaatctt ggccggaata
     4981 ccgacaaccg tcacatcact aggtacatct gctacgacaa ctgctgcagc accgaccttg
     5041 gcattttcac caatttccac aggcccgata acttgggcat gggctgatat gagggctccc
     5101 tttcgtacag tcggatggcg tttgccacag tctttccctg ttcccccgag agtcactccg
     5161 tgatagagaa gaacgccttt ttcaacaatc gctgtctctc caatcaccag accagaacca
     5221 tggtcaataa agacacctga atcaatctgg gctcctggat gaatctcaat ctgagtccaa
     5281 aagcgccaaa actgactgtg catacgagct aagagtttga agtcgtactt ccagagaaaa
     5341 tgcgagagac ggtgggccgc caaggccttg acacctggat aagtcagcaa aacctccaaa
     5401 gtggtgcggg ccgctggatc attttctttt acgatatcaa tggtttcgcg ccaccacccc
     5461 atacatttct ccttttctta ctctgaatct tttggtgttt ctgtaaattc tttcttaggt
     5521 ttgtgatcct tgtgatgacg tgggcggtga gggcgctcag acttttcacc tttttcatca
     5581 tgctcaggtt ttggcggacg aggtagaaga gccttcatag aggcatcgat acggcctttt
     5641 tcatcaatct tgataacctt aacatcaact tcatccccga tttctaccaa atcctctaca
     5701 cgattggtac gagtccaagc catctcagag atatgaacaa gggcatctgt cttatcaaag
     5761 aggttaacaa aggcaccaaa tttctcgata cgaacgactt tagcacggta aacttcatcc
     5821 actttggctt cacgaaccaa accagcaata atttctttgg cacggttaat agcatcttgg
     5881 tcactagagt agatagacac atttccttct tcgtctatat caatcttaac acctgtttca
     5941 gcaataatct tgtcgatggt ttctccaccc ttaccgatga caatcttaat cttgtccaca
     6001 tcaatcttga tcgtatcaat tttcggagca gttggagcca attctggacg aacttctgga
     6061 atggttgctt caatgacatc aagaatttca aaacgcgctt tcttggcttg agcaagagcc
     6121 tccgtcaaga tttctgcagt aatcccttga atcttgatat ccatttgaag ggctgtaatc
     6181 ccatcacgag tacctgcaac cttgaagtcc atatctccaa agtgatcttc caaaccttgg
     6241 atatctgtca atactgtgta gttatttcca tctgagataa gtcccatagc aataccagct
     6301 actggcgcct tgattggcac accaccagcc ataagggcaa gagttcccgc acagatagaa
     6361 gcttgagatg aagaaccgtt tgattccaaa acttctgcta ctagacggat agcgtatggg
     6421 aattcttcca agcttggcaa gacttgagca agagcacgct caccaagagc accgtgaccg
     6481 atttcacgac gacctggcgc accgtaacga cctgtttccc ctacagaata ttgagggaag
     6541 ttatagtggt gcataaagcg tttcttgtac tctggatcca aaccatcaat gatttgagtt
     6601 tctcccatcg gagccaaggt caagactgaa agagcttgag tttgcccacg agtaaagaga
     6661 cctgaaccat gtacacgagg aaggaagtca acaaccgcat ccaaaggacg gatttcatcg
     6721 accttacgac catcaggacg caccttgtct tctgtaatta aacgtcgcac ttctgcgtgt
     6781 tccatttgtt ccaagatttc agccacatca cgcataatac ggtcaaattc ttcgtggtcc
     6841 gcatattttt cttcgtaaac ggcagtcact tggtctttca ctgcttgagt tgcagcttca
     6901 cgggccaatt tctcttctac ttgaactgcc ttttggaggt cactgttgta ggctgcaatg
     6961 atttcagctt gcaattcagc atccacgtga agcaattcca cttctgcttt ttctttaccg
     7021 acagcagcaa cgatttcttc ttggaaggca atcaattctt tgacagcttc gtgcccttta
     7081 agaagcgctt ccaacatgat ttcttctgac aattctttgg caccagactc taccatgttg
     7141 atagcgtgct tggttccagc tactgtcaat tcaagaagag attgctctgc ttgttcttga
     7201 cttgggttga tgatgatttg gccatctaca tatcccactt gtaccccagc aattggtccg
     7261 tcaaatggaa tatctgaaat agacagtgcc aaagatgaac caaacatagc agccattggt
     7321 gcagatgcat tttcatcata agaaagcact gtattgatga cttggacttc attacggaaa
     7381 ccttccgcaa acataggacg aatcggacgg tcaatcaaac gcgctgtcaa ggtcgcatct
     7441 gttgaaggac gtccttcacg tttcataaag ccaccaggaa acttcccagc cgcatacatt
     7501 ttttcttcgt agttgacttg gagtgggaag aaatccccag ttgccatttt cttagacata
     7561 acggcagcag tcaagacagt tgactcaccg taacgtacga caacagatcc atttgcttgc
     7621 ttagcaacct gaccagtctc tacaattaac tcacgacccg caaaagtcgt ttgaaacact
     7681 tgttttgcca ttttaatccc ctttgggttg atgaaattat acgccttgcc tacaaagatc
     7741 aagataccaa ggacgtcaaa agcaaagtaa aaataggaaa ctgacgaagt cttcgatgaa
     7801 gacaagacag tttatctttt ttacacagct tttcggccgt gttcaattac acaagatatt
     7861 ttggacggtt cggcttgccg aacatttctg tagaaaaata ggaaggtgac gtcgcactcg
     7921 acgagtgcta ggaagcttat cttttttcct aagaaatgag accaaaattc aagtcatcaa
     7981 gataccaagc cgtcaagcaa ctcaaaggaa gataggaaat cgaacgacgg agcgactgct
     8041 cctagggaga tttatctttt tccacagagt tgtaggcaag ttcagttttc aagatacatc
     8101 attagaaagg tttaatatta aagtatctaa acctttcacg ctaattgcta tcgggcgatt
     8161 agctaaatgc tttactaact ctttcgtcaa ataacatcga tttgactcac tcgtgtcgtt
     8221 aaatcttaca gtttaaatgc attgtattat ttaatacctt catctttgta tcaagtacgt
     8281 acagaatcta ttttatcata tttttcttaa aaagtgaggt ctttgccatt aaaaaggaac
     8341 cattcccctc acctgagaag aatggtttgc ttttattatc ctagagactg gtgattaaac
     8401 aaggcatggg ttgcttgatg gatgtatttt gctgtatcag cattattcat cgtatagaga
     8461 tgcacaccgg caacatcctg agttaccaag tccacgattt ggtccactgc ataggcaagt
     8521 cctgctgctc tgagcgactc agggtcatgc tcatacttgt ctaagatggc tttaaatttg
     8581 cgtggaagat ggatattctc acaagtcttc aagagtcgga gagcctgatt tcgattcaga
     8641 attggcataa ttcctgcatg aatgggaaca tcaatcccag ccaagatgca cttgtcctga
     8701 aaatcataga agtgctcatt gtcaaagaag agctgagtta cgaggctcga acagcctgca
     8761 tccactttct tcttaagatt ttgaatatct gaaatctgat ttggcgaatc tggatgccct
     8821 tctggatagc aagctccaat aatatcaaag tgaggggctt gttccttgat aagctcaatc
     8881 aagtcggttg catagcggaa atccttttgt ggttccacgt ctggaataat atccccacga
     8941 agagccaaga ttttctgcac cccaactttg tccaagtcag caatagtttc agcaaccttg
     9001 tccttagtta gataaatagc tggcaagtgg gcaatggtcg gaatcgccaa atcattttgg
     9061 ataaagtcag ccaaacgaac cgtcgtttcc ttgatattaa atttattatt gctggcagtt
     9121 acactgataa aatggggagc caactcctgc atatcctgca aggctgaaat aatgttacca
     9181 ttacccacgg ctgggtttgg agggaacact tcaaatgaga gtgacggtgt ttggcgtgac
     9241 atatgtaata accttttcta gttgatttct ttttgaacaa ccactgtatg gagagaaatc
     9301 caatcttaca atttctcacg cgcagcttta gctgcttcaa caaggcggat caagctttct
     9361 tttgtttctg ggataccacg tgttttcaaa ccacagtcag ggttgatcca aactttcttg
     9421 cttggcactt tagcaaggat ggcttcgatt gtgttgtcga tttcgccttc atttggtaca
     9481 cgaggtgagt ggatatcgta aaccccaggt cccacttctg tttggaagtt tttcgctttg
     9541 agttcgtcca agatttcaag gtttgaacgg ctagcttcaa aggaaataac gtctgcatcc
     9601 atgttatcga tagctgggat gatatctgta aattctgagt aacacatgtg agtgtggatt
     9661 tgtgtgtctg gcgctactgt tgagtgtacc aagcggaagg caggaatagc ccagtcaagg
     9721 tagtcttcgt accagtcgct acggcggagt ggcaattttt cacgaagagc agcctcgtcg
     9781 atttggatga ttttcacacc agcagcttca aggtcaagta cttcatcctt gatagcaagg
     9841 gcgatttgga gagttgaatc cttgatagag atgtcttcac gtgggaatga ccagttaagg
     9901 atggtaacag gtccagtcaa cataccttta acaggtttgt ttgtacgact ttgtgcatag
     9961 ctagaccatt taacagtgat agggttaaga cgagtgacat caccccagat gattggtggt
    10021 tttaccccac gcataccgta tgattgtacc catccatttt tagagaagag gtatcctgac
    10081 aagttttgac cgaagtactc aaccatgtca ttacgctcaa attcaccgtg aacaaggaca
    10141 tcaaagtcaa tatcttcttg ccacttgatc cattcgtcaa tcgtttcagc aaggaaagcg
    10201 tcgtactctt tttgagacaa ttcaccttta cggtaagcca aacgtttggc acgaacttct
    10261 tttgtttgag ggaatgaacc aatcgttgtt gttggaagag ctggaagttt gaaagcttct
    10321 tcttggatag cttcacgttc tgcaaaggct ggcaaacgag tgtagtctgc gtctgtcaag
    10381 ccagcgatac gcgcacgaag ttcagcattt tcaccaacac gctcagtcgc aaagagttct
    10441 ttgttggctg caagagcttc tgaaccttga ccattgcgga tagcatccaa gtcacggatt
    10501 tcatccaatt tttcaactgc aaaggcaaag tggttcaaga gtgctggttc aaattcttca
    10561 ttagcagttg taaatggcac atgaagaagt gagcaagagc ttgtcaaaac gatgttttca
    10621 gctgggattt gctcaagaac agccaagctc ttttcgtagt tgttgcgcca gatgttttta
    10681 ccattgacaa tacctgcata gagagtcttg tcagctggga agccaccttt aacgagttca
    10741 agagttttct taccttcaac aaagtcaaga ccgatagcat ctactggcaa gtttacaagg
    10801 tcagcgtata cgtcacgaac atcaccgaaa taagtttgaa acaagacttc aagacctttt
    10861 ttgtcagcca agagtttgtt gtaaaggttc aagaagagag ctttttcttc agctgtcaag
    10921 tcttttacaa gagccgcttc atccaattgg atgcgagtcg caccaaggtc agccaattta
    10981 gcaaaaactt cttggtaagc agccacaaag ctatctacga agtcgtctgc tttcacgcct
    11041 tcttcaaagt ctgacaattg aaggaaagtg aatggaccta caagaacagg acgagtgtcc
    11101 aatccaagtt cttttgcttc ttggaactca tcgaaaatct tgtgaccagc caattttact
    11161 tgagtgtctt tttcaaattt aggaacgatg tagtggtagt tagtgttgaa ccatttcttc
    11221 attggaaggg cgcgaacgtc ccctttttct ccctggtaac cacgtcccaa agcgaagtag
    11281 cgctcaaggt cagacaagtc caagttttga acggatgcag gcaccacgtt gaaaaggaaa
    11341 gccgcatcta ggaagttatc atagtgagaa aagtcatttg atggaatttc agtgatgcct
    11401 ttttctttga caatgttcca gtgtttagca cgcaagtctt ttgctgctgc taaaagttct
    11461 tcttctgaga tttcttttct aaagtatttt tcagttgtaa attttaattc acggaattcg
    11521 cccaaacgag ggaaaccgat gattgtagtt gacatgatgt gtcctccaaa atttgttgtt
    11581 gaaactatct taacagaaaa gaaagcgtct gtataattgt aaaaaattag ggtttgatat
    11641 agtttgaaac tatatatctg tttcggacaa aagaaaaaga cttgaagcaa acgtctcaaa
    11701 tcctttgtat agcttgtttt atagctttat ttcagttaga cggttcaaac gcgttattag
    11761 taattcttat aagtgactat ggcttgttat tagaaaagac tataactgat tctagtcaac
    11821 tttttccctg ttcaagtcgg acgactgcta gtgtctttcc taaactggct aggactttta
    11881 agactgtatc caactgagga ctagtctttc ctgtctccat cctagctatg acaggctggc
    11941 ttattccact gacttcttcc agctttttct gactgattcc ttgttcatac ctagcctcaa
    12001 tcaactcgct catgatagcc actcgcatat cactttcaag gatttcctcc ttgctaaaga
    12061 gctcagatgg acatccttcc aattactccc aatagcacta ttcttcatca cttaaccctc
    12121 tttcttttac gtctatgtat ttttaaaaaa atgagcgaat tatgattcga tagattgacc
    12181 agcgggttta aagttggtgc tagcctattt cttaagcgat tttccttttc taggataaag
    12241 cagatcctgc ttgcttaacc ccaattttcc acgatgaatc caatagtaaa tggttgaaat
    12301 tcccacgtta acccctttag ccatcaccat catttcaggc gaaaattttt ggttatgtat
    12361 agtggagaat cttttccttt agttccttgg tcaagcttga tttcttgacc gagcgcttgc
    12421 gattgttttc ataagactgt tgagcgtagt cggcagaata aacctctttg aagcgccctt
    12481 ttccaagaca ttttcggact gtcccacgct tgatttcagt gtggatagtt tgaggagctt
    12541 ttccaagtag agaggcaact tctctatttg attttccttc ttttttccat ctttcgatta
    12601 agcgacggct atcgattgtc aaatgtttac cttttgtagt ataattgtct tgcatctctg
    12661 tgccttttaa tcatttcaat cttaaattgg acttttttta cttgggttgt acttaatcta
    12721 taaggaagac aagaaaaaga atatcaatca agtaaagtca caaagtcaca ttagctccga
    12781 gcaaccattg caaattgagg tactcacaca atgattaaaa catttctctc tgccctttcg
    12841 gtcattctct ttgttatccc tatcataact tattcttttt ttccatcttc taatcttaat
    12901 atttggctat ctaccagacc tatcttggca cagatttatg ccttcccctt agctactgca
    12961 actatggctg ccattttaag tttcgtattt ttttccctat ctttttacaa gaaaaataaa
    13021 caaatacggt tttactctgg cattttgctc ttattatcgc tcatattact attattcgga
    13081 acagataaaa ccctttcttc cgcttcaaat aagactaaaa ccttaaaatt agtaacttgg
    13141 aacgtcgcta atcaaataga agcacaacat attgagcgaa tttttagcca ttttgacgcc
    13201 gatatggcta tattccctga actagctacc aatatcagag gtgagcaaga aaaccagaga
    13261 atcaaactat tgtttcatca agttggactt tctatggcca actatgatat tttcacttct
    13321 ccacctacca atagtggaat agctcctgtg actgtgattg tcaagaaaag ttatggtttc
    13381 tatacagaag ctaaaacttt tcatacaaca cggttcggga caattgtatt acattcgaga
    13441 aaacaaaata taccagatat cattgccttg catactgctc ctcctctgcc agctttaatg
    13501 gaaatctgga agcaagactt aaacatcatt cataatcaat tggcttcaaa atatccaaag
    13561 gctattattg caggtgattt taatgcaact atgcgtcatg gagcacttgc aaaaataagc
    13621 tctcataggg acgcattaaa tgtactgcca ccttttgaaa gaggaacttg gaatagccaa
    13681 agtccaaaac tttttaatgc aacaatagat catattttat tgcctaaaaa ccactactat
    13741 gttaaagatt tagacattgt aagttttcaa aactctgatc atagatgtat ttttacagaa
    13801 atcacatttt aattatttta tataaaatca cccctctagt gttcataaac tagaggggga
    13861 atttgtatca tactatcgtt taacgcactt ctgcattgac tttttcttcg agcgatgctt
    13921 ggattttttc catatagcgt gcgacttctt cgtccgttaa gctatcttct ggattttgga
    13981 aggtcaagct ataagccatt gacttcatac caagtcccaa tttctcacct gagaagacgt
    14041 caaagagttt gatatctgtc aaacgtttca cgccggcagc ttggatagca tctacaactt
    14101 cttgatgagt cacttctgcc ttgaggagaa gggcaacgtc acggctgact gccgggaatt
    14161 tggtgatttc tacaaatgga gtcgctggct gaagcgcagc ttcgatagct gaaaggttaa
    14221 gctcagccac atacgtttct ggaatatcgt aagccttggc agtgactgga tgcacttggc
    14281 caaggaaacc aagaacttgg tcaccgagtg aaatcacggc tgtacgacct ggatgaaggc
    14341 tagcgatttc agatgttgct gtataggtta cttggagtcc caaacgagta aatagggctt
    14401 caaggattcc cttagcatag aagaaatcaa ctggaactgc tgctgtttgg aaatcttttt
    14461 cagcaaccaa gcctgtcaag gcaaaggcaa aactgttgat ttcatttgga agttcttctt
    14521 ttggattacc tgtttgttca aagacttttc caatctcgta aagggccaag tttttattct
    14581 tacgagccac gttgtaggca acggtatcaa ggatacctga aatcatattt tgacggagga
    14641 ctgaacgatc cacagtcatt ggccacatga gttccgtaag gttacttggt tgagccgtaa
    14701 actcaactgc tttttcagga gttgttagag tataggtgat gatttctgtc aaacctgctc
    14761 cttcagcaat agtacgaact tgacggcgga gtttttgtgt ggctgtcaat tcacctgctg
    14821 taccatcgtc ttttggtaga ctagttggca agcggtcata accatagata cgagcaattt
    14881 cttcaaagag gtcagcttcg attgtgatat cccaacgacg acgtgggact ctgactgtaa
    14941 agctgtctgc atttccagaa agaccaaagc caagacgacg gaagacgtct tctacatcag
    15001 cataagacag ctcagttccg aggacacggt taacatcagc aagggttgaa gaaacttcta
    15061 catctgaagt atcaagctca cccgctgaaa cgatgccctt acgcaccgtc gcacctgcaa
    15121 gttccgcaat caggctagct gccgcatcaa gggcttcatt aactgttgcc acattaattc
    15181 ctttttcaaa gcgagaagat gactcagaac gaaggttcag gcgaccactt gtcttacgga
    15241 tagatttgcc attgaaaaca gcagcttcaa ggacaacacg actagatttt tcagagattt
    15301 ctgttgcttg accacccatg acacctgcaa gggctactgg cttgtctgca acagtgatga
    15361 ctaggtcatt cacgtccaag tcacgttctt caccgtccaa ggtcaccaac ttttcaccag
    15421 cacgcgcttc acgcacacgg atgtcagtcc cttcaaatgt gtccaagtca aaagcatgca
    15481 taggttgacc aaagtagagc aggatgtagt ttgtcacgtc tacaacgtta ttgatgggac
    15541 ggatgccttc gttcatgaga aggttttgca accattgtgg acttggtgcg atagtcacat
    15601 tgtccaagat acgagctgca tagtaaggcg ccttgtctgt cccaatgctg acagaaaggg
    15661 catctgccgc agattcatta gtttctgtta gagtaaattc tttaaagttg actgccttgt
    15721 catagatggc tgccacttcg tgagccactc cacacataga aagggcatct gcacggtttg
    15781 gtgtgatgga aagttcgatg atttcatcat ccaagtctag gtaagaaaag acttcctcac
    15841 ctggcacggc attttctggc aagatttgga tgccatctgc gaattcctta ggcacaactg
    15901 agtcagaaat tcccaattca ccaagtgaac agatcattcc aagtgactcc aaaccacgga
    15961 tttttccttt tttgattttg tagttatcag cgatacgagc tcctggaaga gccaccatga
    16021 ccttgatccc agcacgcaca tttggggcac cacaaacgat ctgacgctct tcttcttcgc
    16081 caacgttaac ctgacaaaca tggaggtgag tctctggcac atcttcgcaa gacaagacct
    16141 caccgacgac aatttttgag agaccagcag ctggtgattc gacaccctct acctcgattc
    16201 ctgtagttga cattttttca gccaactctt gtgatggcac atcaatgtcc accaattctt
    16261 ttaaccattt ataagataca agcataattt agttctccag aatgacagtt gtcactctag
    16321 ttcttttcct ttcctatcat ttcaatagaa gaatcctctt cttaccttaa tttctttctc
    16381 agtaaccaat ccgtatctac tttttgacca accataaaat gatgttggct aaatttttca
    16441 aaaccatatc gattataaaa cgcttgagct tttgtattat gctcccaaac acctaaccaa
    16501 gcccaagaaa aactattttt tgtagcaagt tcaagtgcga attcaaacag ttgcttacct
    16561 agtccaaatc cttggaattt ttgtagcaca tagaggcgtt gaatttcaaa agcgtcctct
    16621 aattctctct cagtttgagc acttccccag ttgactttga gaaaaccagc tatctcctcc
    16681 tcatgcataa tgaaataggt ttcagagtca ggatttccca actcagttga caaagttttt
    16741 agactataag cctcttcaaa gtattcctgt aactgctctt ccgtattatc atacgcaaag
    16801 gtttcacgaa aggtttgttt ggcaatttta gccaacacct caacatctgc catttctact
    16861 tttctaatca ttatttaaac tgttctgaga agcggacatc tccttggtag aatccacgga
    16921 tatcgttgat tccataacgg agcatagcta cacgctcttg tccaagacca aaggcaaagc
    16981 cagagtatac agtcgcatcg ataccactca tttcaaggac acgtgggtga accataccgg
    17041 cccccataat ttcgatccaa cctgttttct tacatacatt acagccttct ccaccacact
    17101 tgaagcaaga aacatccacc tcaacagatg gctctgtgaa tgggaagtaa gatggacgca
    17161 aacgaatttg acgctcttca ccaaacattt tttggacaat caactgaagc gttccttgaa
    17221 gatcagccat agagatattt ttcccaacta ccaagccttc gatttggtgg aattggtgac
    17281 tgtgggtcgc atcgtccgta tcgcgacgga agacacgccc tggcgagatc atcttcaaag
    17341 gacctttaga aaaatcatgg gcatccatag cacgcgcctg aactggagac gtgtgggtac
    17401 ggagcaagat ttcttcagtg atatagaaag tatcctgcat atcacgagct gggtggtctt
    17461 ttggaaggtt catacgttca aagttatagt agtcttgctc cacttcaaaa ccatccacga
    17521 cttgataacc cataccgatg aagatatctt cgatttcttc actggtttgt gtcaaaacgt
    17581 gacggtgacc agtcgcaact ggacgacctg gaagcgtcac atcgatactc tcgctagcca
    17641 gttgagccgc gactttcttt tcttccaaga gcttagctgt ttcttcaaaa gcagcagtca
    17701 agacatcacg agcttcattg acgtgtttcc cgatgattgg acgcatctca gcagaaacat
    17761 ctttcatccc tttgaggatt tcagtgagcg aacccttttt accaaggaca gagacacgca
    17821 aatcttgcat ctctttttca tttccagcag taatctgctt caagctagtc agcgtttctt
    17881 cgcgaagcgc ttttaattgt tcttcaatag ttgacatatt tcctccatca gtctctcgta
    17941 gataaaaaga aaaccacatg ccaaaaactc cactcggagc gttgacacgc ggtaccatcc
    18001 gttttcatct gacaagtcag accttcattt ctaaatccat gcacaagtga attcacccag
    18061 ctttcatata gagagcttgc agtcacggct ctcctccctg atatacttcc cttgggctac
    18121 tagtctttca gattcctatt caattactac ttagtttatc agatttttac cattcttgca
    18181 agacctatct tacttctgct tgttagctta ttcttatcta aatttatata aacaatttat
    18241 ctaaattaac tatttataat ttttgtaaca aaattaaatt aattgacact cccctataaa
    18301 ataaagaagt ttagaattta atgtcttcca aacttcttta ttccatattt aatgaaatgc
    18361 caccttaacc gtgataatag ctagtcatca ataaaaaact atttgaataa ggattctcca
    18421 tttgattcaa tcacttcttt ataccaagta aaagacattt tcttatatcg atttaatgta
    18481 ccacttccat catcgtttcg atcaacataa atgagaccgt accttttaga aagttgtgca
    18541 gtggacatag aaacacagtc aatacatccc caagacgtat agcccataat ttcaacacca
    18601 tcctgtagag cttcagcaac ttgcaataaa tgttctttca tatactgaat tctataatca
    18661 tcttggacgg ttaagttatt aagttcatct tttattagtt gatctttagc acctaatcca
    18721 ttttctacta taaataatgg gatttgataa cggtcataat atctatttaa aattatacgt
    18781 agtccaattg gatcaatttg ccatccccac tctgaagact ctaaataagg atttactaaa
    18841 ccaccaataa tattcccttc tcctgaatta tactgtgttg gaagagcaga ttgagtcaca
    18901 ctcatgtaat agctaaagga taaaaaatct acggtataat tttttaataa ctctgcatct
    18961 tcagctgcaa actctatgtt aatgtcatgt tccttaaaat atctttttgc ataattcgga
    19021 taataacctc taacatgcac atctgaaaat agataattta gattctcata ctcatgagtc
    19081 gcccatacat cttttggatt tggagtcatt ggataagctg gcatagctaa taccatacat
    19141 cccaccttaa actctgaatt aatctcacga gcaatttttg taaccaaact tgaggcgact
    19201 aattcatgat gtatagcttg atataattct tgtttcgaaa gattctcctt aggtatatct
    19261 attcctccac tagtaaatgg taattccaaa acagagttta cttcgttaaa tgtaagccaa
    19321 tatttaactt tatctttata cctttctaaa actgttcgag caaatttttc ataaaaatga
    19381 atcattctcc tatcaaccca tccatgatat tttcttgcta aatataatgg agtctcatag
    19441 tgtgaaagag ttacaagtgg ttctatcccg tgagcatgta gttcatcaaa caattcatca
    19501 taatatttca acccagcttc gttaggttct tcctcatctc cttttggaaa aattctactc
    19561 catgcaatag aagtacgaaa aacattaaag cccatttcag aaaacaaggt tatatcttcc
    19621 ttatatttat gataaaaatc aatacctatc aattttaagt tatcttctgt aggattttct
    19681 gttgcttctc ctaatccacc tttgggtaac acatcctgaa ctgataagcc cttaccatct
    19741 tcattatatg ctccctctac ttgattagct gcaacagctc caccccaaag aaaatcatct
    19801 ggaaaaatgg tcataacttt cctccattat aagattacca gtaattcctt agaatgctcg
    19861 attgtctgat tattaggtaa tactaataca tctagaaaat cattggtatt cgttacaatt
    19921 accggtgtaa ctgtttcgta gcctttagtc ttgattaaat tcaagtccat ttcaaaaatc
    19981 aactgatttt tgaaaactct gtctccttct tctacatgac taataaaacc ttgacctttt
    20041 agctcaacag tatctaatcc aatatgaatt agtaactcaa caccctcatc actcttcaat
    20101 ccaattgcgt gcttagtcgg aaaaatattt gtaattttcc catcaaatgg tgcataaacc
    20161 ttaccttcac ttgggataat cgctactccg tctccaatta gtttatctga aaatgtttta
    20221 tcctggacat cgcttaacgg aatgatttct cctgatatag gagaaaatat cattttttta
    20281 tttgaaactc cagcttcaac ttctaaattg ctagaactct cttcttcatc gattccaaat
    20341 atataagcta atacaaaggt aataacaacc gaaatgaccg ccacaattaa agcatttaca
    20401 atatttgatg gcacatcaga ataaataaat tgaggcaacg ctatcaaaga tgggacagca
    20461 aatagatatg ctttaacact agtaagacct gcaaataatc ccgctaatcc accaccaatc
    20521 atagctgcat aaagcggttt tttatatttt aaagtcacac catataatgc aggttcggta
    20581 atccctgcaa gtaaggctga gaaacctgct gcaaaagcaa tttgttttgt attattattt
    20641 ttactcttta atgcaacagc catcgaagca gccccttgag ctaagtttga ccctaacatt
    20701 gctggaagaa ttaatacgtc tggagtagca atagatgccg ccaaaaaaat aggtgcaaaa
    20761 gcccaatgca ttccagtcat aacaataaat ggcataatag caccaagaat agctaatgta
    20821 agccatccag ctacaccata catttgccca actagatttg ataatccttc accaacaatt
    20881 actccaatag gtccgactac aactaaggca atacagcttg atactaataa tactagcgta
    20941 ggttgcaaaa aactcttagt aatagctggt gttaatttag caattatttt ttcaatatat
    21001 ttcatcaacc aaaccataat aagaattgga acgactgatg aaccataact agctggtgtc
    21061 acaggtgcac caaataaact aagaggattc cctgattgca ccatttgaac aaaatttgga
    21121 tggagaagta cacctgctac agacatagct aatgtagatg ttacttttaa tttttgtgat
    21181 gcagaataag ctaataacag cggtaagaaa taatatggag catccccaaa aaatgtcaaa
    21241 aaagcaatag tctgagaatc tgattgcaat ataccaagca ttggtaaaat gattaccaag
    21301 actttcaaca tacctccccc taacattgct ggaatgattg gagtcatgga accagcgata
    21361 tactcaatga ttctttctaa aatattccct ttgtgccctt gaacaactga atcggattca
    21421 aaattgccaa gtttaacgaa ttctttataa taattagcta catcattacc aagtataatt
    21481 tgatattgtc cattcttttt cataatacct attacacctg gtatcttctt cacatcatca
    21541 tcattgacta aattttcatc ttttaattct aatcttaaac gtgttacaca atgggtaact
    21601 ctattgacat ttttttcacc tccaattaca tcgaggattt tttgtaccgt atctttataa
    21661 ctcatggtat tctcctattc tattaatcta aattttttgt taagcgacga atatgagcca
    21721 tcaaataaac taattcacta gaagtcagca aataattgta ctccgtttgt ataaacattg
    21781 ccacctgttc accacattca tattctctag gatatttatt tttcattaat gctaacaagt
    21841 cttcatcatc atcgtcacaa taagttgtat tttcaaccaa gcgatgggca aataatttta
    21901 tatgagttat gaatctataa taatcaatag aatcttggtt aaactcagta caatagaaat
    21961 cttgaatgat tttctcaatt cccataatta tttcagtgat tttatacgac tcttgaaaat
    22021 tattttctaa attagcatta acaaaatgta gcgctatgaa tgcagcttcg tcaattggaa
    22081 gttcaatacc taactctttt tttattattt gtaaagccct tttcccaagt tcaaattctt
    22141 ctttataata tttcgagatt tcccagcgta ggggattcga aataataact ccttctttat
    22201 aacgttctat gctcgaagaa atatgatccg ttaaattaat atagataatt tcatcaaaat
    22261 tattacccaa tgttatttta cctaggttaa ttattttttc ggtgatgtac accaactcca
    22321 aaggaacgtt aataaacatc tctgtaaaac gggtcatatt atctctattt ttgagaaaaa
    22381 aacttttctc aatatcaatt ggatttactt tatctccagt ttttcttcca aaagctattc
    22441 cccttccaaa aagaagaata tcgatatctt ttttactttg cgcaattacg gcattgtggt
    22501 ttagtattcg ttttatgatc ataaaatttc ccttttaaaa taaaaggaac ctacttaaaa
    22561 acatcaagaa acttcttccg atgtgattaa ataggttcct gctcacttgt attagtgata
    22621 acatcctttt atttcaattt ttaatggtga catgaagctt aaatcattaa taactctgta
    22681 accattttca ttttaagata tttcaatcta tttgtcaagt acttatagaa atttttttat
    22741 tttgtgtgat tcgaatgtga taatgacaac agtctcacta aagaaatgaa aatcatacat
    22801 agaaattttt aaaaattttc tctatcgtaa acctgccact agttcagaag ctatactagc
    22861 tgattccaaa cgtaatatgg tcatctcatc taccttccct aataatggca ttgcaccata
    22921 ccaaacaata gtcttattca ccaaaagaat aggcgttact atttttgatt gagtaaaaga
    22981 cactttaatt ttctggctct tcaact
//
LOCUS       DAVDHC010000035        22902 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVDHC010000035 DAVDHC010000000
VERSION     DAVDHC010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.035"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(15..210)
                     /locus_tag="VUR43_001805"
                     /pseudo
     CDS             complement(15..210)
                     /locus_tag="VUR43_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(272..721)
                     /locus_tag="VUR43_001806"
     CDS             complement(272..721)
                     /locus_tag="VUR43_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET5413452.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(723..1481)
                     /locus_tag="VUR43_001807"
     CDS             complement(723..1481)
                     /locus_tag="VUR43_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET5413453.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(1596..3575)
                     /gene="pknB"
                     /locus_tag="VUR43_001808"
     CDS             complement(1596..3575)
                     /gene="pknB"
                     /locus_tag="VUR43_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET5413454.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLQSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3572..4312)
                     /locus_tag="VUR43_001809"
     CDS             complement(3572..4312)
                     /locus_tag="VUR43_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET5413455.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIITSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            complement(4327..5640)
                     /gene="rsmB"
                     /locus_tag="VUR43_001810"
     CDS             complement(4327..5640)
                     /gene="rsmB"
                     /locus_tag="VUR43_001810"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET5413456.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDISSIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5633..6568)
                     /locus_tag="VUR43_001811"
     CDS             complement(5633..6568)
                     /locus_tag="VUR43_001811"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET5413457.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6581..8977)
                     /locus_tag="VUR43_001812"
     CDS             complement(6581..8977)
                     /locus_tag="VUR43_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET5413458.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVFGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9043..9357)
                     /locus_tag="VUR43_001813"
     CDS             complement(9043..9357)
                     /locus_tag="VUR43_001813"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET5413459.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9382..10008)
                     /gene="gmk"
                     /locus_tag="VUR43_001814"
     CDS             complement(9382..10008)
                     /gene="gmk"
                     /locus_tag="VUR43_001814"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET5413460.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10138..11751)
                     /locus_tag="VUR43_001815"
     CDS             complement(10138..11751)
                     /locus_tag="VUR43_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET5413461.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(11942..12196)
                     /locus_tag="VUR43_001816"
     CDS             complement(11942..12196)
                     /locus_tag="VUR43_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HET5413462.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            complement(12200..12454)
                     /locus_tag="VUR43_001817"
     CDS             complement(12200..12454)
                     /locus_tag="VUR43_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET5413463.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            complement(12692..13789)
                     /locus_tag="VUR43_001818"
     CDS             complement(12692..13789)
                     /locus_tag="VUR43_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET5413464.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVNILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIADQNFGRVPIRIETN"
     gene            complement(13799..14545)
                     /locus_tag="VUR43_001819"
     CDS             complement(13799..14545)
                     /locus_tag="VUR43_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5413465.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNVLNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(14648..15001)
                     /gene="rsfS"
                     /locus_tag="VUR43_001820"
     CDS             complement(14648..15001)
                     /gene="rsfS"
                     /locus_tag="VUR43_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET5413466.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(15014..15514)
                     /locus_tag="VUR43_001821"
     CDS             complement(15014..15514)
                     /locus_tag="VUR43_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET5413467.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            complement(15515..16108)
                     /gene="yqeK"
                     /locus_tag="VUR43_001822"
     CDS             complement(15515..16108)
                     /gene="yqeK"
                     /locus_tag="VUR43_001822"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET5413468.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRSFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            complement(16108..16737)
                     /locus_tag="VUR43_001823"
     CDS             complement(16108..16737)
                     /locus_tag="VUR43_001823"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET5413469.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(16789..17100)
                     /gene="yhbY"
                     /locus_tag="VUR43_001824"
     CDS             complement(16789..17100)
                     /gene="yhbY"
                     /locus_tag="VUR43_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET5413470.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(17314..18420)
                     /gene="yqeH"
                     /locus_tag="VUR43_001825"
     CDS             complement(17314..18420)
                     /gene="yqeH"
                     /locus_tag="VUR43_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET5413471.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASDFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVVTRKAII"
     gene            complement(18423..19013)
                     /locus_tag="VUR43_001826"
     CDS             complement(18423..19013)
                     /locus_tag="VUR43_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET5413472.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(18965..19873)
                     /locus_tag="VUR43_001827"
     CDS             complement(18965..19873)
                     /locus_tag="VUR43_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET5413473.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(19930..20490)
                     /locus_tag="VUR43_001828"
     CDS             complement(19930..20490)
                     /locus_tag="VUR43_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET5413474.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            20629..21838
                     /gene="sstT"
                     /locus_tag="VUR43_001829"
                     /pseudo
     CDS             20629..21838
                     /gene="sstT"
                     /locus_tag="VUR43_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            21906..22859
                     /locus_tag="VUR43_001830"
     CDS             21906..22859
                     /locus_tag="VUR43_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET5413475.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
BASE COUNT         6143 a         5395 c         4509 g         6855 t
ORIGIN      
        1 attcgctaat tgtttttttt agggcgattg atttttactt ccgtcgcatc aatcattacc
       61 gtgtcttcag aactgagagg agttcttgaa atcgtaacac cacctttgaa caagagttac
      121 ttcaacccat tggctccgac ggagtaagtt gctttcgtgg ataccaaaat cagccgcaat
      181 ttcttcataa gtgcggtatt ctcgcacata tagaaagcgt tgttaattta tttatctcat
      241 ttttcagaaa attcttttat ttctgtaaag tctacgatac tcgatgtgtt tttatataat
      301 gatacagtct gagaatcact gttccgctag ccattccaat agagattacc aaagccaaca
      361 tgacaaccaa ggtcgcactt gccagtgctt tattatagtc ccctgtcaca aaaaaggcag
      421 ttgttcggta ggagagataa cctggaacca gcggtgccaa aatggccaag ataaagacca
      481 cagcaggtgt cttataaaga atacttaaaa tctggctgac acaagaacca ataatggctg
      541 caatgaaggt agctacaatg acattggtcg gttccttgag caagagatag attagccaga
      601 cagtcatgcc caaaatccct ccaggtaaga gcatagaccg ttgcacattg agtacgatta
      661 aaaaagtgat aatggcaaga aaacttgcta ctgcttgtaa taaaaaggtt gttagtgtca
      721 tattagttca tcaataccaa ggcgacagaa gttcctgccc ctaaagcgag ggtaatgagc
      781 agggattcaa acatcttact cataccagag tttatgtggt tggtcataat atcacggacc
      841 gcattggtca aggcaatacc tggtacaaac ggcatgaccg caccagctat aatcaaatct
      901 gccgttgaag gaaaacctgt gtagcgagcc caaaactggg caattatccc aaagacaaag
      961 gctccagcaa aggctgtcac aaagggaatt cggataaatt tttccacata gagggaaaag
     1021 gcaaaaccaa ataaggtcgc cactcctgcc ccaagtgcgt cgtagatatt tccgctaaac
     1081 ataactgaaa agaaaggagc actaaaggtc gcagccagag ttacctgcaa cttagtatag
     1141 ggaaggggtt gagcttgcaa ggccgtcaat tgcttaaagg ctgtttctaa gtcaatctgc
     1201 cccccaacta gctgacgaga aatctggttc acatcgcaga ctttttcgat gttataagaa
     1261 gaggaggtca cgcgcttcat gcgcgaaata ttggtatttt caatagagaa aaagatagcg
     1321 gcaggcatgg caaggacatt gcaatccaca atcccctgcg aatgcgcgat tcgaatcatg
     1381 gtatcttcta cacgatggat ttctgagcca cttttaagga gaatagtccc cgctagcata
     1441 atcacatcaa tgacggcatt taattctttt gattcttcca tgctttcctc cttttatcaa
     1501 ctccctctat tctatcacaa atctggactc aaaaaaaatc tttgccatga aatcatgaca
     1561 aagattgatt actcattttg attatccatc tgcttttaag gagtagctga agttgtttta
     1621 ggtttgtaga ttgaaatctt gactctagtc ttatttaggt ctaccttttc acctgctcta
     1681 ggactttgtt caacaaccat gccttctaca ctacctgcag gcgctgtcgt cacttctaca
     1741 acttctatat tagcttcctt aatcccaaca atttgaatca aattgttctt agtaaactcc
     1801 aagctggaac caatgtaact cggcatggca acacttgtaa cttttttagc tactgtcaag
     1861 acaatttgag taggtttact cacatcataa gtcgttccgg cacctggact ttgtttcata
     1921 atcgttcctg gttcgctttc gctggactct tcttcctcta tcttaatcaa attctcagga
     1981 accttcttct gcttgagttc tgagattact tctgtagagt tccgtccaat atagttccct
     2041 aattgaatcg tcgtagcttt tttagctact gtcaaaacaa tttgagttgc cttgctcaag
     2101 tcataggtcg taccttctgg tagactttgc ttcaggaccg ttccagcctc actctcattc
     2161 gactcttctt cctcaatttt aatcaaatta tctggaactt ttttctcttt taattccgcg
     2221 ataacatcag aagatttccg gccgacataa ttactaattt ggaaggattg tttgcctgat
     2281 gagacaacca aattgatttt cgttccttct tttcgaccag ttccagcgcc aggatctgta
     2341 cggataatcc gcccttcttc caccttttca ctagcctctg tcttctcctc accaatctca
     2401 aaattggctt ttttgagcgt tgccttggcc tctgcaactg tctgacctgc cacatctgga
     2461 atggcaatgg ttgcaggagt tctggatagt atccaaataa gagaagctgc caccaataca
     2521 aggctggcca acaaaatcag gtaacgcatc ttaaatctat gttttttcgg tgcttgtggt
     2581 tggtaagttt cctctgtcac agcctggctt gggtttttga ttgatttgtg ttctgtctgc
     2641 gcttgaacct taggaataga tgtcaaggta ctctgagaaa ccttcggcaa ggtcttggta
     2701 tctgccttgc tcgtttcatc aaagattaac ttactttcat ttctacgatt gtaggacaag
     2761 ctactagaca agtccacata catctctgaa accgagcggt agcgattggt caacttttta
     2821 gcagttgcct tgataataac attttctaaa gcctgaggta cagatggatt ttctgcaata
     2881 acggactgca ggggtttctg gaaatgctgg agggcaatgg tcaccgcgct atccccgtca
     2941 taagggatat ggcctgtcaa catctcatag aaaataatcc ccatggcata gatatcactc
     3001 tgcacagtcg ccttcgaacc acgcgcctgc tctggtgaca agtaatgaac tgagcccaac
     3061 atcgagttag tctgggtcag acttgtctct gcaaaggcta cagcaatccc aaagtctgtg
     3121 accttggccg tcccatctgg tgtcaaaagg atattttgag gtttcaagtc cctgtgaaca
     3181 attcctcgag tatgggccaa gcgcatagcc aagagaattt gtcccatgat acggactgct
     3241 tcttcattag aaagaggata atgttccttg atatagcgtt tgaggtctag tccagcaaca
     3301 tactccattg caagatactg ttgaccgtct tcctcaccaa tatctgttat ccgaacgata
     3361 tgaggatggt ctagatctgc catagctctc gcttcacgct gaaaacgagc tacagctatc
     3421 gggtccgtct ggtagttggt cctcagaacc ttcactgcca cttcttcccc atctaagatt
     3481 aagtctttgg ctaggtagac atccgccatg cctcctcgac caatctgttt gacaatccga
     3541 tagcgtccgg caaaaatctt gccgatttgg atcattcttc atcctcctcg ttcatagaaa
     3601 caagggcaac cgtaatgttg tctaaacctc ctgcattgtt agcaaaacga acaagtgtct
     3661 ccgttttatc tgctaaagga atatcactgg ttataatatc acgaatctca ctgcctgaaa
     3721 tcatgttggt caagccgtca ctattgagca agagatagtc acctgactca aggataactg
     3781 tcccaaaatc aggctgaatt tcatcttttt gcccaataga ctgggtgata atattttttt
     3841 gcggatgagc ttctgcctct tctggtgtca attgaccagc cttgagcaat tcattaacca
     3901 aagaatgatc actcgtcaac tgatggtatt cttctccacg aatcaagccg atacgcgaat
     3961 caccaatatg agcatagata gcctgattat caataatagc aaggacttcc aaagtagttc
     4021 ccatgcctct gtaagcttca tcctgaccaa gctggtgaat cttttgattt tcaatttcta
     4081 ggtaatgggc gaaccattca cgcacttcat tgactgtatc gatctgagta tcaacccaag
     4141 ctacacccag gtctgtgacc gccatttcac tagcgatatt ccctgcgcga tgacctccca
     4201 tcccatcagc taaaataatc atggtacgtc cagctctatt gacatagtgg ttgacatagt
     4261 cttggttatt tgttcgtttc tgaccaacat ctgttaataa tgaaatttcc atgtgtcagt
     4321 tccttcctaa tccgatatct tgcgaaattg actgatgaag aatccatcac ttccatacaa
     4381 ttcaggtgta atgaggatac agccgtcttt catgatatcc ttacattcat gttctagttt
     4441 tacctgctcg aactcgggat gactctctaa aaaggcctta acgacttgaa aattctcctc
     4501 tgagacgata gtgcaggtgc tataagttat tataccacct ttgcctagta tttgacaaac
     4561 actacctaat atttctaact gaatttcctg caaggacgcg aaatctgccg tttctttatt
     4621 gtatttgata tctggttttc ggcgcaaaag accgattcct gaacaaggag catccaccaa
     4681 aatcttatca aaggaatcct ggtcaaaaaa ctcatgcacc tttctggcat ccaatttttg
     4741 agtttgaacc cgatctgcaa ctcccagacg ttgggcattt tcttgaatta aatccaactt
     4801 gtggtcgtac aagtccagag cagtaacctg acctgtcgta agataagagg ctatatgggc
     4861 tgttttccca cctggagccg cacaggcatc aagcactcgc tcatcacctt gtaaatcaag
     4921 cgtcggagca accagctgac tggactcgtc ttggatggta atggctccat ccgcaaacaa
     4981 attatgccct gcaaaatgcc cctgctcctt aaccagacca gtggttgcta aaagggaatt
     5041 attcgcctcc aacaaggctt ggatttcctc ttttcgactt aggtctgtta cacgaatact
     5101 ggctttgttt cgcactaaca agctttcaaa gatggctttt gctctctcct ctccgtattc
     5161 ttccttgagt ttggcaacta gccaaactgg gagagaatag gcaatggagt cacgcttgtt
     5221 ttttcgcttg atgctagaaa tatctggcca gccttcacgc aagatacggc gaaggagggc
     5281 attgaccaat ttttcactgc cttttttacg aagtttggcc aattccactg cttcattgac
     5341 cacagcatga tctggaatct tgtccaaata gcggagttgg taggcactca tgagaagaag
     5401 gacatagagc cagctgtcta actggtctct gtcttcgata aagtgggata ggtaccattc
     5461 cagagtcagt ttacgggcta ccgttccata gaccagctcg gtcactaagc ccttgtctgc
     5521 tgccaaaagt tgacttccct ttagatgctt atttaaggcg atatttgagt atgcttggtt
     5581 cacaaaaaca tcctctagca ctgctagagc taaacttcta gccgtttcta ctttagtcac
     5641 caaatcgttc tcctacagtc aatgtacgtc caactccgtt gaggaaggaa gcaatgtcca
     5701 tcttaggctt accagctggc tgcacttgtt tgagggatag agccccttca gccgttgcga
     5761 caatcaattc tttcttgccg atagagagaa tctcacctgg atttccctga ccttctactg
     5821 gtagggcttc ataaatctta aagcggtcgc ccttaaggaa agtatgggca acaggccagg
     5881 ggttcattcc acgaatttgg ttaaagagtt gacgattggt tttgttccag tccagttttt
     5941 cttcctctgg ctttatattt ggagagaagg taacctgact cgtatcctgc ggttcaggtt
     6001 tgatatcacc agcaatatag gcaggcagag tgtccaaaag caaatcacga ccaactagcg
     6061 ccaatttttc aaacaaggtg ccaacattgt cctcatctgt gatcggaatg ctgcgacgag
     6121 aaatcatatc tcctgcatcc atttccttaa ccatttccat gatggtcaca ccagcttcct
     6181 catccccttg aatcaaggca taatggatag gcgcaccacc acggtgtcta ggaaggaggg
     6241 aggcatgaac gttgacagca aagtccatgc tatcaaggag tttgcttggg agaaactgcc
     6301 caaaagcagc agtcacaatt ccatctgctc ctagcttcat aagatcttcc atctctggac
     6361 ttccagataa tttttcaggt tggtagatag atagtcctgc ttccttggca gcctgcttga
     6421 ctggggtttc ttggataact tttttacgac caacagcacg gtctggctgg gtcacaacgg
     6481 ctagaatttc gtaacggtca tctgtcaaaa gtccttttaa gactgttgct gaaaagtcgg
     6541 gggtccccat aaagattagt tttgtcatat cttctccttc ttataaaaat tgttgcggct
     6601 catggtcaat gctgagacgg agctcactat tttcccgttc ttgagtcaag gctaaaacct
     6661 ggttgagggt cggccccagc tcatcttcta aacggtattt aattaaaatc tggtaatgat
     6721 agaggttgtg ggtacgggca atcggttttg gcgttggccc cagaatggga ctggtctctg
     6781 acaagcctga ccgcaaaatg ttcatgactt cataggcacg tttgaaaacc tcttcttctt
     6841 tcttgtgaga aagggtaata ccaatcgtga aatagtaagg tggatagccg agttgtcgtc
     6901 tgattcccat ttcataggca taaaagcctt cgtaatcttg atccttggca aatcgaatag
     6961 catagtgctg cgaattgtag gactgtatca agacttgacc tgctttttca gcccgacctg
     7021 ctcgacctgc cacctgagtc aagagctgga aggttctctc agaagaacgg aaatcaggca
     7081 gattcaaggc cgtatccgca tttagaactc cgactagggt aacattggga aaatccaaac
     7141 cctttgcaat catctgagta ccaagtaaaa tatccgcttc ccctcgccca aactggtcaa
     7201 gcaaggcttg gtgactgcct ttctttcgag tcgtatccac atccatcctc aaaatgcgag
     7261 cttggggaaa gagttctgct agctcatcat aagccttctg agttcccgtc ccatagtaac
     7321 gaatactgtg gctcttacag ttaggacaga cctgaggaat atccttcgag aaaccacaat
     7381 aatggcagtt catagtcttg gtatccatat gcaaggtcag agaaatatcg cagttgggac
     7441 aagtatccac cgtcccacac tcccgacaca tgacaaagct agaataacca cggcgattga
     7501 gcatgagaac cacctgctct tttttaacca gacggtcttg gatagcctct agcaaaggag
     7561 gcgtaaagtt tgacgtctca ttttgtccga tatagtctcg aaagtcaatc acttgaacct
     7621 cagggattgt agccaaagga ttggcacgtt gggttagacg taagtgttga tagacgcctt
     7681 tgccagcacg tgcccggctc tctaagctcg gcgttgcaga tccaagtacc agagttgctt
     7741 gattatactg agcccgtaaa atagctacct ctctggcatg gtaacgggga ttgctgtcct
     7801 gcttataagc cgcttcatgc tcttcatcaa taatcatgac acccagattt ttcagaggag
     7861 caaagatagc agatctggca ccaacaacaa cttgggcatc gccacgctcc accttgcgcc
     7921 attcatcata cttttcgcca ttggataatc ctgagtgaag aatggctacc ttgtccccaa
     7981 aacgtgctat aaaacgctcg gtcatctgag gagtcaagga aatctcaggt accagcaaaa
     8041 tagctgtctt gcccttatcc agggcacctt ggataatctg caagtaaacc tcggtcttcc
     8101 cacttcctgt aatcccttga agtagaaagg gaggttgaga actgccaata gaactcacaa
     8161 ccgcatcacg cgcctgtctt tgttctggat ttaactccaa aggtctactt gcttcaattc
     8221 cttcaaaata agcagccgag cgtcgaactt ccttttggac tatggtaaca gcaccttgat
     8281 ccacaaagaa gttgacttgc tctcgcgagt aggactctaa caagctagcc aaggaagcgc
     8341 tctctggatg agacagcaga taatctctca gttccaactt tttcttggca cgtgtagaaa
     8401 tctcaacacc ttctaattga gcatggtcaa cctcatacca agactgggtc ttgaccttct
     8461 tttgatcgac tgcctgatat tccagaccaa gcaggccttt tctagtcaaa cgcatcattt
     8521 cagcttgctt acctaaatcc agagaagaaa aggctagcga atcttctgaa ccaaacaggc
     8581 gtactcgttc ttcctgactc aagccttcca gaggatagag aatcttgtca tagctagaat
     8641 tcagaaatcc cggaagcatg gccttgagga tagagatttt gtaggagaag acagatttgc
     8701 gtaactcctc agccagccag agttgttctg gcgtgagaac aggagaaaaa tccagcacct
     8761 ctgcaatatc ttttaaatct tgctccatct cttctccatc tgattgggac tccaaaccaa
     8821 aaacaatccc ttgaatcagg cgattaccct taccaaaagg cacatgaacc cgcatcccaa
     8881 cttccagcat tccctcaaat tcctccggaa tcctgtaact atagggctgg tccgtctgca
     8941 tcaagggcac atctacgata atcttagcta gggccatctt ctcacctcct ccttgtcagt
     9001 acattcttgc aatagaaaaa ataagattga gtccccccaa ccttaaattt tttcaccatc
     9061 ttctttttct ttagcaattt gctctttgat tttcttttct tcttcttctt tgcggcgttt
     9121 ttcttcttcg atacggcgac gcactgcttc acgttttcct tctggatctg ggtgaattgt
     9181 aacgtttcct gattcgattt cttctaaagc gcgaagagtt gatttttcag acttgaaacc
     9241 ttgagttgct ggggcacctg cttccaattc gtgggcacgt tttgcttcca agattacgag
     9301 tgaatatttt gaaggaacct tgtcgagcaa ggtatcaata gagggtttta acatcatttg
     9361 cttgtaccta ttttctaaat tttatcgggt agttggagat tttggtaaca tctcctgata
     9421 gtgaccaatg acacgatcca cacagaagtg ttctgcttca atcacacatt tgacacgttc
     9481 agcagctagg ggcacctgat cgttgacaat cgcataatca tactcacgca tgagggcaat
     9541 ttcttccttg gccttttcaa ttcgttgggc aatcacttct gcactatctg ttccacgacc
     9601 taccaagcga tcttgcaatt catccaaatc tggtggtgtc aggaagataa agacagcatc
     9661 tggaaccttt ttcttgacct gaagagcacc ctgaacttca atttcaagga aaacatcgat
     9721 tcccttgtcc aaggtttcat tgacataggt cagaggagtt ccatagtagt tgccgacata
     9781 ttctgcgtat tccaacatct gtccttgacg aatcagctct tcaaattctt cacgagtacg
     9841 gaagaaatag tcaacaccgt ccacttctcc aggacgttgt gcgcgtgtcg tcatcgatac
     9901 agaatattga aattggtttt cagaactctc aaaaatctct cttctaaccg ttccttttcc
     9961 aacccctgaa ggaccagaaa aaacgattag taagcctcgg tctgccattg tgtctccttt
    10021 tagtcaatct gtgaaataac atttctctag aataatggca aaaagccaga ttatccttta
    10081 cagtctttct atctagtgta acaaaaaagc agtaattttt caactgctct ttcttattta
    10141 tttagcataa tctactgcac gaagctcgcg aatcacggtt accttgatat ttcctggata
    10201 atcgagattg ttttcaattt tcttacgaac tttgtgagcc aagattgtga ctttgtcgtc
    10261 cttgattttt cctggattga ccatgatacg aatttcacgt cctgcttgaa gggcaaagct
    10321 agtttgcact ccttcaaagc cgttagcaat ttcttccaaa tcatggagac gcttgatgta
    10381 gctttcaaga gactcactac gagcacctgg acgggctgcg ctcaaggcat ctgctgcagc
    10441 gacgataact gctatcacgc tctcagcttc aacatctccg tggtgactag caatcgtatt
    10501 caccacaact gggggttcct tgtacttacg ggccaattcc ataccgattt caacgtggct
    10561 accttcaacc tcatggtcaa tggctttccc gatatcgtga aggaatccag cacgacgggc
    10621 aagagccgca ttttcaccaa gttcgctcgc catgatacca gccaacttag caacctcaat
    10681 cgaatggcgc aaaacatttt gtccatatga agtacggaac tgcaaacgtc ccataatctt
    10741 catcaagtct ggatgaaggt ttggcgcacc aatttcatag gcagcagcct caccgtattc
    10801 acgaatctta ttgtcaatct cttgacggtt tttctcaacc aactcttcga tacgagctgg
    10861 atgtatacga ccatctttga gcaacatttc catagtcata cgggcaatct cacgacgaat
    10921 cggatcaaat cctgacaagg tcaccacttc tggtgtatcg tcgataatca catcgacccc
    10981 tgtcaaactt tcaaaggtac gaatgttacg accttcacga ccaataatgc gtcccttcat
    11041 agtatcgtct ggcagatgaa ccgttgagtt tgttgactcc gctacatatt caccagcgat
    11101 acgttgcata gcttgaacca agatgtcctt ggccattttg tcagaacgtt ccttgacctc
    11161 ttgctcagct tcgcgaatgc gactggcaat ctccctggtc aagttttcct ctgtctgagc
    11221 caagataata tctcgtgctt ctgcctgaga cagagcacca atacgctcta gttctgcttc
    11281 tttttgtctt tcgacttcct ctaattgctc ttcacgcgca tcaaggtttt tcgctctatc
    11341 agaaatactt tgttcttttt gttcaagtgt ttgttcttta ctcgtcaaat tgtcgtcctt
    11401 acggtcaagg ctagtagctc tctctgtcaa acgactttcg atttgtttga gttcttgacg
    11461 ttctgatttg aattcagcgt ccacttcttc acggtatttt ctggcttctt ctttggcctc
    11521 caatagtgct tcttttttaa gagacttgct ttcacgtttg gcttcattaa caagtaaatc
    11581 cgcttcacgc tcagcttgtc cacgtaaatt agttgcttct tgttcagcat ttaaaagcat
    11641 caactctgca gcttcctgag atgatttcat cttagctgag atgctgacat atccaatgac
    11701 taaaccaatg atgacggcaa aaacagcaat cgcaagcgac atgatttcca tgtttttacc
    11761 tcattttatt gttattccga atgacataca ttcttttaca ttctaccata aaaaagtgat
    11821 tttcacaaac ctaaaataga atatgttttg gggaatttgg aacacattta ccaaaataaa
    11881 cttgttgttt agaaatagta gtttagtaga gacttgagaa aaagcctact ttgcagtaga
    11941 cttagtaatg atctttaaag gacaagaaag ccacgctatc tccatccatc atataaatca
    12001 agcgattttc tgcatcaata cgccgtgacc aggctccttg gtaatcatat ttgagtggct
    12061 ctggttttcc tattcctgta aatggatcgc gttgaatatc cttgattaat ttattgattc
    12121 tttttagtgt ttttttatct tggttttgcc agtagcaata atctgcccag gcatcttctg
    12181 taaacttgag cagcatttct tactcctcaa taacatggac ctgagtactt ccagcacgaa
    12241 cttgagccat tcctcgcaaa accttatcag aaagttcctt attttgagca attctcaggg
    12301 tttcttggat actatcccac tcactctttg aaaggactac aatgtcctca tctggatttt
    12361 tattgaccac cgtcaaaggc tcaaattcat catttacctt cttcatgtag tcctttaaat
    12421 gatttcggaa tgttgagtaa aggactgctt ccataaccat acctcgtttt agctcttttc
    12481 cactattata cacgaaaaga aagaaattgt caggaacttg tacaagattt tcttttctat
    12541 ctatttatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg
    12601 agtacggcaa ggcgacgttg acgcgatttg aatttgattt tcgaagagta ttattcgtaa
    12661 aaaatctcaa aaagtccacc tttcggtaga cttagtttgt ttctattcta atcggcactc
    12721 ttccaaaatt ctggtctgct atacttggct ttcctagttg gtaaatctgg tcagcctttt
    12781 gagtcatagc atcccaaggt tctttgccaa ttcggctgac tagactgacc tgacctttca
    12841 aagacttgag atgttgccta cctttttcag taaatccaag gacatgaatg gcttctggca
    12901 agtcactttc tctagcctgc atcaaaatat aggtcaatag gcgtctgaca cgcgccttgg
    12961 tgtaacgttt ggtagtcact aactcgacca attcttccac agactgggct gttttaatag
    13021 cttctttaat gcgcacagcc atttcttgat tgacctgata gatggtggtt aggtcgggat
    13081 ttgacaagat ttgatagcgg agcaagggaa aatagtcttc ccagatcacc ttactggcct
    13141 gctcaaatag ggcaacagaa ggcataaagc gttctaagaa atcttggtcc ttctgatgtt
    13201 gacggagggc tgtcgccgag gcaaagtcca catctttatt cacagaatgg taacctgccc
    13261 cctgacgctg aatcggatgc agcttgatat ttcgtcctgc aaccgccttg gcataggcca
    13321 gagcaagaac atgattgggg gtattacctg aaaaatcaag accagcaaat tccttccaca
    13381 tagcttgggt tttctgggga taggaaaggg aatcaggcag attttccaca aatttctcca
    13441 tctcagcacc tttctctgtg tataagtcag cgattttctg ataatctcga acttcctctg
    13501 tcccaaaaac tagactatca atgcccaagc gatccaagat attcacagct ccttgaccaa
    13561 agaaatcagc tgcctgaaca ctgactaaaa agggcaattc cactaccaag tctgcgccat
    13621 tttccagcgc catctgggcc cttgtccact tatccacaat agcaggctct ccacgctgca
    13681 tgaaattccc tgacatggca acaattttca gtccctctgc ctgatccagc aggtatttat
    13741 ggccattatg aaaaggattg aactccgcga taatacctgt gatggtcatg ctaatctcct
    13801 acttctgcgc cacaaaaaac caacgggtgc tagtttctgt tggctcctta tcctcaaagt
    13861 ctgcatagag tttgaaggac ttgaatccag cctgttccag caagatctca taggtcaaga
    13921 tctcataggt cctctcctca tgtacttcat cgtggcgact aaaggaaccg tcagcctcct
    13981 tgataaagaa agtcagctca tggacgatgg agtgaggaac ttcgtcctca tatgtatccc
    14041 aaagcatggc aaaatcttcc gcattttcat ggtaggaata gccagggaat acttcatctg
    14101 tctggtaggt cgagtgcacg tcaaagatga aaactccctc ttcattcagc acattgtaca
    14161 cgtccttaaa gacgtcccct acttccacct catcctgcat atagcagata gagtccgaat
    14221 aacacgtgac aaaatcgtat ttccctgcct tggacaaatt cagcatatta ccttctataa
    14281 aagcaatctt ttgcttggct gaagttgctc tcttctccgc aatcttcaac atatccgcac
    14341 tcaagtcaag tccagtcaca tcaaaaccag cctgagagaa gcgcactgat tgaattcctg
    14401 tcccacaagc caattccaag agtttctttc tctccttggt cttaggcaaa tgacgcagag
    14461 aaaaattcgt ccatttgtcg tataaactat cgtccatgac cgcatcatag accgccgcaa
    14521 aggtttcata agtcgccata atcatgatac taagagctcc atggtaaaca ccactagccc
    14581 tttacctttc tatcaatttt tctaaaataa gcaaagaaac ccagttgact acaactgagt
    14641 tcatcttcta agcaagagct tctgaaatat ctactgaatt cgcctcatgc catagcttct
    14701 ctagattata atgggcacgc atttcttctg aaaagatatg cacgacaaca gcaccgaggt
    14761 ccagtaagac ccagcctcca gctgcatcgc cttcgacatg gctaccttta aagcctgctt
    14821 gagctacttt ttcacggata ttagctgcga tagcgtccaa ctgacggcta ttcattgagc
    14881 tagtgatgac aaagtagtcc gtcacactag tcaaatcttg tacatcaagt gcgaggatat
    14941 cctccgcacg tttctcatca gccgctttca cgactagttc tagtaattct ttttcgttca
    15001 tttaatcctc tttttagaaa atatgtttgt aatctaggac atctgcaaag cgctcctccc
    15061 aaatgtcctc gtaaaattca ttaatcgttt ctgctggaat gtcatcccca tcaaaggttg
    15121 tgacagcacc ttctggaaca ataagctgat agccatattc aaaggcaacc ttgacagagg
    15181 tatccacaca atattctgtc tgcataccac ataaaactaa tttttcaatc ccctgcttat
    15241 ccaagtattc ttttaagcca gtttctttga aaatactgtt atacttcttc tgaaagacct
    15301 tttcagcagg ttttcgattt aaaagcgcag ataactgcca atcttctgat gtttgagctt
    15361 cagagttctc aatatgttga acatagataa tttcaatatt cttgcttcta gcctgatttt
    15421 gtaaataaga aattttttcc aatagacttt ttgtctggaa cccagtttct actaaaacat
    15481 tctgaacatc aatgattata aaagccgtct tcatttagtt ctctttcaaa tagtgcacaa
    15541 aggcgttata ggtttcaagg gtttggggat agatggggaa tccctgatga gctagatact
    15601 ccacggtacg agctgtttcg taggccaccg ccttattgag cgatagactt gcaatctcac
    15661 gcgccacatc tactccagga aaggatcgat tgtgctcgat atagtctgcg acgtagatga
    15721 ccttatctag gtctgtcatt tgaccagctc cgactgtatg aatttcaatg gctcgcagaa
    15781 tttcagaatc atgcaaatcc aaatcttcct gaattttgta aattccgacc ataccatgcc
    15841 agacattatt gccccagttt ttgaggtcag ggtctagctg gtaacggtca atcaaggcta
    15901 gaaattcctg atttgacaac tttttagcat agtcatgaag aagacctgct agacttgctt
    15961 tctcaacatc tacaccaaag cgctgagcta attccatagc ggcacgctcc acacctagac
    16021 aatgggttag acgtttctca ggtagaagct ctgccatttt ttccaacaag gcctcacggg
    16081 agcagttgat atagtcttga taggacatca gtagagcccc tccttctcga tgtagtctag
    16141 cactggctga ggtaggagaa agttgggttt ccgaccttgg gcaaggaagt cccgcaccat
    16201 gctggacgag atatccatga gcggtacgtc cacccagata actggatagg aagtccctac
    16261 cttgtagcgt ggacgctgaa cccccacaaa ctgaaccatg tcaaccagtt catcaattcg
    16321 gtaccactta ggcagatagt caaccatgtc ggcaccgatg ataaagtaat aatccgtatc
    16381 tggattcttc tctgtcaaaa tcttcatggt gtcgtaggtg taggaaatac ccttgcgctc
    16441 caactcaatg gtttcaatga ctaggccgtc aattccctca attgccaact caagcatctt
    16501 gagacgatgg tgttcaggga tggtttcctt tttatcaacg tgaggaggtt ggtattcagg
    16561 catgagaaga acttgatcca gtcccaactg ttgccgtact tgatccgcaa caatgagatg
    16621 ggcattgtga acagggttaa aattcccccc taaaatccca acttgtttgc gttttttctc
    16681 cttgatttct ggctccaact ctaccttggt aaagggagtc aatagttcga ttgtcatagg
    16741 ctagtcccct ttatttctct ataaaaacag ttatttggag tttcggtctt agatttcttt
    16801 gactttctta gaaatcttgc gattttcttt cttgctagat tgtttaaaca aaatcaagat
    16861 gcgtcctatt ttttggactg tatccacacc gatttcttct tccaaaattt cagctacttc
    16921 gtggatgttt tcatctgtgt tttgtaagag agtaaccttg attaattcac gcgcatcaag
    16981 agcttgacgg acgctggttt tgatttggtc gttgagtcca tttttcccga tttggatgat
    17041 aggtttgagg gtgtgtgcct ggctgttgag gaaggcacgt tgttttgatg ttaatgacat
    17101 aattttcttc cttgtttttg gatagttatt ttaggtggtg agggacggtc ggaactaatt
    17161 ttccaaagat ttcatctttg aaaaatggat ttcctgacct cacaattgag ccttggtctc
    17221 aattgtgccc cttgccaatc tacagattgg caatcacacc acggcaataa ctatcgctat
    17281 atgagctcac tttgttcgct cagcgatttt gttttaaata attgcttttc gtgtgacgac
    17341 ggcgacgcct tctggtgccc agacggcgac ttttgctgtg cctgttacac gaatccagcc
    17401 taggcctgag atgactaggt ctgtcttatc tttaatggta aagacatgct ggactagcct
    17461 tgggaaatct tctttttcct tgctatttgg tggtgtcaga agagttccca ggtgcttatc
    17521 gtagaaatca ctagctcctt caagcttgct acgatggagt ttgagttcat tatcaaagaa
    17581 agcagtaaat ccttgctttt ctcctgctat aaagtcaaag cgtcccaaac cacctaaaaa
    17641 tagggtttgc tcaggattaa gctgataggt cttaggcttg atttcctttt taggactgac
    17701 atacttgagg tttttggccg tcaagtagtg agccatctgg tggcggtgga taattcccgg
    17761 cgtatcgtaa atataagatc cgtcgtcaag cggaatctct attttgtcca aggttgtccc
    17821 tgggaagcgt gaagtagtga tgacattctg atcacccgtg atttcttgga taatagcatt
    17881 gattagagtt gattttccaa cgttggtcac accgaccaca tagacatcgc ggcccttacg
    17941 gtagtgttca atcttgtcaa tgacttcctt aatggcgtgt ttattttgtg ctgaagttag
    18001 gaccacatcg actggacgaa gaccttcttc atgggcacgt ttcatgagcc actggctaat
    18061 cttaccagac ttaactgact tagggaggat atctttttta tttcctacca agaggacatc
    18121 attgcccgag acgaaacgtg gtaaacctgg gatgacagat ccattaaaat caaagatatc
    18181 aatgacattg accactaagg catcactgtc tcccacctcg tgcaagagct tgaggaaatc
    18241 atcgttcgtc aactggacat ctgtgatttc attgtagtgg cggagacgga aacagcgttg
    18301 gcaatagact tcgccagtct ccaaaccttt ttcaagtgcc gactgggggg taaaaccaag
    18361 accagcttta tctgtcgtct gaatggttgc tccacaacca atacagagaa tttcttccat
    18421 agttaaattc cttttttata tgtaatcggt ccgtactttt cagtgatttt tctcataaca
    18481 cgacgctcac gagttcggtt aatctgcgtt ttgattgagt catgttggac caagggtttg
    18541 actaaaattg accgaatccc tgcacggtgg gctgctcgta tatctgtcat gagctggtcg
    18601 ccaaccatga ccacttcctt tttgtcatag tggaattcct tcatagcacg gtcaatacca
    18661 aatgtgaagg gcttcaaggc ccagtaaacg taatcaatcc caaatttctc aactgctcgt
    18721 tgaacgcgtt ttttggtgtt atttgacact acgataatgc caatacctgc gtcccgaagg
    18781 tcatgtagcc attgcttcat ctctggcgtt ccatcagggt tgttccaagc aatgagggta
    18841 ttatccaaat cgaccaaaac agccttgatt ccctgcgcct gcaggcttgg gactgtcaga
    18901 tcatagactg cttccacagc aaaatctggt atataatttt caatcgccat tctggctcct
    18961 tttcttaact ttttttcgca attttcctta gtaacaagga taaaacaatc cacaaacctg
    19021 cactagccaa actgatatag agccaagcat ggggctcatc tgttaaaggt aagggaacat
    19081 tcattccgaa aaagcctgtc acgactgcca aaacagctag caagactgaa atgatagtca
    19141 aggttgtcaa attgtcattc agattattgt ttagaatatt gttgtaagag gctgaaagct
    19201 gctgtaaaat ctgagagatt aggtctgtca tggataccag ctgatgagcc tcaatcatgg
    19261 catcatcaaa ctgttctctc tcaatctcat caaaactacg atacaaggca tgaccttgaa
    19321 tatgctctaa caaaatccga ttttgtttgg cagctgccgt tagataaacc ataccagtct
    19381 ccaaatcaga cagggcaaag aggtttttct tggtagttcg ctggcgcaag aggtcattga
    19441 cctcatccct actcttgtcc atctgctcaa tgacaggata gtaggcattg ctgataattt
    19501 ccagactggc aaagagaaac ttataaatcg aaagcgtgtc atggctctcc agataacgag
    19561 tcatctgttc aatgacatag gcgttcttgg tattactaat ggtaatcagg cgacgatgct
    19621 cgacaataaa ggtcatggga aaagtctcat agtaggcctt gtcctttttt acgtctagga
    19681 cattatagat aaaggtaacc gtcccacttt cacggtggta atccatgtgg gcgcgctcgt
    19741 ttctatccag tgcgtattca atggtttcct tgtccaaacc gtaaatttca gaaaggtctt
    19801 ctagtttatt caacttccct aggtctaggt ctatccaggt acaaccattg cccaactgct
    19861 tttctaaaac catcttttct ccttattaaa ctccctctat tgtaccacaa attacttaaa
    19921 ataacaggtc tagtctgtgc gtgagaaatt gctaacaact gtgatatttc ggttagggac
    19981 aaagtgaagg gcttgctcct cgctacgaag ctgtgtcgta cgaattccca cactgacaac
    20041 cttacccgat acagtaatcg gtccatttgt cagaacgacc tcatctccca catccagttg
    20101 acgttcaaag aggatgaaaa agccattgat gacatcagac agaaagcctt gggctcccat
    20161 accaatcgct accccagcaa taccagctcc agccagcaaa ctagaaactg gcaaacctaa
    20221 aatcgacaaa atgcagtaga gtaaaaagaa atatagcgta taattaaaca cattttctag
    20281 taaacgtgag atggtttttt ggcgtccgac atcatgacga gacattttta gagaaggttt
    20341 gacaattctc tgcaccatgg tatgaagcat ttttttagca atataaaata caatcaaaag
    20401 cagtaaaaga gaaatgacct tggttagaat attctcgata atggttgtca catctagctt
    20461 ttcaatataa gcctgaataa atttttgcat ataaaactcc tttatttcat tataccatat
    20521 tttcatcagt ctcattctcc ataaatattc aaaaaataga cagaaaattc ttgattttgt
    20581 ctatcattta tactataatc ataatcacta cacaaaaagg agattattat gaaaagaatc
    20641 attcatgctt ggaataaggc aagccttgtc aagcgtatct tgattggtat gctttgtggg
    20701 gaatcctagg actgaccctt cctaatctct cagggattgg gctactcggg aatttattcg
    20761 ttggaggtct aaaagctgtt gctcctatcc tagtctttgc cctcgttgcc aatgcccttt
    20821 cccaacatca aaagggacaa gatagcaata tgaaaactgt tgttttcttg tatatcctat
    20881 gatagggact ttcgccgctg ctcttgtagc tgtactagca agtttcatcg tccctattga
    20941 aattacccta aatagtgcca atactgaaat tgcaccacca gatggggttg ggcagatcct
    21001 cagcaacctc ttgctcaaac tggttgacaa cccagtcaac gccctgttta ctgctaacta
    21061 tattggaatc ttatcttggg cagtcatttt tggaatcgct atgagagaag ccagtaaaaa
    21121 tagtaaagaa ttgctaaaaa ctatcgctga cgtgacttct aaaattgtcg aatggatcat
    21181 caatctggct ccatttggaa tccttggtct tgtttttaaa accatttctg acaagggagt
    21241 cggaagcctt gccaactacg gtattttatt ggttctatta gtaacgacta tgctttttgt
    21301 tgcccctgtg gtcaaccctt tgattgcctt cttctttatg agacgcaatc cttaccctct
    21361 agtttggaac tgcctccgtg tcagcggtgt gacagccttt ttcactcgta gttctgcgac
    21421 taacattcct gtcaacatga aactctgcca tgaccttgga ctcaacccag atacctattc
    21481 tgtttctatc ccactcggtt ctactatcaa tatggctgga gtagcgatta ccattaacct
    21541 tttgaccctt gttacagtta acactcttgg aattcctgtt gactttgcca cagcctttgt
    21601 cctcagtgtg gtagcagcta tctcatcctg tgatgcttca ggtattgccg gaggttccct
    21661 ccttcttatc ccagttgctt gtagcctttt cggtatttct aacgatattg ccatacaaat
    21721 tgttggggtt ggttttgtga ttggtgtcat ccaagactca tgtgaaacag cccttaactc
    21781 ttctacagat gtcctcttta ccgccgttgc cgaatacgca gcaacccgta aaaaataact
    21841 catcaaggca agcctgctca tgtcttgtct tttacgcttt tattctaact tattaggaaa
    21901 ttcttatgtc tattagccaa cgtacgacca agctcatctt agctacctgt cttgcctgcc
    21961 tgcttgctta ttttctcaat ctttcgtcag cagtttcggc tggaattatc gctctcttga
    22021 gcctatctga tacgcgtaga agtactttaa aactggctcg caatcgtctt ttttctatgc
    22081 ttctagctct ggctatcggt gttctagctt ttcacttgag cggatttcat atctggagtc
    22141 tcggcctcta tctggccttc tacgttcctt tagcctacaa gatgggctgg gaaattggca
    22201 tcacaccaag cactgttttg gttagccatc tcttggttca agagtcaacc tctccagacc
    22261 ttctagtcaa tgaattcctt ctctttgcta ttggtacagg atttgccttg cttgttaatc
    22321 tctatatgcc ttcacgagaa gaggaaatcc agcactacca cacgctggtg gaagaaaagt
    22381 taaaagatat cctccagcgc ttcaaatact atttatccag aggagacgga cgcaaccgag
    22441 cacagctggt agcagaatta gacacgcttt tgaaagaagc cctcagactg gtctatttgg
    22501 atcactctga ccacctcttt caccagacag actaccatat ccactacttt gagatgagac
    22561 agcgacaaag tcgtatcctg agaaacatgg cccaacagat taacacttgt caccttgccg
    22621 ccagtgaaag cctgatctta gcgcaactct tttcaaaaat tgcaggtcaa ctgagccaga
    22681 ccaatcctgc ttctgatttg ctagatgaaa ttgaacgtta tctggaagtc ttccggaacc
    22741 gcagtctgcc caagacaaga gaagaatttg aaacccgcgc cacccttctt caactcctac
    22801 gtgaagccaa aaccttcatc caagtaaaag ttgattttta ccaaaaatat agacagtaat
    22861 actcttcaaa ccacgtcagc gtcgccttgc tgtatatatg tt
//
LOCUS       DAVDHC010000036        21117 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVDHC010000036 DAVDHC010000000
VERSION     DAVDHC010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21117
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.036"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            106..570
                     /locus_tag="VUR43_001831"
     CDS             106..570
                     /locus_tag="VUR43_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET5413476.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTSLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            727..1152
                     /gene="lacA"
                     /locus_tag="VUR43_001832"
     CDS             727..1152
                     /gene="lacA"
                     /locus_tag="VUR43_001832"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET5413477.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFIVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1183..1698
                     /gene="lacB"
                     /locus_tag="VUR43_001833"
     CDS             1183..1698
                     /gene="lacB"
                     /locus_tag="VUR43_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET5413478.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1709..2638
                     /locus_tag="VUR43_001834"
     CDS             1709..2638
                     /locus_tag="VUR43_001834"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET5413479.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIKGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQEFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2640..3620
                     /gene="lacD"
                     /locus_tag="VUR43_001835"
     CDS             2640..3620
                     /gene="lacD"
                     /locus_tag="VUR43_001835"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET5413480.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQRTATSWKERV"
     gene            3923..4495
                     /locus_tag="VUR43_001836"
     CDS             3923..4495
                     /locus_tag="VUR43_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413481.1"
                     /translation="MVSIFSSALPMVSGSVFADSALTTVDKANDIVLNVDGNKFYNVS
                     VSEDIVNAGQILEDYFYVDKFGNINLKGTPEELAKNIGISVQEASLMYEAVKELPNVY
                     ERGPVGFRFNLGPQVRGMGGWAAGAFATGYAGWHLKQFAVNPVTSGFVAVISGAIGWA
                     VKTAVENYWTVAVATVEVPFVNLVYTIDLP"
     gene            4893..5729
                     /locus_tag="VUR43_001837"
     CDS             4893..5729
                     /locus_tag="VUR43_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET5413482.1"
                     /translation="MYRILNPMNHNVSFVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLKGYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            5765..6082
                     /locus_tag="VUR43_001838"
     CDS             5765..6082
                     /locus_tag="VUR43_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET5413483.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6082..7773
                     /locus_tag="VUR43_001839"
     CDS             6082..7773
                     /locus_tag="VUR43_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET5413484.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            7982..9388
                     /gene="lacG"
                     /locus_tag="VUR43_001840"
     CDS             7982..9388
                     /gene="lacG"
                     /locus_tag="VUR43_001840"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET5413485.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9431..9682
                     /locus_tag="VUR43_001841"
     CDS             9431..9682
                     /locus_tag="VUR43_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET5413486.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDADLEEFKNLFLNFINPEEWDTISFDSDFMPFQ"
     gene            complement(9967..10728)
                     /locus_tag="VUR43_001842"
     CDS             complement(9967..10728)
                     /locus_tag="VUR43_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET5413487.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10910..11872)
                     /gene="nrdF"
                     /locus_tag="VUR43_001843"
     CDS             complement(10910..11872)
                     /gene="nrdF"
                     /locus_tag="VUR43_001843"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET5413488.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(12060..14219)
                     /gene="nrdE"
                     /locus_tag="VUR43_001844"
     CDS             complement(12060..14219)
                     /gene="nrdE"
                     /locus_tag="VUR43_001844"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET5413489.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLNNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14300..14518)
                     /gene="nrdH"
                     /locus_tag="VUR43_001845"
     CDS             complement(14300..14518)
                     /gene="nrdH"
                     /locus_tag="VUR43_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET5413490.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            14869..15132
                     /locus_tag="VUR43_001846"
     CDS             14869..15132
                     /locus_tag="VUR43_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET5413491.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            15138..16871
                     /gene="ptsP"
                     /locus_tag="VUR43_001847"
     CDS             15138..16871
                     /gene="ptsP"
                     /locus_tag="VUR43_001847"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET5413492.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETIIVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            17127..19580
                     /gene="phtA"
                     /locus_tag="VUR43_001848"
     CDS             17127..19580
                     /gene="phtA"
                     /locus_tag="VUR43_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET5413493.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNEDVDSLLKQLYALPLSKRHVESDGLVFDPAQITSRTARGVAVPHGDHYH
                     FIPYSQMSELEERIARIIPLRYRSNHWVPDSRLEQPSLQPTPEPSPGPQPAPNLKIDS
                     NSSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKK
                     ENVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDD
                     LLAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAY
                     VTPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRV
                     KGEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDL
                     FATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEV
                     PQVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEK
                     LLALLKGSNPSSVSKEKIN"
     gene            19738..>21117
                     /locus_tag="VUR43_001849"
     CDS             19738..>21117
                     /locus_tag="VUR43_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET5413494.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSANDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSD"
BASE COUNT         6702 a         3792 c         4347 g         6276 t
ORIGIN      
        1 ttcggattac gaatgaattt gattgctggt attatcaatc atgaactagg attctagttt
       61 ttcaggaagt ctaataaaga aactagcaag gtcaggtctt actttattgg tggacatcca
      121 ggatttaatt gtcctctact tgatgatgaa gtctatgaag attattatct agagtttgag
      181 aaagaagaga tttgctctgt tccacgtcct ttcccagaaa caggtatgtt ggatttccaa
      241 gatagaagtc catggctaga gggacaaaaa gaaatagatc ttagttatga tcttttcagc
      301 acagatgcag tgactttgga tgaattgcaa tctcgaacaa ttgcccttcg ttctcttaaa
      361 catgataagg gattgaaagt gcattttgca gaatttccaa acctcatcat ctggtcaact
      421 ttgaacaagg gacctttcat tacctttgaa ccatggtctg gcttgtcaac atcccttgaa
      481 gaaggagatc atttagaaga taagaagaat gtttgtctct tagaagccaa tcaggttgaa
      541 gaattagggt ttgagataga agttttataa aaaagtaaaa aataaataac aaaaacaaac
      601 aaaagctgtt gacttcttca aacaatagta gtatattagg tttgtgagga ctaattgact
      661 gttttttaaa gacagtcaat acactgctgg aatccagcat agaaaaaata aaaaggagta
      721 tacaatatgt ctattgttat cggtgcagat gctgcaggtt tgagattgaa agaagttgtg
      781 aaagacttct tagaaaaaga aaacttccac cttgtggatg ttacagctga aggtcaagac
      841 tttgttgatg tgactctcgc tgttgctgca gaagtaaaca aagaagaaca aaaccttggt
      901 atcgtgattg atgcttatgg agctggtcca tttatagttg caactaagat caaaggaatg
      961 gttgctgcag aagtatctga cgaacgttca gcttatatga ctcgtggcca caacaactca
     1021 cgtatgatca ctatgggagc acaacttgtt ggtgatgaat tggctaaaaa tatcgctaaa
     1081 ggatttgtta atggtaaata cgacggtggt cgtcaccaaa tccgggttga catgttgaac
     1141 aaaatgggct aattagatta tagtaagaaa ggtaagttaa aaatgagaat tgcaattgga
     1201 tgtgaccaca tcgtaactga tgaaaaaatg gcggtttcag aatttttgaa atcaaaagga
     1261 tatgaagtca ttgactttgg tacctatgac catacacgga ctcactaccc aatctttggt
     1321 aaaaaagtag gggaagctgt aactagcggt caagctgatc ttggagtatg tatctgtggt
     1381 actggtgttg gtatcaacaa cgctgtaaat aaagttccag gtgttcgttc tgccttggtt
     1441 cgtgatatga caacagccct ttatgctaaa gaacaattga acgctaacgt tattggtttt
     1501 ggtggtaaaa ttactggtga attgcttatg tgtgatatca tcgaagcttt catccatgct
     1561 gaatacaaac caactgaaga aaacaaaaaa ttgattgcga aaattgaaca tgttgaaagt
     1621 cacaatgctc aacaaacaga cgcaaacttc tttacagaat tccttgagaa atgggatcgt
     1681 ggagaatacc acgactaaga ggtgacctat gattttaaca gtcacaatga acccatccat
     1741 cgatatttcc tatcccttgg atgagttgaa gattgatact gtcaatcgtg tggtggatgt
     1801 aaccaaaacg gctggtggta agggactcaa tgttacccga gtactttcag aatttggcga
     1861 ttctgttctt gctactggtt tagtgggtgg caaacttggt gagtttttgg ttgaacatat
     1921 cgataatcaa gtaaagaaag atttcttctc aattaaggga gaaactcgta actgtatcgc
     1981 tattctccac ggagacaacc aaacagaagt tcttgaaaaa ggtcctgaag tattggaaca
     2041 ggaaggtcaa gagtttttgg aacatttcaa aaaactcttg gagtcagttg aagtagtagc
     2101 catctcaggt agtctgccag ctggccttcc agttgattac tatgcgagct tggtagaact
     2161 tgctaatcaa gctggcaagc ctgtagtctt ggactgctca ggtgcagcac ttcaggctgt
     2221 tcttgaatca ccccataaac caacagtcat caaaccaaat aatgaagaat tgtctcagct
     2281 tcttggaaga gaagtttctg aggatttgga tgaattaaaa gaagtacttc aagaaccttt
     2341 gtttgcaggg attgaatgga ttatcgtttc acttggtgcc aacggtactt ttgccaaaca
     2401 tggtgacact ttctacaagg tagatattcc tagaattcag gtggtaaatc ctgttggatc
     2461 tggagactct actgtggcag gaatttcttc aggacttctt cacaaagaat cggatgcaga
     2521 attactcatc aaggcaaatg tccttggtat gctcaatgct caagaaaaaa tgactggtca
     2581 tgtcaacatg gccaactatc aagctctata tgatcaatta atagtaaaag aggtataaaa
     2641 tggctttaac agaacaaaaa cgtgtacgct tagaaaaact ttctgatgaa aatggtatca
     2701 tctcagctct tgcatttgac caacgtggtg ctttgaaacg cctcatggct caacaccaaa
     2761 cagaagaacc aactgtggcc caaatggaag aacttaaagt cttggtagca gatgaattga
     2821 ctaaatatgc ttcatctatg cttcttgacc ctgagtatgg acttccagca actaaagctc
     2881 ttgatgaaaa agctggtctt ctccttgctt atgaaaaaac aggttatgac acaacaagca
     2941 caaaacgctt gccagactgc ttggatgttt ggtctgcaaa acgtattaaa gaagaaggtg
     3001 cagatgcagt taaattcttg ctttactatg atgtagatag ctcagacgaa ctcaatcaag
     3061 aaaaacaagc ctacatcgaa cgcatcggtt ctgagtgtgt ggctgaagat atcccattct
     3121 tccttgaaat ccttgcttac gatgaaaaaa ttgcggatgc aggttctgta gaatacgcta
     3181 aagtaaaacc acacaaagtt atcggcgcta tgaaagtctt ttcagaccca cgctttaaca
     3241 ttgatgtttt gaaagttgaa gttcctgtta acattaaata tgttgaaggc ttcgctgaag
     3301 gtgaagtagt ttatacacgt gaagaagcag cagccttctt caaagcgcaa gatgaagcaa
     3361 cgaacttgcc atacatctac ttgagtgctg gtgtatcagc taaactcttc caagatactc
     3421 ttgtatttgc tcatgaatca ggtgcaaact ttaacggagt tctttgtggc cgtgctacat
     3481 gggcaggatc agttgaagct tacatcaaag atggtgaagc agcagctcgc gaatggcttc
     3541 gcacaactgg atttgaaaac attgacgaac tcaacaaagt tcttcaaaga acagcaactt
     3601 catggaaaga acgcgtgtaa gaaagtcctc ctagtttagg aacatgaatc taaaaaaatt
     3661 taaaaaaagt tgtatgtaaa ggtttacaaa ataacttact tgtgctatac ttaaatcaca
     3721 agttaatatg aattagaaag taactatatg aagtataata aaaataggat atagtttatt
     3781 ttacgagcta ggaaggaaaa atacggaaac aatattgcca gaataaacta tatttagatg
     3841 cacatttcat tcattgtttt ataaaaggag aagataaacg gctactaaaa agagttttaa
     3901 agcgttagtt gtaggactag gtattgtttc aatattctca tcagccttac ctatggttag
     3961 tggttctgta tttgcagata gtgccctaac tacagtagat aaagcaaatg atattgtttt
     4021 gaatgttgat gggaataaat tttataatgt ttcggtttca gaagatattg taaatgctgg
     4081 tcaaattttg gaagattatt tttatgtaga taaatttgga aatataaatt taaaaggcac
     4141 tcctgaagag ttagcaaaaa atattggtat ttctgtacaa gaagcaagtt tgatgtatga
     4201 agctgtaaaa gagttaccca acgtttacga aagaggtcct gtaggttttc gtttcaatct
     4261 tggtcctcaa gtgaggggga tgggtggctg ggctgctgga gctttcgcta ctggatatgc
     4321 tggatggcat ttgaaacaat ttgcggttaa tcctgttaca tctggatttg ttgctgtaat
     4381 aagtggtgcg attggctggg ctgtaaaaac tgctgtagaa aattattgga cagttgctgt
     4441 agctacagta gaagtgccgt ttgtgaacct tgtttacacc atagatttac cttagaggtt
     4501 atttctttat gaatcattct tttaaaaaaa taactgtatt ttgttttata gtttcttgtg
     4561 ttctttgttt attagactta atgaatttta aaaatgtagc tactttttta tttttctgtc
     4621 ttcctgtttt tgttttgatt tacaaaaata aataaaaaca gagcctctgt ttgatgaatt
     4681 ttagaacata gttaagtttt aaaaaaagtt gtatgtaaag gtttacaaaa caaccgactt
     4741 gtgctatact taaatcacaa gttaatacaa ggtgagtgtt actaagtaat attaggcatg
     4801 atcacaggtg aattagaaat cagctgattt tctagttcat ttgtggtcat tttttgtact
     4861 catatacctt taagatataa aaggaggttg acatgtatcg aattctaaat ccaatgaatc
     4921 acaatgtctc gtttgtcaga aatgataagg gagaagaggt gattataatt ggtaagggga
     4981 ttgcattcgg aaaaaggaag ggggatttga ttgctgaaaa tcaggttgag aaaatctttc
     5041 ggatgaagac cgaagagtcc agagaaaact ttatggctct tctcaaagat gttccgcttg
     5101 attttatcac agtgacctat gaaatcattg ataagctatc aaagaaatat cattatccga
     5161 ttcaagagta tctctatgta accttgacag atcatattta ctgttcttat caagctctaa
     5221 ctcaaggaag gtacaaggat agtaatctgc cggatatttc cgctaagtat cctgtcgctt
     5281 ttcaaatcgc aaatgaagct tttgaaattt accgtcagaa gctagcagat cattttcctg
     5341 aggacgagat tattcggatt gcttatcatt tcatcaatgc cgaaggtgaa aatgaagtgg
     5401 aacttgtgga gtcgattgat aagaggaaag aaattctcag gaatgttgaa gaagtgctaa
     5461 agggttatgc aattcaacga accaaaaaaa ataatcattt ctatgatcgc tttatgattc
     5521 atttgaatta tttcttggat tatttagaca gatctagaga tgataaccaa tcacttctgg
     5581 atatggaaga tcatattaaa caatcctatc caaaagcctt cgagattggt tccaagatct
     5641 atgatgtgat tacgcaacat acgggtcttg atttgtataa aagtgaacga gtttatctag
     5701 ttctacatat ccaacgttta ttgtcataaa aatttattta aaactatata aggagaattc
     5761 tatcatgaat agagaagaag taacattgtt aggttttgaa atcgtagcct atgctggcga
     5821 tgctcgttca aaactattgg aagccttgaa ggctgctgaa gctggtgatt ttgaaaaagc
     5881 ggacgctctg gtagaggaag ctggtagctg tattgcagag gctcaccacg cgcaaacaag
     5941 tctattgact aaggaagctt ctggtgagga cttagcgtat agtgtgacca tgatgcatgg
     6001 ccaagaccac ttgatgacaa ctatcttgtt aaaggatttg atgcaccatt tgatcgaact
     6061 ctataagaga ggagttaaat aatgaacaaa ctaattgcat ttatcgagaa aggaaagcct
     6121 ttctttgaga aactatctcg taatatctat cttcgtgcta ttcgtgatgg tttcattgca
     6181 ggtatgcctg ttattctctt ctcaagtatc tttatcttga ttgcctttgt accaaactca
     6241 tggggcttta aatggtctga tgaagttgta gcctttctga tgaaacctta tagctattct
     6301 atgggtattc tggctctctt ggtagctggt acaacagcta agtcattgac tgactcagta
     6361 aaccggagca tggaaaaaac caatcaaatc aactatatgt caacattgtt ggcagcaatt
     6421 gttggtttgt tgatgttggc agctgatcct atcgaaagtg gtctagctac tggattcttg
     6481 gggacaaaag gtttgctttc agccttcctt gctgccttcg ttactgtagc catctataag
     6541 gtttgtgtta agaacaacgt cactattcgt atgcctgacg aagttccacc aaatatctca
     6601 caagtcttta aagatgtgat tccattcact ctctcagttg tttcacttta tgctcttgat
     6661 ttactagctc gtcattttgt tggtgcaagc gtagctgaat caatcggtaa attctttgca
     6721 ccactcttct ctgcagctga tggctatctt ggtattacca ttatctttgg tgcctttgcc
     6781 ttcttctggt ttgtgggtat tcatggtcca tctattgttg aacctgctat cgcagcaatt
     6841 acctatgcaa atgctgaagt caacttgaac cttctccaac aaggtatgca cgctgacaag
     6901 attcttactt ctggtacaca aatgtttatc gttaccatgg gtggtactgg tgcgacactg
     6961 gttgttccat tcatgttcat gtggttaaca aaatcaaaac gtaaccgtgc aatcggacgt
     7021 gcttcagtag ttcctacctt cttcggtgta aatgagccaa tcttgtttgg tgcacctctt
     7081 gttttgaatc caatcttctt cattccattt atctttgctc caattgcaaa cgtatggatt
     7141 ttcaaattct ttattgaaac tcttggaatg aactcattca ctgctaatct accatggaca
     7201 actccagctc cactaggtct agttcttgga actaacttcc aagtgctatc attcattctt
     7261 gctgcccttc taatcgtggt tgacgttgtc atttactatc cattccttaa ggtctatgat
     7321 gaacaaattc ttgaagaaga acgttcaggt aagtctaatg atgaattgaa agaaaaagtt
     7381 gctgcaaact tcaacactgc aaaagcggat gctattcttg aaaaagcggg tgtcgatgca
     7441 gcacaaaata ccatcactga agaaacaaat gtcctcgttc tctgtgcagg tggaggaaca
     7501 agtggtctcc ttgcaaatgc tttgaataag gcagcagcag aatacaatgt ccctgtgaaa
     7561 gcagcagcag gcggctatgg tgctcaccgt gaaatgttac cagagtttga tcttgttatc
     7621 cttgcccctc aagttgcttc aaactttgaa gatatgaaag cagaaacaga taagctcggt
     7681 attaaactag cgaaaacaga aggcgctcaa tacatcaaat taactcgtga tggaaaaggt
     7741 gctcttgcat tcgtacaagc gcaattcgat taaggttaga gactctgaaa tagtctccta
     7801 tcgttacgga aatcgctatg gcgaatttcc tattattaat tcgtcggtaa aaagatatcg
     7861 tttttacctc ctcatgtcac aattcggtga cttggtacaa gaagtgagat ggagaaggat
     7921 ggctcactga ctcctctcct ctcactttta ctttatttaa atcaagaaat aggtgaaaaa
     7981 aatgacaaaa acacttccaa aagactttat ttttggtggc gcaacagctg cctatcaagc
     8041 agaaggtgct acacatactg atggtaaagg accagtagcg tgggataaat atcttgaaga
     8101 taactactgg tacactgcag aaccagccag tgatttttac aatcgatatc cagttgacct
     8161 caagctagca gaagagtatg gtgtcaatgg tattcgaatt tctattgctt ggtcacgtat
     8221 tttcccgact ggttacggcc aagtaaatgc taaaggtgtt gagttttatc ataatttatt
     8281 tgcagagtgt cacaaacgtc atgttgagcc ctttgtaact cttcatcact ttgacacgcc
     8341 agaagctctc cactcaaatg gagacttctt aaaccgtgaa aatatcgaac attttgtaga
     8401 ctacgctgcc ttctgttttg aagaatttcc agaagtaaac tattggacaa cctttaatga
     8461 aattgggcca attggtgatg gtcaatactt ggttgggaaa ttccctccag gtattcagta
     8521 cgaccttgcc aaagtcttcc aatcgcacca caatatgatg gtgtctcatg cgcgtgcagt
     8581 taagctatat aaagataaag gctataaagg cgaaattggt gttgttcacg ctctgccaac
     8641 taagtatcct ttagatccta aaaatccgtc agatgttcgt gcagctgagt tggaagatat
     8701 tattcacaat aaatttatct tggatgcaac ttatctaggt cgctattcag ctgaaacgat
     8761 ggaaggtgtc aaccatatct tatcagtcaa tggtggtagc ttggatcttc gtgaagaaga
     8821 ttttacagca ttagaagcag caaaagactt gaatgatttc cttggaatca actactatat
     8881 gagtgactgg atggaagcct ttgatggaga aactgaaatt atccataatg gtaagggtga
     8941 gaaaggaagt tctaaatacc aaatcaaagg tgttggtcgt cgtgtagctc ctgattatgt
     9001 accacgtacg gattgggatt ggattatcta ccctcaaggt ttatatgacc aaattatgcg
     9061 tgtgaagaaa gattatccta actacaagaa gatttacatc actgaaaatg gtctcggcta
     9121 taaagatgag ttcgtcgata acactgttta tgatgatgga cgtattgatt atgtgaaaca
     9181 acacttggag gtcttgtctg atgcgattgc agatggagcg aatgtaaaag gttacttcat
     9241 ttggtcatta atggatgtct tctcatggtc aaacggttat gagaaacgtt atggtctctt
     9301 ctacgtagat tttgaaactc aagaacgtta tcctaagaaa tcagctcact ggtacaagaa
     9361 agtagcggaa actcagatta tagactagta gaattagtca ttagatatag aattttagta
     9421 agtcaaaaag atgttcaaag attttatcca atctatttat gaaaaagttt atattataaa
     9481 tttcgaaaaa tgctctcaaa taccgtgttt gacgagtgaa gaattgaaaa gtcttggaaa
     9541 atggtatgtc tcgactggta aagaatggat ttgtcattca gatgctgatc tggaagaatt
     9601 taaaaatcta tttttaaatt ttatcaatcc tgaagaatgg gatactatct cctttgattc
     9661 agattttatg ccgtttcaat aatcgtaacc aatttctcaa aaaagttaaa tcttatattt
     9721 agtactctgt aaaactctta tctaatcacg ttgcttatac tcaatgaaaa tcaaagagca
     9781 actttaaact aggaagcgag tcgcagattt ctcaatgtat agctttgagg aattgggcaa
     9841 aaagtctttg atatagaaaa aagcatagta tcaggtgttt caacacctga tactatgctt
     9901 tttattgtgg gaagatttac tttttttctt ctgaaattga gttgttaccc aggctctttc
     9961 agtttattaa ggtttgatga ctttaatgtg tttagatagc ttaaaaagga ttgaatcact
    10021 tagtttagaa tctgaaacaa tagtatcaag atttgatata ttataaaaag tataaaaatc
    10081 aaacttattg aacttactat gatctgcgag taaatatttt ttattagaat tatttaaagc
    10141 gatgcgttga gcctctccct cttcctcgct aaaagtagct agagctccgt tttgaatacc
    10201 attacagcta acgaaagctt tagaaaattg gagattagag agattttgta gggtcaatgt
    10261 accaacaaaa gcacctgtaa tatcgcgata atttccacct attaaaatca aatctgttaa
    10321 ttttcgttcg cttaaaatca gaaaaacagg tagactgttg gttacgacgc ggatattgtc
    10381 aataggcaac tcacgcgcaa aaaactctaa tgttgttcct ggtccaatga aaatagtttc
    10441 tctttcttct actagactgc ctgcaaaatg ggctatttct tgtttttctg ccgtttggag
    10501 ggcttgtttt tcaatatttg atcgctcatt agtcaaaagg gagttggttc gaagtttttc
    10561 agctccacca tgcacacgaa tcagcaaatc tttatcagct aattcctgta aatagcgcct
    10621 tgcagtcata tctgaaacgg ctatttcgtc cataatctgt ttaactgtta tggttccttt
    10681 actatttact atctctaaaa ttttggttaa tttttcttgt ttgagcatat tatcacctcg
    10741 tttcctacta ctatcttacc ataaacaaac tcatcattca aatacaaaaa caacaaaatg
    10801 aaacaaaaac aaaaatatcg aagtttgttt tcaaaacttt cgatattttt gttgggttat
    10861 aactttgatg tttctagttt actttttgat gattgagagt gatggagaat tagtctaaac
    10921 cgtagttata gtcatcgtct tgcatggctt caacttcgcc aagaaggtaa ccatttccga
    10981 cttgagagaa gaagtcatgg ttggaagttc ctgttgaaat accgttcata acgattgggt
    11041 tgacatcttc agctgaatct gggaaaagtg gatcttgtcc catgttcatg agagctttat
    11101 tggcattgta gcgaaggaag gttttaacct cttcagtcca accaacaccg tcataaagac
    11161 tctctgtgta gccttcttca ttttcataaa gagtatagag taggtcgtac atccattctt
    11221 tgagtttttc ttgctcttct tcaggcaatt cattgaaacc aagttggaat ttgtaaccaa
    11281 tgtaggttcc gtgaacagac tcgtcacgaa taatcaattt aatgatttct gcaacgttgg
    11341 ctagtttgtt gttaccgaga tagtagaggg gagtgaagaa accagagtag aagaggaagg
    11401 tttcgaggaa gacgctggca actttctttt caagtgggct gccgtttagg tagatttcgt
    11461 tgacaatctc agccttcttt tgtaggtaag gattggtatt ggtccattcg aaaatttctt
    11521 caatctcagc cttagtattc aaggtagaaa agattgatga gtaagattta gcgtggacag
    11581 attccataaa ttggatgtta ttgaaaacag cttcctcatg tggtgtacgg atgtctgcgc
    11641 gaagggcttg aaccccagtt tcagattgca tagtgtcaag aagggttaaa ccaccaaaaa
    11701 cttttccgac caagtctttc tctttgttag atagctttct ccagtcatcc aagtcgtttg
    11761 ataagggaat acgtgtatcg agccaaaatt gctccgtcag tttttcccaa gttgatttgt
    11821 cgatgacatc ttcgatggca ttccagttaa tggctttgta gtaagtttcc atttaaaatc
    11881 tctttctgtg tttagtattg cgaactcaca attatttcta ctttaccata attctatagg
    11941 agtatcgcac aaaaagtcgg aagcccgact tttaaaatgt tacataaatt atgttatgac
    12001 atagtagatt tgattttatc agtgctgctt agggaaaaat aatgtttcta tgctagaaac
    12061 taaatcacac agctttcaca ttggttggcg ccgacttctc caccgtcatc tgtaaaggta
    12121 cggacgtagt agatagactt gattcccttg ttaaaggcat agttacgaag gatggacaaa
    12181 tcacgtgtcg tttgtttatt ttccctcttc cattcgtaaa ggccttttgg aatgtcactg
    12241 cgcatgaaga gggtgagtga aagtccttga tccacgtgtt cagtcgcagc agcgtaaaca
    12301 tcgatgactt tacgcatatc catatcgtag gcagaagtgt agtaaggaat ggtttctgta
    12361 gacaagccag cagcagggta gtagatttta ccaattttct tctcttggcg ttcttcgata
    12421 cgttgcgtaa tcgggtggat agaagcagaa acgtcgttga tatagctgat agaaccattt
    12481 ggcgctacag caaggcgatt ttggtggtaa agaccatctt cttgaacctt gtcgcgaagt
    12541 tcagcccaat cagcaacacc agggataaaa acatttttga agagttcttt aacacggtct
    12601 gatgttggaa caaattcacc agttacatac ttgtcaaagt aacttccgtt agcatagtct
    12661 gatttttcaa agttgtggaa ggtaatacca cgttcacgcg caatattgtt tgactctacc
    12721 aaggtccagt agttcataag cataaagtag atgcttgtaa attcaacaga ctcaggtgaa
    12781 ccatattcaa tgagttgttg ggcaaggtag ctgtgcagtc ccatggcacc gagaccaaag
    12841 gtgtgggctt ggctatttcc atggtcaatc gttggtacag ctacgatatg tgaactatct
    12901 gtaacgaaag taagggcacg aaccatagca cggatagaac gaccaaaatc aggtgaagtc
    12961 atcatgttaa ccacgttggt tgaacccaga ttacatgaaa catctgttcc catttgaagg
    13021 aattcttgag catcgttgat caagcttggt tcttgaactt gaagaatctc agaacacaag
    13081 ttactcatga taatctttcc atcaacagga tttgcacggt tagccgtatc gatgttgact
    13141 acataaggat agccagactc ttgttgcaat ttagagattt cagtttccaa atcccgcgcc
    13201 ttgatttttg tcttgcgaat atttggattt gcgaccaatt catcgtattt ttcagtaatg
    13261 tcgatgtaat tgaatggcac accgtattct ttttctacag agtaagggct gaagaggtac
    13321 atttcttcat ttttacgagc caattcgtag aatttatcag gtactacaac accaagtgat
    13381 agagtcttga cacgtacttt ttcatcagcg ttttctttct tagttgaaag gaaagcgatg
    13441 atatctgggt gaaagacgtt gaggtagaca acaccagcac cttgacgttg ccccaattgg
    13501 ttggagtaag agaagctgtc ttcaaaaagc ttcataacag gaacgacacc tgaagcagct
    13561 ccttcatagc ctttgatagg tgcaccagct tcacgaaggt tgttgagggt aattcccaca
    13621 ccaccaccaa tacgtgaaag ttgaagagct gagttgatag aacgtccgat agagttcata
    13681 tcatccgtca cttggattag gaaacaagat accaactccc cacgacgagc acgtccagca
    13741 ttcaagaagg aaggagtagc aggttggtag cgttggtgga tgatttcatt ggcaatatcg
    13801 attgcaacag cttcattccc atcagcgaaa taaagggcgt tgaagaagac acggtcttcc
    13861 atattttcaa gatagtattc accgtcatta gtctttaagg catattgatt gtaaaattta
    13921 taagctgcca tgaatgactt gaattggaag ttttggtctt tgataaattg agccaattct
    13981 tccaagaact ctggacggta tttcttgata aaggctgttt cgatgtagtt gtgttcaatg
    14041 aggtaattga ttttgtcttt gattgaatca aaaaccatag tgtttggaac tacattttct
    14101 ttaaagaaag catccaaggc ttccttatct ttatgaagca tgatttgtcc attaacagga
    14161 cggttaattt cgttattaag acggaagtaa gtcacgtctt caagatgttt taatcccata
    14221 aaatttccct tatctaatta caaaagaaag gcttctaagt tagccctaaa agcagtttct
    14281 tctggatgat gtactaagat tatgctaatt gtttcagttt tcctggttgg aaacctgaaa
    14341 agacttcagt tggtgtttgg ataacaggag ctgcgctaaa accgagctct ttaacttgat
    14401 cgacgtactc aggttgctca tcaagattga tttcacgata agagacatta ttactgtcca
    14461 agaaacgctt ggtcatttta cattggacac aattgttttt agaataaacg gttaccattg
    14521 tgtaactcct cttcaaaatt taatactatc ttagtatatc agaaaataaa attttgtcaa
    14581 tgatttgaac taaatatagt ggtgttcttt tgttgttttt atatataaac acaatatata
    14641 gtgtttgtat tgtgaaatag caatgattat cctataaatt gtttttaaag aaactatatc
    14701 ctgtgttttg ttatctagga tagaagattt tcagcaagtt atctgaaagg aaattgaagg
    14761 aaaatccaga aaatgcttga aaaaaatcct agaagatggt ataatactaa attgtaaggg
    14821 ttatcacata taactcaaaa aaagaaagaa caaaaggaga gtcaaactat ggcttctaaa
    14881 gatttccacg tagtggcaga aacaggtatt cacgcacgtc cagcaacatt gttggtacaa
    14941 actgctagca aatttgcttc agatatcact cttgagtaca aaggtaaatc agttaacctt
    15001 aaatcaatta tgggtgttat gagtcttggt gttggtcaag gtgctgacgt aactatctca
    15061 gctgaaggtg cagatgcaga tgacgctatc gctgcaatct cagaaacaat ggaaaaagaa
    15121 ggattggcat aagggaaatg acagaaatgc ttaaaggaat cgcagcatct gacggtgttg
    15181 cagttgcaaa agcatatcta ctcgttcagc cggatttgtc atttgagact attatagtcg
    15241 aagatacaaa cgcagaagaa gctcgccttg atgccgctct acaggcatca caagacgagc
    15301 tttctgttat tcgcgagaaa gcagtaggta cgctcggtga agaagcagct caagtttttg
    15361 atgctcactt aatggttctt gctgacccag aaatgatcag ccaaatcaag gaaactatcc
    15421 gtgcgaagaa agtgaatgca gaagcaggtc tgaaagaagt tacagatatg tttatcacta
    15481 tctttgaagg catggaagac aacccataca tgcaagaacg cgcagcggat atccgcgacg
    15541 tgacaaaacg tgtattggca aaccttcttg gtaaaaaatt gccaaaccca gcttctatca
    15601 atgaagaagt gattgtgatt gcacatgact tgacaccatc tgatacagct caattggaca
    15661 aaaactttgt aaaagctttt gtaaccaaca tcggtggacg tacaagccac tcagctatca
    15721 tggcacgtac acttgaaatt gctgctgtat taggtacaaa taacatcact gaaatcgtta
    15781 aagacggtga catccttgct gttaacggga tcactggaga agtgattatc aacccaacag
    15841 atgaacaagc ggcagaattt aaagcagctg gtgaagccta tgcgaaacaa aaagctgaat
    15901 gggcactttt gaaagatgct caaacagtga ctgctgacgg taaacacttc gagttggctg
    15961 ccaatattgg tactccaaaa gacgttgaag gtgttaacaa caacggtgca gaagctgttg
    16021 gactttaccg tacagagttc ttgtacatgg attctcaaga cttcccaact gaagatgagc
    16081 agtatgaagc atacaaggct gttcttgaag gaatgaacgg taaacctgtt gtcgttcgta
    16141 caatggatat cggtggagat aaggaacttc cttacttcga tatgcctcac gaaatgaacc
    16201 cattccttgg attccgtgct cttcgtatct ctatctctga gactggagat gctatgttcc
    16261 gcacacaaat ccgtgctctt cttcgtgcgt ctgttcacgg tcaattgcgt atcatgttcc
    16321 caatggttgc gctcttgaaa gaattccgtg cagcgaaagc agtctttgat gaagaaaaag
    16381 caaaccttct tgctgaaggt gttgcagttg cggataacat ccaagttggt atcatgatcg
    16441 agattcctgc agcggctatg cttgcagacc aatttgctaa agaagttgac ttcttctcaa
    16501 ttggtacaaa cgacttgatc caatatacaa tggcagcaga ccgtatgaac gaacaagttt
    16561 cataccttta ccaaccatac aacccatcaa tcctacgctt gattaacaat gtgatcaaag
    16621 cagctcacgc tgaaggtaaa tgggctggta tgtgtggtga gatggctggt gaccaacaag
    16681 ctgttccact tcttgtcgga atgggcttgg atgagttctc tatgtcagca acatctgtac
    16741 ttcgtacacg cagcttgatg aagaaactcg acacagctaa gatggaagag tacgcaaacc
    16801 gtgcccttac agaatgctca acaatggaag aagttcttga acttcaaaaa gaatacgtta
    16861 attttgatta atcgaaaagt ccctgcaact cagttacagg gacttttttt tgatatttta
    16921 aaaagaattt tcaagaaaat ctttcttata aaaagtccaa ccttgaaaaa gtagtggtca
    16981 gaacaaaaaa tacttatatg gttcataaaa ttcttgacaa gttggagatt taggagtaaa
    17041 ctattaacca gttaagtaat agagaggagt ttctgcaatt tagaaatgaa ttgcaactag
    17101 aaatatcaaa tagaaagaga gtttcgatga aaattaataa gaaatacctt gttggttctg
    17161 cggcagcttt gattttaagt gtttgttctt acgagttggg actgtatcaa gctagaacgg
    17221 ttaaggaaaa taatcgtgtt tcctatatag atggaaaaca agcgacgcaa aaaacggaga
    17281 atttgactcc tgatgaggtt agcaagcgtg aaggaatcaa tgctgagcaa atcgtcatca
    17341 agataacaga ccaaggctat gtcacttcac atggcgacca ctatcattat tacaatggta
    17401 aggttcctta tgatgcgatt ttcagtgaag aattactcat gaaagatcca aactataagc
    17461 taaaagatga ggatattgtt aatgaggtca agggtggata tgttatcaag gtagatggaa
    17521 aatactatgt ttaccttaag gatgctgccc acgcggataa cgtccgtaca aaagaggaaa
    17581 tcaatcgaca aaaacaagaa catagtcaac atcgtgaagg tgggactcca agaaacgatg
    17641 gtgctgttgc cttggcacgt tcgcaaggac gctatactac agatgatggt tatatcttta
    17701 atgcttctga tatcatagag gatactggtg atgcttatat cgttcctcat ggagatcatt
    17761 accattacat tcctaagaat gagttatcag ctagcgagtt ggctgctgca gaagccttcc
    17821 tatctggtcg gggaaatctg tcaaattcaa gaacctatcg ccgacaaaat agcgataaca
    17881 cttcaagaac aaactgggta ccttctgtaa gcaatccagg aactacaaat actaacacaa
    17941 gcaacaacag caacactaac agtcaagcaa gtcaaagtaa tgaggatgtt gatagccttc
    18001 tgaaacaact ttatgccttg ccactcagca aacgacacgt agaatctgat ggccttgtct
    18061 ttgatccagc acaaatcaca agtcgaacag ctagaggtgt tgcagtgcca cacggagatc
    18121 attaccactt catcccttac tctcaaatgt ctgaattgga agaacgaatc gctcgtatta
    18181 ttccccttcg ttatcgttca aaccattggg taccggattc aagactagaa caaccaagtc
    18241 tacaaccgac tccggaacct agtccaggcc cgcaacctgc accaaatctt aaaatagact
    18301 caaattcttc tttggttagt cagctggtac gaaaagttgg ggaaggatat gtattcgaag
    18361 aaaagggcat ctctcgttat gtctttgcga aagatttacc atctgaaact gttaaaaatc
    18421 ttgaaagcaa gttatcaaaa caagagagtg tttcacacac tttaactgct aaaaaagaaa
    18481 atgttgctcc tcgtgaccaa gaattttatg ataaagcata taatctgtta actgaggctc
    18541 ataaagcctt gtttgaaaat aagggtcgta attctgattt ccaagcctta gacaaattat
    18601 tagaacgctt gaatgatgaa tcgactaata aagaaaaatt ggtagatgat ttattggcat
    18661 tcctagcacc aattacccat ccagagcgac ttggcaagcc aaattctcaa attgagtata
    18721 ctgaagacga agttcgtatt gctcaattag ctgataagta tacaacgtca gatggttaca
    18781 tttttgatga acatgatata atcagtgatg aaggagatgc atatgtaacg cctcatatgg
    18841 gccatagtca ctggattgga aaagacagcc tttctgataa ggaaaaagtt gcagctcaag
    18901 cctatactaa agaaaaaggt atcctacctc catctccaga cgcagatgtt aaagcaaatc
    18961 caactggaga tagtgcagca gctatttaca atcgtgtgaa aggggaaaaa cgaattccac
    19021 tcgttcgact tccatatatg gttgagcata cagttgaggt taaaaacggt aatttgatta
    19081 ttcctcataa ggatcattac cataatatta aatttgcttg gtttgatgat cacacataca
    19141 aagctccaaa tggctatacc ttggaagatt tgtttgcgac gattaagtac tacgtagaac
    19201 accctgacga acgtccacat tctaatgatg gatggggcaa tgccagtgag catgtgttag
    19261 gcaagaaaga ccacagtgaa gatccaaata agaacttcaa agcggatgaa gagccagtag
    19321 aggaaacacc tgctgagcca gaagtccctc aagtagagac tgaaaaagta gaagcccaac
    19381 tcaaagaagc agaagttttg cttgcgaaag taacggattc tagtctgaaa gccaatgcaa
    19441 cagaaactct agctggttta cgaaataatt tgactcttca aattatggat aacaatagta
    19501 tcatggcaga agcagaaaaa ttacttgcgt tgttaaaagg aagtaatcct tcatctgtaa
    19561 gtaaggaaaa aataaactaa tgaaaaatga aagtctcgat aaagaggctt tcatttttat
    19621 tatgtatata tgtaaaattc ttgacaagca atattaaaaa gagtaaacta ttaactagtt
    19681 aattaaccgg tttattactt tatagtgaat caaatatact taagaaaaga ggaaagaatg
    19741 aaaatcaata aaaaatatct agctgggtca gtagctacac ttgttttaag tgtctgtgct
    19801 tatgaactag gtttgcatca agctcaaact gtaaaagaaa ataatcgtgt ttcctatata
    19861 gatggaaaac aagcgacgca aaaaacggag aatttgactc ctgatgaggt tagcaagcgt
    19921 gaaggaatca acgccgaaca aatcgtcatc aagattacgg atcaaggtta tgtgacctct
    19981 catggagacc attatcatta ctataatggc aaggtccctt atgatgccat catcagtgaa
    20041 gagctcctca tgaaagatcc gaattatcag ttgaaggatt cagacattgt caatgaaatc
    20101 aagggtggtt atgtcattaa ggtaaacggt aaatactatg tttaccttaa ggatgcagct
    20161 catgcggata atgtccgtac aaaagaagaa atcaatcggc aaaaacaaga acatagtcag
    20221 catcgtgaag gagggacttc agcaaacgat ggtgcggtag cctttgcacg ttcacaggga
    20281 cgctacacca cagatgatgg ttatatcttc aatgcatctg atatcatcga agatacgggc
    20341 gatgcctata tcgttcctca tggagatcat taccattaca ttcctaagaa tgagttatca
    20401 gctagcgagt tggctgctgc agaagccttc ctatctggtc gggaaaatct gtcaaattta
    20461 agaacctatc gccgacaaaa tagcgataac actccaagaa caaactgggt accttctgta
    20521 agcaatccag gaactacaaa tactaacaca agcaacaaca gcaacactaa cagtcaagca
    20581 agtcaaagta atgacattga tagtctcttg aaacagctct acaaactgcc tttgagtcaa
    20641 cgccatgtgg aatcggatgg ccttattttc gacccagcgc aaatcacaag tcgaaccgcc
    20701 agaggtgtag ctgtccctca tggtaaccat taccacttta tcccttatga acaaatgtct
    20761 gaattggaag aacgaattgc tcgtattatt ccccttcgtt atcgttcaaa ccattgggta
    20821 ccagattcaa gaccagaaca acccagtcca caaccgactc cggaacctag tccaagtccg
    20881 caacctgcac caaatcctca accagctcca agcaatccaa ttgatgagaa attggtcaaa
    20941 gaagctgttc gaaaagtagg cgatggttat gtttttgagg agaatggagt ttctcgttat
    21001 atcccagcca aggatctttc agcagaaaca gcagcaggca ttgatagcaa actggccaag
    21061 caggaaagtt tatctcataa gctaggagct aagaaaactg acctcccatc tagtgat
//
LOCUS       DAVDHC010000037        20011 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVDHC010000037 DAVDHC010000000
VERSION     DAVDHC010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.037"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(22..723)
                     /locus_tag="VUR43_001850"
     CDS             complement(22..723)
                     /locus_tag="VUR43_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET5413495.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQVSARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(802..2034)
                     /gene="murN"
                     /locus_tag="VUR43_001851"
     CDS             complement(802..2034)
                     /gene="murN"
                     /locus_tag="VUR43_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET5413496.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(2039..3259)
                     /gene="murM"
                     /locus_tag="VUR43_001852"
     CDS             complement(2039..3259)
                     /gene="murM"
                     /locus_tag="VUR43_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET5413497.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(3371..4150)
                     /locus_tag="VUR43_001853"
     CDS             complement(3371..4150)
                     /locus_tag="VUR43_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET5413498.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLG
                     TPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(4219..5880)
                     /locus_tag="VUR43_001854"
     CDS             complement(4219..5880)
                     /locus_tag="VUR43_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET5413499.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(6055..8277)
                     /gene="recJ"
                     /locus_tag="VUR43_001855"
     CDS             complement(6055..8277)
                     /gene="recJ"
                     /locus_tag="VUR43_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET5413500.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIGANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALIIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYRFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            8554..9312
                     /locus_tag="VUR43_001856"
     CDS             8554..9312
                     /locus_tag="VUR43_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5413501.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYTHKAVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDMTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            9323..10116
                     /locus_tag="VUR43_001857"
                     /pseudo
     CDS             9323..10116
                     /locus_tag="VUR43_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            10129..10806
                     /locus_tag="VUR43_001858"
     CDS             10129..10806
                     /locus_tag="VUR43_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5413502.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQV
                     NKKAYSL"
     gene            10816..11475
                     /locus_tag="VUR43_001859"
     CDS             10816..11475
                     /locus_tag="VUR43_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5413503.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISNLSHMLAKRWQQAA
                     E"
     gene            11619..12809
                     /locus_tag="VUR43_001860"
     CDS             11619..12809
                     /locus_tag="VUR43_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET5413504.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(13130..14011)
                     /locus_tag="VUR43_001861"
     CDS             complement(13130..14011)
                     /locus_tag="VUR43_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET5413505.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(14152..15480)
                     /gene="vncS"
                     /locus_tag="VUR43_001862"
     CDS             complement(14152..15480)
                     /gene="vncS"
                     /locus_tag="VUR43_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET5413506.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTKNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(15477..16133)
                     /gene="vncR"
                     /locus_tag="VUR43_001863"
     CDS             complement(15477..16133)
                     /gene="vncR"
                     /locus_tag="VUR43_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET5413507.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCIFTVRNVGYKLERK
                     "
     gene            complement(16182..16265)
                     /gene="pep27"
                     /locus_tag="VUR43_001864"
     CDS             complement(16182..16265)
                     /gene="pep27"
                     /locus_tag="VUR43_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET5413508.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(16445..17824)
                     /gene="vex3"
                     /locus_tag="VUR43_001865"
     CDS             complement(16445..17824)
                     /gene="vex3"
                     /locus_tag="VUR43_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET5413509.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHDWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(17876..18523)
                     /gene="vex2"
                     /locus_tag="VUR43_001866"
     CDS             complement(17876..18523)
                     /gene="vex2"
                     /locus_tag="VUR43_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET5413510.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(18536..19813)
                     /locus_tag="VUR43_001867"
     CDS             complement(18536..19813)
                     /locus_tag="VUR43_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET5413511.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         5730 a         4608 c         3593 g         6080 t
ORIGIN      
        1 aaagtaggga aagatagtac cctactcact agtctcatat atttttcgga ggtttgcaac
       61 atcctcttcc tggataccat aaaaggaacc tgctggttgc atgacagact tctcatctgt
      121 atggtccaag ccaatcgcat gacctaactc atgttctgcc gtatggacaa ggcgttcata
      181 ggagtagcca tagtatggat tggacaaata ataatgattc aaccgcaccg ttacggacaa
      241 gaattgccct gttaagagat tagtttgact ttccgcctct cctgccacag gagtgcctcc
      301 gtcgttcatc tccgtagccg taatatccgc cttactagac tcagtcacga gttcaaagtt
      361 aaaagcacca gtttgattcc agttctggat tgcttctaaa taagcctctt gaaagcgtga
      421 atccatctgc ggatccaggt aaatacgagc agagacctgt ggccaccttc cttcagaatg
      481 ctggtgacta tctgtctggc ttaacttagg cagttgccct gttttctccc attggtcaat
      541 actttgttga ccaattttta ctgaccgttc tgcttgcttt agcgctcctt gaaaatcccc
      601 gttcagatac cagagaagtc cgaaagcaag cacacataag agcacaacta tccaaaccag
      661 acgccaaaac aaacgccaca caaaagaaaa gaaagcccct atcaaacgaa aaagccagcg
      721 catgtctctc cacctttcta gcaaataaaa attattttac taaaagaagc taaaagaaat
      781 ctaaatactg actttttcat cttaacgtcc tactattttt ttgagtaact ggatagcttt
      841 gtattttaaa ggcgatggat ggtaacggaa agtacctgct ttgcgtacaa tatagccatt
      901 aaaattctgt ttaaaacgca aaacaccatc acttccatca aaaatccctt gaatgcctag
      961 gaagttgtat ttaggtattc cacgttttat gctttccaac ataacatatt tttgaagcag
     1021 tgcaggggca tagaacttat taaactcagt gtaggaacca ctaaagagat aagtcgtttc
     1081 ctgaggcata taaacaaata aactcccagc taaaacaata tcttcttctc catatttttc
     1141 aatcaagtct cgcgcttctg cttttcgaac ttcaaacgtt tcaaattgac tagaatattc
     1201 tctcagttga ttttgttttt tctcagaatg aggattttta ctcaaatcaa gtcgcaactt
     1261 gtccaagttt tcttctagtt tactttgttc accttgcaat ttgctcatat agtccgaaaa
     1321 attcaagctt gctatgagaa actccgcttg ttctccaaaa gtatcataaa aatgctcata
     1381 atattctaaa cttttatcac tatattctct acgttcagag gtttcttttg ttatattctt
     1441 aaaaatcgat agttcttcac gttttaactt tttcaaccga atgccaaagg tttcagcctt
     1501 tttcaccaag ggtttaccct ttttgctaaa acttttaagc aaactctttt cagttaattc
     1561 agttaaatct ttatagtata accaatctgg ttctccacct gggtaacctg ttgttaagcc
     1621 atcaaattga taacctaaat cagtcaaacc ttgaataata ctttttttct cagcatctat
     1681 tggattacct tggctatcaa aagtttgata agtttcataa ggttttacaa gcaactctaa
     1741 tacaccattt tgcttggcat attcttttaa ctctgcataa aaaactggaa gagcatcttg
     1801 ttgggtataa atcggccccg aattgagttc catatgcaga ccacccagca tgggcaagct
     1861 ataaaccaga gctgcaactt gaatttctcc ttcttgtttc aaagcaagat aaacaattcg
     1921 agcccctctt ttttctagca aatcccccat ctggacagat tgcataaagg aacgagaaga
     1981 aacctgatca gaataagtct gaaactcttc tttcgtgagt gttgttagtg ccatatactt
     2041 actttctatg tttttttctt aatgttttac ggaaatcaag agcaagtctt aacagaggat
     2101 agagaggatg agtgggcatt gtaaattcac ccaagtattc ttcaatcgtt ggattaaatt
     2161 tttccttaaa atgataaagt ccaccattga gagagttttc aacaccacct aaattttgcc
     2221 agaccatacc tcgctcaaag gcatagcgag ccgtttcata ccatgttaaa attggtgcat
     2281 tgtaacgttt aaaatcatca tccataccag catatatatt gacagaggta gtaccaaatt
     2341 ccaaactcaa agtagccgct aaaggaactc tcgcttgacc tacatctata tattcctgca
     2401 agaaggtcaa ttcctctaac aaacgttctt tttccttctt ctgcgcttct acttttgaaa
     2461 ttcgagtcga ctcagtaaag gtctcttcca aggctctatt tttcgctaac tgttcttcta
     2521 actcttgcga acgtttagaa acatccaagg tggccaaggt gatataggcc ttgtccttaa
     2581 aattatctaa caatttttta taataggctt cattcctcaa atgaatctct tttcgcttct
     2641 cagttttttt catcaactcc gaaaatgaat ctaatagttc cagtccacca tattgaatct
     2701 caagcccttt gtttcgtgct gttcgaatag cctgttttgt tgacttggaa agtttatctt
     2761 cttcaaaatt ttccttgtat attttcgcct gaatacgagg ttgaatggtg tctcccattt
     2821 cctccgtttt tcctgaccac cttactccca tttgttgcaa actatcaata atagccagat
     2881 tttcaggaaa ttctgtcttt tcctgattga ttaaactttg agataggcaa atacttgggt
     2941 caaaagtcac aaaaaccgct ctcttactgc gagcatagga cttaatagac tgaatggcaa
     3001 aattcaagag ttctttatcc ccataatcca atataggtcc tcttgggatg taaaacattt
     3061 tatagcctag cggaagagtt ctaatcaaaa tactagctgt cgccagtaat ttttcttccc
     3121 tgtaaacacc aaacttctca tgttgccaat tagacttaac ttcctcccaa gcactacttt
     3181 gtaatacatt ggctaattca tgttctttga caaactgatc atattctaat gtgggaatgc
     3241 caatttgata acggtacatt tcctactctc tttcctccag tattttatta ctattctact
     3301 actttcgttt gaaaagtcta gtgaaaacat attttatttt agttctactt cccctatgct
     3361 gaagttcaaa ctaagtcagt ctctcttcta atttgaaatc aattggtagg gttgttaaaa
     3421 aaacttccaa ttgtttttcc cagtagtacc actcgtgagt tccagcgcta tggctatagg
     3481 tcacatcaaa acctagtttt ttgagatttt tcactgcaag attattggct tcgtacaaga
     3541 aatcctgttc gccacaccac gcccaaagtt tggtcttttt atccgatttt ttagccagac
     3601 tttcaagaga atagggacta gttgtccagt ctttaatctc tccaaacaca cctctccagt
     3661 aggctggcgt tcccagattt tgactctcag gagaaaaatc ttgaaagctc aatgcacctg
     3721 aaaagctagc tgcatgagaa aaacgatttg tcgcaagagc cagtttgaaa cagccgtagc
     3781 ctcccataga aagaccagcg ataaaggtct tttcacgctt gctagtcata ttagggaaga
     3841 agcgtttcag aacctgtggc aattcctctg ctagagccgt gtagtagtca aaaccatact
     3901 gggtatcggt gtaccaacca ttgctggtat tgggcataac aacgatgaga ttagttcctc
     3961 gaagcaagcg ttctacattg gtccgcttaa gccaactatt atgattgcca gacatcccgt
     4021 gcaaaaggta caagacggga atatcttcac actctggttc ttccactcga ttggcatcag
     4081 ggtagaggac attcaccccc cactccatat ccaatacttg tgagtaatac tcgattttca
     4141 ttactgccat gattttctcc ttctattttt ctataagaaa aagccgaaac tcgactttct
     4201 ctctgtttat tttaacgatt attttgcttc catgactact ggtaaaatgg ctgggcgacg
     4261 cttggtttgg tcaaagagat acttggtcaa attatctcga accttccctt taagatctgc
     4321 ccagtcaaag tcatctcctt gaagatactc ttctaccgtt tggttaatca attctgaact
     4381 ttcacggaga atatcgcgac tcttcttgag ataaacaaat ccacgcgtgt gaacacgagc
     4441 cctagccaca attttcttct cacgacggtt gactgtaata gccacgatga aaattccatc
     4501 ctctgacaag accttacggt cacgaagaac aacatttcca acatcaccaa tggcattccc
     4561 atcaatcaag atatctcctg ctgaaaccga tccagctgga acaaagtctc cattctcgta
     4621 agccatggtc gtcccctttt taggaatgaa gatgcgttct ggcaacatcc caactgccat
     4681 ggcagcctta gcgtgagcat ccaactcacg atactcccct tggacaggga agaggtactt
     4741 aggttgcaaa agattgatca tcagctgcaa atcacgcaca tttccgtgcc ctgatacatg
     4801 taaactttgg gtaatcaatt tgacaacccc acctgcctga taaatcatat tttccacacg
     4861 cgcaacaaag gcttctttag caatagacgg agccgtagca atatagacca ggtccccatc
     4921 cttgatttct acataacgat ggcgaccaat cgacatctta cgaagtccat tgataggttc
     4981 acccatacga cctgtctcaa gaataatcaa ctcatggtct tcaaatcgag acatatcttt
     5041 aggcttaatc aagagaattt cgttggctaa agacaacttc ttaagacgaa tcgctgtgcg
     5101 gacgatattt tcaatatcaa atcctgtcaa gacgatacgt cgacctgttt tatccgcagc
     5161 gtcaaaaatc tgctgaatac gagaaagatt actggaaaca gctgcaacga tgatacgacc
     5221 ttcccagtca gcaatagttt gggtaatttc atccctaact tcactttcac tagccacctg
     5281 aatattgctg tctgcattgg ccgaatcact gaggagagcc aggacgccgt cacgaccaat
     5341 ctctgccaaa cgagcaaaat cagttgcata agattcacta gccgtttggt caaatttgaa
     5401 gtcacctgta taaacgatgc ttccttccga tgtcttcaag acaattccca gactctctgg
     5461 aacggagtaa gtcgtaggga agaaggaaac cactgtccca ccaaaatcaa tctccgtatt
     5521 ctcatcaatg acatggaaat cattaaattt cttaacggca tcatttcctt tgacaaagag
     5581 ctttgccaac tcaatggtca actcagaccc aaatacagga actttagcct ctgccaagag
     5641 atacggtaga gcaccaatgg catccgcatg cccgtgggtc aagaaaaccc cagcaatacg
     5701 gtcgctattt tcaaaaaggt aatccatgtt tggaatcacc acatcgaccc ctaattgttc
     5761 attttcagga tattttaacc ctacattcaa aacaaaaatg gactctccaa tttcagcaat
     5821 gtacatattt tttccattct cacgcacacc accaagtgtt gttaaactga tattactcat
     5881 ttttcctcca aaatcttagt ttatcttgat tatagggcaa ttctaccctc ttattctaaa
     5941 agttctgata ctttcagccg aatcttttcc taccattata ccattttttt gatgattttc
     6001 aaaatgaagg tctgttttca aaaaagagtt gatttcccaa ctctttccta acttctactc
     6061 tttttccatc aaaaaatcat aaatttcttg caccgtaccc agcgccatca tttcttggtc
     6121 tttaacggtt tgtttgagat tttggtaaat ttgactttct cctatctccc gctttggcgc
     6181 ctctttattg actgtcatca caccatcttt tatcgtcaca aagcctagtt cttcaaatac
     6241 ttgaatcatc ttgaccagca agatttgttg aatattaaga tatgcagcca aatctttcag
     6301 cttgtagcga atatcaaact ctgggaaccg gtaaatagtc ttgtacaatt tggcaaactg
     6361 atctctagtc ccataacctg tcagataata agccttgtca atatcatttt tgaaatagac
     6421 agcagagaaa tgctgttcct gaaaaatggt cttcagctga gtaatatcct ctggaatatt
     6481 ttttacgaca acagcttcac tagccgcaag atttggcagt tctccaggaa aatccaagac
     6541 tggaacacct tctggcaaga ctgcattttt tccacgaatg ttaaaaagtt gaacaccttc
     6601 cactcgcgca tccaccatca tcaactggag ggcagtttgg ccattccatt ggttgacaga
     6661 caatttaacc gctaactcta gattcttggt ttgagaaaac tctgtcgccc atctgccttg
     6721 accaaaggct accacttcaa aactcgcctc acccttggaa attttcagct ttagatgggc
     6781 attacctgcc cccatagtac gagcactttc gacctgaaaa ttcttgatat aaaaaatagg
     6841 tttctgatta tccattccaa aaggagctaa acgttcaaaa cttttgaccg tttccaagct
     6901 aagtgcctcc aaatccaact cttcatctag gtttaactta ttcttgccac cagcatctgc
     6961 acctttttca cgaacataat cttccaaaac ctgagataaa tctgagagtt gctcaacttc
     7021 caacgtcata cccgctgcac ctgcatgacc tccaaaggcg atgaagaggt ctcgatgggg
     7081 atccagagct tcaaaaatat cgaccgcttc cacactacga gcactgccct tggcacgacc
     7141 gtcttctata ttaagaacaa tgactgtctg tcccaattct tccaataaac gaccagccac
     7201 gattcctaga accccaggat tccagccttc cttggccaag acctgaacct tcttctcagg
     7261 atccaccatg gtcttggctt cttcatagat agactgaacg atttccttgc gctcttcgtt
     7321 tttctggtga attataaggg caatctcatg cgcttcctca tcatcaaatc cagtcaacaa
     7381 atcaatggca ggattgggat catccaagcg acccaaggca ttcaaacgag gagcaatctg
     7441 gaaaccaacc gtttcttctg ttacttcgtt ggcaccaatc ccagccatgt ccagcatttc
     7501 ttgcagacca atgcgctggg tatgacccaa catttccaga ccatattgaa ctaagatacg
     7561 attttcatcc gtcagactca ccatatctgc aatagttcca atagcgacca aatcaagcaa
     7621 ttccacttgc acttcttcta acagggcaca agccaacttg aaagcaactc cacaaccagc
     7681 caaatattta aaaggataat ccgcatctgg atgttcagga tggacaatag cataagcatc
     7741 tggcagggtt tcaggcatgg aatgatggtc tgtgacaatg acatctactc ccatagactg
     7801 agccaatgca atagcctcat gaccagcaac cccattgtcc accgtcacaa tcaaggaaat
     7861 cccttcttgc tcgataaagt atttataaac actagcatta gggccatagc catcggtaaa
     7921 acgatttggc aggtaaactc ggcactcagc accaagttgt tccaaacttt ccttcacaat
     7981 agaagccgaa gtcatgccat ccgcatcata gtctccataa acgagaatat tttccccttc
     8041 ttcaatagcc tgacgaatcc gctccactgc cttgtccata tcatggagca gataagcatc
     8101 atgtaagtcc tccaaggaag gttctaaaaa cttcttcaga ctttcttggt cctgaatccc
     8161 tctctcaaac aataaccgag ccacctcagg acccagtcca gccttcttgg ctatctttgt
     8221 aaaatccgca tcttctacct gcagggcaaa ctgccattca taagtaggtg ttatcaaaaa
     8281 gacatccact ctttctaaga attctattgc ttcattataa catgatttag acgttttctc
     8341 tatccagatt gcttttttat aacattttat agtatattga aactagaata gtacacctct
     8401 acttctaaaa tattgttaga aatcgatttg actgtcccga tcgatttgtc ctgttcttat
     8461 ttcactatag tgaatttttt cagatatggt ttgacaagaa cattctttta ttgtagaatc
     8521 gtgttataaa atctaacata aaggagatct ctcatggctt tagtagaatt taaaaacgtc
     8581 gaaaaatatt acggagacta ccacgcactc cgcaacatca atctccgttt tgaaaaagga
     8641 caagttgttg tcctgcttgg accttctggc tctgggaagt ccactcttat ccgtacgatc
     8701 aatggtttag aggctgttga caaaggaagt ctcctagtca atgggcacca agttgctggt
     8761 gccagccaga aagatttggt acctcttcgc aaggaagtcg gcatggtttt tcaacatttt
     8821 aacctttata cacacaaagc tgtgttagaa aacgtgacac ttgcgcccat taaagttcta
     8881 ggaattgata aaaaagaagc tgaaaaaacc gcccaaaaat atctggaatt tgtaaatatg
     8941 tgggacaaga aagattccta tcccgccatg ctatctggtg gacaaaaaca gcggatcgcc
     9001 atcgctcgtg gtcttgctat gcatccggaa ctcctcctct ttgatgaacc aacatctgct
     9061 cttgatcctg agactatcgg agatgttcta gcagttatgc agaaactggc gcatgatggg
     9121 atgaacatga tcatcgttac ccacgaaatg ggctttgctc gagaggttgc ggaccgcatt
     9181 atctttatgg ccgacggaga agttttagta gatatgacag atgtcgataa cttttttgac
     9241 aatccaagcg aacctcgtgc ccaacaattc ctcagcaaaa ttatcaacca cgaaagtgac
     9301 aaagtcaaat aaggaggcgc ctatgaaaaa aaaattcttt ttatcagcat tattgattag
     9361 ccttttcggc cttgctgctg ccaaaccagt ccaggctgat actagtatcg cagacattca
     9421 aaaaagaggc gaactggttg tcggtgtcaa acaagacgtt cccaattttg gttacaaaga
     9481 tcccaagacc ggtacttatt ctggtatcga aaccgacttg gccaagatgg tagctgatga
     9541 actcaaggtc aagattcgct atgtgccggt tacagcacaa acccgcgccc ccttctagac
     9601 aatgaacagg tcgatatgga tatcgcgacc tttaccatca cggacgaacg caaaaaactc
     9661 tacaacttta ccagtcccta ctacacagac gcttctggat ttttggtcaa taaatctgcc
     9721 aaaatcaaaa agattgagga cctaaacggc aaaaccatcg gagtcgccca aggttctatc
     9781 acccaacgcc taattactga actgggtaaa aagaaaggtc tgaagtttaa attcgtcgaa
     9841 cttggttcct acccagaatt gattacttcc ctgcacgctc atcgtatcga tgccttttcc
     9901 gttgaccgct ctattctatc tggctacact aataaacgga cagcactact agatgatagt
     9961 ttcaagccat ctgactacgg tattgttacc aagaaatcaa atacagagct caacgactat
    10021 cttgataact tggttactaa atggagcaag gatggtagtt tgcagaaact ttatgaccgt
    10081 tacaagctca aaccatctag tcataccgca gattaaggag gataccctat gacagattta
    10141 tcatcttgga cagcctattt tcaggatttt ggacaatttt tcaatggttt cctcttcacc
    10201 cttgccctag cgattggatc ctttatcctc gccatggtct taggaatctt ctttggtgcc
    10261 atgtcaacca gtaaacgtcc aattttacgc attttagctc gcatcttcgt ggaattttac
    10321 caaaacactc ccctcttggt gcagtttgtt attgtttttt atggcctacc tcttatcagt
    10381 gaccatatca tcatgattcc aatttattgg acagccgttc tctgcgtggg actctatcac
    10441 ggcgcttata tcgctgaggt tattcgttca gggattcagt ctattcctag tggtcagatg
    10501 gaggccgcct tgtcgcaagg ttttacctat atcagtgcca tgcgcttgat tatcttgcct
    10561 caggccttcc gcatcattct ccctccattg accaaccaaa ttgttaacct catcaagaac
    10621 acatctactg tagctatcat ctctggagta gacttgatgt ttgtgactaa gtcttggtcg
    10681 gctctcaacg gaaactatat cccagccttt ttaggtgctg ctcttctcta ctttgcccta
    10741 tgcttccctg ttgcccagtt tggtcgcaag atggagcaag tcaataaaaa agcctattca
    10801 ctttaggagg ttactatgga atctatttta gaaattttaa ccccagataa cctagtcttt
    10861 atctttaaag gatttggctt gaccctctat atttctctga ttgccatcat cctctctact
    10921 atcatcggta ccgtgcttgc cgtcatgcga aatggaaaaa atcctatctt acgcattatt
    10981 tccagtattt atatcgagtt tgtgcgcaac gttcccaacc ttctctggat ttttactatc
    11041 tttttggtgt tcaaaatgaa gtccacacca gcaggtatta cagcctttac tctctttaca
    11101 tcagcagcct tggctgagat tattcgaggc ggtctcaatg ccgtagacaa gggacaatac
    11161 gaagcaggaa tgtcacaagg cttcacctca gcccaaatcc tctactacat cattctccca
    11221 caagccatcc gcaaaatgct accagccatc atttctcagt ttgttaccgt gattaaggat
    11281 accagtctcc tctactctgt tatcgcccta caagaactct ttggagccag ccaaattctc
    11341 atgggccgtt atttcgaacc agagcaggtc ttcagtcttt acatcctgat tgccctcatc
    11401 tacttcagct ttaacctagc aatttctaac ctgtctcata tgctagcaaa acgttggcaa
    11461 caagctgcag aataacaaat tagctctcta gttcattgga gagttttttg atgatagtag
    11521 atatttatag acctcaattt gacaccatac attttctatg ataaaatgta acaaatttat
    11581 ttacaacaaa tcgaaatcta aatgaaatgg aattttctat gaaatcaatc aaaggactac
    11641 tctttatcat agctagtttt atcttgactc ttttgacttg gatgaacact tctccccaat
    11701 tcatgattcc aggactagct ttaacaagcc tatctctgac ttttatccta gccactcgtc
    11761 tcccactact agaaagctgg tttcacggtt tggagaaggt ctacaccgtc cacaaattca
    11821 cagcctttct ctcaatcatc ctactaatct ttcataactt tagtatgggc ggtttgtggg
    11881 gctctcgctt agctgctcag tttggcaatc ttgccatcta tatctttgcc agcatcatcc
    11941 ttgtcgccta tttaggcaaa tacatccaat acgaagcttg gcgatggatt caccgcctgg
    12001 tttacctagc ctatatttta ggactctttc acatctacat gataatgggc aatcgtctcc
    12061 ttacatttaa tcttctaagt tttcttgttg gtagctatgc ccttttaggc ttactagctg
    12121 gtttttatat catttttcta tatcaaaaga tttccttccc ctatctaggg aaaattaccc
    12181 atctcaaacg cttaaatcac gatactagag aaattcaaat ccatcttagc agacctttca
    12241 actatcaatc aggacaattt gcctttctaa agattttcca agaaggcttt gaaagtgctc
    12301 cgcatccctt ttctatctca ggaggtcatg gtcaaactct ttactttact gttaaaaatt
    12361 caggcgacca taccaagaat atctatgata atcttcaagc cggcagcaaa gtaaccctag
    12421 acagagctta cggacacatg atcatagaag aaggacgaga aaatcaggtt tggattgctg
    12481 gaggtattgg gattaccccc ttcatctctt acatccgtga acatcctatt ttagataaac
    12541 aggttcactt ctactatagc ttccgtggag atgaaaatgc agtctaccta gatttactcc
    12601 gtaactatgc tcagaaaaat cctaattttg aactccatct aatcgacagt acgaaagacg
    12661 gctatcttaa ttttgaacaa aaagaagtgc ccgaacatgc aaccgtctat atgtgtggtc
    12721 ctatttctat gatgaaggca cttgccaaac agattaagaa acaaaatcca aaaacagagc
    12781 ttatttacga aggattcaag ttcaaataag taatcatact ctcctgggat ttcccaggag
    12841 agttttttat agccaaatga aataagaccg gaacgatgga attttggcat tcaaatcaat
    12901 tgataagaat attttatagt ggagtgaaat aggatacgaa caaattgatt aggaaaatca
    12961 aatgaattta tagaaatctt ttagcagtta tgttgtccta ttctagtttc aaaacgctat
    13021 ggaagcagca ttgtgctagt ctagattcag tttactatac taaaacgagt agcttgaaat
    13081 caaaaaaccc accctcacag gcaggtttta tctgtattat tcagctagat tatgctttac
    13141 cttctgaacc gaatacgtcg atacgttctt caaccgatgc ttggatagct tttacaccgt
    13201 cagccaagaa tttacgtggg tcgaagagtt ttttcttgtc gtattctgct tcgtttgctt
    13261 cgtaatcacg agcaaattta cgagttgcgt tagcgaatgc gatttggcat tctgtgttaa
    13321 cgttaacttt ggcaacacca agtttgatag ctgcttggat ttgctcatca ggaatacctg
    13381 atccaccgtg caatacgatt gggaatcctg gaagagcttc tgtcaatttt tgcaagtggt
    13441 caaggtcaag accttcccag tttactgggt aagggccgtg gatgttaccg ataccagctg
    13501 ccaagaagtc gataccagtt tcaaccattg ctttagcgtc ttcgattgga gccaattcac
    13561 ctttaccgat gattccgtct tcttcaccac cgatagtacc aacttcagct tctactgaga
    13621 tacctttagc gtgtgctttt tcaacaactt ctttagccaa tttaaggttt tcttcaactg
    13681 gaaggtgtga accgtcaaac atgattgaag tataaccaac ttcgatacac tcaagtgcat
    13741 cttcgtagtg accgtggtca aggtggatag ctactggtac agtgataccc attgattcaa
    13801 caaggttagc gatcaagttg cgagcaactt tgtaaccacc catgtattta gcagcaccca
    13861 ttgaagtttg gatcaaaact ggagcttttt tagcttctgc tgcgcgcaag atagcttgag
    13921 tccactcaag gttgtttgtg ttaaatccac caactgcata accgttgtca cgggctgctt
    13981 ggacaaattt ttctgctgaa acgattgcca ttttatcagg cctcctgtat atttttatgg
    14041 gtcatcccat ttacattgtt cattttatca ctttttgcca aaaaaatcta gtttttcccg
    14101 cagtttcgat tgattttctt ctaactccat ctatgtaaac cctttctctc cctagtcttg
    14161 gacgactttt ggaaaatcta taaagaaggt taaacgattc tcctccatct cgaaacgata
    14221 agctaatttt tcatgttcta atagactctt aaccacaaaa agccccatac cagacccctt
    14281 gaccttgcga ctggcattgt cagaaaaaga ctgggctagt ttttcttgtt cctctgagct
    14341 acagctattt tcgataaaaa gttctccttc tctttctcca attcgaacta agccacctgg
    14401 aacagagtgc ttaatggcat tgctgatgag attagaaaga atcaacttca taactgatgg
    14461 gtttagataa gcctgctgat gggtcaaact attgtctatc tggagctctc tttccttggc
    14521 tagcaaggca taatctttga ccagattttt cgtcatctgg aggaggtcaa ttgtttccct
    14581 atcatctcgc aattcctgca cagaagagag ggaaagtatc tgcagaacat ggtgattgag
    14641 ttcatccaca atccccaagg caactcccag atactggtct ctatccttat aacgaccgat
    14701 attctctctc atattttcga ttaggatttt caaactagcc agcggtgttt tcaattcatg
    14761 agaagctcct cgtaggaatt cgaccttcat cttctccagc tggagaatgg cttcattctt
    14821 ttcatgcaag tccgcaataa cagtcaagag atgctggtag aggctattga tttgttcctt
    14881 gagattacct atctcatcct tagaatccac gcgcaatcgc acttgggaat ccaggtccat
    14941 catccgacgg gtcacccgct tgatttccaa aatcggtgca acaatagtcc gagcgtagat
    15001 gtaggccacc aagagggaaa tcagaaagga ggccagcaag gtatagggaa gaaactggag
    15061 actgatttgc tccgcttcct tttgtaaatc catggaagct agaaactgga gaatcatagt
    15121 accaccgtct tgcgttttca cctcgcgctc ctcaataaag agagaggttg tctggcggtc
    15181 tgtgtccaga ggaagactgt ccttgacttc taacttgtcc tcggtcatct cacctttgac
    15241 ggtccccttg atatcactag tctgggaata caagtctaac acttgctcga tactctgcct
    15301 atctttccct tctagggact gggcaatggc tgttgccttt tgaccaatgg tttcctgacg
    15361 atgactcaga taagtcgaag gaaaaagaaa ataaatagct aaatgaaggc agataaccag
    15421 aacactaaat atcgagaagg tatagataaa tatctttgta aataaacctg ttcgtttcat
    15481 tttcgctcca atttataacc aacattgcgc acagtgaaga tacaatccaa gtctagcttt
    15541 ttccgcaatt ccttgatata aacatcaata acacggtcaa agggaacctc atctgtcgct
    15601 ttccagacgg catcgataat ctgagaccga gtcaaggccc ggccttcatt tttcactaga
    15661 tagtccagaa tttccaactc tttggcattg ataggcactt cttgacctgc gaggcttgca
    15721 ctgtagcttt caaagtccac cttggtatcc ttgtaagaaa agattcgtcc tgtatcgtag
    15781 tagcgcttga aaatcgcgtc caccctcact tttaagaggg agagggagaa aggtttttcc
    15841 agatagccat ctgccaaaga ggcaaaggca ctcatcttgt attcctcatc ctgaaaagct
    15901 gtcaacatca agacaggaac ctgactggtt ttacgaatct cagctaggac ttctaagccg
    15961 ttaagcttgg gcatctggat atccagtaaa accagggcca cctcatagct agaaaattgc
    16021 tccagagctt cctgaccgtc cgctgcctca atagtttcat agccacaatc cgtcaaataa
    16081 tcactgaccc cctcacggat catctcttca tcttctacaa ttaaaatttt catactttaa
    16141 ctgctctcta ttttttattt ttcttagaat aaatacctac tctattttct attatagtct
    16201 cttgctggcc ttttgtctgt aagcaactga ccactagata aaacgttgtg aaattccttt
    16261 ctcataaatt ccataacttt agtatattat atttaagcac taaagtacaa agaaagcaac
    16321 tgaaagcaat gattttcacc actgctttca gatttatttt gaattgttaa atagctattc
    16381 ctatccacta ttcttgaata gaaacacaag atgcaatctt tattccagac tcattttttc
    16441 aaatttattc accatccagc aagagctctt ttggttgttt tctaaggaga ttgcttgaag
    16501 caagcgccat aacgagaacc actagaacca aggcaaggac aaaaatgatg ataaagtctg
    16561 atgtctgaat ggaaatgtct aggctcgaca aggtcttgct aaagccatct acttctgcac
    16621 cgccaccaag gttagaggct tgagccgcct tactagcctg tttggcaaca cctgaagtca
    16681 cattggcaag gacagtgttt ccaattgcac gggcagtgta attagctagg aagtaagcag
    16741 aaactagagc agggatagca atcaagatag attcggtgat gaattgaccc aagatacttg
    16801 cctgcttgag gccgatagag aggagaattc ccacttcctt gcgacgggcg ttgatccaaa
    16861 ggctgagcaa gagggcaagg aggagaactg agaagctcaa gctaccccag aagaggaggt
    16921 tggccatctt gtacatacca gagatagatt gctcaagagc tgggtagtta gaggagctct
    16981 tgacgagtgt gtagctcttc cagttgatac cactgatgcc attcaactct ttcataacat
    17041 catccaagtt cttgtctgct gttacaaaga aggttgcgtc cccataaatg gctgtgtctt
    17101 ctgtgtatcc ataaagtttt gcagcagtgt gaatgtctgt aatagctgtg ttttcgtaaa
    17161 gttcttgtga gtaggttact gctgacttat tatgaccatc aaagagtccc ttgattgtca
    17221 cttcaactgt ttccttggct cctttttcat tatctgcatc gtagatatta gagtccagtt
    17281 taaccttgtc ccctactttc cagtcgtgtt tggctgccaa gtccttgtgc aagaggattt
    17341 tatccttgtc gtcgttggtt aagtgctctc cttcgactag tttataagaa ccagagacaa
    17401 acttgtcttc tttagaggag tcattgacac ctgtaatcat caagctactt ccaaaacgtt
    17461 tggcacgatc agcagtgaga ttcttcttgg tttctggcgt ttcaatcagg tcatatccag
    17521 tcaaatctcc gatagcgttg atacgtttga cataagactc aatggccttg ttttcggtga
    17581 tttttttgat atcttcaccc ttgatattcc cagcaccacg aggcgttcct tggttgacgc
    17641 gacgattgat ttgcatggag aagctattgg tgatattttt aaaggtctcc tgagaagcct
    17701 tggcagtagc tcccttgatt gacaagccga ccaaactcaa gctcgccatg aggagaataa
    17761 tcaggaagat gacaatcgat ttgaaaaact tccttgtaac ataggcaaat gcgttgtgta
    17821 acatagattc cctttctaga ttttgtttta atcattctat caaaataagc tcaaattatt
    17881 tactagtatt gcgcgtttca gtcagtttct tatcctttaa ttcaagtgta atatctgacg
    17941 cttgtgccac ttctttactg tgagttacga caatcacaca tttacctgtt ttctgggcaa
    18001 gtgatttgag tagttcgaca atatctccag cagttttagg atccagattt cctgttggct
    18061 catcagctag aataactgga gcttctgaga ccaaactgcg agcaatggca acacgttgct
    18121 gttgaccacc tgataactgg agaacattcc gcttgatctg gctttcatcc aaaccaagct
    18181 caagaagtgt attcttgctt gcctttttgt tgaccaatcg gatattttcc agcggagaaa
    18241 gataatctat caagttataa ttttgaaaga ccagggaaat atggtgcatg cgatggtaag
    18301 aatagccctt cttacgaata tcctctcctt gaaaaaggat agaaccttca acaggactat
    18361 ctagaccagc aagtagggac aagagtgtgg attttcctgc tcctgactcc ccaataatac
    18421 tgtaaaattt tccgggttca aaattataat cgatctgata taggactgct tcagcagtat
    18481 tcttataacg gtaggtaaca tcttgtaatt gtaataaagt catgatttct ccttcttaac
    18541 taatagatga taaaatttct ttcggtgatt ttctaaataa gaataggaaa caaagggcta
    18601 cagataagca actaagcaga actagaaaaa cataggattc tgcaaaagat aagatgctag
    18661 ttgataaact gcttgctttg gctagtgtat cttgtaagct tacctgatct ccacttgcta
    18721 gtagagtttg gagtaggtaa gttgtgattc cgtttcctgc aacaaatgct ggaagcaaag
    18781 ctccaagaga taccaaaact acctctaaac agaattgtag gaagatcgag ctcttgcctt
    18841 ttccaagtgc aagtaaaatc cccacttcat agacccgttc tctcaaccag agagacaaaa
    18901 ccagaattaa ggctccagct cctgctatca acatcccata aaggaagatg gtcaggaagg
    18961 tttggaaagt tgcaactgag tctttgattt gttcaaaagc cttgttttcc ttttcgactt
    19021 ggtagccttg attttccaag gccaagtttt ctacctgctt catgagtccg tccatttcct
    19081 taggattttc tacatagaag cgtgctgcac tgacttgagc ttcactattg cccaaaaggg
    19141 tttggctact ttcataatct gtaaagactt gattttcact gaagtcagaa gacaagcctg
    19201 tgaatttctc ttgtttttta ccagaaaaga tgccgataat ctcaaactct actgtttgtc
    19261 cttttccaga ttcagactga ccagcatcca agccaatctt gtcatgaagt gaaagaccgt
    19321 tcttcttagc caattcttcg tggataagga ttttcttgga atcccctttt tgaaggtgtc
    19381 gcccttcttt tagattgaaa gccgaactgg taaaggttac atccttggat gaatcctcaa
    19441 gagccgttaa gctaaccaag ttattgtctg cagctgataa atcatcacgc tccacgctct
    19501 gctcgccagt cactgcttcc ttgtctttta gttttgcgac cgtctcaagt tcaggagaga
    19561 cattttccag ccccttaatc ttgcttacag atgctaggtc tgacaacttg aatgtctgac
    19621 cattctctat cttcttaata gaaaaagatg tattgagtga tttataaaga ttgctttcta
    19681 ctgttttgtt ggacttcatc agagtcaaac aggctgaaat tccggccaat aagaccaata
    19741 aaatcagaaa taaaataaaa cttctcagtc gctttctgct gacataagcc caagatcttt
    19801 ggattggatt catttgtcac ctccatattt gtaagactat tataaaaccc aaatatgaaa
    19861 tgtttatgaa atacgaaaaa aaaaatatcg agtaggggat aatctctagc ccctctcaca
    19921 ccaccgtacg tgccgttcgg catacggcgg ttcaactaac ttttaacgca tgtcgttcaa
    19981 ggtaataatc caaacacgaa accagtccac g
//
LOCUS       DAVDHC010000038        19009 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVDHC010000038 DAVDHC010000000
VERSION     DAVDHC010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19009
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.038"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(105..320)
                     /locus_tag="VUR43_001868"
     CDS             complement(105..320)
                     /locus_tag="VUR43_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413512.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(1191..2441)
                     /gene="ilvA"
                     /locus_tag="VUR43_001869"
     CDS             complement(1191..2441)
                     /gene="ilvA"
                     /locus_tag="VUR43_001869"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET5413513.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2491..2847)
                     /locus_tag="VUR43_001870"
     CDS             complement(2491..2847)
                     /locus_tag="VUR43_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET5413514.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(3085..3321)
                     /locus_tag="VUR43_001871"
     CDS             complement(3085..3321)
                     /locus_tag="VUR43_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413515.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3428..4450)
                     /gene="ilvC"
                     /locus_tag="VUR43_001872"
     CDS             complement(3428..4450)
                     /gene="ilvC"
                     /locus_tag="VUR43_001872"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET5413516.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILVPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4516..4992)
                     /gene="ilvN"
                     /locus_tag="VUR43_001873"
     CDS             complement(4516..4992)
                     /gene="ilvN"
                     /locus_tag="VUR43_001873"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET5413517.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4985..6685)
                     /locus_tag="VUR43_001874"
     CDS             complement(4985..6685)
                     /locus_tag="VUR43_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET5413518.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYLPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6886..8553)
                     /locus_tag="VUR43_001875"
     CDS             complement(6886..8553)
                     /locus_tag="VUR43_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET5413519.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLTDIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8556..8921)
                     /locus_tag="VUR43_001876"
     CDS             complement(8556..8921)
                     /locus_tag="VUR43_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET5413520.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(9078..9266)
                     /locus_tag="VUR43_001877"
     CDS             complement(9078..9266)
                     /locus_tag="VUR43_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET5413521.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(9382..9558)
                     /locus_tag="VUR43_001878"
     CDS             complement(9382..9558)
                     /locus_tag="VUR43_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET5413522.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(9669..9866)
                     /locus_tag="VUR43_001879"
     CDS             complement(9669..9866)
                     /locus_tag="VUR43_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET5413523.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            complement(10121..11665)
                     /locus_tag="VUR43_001880"
     CDS             complement(10121..11665)
                     /locus_tag="VUR43_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET5413524.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            11878..12180
                     /gene="gatC"
                     /locus_tag="VUR43_001881"
     CDS             11878..12180
                     /gene="gatC"
                     /locus_tag="VUR43_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET5413525.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVVEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            12180..13646
                     /gene="gatA"
                     /locus_tag="VUR43_001882"
     CDS             12180..13646
                     /gene="gatA"
                     /locus_tag="VUR43_001882"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET5413526.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLNSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13646..15088
                     /gene="gatB"
                     /locus_tag="VUR43_001883"
     CDS             13646..15088
                     /gene="gatB"
                     /locus_tag="VUR43_001883"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET5413527.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGIPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEIAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGIVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            15212..16255
                     /locus_tag="VUR43_001884"
     CDS             15212..16255
                     /locus_tag="VUR43_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET5413528.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHIIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVNKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            complement(16391..16474)
                     /locus_tag="VUR43_001885"
                     /pseudo
     CDS             complement(16391..16474)
                     /locus_tag="VUR43_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            16633..17193
                     /gene="efp"
                     /locus_tag="VUR43_001886"
     CDS             16633..17193
                     /gene="efp"
                     /locus_tag="VUR43_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET5413529.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            17215..17604
                     /locus_tag="VUR43_001887"
     CDS             17215..17604
                     /locus_tag="VUR43_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET5413530.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            17597..18019
                     /gene="nusB"
                     /locus_tag="VUR43_001888"
     CDS             17597..18019
                     /gene="nusB"
                     /locus_tag="VUR43_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET5413531.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(18066..18443)
                     /locus_tag="VUR43_001889"
     CDS             complement(18066..18443)
                     /locus_tag="VUR43_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5413532.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSYRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(18806..18991)
                     /gene="briC"
                     /locus_tag="VUR43_001890"
     CDS             complement(18806..18991)
                     /gene="briC"
                     /locus_tag="VUR43_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET5413533.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
BASE COUNT         5654 a         4234 c         3446 g         5675 t
ORIGIN      
        1 aaaaggctgc atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag gcagattctc
       61 tatctctact acttgaaggt caagaatccg ccgttatcca aagattaatc ttcaaatttt
      121 tcataatttt tttcatagaa atcaattagg cctagggctg tttcaaatga aatatttttt
      181 acttttgcac gaccctgcgc cagagcaatg atagacattt cacgcgcatt cgtttcttta
      241 gagatacggt agcctgtgat tttcttatca cgaacccagc caacaactga ttctactttt
      301 tcaaagtttg acttagccat gtttttctcc tattttcttc tttataatat ttaattgtat
      361 acgtttttac tacttttgtc aataaaaaaa acatatattc aacgaaaata attagttcag
      421 aattttctta cttccttttt aaatccgata atatataggt tttgctagcc tctacaccat
      481 aaatatttgc taataaaaat actgtattat taccctctta aggtgcgaaa ttattcaagt
      541 tcttaaaaaa tgcttctcta tttccgtaag atagcttatt tcttcgattt aagaactgaa
      601 gatgatagtt ctaaccttta gaaatccaag ccttcactag ctcaaaaact cctatctttc
      661 ttcctcaata aatcatctga gagataggta ttccttatgt ccttcaaatt catcactcct
      721 ttggatattg aggtgctagc ctagaagcag acacccgatt atctaaacca tccttaataa
      781 agatgacaag acagataagc tcagttaatt acttatatat ctttttaata tggtatattt
      841 gtcaacaaaa agaaatcaaa tcatacctta tactcaatga aaatcaaaga gcaaactagg
      901 aagctagccg caagttgctc aaaacactgt tttgaggttg cagatagagc taacgtggtt
      961 tgaagagatt ttcgaagagt attaaagaca gtgtgactat gcttgtcaat agataggaaa
     1021 tcaaaatgaa ggatggaaat ctgagccaaa catcataagt gctataatga acagaagtaa
     1081 gaattgcacg ataagttttc taaaaccata ggaatcgtcc cctttcttca tcttcattat
     1141 agcacatata catcagttgt acaaataata tgatattttt ttattagtcc tcagacaagc
     1201 atattataaa gcgtttcatt accatttaag ttaatataag ctggatcaaa accttccatt
     1261 ctacgaatca aacctgcata atcatgctta tctgctaaag cgatcccaat taatactggg
     1321 cctgttccct tgctagctcg tttgatatac tcaaaacgtg tgatatcatc atttggcccc
     1381 aggatatcat ttacaaactc acgcaaagct cctggacgtt gtgggaaatt gaccacaaag
     1441 taatgtttga taccatcata aatcaaggca cgctcttcca tttctggcat acggttgata
     1501 tcattatttc ctccagaaat gatacaacaa atggttttcc ccttaatata ttcagctaaa
     1561 acctctaaag aggcgatact agccgctcca gcaggttctg cgactatccc ttgcttagag
     1621 taaaggtcaa tcaaggtttc agaaatcaat ccctcatcga cacctaccaa agtttgaata
     1681 tgttgacgag ttgcttcata ggtcaactga cctacctttt gcacagcaat cccatccgca
     1741 aatttatcaa tttccttgag ttttactgga cctccagcct caaaggcagc tttcatggaa
     1801 cgcgctccat tcgcctctac tccgataacc tcaatctctg gacttgtttc cttgatatag
     1861 gtagaaaccc cggcaatgag accgccacca ccaacaggaa ccaagacagc atcaaaatca
     1921 atcgattctt ttcgagcttc ttctaaaatc tcataagcaa ctgttccttg acctgcttga
     1981 acatgagcat catcaaaagg atcaataaag gtacgatttt cagagactgt aaattcttga
     2041 gctgctttgg ctgaggcatc aaaggtatct ccaactagtt taatagttac aaaatcccca
     2101 ccaaaaaagc gaacctgacc aatcttttgt tgtggcgtag taataggcat aaagatagta
     2161 gcaggaattt tcatttcatt acaagtatag gctactccct gcgcatgatt tcccgcagaa
     2221 gcgcagacta ccccacgttc acgttcttcc ttgctgagct gggaaatggc ataataggca
     2281 ccacgaattt taaaggagcg aacacgctgg gcattttctt ttttcaaata aatcttagca
     2341 ccatacttct ccgataaata atgatcgtaa tccagtggag tattcacaac cacaccgttc
     2401 aagaccttgt gagccttgat tatatctttt gaacttaaca tataaaacct ctttttctat
     2461 aaaaaacagt cactaatgac tgttttttag ttattcatct ccgaaaactt cagtaacact
     2521 ttcatggtat ttatgagcca tacgaatcga aaactcttta ggaagttcat aacgatttgt
     2581 ggaaatccaa tcatataacc attctaccaa actttcttca ctatcattac gatggaagat
     2641 aaaatagttt aaaatttctt tatattctac atcattcaaa tccaacgtgt ctacaaattg
     2701 actacgagga acaaaattag aatctaattt tcttagttga tctgtcaatt ctcccaattg
     2761 taaatccaac tgaaaaaata gtttttgcag ttgcctatca gtttcatcac atcctgtctt
     2821 gatagaaaac aaattggtaa tattcatatg atttcaaccc ctaaataagt acatctaata
     2881 tcccacgaat agctgaagct aaagttttcg cagtccagtc atttaaaccc gattctttca
     2941 atccagatgc aataatttgc tctatttgat ataaaccgcc atctatcgtc tcatttattc
     3001 tgcgaagagg accttcaata taggataaag cttctccgaa tctaacagct gatttaggtc
     3061 ctaatgattt accaactata tttgttaatg ttttttattt ctcaaaatcc atttcgctat
     3121 ataacgagca gatttagtcg cgccagctct ctcaaacgga gaatgaattt caagaccttc
     3181 ttctctagct atttgtgcca atttgaagaa ttgttcaaag gtcatatgca acctaccatc
     3241 ttcaaaatta gcatcatcat aaatgttaat tacagcattt tcatcatacg accaatctgc
     3301 tttattttgg tctgctagca ctattaccga cggtgtaatt acattataca actagaacca
     3361 ataataacga tgcaattttt ctcataatct ttttcataaa atcatctcca gcgctatata
     3421 tttctaatta gttatagatt ttgaatgcat catcgtcgtt tttaccaacg aatggcattg
     3481 ctttacgcaa ttctgcacca actttttcaa tttcaaggtt agctgcttgt tcacggtaag
     3541 cagtcaattt tggacgtcca gctttatagt catttacaaa gtcatttgca aatttaccat
     3601 tttggatgtc tgccaagaca gccttcatat tttctttaac ttgttcagtg attacacgtg
     3661 gacctgatac atagtcaccg tattcagcag tgtttgaaat agattgacgc attttcttga
     3721 atccaccttc gtagatcaag tcaacgatca atttcatttc gtgaagaact tcaaagtaag
     3781 ccaattctgg agcgtaacct gcttctgtca agacttcgaa acctgcttcg ataagggcag
     3841 tcaaaccacc acaaagtaca gcttgttcac caaacaaatc ttcttcagtt tcttctttgt
     3901 aagttgtttc aagaagacct acacgagccg ctccaacacc tttacaccag tccatagcaa
     3961 tgtttttagc atttcctgtt gcatcttggt atactgcata aagagctgga acaccaaatc
     4021 cttcttcgta agtacgacgt accaagtgtc ctggtccttt aggagcacac atgaagacat
     4081 ctacatccgc gggaactttg ataaattcaa agtggatgtt gaaaccatgg gcaaatccaa
     4141 ctgcgtttcc agcttccaag tttggagcga tttctgcttc gtacaattct tgttgaattt
     4201 cgtctggcac caagatcatg ataacatcag ccaacttagt agcttctgct actgtgtaag
     4261 tatcaaatcc atcttctttt gctttatcaa aagatttacc tggacgtaca cctataataa
     4321 cgtcacgacc tgaatcacgc aagttttgag catgcgcatg cccttgtgaa ccataaccga
     4381 taacggcgat ttttttaccg tcaagtgctg ctactttaac atctttttca tattccattt
     4441 gaactgtcat agcttttctc tcttttctat tatttattgc cttttaggct ggtttaataa
     4501 atttaagttg gatttttaat cgcgggtaaa tccagttgca cccgttcgag caatattgcg
     4561 aataccgtat gggcgaatga ctcgcaatag ggcttcgctc ttttctgcat ttcccgtcat
     4621 ctgaatggta atcgagcttg gcgctacgtc taccactgtt gcacggaaag gttgaataat
     4681 cgctaaaatc tcagctctct tctcagctgg cgctgacatc ttaaccaaaa tcacctcgcg
     4741 ctccaaatga ggcttgtctg taatatctcg aatgcgaatc acatcaatct gacgattgag
     4801 ctgtttgatg atttgctcca cttcatcatg agaagcaaca tcaataataa tagtgatacg
     4861 cgatacattc ggatcttctg ttgctccaac agagatgctt tcaatattaa cctgacgacg
     4921 agataggaca cctgtaaagc gattgaggac tcctgaacga ttttgtaatt ttgctgttaa
     4981 cattctacgc atggaactgc acccccaaca tctcatgatt actcttacca gccggtacca
     5041 ttggtaacac ctgttcctta cgagaaatat ctacctcaat tagcatagga acatcctcag
     5101 tgatgacttc aaggtcttga gccaaggtct caggattgtc aaacttatag tttttaatac
     5161 cataagcctg cgccatcaat tggaaatcag gaagggtatc aaagaccgac tctgatgttc
     5221 tgccttcata gaaggattcc tgccactggc gaaccattcc aagtgaatga ttgttcagca
     5281 taaccacctt gattggcacc ttgtaaatat tcaaaatagc caactcctgg ttggtcattt
     5341 ggaaaccacc atccccaaca aacaagacta cttccttatc tgggttagca attttagcac
     5401 cgattgctgc tggaattcca aagcccattg ttcccaaacc acctgaagtc actaactgac
     5461 gctcattttg gtagggataa tactgagctg tccacatttg gtgttgacca acgtctgtta
     5521 ccacaatggc atctccattc gtcaattcac caattcgttc aataactgct tgcggttgaa
     5581 ccacacgctc tttcttgtca taagaacgaa cacgattctt gtctttagtg actttctcaa
     5641 tccacttttc agtattgttg tgaactgttg gttctgctag caacatttgc aaggccttct
     5701 tagcatctcc aactacagga atgtctgcac tgataatctt gccaatctca gctgggtcaa
     5761 tatcaatgtg ggcaacctta gcattcttag cgaaagtctt aggattcccc gtcaaacggt
     5821 catcgaaacg agaaccaata ctaatcataa agtccgcttc cgtcatggca atatttgctg
     5881 cgaatgaccc gtgcatgcct cccattccaa gaaagagtgg gtgactcgtt gcaatcgttc
     5941 cttgtcccaa aagactggtt accactggaa tttgatagcg ttctgcaaat tcatttagtt
     6001 ccgtagcagc ctcagcataa ctaattccac caccagctaa caagactggc tttttagcct
     6061 tggacaattg cttcaagatt ttcttgattt gcatatcatt cggctcaaga gtcggctgat
     6121 aacttggtaa attcacttct ggtaaataaa tgaagtctgt ttctaaagca gatatgtctt
     6181 ttggtaggtc aattacaact ggccctggac ggcctgtagt tgcgatatgg acagcttccg
     6241 tgatgatacg cggaatatca gctgtctcac gaacttggta attgtactta gtgattggca
     6301 tggtaattcc cacgatgtct gcctcctgaa aggcatcctt cccaatccct gctcgcgcca
     6361 cctgacctgt aaagaccaaa aggggaacgc tatcgctcat ggcatccgca atccctgtaa
     6421 tggcatttgt tgctcctggt ccactagtga caacggcaac acccaacttt ccagttgatt
     6481 tggcataacc ttcagcttca tgcaaacaac cttgctcatg gcgccctaga atgtggcgaa
     6541 tgcctttaaa attatatatc gcatcataaa aaggcaaaac cgcaccacca ggataaccaa
     6601 agatggtatc aactcctaaa tcacgaagtg tttccaaaac taggtccgac cccgtcttag
     6661 gagattctaa actgattttc tccattgttc ccctttcttt cctcttaaaa ataacttgtt
     6721 actatcatac cattttttca aaatttttca agataaaaga agaaattttc tgaattttct
     6781 attttaacgt ttatttatga atattatttt tatttttatt aaaaagatac cgatttcatt
     6841 tactaaaaaa gaaaaaagaa ctgatttctc agtccttcat taatcttatt ccacactaaa
     6901 taggtatggg taaacaggtt gttgaccttg gtgaatctcg acttcaacgt cttcgaattc
     6961 ttctacgatt tcttgagcga tttcattggc aagttcttcg cttccgtctt caccgacata
     7021 gaaggttacg atttcactgt cttcatccaa catatgtttc aaggtttcag tcaatgtttg
     7081 gtgcatatca gggtttgaca caagaatttt tccatccacc atacctagat tatcgttttc
     7141 atggatttct aagccatcga tcgttgtatc acgcacggct gttgtgacgc ttccgctaac
     7201 gacatcgcta agagcagctg tcatacgctc ttggttttct tcaatggact tgcttggatc
     7261 aaaggcaaga agacttgtca taccttgagg aagagtgcga gcctctacca ctactgctgg
     7321 ttgctccaaa acttctgccg cagattgagc tgccatgaag atgttcttgt tgtttggcaa
     7381 gaagatgatg ttacgggcat tgacctgttc aacagccttg ataaagtctt ctgttgaagg
     7441 gttcatggtt tgaccgcctt cgataacata gtccacgcct tgagaacaga agatatctgt
     7501 tagaccttta ccagccacca cagcaattaa agcatactct ttttcttcag ccgacttgat
     7561 aacttgagta gcttctttct caacctgtgc ttcgtgttgg ttacgcatat tgtcaacttt
     7621 taccttgacc aagctaccat atttgagacc ttcttgcata acaagtcctg gatcttctgt
     7681 atgaacatgg actttgacaa tttcatcatc gttaacaacg aggagagaat ccccaagctc
     7741 atccaagtag ttacggaatt catcgtaatc aaaatcttta gcataggttg gaccttgctt
     7801 aagagctacc atgatttcag tacagtaacc aaacgtgatg tcctcagtcg ctacgtgacc
     7861 agctacagac ttatgatgct ctacattgat catctcactc atgttggcag gagtcgctac
     7921 aaagtcctca gatgcaatat attcgccagt aagggctgaa aggaaacctt cgtagatgaa
     7981 gaccaatcct tgaccacctg agtccacaac gccaacttct ttcaatactg gaagcatgtc
     8041 tggtgtttta gctagagctg ttttagcacc ttccaaggct gcgcgcatga cttcaacagt
     8101 gtcatctgtt tgctcagctt ttttcttagc accgatagca gctccacgag aaactgtcaa
     8161 aatcgttcct tcaacaggtt tcatcactgc cttataggca acttccacac ctgattggaa
     8221 ggccagagcc aagtcttgac ctgttaactc gtctttatcc ttgatagctt gggaaaatcc
     8281 acggaaaagc tgagacgtaa tcactcctga gttcccacgc gcacccatca aaagcccttt
     8341 ggcaagaatg ctcgctactt ctccaactgt agaagctggc ttgtctgcaa cttctttagc
     8401 accattttca atggtcattc ccatatttgt cccagtatct ccatctggaa ctggaaagac
     8461 gtttaatgaa ttgacatatt cagcttgctt attcaagcga gttgatgcag cctgcaccat
     8521 ttcttgaaat aagctagtag taatttttga cacggttatt ctcctacaac tttgatattt
     8581 tgaatgtaga catttacagt ctgagcagta attccaagct ggttttccaa gctaaaggca
     8641 acacgctctt gaatgttttt tgacacttca ctaatctttg ttccgtagct taacacggta
     8701 tatacatcaa ctgcaatact gccatcttcg gctgccttta cgacgacacc tttagaataa
     8761 ttttccttac ctagcagggc ttggaaatta tctttgaggg catttttact agccataccg
     8821 accacaccaa aaatctcagt tgctgctcca cctacgacgg ttgcaatcac ttcatctgtt
     8881 agttcgattt gaccatcttt tgtattaatt tttacagtca tcctttttac ctcaactagt
     8941 tgatactcta ttttatcata tttcagccca agtgtaaaag cagaatgatg tatcagcgga
     9001 tatttactct atttttcaaa cgatgttata cccacaataa aagaaaaaag accctaaggt
     9061 ctcctttgct tttattatta aacgcgttca actttacctg atttcaaagc acgagctgaa
     9121 gcccaaactt ttttaggttt accatcgata agaacagtaa ctttttgaag gtttggtttt
     9181 acggcacgtt ttgtttggtt catcgcgtgt gaacggttgt ttcctgatac agtcttacga
     9241 cctgtaaagt aacatacttt agccattgtg ttttcctcct attagatcta atatagcgga
     9301 tatgctagca ccacataccg tactatgtta tcacactttc ttgttttttg caagggaatt
     9361 ggaagatttt ttatttgtgt cttaaatcag gtcttgcgtg acattttctg ctctccacat
     9421 gccatcgttg attaacagaa caccagaatt aaaattatgt gtataaaaat catctctaac
     9481 tgcagctaag ggtatagccg tcaagtccaa atcccacagc tcatctatcg attttcttac
     9541 aacaatatct gaatccaaat acagtacacg agactcgctt acatactttg gaataaaata
     9601 cctaaaaaag ccgcatatga aagtccctca aaggggagac gataaccttt cagaatacta
     9661 ctgtcaatct aaacattcac aatctcacta ttcaaagtct ctagtctttt ttccattaat
     9721 tggaaccatt ctcgcggaag gtcatcatta aaaacataaa acttaagatt ataatgatga
     9781 acacaaagag attttattgt tgtttcaact ttatccatat aagcattatc tgcacctaag
     9841 acaatcgctt ttttctcttc tttcactttt tatctcattt ctttttattc ccatcatatg
     9901 tttctacgta accattattt tcgcctattc gttcgtaaaa ccataccagt ggagatttta
     9961 gatgaagtcc cattacggtt tacaattttt acattacgac acagagtttt acaaatcgat
    10021 ttcatttgcc aaacgtagtt agtgaggcag ttagctagtt cgccaaatag cgactagcgt
    10081 ccaacaattt ggaactttag ttccaattgt tggtactgag tcacatcttc tcctctaact
    10141 ctacgtctgg atacttgtcc gcaaaccagc ggagggcaaa gtcattttca aagagaaaga
    10201 ctggttggtc aaaacggtct ttggctaaga tattgcgact tgacgacatc cgttcatcca
    10261 agtcctcagg cttgatccaa cgaacggtct ttttacccat tgggctcatg accacttccg
    10321 cattgtattc gccttccata cggtgtttaa agacttcaaa ctggagttga ccaacagcgc
    10381 ctagcatgta ctcacctgtt tggtaattct tataaagctg aacggctcct tcttgcacca
    10441 attgctcaat ccccttgtgg aaggattttt gcttcataac attcttagca gaaactttca
    10501 tgaaaatttc aggagtaaag gttggcagtg gttcaaattc aaacttgttt tttccaaccg
    10561 tcaaggtatc cccaacctga taagtaccgg tatcgtaaac cccgataata tcacctgcca
    10621 cggcattggt cacattctca cgactctccg ccataaactg ggtaacatta gatagtttag
    10681 cccccttacc agtacgaggg agattgacac tcatgccgcg ctcaaattcg cctgatacga
    10741 tacggacaaa ggcaatacgg tcacggtgac gaggatccat gttggcttgg attttaaaga
    10801 caaagcctga gaaatccttg tcataaggat ccacaatttc accgtctgtt ttcttgtgac
    10861 catgtggttc tggagcaaac ttgaggaagg tttcaaggaa ggtctgcaca ccaaagtttg
    10921 tcagggctga accgaaaaag acaggcgtca attctccagc caaaatagct tcctctgaaa
    10981 actcattccc ggcttcattt aaaagctcaa tgtcatcctt gacttgctcg tagaaaggat
    11041 tgctaccaaa gagtttgtcc ccgtcttcta gactggcaaa acgctcatcc cctttgtaaa
    11101 gctctaaacg ttggttatag aggtcataca agccctcaaa ggctttcccc atcccgatag
    11161 gccagttcat agggtagcta gcaatgccca agatttcttc caattcttgc aacagatcca
    11221 aaggctcacg accgtcacgg tccagcttgt tcataaaggt aaagactgga atgccacgat
    11281 gtttcacaac ctcaaacaat ttcttggttt gagcctcgat ccccttggca gagtccacga
    11341 ccatgaccgc agcatccacc gccatcaagg tacgataggt atcttctgag aagtcctcgt
    11401 gccctggcgt gtctaagata ttcacgcgct tgccgtcgta gtcaaattgc ataacagatg
    11461 aagtaacaga aatcccacgt tgcttctcga tatccatcca gtcagattta gcaaaagtcc
    11521 ctgttttctt cccttttacc gtaccagcct cacgaatctc acccccaaag tagagtaact
    11581 gctcagtgat ggttgttttc cccgcgtccg ggtgggaaat aatggcaaag gtacgacgtt
    11641 tcttaatttc ttcttgaata ttcataagtt ctctttcttt gattctctat ttttcttgtt
    11701 tcaatagctg agaatgattt ttacattgga ttttaccatt cctttcaaca ctccattata
    11761 tcggatttta gcattttttt caatttctat ttcttttcac ttccccctcc cttatttata
    11821 ggaaaatatg gtaaaataga acagactaaa aatcatcatt tcacgaaagg atgcaagatg
    11881 aaaattacgc aagaagaggt aacacacgtt gccaatcttt caaaattaag attctctgaa
    11941 gaagaaactg ctgcctttgc gaccaccttg tctaagattg ttgacatggt tgaattgctg
    12001 ggcgaagttg acacaactgg tgtcgcacct actacgacta tggctgaccg caagactgta
    12061 ctccgccctg atgtggtcga agaaggaaca gaccgtgatc gcttgtttaa aaacgtacct
    12121 gaacaagaca actactatat caaagtgcca gctatcctag acgatggagg agatgcctaa
    12181 tgacttttaa caataaaact attgaagagt tgcacaatct ccttgtctct aaggaaattt
    12241 ctgcaacaga attgacccaa gcaacacttg aaaatatcaa gtctcgtgag gaagccctca
    12301 attcatttgt caccatcgct gaggagcaag ctcttgttca agctaaagcc attgatgaag
    12361 ctggaattga tgctgacaat gtcctttcag gaattccact tgctgttaag gataacatct
    12421 ctacagacgg tattctcaca actgctgcct caaaaatgct ctacaactat gagccaatct
    12481 ttgatgcgac agctgttgcc aatgcaaaaa ccaagggcat gattgtcgtt ggaaagacca
    12541 acatggacga atttgctatg ggtggttcag gtgaaacttc acactacgga gcaactaaaa
    12601 acgcttggga ccacagcaag gttcctggtg ggtcatcaag tggttctgcc gcagctgtag
    12661 cctcaggaca agttcgcttg tcacttggtt ctgatactgg tggttccatc cgccaacctg
    12721 ctgccttcaa cggaatcgtt ggtctcaaac caacctacgg aacagtttca cgtttcggtc
    12781 tcattgcctt tggtagctca ttagaccaga ttggaccttt tgctcctact gttaaggaaa
    12841 atgccctctt actcaacgct attgccagcg aagatgctaa agactctact tctgctcctg
    12901 tccgcatcgc cgactttact tcaaaaatcg gccaagacat caagggcatg aaaattgctt
    12961 tgcctaagga atacctaggc gaaggaattg atccagaggt taaggaaaca atcttaaacg
    13021 cggccaaaca ctttgaaaaa ttgggtgcta tcgtcgaaga agtcagcctt cctcactcta
    13081 aatacggtgt tgccgtttat tacatcatcg cttcatcaga agcttcatca aacttgcaac
    13141 gttttgacgg tatccgttac ggctaccgcg cagaagatgc gactaatctt gatgaaatct
    13201 atgtaaacag ccgtagccaa ggttttggtg aagaagtgaa gcgccgtatc atgctgggta
    13261 ctttcagtct ttcatcaggt tactacgatg cctactacaa gaaggctgga caggtccgta
    13321 cacttatcat tcaagatttc gaaaaagtct tcgcggatta tgatttgatt ttgggtccaa
    13381 ctgctccaag tgttgcctat gacttgaatt ctctcaacca tgacccagtt gccatgtact
    13441 tagccgacct attgaccata cctgtaaact tggcaggact gcctggaatt tcgattcctg
    13501 ctggattctc tcaaggtcta cctgtcggac tccaattgat tggtcccaag tactctgagg
    13561 aaaccattta ccaagctgct gctgcttttg aagcaacaac agactaccac aaacaacaac
    13621 ccgtgatttt tggaggtgac aactaatgaa ctttgaaaca gtcatcggac ttgaagtcca
    13681 cgtagagctc aacaccaatt caaaaatctt ctcacctact tctgcccact tcggaaatga
    13741 tcaaaacgcc aacactaacg tgattgactg gtctttccca ggagttctgc cagttctcaa
    13801 taaaggggtt gtcgatgccg gaatcaaggc tgctcttgcc ctcaacatgg acatccacaa
    13861 aaagatgcac tttgaccgca agaactactt ctaccctgat aaccccaaag cctaccaaat
    13921 ttctcaattt gatgaaccaa tcggatataa tggctggatt gaagtcgaac tagaagacgg
    13981 tacgaccaag aaaatcggta tcgaacgtgc ccacctagag gaagacgctg gtaaaaacac
    14041 ccacggtaca gacggctact cttacgttga ccttaaccgc caagggatac ctttgattga
    14101 gattgtatct gaagccgata tgcgttcgcc agaggaggcc tatgcttatc tgacagccct
    14161 caaggaagtt atccagtacg ctggcatttc tgacgttaag atggaagaag gttctatgcg
    14221 tgtggatgcc aacatctccc ttcgccctta tggtcaagaa aaattcggta ccaagactga
    14281 attgaagaac ctcaactcct tctcaaacgt tcgtaaaggt cttgaatacg aagtccaacg
    14341 ccaggctgaa attcttcgct caggtggtca aatccgccaa gaaacacgcc gttacgatga
    14401 agcgaataaa gcaaccattc tcatgcgtgt caaggaaggg gctgcagact accgctactt
    14461 cccagaacca gacctacccc tctttgaaat ttctgacgag tggattgagg aaatgcggac
    14521 tgagttgcca gagtttccaa aagaacgtcg tgcgcgttat gtatctgacc ttggtttatc
    14581 agactacgat gctagtcagt tgactgctaa taaagtcact tctgacttct ttgaaaaagc
    14641 tgttgcccta ggtggtgatg ccaaacaagt ctctaactgg ctccaagggg aaatcgctca
    14701 gttcttgaat gctgaaggta aaacactgga acaaatcgaa ttaacaccag aaaacttggt
    14761 tgaaatgatt gccatcatcg aagacggtac tatttcatct aagattgcca agaaagtctt
    14821 tgtccatcta gctaaaaatg gcggtggcgc gcgtgaatac gtggaaaaag caggtatagt
    14881 tcaaatttca gatccagcta tcttgatccc aatcatccac caagtctttg ccgataacga
    14941 agctgctgtt gccgacttca agtcaggcaa acgtaacgcc gacaaggcct ttacaggatt
    15001 ccttatgaag gcaaccaaag gccaagccaa cccacaagtt gcccttaaac tacttgcaca
    15061 ggaattggcg aagttgaaag aaaactagac agaacaaaac cagccctaag gttggttttt
    15121 tcttgacaaa tagaaagaaa gcgtttacaa tattgcgtgt aaagtttcca aacaagaaaa
    15181 ctaaaaatcg caacaataag gagttattta tatggctaca atgaaggcag ctcgctggca
    15241 tgcagcgaaa gatgttcgta ttcaagaaat agaagttcct gaagtacttc cgcaccaagt
    15301 aaaagttgca gttaagttca caggaatttg tggtactgac ctccatgaat ttttagatgg
    15361 acctatcttt atcccaacag atgagcacgt ctattctggt caaaaagcac cggtaacact
    15421 gggacatgaa ttttctggtg aaatcataga agtcggaagc gatgttaccc gtgttaaagt
    15481 tggtgatcgt gttgctgtgg aaccaattct agctaaaaat aacttagttg gtgattataa
    15541 tttggatcca aaccttaatt ttgtcggttt ggctgcagac ggtggatttg ccaaatattg
    15601 tgttttagac ggtgacttag tacatatcat tccagatagc ttgagctatg agcaagctgc
    15661 tcttactgaa cccgctgctg ttgcagtcta tgctgttcgt caatcttctt tgaaggctgg
    15721 cgatacagct gttgtctttg gtttaggccc gattggtcta ttaattgtag aagctcttcg
    15781 tgcagctggt gcttctaaga tttatgctgt tgaactatca cctgaacgtc aagcaaaagc
    15841 tgaagagtta ggagctatcg ttgtccgtcc ggaagaaggt gaaacagctg ttgaagctat
    15901 tcatcgttta acaaacggtg gtgtagatgt ttcttatgaa gtaacgggtg tgccagtagt
    15961 tttaggacaa gccttagctg ccgtaaataa agcaggtgag tgcatggtgg tctctatctg
    16021 ggaacgagaa gcaaatatta atccgaatga atttgcaatc caagaaaaga cactaaaagg
    16081 aatcatcgct tatcgtcata tcttccctaa agtattagaa ttgatggaac aaggctactt
    16141 ctctgctgaa aaattagtta ctaagaaaat taaattggaa aatatcgtcg aagaaggctt
    16201 tatcgaatta actcaagata agtcacaaat taaaattttg gtagaaccag aataaaaaat
    16261 caatcttttt aagacaatac taacaggtcg gagtaaactt acttcggcct tttgaaatat
    16321 aatactcttc gaaaatctct tcaaaccacg tcagcgtcac attaccgtat atatggttac
    16381 tgacttcgtc agttctatcc acaacctcaa aacagtgttt tgagcagcct gcggctagct
    16441 tcctagtttg ctctttgatt tccattgagt atgagaagaa atatagtgga tactctttaa
    16501 cattaaccac tccacctgac tagccaatat tctttttcgc tcctaccaac tcccaataac
    16561 tattttggct ttatttccag agtattttat ggtaaaatga agagtaataa tatttattaa
    16621 agaggtaaaa acatgattga agcaagtaaa ttaaaagctg gtatgacctt tgaaacagct
    16681 gacggcaaat tgattcgcgt tttggaagct agtcaccaca aaccaggtaa aggaaacacg
    16741 atcatgcgta tgaaattacg tgatgtccgt actggttcta catttgacac aagctaccgt
    16801 ccagaggaaa aatttgaaca agctattatc gagactgtcc cagctcaata cttgtacaaa
    16861 atggatgaca cagcatactt catgaataca gaaacttacg accagtacga aatccctgta
    16921 gtcaatgttg aaaacgaatt gctttacatc cttgaaaact ctgatgtgaa aatccaattc
    16981 tacggaactg aagtgatcgg tgtcaccgtt cctactactg ttgagttgac agttgctgaa
    17041 actcaaccat ctatcaaagg tgctactgtt acaggttctg gtaaaccagc aacgatggaa
    17101 actggacttg tcgtaaacgt tccagacttc atcgaagcag gacaaaaact cgttatcaac
    17161 actgcagaag gaacttacgt ttctcgtgcc taatctctag aaagaggtca ttctatggga
    17221 attgaagaac aacttggcga aatcgttatc gccccacgtg tacttgaaaa aatcattgct
    17281 atcgctactg caaaggtaga gggtgttcac tctttttcaa acagatcagt gtctgatacc
    17341 ctttcaaaac tttcactcgg ccgtggcatt tatcttaaaa acgtggacga agaactcaca
    17401 gcagatatct atctctacct tgagtacgga gtaaaagttc ctaaggtagc ggttgctatc
    17461 cagaaagctg tcaaagatgc cgtccgtaat atggctgatg tagaactcgc tgctatcaat
    17521 attcacgttg caggtatcgt cccagataaa acaccaaaac cagaattgaa agatctattt
    17581 gacgaggact tcctcaatga ctagtccact attagaatct agacgccaac tccgtaaatg
    17641 cgcttttcaa gctctcatga gccttgagtt cggtacggat gtcgaaactg cttgtcgttt
    17701 cgcctatact catgatcgtg aagatacgga tgtacaactt ccagcctttt tgatagacct
    17761 cgtttctggt gttcaagcta aaaaggaaga actagataag caaatcactc agcatttaaa
    17821 agcaggttgg accattgaac gcttaacgct cgtggagaga aacctccttc gcttgggagt
    17881 ctttgaaatc acttcatttg acactcctca gctggttgct gttaatgaag ctatcgagct
    17941 tgcaaaggac ttctccgatc aaaaatctgc ccgttttatc aatggactgc tcagccagtt
    18001 tgtaacagaa gaacaataaa aagaaaaagt gtttgatatc tatcaaacac tttttctggc
    18061 tcccactatc taaaaaaatg ataatagata taattgtaaa caaaaatcca gataggtttt
    18121 gcatgattga gaaagttaaa aaaactatgg cagagaatcg ttaatctcag attgtcggta
    18181 gaacgataaa caagggcaaa aaagaaacca atcagactat aatataataa actaattgga
    18241 tctctgtaag atagtatcaa atggctaatc ccaaagataa ggcctgataa gatgacatct
    18301 aaatagtact ttgacttagg aaagaaggta ttcataaaat accctctatc aagagtctcc
    18361 tcaaaaacag gaccgattat tacaagcagg acaaaagata agatagtcga taaaaaggtt
    18421 ggttgtccat ttgaaagaac cacggtaaaa tactcatcat gaatattcct atggttaatc
    18481 aaatgagcat agcgtgccta aaaattaccg agaatctgat aaaccacata agttgcaaat
    18541 aagtagaaga caaatgacca gttccagctc tttttttcaa agataaagag catctttttc
    18601 ttttttaacc tccaaattaa tagaaggaaa cttcccacta ataccattgt taaaataaga
    18661 gaatagacat cagctcctaa ccctaaaatg atcgtcacat acaatccaat tgtttgtggt
    18721 aaataggtag atagtaaaat aataagcaaa aatattccaa attgtcttag tttttttgtg
    18781 tttctcatcg tacttttttg aaagattacc ctgctcggaa gccgtacttc caagcatcta
    18841 tataagaatt aagtgcccct tgcctcatat agggagcaaa ttctctataa tataaccatc
    18901 tactatatcc atcttcccaa acagcaagac cacctgaagt ttgctccaag tcctcagttg
    18961 aaagaactgt aaatgtattt gtacctgtca ttgcaagtac cttcttaaa
//
LOCUS       DAVDHC010000039        18846 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVDHC010000039 DAVDHC010000000
VERSION     DAVDHC010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.039"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(121..972)
                     /gene="srtC-3"
                     /locus_tag="VUR43_001891"
     CDS             complement(121..972)
                     /gene="srtC-3"
                     /locus_tag="VUR43_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-3"
                     /protein_id="HET5413534.1"
                     /translation="MSRTKLRALLGYLLMLVACLIPIYCFGQMVLQSLGQVKGHATFV
                     KSMTTEMYQEQQNHSLAYNQRLASQNRIVDPFLAEGYEVNYQVSDDPDAVYGYLSIPS
                     LEIMEPVYLGADYHHLGMGLAHVDGTPLPLDGTGIRSVIAGHRAEPSHVFFRHLDQLK
                     VGDALYYDNGQEIVEYQMMDTEIILPSEWEKLESVSSKNIMTLITCDPIPTFNKRLLV
                     NFERVAVYQKSDPQTAAVARVAFTKEGQYVSRVATSQWLYRGLVVLAFLGILFVLWKL
                     ARLLRGK"
     gene            complement(959..1852)
                     /gene="srtC-2"
                     /locus_tag="VUR43_001892"
     CDS             complement(959..1852)
                     /gene="srtC-2"
                     /locus_tag="VUR43_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-2"
                     /protein_id="HET5413535.1"
                     /translation="MDNSRRSRKKGTKKKKHPLILLLIFLVGFAVAIYPLVSRYYYRI
                     ESNEVIKEFDETVSQMDKAELEERWRLAQAFNATLKPSEILDPFTEQEKKKGVSEYAN
                     MLKVHERIGYVEIPAIDQEIPMYVGTSEDILQKGAGLLEGASLPVGGKNTHTVITAHR
                     GLPTAELFSQLDKMKKGDIFYLHVLDQVLAYQVDQIVTVEPNDFEPVLIQHGEDYATL
                     LTCTPYMINSHRLLVRGKRIPYTAPIAERNRAVRERGQFWLWLLLGAMAVILLLLYRV
                     YRNRRIVKGLEKQLEGRHVKD"
     gene            complement(1839..2741)
                     /gene="srtC-1"
                     /locus_tag="VUR43_001893"
     CDS             complement(1839..2741)
                     /gene="srtC-1"
                     /locus_tag="VUR43_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus system sortase SrtC-1"
                     /protein_id="HET5413536.1"
                     /translation="MVKTKKQKRNNLLLGVVFFIGMAVMAYPLVSRLYYRVESNQQIA
                     DFDKEKATLDEADIDERMKLAQAFNDSLNNVVSGDPWSEEMKKKGRAEYARMLEIHER
                     MGHVEIPVIDVDLPVYAGTAEEVLQQGAGHLEGTSLPIGGNSTHAVITAHTGLPTAKM
                     FTDLTKLKVGDKFYVHNIKEVMAYQVDQVKVIEPTNFDDLLIVPGHDYVTLLTCTPYM
                     INTHRLLVRGHRIPYVAEVEEEFIAANKLSHLYRYLFYVAVGLIVILLWIIRRLRKKK
                     KQPEKALKALKAARKEVKVEDGQQ"
     gene            complement(3079..4260)
                     /gene="rrgC"
                     /locus_tag="VUR43_001894"
     CDS             complement(3079..4260)
                     /gene="rrgC"
                     /locus_tag="VUR43_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus minor pilin RrgC"
                     /protein_id="HET5413537.1"
                     /translation="MISRIFFVMALCFSLVWGAHAVQAQEDHTLVLQLENYQEVVSQL
                     PSRDGHRLQVWKLDDSYSYDDRVQIVRDLHSWDENKLSSFKKTSFEMTFLENQIEVSH
                     IPNGLYYVRSIIQTDAVSYPAEFLFEMTDQTVEPLVIVAKKTDTMTTKVKLIKVDQDH
                     NRLEGVGFKLVSVARDGSEKEVPLIGEYRYSSSGQVGRTLYTDKNGEIFVTNLPLGNY
                     RFKEVEPLAGYAVTTLDTDVQLVDHQLVTITVVNQKLPRGNVDFMKVDGRTNTSLQGA
                     MFKVMKEESGHYTPVLQNGKEVVVTSGKDGRFRVEGLEYGTYYLWELQAPTGYVQLTS
                     PVSFTIGKDTRKELVTVVKNNKRPRIDVPDTGEETLYILMLVAILLFGSGYYLTKKPN
                     N"
     gene            complement(4307..6241)
                     /locus_tag="VUR43_001895"
     CDS             complement(4307..6241)
                     /locus_tag="VUR43_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HET5413538.1"
                     /translation="MKSINKFLTMLAALLLTASSLFSAATVFAADNVSTAPDAVTKTL
                     TIHKLLLSEDDLKTWDTNGPKGYDGTQSSLKDLTGVVAEEIPNVYFELQKYNLTDGKE
                     KENLKDDSKWTTVHGGLTTKDGLKIETSTLKGVYRIREDRTKTTYVGPNGQVLTGSKA
                     VPALVTLPLVNNNGTVIDAHVFPKNSYNKPVVDKRIADTLNYNDQNGLSIGTKIPYVV
                     NTTIPSNATFATSFWSDEMTEGLTYNEDVTITLNNVAMDQADYEVTKGINGFNLKLTE
                     AGLAKINGKDADQKIQITYSATLNSLAVADIPESNDITYHYGNHQDHGNTPKPTKPNN
                     GQITVTKTWDSQPAPEGVKATVQLVNAKTGEKVGAPVELSENNWTYTWSGLDNSIEYK
                     VEEEYNGYSAEYTVESKGKLGVKNWKDNNPAPINPEEPRVKTYGKKFVKVDQKDTRLE
                     NAQFVVKKADSNKYIAFKSTAQQAADEKAAATAKQKLDAAVAAYTNAADKQAAQALVD
                     QAQQEYNVAYKEAKFGYVEVAGKDEAMVLTSNTDGQFQISGLAAGTYKLEEIKAPEGF
                     AKIDDVEFVVGAGSWNQGEFNYLKDVQKNDATKVVNKKITIPQTGGIGTIIFAVAGAA
                     IMGIAVYAYVKNNKDEDQLA"
     gene            complement(6474..9125)
                     /locus_tag="VUR43_001896"
     CDS             complement(6474..9125)
                     /locus_tag="VUR43_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HET5413539.1"
                     /translation="MKKVRKIFQKAVAGLCCISQLTAFSSIVALAETPETSPAIGKVV
                     IKETGEGGALLGDAVFELKNNTDGTTVSQRTEAQTGEAIFSNIKPGTYTLTEAQPPVG
                     YKPSTKQWTVEVEKNGRTTVQGEQVENREEALSDQYPQTGTYPDVQTPYQIIKVDGSE
                     KNGQHKALNPNPYERVIPEGTLSKRIYQVNNLDDNQYGIELTVSGKTTVETKEASTPL
                     DVVILLDNSNSMSNIRHNHAHRAEKAGEATRALVDKITSNPDNRVALVTYGSTIFDGS
                     EATVEKGVADANGKILNDSALWTFDRTTFTAKTYNYSFLNLTSDPTDIQTIKDRIPSD
                     AEELNKDKLMYQFGATFTQKALMTADDILTKQARPNSKKVIFHITDGVPTMSYPINFK
                     YTGTTQSYRTQLNNFKAKTPNSSGILLEDFVTWSADGEHKIVRGDGESYQMFTKKPVT
                     DQYGVHQILSITSMEQRAKLVSAGYRFYGTDLYLYWRDSILAYPFNSSTDWITNHGDP
                     TTWYYNGNMAQDGYDVFTVGVGVNGDPGTDEATATRFMQSISSSPDNYTNVADPSQIL
                     QELNRYFYTIVNEKKSIENGTITDPMGELIDFQLGADGRFDPADYTLTANDGSSLVNN
                     VPTGGPQNDGGLLKNAKVFYDTTEKRIRVTGLYLGTGEKVTLTYNVRLNDQFVSNKFY
                     DTNGRTTLHPKEVEKNTVRDFPIPKIRDVRKYPEITIPKEKKLGEIEFIKINKNDKKP
                     LRDAVFSLQKQHPDYPDIYGAIDQNGTYQNVRTGEDGKLTFKNLSDGKYRLFENSEPA
                     GYKPVQNKPIVAFQIVNGEVRDVTSIVPQDIPAGYEFTNDKHYITNEPIPPKREYPRT
                     GGIGMLPFYLIGCMMMGGVLLYTRKHP"
     gene            9641..11170
                     /gene="rlrA"
                     /locus_tag="VUR43_001897"
     CDS             9641..11170
                     /gene="rlrA"
                     /locus_tag="VUR43_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-1 pilus transcriptional regulator RlrA"
                     /protein_id="HET5413540.1"
                     /translation="MLNKYIEKRITDKITILNILLDIRSIELDELSTLTSLQSKSLLS
                     ILQELQETFEEELTFNLDTQQVQLIEHHSHQTNYYFHQLYNQSTILKILRFFLLQGNQ
                     SFNEFTQKEYISIATGYRVRQKCGLLLRSVGLDLVKNQVVGPEYRIRFLIALLQFHFG
                     IEIYDLNDGSMDWVTHMIVQSNSQLSHELLEITPDEYVHFSILVALTWKRREFPLEFP
                     ESKEFEKLKNLFMYPILMEHCQTYLEPHANMTFTQEELDYIFLVYCSANSSFSKDKWN
                     QEKKTHTIQLILQHTRGKHLLSKFKNILGNDISNSLSFLTALTFLTRTFLFGLQNLVP
                     YYNYYEHYGIESDKPLYHISKAIVQEWMTEQKIEGVIDQHRLYLFSLYLTETIFSSLP
                     AIPIFIILNNQADVNLIKSIILRNFTDKVASVTGYNILISPPPSEEHLTEPLIIITTK
                     EYLPYVKKQYPKGKHHFLTIALDLHVSQQRLIYQTIVDIRKEAFDKRVAMIAKKAHYL
                     L"
     gene            11435..12703
                     /locus_tag="VUR43_001898"
     CDS             11435..12703
                     /locus_tag="VUR43_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5413541.1"
                     /translation="MEHINHTTLLIGIKDKNITLNKAIQHDTHIEVFATLDYHPPKCK
                     HCKGKQIKYDFQKPSKIPFIEIGGFPSLIHLKKRRFQCKSCRKVTVAETTLVQKNCQI
                     SEMVRQKIAQLLLNREALTHIASKLAISTSTSTSTVYRKLKQFHFQEDYTTLPEILSW
                     DEFSYQKGKLAFIAQDFNTKKIMTILDNRRQTTIRNHFFKYSKEARKKVKVVTVDMSG
                     SYIPLIKKLFPNAKIVLDRFHIVQHMSRALNQTRINIMKQFDDKSLEYRALKYYWKFI
                     LKDSRKLSLKPFYARTFRETLTPRECLKKIFTLVPELKDYYDLYQLLLFHLQEKNTDQ
                     FWGLIQDTLPHLNRTFKTTLSTFICYKNYITNAIELPYSNAKLEATNKLIKDIKRNAF
                     GFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(12761..15085)
                     /gene="pflB"
                     /locus_tag="VUR43_001899"
     CDS             complement(12761..15085)
                     /gene="pflB"
                     /locus_tag="VUR43_001899"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET5413542.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            15478..16539
                     /gene="dinB"
                     /locus_tag="VUR43_001900"
     CDS             15478..16539
                     /gene="dinB"
                     /locus_tag="VUR43_001900"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET5413543.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(16686..17531)
                     /locus_tag="VUR43_001901"
     CDS             complement(16686..17531)
                     /locus_tag="VUR43_001901"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET5413544.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            17787..18736
                     /locus_tag="VUR43_001902"
                     /pseudo
     CDS             17787..18736
                     /locus_tag="VUR43_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT         5600 a         4087 c         3308 g         5851 t
ORIGIN      
        1 ctgaatatca aaaaagaaag gacaaaattt gtcctttctc gagcttagct ttttttcaac
       61 ccactacagt tgacaaagag ccggaaaaag gaacagcctt agctttcctt tcatttcttt
      121 ttatttccct cgtagtaaac gtgctagctt ccacaaaaca aacaggattc ccagaaatgc
      181 cagtaccact agcccacggt acaaccattg agaggttgca acacgcgata catattgtcc
      241 ttctttcgta aaagcaaccc tcgcaactgc agctgtttgt ggatctgatt tttgataaac
      301 agcgactcgt tcaaaattca ctaataagcg tttattaaag gtaggaatcg gatcgcaggt
      361 tatcaaggtc atgatatttt tagagctaac cgattctaat ttttcccatt ccgacggtaa
      421 aataatctct gtgtccatca tctgatattc tacaatttcc tggccattat cataataaag
      481 agcatctcca acttttagct gatccaaatg gcggaaaaag acatggcttg gctctgcacg
      541 gtgcccagca atcactgagc gaatccctgt accatccaga ggcagcggtg taccatccac
      601 atgagccaag cccatcccta aatgatgata atctgctccc aaataaaccg gctccatgat
      661 ttccaaactt ggaatagaca agtaaccata gactgcatca gggtcgtcag acacttggta
      721 attgacctca tatccctccg ccaaaaaagg atctacaatg cgattttgcg aagccaagcg
      781 ttgattgtag gcgagagaat ggttctgttg ttcttggtac atttcagttg tcatggattt
      841 cacaaatgta gcatgacctt tcacctgtcc aagagactgc aacaccatct gtccaaaaca
      901 ataaatagga atcaaacagg ctaccaacat caacaagtat cccaataagg ctcgtagttt
      961 agtccttgac atgacgcccc tccaattgct tttctagtcc tttgacaatc cgtcgattac
     1021 gatacacgcg atacagcaag agaaggatga ccgccatcgc tcctagtaat aaccacaacc
     1081 agaattgccc acgctctctc accgctcgat tccgctctgc aattggtgcc gtatacggaa
     1141 tccgcttccc acgtaccaac agacgatgac tgttaatcat atacggtgta caagtcaaca
     1201 aggtcgcata atcttcccca tgttgaatca agacaggctc aaagtcattc ggctccaccg
     1261 tcactatctg atccacttgg taggccaaca cctgatctaa aacgtgaaga taaaagatat
     1321 cccctttttt catcttatcc aattgactga acaattctgc cgttggcaat cctctgtgag
     1381 cagtgatcac tgtatgggta tttttacctc caacaggcag cgaagcccct tctaacagcc
     1441 ctgccccttt ctgaagaatg tcctcactcg ttccgacata catcggaatt tcctgatcaa
     1501 tcgcaggaat ttccacatag ccaatccgct catggacctt tagcatattg gcatattctg
     1561 agacgccttt ctttttctct tgctctgtaa aaggatcaag aatttcagat ggtttcaagg
     1621 tcgcattgaa ggcttgagcc aagcgccaac gctcctcaag ttctgcctta tccatctggg
     1681 aaaccgtctc atcaaactct ttaataacct cgtttgactc aatacgataa taataacgag
     1741 acaccaatgg atatatcgca acggcgaatc ctactaagaa aatcagaaga aggatcagcg
     1801 gatgtttctt cttttttgtg cctttttttc gtgaacgtct actgttgtcc atcctccacc
     1861 ttcacttcct tccttgctgc tttcagcgcc ttcaaagcct tttccggttg ttttttcttc
     1921 ttgcgcaagc gtcgaataat ccataaaaga atcacaatca aaccaactgc cacataaaac
     1981 aggtagcgat agagatgact gagtttgttt gctgcaataa attcttcctc aacctctgct
     2041 acgtacggta tccgatgccc ccgaaccaat agacgatggg tattgatcat gtatggcgta
     2101 caagtcagca aggtcacata atcatgacct ggtacaatca ataaatcatc aaagttcgtc
     2161 ggctcaatca cctttacttg atccacttga taggccatca cttccttgat attgtgcaca
     2221 taaaacttat ccccaacttt aagtttggtc aaatccgtaa acatcttagc tgttggcaaa
     2281 cctgtatgtg ccgtaatcac cgcatgggtc gaattgcctc cgatcggcag agaagttccc
     2341 tctagatgcc cagccccttg ctgcaatacc tcttcagcag taccagcata aaccggcaaa
     2401 tccacgtcaa taacggggat ttccacatgc cccatccgct catggatttc taacatacgt
     2461 gcatactctg ctcgcccttt tttcttcatt tcttccgacc aaggatcgcc actcactaca
     2521 ttattcaaag agtcattgaa ggcttgtgcc aatttcattc gttcatcaat gtcagcctca
     2581 tccaacgttg ctttttcctt atcaaagtca gcaatttgtt gatttgattc cactcgataa
     2641 tacaagcgag acaccagcgg atacgccatt accgccattc caatgaaaaa taccactcct
     2701 aataggagat tatttcgttt ttgctttttt gtttttacca tttttatcag catcccttta
     2761 tcttcaaact catcatttta tcgcttttcc taacagacaa tcctatctgc taagagaaac
     2821 gagaaaatct catttctttc tgattcacca tccattttaa atcagaatcc cagtcctgtc
     2881 cattcctaaa atgattacca gaccagtcct atcgttttac aaacaataac ccacaatgag
     2941 gctggcacaa tctgcccagc ctcatatccg ttattgtgat tcatgccaca tcaccatgat
     3001 tcctgattaa catcacctca gagtactctg gtcttccctt cagcctgcta tctttttcat
     3061 aatgatgtac attgaatatc agttatttgg ttttttcgta agataataac cactaccaaa
     3121 caacaaaatg gcaacaagca tcaagatata caaggtttct tcccctgtat ctggcacatc
     3181 aatccgtggt cgcttgttat ttttaaccac tgttaccagt tccttacgag tatctttccc
     3241 gattgtaaag gaaacaggcg atgttaattg aacataacca gttggagctt ggagctccca
     3301 taaatagtat gtcccatact ctagaccttc cactcggaaa cgaccatctt tccctgatgt
     3361 tacaactact tccttaccat tttgaagaac aggagtatag tgtccgcttt cttctttcat
     3421 gactttgaac attgcccctt gaagagaggt attggtccga ccatccacct tcataaagtc
     3481 aacattgcca cgtggtaatt tctgattgac aaccgtaatc gtcaccagct gatgatctac
     3541 cagctggaca tccgtatcca gcgtcgtaac agcatagcct gccagtggct ccacctcctt
     3601 gaaacgatag ttcccaagag gaagatttgt cacaaaaatc tctccatttt tatcagtata
     3661 gagagttctc cctacttgac cagaagaact gtaacggtat tctccaatca agggaacctc
     3721 tttttcagaa ccatctcttg ctactgatac caatttaaag ccgacaccct ccaagcgatt
     3781 gtggtcttga tccaccttta tcagcttcac ctttgttgtc attgtatctg tttttttcgc
     3841 tacaatgacc aaaggctcta ccgtttgatc tgtcatttca aaaagaaatt cagctggata
     3901 agaaaccgca tccgtctgga taatagagcg aacatagtaa agaccatttg gaatatgaga
     3961 tacttcaatc tgattctcaa ggaaggtcat ctcaaacgaa gtctttttga aagaagaaag
     4021 tttattctca tcccacgaat gcaagtctct tacaatttgc acccgatcat cataggaata
     4081 cgaatcatcc aacttccata cttgcaaccg atgaccatca cgagatggca attgactaac
     4141 cacctcctga tagttctcca attgcaagac caacgtgtga tcttcttgcg cttggactgc
     4201 atgtgcaccc catacaagag aaaaacacag agccataaca aagaagatac gactaatcat
     4261 tttctgcatt ttctgcattg tcatcaatgg ctcctttctc tcttacttaa gcaagttgat
     4321 cctcatcttt gttgttttta acatatgcgt acactgcaat acccataatc gcagcccccg
     4381 ctacagcaaa gataattgta ccaataccac ccgtttgtgg gatagtgatt tttttgttga
     4441 ctacttttgt agcgtcattc ttttgaacat cttttaagta attaaactca ccttgattcc
     4501 aagaacctgc tccaacaaca aattctacat catcaatttt cgcaaaacct tctggagctt
     4561 taatttcttc taatttataa gtaccagcag caagacctga aatttggaat tgaccatccg
     4621 tattagaagt aagaaccatt gcttcatctt ttccagctac ttcaacataa ccaaatttgg
     4681 cttctttgta agctacattg tattcttgct gtgcttgatc tactagagct tgagcggctt
     4741 gcttatctgc agcatttgtg taagctgcta ccgctgcatc caatttttgt tttgcagttg
     4801 ctgctgcttt ttcatctgca gcttgttgtg cagttgactt aaaggcaata tatttattgc
     4861 tatctgcttt tttaacaacg aactgcgcat tttctagacg agtatctttt tggtctactt
     4921 tgacaaactt tttaccgtat gtttttacac gtggttcttc aggattgatt ggagctgggt
     4981 tattatcttt ccagtttttt acccccaact tccctttgct ctctactgtg tattcagctg
     5041 agtatccatt atattcttct tcaactttgt attcaataga attatctaga ccactccaag
     5101 tatatgtcca attattttct gaaagttcta caggagcacc gactttctca ccagtcttgg
     5161 catttacaag ttgaacagtc gctttcaccc cctcaggagc aggttgactg tcccatgtct
     5221 tagttactgt aatttgacca ttattaggtt tagttggttt tggagtattc ccatgatctt
     5281 gatgatttcc gtaatgatat gtaatatcgt tactttcagg aatgtctgca acagcaagtg
     5341 agttcaaagt agctgagtaa gtaatttgga ttttttggtc tgcatcctta ccattaattt
     5401 tagctaaacc tgcttctgtt aattttaagt taaagccatt aattccttta gtgacttcat
     5461 aatcagcttg atccatagct acattattca aagtaattgt tacatcttca ttataagtta
     5521 gaccttctgt catttcatct gaccaaaatg aagttgcaaa tgttgcatta cttggaattg
     5581 ttgtattaac aacatatggg attttagtac cgatagacag accattttga tcgttataat
     5641 tcaaagtatc agcaattctt ttatctacaa ctggtttatt atatgaattt ttagggaaaa
     5701 catgtgcatc aattactgta ccattattgt taacaagtgg aagagttaca agagcaggta
     5761 cggcttttga acctgttaat acttgcccat taggaccaac ataggtagtc tttgttctat
     5821 cctcacgaat acgatacaca cctttaagag tactggtttc aattttaagt ccatctttag
     5881 ttgtcaaacc accatgaact gttgtccatt tactatcatc tttaagattt tctttttcct
     5941 taccatcagt caaattatac ttttgtaatt caaagtatac atttggaatt tcctcagcta
     6001 caactccagt taaatctttt aaactagatt gagttccatc atatccttta ggaccgtttg
     6061 tatcccaagt ctttaaatca tcttctgaga gcagtaactt atggattgtt aaagttttag
     6121 taacagcatc tggtgctgta ctaacattgt ccgccgcaaa aactgttgca gctgaaaaca
     6181 ggctactcgc tgtcagtaat aaggcagcaa gcattgttaa aaatttgttg attgatttca
     6241 tgatttctcc ttattcatat ctcttaaaat caactgtgag caatgtaatg aattacacat
     6301 gacaataata atcctttttt ctgtgcaagt tttcgaaaac atctcccctt tcaatggtgg
     6361 tttacttggc gaagaaaact gttttcacca agtaaactta aatctcttct tgagtgctac
     6421 ttcttaaaag tatcgctcag agtatcgata ttatcatttc tcattgctac actttacgga
     6481 tgtttccgtg tgtataatag aactcctccc atcatcatgc aacctatcag atagaatggc
     6541 aacattccga taccaccagt tcgaggatat tctctttttg gaggaattgg ctcatttgtg
     6601 atatagtgct tatcattcgt aaactcgtaa cccgctggta tatcttgtgg aacgattgaa
     6661 gtcacatctc tgacttctcc atttactatt tggaaggcaa cgataggctt attttgaacg
     6721 ggtttataac cagctggttc agaattttca aataatcgat atttcccatc tgacagattt
     6781 ttaaaggtca acttaccatc ttcacctgtt ctcacatttt gataagtgcc attttgatca
     6841 atagctccat aaatatctgg ataatccgga tgttgttttt gaagactaaa gaccgcatct
     6901 ctcagtggtt ttttatcatt cttattgatc ttaataaact caatttcacc aagttttttc
     6961 tcttttggaa ttgtgatttc tggatacttt cgtacatcac gaatcttagg aatcgggaag
     7021 tcgcgcactg tgttcttttc tacttcctta gggtgtaggg ttgttcgacc attcgtgtca
     7081 tagaatttat tgcttacaaa ttggtcattc aagcgaacat tataagtcaa tgtaactttt
     7141 tcacccgttc caaggtacaa acctgttaca cgaatccttt tctcagtcgt atcatagaac
     7201 acttttgcat tttttagcaa gccaccatca ttttgtggtc ccccagtagg gacattattc
     7261 accaacgaac taccatcgtt tgcagttaaa gtgtaatccg ctggatcaaa ccttccatct
     7321 gctcccaatt ggaaatcaat tagttcaccc atcgggtctg taatcgtacc attttcgata
     7381 gatttcttct cattgacgat agtatagaag tagcgattca attcttgtaa aatctgagat
     7441 ggatctgcta cgttagtgta gttgtcagga gaactagaga tgctctgcat aaatctagta
     7501 gccgttgctt catccgtacc aggatccccg tttacaccaa ccccaacagt gaagacatca
     7561 tagccatcct gagccatatt tccgttataa taccaagtcg tagggtcacc atggttggta
     7621 atccaatcgg tactagagtt aaatggatag gctagaatac tatcacgcca atataaatac
     7681 aagtcagttc catagaacct atatcccgct gaaactaatt tagctctctg ctccatggag
     7741 gtgattgaaa gtatttgatg aactccgtat tggtctgtta caggtttctt cgtaaacatc
     7801 tgataacttt caccatctcc acgaacaatc ttatgttcac catctgctga ccatgtaaca
     7861 aagtcctcca gtaatatccc gctactattt ggagtttttg ctttaaaatt attcagctga
     7921 gttctgtacg attgcgtcgt tcctgtatat ttaaaattaa ttggatatga catagtcgga
     7981 acaccatctg taatgtggaa aataaccttt ttactgtttg gtcttgcctg ctttgtcaag
     8041 atatcatcag cggtcatcaa agccttctgg gtaaaagtcg cgccgaattg atacatcaat
     8101 ttgtctttgt tcaattcctc tgcatctgat ggaatcctat ccttaatagt ttgaatatca
     8161 gtaggatctg atgtgagatt taaaaagcta taattataag ttttagctgt aaacgtcgta
     8221 cgatcgaacg tccataaagc tgagtcattc aatatttttc cgttcgcatc tgctacccct
     8281 ttttccacag tagcttctga accgtcaaag atagttgagc cataagtcac aagtgctact
     8341 cgattatctg gattggaggt aatcttatct acaagggctc gtgtcgcttc tcccgctttt
     8401 tccgctcgat gggcatgatt atgtcgaata ttactcatac tattggagtt atctaataga
     8461 ataacaacat ctagcggagt agaggcttct ttcgtttcaa ccgtcgtttt accactaacc
     8521 gtcaactcga ttccatattg gttatcatcc aaattattca cttgataaat tctctttgaa
     8581 agtgtacctt ctggaatcac acgttcatat ggattcggat tcaacgcctt gtgctgtccg
     8641 tttttttccg aaccatctac cttaataatc tgataaggtg tttgaacatc tggataagtc
     8701 cctgtttgtg gatactggtc agatagagcc tcttctcgat tttctacctg ttcaccttgg
     8761 acagtcgtcc gaccattctt ctcaacttca acagtccatt gtttagtaga gggtttataa
     8821 ccaactggag gttgggcttc tgtcaaggtg tatgtcccag gttttatgtt tgaaaatatc
     8881 gcttctcctg tttgcgcctc tgtcctttgc gaaacagttg tgccatccgt attgtttttc
     8941 aactcaaaga cggcatctcc tagaagcgct cctccttcgc ctgtctcctt aatcactact
     9001 tttcctatcg ctggactggt ttcaggcgtt tctgctaaag caactatcga agaaaaagct
     9061 gtcaactgag atatacagca cagtcctgca actgccttct gaaatatctt tcttactttt
     9121 ttcatgtgtg tctccctgtt aagcattatt catagaacaa gttaatcctt ctatgattca
     9181 taggtacttt caatctgtat acacgaagaa acggattact tatgttctga taaaatttat
     9241 ctcactgagt taatccgttc actaacaaac gtagcaaaag cgtataaaag tgcgttatag
     9301 ctatcttctc aacctggcaa tgacacactt gtatacaata tagtatagta tagtattact
     9361 attaactatc ctagtataaa ttaaaacaac ttccatcaca atagatattt ttatcacata
     9421 tttttttata gaacgacaat atttgataaa aaaatatttt ctaataaaaa aaataagcca
     9481 taaaactcca ccaatactca ttactatctt taaaatgcct tttattacat gctgttttat
     9541 caataaagtc ggaaattcca caaccttttt gacaagacaa ttagtttctt ttgtattata
     9601 ataattaaaa ttatctatat gcaactaaga ttcggtaact atgctaaaca aatacattga
     9661 aaaaagaatt acagataaaa ttaccatttt aaatatatta ttggatattc ggtctattga
     9721 actagatgaa ctgtctactt taacttcatt acaatctaaa agtctcctaa gcattttgca
     9781 ggaattacaa gaaacattcg aggaagagtt gacatttaat ttagatacgc aacaagttca
     9841 attaatcgaa caccattctc atcaaacgaa ttattacttc catcagcttt ataaccaatc
     9901 aactatttta aaaatactcc gcttctttct actacaaggt aatcaaagct ttaacgaatt
     9961 tacacaaaaa gagtatattt ccatcgcaac aggctaccgc gtacgacaaa agtgtggctt
    10021 gttactacgt tcagtaggtt tggaccttgt gaaaaatcaa gtagttggtc ctgaatatcg
    10081 cattcgtttt ttaattgcac tcctccagtt tcattttggt attgagattt atgatttgaa
    10141 tgatggaagt atggattggg tcacacatat gattgtgcag tctaattctc aactcagtca
    10201 tgaactgtta gaaatcacac ctgacgagta tgttcatttt agcatactag tggcactcac
    10261 ttggaaacgt cgggaatttc cacttgagtt ccctgagtcc aaagagtttg aaaaattaaa
    10321 aaacctcttt atgtatccga ttttgatgga acattgccaa acttacttag agccacatgc
    10381 caacatgact tttactcagg aagaactgga ttatatcttt ttggtttatt gttctgctaa
    10441 ttcttcgttt tccaaggaca aatggaatca agaaaaaaag actcatacta ttcaactgat
    10501 tcttcagcat acaagaggaa agcatctact atccaagttc aagaatatct taggaaatga
    10561 catttcgaat tctctttctt ttttaacagc actgactttc ttaacaagaa cgtttttgtt
    10621 tggtttacaa aatctagttc cctattataa ttattacgaa cattatggga ttgaaagcga
    10681 caagccactg tatcatattt cgaaagcaat tgttcaagag tggatgactg agcagaagat
    10741 tgaaggagtt atcgaccagc atcggctgta ccttttctca ctctacttga cagaaaccat
    10801 cttttcctca ctacctgcta tcccgatttt tatcatttta aataatcaag cagatgtaaa
    10861 cttaataaag tccattattt tacggaattt tactgacaaa gttgcctctg ttacaggata
    10921 caatattcta attagtcctc ctccttcaga ggagcatttg acagagccat tgattattat
    10981 tacaacgaaa gaatacctgc cttacgttaa aaagcagtat cccaaaggga aacatcactt
    11041 tttgacgatt gccttagatt tgcatgttag ccaacagcgt ctcatctatc agacaattgt
    11101 agatatccga aaagaggctt ttgacaaacg ggtcgcaatg attgctaaaa aggctcacta
    11161 tttgttataa gttcatcgta ctgtctacac acaaaaaggg gcttcctaag ccatctctat
    11221 tcttatcccc atatttccca gttttgggta aatctgaaca gaaaaacact tctgctctct
    11281 agtttctgct agtgaacaaa agtgtttttt ctggctctat aatttctgta gtgggtaaat
    11341 cccactgtgg agattatagg gctttttgag tatcaaaaaa gtcccataag acttataatg
    11401 aaaagcgcct aaacaactca ttagaaagta tcttatggaa cacatcaatc ataccacatt
    11461 actcatcgga ataaaagaca aaaacatcac cttaaataaa gccattcagc acgataccca
    11521 tatcgaagtc ttcgctacac ttgattatca cccacctaaa tgtaaacact gtaaaggaaa
    11581 acaaatcaaa tacgacttcc aaaagccttc taaaatccct tttatcgaga ttggtggttt
    11641 ccctagcctc attcatttga aaaagagacg atttcaatgc aagtcctgtc ggaaagtcac
    11701 tgtagctgaa acaactctcg ttcagaaaaa ttgccaaatc tcggaaatgg tgagacagaa
    11761 aattgcccaa ctcctactca acagagaggc tcttacacat atcgcttcta aattagccat
    11821 ctctacctct acctctacct ctaccgtcta tcgtaagctc aagcaatttc atttccaaga
    11881 ggattacacc actttgcctg aaatcctctc ctgggatgaa ttctcctacc agaaggggaa
    11941 attggctttc attgctcagg atttcaacac taagaaaatc atgaccattc ttgataacag
    12001 acgtcaaaca accatccgaa atcatttctt caagtactcg aaagaagcta gaaaaaaagt
    12061 taaagtcgtc actgttgata tgtctggaag ttatatccct ctcattaaga aattatttcc
    12121 caatgctaaa attgttctcg atcgtttcca cattgtccaa cacatgagca gggctcttaa
    12181 tcagactaga atcaacatca tgaagcaatt tgatgataaa tctctggaat acagagctct
    12241 taaatattac tggaaattta tcctaaaaga tagtcggaaa ctctctctta agcctttcta
    12301 tgctagaact ttcagagaga ccttaactcc tagggagtgt ctgaagaaaa tctttactct
    12361 agtacctgaa cttaaagatt actatgacct gtatcaacta ctcctatttc atctacaaga
    12421 gaagaatact gaccagtttt ggggcttaat tcaagacacg ttacctcatc tcaaccgcac
    12481 ctttaaaacc actttgagca catttatttg ctataaaaac tacatcacta acgccattga
    12541 attgccttat tctaacgcta aacttgaggc cactaacaaa ctcatcaaag acatcaagcg
    12601 caatgccttt ggttttcgga actttgaaaa cttcaaaaaa cggattttca tcgctctgaa
    12661 catcaaaaaa gaaaggacaa aatttgtcct ttctcgagct tagcttttct tcaacccact
    12721 acagttgaca aagagccctt tttattattc aagaacttga ttagctcaat gcatccaagg
    12781 cgtcatccat tgaaagaact tcgtggaaga cacgttgtgt caattcagtt ttttgttctg
    12841 gagtgaggta tttagtgttt acacagtatc cagagatacg tacgataacg tcttcgcctg
    12901 acatgatttt ttcgtaaaca tcgttcaagt ccataacgtt caagttaacg tgttgtccac
    12961 cgttttcgaa gtaaccatca aggattgtta ccaagttatc aacttgttca tcacgagtct
    13021 taccaagagc gcgaggtgat acttgtgtag tcaatgagat accgtcagct gcataactaa
    13081 agtcaaggct agaaagtgag ttcaagtttt gcaaccaacc acctttagct ttgttagatg
    13141 ggttagcacc tggtgagaag aattcaagtt tagacaagtt cacagaacca tcttcgttga
    13201 ggtatacacc tttgtgaact ggtgagttac cagtttgttt agagtaagca acgttagatg
    13261 tgattgtcaa aagtgatact gtagcttctg cgtctttgta tagtttgtgg ctacgtagac
    13321 gagttgtgta agcttcgatc aaccattctg ccaattcgtt tgaacgtggg tcatcttcac
    13381 cccagcgtgg gtagtcaccg attgtttcgt aatcgtagat gtagccatct tcgtcacgga
    13441 ttggtttaac tgtagcgtat ttgatagctg acaatgtatc aacagtgtta gcaaatccac
    13501 agataccgaa tcccatgttg gcacgttgtt tagttggcaa gaaggccatt tgaacagctt
    13561 cgtagttgta cctatcagtc atgtagtgga tgatgttcaa ggcatctacg taagtgtcag
    13621 tcaaccagtc aagagatttt tcaaagttcg ctttaactga ttcaaattca agaacttcgt
    13681 cacggattgg ttcgatatca aatactttgt agtctttgtg aacatcgtcg taaccaccat
    13741 tcaaaccagt aagaagggct ttaagaacgt ttacacgagc accgaagtac tggatgttgt
    13801 ggcgttgttc ttcattttct ggatcaagtg gagacacaca gcatgagata cagctcattt
    13861 caccatatcc gtctttagcc attgttgtta caccttcgta ttggatagaa gagtgtttgt
    13921 ggctcatgtg catacagtag cgacggaagt tgtatggcaa tttgtcagtc caaagaactg
    13981 tcaagtttgg ttctggtgag ttaccgatgt tgtcaagagt gttcaagaaa cggtagtcca
    14041 tcttagtaac acggtgacga ccgtcgttac ccataccagc catagaagtt gtgataaagg
    14101 ttgggtcacc tgagtacaat tggtcataag ctttggtacg agcaaattta actgtacgaa
    14161 gtttcataac gaaatcatca acgaattctt ggatttctga ttcagtaaat gtaccacgag
    14221 caaggtcacg ttctgcaaag atgtccaata cgattggtac acgacctaga gatgtagcag
    14281 caccgttaat cacacggcag acagccatga aagcaatgtt aacccattgg attgcttctt
    14341 tcacgttcat cgctggtttg cgaacatcaa ccccgtaaag gtcacccagg cgaacaactt
    14401 gttgcaatgc ttggtattga aggtttactt cttcacgaag acggattgtt tcttcatcga
    14461 tttctttgat tgcattccag tcatttactt tttcttgcat caagtagtct gcaccgtaaa
    14521 gagcaagacg tgcgtaaaca ccgatgatac gtccgcgtga gtatgcatct ggaagaccag
    14581 ttacagtgtg tgcgtgacga gcgcgacgaa tatttgaagt gtaggcacgg aaaataccgt
    14641 cgttaactgt tgttacatat ttagtgaaga tttcgtgaac agctgggtct ggttcgtatc
    14701 cattttcttt caaagtagtt tcagccatac ggataccacc ttttggcatg aagttcaatt
    14761 tgaagagttc atcgttttgg ataccgaaga taacttcatt ttctttgtcg ataaatccag
    14821 cagggatatc agcgatagat gttggacgag tgtccattgg gaaacgagtt tcttcgtagt
    14881 gtgctttagt ttcttctaca attttcttga tgtgaagtga acgctctgtt ggtcctgcaa
    14941 ggaagctttc gtctccatca taaggtgtgt agttagcttg tacaaagcgt gatacacttg
    15001 ctttttcttt ccaatctacg cctttgaagc cttcccaagc tttgtcaaaa atatcttgtg
    15061 cttcaacaac tgtcttaaca accatattaa tgtcctcttt tttctagtaa cagtcatctg
    15121 ttacattcat gagacaagta taccatatag taaccgattt caacaagtga aaaatcccta
    15181 tttttaaact ttcttttcta aaacagtcta tattttattt caaactgtat tatatttttg
    15241 aaaaaataaa gtcctttttt ctttttttca gaaaaaaggg tataataaaa gaaaataagc
    15301 agtaacactc aatggaaatc gaaaagcaaa ctaggaagct agccgcaggc tgctcaaagc
    15361 actgctttga ggttgtaaat agaactgacg aagtcagctc aaaacactgt tttgaggttg
    15421 cagatagagc tgacggggtt tgaagagatt ttcgaagagt ataaaaaggt gctaggcatg
    15481 ttgatttttc ctttgttaaa tgatttgtca agaaaaatca tccatattga catggatgcc
    15541 ttttttgctg cagtggaaat cagggataat cctaaactca gaggaaaacc tgtcattatt
    15601 ggaagcgacc ctcggcaaac aggtggacgg ggagtcgttt ctacctgtag ttatgaggca
    15661 agagcttttg gtgtccattc tgccatgagt tccaaggaag cttatgaacg ttgtccccaa
    15721 gccgtcttta tctcaggaaa ttatgagaaa tacaaagctg tgggactcca gattcgagct
    15781 atttttaagc gctatacaga tttgattgaa cccatgagca ttgacgaagc ctatttggat
    15841 gtgacagaaa ataaacttgg tatcaagtca gcggtcaaaa ttgctcgcct cattcaaaaa
    15901 gatatctggc aagaactcca tctaactgct tctgccggta tttcctacaa caagttctta
    15961 gctaaaatgg cgagtgatta tcaaaaacct catggtttga cagtgattct acctgaacag
    16021 gctgaggatt ttctcaaaca aatggatatt tccaaatttc atggagtagg aaaaaagaca
    16081 gtagaacgtc ttcatcaaat gggcgttttt actggtgctg atttacttga agttcctgag
    16141 gtgaccctaa tagaccgttt tggtagacta ggctatgatc tatatcgaaa ggctcgtggc
    16201 attcacaact ctccagtcaa atccaatcgc atccgtaaat caatcggcaa ggagaaaacc
    16261 tacgggaaga ttctccgtgc cgaggaagat atcaaaaaag agctgactct tctatcagaa
    16321 aaagtcgctc tcaatctaca tcaacaagaa aaagctggaa aaattgtcat tttgaaaatc
    16381 cgctacgagg acttttcaac tcttaccaaa cgaaaaagtc ttgctcaaaa aacacaagat
    16441 gctagtcaga taagccaaat agccctgcaa ctctatgaag aattaagcga gaaagaaaga
    16501 ggtgtccgcc tattggggat taccatgact ggattttaaa gctcaatgaa aatcaaagag
    16561 caaactagga ggctagccgc aggctgctca aaacactgtt ttgaggttgc agataaagct
    16621 gacgcggttt gaagagattt tctaagagta taaaaccttg aagagttgcc ccttcaaggt
    16681 ttttcttata caaataaacg gacaaaactg taaagtagca aaacactacc aagcacgata
    16741 cggtatttac caaaaagggt gaagtcgtgt tttttcacat agctggtcaa gaagcgaata
    16801 gccaccatgc tgaccgcaaa agctactccc atcgcgacca agagcaaaaa caattgccca
    16861 aagctcaaga gttctccggc tttcacaaat ttgaaaatct ttaaggcact agctccaaac
    16921 ataacgggaa tcccaagata gaaggtaaat tctgtcacaa ctgaacgact ggttccattt
    16981 aacaaaccac cgacaatcgt tgcacctgaa cggctagtcc ctggtaaaag agcaagaact
    17041 tggaagagtc cgatatagaa agcggtcgta taaggaagct tgtccaactc tgttacactt
    17101 ggctcgatag cacgcgcttt attgcgcttt tccaaataga tgaaggcaac cccgtagata
    17161 atcaacatga gagcaactga aaccatgtta tggaagtggg tatcaaacca atcatcaaat
    17221 ttaaagacac caagtaaagg caaagtggca atcaagacct tcaaccatag tctccaagtc
    17281 ttacgaactt cctgtttgtc cttagtcggt ttaaaaggat tgagcttgtt aaaataaatc
    17341 accataactg ctaaaatagc accaagctga atcacgacat taaacatgga cataaaggct
    17401 tcattttgat tttggtattg gataaactcc tctgctaaaa tcaagtgacc tgtactggaa
    17461 atcggcaacc attccgtaat tccttcaaca atcccgaaga agatagattt taaaatttca
    17521 ataagataca tatatttctc cttatattat atttaacgca gttagctact gccaaagccc
    17581 aagtggtata cttggaataa gccactgtgg attagttcat ttcctccaat cgcttgacga
    17641 tttccgaaag ggtctaacca cagctttttg tttcaattgg taatgagttt gataacgcat
    17701 agacgtttta tctcgtctaa ggtaacaagg caaaaagttc gtggataacc aagtagactt
    17761 gaaatactat atctggaggt actcccatgc tttatgtggg cattgatgtc gctaaaaata
    17821 aacacgatgt tacagccttg aatgttcgag gaaaactgtt cttaaaccac tcactttttc
    17881 aaataataaa gctggttttg aacttttaga tctgtctctt cgacagctca accaagacta
    17941 tctcatcgct cttgaagata ccggacatta tgcctttaat ctactgaact tcctgcatga
    18001 acaaggatat aaagtttaca cctacaatcc tttgctcatc aagaaatttg ccaaatcatt
    18061 attacttcgc aagactaaaa cggataagaa agacgctcat ggcatcgctc ttaaacttct
    18121 ttctgacccc aatcgtgaac aatttcaaca cgataatcgg caagtagaac taaaaatact
    18181 ggctagacat attcatcgtc tcaagaaaaa acagtctgat tggaaagtgc aatacactcg
    18241 ttgtcttgat atcatctttc ctgagttgga taaaatcgtt ggaaagcatt cagaatatac
    18301 ctaccaactc ttgacatgct accctaatcc tcagaaaagg cttgaggcag gatttgataa
    18361 tctgatagaa attaagcgat tgaccgcttc taaaattcag gatatcctct cagtcgcacc
    18421 tcgttctatc ggaacaacat ctcctgctcg tgaattcgaa atcatcgaaa acatcaaaca
    18481 ttacaagagg ctcattgaca aggcggaaaa atgtgtcaat gacttgatgg ctgagttaaa
    18541 ctcggtcatc acgacggtta ctgggattgg gaatcgttta ggggcggtca ttttagccga
    18601 gattcaaaat attcatgcct ttgataatcc tgctcaatta caagctttcg ctggactgga
    18661 ttcttctatt tatcagtcag gtcagattga tttagctgga agaatgatca aacggggttc
    18721 ccctcatctg cggtaggcac tcatacaagc tgccaaagca tgcgctcgct tttcacctgc
    18781 ttttaaggcc tatcttaaga ctaagttaga ataaggaaaa cattacaatg tagccatcat
    18841 ccacct
//
LOCUS       DAVDHC010000040        18683 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVDHC010000040 DAVDHC010000000
VERSION     DAVDHC010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18683
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.040"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(131..355)
                     /locus_tag="VUR43_001903"
     CDS             complement(131..355)
                     /locus_tag="VUR43_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET5413545.1"
                     /translation="MIEILIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFILLLTFMVITYK"
     gene            complement(360..539)
                     /gene="asp4"
                     /locus_tag="VUR43_001904"
     CDS             complement(360..539)
                     /gene="asp4"
                     /locus_tag="VUR43_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET5413546.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            complement(541..1878)
                     /gene="gtfB"
                     /locus_tag="VUR43_001905"
     CDS             complement(541..1878)
                     /gene="gtfB"
                     /locus_tag="VUR43_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET5413547.1"
                     /translation="MIELYDSYSQESRDLHESLGATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYADGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFATTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIAGALPDVTFRIAAVTEMSSKLLDMLCYPNVALY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPDH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQETMQTVLGG"
     gene            complement(1871..3382)
                     /gene="gtfA"
                     /locus_tag="VUR43_001906"
     CDS             complement(1871..3382)
                     /gene="gtfA"
                     /locus_tag="VUR43_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET5413548.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            complement(3394..5769)
                     /gene="secA2"
                     /locus_tag="VUR43_001907"
     CDS             complement(3394..5769)
                     /gene="secA2"
                     /locus_tag="VUR43_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET5413549.1"
                     /translation="MWNKNRQLRKVKKILNQINRRKEEMALLTDEELAAKTQEFKRRL
                     TAGETLDDILVEAFAVVREADKRILGMFPYDVQVMGGIVIHQGNVAEMNTGEGKTLTA
                     TLPIYLNALSGQGVILVTTNSYLAKRDAEEMGKVYEFLGLTIRLPFADDEEEKITPKE
                     KKEIYSADIVYTTNSGLGFDYLIDNLASSEEQKYMPEFNFVLVDEIDSVLLDSAQTPL
                     VISGSPRVQSNFYGIIDTLMTTLVDGEDYIFKEEKKEVWLTNKGAKIAEKFLGIDNLY
                     AEENNVLARHLVFALRAHTLFKRDKDYIIRKGEKDQELVLLDQGTGRLMEMTKLQGGL
                     HQAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVR
                     IPTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLL
                     FREGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIV
                     IGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQD
                     MTQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDG
                     SRDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVR
                     SFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQS
                     ASQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            complement(5759..6238)
                     /gene="asp3"
                     /locus_tag="VUR43_001908"
     CDS             complement(5759..6238)
                     /gene="asp3"
                     /locus_tag="VUR43_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET5413550.1"
                     /translation="MVIRRQKEIFWGEFKGASLGNLRENSFLYGSIVIYYARNHIYFE
                     NEMISSGTMVHEWTSSFNFQGNRLTPTLPLIKKGHRYRLTSNMTIKPDNGLYFRLIFK
                     DRYDEKVSQLIKKDLTFTFTYPEEAYNYSIQLLSAGLKSVDFHSFSIEEDYTEQNVE"
     gene            complement(6238..7770)
                     /gene="asp2"
                     /locus_tag="VUR43_001909"
     CDS             complement(6238..7770)
                     /gene="asp2"
                     /locus_tag="VUR43_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET5413551.1"
                     /translation="MSNKLHILQIGNRNWSHYYEIPENIEWHFFWPGSTTAIKKVMKM
                     EGIRTFSGVVIENPDYLPDLLPLINILTPYTIFYSDICASYSPLVEEFLKKTCAQVTD
                     FSNPRELLRILSKALFKGQYGDKLTPIDMVVNPYFAGSIRYNGYENLELVGSYGEDFR
                     PLISWKYNIRASEWNPIELWLEYEKDLSCDIRIVVRNIQDGSTADFIKERIFTTDDME
                     AAILLDDDFSSFISVSLEAKGNGRLKIGALHQRLTRYQFGKFVLGGNIIRSKNREEIN
                     YFFYPGDFKPPLNVYFSGYRRAEGFEGFGMMKSLGSPFLLFQDPRIDGGAFYLGDDDF
                     ENAVRRVIQHHLDLLGFSNKELILSGISMGTYGALYYSSDFEPKAVIVSKPLTNLGLI
                     AERGRLEAPGLFPTAFDILRHHSQGKADIDSINILNARFWERFRGADFNQTIFGLSYM
                     KEEDYDPIAYDSLVDSLYSTGARIMVKGTSGRHNDDNDSTILWFVNFYKMVLEQEFGR
                     KY"
     gene            complement(7760..9334)
                     /gene="asp1"
                     /locus_tag="VUR43_001910"
     CDS             complement(7760..9334)
                     /gene="asp1"
                     /locus_tag="VUR43_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET5413552.1"
                     /translation="MYYFIPFLESMNQSWQVDIVPWYQTTHRLEFDDVLHQIRIFKRE
                     GIKSKIVLLPYHPHMRYLLHRQDLLEVEAFSVFDAIQDIENEEIYPLQLKDLAWDEDC
                     DFIYTPFLIAVKQKGELHAHIEFGTEGFISYITYFKDNQVDFICYFDDRGFLSSLVKY
                     QDNQAVSRYYYNSNAEWQIKEYLQGIHTKVEVNPRFSHRFRKSTYQSVDEVVWEFFEK
                     FLTAEYKEGESFVLAAQTKYQNQLLKHLPEHADKILTFFIERNQEDDLNLHHQAVKQA
                     KILISDRQDFLERLKQHYPQFTYKMHHLPSFDTRLKLGVSQRVKESKLYVQLDLNTPL
                     NSEALYEVLNFVSQNPLTEIVFATFNAEGYQIEALQKHLFTLISERLNFRDLLKESII
                     SGAENKLEENKEENYRFQIVNLNDEIGLIRELEYTRLIVDLNPIANIYTQIAGISAGI
                     PQINLSESEYVTHLQNGYILSDLSEFSKAGHYFLDTLEHWNQALIHSIDKIRQNTGNQ
                     FVQKWERWLEEAKSEQ"
     gene            complement(9623..10849)
                     /gene="secY2"
                     /locus_tag="VUR43_001911"
     CDS             complement(9623..10849)
                     /gene="secY2"
                     /locus_tag="VUR43_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET5413553.1"
                     /translation="MKKKLKSVVVKRVMWTICFIFVYILGSRLTLPFVNVNDTSFLGG
                     NAAFLAFSTAMTGGNLRSLSLFSVGLSPWMSAMILWQMFSMSKKLGLGNLPLEIQERR
                     KMILTFIISFIQTLAITLNLPIQEGVNHDLVLILNILLLISGTFFLVWLSDLNSLLGV
                     GGSVVILMSSMIVSVPENIVRSIIDLHVNLLFIISLLLISIAFLYIAVRVQKARYRIL
                     VNKIMIHNRFKRYSYFDIMLNPAGGMPFMYAISLVSIPQYLLMLLHIFVPKTRWVDNW
                     IAEFTIGRPVWVYTYIIVLFLLGIAFAFVNMNGEQIADKMKKSGEYIYDIYPGEDTAL
                     YINRLVLRFAVIGSIYILLMAGIPMLIILYEPRYMQLSMLPGLFLMFNGMIFNVKEEI
                     NALTLNESYRPLVERK"
     gene            complement(10937..11944)
                     /locus_tag="VUR43_001912"
     CDS             complement(10937..11944)
                     /locus_tag="VUR43_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET5413554.1"
                     /translation="MKINITNIYGMSGQSTALIAQNETVKIAKKLDFHELSFYFYNIY
                     SDSEGELTSRLDGVLAKLGYGDIVVYQSPTWNGREYDQAFIRKCKILNTKIITFIHDV
                     PPLMFPSNYYLMSEYIEMYNQSDLVVVPSEKMKERLIQEGLTVQKIIIQGMWDHVHNY
                     PLKQPSFQKKLYFAGSVERFEHLSNWSYSTPLDIFSESNYENSNPRVSFKGWKTDPEL
                     LFALSEGGFGLVWGTNENPTDEEDYYRLNISHKVSTYLAAGIPVVVPSYLSNASFIKE
                     KGLGYVVDSLEEANRLVEETTVEVYQQMVENVSKVSYALKEGYFTKKLLTDAIMQLLD
                     I"
     gene            complement(11953..15171)
                     /locus_tag="VUR43_001913"
     CDS             complement(11953..15171)
                     /locus_tag="VUR43_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET5413555.1"
                     /translation="MKAIVLAGDKNYLTPILTTIKSILYYNQNVKIYILHQDIPSDWL
                     QELKIQVEKLGSVVEDIYIGDAIDAEWKTQEHISPIAYARYLISRLITEDRVVYLDSD
                     IIVNGDLSPLFELSLGDYSLAAVRDVDGNGFNSGMLVIDCQKWREKDVTSMLFDKTVE
                     YMSYLDHTDTDGFNGDQTIFNLVFQNHWLELDKRFNFQVGHDIIAFYSHWDSHFELDE
                     EPLIIHYTTYRKPWTTLMGYRYRDLWWSFHDVTFDQISDHYQGRFAVKRVYYFHDINL
                     FTFTDSQDLLYIDELAQSLLDIAFHIGAYTDMGDILLALDKYPNVYLYPSMVGAVIDE
                     MIEKSDAYLDIHKGSSMDFIVNRYTSAGRPVLTFDVTNKNQLEEIVVPSQSPLEMIKV
                     IKKLKSDKMETKAIVFGANYQYADKVLTTIKSICCHNRGLRFYLINSDFPTEWFYNLN
                     RKLTKLDCEIVNARVNSSHISQYKTNIHYAVFLRYFISDFVEEAKVLYLDCDLVVTRD
                     LSPLFDLELGDYPLAAVKDLGGQIYFGEHIFNSGVMLINNRLWKQEEVRKQLIEMTNE
                     LHDKVAQSDQSILNLLFKDRWLALDFKYNCITLHTHFSDYRPESGTYPPIIHYLTERK
                     PWGLYECSIYRDVWWYYNAQDWSDMSQVTPSLTKDQVSQYTGVQYSALVYTFSSDLRN
                     MGYLIENLPDVKFYVAAPVMVADSITDLLAYPNVSVLSDIAGQPPLIDSLVEGCDFLL
                     DINADIEVDGIIERFRQAGKPVFAFESVVHGEQGQFLYDQAHPEEMVLAIEAYCQNGE
                     LPVKKFQSYPKVLDIQQSLDYILEHHSSVIRYGDGEMDIMMGHGIPYQDYDETLAEQL
                     RSMIQLESSPELLVCLSDVFEGLERYNSESVNFWKKHLEHYKDAYQQYCTASFYGSTF
                     ISRPYMDLKDKTTSVAHFEKLKQLWDERDILIVEGENSRSGVGNDLFDNAQSVERIIC
                     PSRNAYGKVQVIQETVEKYADGKLVFLMLGPTAKVLAYHLSQKGIQAIDLGHVDSEYE
                     WFKIGATSKVKFSHKHTAEHNFDQEIQFVEDEIYNKQVVVRI"
     gene            complement(15310..16518)
                     /locus_tag="VUR43_001914"
     CDS             complement(15310..16518)
                     /locus_tag="VUR43_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET5413556.1"
                     /translation="MTDKASKKAIVLGADSNYMDKVETTIKSVCSHNRDIRFYIFNSD
                     FPTEWFQLMNKRLSVLNSEIINIKITDDTISHFHLPTPHLSSATYLRYFIPNFVFEKK
                     VLYLDSDIVVTSSLTALFDIDLDGYPLGVVPDIPTTDEEFNSGVLLIDTNRWREEDIY
                     RQLFELTIAHHEHVYGDQGIFNILFKDRWKRLDITYNLQVGVDAHRYYMGDYDWYELF
                     EGVPCIIHYTTENKPWKHFRFNRFRDVWWFYYGLNWNDILLRTHVLKETFLELISPIS
                     KHVSIFTNTGDIESIGYLLEKLPDVQFHIVAPTYFSPNVIELQRYSNCYIYPCADPKM
                     KQDIIDKTDICLDINYGPAMDQMLQEMVRRGKTIYSFDCTNHFFNGESTVFTVDEIDE
                     LIRSVKELKM"
     gene            complement(16551..17429)
                     /locus_tag="VUR43_001915"
     CDS             complement(16551..17429)
                     /locus_tag="VUR43_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5413557.1"
                     /translation="MKDLVSVVIPVYNVENYLEECIQSVLNQTYTNLDIVLVNDGSTD
                     ASAEICDRFAEIDDRARVFHTENRGAALAKNFGVTQALGEYVLFVDSDDIAEKRMVET
                     LYRQVEETGADIVIGNYFLYDENDGQYKLYVLERDFCIEELSAQELIDRQAGKWHLNA
                     SAFIMPVFKLFKKDLLLQVPFTNGRRFDDEATIHRLFIKSQKTIFVNDNLYIYRVRKG
                     SIMTSQFDLSWVQDILQVFSSKLADLLLAGIDTSIMRTRFINILNEYKYLCENYNFTD
                     TDEYREILFRLDLFKE"
     gene            complement(18144..>18683)
                     /locus_tag="VUR43_001916"
     CDS             complement(18144..>18683)
                     /locus_tag="VUR43_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5413558.1"
                     /translation="SASTSASTSTSASESASTSASASASTSASESASTSASASASTSA
                     SASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASTSASTSASA
                     STSASETMSTSTSVSTSESTSTSGSTNSRPQETITNSRQELPNTGEKQSVKSGLLGLI
                     LGLTGLGLVAKRRKRDDED"
BASE COUNT         6052 a         3913 c         2844 g         5874 t
ORIGIN      
        1 tatctacaac ctcaaaacgg tgttttgagc agcctgcggc tagcttccta gtttgctctt
       61 tgattttcat tgagtataaa aaagaaaact tcagaccaat ccacaaaagg tgaatatctg
      121 aagttttctt ttatttataa gtaatcacca taaaggttaa tagtagaata aataaagcca
      181 aactcaccaa taaagtgagc accttgacca aggtgttgct ctgccagtag cttggtttac
      241 caatattact agtggcatcc atggaaaata gttgattttg acggggttgt atagttacca
      301 atacaatcaa agcaagagat aggataatag ctaaaacaat tagtatttca atcatagatc
      361 tacctcaaaa ttcccagcaa agtaaagagc aaaccaatca gaatcatcaa acccagtaaa
      421 agtgaaaaag tcttactaat cttttcccct cgggtttctt tttccttctt gatgggtttt
      481 tgtttcaact cttccatgcg gccttcaacg tctttgtaaa ataaatcttc ctctgacatg
      541 ttagcctcct aaaacagttt gcatggtttc ctgatatctc accaagtcaa cataatttgc
      601 atgttggcct tgtttgccaa gtgcctgacg catttgatca acatctgaaa gggccaattt
      661 aatggtctca accaaagcag caacttcact actttcaaat agatggtctg gagcgatata
      721 aagtctattg tgcaccgtct gattaaagcc aagaatcaag agattgtgct caaaggcctg
      781 acgcactgcc tgtagcaact cattactgtg gtttatatcc aagtaaatat ccgacagttg
      841 atacagctcc tgaatcttct gtggactagc gttctggtaa agggccacat taggatagca
      901 aagcatgtct aagagcttag aagacatctc tgtcaccgct gcaatacgga aagtgacatc
      961 aggcaaggct cctgcgattg cttctacttg ctcaatctga tctgaattgg tcaagattaa
     1021 ggcatctcgt cttaggaaat tatcacgttt gaactggtaa tgataaccca agtgcacaaa
     1081 ctgatcatgg tatttctcgt cagttaactc taaagcgcgc tcataagtcg ccttatttgg
     1141 aatgatgatc ttcttagtac gcacattatc actttccaaa atcaactgca tattacctgg
     1201 aatggcatca tagagaggtt cctgccatac caagacatcc gagccagatt tatctggatg
     1261 atggaaggaa accaagaaag gagtcgctag agtattaaag ataagctgac tggtatctat
     1321 ttccaaatct tgcaaaaaga aggtgataaa ttcaacttta tttgcaaagt aacgcatgga
     1381 ctgacctggc aaagtcaata agatatcacc cgtcacatgg ttttccagta aaacttgttg
     1441 accattgaca tcttggtaaa ctgtcataat cggctcgcta tctgcgctat aagtcgttgt
     1501 agcaaaacaa gctccgaagc gattgtagtg gtcaacctga cgtactcgac cttctaggtc
     1561 tttccagtct acctgtttaa ccaagcgagc ctgcattcca tcagcataat gaatgacagc
     1621 cctctcctgc gtcacatctt caatacaagc agactgatta tctcctaaaa tttcccaaaa
     1681 atctgaaacg ggaacttgat taaaatagag aggttttcca tcctcgtaac ctagataata
     1741 ggtaaaagga gaaagcagac catcaggcag aaaaccatct gcatcgatga ccactccaag
     1801 ttgagaaaga ccagtagcgc ctagactttc atgtaaatct cgactttctt gactgtaact
     1861 atcataaagt tcaatcatgg agcacctcct ctactgtttt cttccacttt tctaaaattt
     1921 ctttggtcaa gaagccttct gcaatttggt aagaataggc acgcatagct tccaaacgat
     1981 tttcttgata caattgacaa atcttagcgg cataagcttg cttgatttgg tcttctacat
     2041 gatcagatga acttggaatc aaataaccat tttgcccatc ctctataaag gtctgattac
     2101 cataaggcac atcaaaacca attagaggta gacctgaacc aatagcttcc atcaaggtca
     2161 gaccaaatcc ttcgctggta gaagccgtta agtagacctc atactggcta taaatctgcg
     2221 aaagttccgc atgccccttg agttggatat agtcctctgc ctgatgattt gcaataattt
     2281 ctctaagcag agaatcttct ccaccactac catagatatc aaaggttagt tccggtaact
     2341 ccttatgagc ttcaatcaca gctttcacaa gccaatcaat gtgcttttct ttggcaagac
     2401 gtgaagccgt aatcaatgaa aatggtttgc gcccttgact tgaatctgtc aaggaatcaa
     2461 tactgcctac aggaatggta acaatctttg gctgatgctg agtatatttg gcaaattgct
     2521 cttgtagaac ttcattttgt ctatcagtag acacgataaa gaagtcaacc ttatctgcat
     2581 tggtaaactg atagtcataa tagttattcc aaaggatgta gtcctcattt gtagcatttt
     2641 cactataatg ctccgcatga acaactaccg ctaaatgtgc tgtctgtgct tcctcaaaca
     2701 caacctgacc aatgcctgtc tccctatcga gaatgaccaa atcagactta ttcaaattca
     2761 aagatttcat aaaggcacgc acaaaagctt gctttccata gaaaatctta tccttgaaat
     2821 gataaacttc ttccttccct tgattcatca aaatatcata gactggagtc ccgtcttcat
     2881 tgtaaaaagt tcgttggtat aagactgcaa cattgtcctt gggagcaaaa tactcgctac
     2941 aataacgcgt ataagaaaag taatccttcc gaatcaggtt tcccttaaaa acatactcgg
     3001 catgttgaac caagtccttg ttctcatcaa ctaaataaca ggttacaaac ttatcttggt
     3061 caaaaaagaa gacacgtaaa accttgccat ttttttctct gtgactttct tcaccaccaa
     3121 agtaagccaa gacatcatcc actgtcacgc tagtaggcgc aattttgata tctgtgaaat
     3181 gattataaag ccagataacc tgattatcat caaaaccaat attggctgtt aagtgctgaa
     3241 tattatcggc taaaatcata tctgtaaaga taaacttaga ggacagattt aatttccgaa
     3301 aaacaccagc acgataggct tgagcgtatt caacaccgct actagcccaa ccaattccta
     3361 aatttatatt gtaaattgtc atattttctc ctcttatgga aaatgagtca cgatttcacc
     3421 ttttggagtg acctcaacca gccccatcag gagattacgc accatatccg cacggatttg
     3481 ttctttcata gcttcaaagc ccgcgtaggc ttcttgatag tactctacga ttggattttt
     3541 ctgactagca gattgaccac cgatagccat ggatagctgt tgtagatagt ctacctgctc
     3601 tacccagttg tcatcaatgg ctttaagcag tgaaagtcgt aaaaactgtt catataagtc
     3661 atgttgatta agtaattctt tcttttcaga aagttcttta tcaatcacct gcttcataaa
     3721 gctacgaact gcagttttgt cagttacatc tatataatct ggaacctctt taacatgaaa
     3781 actaatattg gtcacaataa agtgaaacaa taattcacga ctagcatagt gatcagccgc
     3841 tacctcttct gtatatctct caatgatatc cacaacaaca tcctctaagt cacgagaacc
     3901 atctattaga cgatttctct ctttatagac tatatcccgt tgtatattca tactttcagc
     3961 atactccaga gtctgacgac gtgctgaacg tccagcacta tcactggcat gctgagcctt
     4021 ttcgactagt ttccggtatt tacgaccttt caatacttcc ggttgagtca tatcttgaac
     4081 ctgatagtct ttgtactttt tatgcaccca agatggacca aacttcttga taacatcatc
     4141 ctctaaggat acaaaaaatt tactcatacc aggatctccc tgacgaccag aacggccacg
     4201 aatttgtagg tcgatccgct gactttccat tcgctcagtc ccaataacaa tcaagccccc
     4261 aagctctgca actcctttac caagcttgat atccgtacca cgtcctgcca tagaggtagc
     4321 cactgtcaca gcccccatct gacctgactc ggagataatc tgagcctcac gcgccgcatt
     4381 attagcattt aggacattat gggcaatccc ttcacgaaac aagagagacg aatagagttg
     4441 agacatttca actgagccta caaaaacgag taagggattt cccttagcat ggtattgctt
     4501 gatgtactcc aaggatgcat acactttttc aggtaaagtg atatatagat tatctggata
     4561 gtcaatccgt tgtctcggac gattggttgg aatgcgtact acagacatat tataagtttc
     4621 aataaactct ttttccgcga ccttacctgt ccctgtcata ccagatatct tattaaacat
     4681 cttaaaaaga ctctgatagg tgatcgaggc catagcccgc gtctcaggag ataatttgac
     4741 atgttccttg gcttcaatag cctgatggag acctccttga agtttagtca tttccattag
     4801 acgccctgtt ccttgatcca acagaactag ttcctggtcc ttttcccctt tacggataat
     4861 ataatcctta tcccttttaa atagagtatg agctcgcaaa gcaaagacca aatgtctagc
     4921 caatacatta ttttcttcag cataaagatt gtcaattcca agaaattttt ctgcaatctt
     4981 ggcaccttta ttagttagcc agacttcctt tttttcttcc ttaaatatat aatcttcccc
     5041 atctactaga gttgtcatca aagtatcaat aattccataa aaattagatt ggactcgagg
     5101 tgagcccgaa atgacaagtg gagtctgagc actgtctagc aacaccgaat caatctcatc
     5161 aactaaaaca aaattaaatt caggcatgta cttttgttct tcacttgacg ctagattatc
     5221 aatcaggtaa tcaaaaccta atccactatt ggttgtatac acaatatctg cactatatat
     5281 ttcttttttc tctttaggtg taattttttc ttcctcatca tcagcaaagg gtaatcgaat
     5341 agttaatcct aaaaattcat aaacctttcc catttcctct gcatcacgtt tagcaagata
     5401 agaattagtt gtcacaagaa tcacaccttg tcctgataaa gcattgagat aaataggtaa
     5461 ggtagcagtc aatgttttcc cttcaccagt attcatctca gctacatttc cttgatgaat
     5521 tacaattcca cccatgactt gaacatcata aggaaacatc cctagaattc gtttgtcagc
     5581 ctctcggaca acagcgaaag cctcaaccaa aatatcatct agggtttctc ccgcagtcag
     5641 ccttctttta aattcttgcg tcttagctgc taattcttca tctgtcagta gggccatctc
     5701 ctcttttcta cgattaattt gattcaatat cttttttact ttgcgtaatt gtctattctt
     5761 attccacatt ttgttcagta taatcctctt ctattgaaaa tgaatgaaaa tcaactgatt
     5821 ttaaacctgc acttaacaac tgtatgctat agttataagc ttcttctgga taagtaaaag
     5881 taaaagttaa atctttctta atcagttggc ttaccttctc gtcatatcga tctttaaaaa
     5941 taagtctaaa atataaacca ttatcaggtt taatcgtcat attacttgtt aaacgataac
     6001 gatgaccttt ttttatcaga ggtaaggtgg gagttaaacg attcccttga aaattgaaac
     6061 tagaagtcca ttcatgtacc attgtccctg aactaatcat ttcattttca aaataaatgt
     6121 gattacgagc gtaataaata acaatcgaac catagagaaa gctattttct cttaaattac
     6181 ctaaactagc tcccttaaat tctccccaaa aaatttcttt ctgccgtctt atgaccatca
     6241 atactttctc ccaaactctt gctccaaaac cattttataa aaatttacaa accataaaat
     6301 agttgaatcg ttatcatcgt tatggcgacc agaagtacct tttaccataa ttcgagcacc
     6361 tgtactataa agcgagtcaa ctaaactatc atatgcaatc ggatcgtaat cttcctcttt
     6421 catatatgat aatccaaaaa ttgtttgatt aaaatctgcc cctctaaatc gttcccaaaa
     6481 acgagcattt aaaatattta tagaatctat atcagccttt ccttgggaat ggtgacgtaa
     6541 aatatcaaaa gcagttggaa ataatcccgg tgcctcaagt cgtcctcttt cagcaatcaa
     6601 gcccaaattc gtcaaaggtt ttgacacaat tacagccttc ggttcaaagt ccgaactgta
     6661 atataaagca ccataagttc ccatagatat tcccgataaa attaactctt tattggaaaa
     6721 tcctaacaaa tctaaatgat gttgaatcac tctgcgaaca gcattttcaa aatcatcatc
     6781 acccaaatag aaggccccac catcaattcg cggatcttgg aaaagaagaa aaggagaacc
     6841 caatgatttc atcattccaa acccctcaaa tccttctgct cgacgatatc cagaaaaata
     6901 tacatttagt ggaggtttaa aatcacccgg ataaaagaag tagttaattt cttctctatt
     6961 tttactgcgt ataatattcc cacccagcac aaatttacca aactgatacc gtgttaaacg
     7021 ctgatgaagc gctcctatct tcaatctccc gtttccctta gcttccaatg atacactgat
     7081 aaaagatgaa aaatcatcat ctagcagtat agctgcttcc atatcatctg ttgtaaaaat
     7141 tcgttctttg ataaaatcag ctgtagaacc atcttgaata tttctaacaa caattcgaat
     7201 atcacaagat aagtctttct catattccaa ccacaattca attggattcc attcacttgc
     7261 tcgaatattg tacttccaac taattagtgg tctaaaatcc tcaccatagc tcccaacgag
     7321 ttctaaattt tcatatccgt tgtaacgaat actacctgca aaatatggat tcacaaccat
     7381 atctatcgga gtcaacttat ctccatactg acctttaaat aaagccttag ataaaatccg
     7441 taataattct cttggattgg aaaaatcagt gacctgtgcg catgttttct tcaaaaactc
     7501 ctcaaccaat ggagaatacg atgcacagat atctgaatag aatatagtat aaggagtcaa
     7561 gatgtttatt aaaggaagta aatctggtaa ataatctgga ttttcaatca ctactcctga
     7621 gaatgttcgt atcccttcca ttttcataac tttctttatg gcagttgtcg aaccaggcca
     7681 aaaaaaatgc cactctatat tttcaggtat ctcataataa tgactccaat tccgattccc
     7741 tatttgcaat atatgtaatt tattgctcac ttttcgcctc ctctagccat ctttcccact
     7801 tctgaacaaa ctgattccct gtattttgtc gaatcttatc aatagaatgg attagagctt
     7861 gattccaatg ttccagagta tctaagaaat agtgcccagc tttactaaat tctgataaat
     7921 ctgataaaat atacccattt tgtaaatgag tcacatattc cgactcggat agattgattt
     7981 gaggtattcc tgcactaatc cctgcaatct gagtatagat atttgcaata ggatttaaat
     8041 caacaattaa acgagtatac tctaactcac gaatcaaacc tatctcatca tttaaattta
     8101 caatttgaaa acgataattc tcttccttat tttcttctaa tttattttct gctcctgaga
     8161 taatcgattc ttttagcaaa tctctaaagt ttaaacgttc agaaatcaaa gtaaatagat
     8221 gcttctgtaa tgcctcaatt tgataaccct ctgcattaaa tgttgcaaag acaatttcag
     8281 tcaatggatt ttgagaaaca aagtttaaga cttcatataa tgcttctgaa ttaagaggag
     8341 tatttaaatc tagttggaca tataattttg actcttttac tctctgactg actcctaatt
     8401 ttaaacgtgt atcaaaagat ggtaaatggt gcattttata ggtaaattga ggatagtgct
     8461 gttttaatct ttctaaaaaa tcttggcgat cactgattag aatcttagct tgttttactg
     8521 cttgatgatg aagattcaaa tcatcttctt gatttcgctc aataaaaaaa gtcaaaattt
     8581 tatcagcatg ctctggtaag tgttttaata attgattctg atacttagtt tgagctgcaa
     8641 gaacaaatga ttctccctct ttgtactctg ctgttaaaaa tttttcaaaa aattcccaaa
     8701 caacttcatc cacgctttga taagttgatt tccgaaagcg atgactgaaa cgggggttaa
     8761 cctccacttt cgtatgaatc ccttgcaaat attccttaat ctgccattca gcatttgaat
     8821 tgtaataata acgacttact gcctgattat cttgatattt cacaagacta gataaaaagc
     8881 ctcgatcatc aaaataacaa ataaaatcga cctgattatc tttaaaatag gttatataac
     8941 tgataaaacc ttccgttcca aattctatat gtgcatgcaa ctcccctttc tgttttaccg
     9001 caattaaaaa gggagtataa ataaagtcac aatcttcatc ccatgctaaa tctttcagtt
     9061 gtaagggata gatttcttcg ttttcaatat cctgaatagc atcaaaaaca gagaatgctt
     9121 caacttccaa taaatcttga cgatgtaaaa gatagcgcat atgtggatga tagggtagta
     9181 acacaatttt agactttatt ccttcccttt taaaaattct gatttgatgc aaaacatcat
     9241 cgaactccaa acgatgggtc gtttgatacc aaggaacaat atccacctgc caagattgat
     9301 tcatactttc taaaaatgga ataaaataat acatagctcc tcctaaaaaa tattactatg
     9361 ttcttcaaaa atctcttaaa gtagcatcag cgttgtctta agataaagta atagctaacc
     9421 tcagcaagta ttatctgcac cttcaaagtc cttctttgtg ccacctgttg ctagcttcct
     9481 aggattctct gtgatttcca ttgagtatta gacatcctgc aaatttaaat tcaatatatc
     9541 tgcattgctt ttaaataaaa tatcagaata taatttaggt acatttatat taaaatattc
     9601 tacaaattgt ttcacaggag aactattttc tctctacaag aggacgatag ctttcattca
     9661 atgttaatgc atttatttct tctttgacgt taaaaatcat tccattaaac atcaaaaata
     9721 agcccggtaa catacttaat tgcatataac gtggttcata cagaatgatt aacattggaa
     9781 ttcctgccat cagcaagata taaatagaac caatgacagc aaatcgtaac actaacctat
     9841 taatgtataa ggctgtatcc tctcctggat aaatatcata aatatattct ccggattttt
     9901 tcattttatc agcaatctgt tcaccattca tattaacaaa tgcgaatgca atccctaata
     9961 aaaatagaac aataatatat gtatacaccc atactggtcg ccctatcgta aattcagcta
    10021 tccaattgtc cacccatctt gtttttggta cgaaaatatg aagcaacatc aataaatact
    10081 gaggaataga aaccagcgat atcgcataca taaagggcat cccacctgct ggatttaaca
    10141 taatatcaaa gtaagagtaa cgtttgaaac gattatggat cataatttta ttgaccaaaa
    10201 tacgatatcg agctttttga acacgaaccg ctatatataa aaatgcaatc gatattagta
    10261 ataaactgat aataaatagt aaattcacat gtaaatctat tatacttctt actatatttt
    10321 caggaacact cactatcata ctcgacatca gaatcacaac agatcctcct actcctaaaa
    10381 gagaattaag atctgatagc caaactaaaa agaaggttcc tgatatcaaa agtagaatgt
    10441 ttaatattaa gactaaatca tgattaaccc cttcttgaat ggggaggttc aatgtaattg
    10501 ctaatgtctg aataaaagag atgataaagg taaggatcat tttcctacgt tcttggattt
    10561 caagcggtaa atttcctaaa ccaagcttct tagacatact aaacatctgc cataaaatca
    10621 ttgctgacat ccacggagat agaccaactg aaaatagtga aagactccga agatttccac
    10681 ctgtcatagc agtagaaaaa gccaaaaacg ctgcattacc acctaaaaaa ctcgtgtcat
    10741 ttacatttac aaacggtagg gttagtctac tccctaatat atatacaaat atgaaacaaa
    10801 tcgtccacat gactcgtttc acgacgactg atttcaattt tttcttcaag tttctctcct
    10861 acttttatta aaatgataac tcatgctgat tctaataaaa gaatctataa atcattttcc
    10921 taaatcatct cttacgctat atatccaata gttgcattat tgcatcagtt agtaattttt
    10981 ttgtaaaata accttctttc aaagcgtagc ttactttgga tacattttcc accatctgtt
    11041 gataaacttc tactgtagtt tcttctacaa gacgattggc ttcctccaaa ctatccacca
    11101 cataacctag gcctttttct tttatgaaac tggcgttaga tagataagaa ggaaccacga
    11161 ctggaattcc ggcagcaaga taggtactaa ctttatgaga gatattcaat ctatagtagt
    11221 cctcctcatc agttggattt tcgttagtcc cccatactaa gccaaaacca ccctctgata
    11281 aagcaaaaag caactctgga tctgttttcc aacctttaaa ggaaactctt ggattactat
    11341 tttcgtaatt agattctgaa aaaatatcga gaggagttga ataactccag ttggataaat
    11401 gttcaaagcg ttccacacta cccgcaaaat ataatttttt ctgaaaagat ggttgtttca
    11461 atgggtagtt atgaacatga tcccacattc cttggataat aatcttttga actgtcaatc
    11521 cctcctgaat caaacgttcc ttcatttttt ctgagggaac aactactaga tccgattgat
    11581 tgtacatttc aatatactca gacatcaagt aataattaga tggaaacata aggggtggta
    11641 cgtcatggat aaaggtaata attttcgtat ttaatatctt acatttcctg ataaaggctt
    11701 gatcatactc tctaccattc catgtaggag attgatagac aacaatatca ccgtagccta
    11761 acttagccaa aacaccgtct aagcgactgg tcaactctcc ttcactatcg ctataaatat
    11821 tgtaaaagta aaagctcagt tcatgaaagt ctaatttttt tgcaattttg acggtttcat
    11881 tctgggcgat taaggctgta ctttgaccag acataccgta aatatttgta atgtttatct
    11941 tcataatcct atttaaatcc ttacgactac ttgcttatta taaatttcat cctcaacgaa
    12001 ctgaatttct tgatcaaaat tatgctctgc tgtatgtttg tgtgagaatt tcactttgga
    12061 agttgctcct attttaaacc actcatattc agaatcaaca tgacctaaat caatcgcctg
    12121 tatgcctttc tggcttaaat gataagctaa aaccttggct gtaggaccaa gcatcaaaaa
    12181 cactaatttc ccatcagcgt acttctcaac cgtttcttga ataacctgaa ctttaccgta
    12241 ggcatttctc gaaggacaaa taatccgctc aactgactga gcattgtcaa aaaggtcatt
    12301 accaactcct gaacgtgaat tttcaccttc gacaatcaag atatctcgtt catcccaaag
    12361 ttgctttaat ttttcaaagt gagctactga agtagtctta tctttgaggt ccatataagg
    12421 acgagatata aaagtcgaac catagaaact tgctgtacaa tattgttgat aagcgtcttt
    12481 ataatgctct aagtgctttt tccaaaaatt aacagattca gaattgtaac gttccaagcc
    12541 ttcaaaaaca tcagaaagac aaaccagcaa ttctggagag ctttctagtt ggatcatact
    12601 tctaagctgt tctgccaatg tctcatcata gtcttgataa ggaatcccat gtcccatcat
    12661 aatatccatt tctccatctc catagcgaat aacagaagaa tggtgttcta gtatataatc
    12721 aagactctgc tgaatatcta gtacctttgg ataggattga aactttttta caggcaattc
    12781 tccattttga caataggctt caatagcaag aaccatctcc tcaggatgcg cttggtcata
    12841 aaggaactga ccttgttctc catggactac actttcaaaa gcaaatactg gttttcctgc
    12901 ttggcgaaaa cgctcaataa ttccatcaac ttcaatatca gcattgatat ccagtaagaa
    12961 gtcacagcct tcaactaagc tatcaatcaa aggtggttgt cctgcaatat ctgataagac
    13021 agagacattt gggtaggcta gtagatctgt aatactatcc gctaccataa caggagctgc
    13081 tacataaaac ttgacatctg gtaaattttc aatcaagtaa cccatatttc tcaagtcact
    13141 tgagaaggta tagactaggg ctgaatattg aacccctgtg tactgactca cctgatcttt
    13201 tgtcagagaa ggcgttacct gactcatgtc tgaccaatct tgggcattat aataccacca
    13261 gacatctcga tagatggagc attcatacag tccccaaggc tttctctcgg ttagataatg
    13321 aataatcggt ggataagtac cagactctgg tcgataatct gagaagtgtg tgtgcaaggt
    13381 aatacagtta tatttaaagt ctaaagctaa ccaacgatct ttaaataaga gattcaagat
    13441 actttggtca ctttgagcaa ccttatcatg caactcatta gtcatttcaa tcagttgttt
    13501 gcgaacttct tcttgcttcc aaaggcgatt attaatgagc atcacacctg aattaaaaat
    13561 atgttcacca aaataaattt gtccacccaa atctttaact gccgctaagg gatagtctcc
    13621 caattcaaga tcaaatagag gacttaagtc tcttgtgaca accaaatcac agtccagata
    13681 taagacctta gcctcctcaa caaaatccga aataaagtaa cgtaaaaata ctgcatagtg
    13741 aatattggtc ttatattggc taatatgaga actattgaca cgggcattga cgatttcaca
    13801 gtctagcttg gtcaacttac gattgagatt ataaaaccat tctgtcggaa aatcgctatt
    13861 aatcagataa aaacgaagac ctcgattgtg gcagcaaatc gatttgattg tcgttaatac
    13921 cttatctgca tattgataat tagcaccgaa tacgattgct ttcgtttcca ttttatcact
    13981 ctttaacttt ttaattactt ttatcatttc cagaggcgat tgagaaggaa caactatttc
    14041 ttccaattga tttttattgg tcacatcaaa agtcaatact ggtctacctg cactggtata
    14101 gcgattgacg atgaagtcca tcgaacttcc cttatggata tccagatagg catctgactt
    14161 ctcaatcatt tcatcaatca ctgccccaac catgctggga tataaataaa cattgggata
    14221 tttatctaaa gccaaaagaa tgtcacccat gtctgtataa gcaccaatat ggaaagcaat
    14281 atctagcaaa gattgagcga gttcatcaat atacagcaaa tcctgagaat ccgtaaatgt
    14341 aaataggttt atatcgtgaa aataataaac cctcttaaca gcgaaacgtc cttgataatg
    14401 gtcagaaatc tggtcaaaag tgacatcgtg aaaagaccac cataaatctc gatagcgata
    14461 gcccatgaga gtagtccatg gttttcgata ggtcgtataa tggatgatca aaggttcttc
    14521 atccaactca aagtgtgaat cccaatggct ataaaaagca ataatatcat gaccaacttg
    14581 aaaattaaaa cgcttatcca actctagcca atgattctgg aagactaaat tgaaaatagt
    14641 ttgatctcca ttgaacccat ctgtgtcagt atgatcaaga tatgacatat actccactgt
    14701 cttatcaaac aacatggaag taacatcctt ttctcgccac ttttgacaat caatgaccag
    14761 catccctgaa ttaaatccat taccatcaac atcccttact gctgctaaag agtagtctcc
    14821 aagactcagt tcaaataatg gactcaaatc tccattaaca ataatatcac tgtctaaata
    14881 gactactcta tcttctgtaa tcagtcgtga aattaagtat cgagcgtaag ctatagggga
    14941 tatatgctcc tgtgttttcc actcagcatc aatcgcatca ccgatataaa tatcctccac
    15001 aacactacct aatttctcca cttgaatttt gagttcttgg agccaatcgc taggaatatc
    15061 ctgatgcaga atataaatct taacattttg attataatac aaaatagact ttatcgtcgt
    15121 aagtatcgga gtaagataat tcttatcccc agcaagtaca attgctttca tatgaatcct
    15181 ttttacttta ttatattgaa acgcctcttt aagtcaatcg acattagaaa cacaacattc
    15241 tacctaaaca tactattaaa ttgaaaatta ttatgctata aatttaatgc tgatacttat
    15301 tgatagcctc tacattttca attcttttac acttctaatc aattcatcta tttcatctac
    15361 tgtaaaaact gtgctttccc cattgaaaaa atgattggtg caatcaaatg aataaattgt
    15421 tttccctcgt ctaaccattt cctgtaacat ttggtccata gctggtccgt aattaatatc
    15481 taagcaaata tctgttttat ctatgatatc ctgcttcatt ttagggtcag cacatggata
    15541 aatgtaacaa ttggaatagc gttgcaactc gataacatta ggggaaaaat atgttggagc
    15601 tacaatatga aattggacat ctggtaattt ttcaagtaaa taacctatac tctcgatgtc
    15661 tcctgtattt gtaaaaatac ttacatgttt ggatataggt gaaatcaact ctaaaaatgt
    15721 ttctttcaaa acatgagttc gtaataaaat atcgttccaa tttaagccgt agtagaacca
    15781 ccaaacatcc ctaaaacgat taaagcgaaa atgcttccac ggtttattct ctgtggtgta
    15841 gtgaataata cacgggacac cttcaaataa ttcgtaccaa tcataatctc ccatataata
    15901 tcgatgggca tcaacaccaa cttgcaaatt atatgttata tccaagcgtt tccatctatc
    15961 tttaaacaat atattgaaaa ttccctgatc tccgtataca tgttcatgat gagctatagt
    16021 taactcaaac aactgtctgt aaatatcttc ttcacgccac ctattcgtat caattagtag
    16081 tacgcctgaa ttaaattcct catcagtagt tggaatatct ggaacaactc caagtgggta
    16141 gccatccaaa tcaatatcaa acaatgctgt caaactagaa gttactacaa tatcactatc
    16201 aagatagaga accttctttt caaaaacaaa atttggaata aaatatcgaa gataggttgc
    16261 agaactaagg tgaggtgtag gaagatggaa gtgactaatc gtatcatctg tgatttttat
    16321 atttataatc tccgaattta atacagatag tcttttgttc atcaattgaa accactccgt
    16381 aggaaaatca ctgttaaaaa tataaaatct tatatcccta ttatgactac agactgactt
    16441 tatcgtcgtt tccaccttat ccatataatt gctatcagct ccaagtacta tggctttttt
    16501 acttgcctta tccgtcattc aatatcctcc attcttactt tgatttacat ctactcttta
    16561 aacaaatcta gtctaaacaa aatttctcta tactcatcag tatctgtaaa gttataattt
    16621 tcacataagt acttatattc attcaggata tttataaaac gagttctcat aatactggta
    16681 tcaatacctg caagaagcaa atcagcaagt ttagaactaa aaacctgtag gatatcctgt
    16741 acccaagata gatcaaattg tgaagtcatg atactccctt ttcgaacacg ataaatataa
    16801 agattatcat ttacgaaaat tgttttctga ctttttatga acaatctatg aatcgttgct
    16861 tcatcatcaa agcgccgacc attagtaaat ggaacttgca atagcaaatc ttttttaaac
    16921 aacttaaaca caggcataat aaaagctgaa gcatttaaat gccactttcc agcttgacga
    16981 tcaatcaatt cttgagcgga taattcctca atacaaaaat ctctttccaa aacatacaat
    17041 ttatactgac catcattttc atcataaaga aaataatttc caattacgat gtccgctcca
    17101 gtctcttcta cttgtctata aagcgtttcc accattcttt tttcagcaat atcgtctgag
    17161 tctacaaaaa ggacatactc accgagtgct tgagtaacac cgaaattttt agccagagct
    17221 gcacctctat tttctgtatg aaacacacga gcacgatcat ctatttcagc aaatctatca
    17281 catatctctg ctgaagcatc tgtagaaccg tcgtttacca gaactatatc cagatttgta
    17341 taggtctgat ttagaacact ttgaatgcac tcttccaaat aattttccac attatacaca
    17401 ggtataacaa cactaactaa atctttcaat tctactcctt ttcatactta ctctcattcc
    17461 ctcaacttcg cttaactacc gcaagtgaag aaacacaata tccaatcacg atttgagaaa
    17521 tccatgaatt tctaggctat gttttgatac caccacattc tatctttata cctcaactaa
    17581 aacaactcgc taaactaact tactctcaca aaaatagcat tcaaaacaat tataccaagt
    17641 aaaaaaacga atgttaaaaa ttagctccat tagaactcat tttatgacta cctagttctg
    17701 agtaagtatt atcttaaaac tgaactacta gaactttttc tctcattttg taaaacagac
    17761 aatagttcaa attattttaa tgaaaaggta ttcactaaaa agtcatactt aattaaaatc
    17821 aaagtgtact ttttaatcga cagttgcttc agaaatagcc tagtccaagt atatacttta
    17881 acatccaaca gttcttatag gtatgattat attctggaga gtcaacaaaa ggctcctaat
    17941 caagactata atttatgtgt ctacaaggcg caaatttata atctttttga tttttaatga
    18001 gtagcaatat aaaacttcct actataaact ataccatttt ttgtctaatc ataaagaagt
    18061 atctacgcta tattttccat caaaaaaact ccaaaagttt ttctatttag tctagcaatc
    18121 tctttcaact gcgaaagtca atattagtct tcatcatctc ttttacgacg tttggcaacc
    18181 aatcctaaac ctgttaaacc aagtatcaat ccaagaagtc ctgatttcac agactgtttc
    18241 tctcctgtat ttggtaattc ctgtcttgaa ttggttattg tctcttgtgg tcgagaatta
    18301 gttgatccac ttgtacttgt tgactcagag gtacttactg acgtacttgt actcattgtc
    18361 tctgacgcac ttgtcgacgc tgaagccgat gtacttgctg acgtgctggc actggttgac
    18421 gctgaagccg aagcactcgt tgatgctgaa gccgaggcgc tggtgcttgc tgaggctgac
    18481 gcactggtac ttgctgaggc tgacgcactt gtcgacgctg aagctgatgc actggtgctt
    18541 gctgaggctg aggcacttgt gcttgctgaa gcggacgcac tcgttgatgc tgactcagac
    18601 gcactcgttg atgctgaagc cgacgcactc gttgatgccg attcagacgc tgaggtgctt
    18661 gtgcttgctg aggtcgacgc act
//
LOCUS       DAVDHC010000041        18333 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVDHC010000041 DAVDHC010000000
VERSION     DAVDHC010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18333
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.041"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..309)
                     /locus_tag="VUR43_001917"
     CDS             complement(<1..309)
                     /locus_tag="VUR43_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5413559.1"
                     /translation="MAYSIDFCKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQVKGTKPRKVDRDRLKNYLTDNPDAYLTEIASDFGCHPTTIHYALKAMGYTR
                     K"
     gene            480..635
                     /locus_tag="VUR43_001918"
                     /pseudo
     CDS             480..635
                     /locus_tag="VUR43_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            835..4110
                     /gene="rexB"
                     /locus_tag="VUR43_001919"
     CDS             835..4110
                     /gene="rexB"
                     /locus_tag="VUR43_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET5413560.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMIFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            4107..7757
                     /gene="addA"
                     /locus_tag="VUR43_001920"
     CDS             4107..7757
                     /gene="addA"
                     /locus_tag="VUR43_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET5413561.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAANELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SDSFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLAHVVAISKEKNGRALTNASRKADLKPLANAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLPRFIRMIDQVLEAQHDLASVVVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVKVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            7972..9150
                     /locus_tag="VUR43_001921"
     CDS             7972..9150
                     /locus_tag="VUR43_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413562.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNVIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDYRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            9359..14986
                     /locus_tag="VUR43_001922"
     CDS             9359..14986
                     /locus_tag="VUR43_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET5413563.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIEIKIDFQEEI
                     QENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKG
                     ETEVQPESPDTVVSDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGAIVE
                     PAVQPALPEAVVSDKGVPEVQPELPEAVVSDKGVPEVQPELPEAVVSDKGEPEQVAPL
                     PEYKGNIEQVKPETPVEKLQEEEPEKTIELRSVSDVELYSYEANQSKQHTILDKVPDN
                     KSAYFIKVKSAKFKDVLLPVSNIEDTTKDGKVVYKITARLEHLKQSVDNQYQDNFTYY
                     LPKVVQNDGPIYTSFKKLVTDMNSRPDGTFILGATMNAREFELGENQESYVTKNFTGT
                     LIGSHQGKHYAIYNLKKPLFNTLNNAAIQDLTLKDVNISGKNHVASVAMEATNSSTLD
                     NVHANGIIAGELGIGGLVQKVDNSTVRNSSFTGRITNTFVTTSQYAIGGLVGQLTGAN
                     ARVAHSISTVVISSNGEHSNQTIGGIVGIVENNATVENSYAEGEINNAKPFARVGGVA
                     GSLWTQEGGTDNNTGRLTNVLSDMNITNGNAISGYHFNGIKETNVYSNKENKVVNVQA
                     VGDEVMSVDSTVERGTEIEKTSVQAKKDEITKKHTITVEDFTNSVKQDVDYTKAAHYQ
                     STREVAYKNIEKLLPFYNRDTIVKYGNQLSTDHNLFKKELLSVVAMKNDEVVSDITSN
                     KNSINHLLLHYKDGTSEKVDLTYNSDFANLAEYNIENTGLVYTPNAFLKNYTPIIDRV
                     KNDLTAVPYNPTALKNLLGISDNVKLTELYLDEQFTKTKEHLTETLKKLLSADAAVSG
                     NNDIIDNYIVDKIKRNKEALMLGLTYLERWYDFKFDKASAKDLLMFHMDFFGKGNTSP
                     LDAIIELGKSGYNNLLAKNNVVTYNALLTNNYGTKDLFSALEGYRKAFAPHQTNNEWF
                     KSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSATWKYRNMVLPLLTLPEKS
                     VFVISTISSLGFGAYDRYRNSEHKAGKDLNDFVEENARETAKHQRDHYDYWYRILDDN
                     AREKLYRNILLYDAYKFGDDNTVGKATEVADFDNPNPAMQHFFGPVGNKVGHNQHGAY
                     ATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYGRRSGLGPEFFAKGLLQAP
                     DHPDDATITINSILKHSKSDSTESRRLQVLDPTTRFNNADDLKQYVHNMFDVVYMLEY
                     LEGNSILKLDTNQKQQLLRKVTNEYHPDPDGNKVYATNVVRNITVEEVERLRSFNDLI
                     DNNILSSREYASGKYERNGYFTIKLFAPIYAALSNDDGTPGDLMGRRMAYELLAAKGF
                     KDGMVPYISNQFEADARANNKTITSYGKTKGLVTDTLVLQRLFNGQYNTWSDFKKAMY
                     KERQDKFNKLNKISFKDPSQPWTRNIIKTIHSVNELQNLMNEAVRKDTETPHWYNYNP
                     EIDSAVHKLKRAIFKAYLDQTNDFRSSIFENKK"
     gene            15038..15214
                     /locus_tag="VUR43_001923"
     CDS             15038..15214
                     /locus_tag="VUR43_001923"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET5413564.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            15678..15851
                     /locus_tag="VUR43_001924"
     CDS             15678..15851
                     /locus_tag="VUR43_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413565.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVRLES
                     SGDLILKELGGAL"
     gene            15848..16627
                     /locus_tag="VUR43_001925"
     CDS             15848..16627
                     /locus_tag="VUR43_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET5413566.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSR
                     EKGRLANKIYLGELSSTPVASSNRPSVKKRLGQVENETAPVSYSAPSETEVSETEISE
                     TESLFIEDEEDRNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            16726..18084
                     /gene="dcm"
                     /locus_tag="VUR43_001926"
     CDS             16726..18084
                     /gene="dcm"
                     /locus_tag="VUR43_001926"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET5413567.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEFHDIRDVSDDEFKKLRGKVDVICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQVLNSKDFGVPQNRE
                     RVFIIGHSRKKGTRLLFPFRREGQATNSETLKILGNLNPSKSGMSGKVYYSEGLAPTL
                     VRSKGEGFKVAIPCMTPDRLDKRQNSRRFKENQGPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGVLIDGQFYRLRIRR
                     ITPKECFRLQGFPDWAFEAARKVSSNSQLYKQAGNSVTVPVIAAIANKLKEIEEKDES
                     IK"
     gene            18068..>18333
                     /locus_tag="VUR43_001927"
     CDS             18068..>18333
                     /locus_tag="VUR43_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413568.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQIFLMPNYPCEFGVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGADAFVDDHQNL"
BASE COUNT         6077 a         3356 c         3786 g         5114 t
ORIGIN      
        1 ttttcgagtg tagcccatag ctttgagcgc atagtggatg gtagttggat gacagccaaa
       61 gtcagaagct atttcagtca aataagcatc tggattgtca gtaagatagt ttttaagtct
      121 atctctatca acttttcttg gttttgttcc ttttacttgg tggtttagct ctcctgtttt
      181 ctcttttagc tttaaccagc cataaatggt attacgtgag atttggaaaa cgtgtgatgc
      241 ttctgttata ctacctgttc gctcacaata agagagaact tttttacaaa aatctattga
      301 atatgccata aaaagattat accacattgt gtactatttt tggttcattt tactatagta
      361 gattgaaata agatacgaac agcttgatta gggaaatcaa attaatttct agcaatattt
      421 tagcatccac ggtgtactat tatagtttca atttactata gttcaatcat tctatcaaga
      481 atattgaata tataaaggca cgtaatatta aaacttcttc tgatatcgaa ttagagtccg
      541 atgttgatgg cgataaatca gacaatctac ccgtcgacat taagatactg ggacaacaca
      601 ttgaagtgta ttccgtacct aagaaacaat cataaaactc aaagtcttgt taccgaggct
      661 tttttattat gtgattttca gtagccagac ttattctatc taatacaagt aaagctaagt
      721 atttaagatt tagcagatga tgaagaaaag aaaggatggc ctaaatattt taacagattt
      781 acgaggctaa tcatggtata atatagggtg atgaaaaatt ccaacgaggc tgagatgaaa
      841 ttactttata ctgatattcg aacttctttg acagaaattc taacaagaga ggcagaagag
      901 ctagttgcag ctggcaagcg ggtcttctac attgccccca actctctttc ttttgaaaag
      961 gaacgcgccg tgctggaatg cttgtcccag caggcttctt tttcgattac cgtcacgcgc
     1021 tttgctcaaa tggctcgtta tctggtcttg aatgatttac cagctaaaac tactcttgat
     1081 gatatcggtc ttgggttggc cttttacaaa tgccttgccg aactcgatcc caaggacttg
     1141 cgtgtttatg gcgctattaa gcaggatcct caattgatcc agcagttaat tgagctttac
     1201 catgagatga ccaaatctca gatgattttt ttggacttgg agaatttaac agatgaggat
     1261 aagagggcgg atttactctt gatttttgag aaagtaacag cctatcttaa tcaagggcag
     1321 ttagcccagg gaagtcagtt gtcccatttg attgaggcta ttgagaatga caaggtaagt
     1381 agtgatttta atcaaatcgc cttggtcatt gacggcttta ctcgtttttc tgctgaggaa
     1441 gagcgggttg tggacttact tcacggcaaa ggtgctgaga ttgttatcgg ggcttatgct
     1501 agtaagaaag cctataccag tccttttagc gagggcaatc tctaccaagc cagcgtaaaa
     1561 tttctccatc atctggcttc taaataccaa acgcccgctc aggactgttc tcaaactcat
     1621 gagaagatgg atagttttga caaggcctct cgtttgttgg agtcttctta tgacttttca
     1681 gaactcgctt tggatgtcga tgagaaagac cgtgaaaatt tacaaatctg gtcttgtttg
     1741 acgcaaaagg aggagttgga gctagtagcc cgtagcattc gtcagaaatt acatgaaaac
     1801 tcagacctga gctacaagca ttttcgtatt ctcttggggg atgtagcttc ttaccagtta
     1861 tctctcaaaa ccatttttga ccagtatcag attccttttt atcttggtag aagcgaagcc
     1921 atggctcatc atcccttgac tcagtttgtc gagtctattt tagctttaaa acgttaccgt
     1981 tttcgtcagg aggatttgat taatcttctt agaactgact tgtatactga cctcagtcag
     2041 tctgatattg atgcttttga gcaatatatc cgctatcttg gtattaatgg cttgccagcc
     2101 tttcagcaaa ccttcaccaa atcccaccat ggaaaattta atcttgagcg tttgaatgtc
     2161 ctccgcctga gaattttagc acctcttgaa accctctttg ccagccgaaa acaaaaggct
     2221 gaaaacctcc tacaaaaatg gagtgtcttt ctaaaagaag gagctgtgac caagcagtta
     2281 caagatttga caaccacttt ggaagctgta gaacaggaaa gacaagccga agtttggaag
     2341 gctttctgcc atgttttaga acaatttgcg actgtttttg ctggttcaca ggttagtctg
     2401 gaagacttcc tagccttgct ccattctgga atgagtttgt cccaataccg taccattcca
     2461 gcaacagtgg acactgttct ggtgcagagt tacgatttga ttgcaccatt gactgctgac
     2521 tttgtctatg ctattggact aactcaggac aatttaccaa aaatttctca aaacaccagt
     2581 cttctgacag atgaagaaag gcaaaatcta aaccaagcga ccgaagaagg cgttcaatta
     2641 ctgattgcca gcagtgaaaa tctcaagaaa aatcgctaca ctatgctttc cttggtcaat
     2701 tctgctcgta agcagttgtt cttgtcggct ccaagccttt ttaacgaaag tgaaagtaag
     2761 gaatctgcct atcttcaaga gttgatccat tttggattta ggcggagaga gaagaggatg
     2821 aatcacaaag gactgtctaa ggaggatatg gggtcctatc acagtctttt gtctagtctg
     2881 gttgcctatc accagcaggg tgagatgagc gatactgagc aagatttgac ttttgtcaag
     2941 gttctgtcgc gtgtcatagg taaaaaacta gatctgcaag gtctggaaaa tccagccatc
     3001 ccaatcagtc caagcagcaa gaccttagcc aaggacacct tgcaagctct ctatcctgcc
     3061 aaacaggagt tttacctgtc tacgtcgggt ttgacagagt tttatcgcaa tgaatacagt
     3121 tatttcctac gctacgtttt aggcttgcag gaggaattac gtttgcgtcc tgatgcccgt
     3181 agtcacggga atttcttgca tcgtatcttt gaacgcgcct tgcagttgcc taatgaagat
     3241 tcctttgacc aacgtctaga acaagctatt caagaaacca gtcaagaacg cgaatttgaa
     3301 gctatttatc aagaaagttt ggaagcccag tttaccaagg aagttttgct tgatgttgca
     3361 cggacaactg gacatattct ccgacacaat ccagccatcg aaacaatcaa agaagaagca
     3421 aattttggtg gaaaagacca agcctttatt caattagaca atggacgcag tgtctttgta
     3481 cgaggcaagg tggaccggat tgaccgtttg aaagctaatg gagcgatagg agtagtagac
     3541 tacaaatcca gtctgactca gttccagttt cctcatttct ttaatgggct caattctcag
     3601 ttaccaacct atcttgctgc cctaaaaaga gaaggggagc agaacttttt cggcgccatg
     3661 tacttggaaa tggctgaacc tgtccaatct ctgatggcgg taaaaagtct ggcaggagca
     3721 gtggtagaag ccagcaaatc tatgaaatac caagggctct tcttggaaaa agaaagcagt
     3781 tatttaggcg aattttataa caaaaacaag gcgaatcaac tgacagatga ggaatttcag
     3841 ctcctactgg actacaatgc ctatctttac aagaaagctg ctgagaagat tttagcaggc
     3901 cggttcgcca tcaatcctta tactgaaaat ggcagaagca ttgccccata cgtccagcaa
     3961 catcaggcta ttacaggctt tgaagccaat taccatctgg gccaagcccg tttcctagaa
     4021 aagttggacc tagctgatgg caagcgtctg gtcggagaaa aactcaagca agcttggctt
     4081 gaaaaaataa gagaggagtt gaatcgatga agcttattcc ctttttaagt gaggaggaga
     4141 ttcaaaaact gcaagaagca gaagcaaatt cgagcaagga acagaagaaa actgccgagc
     4201 aaatcgaagc tatctacact tctggccaga atatcctggt ctcagcatcg gctggttctg
     4261 gaaagacctt tgtcatggca gagcgcattc tggaccaatt ggcgcgtggt gtcgaaattt
     4321 ctcaactctt tatctcaacc tttaccgtca aggctgcaaa tgaacttaaa gaacgtttag
     4381 agaaaaaaat cagcaagaaa atccaagaaa cagatgatgt cgacctcaaa caacacttgg
     4441 gacgccagtt ggcagaccta ccaaacgctg ccatcggaac catggactct ttcacacaaa
     4501 aattccttgg caaacatggt tatctgcttg atattgcacc taatttccgt attttacaaa
     4561 accaaagcga gcaacttctt ctcgaaaacg aagtctttca tgaggtcttt gaagcgcatt
     4621 accaaggtaa acagaaagag acctttagtc atttgctgaa aaactttgct gggcgtggca
     4681 aggacgaacg gggtctgcgc cagcaggtct ataaaatcta tgacttcctc caatccacca
     4741 gcaatcctca aaagtggctg agtgactctt tcctcaaagg ctttgagaaa gctgatttta
     4801 ccagtgaaaa agaaaaactg actgagcaaa tcaaacaagc cctttgggat ttggaaagct
     4861 ttttccgtta ccatctggat aacgatgcca aggagtttgc aaaggctgcc tatttagaaa
     4921 atgttcagtt aattctggat gaaattggct ccctaaatca ggagtccgat agtcaggctt
     4981 atcaggcagt gcttgcgcat gttgtcgcca tctctaagga gaaaaacggt cgagctctga
     5041 ctaatgccag ccgtaaggct gatttgaagc ccctggctaa tgcctacaac gaagagagaa
     5101 agacccagtt tgctaaacta ggacaattat cagaccagat aaccattctc gactatcaag
     5161 aacgttatca tggagacact tggaaactag ctaaaacctt ccaatctttc atgagcgatt
     5221 ttgtggaggc ttatcgtcag agaaaacgac aggaaaatgc ctttgaattc gctgatatca
     5281 gccattacac cattgagatt ttagagaatt tcccacaagt tcgtgagtct tatcaggagc
     5341 gcttccatga agtcatggtc gatgagtatc aggataccaa ccatattcaa gaacgaatgc
     5401 tggaattgtt gtctaatggc cacaatcgct ttatggtggg agatatcaag caatccatct
     5461 atcgtttccg tcaggcagac ccgcagattt tcaatgagaa attccaacgc tatgcgcaaa
     5521 atcctcaaga aggcaagctc attctcctca aggaaaattt ccgtagtagt tcagaagtgc
     5581 tgtcagcaac caatgatgtc tttgaacgtc tcatggacca agaggtcggc gaaatcaact
     5641 atgataacaa gcaccagctt gtttttgcca ataccaaact gactcccaat ccagacaaca
     5701 aggcagaatt tctcctctac gacaaggatg atacaggtga ggaagaagag agtcaaacag
     5761 aaacgaaact aacaggcgaa atgcgcttag ttatcaagga gattctgaaa cttcatcagg
     5821 aaaaaggtgt tgcctttaag gaaattgccc ttctaacctc cagccgcagt cgtaatgacc
     5881 agattctcct cgccctgtct gagtacggga ttcctgtcaa aactgacgga gagcaaaaca
     5941 attatctcca atccctagaa gtgcaagtca tgctagacac tcttcgtgtc attcacaatc
     6001 ccctgcaaga ctacgccttg gttgccctta tgaagtctcc aatgtttggt tttgatgagg
     6061 atgagctagc acgtttgtcc cttcagaaag cagaggataa agtccacgaa aatctctatg
     6121 agaaactggt caatgcacaa aaaatggcaa gtagtcaaaa aggcttgatt cacacagctc
     6181 tagctgaaaa actaaagcaa ttcatggata tcctagcttc ttggcgcttg tatgccaaaa
     6241 cccattctct ctatgacttg atttggaaga tttacaacga ccgtttttat tatgactatg
     6301 ttggggcttt gccgaatggt cctgctaggc aggccaatct ctatgcccta gcactgcgtg
     6361 ctgatcaatt tgaaaagagc aatttcaaag gtttgccgcg ttttattcgt atgattgacc
     6421 aagtcttaga agcccagcac gatttggcaa gcgtggtcgt cgcaccgcca aaagatgcag
     6481 tagagctcat gaccatccac aagagtaaag ggctggagtt tccttacgtc tttatcctca
     6541 atatggatca agatttcaac aagcaagact ctatgtcaga agtcattctc agtcgtcaga
     6601 atggtcttgg tgtcaaatat attgccaaga tggagacagg ggcagtagaa gaccactatc
     6661 ctaaaaccat caaactctcc attcctagtc tgacctatag gcagaacgaa gaggaattac
     6721 agctagcaag ctattctgag cagatgcgtt tgctgtatgt tgctatgacg cgggctgaga
     6781 aaaagctcta tcttgtcggc aagggttctc gtgaaaagct ggaatccaag gaatacccag
     6841 cagccaaaaa tgggaaacta aatagcaata ctagactgca agcacggaat ttccaagatt
     6901 ggctttgggc tatcagtaaa gtgtttacta aggacaagct caactttagt tatcgtttta
     6961 ttggcgaaga tcagttgacc agagaagcta tcggagagtt ggaaaccaag agtcctctcc
     7021 aagatagctc ccaagcagac aatcgtcagt cagataccat caaagaagct ctggaaatgc
     7081 tgaaggaggt gaaagtttat aatactcttc accgcgcagc tattgaactt cctagtgttc
     7141 aaaccccaag tcaaatcaag aaattctacg aaccagttat ggatatggaa ggtgtcgaga
     7201 ttgctggtca aggtcagtca gtaggcaaga aaatcagctt cgatttgcca gatttttcaa
     7261 ccaaagaaaa ggtaactgga gctgagattg gtagtgctac tcacgaactc atgcagagaa
     7321 ttgacctcag ccagcaacta acccttgcta gcctaacaga aacactcaaa caagttcaaa
     7381 ctagccaagc tgtcagagac aagatcaatc ttgataaaat tcttgctttc tttgacacag
     7441 tactcggtca ggaaattctt gctaataccg accatctcta tcgcgagcaa cctttctcca
     7501 tgctcaaacg agaccaaaag agtcaggaag actttgttgt ccgtggtatc cttgatggct
     7561 atctgcttta cgaaaacaaa attgttctgt tcgactacaa gacagaccgc tatgatgaac
     7621 caagtcaact cgtagaccgc tatcgtggtc agttagctct atacgaagag gctttatcac
     7681 gagcctattc gattgaaaat attgaaaaat acttgatttt actcggtaaa gacgaggttc
     7741 aagttgtaaa agtataactt atactctttg aaaatctctt caaaccacgt cagcttcgcc
     7801 ttgctgtata tatggttact gacttcgtca gttctatcca caacctcaaa acagtgtttt
     7861 gagctgactt cgtcagttct atctacaacc tcaaaacagt gttttgagct gactgcggct
     7921 agctttctag tttgctcttt gatttttatt gagtattaga aaggagacct catgacactt
     7981 ccagttagaa aatccctgca cgatgcagtt ttacaggctt cgaaagcgga tacttgggaa
     8041 caagctacca aggaatggaa tgaagtttcc ttgattttta acggtatcgg ccgtagcaat
     8101 tgtgtctgtg gaaatgtcat caaatacgct tatgaactct ttaacggtgt cacaggccaa
     8161 cgcctctttc caattggtag cgactgtgtt cgtcattttc atcgattgtc ccttgaccag
     8221 caattggaag aggaagaaaa actgctcaga aaggttgaaa atctaaccag aaaagctcag
     8281 aaaaaggaaa aaatcaaggt caataaaagt gactttgacg agcgacttct aaaatggctc
     8341 tgggaaaaag gtgttttcaa acccaatcgt ggcaatcaat ttgcgcctga gagagactac
     8401 cagcttttcc tagaagtctt tcagggagga agttggacca aggcggaacc aaagaaaaag
     8461 gctcggatgg aagaagtcct tgaaaagtgt atcaaaccct ttttacttgg gaaatcggat
     8521 gaccaactct accttgtcaa gctaggcaag gagaaaattg actacgaaca agaactccgt
     8581 atccaggcag agaaagaacg caagaagagg gataaaatcg ccaagcaata tgcagacaat
     8641 ctggttctag ccatgggacc cgcagagcgt gcttatcaag attactttgg ctttacagag
     8701 accctgactc aagaagaacg caagtgggaa aaaattcttt ttggtaaaaa tagagcagaa
     8761 cgggctatca aggccaaaca ataccaaaaa gagctggaaa aagaccaacg aattgccagt
     8821 caggatccaa ttgaaagaaa acagaaacag acttggctcc tcaattccta ttttcgtgag
     8881 cttcctgaag aaaaagctcg attttctagg ctcttattag aatatcgaaa aaatggtgaa
     8941 gtaccctttt caactgaata cctgtcagat catctcatcg actttttcta taaaatgaaa
     9001 gcctttgaat ttgaaatcgc accagaacaa gtccgagatt ttctaaaaaa aagcctgcag
     9061 gaagactatc gctcatcagc acaaggaagc tggatagaag gaattctcct caactgcctc
     9121 aaaccatttt tagaacgatt agtgatatga gtaacaccta ccgtgtaaat ttcatggtag
     9181 gtgttattgt acccccaaat aatataaaac aaagtatgaa agcgcatctc aattttaaga
     9241 cttttttgta aattaagagt ataattaagg tatactgcct tttctataga taatagataa
     9301 tacactaata taataaaggt ctttgtaaca tatataaatt ttatttcaag gaggaataat
     9361 ggaaaagtat tttggtgaaa aacaagagcg tttttcattt agaaaattat cagtaggact
     9421 tgtatctgca acgatttcaa gtttattttt tatgtctgta ttagctagtt catctgtgga
     9481 tgctcaagaa actgcgggag ttcactataa atatgtggca gattcagagc tatcatcaga
     9541 agaaaagaag cagcttgtct atgatattcc gacatacgtg gagaatgatg atgaaactta
     9601 ttatcttgtt tataagttaa attctcaaaa tcaactggcg gaattaccaa atactggaag
     9661 caagaatgag aggcaagccc tagttgctgg tgctagctta gctgctctgg gaattttaat
     9721 ttttgctgtt tccaagaaaa aggttaagaa taaaacggta ttacatttag tattggttgc
     9781 gggaatagga aatggtgtct tagtttcagt ccatgcttta gaaaatcatc ttttgctaaa
     9841 ttacaatacg gactatgaat tgacctctgg agaaaaatta cctcttccta aagagatttc
     9901 aggttacact tatattggat atatcaaaga gggaaaaacg acttctgatt ttgaagtaag
     9961 taatcaagaa aaatcagcag ccactcctac aaaacaacaa aaggtggatt ataatgttac
    10021 accaaatttt gtagaccatc catcaacagt acaagctatt caggaacaaa cacctgtttc
    10081 ttcaactaag ccgacagaag ttcaagtagt tgaaaaacct ttctctactg aattaatcaa
    10141 tccaagaaaa gaagagaaac aatcttcaga ttctcaagaa caattagccg aacataagaa
    10201 tctagaaacg aagaaagagg agaagatttc tccaaaagaa aagactgggg taaatacatt
    10261 aaatccacag gatgaagttt tatcaggtca attgaacaaa cctgaactct tatatcgtga
    10321 ggaaactata gagataaaaa tagattttca agaagaaatt caagaaaatc ctgatttagt
    10381 tgaaggaatt gtaagagtaa aacaagaagg taaattaggt aagaaagttg aaatcgtcag
    10441 aatattctct gtaaacaagg aagaagtttc gcgagaaatt gtttcaactt caacgactgc
    10501 gcctattcca agaatagtcg aaaaaggtac taaaaaaact caagttataa aggaacaacc
    10561 tgagactggt gtagaacata aggacgtaca gtctggagct attgttgaac ccgcaattca
    10621 gcctgagttg cccgaagctg tagtaagtga caaaggcgta ccagaagttc aaccagcgtt
    10681 gtccaaagca gttataaccg acaaaggtga gactgaggtt caaccagagt cgccagatac
    10741 tgtggtaagt gataaaggtg aacctaaaca ggtagcaccg cttccagaat atacaggacc
    10801 acaagccagc gctattgttg aaccagagca ggtagcacca ctaccagaat acacaggggt
    10861 acaagccgga gctattgttg aacccgcagt ccagccagcg ttacccgaag cagttgtaag
    10921 cgataaaggc gtaccagaag ttcagcctga gttgcccgaa gcagtagtaa gtgataaagg
    10981 cgtaccagaa gttcagcctg aattacccga agcagttgta agtgataaag gtgaaccaga
    11041 gcaggtagca ccattgccag aatataaggg gaatattgag caagtaaaac ctgaaactcc
    11101 ggttgagaaa cttcaagagg aagaaccaga gaaaacaata gaactaagaa gtgtttctga
    11161 tgtggaactc tatagttatg aagctaatca atcaaaacaa catacaatct tagataaagt
    11221 accagataat aaatctgctt atttcatcaa agtgaagtca gctaaattta aagatgtact
    11281 gctcccagtt tcaaacattg aggacactac aaaagacggt aaagtagtct ataaaattac
    11341 agctagattg gaacacttaa aacaatctgt agacaatcaa taccaagata attttactta
    11401 ttatcttcca aaagttgttc aaaacgatgg ccctatctac acatcattta aaaaattagt
    11461 aactgatatg aatagtagac ctgatggaac atttatactt ggcgcgacca tgaatgctcg
    11521 tgagtttgag ttgggtgaaa atcaagaaag ttatgttaca aagaatttca cagggacatt
    11581 aattggtagt catcaaggta aacattatgc tatctataat ttgaaaaagc cattattcaa
    11641 tacattaaat aatgctgcta ttcaggatct caccttgaaa gatgtcaata tttctggtaa
    11701 gaatcatgtc gcatcagttg ctatggaagc cacaaattct tcaactttag ataacgttca
    11761 cgcaaatgga atcattgctg gtgaactagg tatcggagga cttgtccaaa aagttgataa
    11821 ttctacagta agaaatagta gcttcaccgg aagaataaca aatacttttg ttacaacttc
    11881 tcagtatgca attggtggtc tagtcggtca attaaccggt gctaatgcta gggtagctca
    11941 ttctatttca acagtagtca tttcaagtaa tggagaacat tctaatcaaa caattggtgg
    12001 tattgttggt attgtagaaa ataatgcgac tgtagaaaat agttatgctg aaggtgaaat
    12061 aaataatgct aaaccattcg ctagagttgg tggagttgca ggttccctat ggacacaaga
    12121 aggcggaaca gataacaata ctggtcgctt gacaaatgtt ctcagcgata tgaatattac
    12181 aaatgggaat gcgatttctg gttaccactt caatggtata aaggaaacaa atgtctatag
    12241 taataaagaa aacaaagtag tcaacgttca agcagttgga gatgaggtaa tgtcagttga
    12301 ttccactgta gaacgtggta ctgagattga aaaaacatca gttcaagcta agaaagatga
    12361 gattactaaa aaacacacta tcacagtgga agatttcaca aattctgtta aacaggatgt
    12421 agattatacc aaggcagcac attatcaatc aacaagagaa gttgcatata aaaatataga
    12481 aaaattatta cctttctata atagagatac tattgtgaaa tatggaaatc aattatctac
    12541 tgatcataac ctgtttaaga aagaattgtt gtctgttgta gctatgaaaa atgatgaagt
    12601 agtctcagat atcacttcaa acaagaactc tatcaatcac ttactactac attacaaaga
    12661 cggaacatct gagaaagtag atttaaccta caatagtgac tttgcaaatc tggctgagta
    12721 taatattgaa aatactggtc tagtatacac accaaatgct ttcctaaaaa attatacgcc
    12781 tataatagac agagttaaaa atgatttaac tgcagtaccg tataatccaa ctgctcttaa
    12841 gaatttgtta ggaatctctg ataatgttaa attaacagaa ctttatctag atgagcaatt
    12901 cactaagacc aaagagcact taactgaaac tcttaaaaaa ttactttcag ctgatgctgc
    12961 tgtttctgga aataatgata taattgacaa ttacattgtt gataaaatca agcgaaacaa
    13021 agaagccttg atgctaggat taacctatct agaacgctgg tatgatttca aattcgataa
    13081 ggctagcgca aaagatttgc ttatgttcca tatggatttc tttggtaagg gaaatacctc
    13141 tccgctagat gcaattatcg aattaggtaa atctggctac aacaatctct tggccaaaaa
    13201 taatgtggtt acttacaatg ccttgttaac gaataactac ggtacaaaag atctgtttag
    13261 tgctttagaa ggctaccgta aagcatttgc accgcatcaa actaacaatg aatggtttaa
    13321 atcacagact aaggcttaca ttgtcgaaga aaaatccaat atcgaagagg tgaaaacgaa
    13381 gcaaggacta gttggcacta agtattctat tggtgtctat gaccgtatca ctagtgccac
    13441 atggaaatac cgcaatatgg tcttgccgct cctaaccttg ccggagaaat cagtctttgt
    13501 catctcgacc atctctagtc taggatttgg agcttatgat cgttaccgca atagtgagca
    13561 caaagcaggc aaggacctca atgattttgt tgaagaaaat gcacgtgaaa cagccaaaca
    13621 tcagcgagat cactacgatt attggtatcg tattttagac gacaatgcac gtgaaaaact
    13681 ttatagaaat attttgcttt acgatgctta taaatttggc gatgataata ccgtagggaa
    13741 agctacagaa gtggcagatt ttgataatcc aaatcctgca atgcaacatt tctttggacc
    13801 tgttggaaat aaagttgggc ataatcaaca cggtgcttat gctacaggtg atgcagttta
    13861 ttatatgggt tatcgaatgt tggataagga tggagctatt acttatacgc atgagatgac
    13921 acatgactca gatcaggaca tttatcttgg aggatatggt cgaagaagtg gcttgggacc
    13981 agagttcttt gctaaaggat tattacaagc accagaccat ccagatgatg cgaccattac
    14041 catcaactcc atcttgaaac attcgaaatc tgatagtaca gaaagtcgac gattacaagt
    14101 acttgatcca actacaagat ttaataatgc agatgatttg aagcaatatg tccacaacat
    14161 gtttgacgtt gtttatatgt tggaatatct cgaaggaaat tcaattctta aattggatac
    14221 gaatcaaaaa caacaacttc ttagaaaagt tacaaatgag taccatcctg atcctgatgg
    14281 aaataaggtc tatgcaacaa atgttgtcag aaatataaca gtagaagaag ttgaaagact
    14341 acgttcattc aatgatttga ttgataataa tattctttcg tctagggaat atgcctcagg
    14401 taaatacgaa agaaatggct atttcactat taaattattt gcgccgattt atgcagcatt
    14461 aagtaatgat gacggaacgc caggtgatct gatgggacgt cgtatggcct atgaactatt
    14521 agctgcaaaa ggctttaaag atggtatggt gccatatatc tcaaatcaat ttgaagcaga
    14581 tgctagggca aataataaaa cgattacctc atatggtaag accaaaggat tagtaacaga
    14641 tacattagtt cttcaaagat tatttaatgg acaatacaat acctggagtg attttaagaa
    14701 agctatgtat aaagaacgtc aggataaatt caataaattg aacaaaattt catttaaaga
    14761 tccgtctcaa ccttggacgc gcaatattat taagacaatt cacagtgtaa atgaactgca
    14821 gaacttaatg aatgaagctg tccgcaagga tacagaaact cctcattggt ataactataa
    14881 tccagaaata gacagtgcag ttcataagtt gaagagagca atctttaaag cctatcttga
    14941 ccaaacaaat gattttagaa gttcaatttt tgagaataaa aaatagtgtt tactattagg
    15001 aaataaagtt taaaaaggtg atgaagaaca aaccaagatt caagcaggaa ttcctactga
    15061 taatgaagta agttatgctc ttatttatca gcaggaaact cttcctgcaa caggttcatc
    15121 aacttctgcg cttacagctt taggcctatt agctgttggt agtttagttc ttttggttca
    15181 taatatgacg ggaacagttt tttgctccct ctgaaaagtc atcatttgat ggcttttttc
    15241 tatatagggt aaaaggctat catcggacaa aataaagaag gcatgatata atataaagta
    15301 gatttctatg tcataaaaca agaactgttt ggacatcatc catttgaaga ctctctatgt
    15361 tcaaactata gtaaaataaa ataggggatc taaatccttg ctacgaaagg aaaaaactca
    15421 atggctacta ttcaatggtt ggtctagaag atttaaaata ataaaacatt gtgaagtaga
    15481 ataaatactt gaaacccttg aatttcaagg gtttttgtga gtacagattt ttatttttca
    15541 cattgttata cgtgcttgat tgagcaataa tcatcaataa aaacattttt ttggtgttga
    15601 gtttggtgtt caaatattta ttatgttacg gaaaggaatt tcacaatctt tccgtttttt
    15661 tattttcagg aggaaaaatg acaaaagaat tacaatcatc acgctatatt gtcatttcat
    15721 ttttagtacg tgaaatggga attgacattg ttgaagccat ctctcttatg gctgaattag
    15781 aaaaaagtgg cttggttcga ttggaatcaa gtggagattt aatactcaaa gaacttggag
    15841 gagcgctatg aaacgaatta ccgcaaatca ataccaaacc tcagaacggt attacaaatt
    15901 acctaaaatt ctttttgagg atgagaaata tatggatatg aaactagaag taaaggtggc
    15961 ttattctatt ttaaaagatc gtttagaatt atctctcagt cgtggttgga tagatgaaga
    16021 aggagcggtt tatttagtat tttctaactc taaactgatg aaactgttag gttgttcgaa
    16081 gtcaaaatta ctgtctatca aaaaaattct taaagaatat gacttaattg atgaagtcca
    16141 acagtcttca agggagaaag ggagactagc taataagatt tatttagggg agttgtcttc
    16201 taccccagta gctagttcaa acaggcctag tgttaaaaaa agactagggc aggttgaaaa
    16261 tgaaacggcc cccgtctcat attcagcccc tagtgagact gaagttagtg agactgaaat
    16321 tagtgagact gaatctttat ttattgagga tgaggaggat aggaatactc aacctatctt
    16381 gaaaagaaaa gtagaaaagg tcacaaaata tgatcgagat tatatttggg gattggtaca
    16441 agatcaattt agacgagagg ggttttctga aacagccagt gaaattgcta tgactgattt
    16501 tgagagaatc tatcagtatg ctcttgacaa tgttcgcttt gttagacgag cggaagtcct
    16561 tgctgaattt gtgtttaatg gcttgtattc cgtttggaat aaccgtgtta gaaaaggagg
    16621 tggttaaatg tcgccaatcg agtggatatt agttatgctc attgtcattt caagtggagt
    16681 gacagttctg acaatgatag tcgataagaa aggggtgata aagaaatgag atttattgat
    16741 ttattttcag gtatcggtgg ctttcgactt ggaatggaaa gtgttggaca cgagtgtatt
    16801 ggattttgtg agattgataa atttgctaga gaatcttata aatccatttt tcaaacggaa
    16861 ggagaaatcg aatttcatga catacgagat gtttcagatg acgaatttaa aaaacttaga
    16921 gggaaagtcg atgtcatctg tgggggattc ccttgtcaag cattttcaat cgcaggaaga
    16981 cgattgggat ttgaagatac tagaggaact ttgttctttg aaattgctcg ggcggccaaa
    17041 caaatccaac cacgttttct ttttcttgaa aatgttaaag gcctactcaa tcacgataag
    17101 ggacggacgt tcaccacaat acttaccaca cttgatgagt tggggtttga tgttgagtgg
    17161 caggtgctta acagtaagga ttttggcgtt ccccaaaaca gagagagggt gtttattatc
    17221 ggacattcta gaaagaaagg gaccagactc ctatttcctt tcagacgaga aggtcaagca
    17281 actaactctg agactttaaa aatattagga aatttgaatc catcaaaaag tggaatgagc
    17341 ggtaaagtct attattcaga aggtcttgcg ccaaccttag ttcgtagtaa aggagaagga
    17401 tttaaagttg cgattccttg tatgacacca gatagattag acaaaagaca aaatagtaga
    17461 cgctttaagg aaaatcaagg gccgatgttt actttaaata ctcaggatcg tcatggcatt
    17521 gtcgttgttg gagatttacc gactagcttt aaggagacag gtcgtgtcta tggaagtgag
    17581 ggcttatctc caacactgac tacaatgcaa ggtggagata aaatccccaa aatactaatt
    17641 ccagaaccaa tccaatttct aaaagtccga gaggcaacta aaaaaggata tgctcaagca
    17701 gaaataggag attcaatcaa tttggagaga ccaagttctc agtatcgtcg tggtagagtt
    17761 ggaaaaggta tagcaaatac gttaacaacc agtgggcaaa tgggagtagt agtggctagc
    17821 tatgaaggcg aagataaaca agtttatcat gtagccggtg tcttaataga tggacaattt
    17881 taccgtttga gaatacgacg aatcactcct aaagagtgtt ttcgattgca ggggtttcct
    17941 gattgggctt ttgaagctgc gagaaaagtc tctagtaata gtcagctcta taaacaagct
    18001 ggtaatagtg taaccgttcc tgtgattgcc gcaatcgcaa ataaattaaa agaaatagag
    18061 gaaaaagatg aaagcattaa ataaagaatc aatactagat tgtgatgaat tagaaacaga
    18121 attacatgat gcagaaatca aacagctgga tgaacaaata tttttgatgc ccaattatcc
    18181 atgtgagttt ggggtgacat ttttagatga ttaccataaa aaacataatt acccactatt
    18241 ttacgaatcc taccttcaaa acgttatgga attccttgaa agtcaggata taaagaatgg
    18301 agctgatgcc tttgtagatg atcatcaaaa tct
//
LOCUS       DAVDHC010000042        17852 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVDHC010000042 DAVDHC010000000
VERSION     DAVDHC010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.042"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            227..1093
                     /locus_tag="VUR43_001928"
     CDS             227..1093
                     /locus_tag="VUR43_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5413569.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            1430..1987
                     /locus_tag="VUR43_001929"
     CDS             1430..1987
                     /locus_tag="VUR43_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET5413570.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            2208..3314
                     /locus_tag="VUR43_001930"
     CDS             2208..3314
                     /locus_tag="VUR43_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET5413571.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            3290..4681
                     /locus_tag="VUR43_001931"
     CDS             3290..4681
                     /locus_tag="VUR43_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413572.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            4678..5856
                     /locus_tag="VUR43_001932"
     CDS             4678..5856
                     /locus_tag="VUR43_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5413573.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNVNIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            6281..6514
                     /locus_tag="VUR43_001933"
     CDS             6281..6514
                     /locus_tag="VUR43_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5413574.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            6797..8746
                     /gene="mutL"
                     /locus_tag="VUR43_001934"
     CDS             6797..8746
                     /gene="mutL"
                     /locus_tag="VUR43_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET5413575.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEAFSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLFQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(9071..9538)
                     /locus_tag="VUR43_001935"
     CDS             complement(9071..9538)
                     /locus_tag="VUR43_001935"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET5413576.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEISLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(9539..10744)
                     /locus_tag="VUR43_001936"
     CDS             complement(9539..10744)
                     /locus_tag="VUR43_001936"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET5413577.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(10764..11399)
                     /gene="ribE"
                     /locus_tag="VUR43_001937"
     CDS             complement(10764..11399)
                     /gene="ribE"
                     /locus_tag="VUR43_001937"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET5413578.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSINGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(11384..12484)
                     /gene="ribD"
                     /locus_tag="VUR43_001938"
     CDS             complement(11384..12484)
                     /gene="ribD"
                     /locus_tag="VUR43_001938"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET5413579.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(12618..12732)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            12889..13482
                     /gene="ruvA"
                     /locus_tag="VUR43_001939"
     CDS             12889..13482
                     /gene="ruvA"
                     /locus_tag="VUR43_001939"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET5413580.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            13492..14055
                     /locus_tag="VUR43_001940"
     CDS             13492..14055
                     /locus_tag="VUR43_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET5413581.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWAQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            14052..14729
                     /locus_tag="VUR43_001941"
     CDS             14052..14729
                     /locus_tag="VUR43_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5413582.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKGIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(14884..15915)
                     /locus_tag="VUR43_001942"
     CDS             complement(14884..15915)
                     /locus_tag="VUR43_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET5413583.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(16170..16853)
                     /locus_tag="VUR43_001943"
     CDS             complement(16170..16853)
                     /locus_tag="VUR43_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET5413584.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(16865..17809)
                     /locus_tag="VUR43_001944"
     CDS             complement(16865..17809)
                     /locus_tag="VUR43_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET5413585.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
BASE COUNT         5525 a         2980 c         3457 g         5890 t
ORIGIN      
        1 ctaggggaac agttgtaatt agaaggtgat aggtatgaaa agtggcgttg aagctggata
       61 agtttataaa gagtttgaat gaagaaatga aaagtaaata agttgatgat gaattgcaaa
      121 aatagatttt atatacaatt tgtatctttc aaatcattga tttgaatttt agatttaatc
      181 atgttacaat taaaaatgaa atcaaataga agaggaagat gcaaacgtgg gcacactatt
      241 agcaacaaga ttaaaaaata gacgaaaaga attaaaaatg tctcagcgag aactagctga
      301 aggtatctgt aaacaggggc aaatcagtcg attagagagc ggagagttta ctcctggagc
      361 agatttcttg catgcccttg ctaagaagtt aaaagtcagt atggattatt tttttgatga
      421 gcaggttgta gagaaagttg aggagttatc agaatttaag aaattagcac agacatttat
      481 tacaaatcgc aattatgagt ctttgaaata tatatatgaa ttggagaatg taaaagctca
      541 ccgcctatct ttagcagata aaatctacat ggaatggata aaatctctga tagattttta
      601 tttttacgga cagaaagaag atgcgattgt acgattagag ggggtattat cacagttaag
      661 tgtatctgat ttgaactatc tccaagtttc aaacacccta ttcaattttt attatgatat
      721 tggagattta ggtcgtttca ataaaattcg tgaaaaacta gagtatcaag taaatcacct
      781 caatttgagt acaatcgaag agttagaact atctattaag tttaactaca acgtttgtcg
      841 ttatctatgg ttacagaaaa atattgaaga agctattact aaaattacag ctactataaa
      901 acaatgtaag gcttacagaa cgaattatct tttggctgat ttgtacttat tgatgggaaa
      961 tgtaagtgaa aatttttctt ctaaaagttc ggtgaaagaa tattttgaga cggcatattt
     1021 tctatacaaa cttgaggaga acatgtcaat gactctgaaa gttgagcatt acattgcaga
     1081 tataacagaa taatgaatac ggtgttcaag tgagcatcgt ttttcaaacc tagttcagat
     1141 acaaaaaagt atcaaacaaa aaaaaataaa aaaacattat aaaaacaatt gacaagctaa
     1201 ttttgaagtg ataaaataaa tgcaagaaaa caaaaggaga ggtatatgag aagtttgttt
     1261 aagaaaatag ttgctgtatt agttattggc ttaattctgt taggaattgc gagaacacct
     1321 caagttcata agatggctaa agggattgat cctggtcctg cgaattttat ttagaaatca
     1381 atttctacta attgagtact aattgagtat taatgggtaa aaagattgta tggataagaa
     1441 aaatttactt gtattggtta ctggttcggt aggtgccagt aatgtagata catacttata
     1501 ttatataaaa aaattctata atgttaaagt gatactttct gaaaattcta aaaaatttat
     1561 aagtaaggaa ttaattagtt atttttgtga taaagtttat gatgaaatat ttgttgaaga
     1621 ggtagttccg cacgtttttc tgccatatga atctgactta cttcttattt taccagctac
     1681 ggcaaatgtg attggcaaaa ttgctaatgg tattgctgat gatttagtta cagcaactgt
     1741 tttaaacttt aataaaaaaa taattttttg tcccaatatg aactctacta tgtgggacaa
     1801 tcacatagtt caaagaaatg tatcaattct aaaggagttg ggacatatat ttttatttga
     1861 gtctaaaaaa acatatgagg taggattgcg taaagcaata gattcaacat gttcaatgtt
     1921 acaaccacag tcgttagtaa aagaacttat caaattagaa aatattgtcc ttgaagaggg
     1981 acattaaaaa ctactgagaa tattaaggag gggaaaaaat ggaaaattca tcaatcgatg
     2041 tagatatgct gttggaagaa ttgacacaag aagcaatggt cgttgttgct gttgataagg
     2101 actgttaatt taaacttatg gcaatatatg aaaggttact ggatgtttta aattatgcag
     2161 gcagtagcct tttattatat acaaatggat aaagtaagga taatacaatg attaataaaa
     2221 aaatacaaca agttgttttg gaatcattac agaatttttt gaatgggaac ttcatttcgc
     2281 cttgtgtagt ctatgatttt ggcttgctgg aaactgtact tgatgaattt aaaaatcaaa
     2341 ttcctgtaac attcaattac caactttttt atgccgttaa agcaaattca aatgagaaga
     2401 tacttgaatt cttagtagat aaaattgatg gagttgatgt ggcgtcatta tctgaattag
     2461 atgtggctaa aaaatttttc ccaccaactc aaatttctgt taatggtccc gcattttctt
     2521 atgaaacttt atataatctg attaaaaaac aatataaagt tgatattaac tttttggaac
     2581 atcttcaaca attttcccca aaagaatctg ttggaataag agtaacggag ccagatgaac
     2641 ttaataatcg tatgagtcga tttggaataa atatttgcag tgataattgg actagtaatt
     2701 tacaaaatcc tttaattaca cgactgcatt ttcattttgg agaaaaagat gataaattta
     2761 ttgttaagtt agataaaata ttatttaagt tacaagaaat taataaactt agagaggtta
     2821 gagaaataaa tcttggaggc ggttttatga aattatttat ggaaaatcgt ttgaaagaat
     2881 tttttctatc acttatggaa atctataaaa agtacgatat tgatagtact gtgactacaa
     2941 taatagaacc aggtagtgca attacttcat tttctgccta tatgattact agcccagtta
     3001 atgttagtga ggtgaatgag cagcaggtta tcacgttaga cacatcaata tacaccaata
     3061 cattatggtt tgttccgcat attattacaa cgttaaattc aagtagtaaa gagcgttata
     3121 gtactattct ctatggtaat acctgttatg aacatgacaa gtataaaatg aaagtttcgc
     3181 ttccaaggtt aactcaaaat agcagtatag tgttttttcc tgtaggagct tatataaaaa
     3241 gcaatcattc aaatttacat cgtaatgatt ttatgcggga ggtatatttg tggacaaaaa
     3301 acttgacata ttagataaag ttaaggaata tttaggaaat aaaactactc aaattctgga
     3361 taatcaatat aaagaatttt tgaaacttaa tgatataagg cgagcgtttg gtatttcaga
     3421 aaaagtatta aacaattctt ttaattttac gagtaaagaa tttaatgatt taattaataa
     3481 cgaaaattat ttattcgaat atgcatgtag aattagagag gaatggagaa aaaaatgctt
     3541 taatcattct tatcgttttc tatgctcacc tataattaca gatgattttc ttaacacgaa
     3601 gacattgaga agtagccaaa ttgaatataa atatgagcga tatttatcga aaagttcgat
     3661 aggcgataga gcggttgatg gctttgtttc cttcaatact ttaacagcta atggtatgtc
     3721 tgctattaaa ctatgtcttg agatattaaa ctctattttc ttcaagaaga agattgattt
     3781 attatattca accggatatt atgaaacaag atttttatta aataatcttg ctaaatcagg
     3841 tattagttgc tatgaggtaa gtaattgtga attggataaa gataaatttt ataatgtatt
     3901 catgatggaa cccaatcgag ccgatttaac attacaaaaa actgatttca agatagtaga
     3961 atattttgtt aagtataaaa ataattcaat aaaagtcgtt attttagata tttcatatca
     4021 aggttctaat tttaaattag tagaattttt agagaaattt aaatttgcga atgtaattat
     4081 ttttgtggta cgatctttga taaaattaga tcaaatggga ttagaattga caaatggggg
     4141 aataatagaa gtgtttattc ctaatcattt gagaaagttg aaaaatttta ttgaagagga
     4201 attcaataaa tttagaaatt ctcacggagc taatctaagc ctctatgaat actgtttgct
     4261 tgataattct ttaaccttaa aaaatgattg gaactattct gatttagtta tgaaatttac
     4321 gagtaatttt tatgctgata taaaagactt gttcatggaa aattctgata ttgaaatcat
     4381 ccatgaagag ggagtacctt ttgtattttt agatttaata ggtgaaggta aaaaagaata
     4441 tgaaatgttt tttcaatggt taaacttctt ttacaaacag cttggaatca cattgtatgc
     4501 tagaaatagt tttgggtttc ggaatctaac agtagagtat tttggaatta ttgggacaga
     4561 aagatatata tttaagattt gtccaggtgt ttataaaggg ttaagttatt atttgatgaa
     4621 atttttatta aaatcttttt caaatgaata tttaaaaact actgatgagg ttaatagatg
     4681 aaaaatttga taaagttgct aataattaga ttgattgtta acttagcaga cagtgtattt
     4741 tatatagtag cattgtggca cgttagcaat aattattctt cgagcatgtt cttaggaata
     4801 tttattgcag taaattatct accggatttg ttactaatct tttttggacc agttattgac
     4861 agagtaaatc cgcaaaaaat tcttataata tcaattttgg ttcaattagc agtggctgta
     4921 atatttttat tattattaaa ccaaatatca ttttgggtga taatgagtct agtgtttatt
     4981 tcagtaatgg ctagctccat aagttacgtg atagaagatg tgttgattcc tcaagtggta
     5041 gaatatgata agattgtatt tgcaaattct ctttttagta tttcgtataa agtattagat
     5101 tctattttta attcattcgc atcattttta caggtggcag taggatttat tttattggtt
     5161 aagatagata taggcatatt tttacttgct ctatttatat tgttgttgtt aaaatttaga
     5221 actagcaatg tgaatataga aaacttctct ttcaaatatt acaagagaga agtgttgcaa
     5281 ggtacaaagt ttattttaaa taataaatta ttatttaaaa ccagtatttc tttaacgctt
     5341 ataaactttt tttattcatt tcagacagta gttgtaccga ttttttctat tcgatatttt
     5401 gatggtccga ttttttatgg tattttttta actattgctg gtttgggtgg tatattggga
     5461 aatatgctag cgccaatcgt aataaaatat ttaaaatcga atcaaattgt tggtgtattt
     5521 ctttttttga acggctcaag ttggttagta gcaattgtta taaaagacta tactttatca
     5581 cttattttat ttttcgtttg ttttatgtct aaaggagtct tcaatattat ttttaattcg
     5641 ttgtaccaac aaatacctcc acatcaactt cttggtaggg taaatactac cattgattct
     5701 attatttctt ttggaatgcc aattggtagt ttagttgcag gaacgcttat tgatttgaat
     5761 attgaattag tgttaattgc tattagcata ccttattttt tgttttctta tattttttat
     5821 acggataatg gattgaaaga atttagtata tattagaaat gtttatgttc attcaaaagc
     5881 ataatgacta taactgaaaa agaaaagtga tatctttaag gttgttcttc ttggtggtga
     5941 gattcgtgag acaacccaag cttttgtcgg aaagattacc aatgctttga tggataggat
     6001 gtactttagc aagatgtttt tagtggtaac ggtatcgtgg atggacgtgt aataacctct
     6061 tctttcgagg agtattttac taaaaaacta gccttggagc gttccccaga aacggactta
     6121 ctcattgact cttcaaagat ttggggagaa gattttgctt catctgttcc ttgaaaaaag
     6181 tcacagcagt catcacagac gatagtactg aacaaaacta tgaagagtta gaaatttata
     6241 cgcaggtgat tgtataaagg atctggaaat agataagaag ttgattagta ttgacctagg
     6301 tggtacaaat attaagatta ctgttctttc aaatgacggt gagattgaaa ctttgtggag
     6361 tattacaaca gatacaagtg agaaaggttc tcaaattata tcggacatca tcagttctat
     6421 taaaaataaa ttgaccgaac ggaatattcc tgatagcgac cttcttggaa tcggtatggg
     6481 aagttgctca tcatactttc cttgtaaatc ataggggcta taaactctcc gtctacttgt
     6541 cctacaacaa ttgaagtctg ctcaaaacgc cgtccgctaa tcttttcata gactttctcc
     6601 cttttaggag cctagctttc tagtttgttc tttgattttt attgagtata ccactatttt
     6661 actccctctg gcaaggtact ttgtctatgt ggagggattg ggctcctatg tggtggagct
     6721 tttctgttct ttctgaaata tggtataata gcactaatca atttctagga aaatagatac
     6781 agaaaggggc tgaaagatgt ctcatattat tgaattgcca gagatgctgg caaaccagat
     6841 tgcggctgga gaggtcattg aacgtcctgc aagtgtggtt aaagagttgg tagaaaatgc
     6901 cattgacgcg ggctctagtc agattatcat tgagattgag gaagctggtc tcaagaaaat
     6961 ccaaatcaca gataacggtt atggaattgc ccacgatgag gtggagttgg ccctgcgtcg
     7021 ccatgcgacc agtaagataa aaaatcaagc agatctcttt cggattcgga cgcttggttt
     7081 tcgtggtgaa gccttgcctt ctattgcgtc tgttagtgtc ttgactctgt taacggcggt
     7141 ggatggtgct agtcatggaa ccaagttagt cgcgcgtggg ggtgaagttg aggaagtcat
     7201 cccagcgact agtcctgtgg gaaccaaggt ttgtgtggag gatctctttt tcaacacgcc
     7261 tgcccgtctc aagtatatga agagccagca agcggagttg tctcatatca ttgatattgt
     7321 caaccgtctg ggcttggccc atcctgagat ttcttttagc ttgattagtg atggcaagga
     7381 aatgacgcga acagcaggga ctggtcaatt gcgccaagca atcgcaggga tttacggttt
     7441 ggcgagtgcc aagaagatga ttgaaattga gaactctgac ctagatttcg aaatttcagg
     7501 ttttgtgtcc ttgcctgagt tgactcgggc taaccgcaat tatatcagcc tcttcatcaa
     7561 tggccgttat atcaagaact tcctgctcaa tcgtgctatt ttggatggtt ttggaagcaa
     7621 gcttatggtt ggacgttttc cactggctgt cattcacatc catatcgacc cttatctagc
     7681 ggatgtcaat gtgcatccaa ctaagcaaga ggtgcggatt tccaaggaaa aagaactgat
     7741 gactctggtt tcagaagcta ttgcaaatag tctcaaggaa caaaccttga ttccagatgc
     7801 cttggaaaat cttgccaaat cgaccgtgcg caatcgtgag aaggtggagc aaactattct
     7861 cccactcaaa gaaaatacgc tctactatga gaaaactgag ccgtcaagac ctagtcaaac
     7921 tgaagtagct gattatcagg tagaattgac tgatgaaggg caggatttga ccctgtttgc
     7981 caaggaaacc ttggaccgat tgaccaagcc agcaaaactg cattttgcag agagaaagcc
     8041 tgctaactac gaccagctag accatccaga gttagatctt gctagcatcg ataaggctta
     8101 tgacaaactg gagcgagaag aagcattcag cttcccagag ttggagtttt tcggacaaat
     8161 gcacgggact tatctctttg cccaagggcg agatggactt tacatcatag atcagcacgc
     8221 tgctcaggaa cgggtcaagt acgaggagta ccgtgaaagc attggcaatg ttgaccagag
     8281 ccagcagcaa ctcctagtgc cctatatctt tgaatttcct gcggatgatg ccctgcgtct
     8341 caaggaaaga atgcctctct tagaggaagt gggcgtcttt ctagcagagt acggagaaaa
     8401 tcaatttatt ctacgtgaac atcctatttg gatggcagaa gaagagattg aatcaggcat
     8461 ctatgagatg tgcgacatgc tccttttgac caaggaagtt tctatcaaga aataccgagc
     8521 agagctggct atcatgatgt cttgcaagcg atctatcaag gccaatcatc gtattgatga
     8581 tcattcagct agacaactcc tctatcagct ttttcaatgt gacaatccct ataactgtcc
     8641 tcacggacgt cctgttttgg tgcattttac caagtcggat atggaaaaga tgttccgacg
     8701 tattcaggaa aatcacacca gtctccgtga gttggggaaa tattaaaagt ataaaaaagt
     8761 ctgggaaaaa ttttcaaaat cagaaaaacg cataaaatca ggtgttcaaa aaccttgatt
     8821 ttatgcgttt tatcatggaa atagttactt cattttttcc taattctttt cgaaactctt
     8881 tttaaacgac gtcagtttta tcagtaatct caaaacagtg ttttgagcta attttgccag
     8941 ttttgtctgt aacatcgaag ttgtgtttta ccactctgcg actggtttcc tagtttgctc
     9001 tatgattttc acagagtatt aaattgcgat tttgccaagt ttctttattc gtctaaaagt
     9061 agagtctgtt ctatgcgtct aatgtacgaa ttaggttgac catttcaata gctccttgtg
     9121 cacactcaga acccttattt cctgctttag taccagctcg ttctatggct tgttcaattg
     9181 tatctgtcgt tagcacacca aacataacag gaatttcgct atttaaactg atttgggcga
     9241 ttcccttaga tacctcgcta catacataat cataatgact tgtattccct ctaatgacag
     9301 ctcccaagca gataattgca tcatattttt tactttttgc catttttgat gcaatcagtg
     9361 atatttcaaa agctcctgga acccaggcta cctctatatc tttctcgttt acattctctc
     9421 ttttgagatt atctagtgct ccagataata attttgaagt tataaattca ttaaatctcg
     9481 ctacaacaat acctatttta atattgtttg ctactaaatt accttcataa gtgttcattt
     9541 atttttcctc catatttaaa atgtgaccca ttcgattttt ctttgtttct aaataaaaac
     9601 tatcgtaagg attggcttct atttcgattg atattctact ggaaatagta attccatatt
     9661 tttctaactg ttcaaccttg tcaggattat ttgtcagtaa atgaagtgac tgaagtccca
     9721 gatctttaag catttgtgct ccaatatgat attctcttaa atcaccttca aagcctaatg
     9781 caagattggc atcaagcgta tccatgcctt gatcttgtaa atgataggct tttaatttat
     9841 tgataagtcc aattcctcgt ccctcctgtc gcaagtaaag taagacaccc gaaccattct
     9901 caacaatcat tttcatagct ttatcgaatt gctgtccaca atcgcaacgt aaagagccta
     9961 aaacatcccc tgttaaacat tcggagtgga cccgacataa tacattggct tcatcctcta
    10021 tgtttcccat aataagagca agatgatgtt ccccatttag tttatctata tagctaattg
    10081 ctttgaaatt accgtatcta gtaggcatat tgacagttga aactcgttct accagctgat
    10141 catatacttt tctatattct tgtaattctt tgatggtaat tagtggaatg ttgtgtttct
    10201 tcgagaactg aattaaatca tctgttctca tcattttgcc atcatgattc attatttcac
    10261 aacataggcc acactctttt agtccagcta attttaataa atcaacagtt gcttctgtgt
    10321 gtccatttct ttctagaaca ccaccttttt ttgcaattaa aggaaacatg tgtcctggcc
    10381 tgcgaaaatc agagggtgtt atatcttcag ctacacacat acgtgcggtc agtcctcttt
    10441 cctcggcaga aatacctgtg gtcgtttctt tataatcaat tgaaactgta aaagcagtct
    10501 tatgattatc tgtattgttt tcaaccatag gtgaaagcat taattgatta gctaaacttt
    10561 cgctcatagg catacaaatt aatcctttgg cataagtagc cataaaatta acattttctg
    10621 ttgtagctgc ttgtgcagaa caaattaagt ctccttcatt ttctctatcc ttgtcgtcta
    10681 taacaagaac aagtcgtccc ttctgcaatg cttctaatgc ttcttgtatt tttcgatatt
    10741 ccattgactg attatccttt ctgctaaaat ccattttgat ataatagttc cttagatatt
    10801 tctgattttg gagagttatc catcagtttt tgcacatatt tacctaagat atcattttca
    10861 agatttactg tactcccgac ttgtttactc ttaagaatgg tttgttccaa ggtatgaggg
    10921 ataacagata ctgaaaagtt tactttggag actttagcga cagtcagact aatgccgtca
    10981 attgtaatag atcctttttc aactattaaa tctaaaattt ctttttgtgt gttgatttga
    11041 taccatacag cattatcatc tttttttatt gacgagattt ttcctgtacc atcaatgtgt
    11101 cctgtaacga cgtgaccccc aagtcgaccg ttgatagata aggctctttc tagattcacc
    11161 tcacttccat gttttaatag agtaagagct gttcgactcc atgtttcatt cattacatca
    11221 actgtaaagg attgatgatt gaaatgagta actgtaagac agataccatt tactgctata
    11281 ctatcgccta aatggatatc cgttaatatt tttgaggctt taattgatag tttacaatta
    11341 cgagagtctt tctgtattct ttcaactttt ccgatttctt caattattcc tgtgaacatg
    11401 gataaatcac ttcactttct atgagatagt catttcctat ttgagaaaaa gcataaggtt
    11461 tcaatctaat agcgtcattt ggcaaagaaa tgccttcacc tccgacagga aacttggcac
    11521 tgcctccaaa aatttttggt gcaatatata ttttcagctc atcaacaatt tgttgttcca
    11581 aagcactcca attcattaga ctgccccctt ctagaactag gctatcaatc tgcatgtttc
    11641 ctagatgttg cattaaactc gataagtcta tatgattgcc ttttttcttt atggaaagta
    11701 tttcacagcc atgattttga tatagcttca ttttattttt gtcttcagag gaagtggcaa
    11761 tgtaagtttt aatatcattt gctgttttta cgattttaga ggtaagagga gttcgtaaat
    11821 gtgtatcgca tatgatacgg ataggatttt tcccttcctc caatctacat gtcagcaaag
    11881 gatcgtcttg aataacagta ttgactccca ccataattgc actaacatgg tgtcgtaact
    11941 gatgcacatg ctttcttgct tcttcttcag taatccattt ggattgattt gttttagtgg
    12001 ctatttttcc atccattgac attgcatatt tcataaaaac atagggtaca tgctgggtaa
    12061 tatactttct aaaacttttt attaagttaa gacactcatt ttctaaaatt ccaacagtaa
    12121 cttgaagatt attttcctca agtatcttta ctccttttcc agatacaata ggattacagt
    12181 ctaggcttcc aatgactact cttgtaatac cactatcgat tatagcatct atacagggag
    12241 gtgttttccc gaagtgacaa cagggttcaa gtgttacata aagcgtcgct ccgacagggg
    12301 attctctaca gtttttaaga gcatttctct cagcatgtgg gccaccaaaa aactcatgat
    12361 aaccttgtcc gataatgtga ttatctttta caataactgc gccgaccata ggattgggat
    12421 tgacgtaacc agcccctttt tgtgccagtt ttattgctaa tttcatatat tttgaatcgc
    12481 tcatctcact acctccaaaa aaatatgcct tgaatagggg actactcaag gcatacaaaa
    12541 gaaaacttat gcgattaaca aaaatgctct gaaatgacaa gtaatcattt cagagcacgc
    12601 aaaaagcaca aatatacttt tatcttcttt catccagact atactgtcgg ctttggaatt
    12661 tcaccaaatc atgcctttcg gctcgtgggc tataccaccg gtagggaatt tcaccctgcc
    12721 ctgaagatag ttattcaatt acagatgatt atagtactta attttgaata tgtcaacaga
    12781 taaataccga ttgtttttga tatactgtat ttgtgataat cgattctcgc tcctcggata
    12841 aagaaaatat gatatactag ataaacgaaa taagagagaa ggaatactat gtacgcatat
    12901 ttaaaaggaa tcattaccaa aattactgcc aaatacattg ttcttgaaac caatggtatt
    12961 ggttatatcc tgcatgtggc caatccttat gcctattcag gtcaggttaa tcaggaggct
    13021 cagatttatg tgcatcaggt tgtgcgtgag gacgcccatt tgctttatgg atttcgctca
    13081 gaggatgaga aaaagctctt tcttagtcta atttcggtct ctgggattgg tcctgtatca
    13141 gctcttgcta ttatcgctgc tgatgacaat gctggcttgg ttcaagccat tgaaaccaag
    13201 aacatcacct acttgaccaa gttccctaaa attggcaaga aaacagccca gcagatggtg
    13261 ctggacttgg aaggcaaggt agtagttgca ggagatgacc ttcctgccaa ggtcgcagtg
    13321 caagcaagtg ctgaaaacca agaattggaa gaagctatgg aagccatgtt ggctctgggc
    13381 tacaaggcaa cagagctcaa gaaaatcaag aaattctttg aaggaacgac agatacagct
    13441 gagaactata tcaagtcggc ccttaaaatg ttggtcaaat aggagcagag aatgacaaaa
    13501 cgttgttcgt gggtcaagat gaccaaccca ctctacatcg cctatcatga tgaggagtgg
    13561 gcccagcccc tccatgatga ccaagcgttg tttgagttgt tgtgtatgga aacctatcag
    13621 gcaggcctgt cttgggaaac ggtactcaac aaacgccaag ctttccgaga agcctttcat
    13681 agctatcaaa ttcactcagt cgcagagatg actgacactg aattggaagc catgctggag
    13741 aatccagcta tcattcgaaa tagagccaag atttttgcta cacgcgctaa cgctcaagcc
    13801 tttctacagt tacaggcaga gtacggctct tttgatgcct atctttggtc ttttgttgag
    13861 gggaaaactg tcgttaacga tgttcctgat tatcgccaag ccccagctaa aacaccctta
    13921 tctgagaaat tagccaaaga tctcaaaaaa cgaggcttca agttcacagg cccagtcgcc
    13981 gtattgtctt ttctacaggc tgcagggcta gttgatgacc acgagaatga ttgtgagtgg
    14041 aaaggtctta aatgatgtct aacaaaaata agggaattct gatttttgcg attctctata
    14101 cagtcctctt tgtgtttgat ggcgttaaat tgctggcttc tttaatgcca tctgccattg
    14161 caaattatct tgtttatgta gttttagctc tatatggctc cttcttattc aaggatagat
    14221 tgatccaaca atggaagggg attagaaaga ctaaaagaaa attcttcttt ggcgtcttaa
    14281 caggatggct ctttctcatt ctgatgactg ttgtctttga atttgtatca gagatgttga
    14341 agcagtttgt ggggctagtc ggacaaggtc taaatcagtc taatattcaa agcacttttc
    14401 aagagcaacc actactgata gctgtttttg cttgtgtcat tggacctctg gtagaagaat
    14461 tatttttccg tcaggtctta ttgcattact tgcaggaacg gttgccaggt ttactaagca
    14521 ttattctggt aggacttgtt tttgctctga ctcatatgca cagtttggct ctatcagagt
    14581 ggattggtgc agttggttac ttaggtggag gccttgcctt ttctattatt tatgtgaaag
    14641 aaaaagagaa tatctactat cccctacttg ttcacatgtt aagcaacagc ctctccttaa
    14701 tcattttagc tatcagtata gtaaaatgaa ataagaacag gacaaatcga tcaggacagt
    14761 caaatcgatt tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatttgct
    14821 gtaatatgtg atggaaatgc cagtaatgat accgagaaaa aagctgagaa acttttccca
    14881 gctttatttg ttatagtcaa agcgaatgac ttgttcctgt gcatctacat gagcatggac
    14941 cccaaagggt acaattgctc ttggagttgc gtggccggca ttcagattat agacaatcgg
    15001 gatattgctg tcaatgatat ccaatagtgc ctctttatag tcgtcatgga aggtttcatc
    15061 cataggtttt ccgaccaaga gtccattgat gaccgcgaat atgccagtgt cctttaaagt
    15121 tagcaacatc tttttgaagt cttctggctt aggcttttct tcgcttgttt cgagcaagag
    15181 gattttccct tcccagtctg acaagtcagg gaaaagtttg tatttttggc agagttccgt
    15241 gctatctgcg tatcgagagt tgtcaaagat atcgtagagg gattcgaggc aaccaccgag
    15301 gattttcccc tcgaactgag cacttccttg caacaagtca aaacctgtat ttgtatgact
    15361 gacacgaggt gttcccaggg ccgtgggact aaaatcagtt cgttcctcat accaaacgtc
    15421 actagggcgg atttctgaaa ttcttcccgt cttaatcaat tctttaaagt agtgaaggct
    15481 ataggctagc atttctttgt ctaattcaca aatgtctgct aaaaaggatt gaccataaaa
    15541 agtcttgatt cctaatttat gcaacatgag gtggttcatg gttgtatccg agaagccaag
    15601 aaaaattttt tgtttgataa ccttttggag ttggtcattt tcaaaaagat aaggtagcaa
    15661 gcgataggta tcgtctccac cgatggcaca taggatcatg tcgatgctat catcagaaaa
    15721 ggcatgaatc aaatcctctg cacgagcttc aggatggtcc ttgataaagt ctaatccttt
    15781 taacgaatgg ggcaaaaaga tgggattgag tcccagatcc ttgagacgtt ggatacccaa
    15841 gtccacttcg tgtttgacaa aatcctctcc gataatgcca ctagataaac taacaatacc
    15901 aatagtagaa accatatctc atcctcctag aaatagattg agcctatttt atcacaaaat
    15961 ataagagaaa gctatgtggg atttcagaag aatactttta atactcttcg aaaatctctt
    16021 caaaccacgt cagttttatc tgcaacctca aagctgtgct ttgagcaacc tgcagctagc
    16081 ttcctagttt gctctttgat tttcattgaa tataactcaa aaaagtaagt gaaaaagcaa
    16141 ccgcacctgc agttgctttt atcgttttct tattcttgat agcgtgttgg tcctgcactt
    16201 gcactacgga tattcaagcg tttcttgaga tagaagcgaa gggctaggag ggctgctcca
    16261 ataatagcta gtggcaatgg atccagtact gggttaaggc tagctggtag gaagcttgtt
    16321 gcaaagaaga caagcaacca aaggaacata gaagctagga taactagtac agatttccag
    16381 aaaggtggac gttgactgcg atccatatct ggtccatagt attggtaaac aaagtagtac
    16441 atcaagtaga aggcaaatcc accaaccagt ccaactaata gaagagtaat caatccatag
    16501 ccgaaagctt ggtctgccgc aaagaaggtt gtgagggcgc tgacaagggc aaagaggcta
    16561 gtgatgaaaa gagctgagtc cataatcatc agttttgggt catcattttc ttttggatgc
    16621 tctttttcgt actgctcttt gacagtgaag ctatgagccc aatgagttgg tgcgccgtat
    16681 agggaacggg cagttgtacc tttagattgc tcctcaagga tttggggaat gacttcctca
    16741 aaaatagtct ggatttcagc gtctgttttc ccatctttga tgaattgttg ggtagcaatg
    16801 tggacaaact cttggttttt cttagttaat ttttgtagat caatttgaga cataggaact
    16861 cctcttagaa ccatttttta tggatgagat agagagtgag cgagacactc atagcaaagg
    16921 cgataaagac gattaaccag aaggcatttg gctctccgtt tagggggatt tcattatcct
    16981 taaagttcat cccgtaggca gaaaagacca tggttgggat ggacatgacg atggtcacaa
    17041 gggccaaggt tttcatgatg ttgttctggt tgttagaaat gatagaggca aaggtctctg
    17101 tcatagaatg caagacgttt ccataaatat ctgccatctc gatggcctgt tgggtttcaa
    17161 tcagggtgtc ttcaagcagg tcttcgtcct caaggtattt cttgatattg ctggttgaac
    17221 tggtcaattt cttaatcacg cgctcatttg ttttgaggga ggccttgaaa tagacgatag
    17281 ttttttccaa ttccatgagc tcaatcaatt cttcattacg agttgattga tgcagttgac
    17341 tttcgatttg ttcactcttg cggtcgattg aacgaagggc tgttaggtaa agctctgcat
    17401 tgcgataaag aatttgaaag ataaaacgtg aacgcatgaa ggtatagaaa ttacgcaatc
    17461 gacggttgat aaagacatca aggacaggta gtggttccaa acacgtagtg ataatggttt
    17521 cctcagtgat gataatacca agcgggatgg ttacgtagta ggtgcggtta tttctttcct
    17581 ccgtgaccgg cacgtctacg ataatcaggg tatactcgtc ttcaatggta atacgagaca
    17641 tttcttccgc atcgagcggt gctcgaaggt cggcaatatc aatatcgaag gtgttggcga
    17701 tttcgagtga ttcattttga gtcggattga cgagattgat ccaagtaccc ggttcaagcg
    17761 tatcgatctc tttaaattca gttgttgtag agagaaaaac ttgtttcata tcccttatcc
    17821 tttctcattt ttcagatttt ttcacactgt ac
//
LOCUS       DAVDHC010000043        15459 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVDHC010000043 DAVDHC010000000
VERSION     DAVDHC010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15459
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.043"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            215..1978
                     /gene="aspS"
                     /locus_tag="VUR43_001945"
     CDS             215..1978
                     /gene="aspS"
                     /locus_tag="VUR43_001945"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET5413586.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITESLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVRGVDFKVFSEAPAVKAIVVTGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALVLEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            1956..2897
                     /locus_tag="VUR43_001946"
     CDS             1956..2897
                     /locus_tag="VUR43_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET5413587.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(3018..3098)
                     /locus_tag="VUR43_001947"
                     /pseudo
     CDS             complement(3018..3098)
                     /locus_tag="VUR43_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(3234..4220)
                     /locus_tag="VUR43_001948"
     CDS             complement(3234..4220)
                     /locus_tag="VUR43_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5413588.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(4230..5030)
                     /locus_tag="VUR43_001949"
     CDS             complement(4230..5030)
                     /locus_tag="VUR43_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET5413589.1"
                     /translation="MLPYPFSYFSSIWGVRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASFLLYITKRSRLFSFNTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(5283..6125)
                     /locus_tag="VUR43_001950"
     CDS             complement(5283..6125)
                     /locus_tag="VUR43_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5413590.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(6127..7419)
                     /locus_tag="VUR43_001951"
     CDS             complement(6127..7419)
                     /locus_tag="VUR43_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5413591.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(7530..8801)
                     /locus_tag="VUR43_001952"
     CDS             complement(7530..8801)
                     /locus_tag="VUR43_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5413592.1"
                     /translation="MSSKFMKSAAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            9351..10868
                     /gene="malQ"
                     /locus_tag="VUR43_001953"
     CDS             9351..10868
                     /gene="malQ"
                     /locus_tag="VUR43_001953"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET5413593.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            10894..13152
                     /gene="glgP"
                     /locus_tag="VUR43_001954"
     CDS             10894..13152
                     /gene="glgP"
                     /locus_tag="VUR43_001954"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET5413594.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAVVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERFYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(14196..14768)
                     /locus_tag="VUR43_001955"
     CDS             complement(14196..14768)
                     /locus_tag="VUR43_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413595.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAVWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
BASE COUNT         4618 a         2880 c         3287 g         4674 t
ORIGIN      
        1 ggttttgagg ttgtagatga aactgacgaa gtcagtaacc atacatacgg taaggcgacg
       61 ctgacgtggt ttgaagagat tttcgaagag tattagcgct aatttttagg gctttcacct
      121 gacttttaaa gactggcaaa cttttctgat gattttcatg aagagcctgc gcttttatgg
      181 taaaatagta acagaataaa agaggagaga aataatgaaa cgtagtatgt atgctggtcg
      241 tgttcgtgag gaacacatcg gacaagaaat aaccttgaaa ggatgggttg gccgtcgtcg
      301 tgaccttggt ggtttgatct ttatcgatct tcgtgaccgt gaaggaatca tgcagttggt
      361 tatcaaccct gaaaaagtat ctgcagaggt tatggcaaca gctgaaagcc ttcgtagcga
      421 atttgttatt gaggtgactg gtcaggtcgc tgcgcgtgag caagccaatg ataagttgcc
      481 aactggtgcg gttgagttaa acgtgacagc tcttattgtg cttaacacag ctaagacaac
      541 accatttgag attaaggatg gcattgaggc aaatgacgat acacgtttgc gttaccgtta
      601 ccttgacctt cgtcgtccag aaatgttgga aaatcttaaa cttcgtgcca aggtgaccca
      661 ctctatccgc aactacttgg atgagttgga gtttatcgac gtggagacac cattcctttc
      721 taagtcaacg cctgaagggg cgcgtgatta tttagtgccg tctcgtgtta ataaggggca
      781 tttttacgct cttcctcaaa gtccacaaat cacgaaacag ctcttgatga atgctggttt
      841 tgaccgttac taccaaatcg ttaaatgttt ccgtgacgag gacttgcgtg gagaccgcca
      901 gcctgaattt actcaggtcg acttggaaac gtccttcctt actgagcaag aaatccaaga
      961 tattacagaa agcttgatcg cgcgcgtgat gaaggaaaca aaaggcatcg aagtaacgct
     1021 accattccct cgtatgaaat acgatgatgc tatggctctt tacggttctg acaagccaga
     1081 tactcgtttt gacatgttgc ttcaggactt gacagaagtg gtccgaggtg tagactttaa
     1141 agtcttttca gaagcacctg ctgtaaaagc gattgtggtc acaggagctg cggacaacta
     1201 ttcacgtaaa gacatcgaca agatgacgga agtagccaaa cagtatggtg ccaaaggtct
     1261 tgcttgggtc aaggtggttg atggagaatt aaacggacca gttgccaagt tcttgactgg
     1321 tatccaagaa gaattgacaa cagcgcttgt tcttgaagat aaggacttgg ttctctttgt
     1381 ggcggatacg cttgaagtgg ctaatgcaac actgggtgcc cttcgtggac gtattgctaa
     1441 agagcttggc ttgattgata atgataagtt caacttcctt tgggtggttg actggccgat
     1501 gtttgaatgg tctgaagaag aaggccgcta catgagcgcc caccatcctt tcacacttcc
     1561 acaggaagag actgctcatg aattagaagg tgatttggct aaggttcgtg ccattgctta
     1621 cgatatcgtc ttgaacggtt atgagcttgg tggtggtagc cttcgtatca accaaaaaga
     1681 ccttcaagaa cgcatgttca aggctcttgg tttctcaact gaagaagcca atgaccagtt
     1741 tggtttcctt cttgaagcca tggactatgg tttcccacca cacggtggtt tggctatcgg
     1801 gcttgaccgt tttgtcatgt tgcttgctgg agaagaaaat atccgtgaag tcattgcctt
     1861 tcctaagaac aacaaggcaa ctgacccaat gacacaagct ccatcaacag tcgctctcaa
     1921 acaactagag gaactcagct tacaagtaga agaagatgaa acaaacaaaa cgaattaagc
     1981 ggtggcgcta ttatctgcgc cgctttgctt atcagataaa aattttacgt gtcttacaaa
     2041 gtatctctcg agaaaagtat gatgagaaga tttcggcctc tctggtctat ggttttttat
     2101 cagcagtagc agttaatttc tttttccaac cagggcatgt gtattcgagt ggtgcaacag
     2161 gtctggcaca gattatctct gccttgagta atcactggtt tggttttcat attccgattt
     2221 cgctaagctt ctacgccatt aacttccctt tgatggtctt agcttggtat cagattggcc
     2281 ataagttcac cgtctttacc tttatcacgg tatctatgag ttccttcttt atccagtttg
     2341 tccctgtggc aaccttgaca gaggatccca ttatcaattc cctttttggg ggtgttgtta
     2401 tgggtttggg gattggtttt gctcttcgaa acaatatctc cagtggtggg acggatatcg
     2461 tcagcctgac tattcgtaag aaaacgggta agaatgtcgg tagtatttct ttcttggtaa
     2521 atggaactat catgctgata gcaggtttga cctttggttg gaaatacgct ctttattcta
     2581 tgattaccat ctttgtctct agccgtgtga cagacgcagt ctttactaag caaaagcgta
     2641 tgcaggccat gattgtgaca aatcatccag agaaggtaat tgaaaaaatc cataaaaaat
     2701 tgcaccgcgg agcaaccatg atccacgatg cagaaggaac ctataatcac gagagaaagg
     2761 cagttttaat cactgtcatt acacgtgcag agtttaatga atttaaacag attatgacac
     2821 aagtggatcc aagctccttt gtctctgtct cggaaaatgt tcatattcta ggaagatttg
     2881 ttgagataga taattagtga ttaatactct tcgaaaatct cttcaaacca cgtcagcttc
     2941 accttgccgt aggtatggtt actgacttcg tcagtttcat ctacaacctc aaaaccatgt
     3001 tttgagctga cttcgtcagt ttcatctaca acctcaaaac agtgttttga gcaacctgcg
     3061 gctagcttcc tagtttgcac tttgattttc attgagtata aaaagatctt gggaaaagac
     3121 tcaatttcag tagaaaagga agtaaatctt cccacaataa aacgcatagt atcaagtttt
     3181 ttcaatacct gatagtatgc gtttttgctt ttaacgactt tttgcccagt ctcttatttt
     3241 tcgataattt tgtgggcgat caattgacgg taacaaattt gtttattgtt tttattatca
     3301 ttaataatct ggagaatagt ttcaagggaa acacgaccaa gctctaaact attgatatcg
     3361 acataggctg ccaagttgag cttgggatta accgagtcaa agctgagaac agggacatcc
     3421 agctggtgtt tggcaatata gttacaaaca ccttcagcta gaaggctatc ggttgtgatg
     3481 atagcatcaa tttgtggatc gtgcttgaat aatcgcttgc taaatttata gcccttttct
     3541 tccagaaact cgtcggcaaa gtagatgcga ttgttgtcag tggtaagttt gtaatgttta
     3601 agcgcctgtt catagcctgt taaacggtct ttggtcacga agagcttttt acttcctccg
     3661 ataaaggcaa tgcgtttgca gccttttttg atgaaatatt cagtcgcatc aaaaccagct
     3721 tgaacattgt cgttgtcgac aagtgggatg aaaggagata gagatttacc taagataagg
     3781 aaggggaact gttcttctgc gacgagtttt acgagagggt cttcttcttg ggcatagaga
     3841 aaaattagcc catctacacg cttgccgtag accatttgtg aaatagcgtt gagacgctcc
     3901 ttctcatctt tccctgttgc tatctgaatg gcatagtggt tttcagatgc gacttgagag
     3961 atgccacgta gaaccgatgg aaagaaagga ttctggtaga aggcgtctga gtcatcagga
     4021 agaactaatc cgataacctg agtatagctg cttaccaagc tacgagcgtt gaggtttggg
     4081 tggtagttga gttccttcat agctttgcga acacgttttt ttgtttcgtc gctaatggtt
     4141 gatttatttt gaataacacg ggttacggtt gaaggcgaaa caccagcagc cttggccacg
     4201 tctttaatcg taacgggcat aaaaatctcc tatttatggt aatttggatc acggaaatgt
     4261 gttttataaa agatagtgac cagatacaga acaaaaagaa tattttgtac agtaatcagg
     4321 gttgtcatat tttggccaaa taatcccaaa ataagtgtaa tcagagtcgg caatcctaaa
     4381 cagttcaaga taaaatggta gcactcttta aaggtattaa atgaaaagag gcgtgatctt
     4441 ttggtgatat aaaggagaaa gctagctcca agagagacga taaagaaatt caaaccaaag
     4501 aggaagctcg caccgagaac taggaagagg ctgatataga cacgattttg ttggtaccag
     4561 tctttagaaa ttgcttgggt caagctgtct ttgcttttga aactctcagt ctgaatggct
     4621 cggtaagaga tgcgggtcag ttccttgctt tccttgctga tgactagctc atttgtatcg
     4681 aaatgcagtt gcaagtcctt aggtaattcc ttgatttgac ttggaccaat cacaacagaa
     4741 ggggcttgac tagctgttcc agtataagtt aatgtgccat cgacaattgt agcatgttca
     4801 gagagatcct ggacaacctt atctgtcaga ggttcataga cattatcgat aaaagtttct
     4861 agcggatagg tctcctggga gctgttttgg atagcaatgg gtaccataga caagctgata
     4921 aggaagatac tggtaaagag aagttgaaac cagttgagct cgaaacgttt ggacaggggc
     4981 ttacgaaccc cccaaatact tgaaaaatag gaaaatggat atggaagcat aggtatcttt
     5041 ctaaaaggtg ttttctatat gagtattatt atatagagaa atgcgcttta tttcaagtct
     5101 aggagaaaaa ttgcttgcta caaggatatt atttacagtg acaattgcta ataatcaatg
     5161 aaaatcaaag tgcaaactag ccacaggttg ctcaaagcac aactttgagg ttggagataa
     5221 agctgacgtg gtttgaagag attttcgaag agtataaaat gaaaaagggt ggcggggata
     5281 aattatccct tgtcgccacc acttgtaagt cctgaaacaa agttcttttg taggaagaag
     5341 aagagaatac agattggaag ggcgatgagg atagcacctg ctgagaagta ggcaatcttc
     5401 aagtttttcg cattgttaac gaaggtttgg agacctacgg caacagtaaa gtattctttc
     5461 tcacgaagca agaaactaga gaggatatag tccccgaaag gtcccatgaa ggcccagaga
     5521 gcttgtacgg caaccattgg gcgaacaagt ggtagaacaa tttgccagaa gcggcggaag
     5581 tgtcctgcac cgtctagttt tgcagattcg tctaaagaca ttggcactgt atcgaagtag
     5641 cctttcatga gccaagcatt catcgggata ccaccaccaa cgtagaggaa gatgaggaac
     5701 cagttgtggt taagggcgtt caacataagc gccataacga agaaggctgt caaagcggcc
     5761 atagttggca ccatttggat gatcaagaag aagaccaaac tttgtttacg agccaagaag
     5821 ttgtaacggc tgtaagcata accagcaagt acgatgatac ttgtttgaac agccatggta
     5881 attaaggcga taatcaaagt gttgaggtac caagtaccgt acaaggtttc agtgaagagg
     5941 cctttaaagt tatcaaaatt gaggtcgata ttagtatcta gtttaaaggc tgagacgtta
     6001 cctgctttaa aggctgacat gatggtaatc aacagtggat agataattac aattgataga
     6061 ccaatcaggt aaaggtaagt aaggctttga gtcagtctac gtttgagttt aattgagtta
     6121 ttcatcttag acgtcctcca tatcaaatgc gtgtagtttc ttgaatgcga tcatagagat
     6181 tgagatgaca atgatagaga taatcaaggt aacagctgcc gccattgagt attgaggaga
     6241 tgtacctgtt gtcaaacggt agatccatga gatcaagata tcggttgaac cagctccacc
     6301 tccgacacta ccaggtcctc caccattgaa gaggtacatg atagagaagt tgttaaagtt
     6361 gaaggtgtat tggctaatca aagtaggtgc cgcaacagcc aaaatcattg ggaaagtgat
     6421 gttgcggaat ttttgccaag cgttggcacc gtcaatataa gctgcttcgt aaaggtcgtt
     6481 aggaatagat tgcaagatac ccaaggtcag aacgtagatg tatgggaatc cgagccaacc
     6541 ttgcatcata atcaaggcaa tcttagtcca agttgggtct gttttccaag gaataagagc
     6601 tccatcaagg aaaggaagga atttagccaa gattggcaat acttgagtgt tgatagcacc
     6661 gacactatcg ttaaacatgt ttgagaatgt caagatagtg atgaaggctg ggacagccca
     6721 aggaagaagg aaaataacac caaagatacg ttttcctttg ataaatggtt ggttggcaat
     6781 gatagctgtg aagataccaa ttacgatttg taaagtagaa gctgccaaag cccaaatgat
     6841 agtccaagaa agaacagaac caaaggcaga acggaaggta ctcaagctcc aaatgtttgt
     6901 aaagttggtc aaaccaaccc agtccaacaa cttgtttggt ggcaagtgtt ggaagtcgta
     6961 gttggtaaag gcgatcatca aggttacgat aactgggaag ataatcgcga aggtcatggc
     7021 aacataagat ggaatgatca agaggtaagg gaagccattt tcataaatcc ctttgatcat
     7081 gtctttgagt gtgcgtggaa ctggaattcc attattaatg cgttttgcaa tcgtatgtgc
     7141 atctttgata tttgagaaat aaaagagtac ataaacgatt acaaagatta gatggaaggc
     7201 accacgaatc agcataaaga gggaattatc acgacctggt ttgtcaccaa gagtgatgag
     7261 gttgctcaat tcaggggttg caagtgctag gaagtaaagg acaaatacga tggttacacc
     7321 aaggaagata aaacctttgg ctttttgttt attgtaaatc tgtcctaacc caggaatgat
     7381 agacagcagg gctgctttac taggttgttg cttttccata ttaactcctt tcataggata
     7441 ctactttttt ataagaaagc taaattattt gtgtctctat tgataaattc aaagggggat
     7501 ttgatttcca ccccccttga acaaattttt tattcaccaa atttttgttt gattgtttct
     7561 ttgatcaatg ttacagcatc gttagcagct gttttagcat ctttttgacc acttacagca
     7621 tcaaagagca tatttttcgc tggatcccaa actgcagaca tttgagagat gtttggcagt
     7681 ggttgagtgt tcttgaactg tttgataaca gctgttgtca actcatcgtt tttaccttca
     7741 gcgtatgaac gagcctcagt attagctggg atttcgttag tcttatcata taatactttt
     7801 tgttgttcag ttgcaacaag gaagtctaca aatttttgag aagcttcaag gttcttaacg
     7861 gcttgaggaa tgacccaagc tttaccacca ccgaatgcag catattcttt tccatttgga
     7921 agagttggga tagttgcaac tccgtagttt actttagcat ctttaaaggc ttgagctttc
     7981 caaggtccgt cgatgatagc agctgtttta ccttcttgga attgagtttg gattaagttt
     8041 ccagcacctt ctgtatcttg cataccttta ggccattttt cgtaccaaga tttagcgtag
     8101 ttgataccta cgatagaacc gtcgtttgca agaccgatgt ctttagcgtc tttaccgttt
     8161 tggccaaaga cgtaagcacc gttaccggca agaagtccat atgtatagta gaagtttgtc
     8221 cagtcagcta ggaaggcagt agttttacca tcttcaccag cgaatgcgta tttgctatct
     8281 ttagcaaggt tttccaagtc agcaaatgtt tttggagcat ctttcaccaa gtctttgttg
     8341 tagtacataa caagtgactc gataacggca ggagcaccgt aaactttacc attagcagct
     8401 gttacaagag atttagttgt gtcgtctgtt ttagcaccat cgctcaattt cacttctgaa
     8461 agttgtccgt cagaaccaag gctacctaca cggtcgtatg gagccatcat aacatcaggg
     8521 acattaccag attggttgtc aagagaaagt ttatcaagac ctcctagagc atcaccagtt
     8581 ttaagagtga cttttactcc agcttctttt tcataagctt tagcaacctc ttcaatatag
     8641 ctcttatatc cctcgtctac atatacagtg agttctttga cttcagatga accagaatca
     8701 gcaggcttat cagcagtttt gcttccgcaa gctaccaaaa gcaagctagc aagtgtagca
     8761 gttccaagca ccgcagcgct cttcataaat ttagatgaca tagtgtattc ctcctaaaga
     8821 atagcaagtt ttattgataa ggaaacgcaa acgttttcct ttatgagctt agtatagcac
     8881 aaatagaaaa cggttgcaag tattttttgt aaaaatttta aaaaattttt aagcttgatt
     8941 tgatagcata attttgcatt ttaatagaag aaaagtatga aatagataag aatacagtat
     9001 ttttaataaa aatatatgaa atctgtctaa agagggaaat caggaggggc taccttccta
     9061 tttctaatct atatctattt tctatagacg tttgtgcttt gttgcatata aattcaagct
     9121 ccctaaggag gttttgtact ttgtatactg tctcgtgaga gtcaaacttt aggattagat
     9181 agttttaagt tatctttgct aaaatgagtt agtctcctta aaaataatca aaaaagtttt
     9241 ttaaaaacgc ttgcaattat gcttgaaaag gagtatactt ataagtaacg caaacgtttg
     9301 cgtctgaaaa atacgcaacg ttccattatt ttaacacacg aggtgctatt atgaaaaaac
     9361 gtcaaagtgg tgtgttgatg cacatctctt ctcttccagg agcttacgga atcggatcat
     9421 ttggtcaaag tgcttacgac ttcgttgatt tcttggtccg tacaaaacaa cgttactggc
     9481 aaatccttcc attaggagca actagttacg gggattctcc ttaccaatct ttctcagcct
     9541 tcgcaggaaa cactcatttt atcgatttag atatcttggt ggagcaaggt ttgttggaag
     9601 caagtgacct tgaaggagtt gactttggta gcgatgcgtc tgaagttgac tatgctaaaa
     9661 tctactatgc acgtcgtcct cttttagaaa aagcggtgaa acgtttcttt gaagtcggag
     9721 atgttaaaga ttttgagaaa tttgctcaag acaaccaatc atggcttgag ctctttgctg
     9781 agtatatggc tatcaaagag tattttgaca atcttgcttg gactgaatgg ccagatgcag
     9841 atgctcgtgc tcgtaaagct tcagcacttg aaagctatcg tgagcaattg gcagacaagt
     9901 tggtttacca ccgtgtgact caatacttct tcttccaaca atggttgaaa ttgaaagctt
     9961 acgctaacga caaccacatc gaaatcgttg gggacatgcc aatctacgta gcggaagatt
    10021 caagtgatat gtgggcaaat ccacatctct tcaaaacaga tgtcaatggt aaggctactt
    10081 gtatcgcagg atgcccacca gatgagtttt ctgtaactgg tcagctttgg ggtaatccaa
    10141 tctatgactg ggaagcaatg gacaaagacg gctacaaatg gtggattgaa cgcttgcgtg
    10201 aaagcttcaa aatctacgat atcgttcgta tcgaccactt ccgtggcttc gaatcttact
    10261 gggaaatccc tgctggttcc gatacagcag cacctggtga gtgggtgaaa ggtccaggtt
    10321 acaagctttt tgcagccgtt aaggaagaac ttggtgagct aaacatcatc gcagaagacc
    10381 ttggcttcat gacagatgaa gtgatcgaat tgcgtgaacg tactggcttc ccaggaatga
    10441 agattcttca atttgccttc aacccagaag acgaaagcat tgatagccca cacttggcac
    10501 ctgctaactc agttatgtac acaggaacac acgataacaa tacggttctt ggttggtacc
    10561 gtaatgagat tgatgatgcg actcgtgagt acatggctcg ttacacgaac cgtaaagaat
    10621 acgaaacagt ggtacacgct atgcttcgta cagtattttc atcagttagc tttatggcaa
    10681 ttgcaactat gcaagattta ctagaattgg atgaggcagc tcgtatgaac ttcccatcta
    10741 cccttggtgg aaactggtct tggcgtatga ctgaagatca attgacacca gctgtcgagg
    10801 aaggtttgct tgacttgaca acaatttatc gccgaattaa tgaaaatttg gtagatttaa
    10861 agaaataaga caataatcag gagacaacta aacatgttat cactacaaga atttgtacaa
    10921 aatcgttaca ataaaaccat tgcagaatgt agcaatgaag agctttacct tgctcttctt
    10981 aactacagca agcttgcaag cagccaaaaa ccagtcaaca ctggtaagaa aaaagtttac
    11041 tacatctcag ctgagttctt gattggtaaa ctcttgtcaa acaacttgat taaccttggt
    11101 ctttacgacg atgttaaaaa agaacttgca gctgcaggta aagacttgat cgaagttgaa
    11161 gaagttgaat tggaaccatc tcttggtaat ggtggtttgg gacgtttggc tgcctgcttt
    11221 atcgactcaa ttgctactct tggtttgaat ggtgacggtg ttggtcttaa ctaccacttt
    11281 ggtcttttcc aacaagttct taaaaacaac caacaagaaa caattccaaa tgcatggttg
    11341 acagagcaaa actggttggt tcgctcaagc cgtagctacc aagtaccatt tgcagacttt
    11401 actttgacat caactcttta cgatattgat gttactggtt atgaaacagc gactaaaaac
    11461 cgcttgcgtt tgtttgactt ggattcagtt gattcttcta ttattaaaga tggtatcaac
    11521 tttgacaaga cagatatcgc tcgcaactta actctcttcc tttacccaga tgatagtgac
    11581 cgtcaaggtg aattgctccg tatcttccaa caatacttca tggtttcaaa cggtgcgcaa
    11641 ttgatcatcg acgaagcaat cgaaaaagga agcaacttgc atgaccttgc tgactacgca
    11701 gttgtccaaa tcaacgatac tcacccatca atggtgattc ctgaattgat tcgtcttttg
    11761 actgcacgtg gtatcgatct tgacgaagca atctcaattg ttcgtagcat gactgcctac
    11821 actaaccaca caatccttgc tgaagcgctt gaaaaatggc ctcttgaatt cttgcaagaa
    11881 gtggttcctc acttggtacc aatcatcgaa gaattggacc gtcgtgtgaa ggcagagtac
    11941 aaagatccag ctgttcaaat catcgatgag agcggacgtg ttcacatggc tcacatggat
    12001 atccactacg gatacagtgt taacggggtt gcagcactcc atactgaaat cttgaaaaat
    12061 tctgagttga aagccttcta cgacctttac ccagaaaagt tcaacaacaa aacaaacggt
    12121 atcactttcc gtcgttggct tatgcatgct aacccaagat tgtctcacta cttggatgag
    12181 attcttggag atggttggca ccatgaagca gatgagcttg aaaaactttt gtcttatgaa
    12241 gacaaagcag ttgtcaaaga aaaattggaa agcatcaagg ctcacaacaa acgtaaattg
    12301 gctcgtcact tgaaagaaca ccaaggtgtg gaaatcaatc caaattctat ctttgatatc
    12361 caaatcaaac gtcttcacga gtacaaacgc caacaaatga acgctttgta cgtgatccac
    12421 aaataccttg acatcaaagc tggtaacatc cctgctcgtc caatcacaat cttctttggt
    12481 ggtaaagcag ctccagccta cacaatcgct caagacatta tccatttaat cctttgcatg
    12541 tcagaagtta ttgctaacga tccagcagta gctccacact tgcaagtagt tatggttgaa
    12601 aactacaacg ttactgcagc aagtttcctt atcccagcat gtgatatctc agaacaaatc
    12661 tcacttgctt ctaaagaagc ttcaggtact ggtaacatga aattcatgtt gaacggagct
    12721 ttgacacttg gtactatgga cggtgctaac gtggaaatcg ctgagttggt tggagaagaa
    12781 aacatctaca tcttcggtga agattcagaa actgttatcg acctttacgc aaaagcagct
    12841 tacaaatcaa gcgaattcta cgctcgtgaa gctatcaaac cattggttga cttcatcgtt
    12901 agtgatgcag ttcttgcagc tggaaacaaa gagcgcttgg aacgttttta caatgaattg
    12961 atcaacaaag actggttcat gactcttctt gatttggaag actacatcaa agtcaaagag
    13021 caaatgcttg ctgactacga agaccgtgac gcatggttgg ataaagtcat cgttaacatt
    13081 tctaaagcag gattcttctc atctgaccgt acaatcgctc agtataacga agacatctgg
    13141 cacttgaact aatactcttc gaaaatctct tcaaaccacg tcagctttat ctgcaacctc
    13201 aaagcagtgc tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    13261 gtataagata caaatttata ctaatacatt ttgtaaaaaa gcgagtttcg attgaaattc
    13321 gcttttttaa tgatgtagat ttgggtcaat cttgtctaaa aatagggaaa tcctagatac
    13381 agtgaaggct ttaaatgctg gtttttactg tcctcagcct tatatttttt cgtagttggt
    13441 tacctcatat ctattatatt cgcttacata aagtattata atataattgt aggaaagaag
    13501 gtgtttttat gatatacaca cttaaattgg tgttgtttat tacctttctt gtaataagct
    13561 tgttacctga taagattttt ggaaaaaata aaaaaatttg gaaaatagtt tttgcaatat
    13621 tgacggcagt ggcagcattg tcatttatgt actaagttat tttaagaatg tagggaaata
    13681 aaccctacat tctttttagt tttttctgtt ttctaaattc tatttatcca agcgattcaa
    13741 catttcttgc ttcttcgctt caagttctgc acgcttttct tcgatttcgg catgtttttt
    13801 ctcgagttca gaacaacttg caccattgct aaattctttt cgccatcagg agatagggtg
    13861 agtcgacatg tctattactc acccaaagca gtcctacaaa gcaggaattt tctgttactt
    13921 ttttggaaat agtaacgttt atacagcttt gacacttcgt atcaaagcgc caaacacact
    13981 ccgagggatt tacagaaagc agaaaaggaa tgatctggta taagatcatt ccttttctct
    14041 ctttttcttt aagtaattat atacaatgta cgacgaagtc gtcattgcaa tgctgatcca
    14101 ccacctaaag ggaactttaa acaacattga taagataaag aatataaaca acgaaaatac
    14161 gttataccca attaatttta ttgtatatct catgattaaa agttaatcct tccgttgtta
    14221 ggaatggcat catttttatc ccataattgt gctaaataag tccccggtga taataaattc
    14281 atagcgaatt ctaaagcaac atcatttaca aaccaactac ctagatatct agaaattgct
    14341 gaacgaatag cactttttgc tgcatgtttt ccttttactt taattagatt tgcaaggcct
    14401 gcagtagttc ctcctaatgc taaagctatt gcagtatcta atagagcacc catttgatta
    14461 actgtaatac cttgccaaac tgctctaaat ggagagtatg taggtgggat tgtataatcg
    14521 ccttgtaatt gtcggttaat tacttctttg atccattgtt gtgagacgtc tggatgaaaa
    14581 gattggattt cgtttgcaag tgtattgatt tgttcttctg ttagagaagt gacaggttga
    14641 agttccatat ttgtttcaat ttgtgatact tgttcagaag cgtatacagc tgaaacactt
    14701 ggaatcgctg atacaattaa cacaattgac gtcaaaaaaa ccgaaataaa tttcattaat
    14761 ttgttcatga gcttttctcc tttttatttg catctgctta cattttatca tatactgtta
    14821 ttatagtcaa aaaaatatgc tattatgtta aaaaaatatt tttcaaaata taaatggacg
    14881 gatttatttt ggattttatt tgttattttg acctgcctct atattggtaa ccatgatttg
    14941 tttactctca atcatcaaga attctctttt cgtggtagcg tttggggtct ggtactggcc
    15001 ttatatcact tactattcat tgataagttt gttatatcga atcgaaaata aagattagag
    15061 ctatgcttga ctgtgtactt ttaggattta ttttggagga agattttgtc tctattattt
    15121 attattttaa atttatttat tttgtataag atctattctt tgaggcggga aaaatcgaaa
    15181 tacttgattt atacggccta tatcatattt ggggtaaatg tagtatatgg tattcaatgg
    15241 ttattaaaag aactgatttc aactatttcc ccttaatgtg tatggaaact ataacaaaac
    15301 gcataagatt aaggtttgtg tacctgttct tatacgtttt tgtcatattg aagattttcg
    15361 gtaagttttc tacttttgcg aagtctagtt tatactcaat gaaaatcaaa gagtaaacta
    15421 gccgtaggtt gctcaaagta cagctttgag gttgcagat
//
LOCUS       DAVDHC010000044        15119 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVDHC010000044 DAVDHC010000000
VERSION     DAVDHC010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.044"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            9..89
                     /locus_tag="VUR43_001956"
     tRNA            9..89
                     /locus_tag="VUR43_001956"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:43..45,aa:Tyr,seq:gta)
     gene            94..164
                     /locus_tag="VUR43_001957"
     tRNA            94..164
                     /locus_tag="VUR43_001957"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:126..128,aa:Trp,seq:cca)
     gene            179..251
                     /locus_tag="VUR43_001958"
     tRNA            179..251
                     /locus_tag="VUR43_001958"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:212..214,aa:His,seq:gtg)
     gene            265..336
                     /locus_tag="VUR43_001959"
     tRNA            265..336
                     /locus_tag="VUR43_001959"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:297..299,aa:Gln,seq:ttg)
     gene            346..429
                     /locus_tag="VUR43_001960"
     tRNA            346..429
                     /locus_tag="VUR43_001960"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:380..382,aa:Leu,seq:caa)
     gene            536..1813
                     /locus_tag="VUR43_001961"
     CDS             536..1813
                     /locus_tag="VUR43_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET5413596.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1889..3373
                     /locus_tag="VUR43_001962"
     CDS             1889..3373
                     /locus_tag="VUR43_001962"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET5413597.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALCEKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPVRHKTTVAAADMQAAVEAYLGL"
     gene            3434..4714
                     /locus_tag="VUR43_001963"
     CDS             3434..4714
                     /locus_tag="VUR43_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET5413598.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYEKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4718..5338
                     /locus_tag="VUR43_001964"
     CDS             4718..5338
                     /locus_tag="VUR43_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET5413599.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5504..6646
                     /locus_tag="VUR43_001965"
     CDS             5504..6646
                     /locus_tag="VUR43_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET5413600.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVAERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7052..7390
                     /locus_tag="VUR43_001966"
     CDS             7052..7390
                     /locus_tag="VUR43_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET5413601.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            7401..7760
                     /locus_tag="VUR43_001967"
     CDS             7401..7760
                     /locus_tag="VUR43_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET5413602.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            7867..8511
                     /gene="pcp"
                     /locus_tag="VUR43_001968"
     CDS             7867..8511
                     /gene="pcp"
                     /locus_tag="VUR43_001968"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET5413603.1"
                     /translation="MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTIF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(8539..9396)
                     /locus_tag="VUR43_001969"
     CDS             complement(8539..9396)
                     /locus_tag="VUR43_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET5413604.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9526..10668
                     /gene="tgt"
                     /locus_tag="VUR43_001970"
     CDS             9526..10668
                     /gene="tgt"
                     /locus_tag="VUR43_001970"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET5413605.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10766..12583
                     /locus_tag="VUR43_001971"
     CDS             10766..12583
                     /locus_tag="VUR43_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET5413606.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIVGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12736..13887
                     /gene="nagA"
                     /locus_tag="VUR43_001972"
     CDS             12736..13887
                     /gene="nagA"
                     /locus_tag="VUR43_001972"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET5413607.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14050..15108
                     /locus_tag="VUR43_001973"
     CDS             14050..15108
                     /locus_tag="VUR43_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET5413608.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
BASE COUNT         4397 a         2699 c         3504 g         4519 t
ORIGIN      
        1 tatattttgg aagggtagcg aagaggctaa acgcggcgga ctgtaaatcc gctccttcgg
       61 gttcgggggt tcgaatccct ccccttccat tttacgggca tagtttaaag gtagaactaa
      121 ggtctccaaa accttcagtg tgggttcaat tcctactgcc cgtgttaata gaattatggc
      181 gggtgtggtg aagtggttaa cacaccagat tgtggctctg gcatgcgtgg gttcgatccc
      241 catcactcgc ctattttata ttattggggt atagccaagc ggtaaggcaa gggactttga
      301 ctccctcatg cgttggttcg aatccagcta ccccagttac tatttgccgg cgtggcggaa
      361 ttggcagacg cgctggactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg
      421 ccgccggtat agtatagtgt taggaacgtt gttattcttc gttccttttt tatattattt
      481 ttggtataat tatagttatt caaattttat ttagattgag aaagcgtagg gtagtatgtc
      541 ttgttctatc gatttattaa aacaccggta tttgaaaaat attaaagaaa atcctgaatt
      601 gtttgtcgga attgagttgg agtatcctgt tgcaagttta gaaggggatg ctacagatgt
      661 tgaagttata aaggatctat ttcattattt agtttctact ttggatctca ccgtagcaaa
      721 ggtagatgat tttggcaatc tgatccagtt agtagatccg ataagtcagg atgctatttt
      781 atttgaagtt tcctatacaa cgattgagtt tgcatttggt aaggctgaaa cgattcaaga
      841 ggtcgaaaat cgtttcaata attatatgaa tgtaattcag agaaagttag ctgaatcaaa
      901 tcatgctatt gttggctgtg gtatccatcc caactgggat aaaaatgaga attgtccagt
      961 ggcttatcca cgctatcaga tgttgatgga ttatttgaat ttgagtagaa atattattaa
     1021 atcagattta catcatttcc ctgaatatgg tacttttatc tgtgggagcc aggttcagct
     1081 ggatatttca aaaaccaact acttacgggt gattaatgct tttactcaaa ttgaagcggc
     1141 taaggcttat ttatttgcaa actctgagtt ttcgggtgcg gattgggata cgaaaatttc
     1201 aagggatatt ttctgggaag aatctatgca tggtatctat ccagagaatg ttggggtcaa
     1261 tgctagactc cttaatgatg aagctgattt ttttgactat ctaaatcatt ctgcgatttt
     1321 tactgcggaa cgtgatgggc agacctatta tttttatcct attcaggctg gggactattt
     1381 ggctacgcct gaaatccaag catttgctct gaatggggat gaggttatta tttcccccca
     1441 agagaaggat tttgaaactc atcgtagtta ccagtaccaa gacttaacga ctcgaggaac
     1501 agttgagttt cgtagtgtgt gtacacagcc acttgatagg acttttgctt ctgcagcttt
     1561 tcacttggga ttattggtta atttagacaa gttagaagct tacttagaaa cagcaccttt
     1621 ctttaaagta tttggttatg attacaagtt tttaaggaga caattttcta agaaaaatct
     1681 tacagatgag gaagaaacta cgattattga attttccaaa gacttactcc tactagctga
     1741 ggagggacta gtggtgagaa ataaggaaga aatgacctat ttacagcctt tgagagaaga
     1801 attgagccta taatttctct tataaaggga gaattttctg aaaaatcatg atataatgga
     1861 cgagactata gataaaggat agagagtaat gacattagtt tatcaatcaa cgcgtgatgc
     1921 caacaataca gtaactgcca gccaagcaat tttgcaaggt ttggcgacgg acggcggttt
     1981 gtttacaccg gttacttatc caaaggtaga tttggacttt gacaaattga aagatgcttc
     2041 ttatcaggaa gttgctaagc tagttttgtc agcattttta gatgacttta cagctgagga
     2101 gttggactac tgtatcaaca atgcctacga tagcaaattt gatactccag ctattgcacc
     2161 attagtgaaa ttagatgggc aatacaattt ggaacttttc catggttcaa cgattgcctt
     2221 taaggatatg gccttgtcta ttttgccata ctttatgacg actgctgcta agaaacatgg
     2281 tttggagaac aagattgtta tcttgacagc gacatctggt gacacgggga aagctgctat
     2341 ggcggggttt gcggatgtgc ctggtactga gattatcgtc ttttatccaa aggatggtgt
     2401 cagcaagatt caagagttac aaatgaccac tcaaactggc gacaatactc atgttattgc
     2461 tattgatggt aactttgacg atgcgcaaac aaatgtgaag cacatgttta acgacgtggc
     2521 tctttgtgaa aaattgacta ccaacaagtt gcaattttca tcagctaact ctatgaacat
     2581 tggtcgtctg gtgccacaga ttgtttatta tgtttatgcc tatgctcagt tggtcaagac
     2641 tggtgagatc gtggctggtg ataagattaa cttcacagta ccaacaggaa actttggaaa
     2701 tatcttggct gccttttatg ccaaacaaat tggtttgcca gttggtaaat taatctgtgc
     2761 ttcaaatgac aataatgtct tgacagactt ctttaaaaca cgtgtctatg acaaaaaacg
     2821 tgagtttaag gtaacaacca gcccatctat ggatatcttg gtatcttcaa acttggagcg
     2881 cttgattttc catcttttgg gaaataatgc tgaaaagaca gctgaactta tgaatgcctt
     2941 gaacacgcaa ggacaatata agttgacaga ctttgatgca gagattttgg acctctttgc
     3001 agctgaatat gcgactgagg aagaaacggc agcagagatc aagcgtgttt gtgagttaga
     3061 ttcttatatc gaggaccctc atacagctgt tgcttcagca gtttataaaa aataccaatc
     3121 ggccactgga gatgtaacta agacagtgat tgcttcaaca gctagtccat acaagttccc
     3181 agtagttgca gtagaagctg taactggaaa agcaggttta acagactttg aagccttggc
     3241 tcaattacat gaaatctcag gcgttgcagt gccaccagca gttgatgggc ttgaaatagc
     3301 tcctgttcgt cacaagacaa ctgtagcggc tgctgatatg caagcagcgg ttgaggctta
     3361 tttaggactt taagatagag ggagtaaact cggttgggaa accaactgag tttcttttca
     3421 tcaggaggag agattgttta agaaaaataa agacattctt aatattgcat tgccagctat
     3481 gggtgaaaac tttttgcaga tgctaatggg aatggtggac agttatttgg ttgctcattt
     3541 aggattgata gctatttcag gggtttcagt agctggtaat attatcacca tttatcaggc
     3601 gattttcatc gctctgggag ctgctatttc cagtgttatt tcaaaaagca tagggcagaa
     3661 agaccagtcg aagttggcct atcatgtgac tgaggcgttg aagattacct tactattaag
     3721 tttcctttta ggatttttgt ccatcttcgc tgggaaagag atgataggac ttttggggac
     3781 ggagagggat gtagctgaga gtggtggact gtatctatct ttggtaggcg gatcgattgt
     3841 tctcttaggt ttaatgacta gtctgggagc cttgattcgt gcaacgcata atccacgtct
     3901 gcctctctat gttagttttt tatccaatgc cttgaatatt cttttttcaa gtctagctat
     3961 ttttgttctg gatatgggga tagctggtgt tgcttggggg acaattctgt ctcgtttggt
     4021 tggtcttgtg attttgtggt cacaattaaa actgccttat gagaagccaa cttttggttt
     4081 agataaggaa ctgttgacct tggctttacc agcagctgga gagcgactta tgatgagggc
     4141 tggagatgta gtgatcattg ccttggtcgt ttcttttggg acggaggcag ttgctgggaa
     4201 tgcaatcgga gaagtcttga cccagtttaa ctatatgcct gcctttggcg tcgctacggc
     4261 aacggtcatg ctgttggccc gagcagttgg agaggatgat tggaaaagag ttgctagttt
     4321 gagtaaacaa accttttggc tttctctgtt cctcatgttg cccctgtcct ttagtatata
     4381 tgtcttgggt gtaccattaa ctcatctcta tacgactgat tctctagcgg tggaggctag
     4441 tgttctagtg acactgtttt cactacttgg gacccctatg acgacaggaa cagtcatcta
     4501 tacggcagtc tggcagggat taggaaatgc acgcctccct ttttatgcga caagtatagg
     4561 catgtggtgt atccgcattg ggacaggata tctgatgggg attgtgcttg gttggggctt
     4621 gcctggtatt tgggcagggt ctctcttgga taatggtttt cgctggttat ttctacgcta
     4681 tcgttaccag cgctatatga gcttgaaagg ataggaaatg caaaaaacag cttttatttg
     4741 ggatttagac gggactttat tggactctta cgaagcgatt ttatcaggga ttgaggagac
     4801 ttttgctcag ttttctattc cttatgataa ggagaaggtg agagagttta tcttcaagta
     4861 ttcggtgcaa aatttgcttg tgcgggtggc agaagataga aatctggatg ttgaggtgct
     4921 aaatcaggtg cgtgcccaga gtctggctga gaagaatgct caggtagttt tgatgccagg
     4981 tgcgcgtgag gtgctagctt gggcagacga atcaggaatt cagcagttta tatatactca
     5041 taaggggaac aacgctttta ccattctcaa ggacttgggg gtggaatcct attttacaga
     5101 gattttaacc agtcagagtg gctttgtgcg gaagccaagt ccagaagcgg ctacctatct
     5161 gctagataag tatcagttga attctgataa tacttattat ataggggatc ggactctgga
     5221 tgtggaattt gcccagaata gtgggattca aagtatcaac tttttagagt ctacttatga
     5281 agggaatcac aggattcaag cgttagcaga tatttcccgt atttttgaga ctaagtgata
     5341 aaaagattgt gtcagttttg tgacagagac ctaacaaact atttcaagta acctagtttg
     5401 ttacaaggag tagacagttc tgttaaatag gaccgagagg gctttttttc tacatttttt
     5461 gtgttatgat agacaggtac tcatttgaaa ggaatttgaa agaatgaaga aaagaatgtt
     5521 attagcgtca acagtagcct tgtcatttgc cccagtattg gcaactcaag cagaagaagt
     5581 tctttggact gcacgtagtg ttgagcaaat ccaaaacgat ttgactaaaa cggacaacaa
     5641 aacaagttat accgtacagt atggtgatac tttgagcacc attgcagaag ccttgggtgt
     5701 agatgtcaca gtgcttgcga atctgaacaa aatcactaat atggacttga ttttcccaga
     5761 aactgttttg acaacgactg tcaatgaagc agaagaagta acagaagttg aaatccaaac
     5821 acctcaagca gactctagtg aagaagtgac aactgcgaca gcagatttga ccactaatca
     5881 agtgaccgtt gatgatcaaa ctgttcaggt tgcagacctt tctcaaccga ttgcagaagc
     5941 tccaaaagaa gtagcatcaa gttcagaagt tacaaagaca gtgattgctt ctgaagaagt
     6001 ggcaccatct acgggcactt ctgtcccaga ggagcaaacg gccgaaacaa ctcgcccagt
     6061 tgaagaagca actcctcagg aaacgactcc agctgagaag caggaaacac aagcaagccc
     6121 tcaagctgca tcagcagtgg aagcaactac aacaagttca gaagcaaaag aagtagcatc
     6181 atcaaatgga gctacagcag cagtttctac ttatcaacca gaagaaacga aagtaatttc
     6241 aacaacttac gaggcaccag ctgcgcccga ttatgctgga cttgcagtag caaaatctga
     6301 aaatgcaggt cttcaaccac aaacagctgc ctttaaagaa gaaattgcta acttgtttgg
     6361 cattacatcc tttagtggtt atcgtccagg agacagtgga gatcacggaa aaggtttggc
     6421 tatcgacttt atggtagcag aacgttcaga attaggggat aagattgcgg aatatgctat
     6481 tcaaaacatg gccagccgtg gcattagtta catcatctgg aaacaacgtt tctatgctcc
     6541 attcgatagc aaatatgggc cagctaacac ttggaaccca atgccagacc gtggtagtgt
     6601 gacagaaaat cactatgatc acgttcacgt ttcaatgaat ggataaaccc gacttgataa
     6661 catcattttg acgaatgaga tctagctttc gtgatggaaa gcgattctcg ttcgtttttt
     6721 ctttgtcata ctcttcgaaa atctcttcaa accacgtcag ttttatatga aacctcaaag
     6781 ctgtgctttg agcaacctgc gactagcttc ctagtttgct ctttgatttt cattgagtat
     6841 caatttgaat ggaaaatgga aagttattat cttgtaataa tccaagcaac attcttgcaa
     6901 tctattttac tttatatcac aattgattgg tcaactattg ataagtcaat ggataggagg
     6961 aagaaatgat agagattcaa gatttactgt atcaactccg cttgtctgag caagcgagta
     7021 cgcaattgtt tgaaaaaggc ttgggattag tttgacacgg tatcagattt tactgttttt
     7081 gctggagcat tctccttgta accaaatggc ggttcaggag cgtttgaaaa ttgatcaggc
     7141 tgctttgaca cggcatttca agattttgga aacggaaggt ttggtggagc gtcatcgtaa
     7201 tcctgaaaat cagcgggaag tgttggtaga ggctgcgaag tatgccaagg agcagttagt
     7261 ggtgaatccc cctctgcaac atatcaaggt taaggaagag atggaaagta tcttaacaga
     7321 gtttgagaga acagaactca gccgtttatt aaataaattg gttttgggta ttgaaaatat
     7381 agaaatttaa ggagaaatag atgtcaatta ttttaacaac gatcgttgct ttggagcatt
     7441 tttacatttt ttatttggaa agtattgcca cgcaatcaga tgcgactagt cgtgtattta
     7501 atatggaaaa ggaagaattg gctcatccgt cagtaagttc attgttcaaa aatcaaggaa
     7561 tttataaggc tctgctagga gtctttctct tgtatgtcat ttatttctca cagaatttag
     7621 aaattgtgac tatttttgtc ttatttgtga ttggtgctgc gacttacggc tctttaacag
     7681 cggataaaaa aattattttg aaacaaggtg gatcagctat tttggccttg attagtattt
     7741 tactctttaa atacacttga aggtcgattc taatctcgct aatccttttt aatccagaat
     7801 aagggaaata tgttatactt gtttttaaga aaaaagtctc attgaattgg ttttgaggag
     7861 ttagaaatga aagtattagt gacaggtttt gagccctttg gaggggaaaa gggcaatcca
     7921 gctttggagg ccattaaagg tttaccagct gaaatccatg gtgctgaggt ccgttggcta
     7981 gaggtgccga caatttttca caaatctgct caagtattgg aagaagagat gaatcgttat
     8041 caacctgact ttgttctttg tattgggcaa gctggtggaa gaactagttt gacacctgaa
     8101 cgagtggcca ttaatcaaga cgatgcacgc atttctgata acgaagataa tcaaccgatt
     8161 gaccgtccca ttcgcccaga tggtgcttcg gcctacttta gtagtttgcc gattaaagcg
     8221 atggttcaag ctataaaaaa agagggctta ccggcctctg tttccaatac ggcagggact
     8281 tttgtctgca gccatttgat gtatcaggct ctctatttgg tagaaaagaa atttccatat
     8341 gttaaggcag gttttatgca tattccttat atgatggaac aggtggtgaa cagaccgact
     8401 actccaacta tgagtttagt ggatattcgg cgagggatag aagcagcaat cggcgctatg
     8461 atagaacatg gagatcagga actcaagttg gtaggcggag aaactcattg atagaaaaaa
     8521 gcttgagggg aaaaaccttc aagcttttgg acgttttcga gccaatactg ctcggtaaaa
     8581 cataatttta gtgcattgga tataaggtag gagtgaaaaa ctagcaatgc caaaggtaat
     8641 ccaattgagg aagtaccaag gaagaagctg taaatctagg acaaagtgct ggaacttgta
     8701 gcccttcata aaggaacggc tagtttttag gattcgtctt ggtgggacct gtcctaggtc
     8761 tagactataa cagagaagaa attccacctg tgaataggca taatactgtg gaatatagag
     8821 gatattccct acaatgatca agatgagact tgcaagaaag tagagtccaa agaccatgag
     8881 gaaacgctcg gtttcaactg atgagagatc tagatttgga aactcaggat gtagggtgac
     8941 gaattttttg gctaaaaagc tactataaaa gaggaggtaa atcccaagta aattagggat
     9001 actccataaa aagagataga aacgtttgag aagtagggtc aaaaaggttt gagaaaagcg
     9061 ctcctcatca aagagagcta ggctgttttt tacagatggc tccgttttag aatctttcat
     9121 gagtgtcagt gttgcataga cggaactggt caaaagaata gtcccgataa aggagactag
     9181 tagaggaaag aggtaggctt gaagtatttg gccaagtatg ctgaaaaatg gctgttctaa
     9241 aacagtcccg tggatccgag ataagggatt aagaaaacta gataagatga ccagcatact
     9301 gggaaggata tagaggagaa agagacgggg ggtgtcagcc tgaaaatgtt ttgactcctg
     9361 acgaattgtt tttaaatcaa tttttggata gttcattctc ttattatacc atagttctta
     9421 tacatagttc gtgacagttc ctactttttt tgataaaatc atacagtgtg tccttgggca
     9481 cactgtatga actgggactg tctttcccag cttcggaggt aaaaaatgtc agattcacca
     9541 atcaaatatc gtttgattaa gaaagaaaaa cacacaggag ctcgtctagg agaaatcatc
     9601 actccccacg gtacctttcc gacacctatg tttatgccag ttgggacaca agccactgtc
     9661 aaaactcagt cacctgaaga attgaaggag atgggttcgg gaattatcct atcaaacacc
     9721 tatcatctct ggcttcgccc tggagatgaa ctcattgcac gcgctggtgg tctccacaag
     9781 ttcatgaatt gggaccagcc tatcttgaca gatagtggtg gttttcaggt ttattcttta
     9841 gcagatagcc gtaatatcac agaagaagga gtaaccttta aaaatcatct aaatggttct
     9901 aagatgttcc tatccccaga aaaagccatc tctattcaga ataatctggg ttcagacatc
     9961 atgatgtcct ttgatgaatg tcctcagttt tatcaacctt atgactacgt taagaaatcg
    10021 atcgagcgta ccagccgttg ggctgagcgt ggtttgaagg ctcaccgtcg tccacatgac
    10081 caaggtttgt ttggaattgt gcaaggtgca ggatttgaag accttcgccg ccaatcagct
    10141 catgatcttg tcagcatgga tttctcaggc tactctatcg gtggtttggc agtgggagaa
    10201 acccatgaag agatgaatgc ggtcttggac tttacaactc aactgctacc tgaaaataaa
    10261 cctcgttatc tgatgggtgt gggagcgcca gatagcttga tcgatggggt cattcgtggg
    10321 gtggatatgt ttgactgtgt cttaccgact cgaattgctc gtaacgggac ttgtatgacc
    10381 agtcaaggac gtttggttgt gaaaaatgcc cagtttgctg aggactttac gccactggat
    10441 cctgagtgtg actgctacac atgtaataac tatacacgcg cttaccttcg tcacctgctc
    10501 aaggctgatg aaacctttgg tatccgcttg actagctacc acaatcttta cttcttgctt
    10561 aacctgatga agcaagtgcg acaagccatc atggatgaca atctcttgga attccgtgag
    10621 tattttgtgg aaaaatatgg ctataataag tcaggacgta atttctaaaa tggaattgat
    10681 ataaaaaaat cctaagtttt ctcttaggat ttttcttctt tttttgatag aataaagtgt
    10741 acaatgaaag gaagaataaa ctcgtatgcg cattaaatgg ttttccttga ttaggattat
    10801 aggtttactt ttggtactct tgtatcactt ctttcagacg atctttcctg gaggattttt
    10861 cggggtagat gtctttttca cattttcagg tttcctgatt acagctctac tcattgaaga
    10921 attttctaaa aaccatgaga ttgatttgat aggatttttt agaagacgct tttatcggat
    10981 tgtgccacct gtggttttga tggtcttggt gaccatgcct tttactttct tggttcgcca
    11041 agactatgtt gctggaattg gtggccagat tgcgggcgtc ttaggcttta tgaccaactt
    11101 ctatgaactc ctaacaggtg ggagttatga atctcagttc attcctcatt tgtttgttca
    11161 taattggagt ttggcagttg aggttcacta ctatattctt tggggattgg cagtttggtt
    11221 cttatccaaa caagctaaat caaatggtca gttgaagggg atggtctttc tcttatctgc
    11281 tgttgccttc ttgatcagtt tcttctccat gtttattggt agttttctag tgacctctta
    11341 ttcctctgtt tatttctcca gtttaactca tgtctatcca ttctttttgg gaagtatgtt
    11401 agcaactatt gtaggcgttc gtcagacgac ttccctcgtc aagcagttgg ataaaatctg
    11461 ggatttacga aagactttgg tagtttttgg aggaggcttt ggtttcctag ttcttttgac
    11521 tttctttgtc aaattcactt atctttttgc ctatcttatc ggcttcttgc ttgccagtct
    11581 tgcagctctt gccatgattc tggcggcgcg tgtcttacat gaaaagacac atcatataca
    11641 ggagccgaag attatcagct ttctagcgga tactagctat gcggtttatc ttttccattg
    11701 gcctttctat atcattttct cacagttgac atcaaatctt cttgctgtat tactgactct
    11761 gatttgttct tatggctttg ccagtctgtc attctatgta ttggaacctt ggattgtagg
    11821 caagaacaca cctattttac aaactcttcg tcccctgcct tatattcacg caattcttgc
    11881 agcaggtaca ggaatcttga ccttcattgt ctgcatggtg accttgttgg caccacaagt
    11941 gggagcgttt gagacagact tgactgtcaa tggcttgaag caagctgcaa caaatattgg
    12001 ccagaccaag gtgatggcag aacgggcaga tgcaaacagt ttgggaattg ctgatggcac
    12061 tatgttaatt ggtgactcag tggctttaag ggcaaataca gcactacaga cagctcttcc
    12121 tggagcacag attaacgcgc aggtcagcgt aacaaccaag accgcaaatg aaatcatgct
    12181 aaataatagc cagaataaat ttttacctaa gacggtggtc attgcgactg gggtaaataa
    12241 tcctgagaat tacaaggatg actgggacag tatcgtgaaa aatcttccta agggacacca
    12301 tatgattttg gtgactcctt atgagggaga taagacaaaa gagacctatg ccatcgttga
    12361 gaaggctgct gcctatatga gagaattggc agagaagaca ccttacatta cgatagcaga
    12421 ttggaatcaa gttgcgaaag agcatccaga aatttgggca ggaacagacc aggttcattt
    12481 cgggagtgag agtagcacta tcgaagcagg agcaaaattg tatgcagata cgattgccac
    12541 agctttgcag acagctcaag acaagccggt taaatcaaaa taacttgtat taaaaaagag
    12601 aagagttgga gaaatccagc tcttttaaaa tatctccaaa aaataggtct ataccattta
    12661 caaataaaaa agaaaggttt ataatgtaat tgacataata aattgcagaa tcaatctttt
    12721 aaggaggtta acattatgcc taactatatt aaagcggatc agtttttcta cccacacgga
    12781 gttcgtcgag gtggttactt ggaacttgtg gacggcaagt ttgggaaaca tgtagagcag
    12841 attcctgaag gggctgaggt gattgactat acaggttata gcattgcccc aggtcttgtg
    12901 gatactcata ttcatggata tgcaggtgta gatgtgatgg acaacaacat tgaaggtaca
    12961 ttgcatacta tgagtgaagg acttcttagt accggtgtta ccagtttctt acccacaact
    13021 ttaacagcca cttatgagca attgcttgca gtcactgaaa atcttggaaa ccattataaa
    13081 gaagcaacag gtgctaagat tcgtgggatt tattatgaag gtccatattt cacagaaact
    13141 tttaaggggg cacaaaatcc aacttatatg agagacccgg gtgttgagga gtttcattct
    13201 tggcaaaaag cggcaaatgg cttgcttaat aaaattgccc ttgcaccaga acgtgatggg
    13261 gtggaagact ttgttcgtac agttacgggc gaaggtgtga cggttgctct tggacattca
    13321 aacgcgactt ttgatgaagc caaaaaagca gtcgatgctg gagcgagtgt ttgggtgcat
    13381 gcctacaatg gaatgcgtgg gttgactcac cgtgaattgg gtatggttgg agccatgtac
    13441 caattgccac atacctatgc agagttgatc tgtgatggtc accacgtaga tccaaaggct
    13501 tgcgaaattc ttatcaaaca aaaaggaaca gaaaacatcg ctcttatcac agactgtatg
    13561 acagctgggg gattggaaga cggagattat atgttgggag aattcccagt tgtcgttgca
    13621 aatggaactg cacgcctcaa atcgacaggt aacttggcag gttctatcct caaactcaaa
    13681 gatggtttga agaatgtggt cgaatgggga attgcgaatc cgcatgaagc agtcatgatg
    13741 gccagcttca acccagctaa atccgttcac atcgatgacg tctgtggcca aatccgtgaa
    13801 ggctacgacg ctgacttcat cgtattagat aaagatttgg aattggtagc aacctaccta
    13861 gatggcgtaa aacgttatca agcataagag agaaagcaga agttagagac taacttctgc
    13921 ttttttatgc agggtacttt actggtaaat aaaaagttaa aaaaatcaca aaaaaagctt
    13981 gaagaaacaa agaaaaaggc ttacaattga actataaata ttacaaataa aaaaacggag
    14041 gagtgcttta tgaaagccta tacttatgtt aaaccaggac ttgcttcttt tgttgatgta
    14101 gacaaaccag ttattcgcaa gccaacagac gctattgtgc gtattgtaaa aaccactatt
    14161 tgtggaacag acctccatat tatcaaaggg gatgttccta cttgccaaag tggtaccatt
    14221 cttggccacg aagggattgg gattgttgaa gaagttgggg aaggagtttc caacttcaaa
    14281 aaaggtgaca aggtcttgat ttcttgcgtc tgtgcctgtg gtaaatgcta ctactgtaaa
    14341 aaaggaattt atgctcactg tgaagacgaa gggggctgga ttttcggtca cttgattgat
    14401 ggtatgcagg ctgaatatct acgtgtccct catgcagata atactcttta ccatactcca
    14461 gaagacttgt cagatgaagc tttggttatg ctgtcagaca ttctgcctac tggatatgaa
    14521 attggtgtct taaaagggaa agtagaacct ggttgcagcg tagccattat tggttcaggt
    14581 ccagttggat tggctgctct tttaacagcc caattctatt caccagctaa attgattatg
    14641 gtagacctag acgataaccg cttggaaact gccctatcat tcggtgcgac tcataaggtt
    14701 aattcttcag accctgaaaa agccattaaa gaaatttatg atttgacaga tggtcgtggt
    14761 gtggatgtcg ctatcgaagc tgttggtatt cctgcaacat ttgatttctg tcaaaagatt
    14821 atcggtgtag acggaacggt tgccaactgt ggtgtgcatg gtaaaccagt tgaattcgat
    14881 ttagataaac tttggattcg caacatcaat gtaacaactg gtttggtatc tacaaatacg
    14941 actccacaat tgttgaaagc gcttgaaagt cataagattg aaccagaaaa attggtaact
    15001 cactatttca aactcagtga aattgaaaaa gcctacgaag tcttcagtaa ggcagcagac
    15061 caccatgcca ttaaggtcat tatcgaaaac gatatctcag aagcctaagt agtaaaaat
//
LOCUS       DAVDHC010000045        14951 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVDHC010000045 DAVDHC010000000
VERSION     DAVDHC010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14951
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.045"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(1..745)
                     /locus_tag="VUR43_001974"
                     /pseudo
     CDS             complement(1..745)
                     /locus_tag="VUR43_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(881..1180)
                     /locus_tag="VUR43_001975"
     CDS             complement(881..1180)
                     /locus_tag="VUR43_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET5413609.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1345..1796)
                     /locus_tag="VUR43_001976"
                     /pseudo
     CDS             complement(1345..1796)
                     /locus_tag="VUR43_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            1878..2751
                     /locus_tag="VUR43_001977"
                     /pseudo
     CDS             1878..2751
                     /locus_tag="VUR43_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(2953..5211)
                     /locus_tag="VUR43_001978"
     CDS             complement(2953..5211)
                     /locus_tag="VUR43_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET5413610.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(5440..5670)
                     /locus_tag="VUR43_001979"
     CDS             complement(5440..5670)
                     /locus_tag="VUR43_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET5413611.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            5860..6543
                     /locus_tag="VUR43_001980"
     CDS             5860..6543
                     /locus_tag="VUR43_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET5413612.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            6543..7277
                     /locus_tag="VUR43_001981"
     CDS             6543..7277
                     /locus_tag="VUR43_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5413613.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKLIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            7431..8288
                     /locus_tag="VUR43_001982"
     CDS             7431..8288
                     /locus_tag="VUR43_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET5413614.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            8430..9302
                     /locus_tag="VUR43_001983"
     CDS             8430..9302
                     /locus_tag="VUR43_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET5413615.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEAMAFALQDKQLLKEQLEKAEVVLLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDTTASALTSFPKGTILVEKGPATRVWQAGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            9584..10267
                     /gene="rpiA"
                     /locus_tag="VUR43_001984"
     CDS             9584..10267
                     /gene="rpiA"
                     /locus_tag="VUR43_001984"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET5413616.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            10281..11492
                     /locus_tag="VUR43_001985"
     CDS             10281..11492
                     /locus_tag="VUR43_001985"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET5413617.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            11494..12036
                     /locus_tag="VUR43_001986"
     CDS             11494..12036
                     /locus_tag="VUR43_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET5413618.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            12052..12861
                     /locus_tag="VUR43_001987"
     CDS             12052..12861
                     /locus_tag="VUR43_001987"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET5413619.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            13337..14317
                     /locus_tag="VUR43_001988"
     CDS             13337..14317
                     /locus_tag="VUR43_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET5413620.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHT
                     NFQSKPWWQVDLAKEETIRQINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            14342..14854
                     /locus_tag="VUR43_001989"
     CDS             14342..14854
                     /locus_tag="VUR43_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET5413621.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         4405 a         2747 c         3267 g         4532 t
ORIGIN      
        1 atcaagtgtt gaactctttt atgatttacc agataaccac gatttcttag ttctaaataa
       61 atccgacgat aaccatagtt gcctttatgt tcattataaa tggcctgaat ttaggtttta
      121 atctctttat ctttatcaac cccatccagt tgtttcaact gataatagta agtcgagcga
      181 gctaaacgtg ctgtttcaag aagaaaatct agtcgaaatc ctcctgaaac catttctcta
      241 actgtctctg cctttctcgc tctagggctt cgtccctttc ctctaactct tttaactttt
      301 ttaggtaggc cacctcagtc cgtaagcgtt cattctcctc ctggagtcgt tctagttctg
      361 tcatttcttc ccaagtcttc ttccgtttac gtcccatttt agctggtctc cctcttgttt
      421 tctcaacaat agtatacccg tttttcttgt attgtgccag ccaaaatgaa agcattcctt
      481 ggtttgggag ggcataatca agactaacac ttctttgtga acaaccttcc agtaaggctt
      541 tatccatcat ttcttgtttc aatttagaag aatagtgacg attcttcccc tttttaacga
      601 tttctatgcc atgacggtca attaatttca ccatgtactt tagaccagaa acatccacac
      661 caaatctttt tgaaagctgt ttgaagcttt gtccttgctt tcttagttca tagatctgaa
      721 ctttatcttc ataacttaat ttcataataa aacaccccaa aagttagatt ttttctgtct
      781 aacttttagg gggcagttca tttcggcacc tgatactatg cgttttgtta tggaaagact
      841 tattggactt tctctcaaat cgagttttta ctcaattttc ttacttgatt gggattgaaa
      901 ttccaattaa tttctctgag tagagtgtct tgatattggc ttcatcaaca gaggtcttat
      961 caattttacg tttcaagaaa aattcttgaa tggtttcgat ttcaggctca cgaatagcac
     1021 ggtgtttgtt tgagatgagg atttcatagt gaagcggagc ttgggtaaaa ataacatctg
     1081 tattccctgc agaataaacc tcaacaaggg ttgcatcggt actttctagt tgacttttta
     1141 caagttgcga gtgtgagttt gtcgtattga taagcttcat aatatttcct ccgattttct
     1201 aattctatta taacactttt tgaataaagt cgcttgattt atactcaatg aaaatcaaag
     1261 agcaaactag gaagctagcc gcaggctata cttgagtacg gtaaggcgac gcttacgtga
     1321 tttgaatttt attttcgaag agtattagcc aatcttatgc tgttttttcc aagattcaat
     1381 ggcccattta tggctgccac gtttaaggtt tttgatagcc tcgtcaatag ggaaccaggc
     1441 aatatgatta aagttttcta gtggcttttg tacttctttg aaaggagttg cttcatagag
     1501 gtaggcagga ttgtagtagt aggtatcacg atgacgagaa tagaaatatt cgtcagctgg
     1561 tccgtaatag gtaccaattt ctgctgtgaa accaagctct tcaatcaact cacgctttag
     1621 ggcttcctga tgattttcac ctgcttcaat ttttccacat ggtaggaacc aagcaccatt
     1681 tggttcttga acaagaacaa tttgtttttg ttcaggatta gggataactg catatacgcc
     1741 atagcgagca atatagtctg tattcacttt ttttctccga aagttgggtt tgccattgca
     1801 ttttcctcat tatctagtat cgttattatt atagtgaaat gaaccaaaaa tagtacacaa
     1861 tgtggtataa tcttcttatg gcatattcaa tagattttcg taaaaaagtt ctctcttatt
     1921 gtgagcgaac aggtagtata acagaagcat cacacgtttt ccaaatctca cgtaatacca
     1981 tttatggctg gttaaagcta aaagagaaaa caggagagct aaaccaccaa gtaaaaggaa
     2041 caaaaccaag aaaagttgat agagatagac ttaaaaacta tcttactgac aatccagacg
     2101 cttatttgac tgaaatagct tctgaatttg gctgtcatcc aactaccatc cactatgcgc
     2161 tcaaagctat gggttacact cgaaaaaaag aaccacacct actatgaaca agagccagaa
     2221 aaagtagcct tatttcttaa gaattttaat agattaaagc acctagcacc tgtttagatt
     2281 gacgaaacag gattcgatac ttatttttat cgagaatatg gtcgctcatt aaaaggtcag
     2341 ttaataagag gtaaagtatc tggaagaaga tatcagagga tttctttggt tgcaggtcta
     2401 acaaatggtg agttaatcgc tccaatgact tacgaagaga tgatgacgag cgactttttt
     2461 gaagcttggt ttcagaagtt tttcttacca acattaacca caccatcggt tattattatg
     2521 gataatgtaa gattccatag aatggggaag aatgtaagat tccatagaat ggggaagcta
     2581 gaacttttat gcgaagagtt tgggcataaa cttttacctc ttcctcccta ctcgcctgag
     2641 tacaatccta ttgagaaaac atgggctcat atcaaaaagc acctcaaaaa ggtattacca
     2701 agttgcaata ccttttacga ggctcttttg tcctgttctt gtttcaattg actatagcag
     2761 attgaaatga gaacaaatcg attgggaaag taaaattaat ttctataaat gttttagcaa
     2821 ttgtttcgta ctatttcaga ttcagtctac tatatatcat aatggacaaa gggcaagctg
     2881 tcaagaaatt acagttattt tagtaaaaaa agaagcagaa aaatttcatt ttctactcct
     2941 tttctatagg atttattttt ctttttcaga acttttaact tcagcttttt tggcagattt
     3001 aatctgaatg tttcccttgc tagtcataac tgctttgaga tctttttcgc ttggattttc
     3061 aaggtagtag tcagtgattg tgtcctcaat atagtcttga atagtccgac gaagtgggcg
     3121 tgctcccatt tttggatcat aacctaggtc aaccaacttt tccttgacct tatcagttac
     3181 atccaaacga atgttgttgc tagagaggcg cttgttaaca tctgctagca tgagctcgac
     3241 aatctgaagg aggttatcct tgctgagagc cttaaattcg ataatgccat caaaacggtt
     3301 cataaactct gggctaaaga agttaccgag ttcaccgagg acagaattgg tacgtccttc
     3361 tctagcagca ccaaatccaa cgctagcttc ggtctttcct gtacctgcat ttgaggtcat
     3421 gataatgatg gcatccttga agctaacggt gcgtccttgc ccgtctgtca aacgaccatc
     3481 gtccaagact tgaagaaaca tgtgcataac atctgggtga gctttttcca cttcatcgag
     3541 aaggatgaga gaatatggat tgtggcgaac tttttcagtt aattgaccag cctcatcata
     3601 gccaacataa cctggaggag cgccgaccaa cttagccaca ctatgttttt ccatgtattc
     3661 actcatatca aagcgaatca tactatcagc agaaccaaaa agttcgatag ccagttgttt
     3721 ggaaagttct gtcttgccga caccagttgg cccaacgaag aggaagcttc cgattgggcg
     3781 gttaggggta ccaagtccga cacgattacg gcgaatagcc ttggcaatct tatcgactgc
     3841 atcatcttgg ccaataacat gagacttgag atcttcggct agatggatga gttgagattg
     3901 ttctttctct ttcaaatcac caacagggat attggttttc tgctcgataa tgtgctcaat
     3961 agttttctcg ctgatgatag gagtatcctg gtctgtgatc tttttctttt gcatttcctt
     4021 atacttggca atctggtcgc ggaagtaggc cgccttctca aaatcttctt ctcgtgtagc
     4081 ttgagacttg agattttcag cctcaatcaa gcgctgatca attactttag gatccacaaa
     4141 attcaaggtc aagttcatct tagaaccagc ttcatctagg aggtcaatgg ccttgtcagg
     4201 caagaagcga tcttggatgt agcgattgga aagagttgca gctgcttcaa tcgcagcatc
     4261 ggtatattga acgtggtggt aatcttcgta tttcttttga atccctttga gaatagtgat
     4321 tgtttcatcc accgttggtt catcgacttt aacaggctgc atacgacgct cgagggcagc
     4381 atccttttca atgatacggt attcattgag ggtagtagca ccgactagtt gcagttctcc
     4441 acgagcaagg gctggcttga ggatatttcc tgcgtccata ttaccatcac tcgcagaacc
     4501 agcaccaaca atttcatgga tttcatcgat aaagaggatg atgtcttcac gtttgcgaat
     4561 ttcttccatg agtttttgca tgcgttcttc aaattgtcct cgaatccccg ttccttgaac
     4621 taagctaacc acatccagac ggatgacttg tttaccttgg agtttatgtg gcacatcgcc
     4681 atcgacaatt ttctgagcta gaccttcgac aacggccgtt tttccgacac caggttcacc
     4741 gataaggaca ggattattct tggttctacg attgagaatc tcgatgacac ggataatctc
     4801 atcgtcgcgc ccaataacgg ggtcaatgtc tccacgacgg gcaatttcag ttacattaat
     4861 accaaattct tccagcaggc ctttttcttg gctaggtggc ggagtttgag cagatccacg
     4921 attttgggaa ccataaccgc cgtttccacc gtaacctcca cctgattggg ttgggggaat
     4981 aggaggagta ttgctagaag gtctgaaatt gtttagatca ttgaagaaat caccaaaggg
     5041 atcgaagtca cgattgttca gatccgtcat acctttgaag aggctattgt taggatctgt
     5101 tttgataatc ttatagcagt tttgacagag gtcaatttgt ttttgttttc cattgagatt
     5161 ggtgtaaaga tgaattgttg agtcgttaat tttacagttt tgacaaagca tacatctacc
     5221 tcatttcttt ctttagcctg acttgtttaa aggtcaaaaa tagtcaaatt ctatactctc
     5281 attataacag gattggggtg taaagcaagt aaaaagattg aagctttgag aagttgttac
     5341 aatgaaaatt tttgtgaatt tggactataa aaaaatccta tttgtgagac aaaaaggatt
     5401 ttacttagac atgcagggac aatcccagct tgttttagat tagtagagaa gttcgtaaat
     5461 ttccattgcg attaagtcaa tgctatcaaa cgtatacgtt tcgcgatctt ctacgtcacg
     5521 aagggtaaag attgggccgt tttcttcgtc gtggctgtac gcaacttctg caacaacaac
     5581 tccttcgcgt tcaaaattac gttttaaatt tccgccatcg tttgccattg cttcaaggcg
     5641 gttgatgatt ctaaccaaat gtgattccat tttgattctc cttcatttct tatcgttact
     5701 attttaccat aaaggaggcc aacttgacta gaaaaaacta agatttctcg ttaattctgc
     5761 tagtttaaag atttttaaat aaattggata aaaaatttaa attttaattc aaaacatgtt
     5821 ataatcatac agtattctat tttagaaagc agtgtgacta tgaatttttc ttttttacct
     5881 aagtatttac cttattttaa ctatggggct gttgtgacga ttcttatttc tatctgtgtt
     5941 atctttttgg gaactatttt gggtgttgtc ttggcttttg ggcaacgttc aaagtttaaa
     6001 ccgcttgttt ggttggccaa cttgtacgtt tggattttcc gtgggacacc gatgatggtt
     6061 caaattatga ttgcctttgc tcttatgcat atcaatgctc cgactattca gattggaatt
     6121 ttaggtgttg atttttcgcg tctgattcca gggattttga ttatctctat gaatagtggt
     6181 gcttatgttt cggagactgt tcgtgccgga atcaatgcgg ttccaaaagg tcagctagag
     6241 gcggcttatt cgctagggat tcgtcctaaa aatgcgatgc gttatgtgat tttgccacaa
     6301 gcagtcaaaa atatcttgcc agcattgggg aacgaattta tcaccattat caaggacagc
     6361 tccctcttat cagctattgg ggtcatggag ttgtggaatg gggctacaac agtttctaca
     6421 acaacctatc tacctttaac accactttta tttgcagcat tttactactt gattatgacc
     6481 tctattctga cagtagcctt gaaagctttt gaaaaacata tgggacaagg agataagaaa
     6541 taatgacaga aaccttgata aaaattgaaa atttacataa atcttttgga aagaatgaag
     6601 tattgaaggg catcaacctc gagattaaaa gaggagaagt tgtcgttatc atcggtcctt
     6661 cagggagtgg gaaatctacc ttgcttcgct ctatgaattt gttggaggaa gcaaccaagg
     6721 ggaagcttat ctttgaggga gtcgatatta cggacaagaa gaatgacctg tttgccatgc
     6781 gtgagaagat gggcatggtt ttccaacaat ttaacctctt tcctaatatg actgtgatgg
     6841 aaaatattac cttgtcacct atcaagacta aaggtgaaag cagggaagtt gctgagaaga
     6901 gagcccaaga gcttttggaa aaagttggtt tgccagataa ggcagacgct tatccacaga
     6961 gtctgtcggg tgggcaacaa caacggattg ccatcgcgcg tgggttggct atggaaccag
     7021 atgttttgct ctttgacgaa ccaacttcag ccttggatcc tgaaatggta ggtgaggtat
     7081 tggctgttat gcaagacctt gccaagtcag gaatgactat ggttatcgta acacatgaga
     7141 tgggatttgc ccgtgaggtg gcagatcgtg ttatctttat ggcagacggt gtggttgttg
     7201 aagatgggac acctgagcag atttttgaac aaacccaaga acaacggact aaagatttct
     7261 tgagtaaggt tttataatct attttaaaat ttcaagacaa gattagtgaa aagttcaacc
     7321 agagcttttt cttatagttt gaaactatag gataacctag gaaagaagtg ttagagggca
     7381 ctagcagttt ttggtataat ggaagatatt tgaaagaaaa gagaagtgat atgacacaga
     7441 ttattgatgg gaaagcttta gcggccaaat tgcaggggca gttggctgaa aagactgcaa
     7501 aattaaagga agaaacagct ctagtgcctg gtttggtagt gattttggtt ggggataatc
     7561 cagccagcca agtctacgtt cgcaacaagg agaggtcagc tcttgcagct ggttcccgta
     7621 gcgaagtagt gcgagttcca gagactatta ctcaagagga attgttagac ctgattgcta
     7681 aatataatca ggatccagct tggcatggga ttttggtcca gttgccatta ccaaaacata
     7741 tcgatgaaga ggcggtttta ttagccattg atccagaaaa ggatgtggat ggtttccatc
     7801 ccctaaacat gggacgtctt tggtctggac atccagtcat gattccctcg acacctgcag
     7861 gaattatgga aatgtttcat gaatatggga ttgacttgga aggtaaaaat gcggtcgtaa
     7921 tcggtcgttc aaatatcgtt ggaaaaccta tggctcagct tcttttggct aaaaatgcga
     7981 cagtaacctt ggcccactca cgaactcata atcttgccaa ggtggctgct aaagcagata
     8041 ttcttgtagt cgcaatcggc cgcgccaagt ttgtgactgc tgactttgtc aaaccaggtg
     8101 cggttgtcat tgacgttggg atgaatcgag atgaaaatgg gaagctctgt ggagatgttg
     8161 attatgaggc agttgcacca cttgctagct atatcacgcc agtccctgga ggtgtcggtc
     8221 ctatgaccat taccatgctg atggagcaaa cttatcaagc agcacttcgg acattggata
     8281 gaaaataaga gaagcattcg attaatagag tgtattttct atagctatat ctaaaatggc
     8341 agaaatgaat attaaatttt agatataaga ttacaaaagg aggtctgcgt ctccttttta
     8401 ttgtataata aaagtgagag gaaaaaagga tgaaagtgat taatcaaacc ttattagaaa
     8461 aagttattat tgaacgttct cgttcaagtc ataaaggaga ttatggtcgt ctgctgctgc
     8521 ttggtggtac ttatccttat ggaggtgcca tcatcatggc tgctttagca gctgtaaaaa
     8581 gcggtgcagg attggtgacc gttggaacgg acagggaaaa tatccctgct ctgcacagtc
     8641 atttacctga ggctatggcc tttgctcttc aagacaagca attgttaaaa gagcagttgg
     8701 agaaggcaga agttgttttg ctgggacctg gtttaggaga caatgctttt ggagaagatt
     8761 tagttaaaca ggtctttgct ggcttaaaac agaatcagat tttgattgta gacggaggtg
     8821 ctttgactat tcttgctagg acaagtctgt catttccttc tagccagctt atcctaactc
     8881 cccaccaaaa ggagtgggaa aaactgtctg gaattacgat tgaaaagcaa aaggaagata
     8941 caacggctag tgccctgact tctttcccta aaggaacaat tttggtggag aaaggtccgg
     9001 ctactcgtgt ttggcaagct ggccagtctg attattacca gttacaggtt ggcggtccct
     9061 atcaggcaac tgggggaatg ggagatactc tggctgggat gatcgcagga tttgtaggcc
     9121 aattccgaca ggccagtctc tacgagcgtg tagcagtagc gacccatctt cattcagcca
     9181 tagcccaaga actatctcaa gaaaattatg tggtcttacc gacggaaatc agcaggtatc
     9241 ttcccaaaat aatgaaaatt atttgtcaac aagagagggt aagcaaagat aaacttgttt
     9301 aaaatagaca gataaatcta cttccttctc ttaatttatg attcttgaaa tgcgcctgct
     9361 ttaaggctaa actagacgta tcaaagttaa gagtttgttt ttgtaactgg aaagagatga
     9421 acaaatcaaa tacataaaag ataaactcat ttttattcgt ttggtaaaaa taaaatgcat
     9481 atttttaaag aaagattgat gaaaaatgta gatttgatgt ttttacttga ataaaaagcg
     9541 gtttcatagt aaaataagaa ctgagaatga tggaggtaaa tcggtggaaa atctgaagaa
     9601 aatggcaggt atcaaggctg ctgagttcgt gagcgatgga atggtcgttg gacttggaac
     9661 aggctcgact gcctattatt ttgtcgaaga aatcggtcgt cgtatcaagg aagaaggatt
     9721 acagattaca gctgtaacaa cttctagtgt gaccactaaa caggcagaag gccttaatat
     9781 cccgctcaag tctattgacc aagtagactt tgtcgatgtg acggttgatg gcgcggatga
     9841 agtggatagt cagtttaatg gaatcaaagg cggtggtggt gcccttctca tggaaaaggt
     9901 ggtcgcaaca ccatcaaaag aatacatttg ggtggtggat gaaagcaagc tggtcgaaaa
     9961 actaggtgct tttaaattgc cagtagaagt ggttcagtat ggtgcagagc aggtctttcg
    10021 tcattttgaa cgagctggct acaaaccaag tttccgtgaa aaagacggcc aacgttttgt
    10081 gacggatatg cagaatttta tcattgacct cgccttggat gtcattgaaa atccaattgc
    10141 ttttggacaa gaattggacc atgtcgttgg tgttgtggag catggtttat tcaaccaaat
    10201 ggtggataag gtaatcgttg ctggacgaga tggagttcag atttcaactt caaaaaaagg
    10261 aaaatagaag ggggcataag atgtctaaat ttaatcgtat tcatttggtg gtactggatt
    10321 ctgtaggaat cggtgcagca ccagatgcta ataactttgt caatgcaggg gttccagatg
    10381 gagcttctga cacactggga cacatttcaa aaacagttgg tttgaatgtc ccaaacatgg
    10441 ctaaaatagg tcttggaaat attcctcgtg aaactcctct taagactgta gcagctgaaa
    10501 gcaatccaac tggatatgca acaaaattag aggaagtatc tcttggtaag gatactatga
    10561 ctggacactg ggaaatcatg ggactcaaca ttactgagcc tttcgatact ttctggaacg
    10621 gattcccaga agaaatcctg acaaaaatcg aagaattctc aggacgcaag gttattcgtg
    10681 aagcaaacaa accttattca ggaacggctg ttatcgatga ttttggacca cgtcagatgg
    10741 aaactggaga gttgattatc tatacttcag ctgaccctgt tttgcagatt gctgcccacg
    10801 aagacattat tcctttggat gaattgtacc gtatctgtga atacgctcgt tcgattaccc
    10861 ttgagcgtcc tgcccttctt ggtcgcatca ttgctcgccc ttatgtaggt gaaccaggta
    10921 acttcactcg tacggcaaac cgtcgtgact tggctgtatc tccattttcc ccaactgttt
    10981 tggataaatt gaatgaggct ggtatcgata cttatgctgt gggtaaaatc aacgatatct
    11041 ttaacggcgc tggtatcaac catgacatgg gtcacaacaa gtcaaatagt catggaattg
    11101 atacactatt gaagactatg ggacttgctg agtttgaaaa aggattctca ttcacaaacc
    11161 tagttgactt tgatgccctt tacggccatc gtcgtaatgc tcacggttac cgtgattgct
    11221 tgcatgagtt tgatgaacgc ttacctgaaa ttatcgcagc tatgagagag aatgaccttc
    11281 tcttgattac tgcggaccat ggaaatgacc caacgtatgc aggaacggat cacactcggg
    11341 aatatattcc attgttggcc tatagtcctg cctttaaagg aaatggtctc attccagtag
    11401 gacattttgc agatatttca gcgactgttg ccgataactt tggtgtggaa actgctatga
    11461 ttggggaaag tttcttagat aaattggtat aagatgacgc gctatgcttt gctggtgaga
    11521 ggtatcaatg ttggtggtaa gaataaggtc gtcatggcgg agcttcgtca agaattgaca
    11581 aacttgggac tggaaaaggt tgagagctac atcaacagtg gcaatatttt ctttacttcg
    11641 atagattcca aagcccaatt ggttgaaaag ctagagactt tctttgcagt ccattatcca
    11701 tttattcaga gcttttcttt actgagtcta gaggactttg aggcggaact tgaaaatcta
    11761 ccagcttggt ggagcagaga cttggcacga aaagattttc tcttttacac tgagggtttg
    11821 gatgtggacc aagtcatcgc gacagttgaa agtttagagc tgaaagatga agtgctttat
    11881 tttggaaaac ttgggatttt ctgggggaaa ttttctgaag aatcctattc taagactgcc
    11941 tatcagaagt acttgctgaa ggtgcctttc taccgccaca ttactattcg taatgctaaa
    12001 acctttgaca aaattggtca aatgctaaaa aaataataaa ggagacacac aatgacattt
    12061 ttaaacaaaa tccatgaaac tgctactttc ctgaaagaaa agggaattgc agcccctgag
    12121 ttcggtctaa tccttgggtc aggacttgga gaattggcag aagaaatcga aaatccagtt
    12181 gtagtagact atgctgagat tccaaactgg ggccgttcaa cagtagtcgg tcatgctggt
    12241 aaattggtat atggtgaact ggcaggtcgc aaggtcttgg ctcttcaagg tcgtttccat
    12301 ttctatgaag ggaatcctct ggaagtggtg actttcccag ttcgtgtgat gaaagttctt
    12361 ggatgtgaag gtgttattgt aaccaatgca gctggcggta tcggatttgg tcctggtacc
    12421 ttgatggcta tctcagacca tatcaacatg acggggcaaa atccattgat gggtgaaaac
    12481 ttggatgact ttggcccacg tttcccagat atgtctaggg cctacacacc agaataccgt
    12541 gccactgccc atgaagtggc taaaaaactt aatatcaagc ttgatgaagg tgtctatatc
    12601 ggagttactg gtccgactta tgaaacacca gcagaaattc gttcctataa gacactggga
    12661 gcagatgcag ttggtatgtc tacggttcct gaagttatcg tggcagccca ctctggcttg
    12721 aaagttctgg gaatttcatg tatcactaac tttgcggctg gtttccaaga agaactcaat
    12781 cacgaagaag ttgtagaagt gactgaacgt gttaaaggtg atttcaaagg cttgcttaaa
    12841 gcgattcttg ctgaattgta agaaaaaaga tttaaaaggg ggagtgcctc tgtcttttca
    12901 ggattgactg cctatccgta ttaaagaaga aacagaggaa tactatgagc ttcttcctgc
    12961 tcttataact gaaagaagcg gaagaatagg tatgtctgat ctgatagcca gcattgtgaa
    13021 agacaagatt ctaggatact agcattagct tcctagccaa gcagactagt atgataagga
    13081 gagatgagaa tgaattgact ttctgaattt ctcagtctta tcatatatag cacaatgaga
    13141 tttcgcttga gtctgcttgt aaataaacga aaagaaagat aagaaataat gaaaattggt
    13201 caacgaatta tgcgctttgg cataaaaaat taagtatcgg agttgtatct gttgtagtcg
    13261 gctttgattt ctagctccag ctggaatttc agccaatgaa gtaaagcaag atgtaacatc
    13321 tgaagtggta ataggtgtgc tagattctaa ggaggaattg aaagagtcag aaaatgatgc
    13381 tccaaaacta gaaactcctc ttagagagga gccaagacta gctcctcaaa cgcttccgga
    13441 agcaagtgaa gttcttgaaa acaaaaggga agagtcaaaa gtagagataa cagagccagc
    13501 tcaagcggat gatatccgca aggttgttgg ggaattagcc aaggatataa gtattactaa
    13561 gttgtatatg acaggtcatt ctcttggagg ctacctagct cagattgcag aggttgaagc
    13621 ttaccaaaaa tatcctgatt tttataacca tgtattgagg aaagtgacaa ctttcagtgc
    13681 tcctaaagtg attacttcca gaactgtttg gaatgctaag aatggtttct gggatgttgg
    13741 tttggaaagt cgtaaattag ctgttagtgg aaaaattaag cattatgtgg ttgataatga
    13801 caatgttgtg actcccttga ttcataatga tcgtgatatt gttacattta caggtaattc
    13861 acgctttaaa caccgttctc gtggctattt tgaaagtcca atgaatgata ttcctaactt
    13921 taatattggt aaacaagcta ccttggataa acatggttat cgtgatccga aattggataa
    13981 agtgcgattc tttaagaaac aggctctgcc tcgatcttct agtcaaccaa gcgctgaacc
    14041 aatggaaaat attgccttag gaaaacaggt tactcaaagt tcgacagctt tcggaggaga
    14101 tgctagaaga gctgtggatg gcaaagtcga tggtaactat ggtcacaatt ctgtcactca
    14161 tacaaacttt caatctaagc cttggtggca agtagatttg gctaaagaag aaaccattcg
    14221 ccaaatcaat atttacaacc gaacagacac tgcccaggat agattggcaa actttgatgt
    14281 cattctttta gacagttctg gtaaagaaat tgagtgaaaa cgtataacat ctcctaaaga
    14341 tgtgtcagca caaattacga ttaaccataa aaaagcgcgc tatgttcgga ttgagctaga
    14401 aggctataat gccctcagtc ttgcagaagt tgaagttttc cgctttatag ctacgaatgg
    14461 tgaaacggcg atacaagttt ctaagtcagt tcaaccaatc agtcagactc ctgtgaagga
    14521 taaaacattg acaattcaac acagtggagc ttacattgcc cgctactcca taacttggga
    14581 agaagttaca gtagataaag atggaaacca agttgttcgt agtcattctt gggaaggaaa
    14641 cggtcgcaac cagactgcag gttttgtcct caacctccca atcaaagaaa atatgagaaa
    14701 tctgcgagtt aagattgaga aaaagacggg cctactatgg aatagatggc aaacaatcta
    14761 tgaaaacaga ccaattttag ctcaacccca ccgtaaaatt acccattggg gtacgacatt
    14821 gaattccaag gtgagtgacg atgatgtctt gtaatctgat ggtacaatga tagttagttt
    14881 gtctagttta taagaaagta ctacctgagc ttgaatagga ctcaggtagc tctctgtgaa
    14941 agaacaaaat t
//
LOCUS       DAVDHC010000046        14780 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVDHC010000046 DAVDHC010000000
VERSION     DAVDHC010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.046"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(393..1001)
                     /locus_tag="VUR43_001990"
     CDS             complement(393..1001)
                     /locus_tag="VUR43_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET5413622.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSFFFLPYIPLPIYIISILRH
                     IGVIYIILHLMATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            1167..1337
                     /locus_tag="VUR43_001991"
                     /pseudo
     CDS             1167..1337
                     /locus_tag="VUR43_001991"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            1326..1937
                     /locus_tag="VUR43_001992"
     CDS             1326..1937
                     /locus_tag="VUR43_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET5413623.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILIIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            2655..3341
                     /locus_tag="VUR43_001993"
     CDS             2655..3341
                     /locus_tag="VUR43_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET5413624.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMADISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            3342..4274
                     /locus_tag="VUR43_001994"
     CDS             3342..4274
                     /locus_tag="VUR43_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5413625.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            4285..5214
                     /locus_tag="VUR43_001995"
     CDS             4285..5214
                     /locus_tag="VUR43_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5413626.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPSAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            5228..6667
                     /locus_tag="VUR43_001996"
     CDS             5228..6667
                     /locus_tag="VUR43_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413627.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            6736..8313
                     /locus_tag="VUR43_001997"
     CDS             6736..8313
                     /locus_tag="VUR43_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET5413628.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            8373..9833
                     /locus_tag="VUR43_001998"
     CDS             8373..9833
                     /locus_tag="VUR43_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET5413629.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            9855..10310
                     /locus_tag="VUR43_001999"
     CDS             9855..10310
                     /locus_tag="VUR43_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET5413630.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            10815..11264
                     /locus_tag="VUR43_002000"
     CDS             10815..11264
                     /locus_tag="VUR43_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET5413631.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDISKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGEALFSIILKKNMLLLLEPNDAHKTGLLVEEPINIKKVVFKVKI"
     gene            complement(11376..11617)
                     /locus_tag="VUR43_002001"
                     /pseudo
     CDS             complement(11376..11617)
                     /locus_tag="VUR43_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            11788..12069
                     /locus_tag="VUR43_002002"
     CDS             11788..12069
                     /locus_tag="VUR43_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET5413632.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYMSFIAMV"
     gene            12201..13145
                     /gene="manA"
                     /locus_tag="VUR43_002003"
     CDS             12201..13145
                     /gene="manA"
                     /locus_tag="VUR43_002003"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET5413633.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEDELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGTGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(13185..14102)
                     /locus_tag="VUR43_002004"
                     /pseudo
     CDS             complement(13185..14102)
                     /locus_tag="VUR43_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            14141..14780
                     /locus_tag="VUR43_002005"
                     /pseudo
     CDS             14141..14780
                     /locus_tag="VUR43_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5156 a         2024 c         2807 g         4793 t
ORIGIN      
        1 aaggcgttta tgatatttag ctgtacgaga gtcttttaaa agtgttttga tggtttggat
       61 ttcttcttta gtcaatttca tatcactatt atataatgct ttttgatttt agtttagtat
      121 aaaactaaaa gtatatttga ttttttgaca atctaataaa attaagtaat taaataacgc
      181 ataagtcaag tattaaatac catgatctta tgcgttttat aataaaaaat ctgttcttgt
      241 tttattttta gaaaatttac taaagactaa aaatattgtg aataatttaa aaaatagtca
      301 ggttatatag ttttttgaaa ttaaaattat tttatcgttg aaattagtta aaaattttta
      361 taaaatcaag atgtaaggct atgagatgtt ctctagttta atttttcata cttcgagaat
      421 ataaagttat ataaaaatgc attagcatat tttgttattg agggaagtat aaaaatcatt
      481 aaagttatcc aaactagtaa ttgattctgt aatataaaga agagtagaac tgggataatt
      541 tcaataattc taataagaac ggcaataaaa aaatgtttat aggctaacat gattgaattg
      601 tgtagagaat tttttaaagt gttattatat ctaccgatta aaggaattag aaatgttgtt
      661 gccattaaat gaagtatgat atatattact ccaatgtgtc gtaagataga aatgatatat
      721 ataggtaatg gtatgtaggg taggaagaaa aaactgaata ataagattaa aattggtaaa
      781 ttagatatta atgctgctcc taaatttttc caataatctt taaaaaaact gtttgcgaag
      841 tctctatagg gataggattc ctcgtgtcgt acaattttta ttagagttgc tattagggca
      901 ctttcacctg atccgatagc aataactgtt actactgacg ctacatagag tagatttaac
      961 attataagat ttgaaacttt atcaataaat tttatctgca tctttaactc ctgctgtttt
     1021 tatacttata atatcacatc atttgagttt catcaacttt gaatacatta agaaagaata
     1081 taactatgag gaaaggaaaa aattattatg aataaatcca aaaaatataa agaaagaatt
     1141 cattctgaat acgataatct tactaaatca gagaaaaaat tgctgactat attttagtta
     1201 gagatagtga aatagtttat gaaacgtctt cagaaattgt tagtaaagta aaagttggag
     1261 agggaactct taatcgattt tgcaaaaaga ttggatactc tggttttcag gaactaaaat
     1321 taaaaatgac gaaagatata ttagagttag aatctcaaaa aatgagtagt gacacattta
     1381 ttgatgaaat aaaaaataat tatttatcta ttgtggaaag tacaagaaaa ttaattgatg
     1441 gtagacaaat agaattagct ataaaattaa taagagaagc aaaccagatt ttaattattg
     1501 gtgtgggttc tagtggaaat gcggctagag aatttgagag tagtttgtta agaattggaa
     1561 taataagtaa gacggtaatt gatacccatt ttcaactcat gcatactgcg ttattgaaag
     1621 ataatgattt gataatagcg tttagtttat ctggttccac aaaagaagtt gaggaaactt
     1681 tattaaacgc aaaaagaaaa aatgttaaaa ttatttcaat aacaaattat tcgtccagaa
     1741 atatagcaaa attatctgac tgcgttcttt tgacatcaaa aaaagaatct tatttagagg
     1801 gtggtagttt aatggctaag gcttctcaac tattcataat tgatgtaata tgcactagac
     1861 tctctttaat aaattatgaa gatactatat gtaaaaaaga agagattgct tctttgctgt
     1921 caaataaagt ggaataaatc aataattttt aaattttaat aaaaattttt taaaataaat
     1981 taaaaaacga tcctaaaagg gtcgtttttt tgctaaagtt ttaaaaataa acaataatta
     2041 agattatagt gcgttgaatc tatattagga cataacaatt cttaaatcat tgttagaaat
     2101 tagtttgaat tttccaatca atttgttcga tttttacatc attgcattat atcatgtgac
     2161 tattaacctt gttttctcct aaaattgatt ttcttctttt cttatcttgt ccactcgaaa
     2221 caagtattgt aagaatttga ttatttttga aagtactttt aatatatttg agatagttaa
     2281 aaaagatttg aaactaaatt ccaaattaga aaaagacttg aaatactaaa aaaaaaaaag
     2341 tatactctaa ttgaaaacgg taacaaaact aatttagaga atgaaatata gagtatttct
     2401 ctcttaaaag tttttggtga aacgagatgt agaagggaga tttagccaaa gagtctatta
     2461 gtgctagaat aatagattag aattatagtg tattgaatct ataacagtac gccttaaatg
     2521 ctaaaatatt tctataaatt aatttaactt tcctgatagg gctgttcata tcttatttca
     2581 attcactata taaataaaat tgtagtagat gttattgaat tagtaaaaaa aataaaaaaa
     2641 cggaggtttt ctgaatggaa actaaaaaaa ttaaaaattt aaaaggtcaa ataattgttt
     2701 cctgccaagc gttagaagga gagccacttt atactccaaa tggaggagtg atgccgttat
     2761 tagcaaaagc cgcctttcaa gcaggcgcta aaggtattcg tgctaattct gtccgcgata
     2821 tttcagaaat aaaagaagaa gttgacttac caattatagg tatcataaaa agagattacg
     2881 atggctttga accttttatt tcagcaacta tgaaagagat tgatgaatta gttagtgaag
     2941 gagtagacat tttagctttg gattgtacta atcgttcaag accaggttat gataatatta
     3001 ctgactttat tcatgatatt aaagtcaagt atccaaacca attattaatg gctgatattt
     3061 ctacttttga agaagggaaa gtagctgctg aatcgggagt agattttgtg ggtacgacat
     3121 tatctggtta tacaccatat agccctaaaa aagataatcc tgattttgag ttagttgaaa
     3181 gattggtaaa agagcttgac gtaccagtta ttgctgaagg aagaataagt actccggaac
     3241 aagctagaaa aatgttagat ttaggtgctt acgcagtggt tgttggagga gctatcactc
     3301 gtcctttgga aatagcgaag aagtttattg aggtagttta gatgaatcaa gaaatattaa
     3361 aaaagagtaa gattcaattg acagttgaac atattcaaaa atattggatt ttatatttaa
     3421 tgatgattcc agcaactgtt ctactaattt tatttacgta tggaccaatg tacggcatta
     3481 ttatggcctt tcaagacttt actgtcttca agggatatac tggaagtcca tttgtcggtt
     3541 taaaacattt tcaaagattg ttctcagatc ctttgtttta tagattgttc aagaatacgt
     3601 tcatggtagg ggttttagac tttttattct ctttcccagc tccgcttatt tttgcactca
     3661 tattaaacga agtcagaaaa gtaagattta agagtgtagt tcaatctatt agttatcttc
     3721 ctcattttat tcccctagtg gttatggttg gtattatttt tgaactattt ggttcatatg
     3781 gtattattaa cagtttactt tcatcacttg gaatggagcc aataagtttc tttacaaaat
     3841 ctgaatggtt cttgcctctc tacattggtt caggagtatg gaaaacaata ggttggggtt
     3901 ctatcattta tatgggagca ttaaccaata tagattcaac tttatatgaa gcagcagata
     3961 tggacggggc taatagatgg cacaaaatgt ggcatgtaac tctaccaagt ttaagaccta
     4021 cagtagttac tttgtttata ctaaatgctg gtggtatcat gcaagtagga tttgaaaagg
     4081 tattcttgat gtctagtcct gcaacatatg aagtatctga tgtattatct acttatgttt
     4141 atagacaagg tattttaaat tctgatttca gttactcagc tgcagtagga ttatttaata
     4201 acatagtagc tttgttattt gttttattag ctaataagat tgctaaaaaa cttggcgaag
     4261 aaggaattgt ataagggggg taaaatgatt ttttcaaaaa atacaaaaaa gagtaataga
     4321 gacaaagaaa ccttcgttga ttatctcttt atattcattt taataataat aaccttactt
     4381 atgttgtatc cattatggtg ggtagtgatg acgtcacttt cagaaccagt ttggctatct
     4441 aaaaacgttg ttaaattatt tcccttaaaa atagatatta ctgcatataa gtttattttt
     4501 ggggattcta aactatggca agcatatggt aatagtgtat tgtatgctgc actatctaca
     4561 attgttagtg ttgcggtatg tagtatgtat gcctatccac ttacaattcc tgaaattagg
     4621 ggtaaaaaat tctggaatac tcttattttg attccaatgt tctttagtgg aggaatgatc
     4681 ccgctttata tacaagttgc aaacctcggt ttattgaata ctgcttgggc tcttgtttta
     4741 cctagtgctg tttctacata ttatataatt ttgtttagaa cacagtttaa atcaatccca
     4801 atggagcttc gtgagtctgc tagaattgat ggggcaagtg aatttagaat tttttggaat
     4861 ttagtattac cattatcaaa agttattttc atgattatag cactttattg catagttggt
     4921 tcatggaata gttttactcc tccattactt tatttgaatg acgacactaa gatgccttta
     4981 tctatttatt tgagaaattt agttgttaca aatacaactg atactgctga attatcactt
     5041 tctgcaggta atacatatta ccaacaaatt gctgctcaag gtggaggtat tggtatgcgt
     5101 attgctatta agatgggtac tattgttgtt agtgttattc caattatgat gatttatcca
     5161 tttattcaga aacattttgt taagggaatc ctgctaggtt ctgtgaaagg ttaataaggt
     5221 aattattttg caaaatttaa aaaaatatct tttattagat agcggtttag tagttgggta
     5281 tacattagaa aatgctcaat taaaattaaa taagctaaaa aaagatactg aaaacaatcc
     5341 actatttggt gaagagtatt ttgccgaaaa tcctaaatta tgggaagttc gttttgataa
     5401 ttcatatcca aacgttatct atgataaaga attgaaatta tatagatgtt ggtatcaaac
     5461 atttgttagt gatgaagcaa gcgaagagac tcctttagca gaacgtggag agaaggaata
     5521 cattgtcaag tcatctagaa tgacagcact ttgctatgct gaaagtaaag atggagtaaa
     5581 atgggaaaaa ccaaatctca atctagtaaa atttaaaggt tcaaaagata ataatattgt
     5641 tctgatgcat gcacacggtg caggtatcat gctagatgaa caggagttgg atcctaagaa
     5701 acgatataaa ttagtttcaa aattagaatt ttctccgaat cttcattaca tggttgttgt
     5761 tttttcagaa gacggtattc attttgacga acctattcca tggaaaaaat ggaatcctgc
     5821 agcagatagt cataattttc catttagaga tccaaaaact ggtaaatacg ctgttattac
     5881 aagaacctgg gcaaataacg tacgtctaag tgcaattact ttcagtgatg attttattaa
     5941 ttggtcagaa cctaaagaaa tccttagggg agatggattt gaagatcaaa tttattctat
     6001 gccagtaatt tcatacgcgg atatctattt aggttttgct tcaatgtacc acgaaggcga
     6061 cactttaaat gaaaactatg ataaagtaga cttagaattg aaattctctg ctaatttgga
     6121 acaatgggat agtgtatgta agggcgacta tctcattgaa aggggaggtg gagtataccc
     6181 gcagaatgct gattttgatg ctagttgtat tttcacggct gctccaataa ttgaagatga
     6241 taagatttgg ttctactata tgggtggaaa tggtaatcac actggcttcc gagaaagttc
     6301 attagctaga ggatatatta agaaagacca atttgcttat tatactaata agagagaagg
     6361 aattccagct aaaatatcta cagttagctt ccaaacttac gatgatgaaa tttatatctt
     6421 agctgatatt cctgaaaatg gttatattaa agttgcggta ggtactaaat acggtaatgc
     6481 ttattcagat tttggtcagg aagatatctc tcttgttcaa gtttccgatg gtaagtataa
     6541 gttggaattt aataaaaaat ctatcttaga tttaggtaat tctccagttg cgttcaaatt
     6601 tgaaatcgag aatgcaaaat tgtatggtat tgaaggtagt attcagcaac actatctcaa
     6661 atattaacca gaataattcg ttaacaaata atctctatat tagtggagat agatatataa
     6721 aatggaggtc ttattatggt aaagcttaat aaggtattaa aagggagtgt tgcattcctg
     6781 agtgcaagtt tattgctagc agcttgtggc aataacgcta attcaaagcc cgctgaaaaa
     6841 acagctgatg gtaaaacgaa aatttcgttt ctatctacat ggcaaattaa tgatgttcgt
     6901 ccgcctaaag atgaaacact tgttggtcaa tggttagaag aacagctagg tattgatatt
     6961 gatcttgtaa ctattcctgg cgagggagta agttctaaag taaattctct tattactagt
     7021 aaccagttac cgactgtttt gttgacaaca ggagataaga gtgatatcgc tggtatcaac
     7081 aaacttggta aacagggtgc attcttagat ttgtcacaac acatggacaa actaccaaac
     7141 tataagaagt accttgaaaa aaataatgca ttagctcaaa tagaagatga tgaaaaacat
     7201 atttatgctt tcacaaaatt ctttactgat gagaatatca tgtatactac accaattctg
     7261 agaaaagact tacttgttgg ttcagaattt gaagatcttt caaaaattaa aactgttgat
     7321 gactatacaa aagttttgaa atatttgact gaaaaacaag gttctccagc atttattcaa
     7381 cgtaatggct atgaaggctt catgaagcga gttacaccat tgtggaattt aagccatcgt
     7441 acatactatg actatgaatc agattcatat aaacatccag ttgaacaacc tcaattgaaa
     7501 caattcgttg aatggttgaa agaattacgt aaagataacg tacttcaccc tgactgggca
     7561 gttatgaaag atgaaacttg ggaaggtcta ttggcttcta acaagggttc attcactgtt
     7621 gaccgtatga atatcattgg agataataac tttgataaat catttgattg gcagccactt
     7681 gtttatccag aaattaatgg aaaacgttat ttgcaaccga aaacaccgta catttctgat
     7741 tcaggttggg taatcaatgc caatgcacca aaagaagaaa ttgataaagc gttagaattc
     7801 tttaatttct tatacgctga tgaaaatcaa gaaaaacttg ctattggatt tgaaggtaaa
     7861 acatttacac gtgaaaaccc taatactcaa gcaggtatta aatggttgat tcaaatttac
     7921 ggtgaaaatg ctggaaatga taaagcagaa ctgctgttta aacatggtaa ccaagcattt
     7981 actcgcgttc aaactaaatt agatattgag gcacagccag gaacattccc taaagttatg
     8041 tatgatcaag tagataaaat taagaaagat ttaggtggtt ttagaccaga tactccggtt
     8101 ctttccttta caactgaaga attagatgtt ttaactaaat ctgaagcagg attaaatact
     8161 ttctttgatg aaaatattat taaattcatt gaaggacaaa gagatatgag tgagtgggat
     8221 tcatttatca atgaagctaa atctaaagac ttggataaag ttacaaaagt atataatgat
     8281 gcctacaaac gtgtcaaaga tagaatgaaa tagactaaat ggtagctctc tggtttttca
     8341 gagagctact actgcctgag ggggagtaag ctttgtatga tgtagtaatt ataggtgcag
     8401 gaagttcggg cgcattggct gcaattgctt cggggcgtct agggttaaaa acttgtctaa
     8461 tagagaaggg aagtagaatt ggtggagttc ctattaatac actaatgggg tcatttgcta
     8521 atctatattt tgatgattct ggtagagtaa atgcaagtaa aattgttggg gaattaatag
     8581 aacgtattat caaaaaaggt ggtactgtct ttaactctat ggaagaattg atgaatgtaa
     8641 atgattttta tcagattaca attccctatc aaccagaagt ttatgaatcg gttttaactg
     8701 atatgttgat tgagtctaaa gttgatattt tactaaatgt tgaagttaat aatattattt
     8761 atgatagtaa aaatattaaa agtcttgaaa ttttaagtaa tcaggaagtt aaattgattg
     8821 attctaaagt ttttattgat gctacaggga atgcaacaat tgcttctgct agtggagctg
     8881 atgtttatga aaaaaattct tcttacggtt gtttaatgag agttggagga gttgatatct
     8941 caaagactat agaacatatt gaaaaaacaa agcagtggaa ctatatagaa ggatataatc
     9001 agtggttaga agaagtatta gcaaatcgaa agtacagagc cactggagca gttttaaaag
     9061 atccagtttc ttatgatcat gcccctatgc tttcaaaaga cgaccatttt atgaatgatg
     9121 aaaaatggaa ttacattaaa gaaagatggg aaaaatttag atttatttac actttagaag
     9181 tatcactatt taggaatgaa ttaaaaaaag ctgtagaatc tggggatttt aattttgaaa
     9241 tttatcatga tgataaatct ggagtcacta tgaatggcga cggtataagc tatggttcat
     9301 ggggtcaaaa tgtagcatta attaatgttg caaaagcatt tggattcaat cccaaatata
     9361 tggaagatga atcacatgct aatattcttt ctagaaaata taatttaaca tttttatctt
     9421 ttcttaaaaa atatgtacca ggttttgaaa attcttttat ccttgatcag ggaactagag
     9481 ctactaacag atcatgtagg cacattgata attcatctat gatggacgaa attcttgatt
     9541 ttccaatgta tacatttaag actatgtata gctatcaaac tcctaaagaa ataacgtaca
     9601 aatcaattgt aggtggaaaa ttgaataatt tgtttgtaat aggtaaaggt gcttaccaat
     9661 ccgaaagttt tagatcacaa attagttgta tgttaatggg gatatcatca gcagcagcgg
     9721 caaaaactat tattgaagat aaaagcaata ctctaaacat taatagagat ttgtttaaat
     9781 cgaacttaga tatattattt acatgggagt tttctaattg gattactgat taacaaataa
     9841 taagggaata ttaaatgaat gatactaata aaaatcaata ctttgtttat gaatttgata
     9901 ctagctttgt agaaatgtct tattctcagt tttttgaagg atattgtatt cttttttcaa
     9961 aagaacccta tccttcttta tctgatatgc caatggaatt tagaaaagaa tttttaatgg
    10021 aaatgagtat attaggtgat gcgatgcttg aagtgttaaa tgcctataga attaattatg
    10081 atatcttagg aaattcaaca cctgtacttc atgctcattt atttccgaga tacatgtggg
    10141 aagaggaaga gagaagaaaa actgtagttc atagatatga ttcttcagtt tttagcaatc
    10201 ctgagtttga atttactata gaaaagcatg gaccaattat taaaaaactg aggtctgcta
    10261 ttgatagaca ttatagagag tatcaacaat tattagatga ttcaaactga actccacatt
    10321 ttcgattaga tttaatacct tgtatattac aactaggttg tggatgatat aattttttga
    10381 aaaatatatt ttaggaatga cttataaagc aattatatca gaggctatta aatcaatggc
    10441 caaagcttat gctccttatt cttattttaa ggttggagct gcgttagaaa ctgaagataa
    10501 aaattttttc ctggatgtaa tatagaaaat gttgcttttc tcctacttgc tgtgcagaac
    10561 gagtatattt ttacaaagct gtatttaaag gagaacgttc gttttcaaaa atatgtattg
    10621 taggcggaaa aaaaggtatt ttatcatctt ttatagcatc ttgcagggtg tcttgtcagg
    10681 taatgataga attttgtaat cttgattcat ttgtagttat attggctagt gatgttgata
    10741 attataaagt atataaactt aaagaactac taccagttag ttttaatcaa gaaaatttat
    10801 aacaggaggg aactatggaa ttagttgaat ttaaaaatgg acatgttaat acggttcatg
    10861 agcatatcgc aataacgaaa gtaaaagagt ttctaaataa tcatgatata tcaaaagata
    10921 aaggtggcat acataaaatt tctactgatt tcttttacaa tataattgat atggaaacta
    10981 caactgaaga gaatagaccg tgggaaagtc ataaggaata ttatgatgtc cattatctgt
    11041 taaatggaga agaaacaatt ttatataatt tcttgtctca aatggaattg tctgaatata
    11101 aagtagatga tgattggcaa caaatgaatg gggaagcttt atttagtatt atattaaaga
    11161 aaaatatgtt acttttgttg gaaccaaacg atgcacataa aacaggccta ttggttgaag
    11221 aaccaattaa tattaagaaa gttgttttta aggtaaaaat ttaactgaaa gtactttcag
    11281 ggattaagaa ttttaaaata tttaagaaat tgtattctaa agttctaaaa ttatagatat
    11341 ttaatttaaa gcttgttaaa atagaatagt aacactcatc tgctttcaaa aagcattcta
    11401 gtccatctcc gattaacgat ggactttatc acctccttct ccagtccttg tatgacatct
    11461 tggagttgat tcatgacatc ttccaaagtt cgaaaggctt tattcttaaa tccacgttta
    11521 tgaatctctt tccacacttg ttcgatgggt tcatctctgg tgtgtatgga ggaataaagg
    11581 taaaaccaat attagtcgga atctttataa gatttgccca tcagacgaaa tagaatgatt
    11641 tgaaggcatt tatgatattt agctgtacga gagtctttaa aaagtgtttt gatggtttgg
    11701 atttcttctt tagttgattt catatcacta ttatataatg ctttttgatt ttagtatagt
    11761 attatcgtag aaaatggact cggtgctatg gatacaccgg atgagaatgg ttatgtagca
    11821 gatgactatc ggattactta cttagaggcc cacatcaagg ccatgcgaga tgccatttac
    11881 aaagacgggg ttgacttgct tggttatacg acatggggct gtatcgatcc ggtttcagct
    11941 ggcacagggg aaatgaataa gcgctatggc tttatctatg tagatcgaga taatgtagga
    12001 aacggagctc tcaaacgtag caagaagaag tccttctatt ggtacatgtc atttatagca
    12061 atggtgtaag catcgagtag agcacatttg tttactattt ttataaaatc ttctccctgc
    12121 tttataagat gtaaaaaaga gttcaaatgg aactcttttt ttgctataat gaggggagaa
    12181 aaatcagaca ggagattaag atgtcagaac cattattttt acaatcagtt atgcaagaaa
    12241 aaatctgggg tggtaccaag ctacgtgatg agtttggcta cgacatccca agtgaaaaag
    12301 tcggagagta ctgggctatc tcagctcatc taaatggtgt ttctaaagtt gccaatggtc
    12361 gttacgaggg aacagatctt gctactttgt atgcggaaca ccgtgaatta tttggcaatc
    12421 gtccagaacc tgtatttcca cttttgacca agatcctcga tgccaacgac tggctcagtg
    12481 tccaagttca cccagacgat gcttatggac tcgagcatga agacgaactt ggaaaaacag
    12541 aatgttggta catcattgca gcagatgaag gttcagagat tatctacggt cacaatgcca
    12601 agtcaaaaga agaactccgc cagcaaatcg aggacaagaa ctgggatgac ttgttgacca
    12661 aagtccctgt taaggctgga gatttcttct atgtaccaag tggcaccatg catgctatcg
    12721 gtactggcat cttgattctt gaaacccaac agtctagtga tacaacttac cgcgtctatg
    12781 actttgaccg aaaggacgat aagggcaact tgcgtgaact tcaccttgaa aaatccatcg
    12841 atgttttgaa cattggcgag ccagcaaata gccgtcctgt aactgttaaa gcagataatt
    12901 tgcgttccac tttacttgtt tctaatgatt tcttcgcagt ttacaagtgg gaaatcactg
    12961 gaaaagttga ttttgagaag acagctgact acagcttgtt gagtgtcttg gctggtcaag
    13021 gtcaactaac tgttgacggg aaaaactatc caatccaaaa agggagacac tttatcctac
    13081 caagtgatgt tgaatcttgg actctagaag ggcaagattt agaattaatt gttagtcatc
    13141 cataaaaaag aaaggacctg agttcattac tcaagtcctt ttgattacat aaattgggcg
    13201 atgaagacca cgatgatgat tggaatgacg aaacgaagaa ggaagagcca gacttggaac
    13261 agtccttgtt tccatgctct ttcatcgaga tggagttcct ccattgcaag agccttttta
    13321 aagatatagc ctgtaaaaag tgaaaggaag agagctccaa atggcatgag gagattggaa
    13381 accaagaagt ccatagcgtc aaagaaggct ttaccaaaaa tgtgaacatc cgccatgaca
    13441 ccgtaagata gggctgaagg aatgccaaag acaaaggtca aaattcctaa aataacactc
    13501 catttagcac gcttgctgtt gtcctgattg gtgatattgt ctacattgat ttccagcata
    13561 acgacagaag aagtgacagt cgcaaagagg aagaggacat agaaaatggt tccaaaaggc
    13621 atcttgtcaa agagttgagg caagacgata aagaccaagc tcggtccccc ttcagactgg
    13681 atattgaagg gggaccgagc ttggaaaatg gctagacctg ccatgatgga taccgagata
    13741 ttcatggcta cgatggagat tcttgactgg accagattgg ttttcttgtc caagtaagaa
    13801 gcataggtca acatggctgt aacccctagt gagagggcaa agaaagattg tctcagagca
    13861 tagaggagac cagcgctagt cagttttgaa aaatctggtt tgaggaagta aagaacccct
    13921 tccatggcat ttggcaaact gagagagcgt tcgatgatga cgacaaagat gataaagagc
    13981 aggggcatca tgactttcga agctctttca atcccttttt gaaccccacg tgatacaatg
    14041 aagatattca ataggataaa ggtcgcttga gctcctagag caatggctgg atttgaaatg
    14101 atcagacttc ctgcgaaaca aaatatggca tagtagttct atgaatgatg aagcaagtaa
    14161 acaactaact gatgcacgat ttaagcgtct tgttggtgtt cagcgcacga cttttaaaga
    14221 gatgttagct gtattaaaaa cagcttatca acttaaacac gcaaaaggtg gacgaaaacc
    14281 taaattaagc ctagaagacc ttcttatggc cactcttcaa tatgtgcgag aatatcgaac
    14341 ttatgaagaa attgcggctg attttggtat ccacgaaagc aacttactcc gtcggagcca
    14401 atgggttgaa gtaactcttg ttcaaaggtg gtgttacgat ttcaagaact cctctcagtt
    14461 ctgaggacac ggtaatgatt gatgcgacgg aagtaaaaat caatcgacct aaaaaaagaa
    14521 ttagcgaatt attctggtaa aaagaaatgc cacgctatga aggctcaagc gattgtcaca
    14581 agtcaaggga gattgtttct ttggatatca ctgtgaacta ttgtcatgat atgaagttgt
    14641 tcaaaatgag tcgcagaaat atcggacaag ctggtaaaat cttggctgac agtggttatc
    14701 aagggcccat gaagatatat cctcaagcac aaactccacg taaatccagc aaactcaagc
    14761 cgctaacagt tgaagataaa
//
LOCUS       DAVDHC010000047        13494 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVDHC010000047 DAVDHC010000000
VERSION     DAVDHC010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.047"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(74..1063)
                     /locus_tag="VUR43_002006"
     CDS             complement(74..1063)
                     /locus_tag="VUR43_002006"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET5413634.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEITEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(1127..2812)
                     /gene="lpdA"
                     /locus_tag="VUR43_002007"
     CDS             complement(1127..2812)
                     /gene="lpdA"
                     /locus_tag="VUR43_002007"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET5413635.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDCIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            complement(2876..3919)
                     /locus_tag="VUR43_002008"
     CDS             complement(2876..3919)
                     /locus_tag="VUR43_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET5413636.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            complement(4137..5129)
                     /locus_tag="VUR43_002009"
     CDS             complement(4137..5129)
                     /locus_tag="VUR43_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET5413637.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            complement(5145..6113)
                     /locus_tag="VUR43_002010"
     CDS             complement(5145..6113)
                     /locus_tag="VUR43_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET5413638.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            complement(6267..7628)
                     /gene="pdrM"
                     /locus_tag="VUR43_002011"
     CDS             complement(6267..7628)
                     /gene="pdrM"
                     /locus_tag="VUR43_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET5413639.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            complement(7639..7899)
                     /locus_tag="VUR43_002012"
     CDS             complement(7639..7899)
                     /locus_tag="VUR43_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413640.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            complement(7913..9181)
                     /locus_tag="VUR43_002013"
     CDS             complement(7913..9181)
                     /locus_tag="VUR43_002013"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET5413641.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGHVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            complement(9194..9658)
                     /locus_tag="VUR43_002014"
     CDS             complement(9194..9658)
                     /locus_tag="VUR43_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET5413642.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGM
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            complement(9668..10321)
                     /locus_tag="VUR43_002015"
     CDS             complement(9668..10321)
                     /locus_tag="VUR43_002015"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET5413643.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANTFLKETGQEPIDWLR"
     gene            complement(10457..11104)
                     /locus_tag="VUR43_002016"
     CDS             complement(10457..11104)
                     /locus_tag="VUR43_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413644.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            complement(11118..11831)
                     /locus_tag="VUR43_002017"
     CDS             complement(11118..11831)
                     /locus_tag="VUR43_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET5413645.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(12227..12451)
                     /locus_tag="VUR43_002018"
     CDS             complement(12227..12451)
                     /locus_tag="VUR43_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET5413646.1"
                     /translation="MESIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGGIG
                     TSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            complement(12874..>13494)
                     /gene="phtB"
                     /locus_tag="VUR43_002019"
     CDS             complement(12874..>13494)
                     /gene="phtB"
                     /locus_tag="VUR43_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET5413647.1"
                     /translation="LDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPK
                     GYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPSEEKPQT
                     EKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQVETEKVEEKLREAEDLLGK
                     IQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT         3942 a         2974 c         2453 g         4125 t
ORIGIN      
        1 attttacgta ttttaaatta tgtaaataaa tatcaaaaaa agaagttggt tagttggcca
       61 acttcttttt gatttatcca actaccgctt cagcgatttc ttcacggcta ataccagcga
      121 agtagcgtgt gatatcaatg gtttttagcg ccttaagaac atcttcacgt tcgtatttca
      181 ccccacgaag gacatcttct actgcagcaa cgtcttcaat accaaagaag tcaccataaa
      241 tcttgatgtc ttggattttt gattcagtaa cgttagcaaa gacttcaacc ttaccactag
      301 tgaatttggt tccacgacgg acgttaaatt caggtgattt accatagttc cagtcccaag
      361 ttccaaactt agtatccttg atgtgattga tttcggccaa ttcttcttct gaaaagacgt
      421 attcagtaat ctctgggtac tcttttttca tgtattccaa gagtaaatca cggaattttt
      481 cgactgtgat tttttttggt aattcattga taatattggt tacacgggca cggacggatt
      541 tcacaccttt tgattcaaat ttatcttttg aaaccttaag ggcatttgcg aggactgaca
      601 aatcaacgtc aaagagcaag caaccgtggt gcatgatacg gccgttgata taggcttggg
      661 cattgccaca gaacttctta ccatcaatct caaggtcatt acgacctgtg aactcagctt
      721 taaccccaag ttgagccagg gtattgataa ccggagttga gaagctcttg aagtcaaatg
      781 ccttattttc atcttctttg gagatgatcg tgtagttgag gttatttaaa tcgtggtaaa
      841 cagctccacc accactaata cggcgaacta cctcaatacc attttcgcga acataatcac
      901 ggttgatttc ttcgatagtg ttctggtgac gaccaacaat gatagatggc ttgttaatcc
      961 aaagtaggaa gatttgatcc tcatccaaaa ggtgtttaaa ggcgtattct tccaaggcaa
     1021 tattaaaagc agtgtcattt gaatgattga taatgtattt catgatatcc ctttacttta
     1081 tatgatagaa actggaaata accttccagt ctaatctatc ttcgttttat tttttcttag
     1141 gtgaatggat ggccattcct agaacatctg caaacgcttc gtacatcact tcagagtaag
     1201 ttgggtgccc gtggatggtc ttcagcattt cctcaacagt gatttccatt tcgatgatgc
     1261 ttgatgcttc gtttattaat tctgcggctg caggaccaat aatgtgtaca ccaaggattt
     1321 ctccgtattt cttatcagcg ataactttta cgaaaccttg agcagcgtca gatgcaatag
     1381 cacgaccgtt agcagcaaag ttaaacttac cgatggcaac atcgtatttc tcacgggctt
     1441 gttcttctgt caaacctact gctgctactt cagggagagt gtagatggct gcaggagtca
     1501 aattcaattt ggcaactgca tgatttcctt taagggcatt ttcagcggaa acttcaccca
     1561 tgcggaaagc tgcgtgagcc aacatcttag taccgttgat gtcacctggt gcataaatgc
     1621 ctggaactga agtttccatg tattcgttga ccttgataca accacgatcc aattcaaact
     1681 caacctctcc aataccttca aggtctggca tacgaccaat tgaaagaaga gctttgcttg
     1741 cgatgatatc gtcttttcct tcaaccttga tacgaagttg accattttcc tcaatgattt
     1801 cttgcagttt agtaccagtc aagatggtca ttcctttacg ctcaaggatc aagcgaaggt
     1861 tcttagaaac ttccgcatcc atagctggaa ctatacagtc catcatttcg ataacagtca
     1921 cttttgaacc aaatgtcatg aaggcctgac cgagttcgat accgacaact ccaccaccga
     1981 tgataacaag gctttctggc acttcgttca tttcaagaat gtcatcacta gtcatgacaa
     2041 gtggagattc cataccaggg acgttgatct tgctgacttt tgaaccacca gcaagaatga
     2101 ttttcttggt ttcaagcaat tcagagccat ttaccaagac gttcttgtct ttagtgattg
     2161 taccaattcc tttatgaaca gtaactccgt agctacgaag aagtcctgca acaccaccaa
     2221 caagagtatt aacaacttta gatttagttt ctaaaagttt ttccatatca acagtgaagt
     2281 taggattttc aatcacgata ccacgatttg cagcatgacc gatattttca ataatttcag
     2341 cgttatgaag gtaggtcttg gttggaatac atccacggtt taagcaggtt ccaccaagtt
     2401 cagatttctc aacaagggca accttaccgc cgaattgggc agctttaatg gctgcaacat
     2461 aaccagcagg acctccacca atcacaacga tatcaaaagc atcatcgctc ttatcatcat
     2521 cgtttgaggt acttgctaca ggtacagagc tagcttctgg cgatgctgct ccagctgttg
     2581 ggatgttttc cctttcttca ccaaggtaac cgataacttc cgttacaggg acagtttcac
     2641 catctccttt gagaatggca atcaagtacc catcttcttc ggcttccaat tccatgctga
     2701 ctttatcagt catgatttcc aaaaggattt ctccttcttt tacaaattct ccgacttttt
     2761 tattccattg gacgatttgt ccttctgtca tatccacgcc ggcttttggc ataattactt
     2821 ctaaggccat gtcttccttc ctttatctat atcttaaaaa tgaatactct tgctcttaaa
     2881 ttaacattga gattggcgtt tcaatcaact ctttcaagtc cttcataaac ttagcaccag
     2941 ccataccatc tacgacacgg tggtcaatgg ttaatcctaa actcatgatt gggcgaatca
     3001 caatttcacc attgacgaca actggcttct cgattgtcga actgacacca aggatagctg
     3061 agttgggttg gttaataatc ggaccaaagg actgaacacc aaacattccc aaattactga
     3121 ttgtgaatgt tgaattttgt aactcacttg gagccaattt accatccaag gtacggccaa
     3181 taacatcctt aaaggctaca accagttctg aaagactcat tttctcagca ttgtaaacaa
     3241 caggtgtcat caatccatta tccatcccaa ctgccatggc aagattgaca tagttgtgag
     3301 tgataatagt cttgccatct tctgtcaatg aagcgttgat gtatgggtgt ttcataagag
     3361 tcttaacaac tgcaagcgaa agaaggtctg ttacagtagt cttcttccca gttgcttcca
     3421 tgattggctc aagaaccttc ttacgaagag ccaacatttc agtcatatca acttcatagt
     3481 tgagggtgaa ggttggcgca gtcaagtaag attcaaccat gcgttgggca ataaccttac
     3541 gcattggtgt cattggaata cgctcgattt caccatatgg tgttacgtta tcagggactt
     3601 cttccacttt ttcaatctga gcaggagatt tgatgctatc gttttcgata ttttcaggaa
     3661 gcagggccaa aacatccttc ttcatgattt taccacgatg accggttcct tggatttcct
     3721 gccaagcaat gttatgttcg agggcaattc gttttgcaag tggcgaaatg cgaaccacgt
     3781 ttgtgtcttt ataagtttcc acgtcttctt tgtggacacg accgtttgca cctgagccag
     3841 aaacgtcgta gaggtttatc cctaaatcat ccgctaactt tctagctgca ggagtcgctc
     3901 ttagcttgtc atcagccatg acctctccaa ttctatttat gatacaaagg gcgtcaaaag
     3961 cgactgaaaa ataggaaatc gacgatggct tcgatgaagc caaggagatt tatctttttt
     4021 ccgagctttt agcccgtgct ctaatctaag atattaatga cgaagagctc tgcacctaaa
     4081 agatacaaag tttctcgtca gctttatttt atttacataa cttatcttat gtaactctat
     4141 tctttgttat aagtttttcg gattgcatct ttgatacttt caactgttgg aatcattgca
     4201 ttttctaggt tttgtgcata aggcatcggc acatcttctc ctgcacaacg gcgaattggt
     4261 gcatctagat agtcaaatgc ttctgattct gaaataatag ctgaaatttc accgatatag
     4321 ccacttgttt tgtgggcatc gttgaccaga acaaccttac cagtcttctt cactgagttt
     4381 atgatgatat ccttatcaag cggaacaagg gtacgtgggt caacaatttc aactgaaatt
     4441 ccttcttctg ctaattcttc agcagcttga accacacggc gaagcatttt tccataagta
     4501 acaactgtta catccgttcc ttggcgtttg atttcaccaa ccccaagtgg aattgtgtag
     4561 tctggatcaa ctggcacttc ccctttttgg ttaaattctg acttgtactc aagtataata
     4621 actgggttgt tatcacggat agaagactta agcaggcctt tcatgtccgc aggtgttcca
     4681 ggtgccacaa ccttaagtcc tggaatgtga gtaaaccaag actctagaga ttgtgagtgc
     4741 tgggcggcag agccaactcc gttaccagct gcacaacgaa cagtcattgg aacctgacct
     4801 ttaccaccaa acatgtaacg tgttttagca gcttggttga cgatattgtc catggcaata
     4861 acagagaagt ccatgaaggt catatcgacg attggacgaa gtcctgtcat ggctgctcct
     4921 gctgctgctc cagagatggc agcttcagaa atcggacagt cacggacacg ttctggacca
     4981 aattcttcaa gcattccaac agaagtaccg aagtctcctc cgaagacacc gacgtcttct
     5041 cccatcaaga acacattttc atcgcgacgc atttcctcag acatagcaag gataatggtg
     5101 tcacggaagg acattgtttt tgtttccatt ttatctcttt ctccttagtc tgcgtaaata
     5161 tcttcaaagg ctgattcaag cggtgggaat gggctttcct ctgcaaattt aacagaagct
     5221 tctactgctt cctttacttg cgcttggatt tcttccaatt cttcggcact tgcaatgtta
     5281 ttttcaataa ggtaattgcg gaggttttcg attggatctt tttgtttcca caattccact
     5341 tcttcacgcg tacgatattt accagggtca gatgatgagt gaccgagcca gcgataagtt
     5401 acactttcaa tcaagactga accattgcca ctgcgaacat ggtccacagc tttctgaaat
     5461 ccttcataga catcgatgac attgttacca tcttcgatga acattccagg aattccataa
     5521 gcggcgctac gttgatggat atgttctata ttggtcattt tcttgatatc cgcagagata
     5581 ccgtaaccgt tgttaatgca atagaaaatg actggcaggt tccagataga agccatgttc
     5641 actgcttcgt ggaaaacacc ttcattggtc gcaccatctc caaagaagca gacaacgatt
     5701 ttaccggtat tttgcatttg ctgactgagg gctgcaccga cagcgatccc cataccacca
     5761 cctacgatac cattggcacc aaggttccca gcatcaaggt cagcgatatg catagatcca
     5821 cctttccctt tacaggttcc agtgtattta ccaaggattt cagccatcat tccgttgagg
     5881 tcaatccctt tagcaatagc ttgcccgtgt ccacggtggt ttgaggtaat cagatcatct
     5941 ggattgagag ctaacatagc ccccacgtta gctgcctctt caccaacaga aaagtgcgtc
     6001 attcctggca ctttcccttt ctttactaat tgtgcaattt ttaagtccat gcgacggatt
     6061 tcttccatct tacggaacat ttctagcaaa agatttttat ctaaagttga catcttcttg
     6121 cctttctaac tttcttctta ccttactatt ttaccgcttt tggcaaatac tgtcaaagtt
     6181 tttctaaaag aaatttcaca aaataaaaaa gaaaaccccg tgaaaacaag ggattttctt
     6241 gtcaagaata ttttttcaca aactttttag cgtttggatt ttgctaaaga ttcaaatctc
     6301 ttcataatca cagttaaacg ccaacggtag agcgccccac tcacaatcaa actaataatc
     6361 aagccgatcc agtaagaata agctccaaaa tctgttaggg aatcaaatag cgtagccaca
     6421 gggattgcta cgccccaata accaagcaaa ccaaggtaaa aaggaataac tgtatcctta
     6481 tacccccgca aaattccctg aagcggcgcc gcaaaggtat ctgctaactg gaagaaaaga
     6541 ctataagtta aaaaacgcgc tgtcaaatcg ataaattttg ggtcgttacc ataaagactg
     6601 gccacatttc ccctaaaaat gtaaaggaag gttaaggtga aggccgcaaa aatgagggca
     6661 gtccatcttc ctagaccaat ataggttttc gcatcatcaa atcgcttggc tcccacttca
     6721 taggaaacga caatagccat agccgatgag atactcatag gaaaggcgta cataagactt
     6781 gaaaagttca tagctgactg gtgactagct ataatcaagg acgaaaactt agccataatc
     6841 aagccaacca ctgaaaagac agccacttcc gcgaagacag ttcccccaat aggcagacct
     6901 aaacgaactc cttccttaat tttatccata ttaagtggaa ttcgtttctc aaggtgtaag
     6961 gctttgagct tctcctgttt aaataaaacc agaacagaaa tcccaagcaa gacccagtag
     7021 gccaaggatg ttcctaaacc agcaccagcc cctcccagtt ctggaacacc aaaggcaccg
     7081 taaatcaaga gatagttaaa tccgctattg agagggagta acaaaagcat gaggtacatg
     7141 gacagtttgg tcaagcccag cgaatccagc aaggaacgaa tgacgctaaa gagcaacaag
     7201 gggataatcc cgatagataa aaaccaaaga tagcgaaccg ctactgccgc tactgctgct
     7261 tctaacccaa tatgattcaa gattgttggt gccaagaaaa gtaccatccc cagcaagacc
     7321 acagataggc ccaaggccaa ataaataaat tggtaaaaat cagacgcaac ttcttccttt
     7381 ttgcctcgac caagatggtg accaatgata ggcaccaagg ctgacacaat ccctgttaga
     7441 aatgtaaaga aaggattcca gatactggtt gccatagata caccagccaa gtccatagtg
     7501 ttgtattgac ctgtcattgc agtatcaaca aaagaggcag aataattggc aaattggtag
     7561 atcaggattg ggaagaaaat ttttaaaaat aatactaact tctctcgtaa acactttgtc
     7621 ttatacatac ttctctttct attctgattt atctaaacca aagagtttca gaccatagtt
     7681 tttcaaactt agcggaggtt tattagattt tgaagtagta tgccaacacg cacatgtacg
     7741 acaataatag cttctaacta aacctccgtt atcatattga accgcatggt cagctttttc
     7801 tttagtttca tattgaattt tggaacgatt agctgcggga cagtaaattc cactattaga
     7861 tttcgcttgt ctctccctac gttttcgaaa ataattcata ttctaactcc tatcaagctt
     7921 gatagacgat ttgtccctta cagatagtat atttaacctg cccttttaag gtttcaccga
     7981 tgaatggtga attagctgct ttggaagcaa aatgggagtc cacaaggcgg tcagccttgg
     8041 catcaaaaat agtgatatct gctggaccat tctcagccaa gtaacctgct tcaaagttgt
     8101 aaagcttggc tgggttgtat gtcatttttt caagtaattc catcaagctc aactcaccag
     8161 cttctactaa ataggtcaag ccgagagaca gggatgtttc taagccagtc ataccagatg
     8221 gcgctttggt aatatcctca acattttttt catctacatg atgaggcgcg tggtcagtcg
     8281 caataactgt gataacacct gatttgagac cttcgataac ggcacgacgg tctgattcca
     8341 aacgaagcgg tggattcatc ttagcattgc taccttgtgt taaaagaagt gcttctgtct
     8401 tagagaaatg ctgtggcgct acttctgctg tgacttctgc acctaacccc tgagcaaact
     8461 ccactacttt aacactttct tccttagaca aatgctggat gtgaacatgg gctttagttg
     8521 cataggcaat catgacatca cgcgccatca tagcgtactc agccacccca gtagcaccgc
     8581 agatatgaaa atgttctcta gcaatatttt cattaaagcc aagaacaccg ttcaaacctg
     8641 gatcttcctc atgaaggctg ataaaggtat tgagtttttt ggcttcctcc atggcttcct
     8701 tgacaatctt actgctctca agcggaatac cgtcatcaga gaaaccaacc gcaccagctt
     8761 ctaaaagtgc cttaaagtca gtcaagtttt taccattaaa gtttttagta atggtcgcaa
     8821 ctgtcttgac attaatcttc tctttggcag ctgactggag aactgcttgc aaagtctcca
     8881 cgtctgaaat ggttggactg gtattagcca tcatgacgac agtagtaaaa ccacctgcag
     8941 cggctgccag ggcaccagta tgaatgtctt ctttatgtgt ttgaccaggt tcacggaaat
     9001 gcacatgaat atcgaccaaa ccaggagcaa ccacatgacc agtagcatca atcgtttctg
     9061 ctccttcttc cgtgatctca ggcgcaattt tgataatttt cccatcttga actaagacat
     9121 cacaaacttg atccaaacca gacttgggat ccattacacg accatttttg attagtagca
     9181 tctgctttct cctttattca tagaaatcaa cttgggtatc caacaattta tccccatcat
     9241 aaacaaactt ggctgaaaag aagggtttat cctctaaaag ccactcaaca aaggtgtggt
     9301 caccttccca ggtcggcttg ctcaaaacct catcataggg aacccattct agcatcccct
     9361 cattgcagtc aatcaagtcg ccctcaaact ccgtcacctt aaaaacatag gtgtaccagt
     9421 ctaaatctgg tgtaaattca ggaaaagtga tgacaccttt tagaactggc ttggctttga
     9481 gccctgtttc ttcaaggatt tcacgtaccg cgcattcctg gggcgtctct cctctctcta
     9541 gcttaccacc cacaccaatc catttccctt catggacatc attgggtttc ttattacgat
     9601 ggagcatgag cagttctttc ccattatcaa tgtagcaaat cgtcgctaac tgaggcatat
     9661 tttctcctta tctaagccaa tcgattggct cttgtcctgt ctcttttaag aatgtattgg
     9721 ccttggaaaa aggcttggaa ccccaaaatc ctctataaac cgacaaagga cttggatggg
     9781 ctgattcaat aatcaagtga tgaggattgg taactaaggc cttcttctta cgtgcataag
     9841 ctccccagag tacaaaaacg actggtctat ctagatgatt gaccacctga atcacagcat
     9901 cagtaaaagg ctcccagatt tgaccagcat gaccattggc ctgtccagca ggaacagtca
     9961 aacaagcatt aagaagcaag actccttgct cagcccaagc tgtcaaatca tgagatttct
    10021 taactccgat atcatctgac aattctttca agatattttg caaggatggt ggagctggga
    10081 tagagtcagg tacagaaaaa ctcaagccct gcgcttgacc tggtccgtga taggggtctt
    10141 gccctagaat taccacctta acttcttcaa gcagtgttgt caagagagcc tgaaaaacct
    10201 tttccttggg tggataaata atcccctgag aatagacctg ctccataaac tgattgattt
    10261 tcccgaaata accctcaggt aattgcgcct taatcaaagc atgccaagac gagtgttcca
    10321 tagccgactc cttcattttt actgcctcta ttatagcaaa aagtggctat ggaaaccact
    10381 ttttacagtt tatctaaaga tttaataaat cgactatata cgatttgaat acgtgaatac
    10441 agtttataaa gactggctat tttttataat tactttttaa atcattaagc attttactac
    10501 ctctttcgaa gattatcttt tctgaaatat ttttaaacat attaaaatcc atttcagaaa
    10561 aaggagtttc tttagaaact tgccatatag tctttaaata atttttttct aaaaagtcat
    10621 caaaattaga aaacaatcga aaatacaatg cattctcttg gtgtaaaatc gctcttttta
    10681 aaggataata ctctttaata ttattaactt tttgttcgta ggcatatttt gctacatgat
    10741 ctaggtatat atcaaaaaag tcatgaggaa aatctcccat acagccatta cgattcatat
    10801 tgaggctata ttttcgatta gtaagataat tcggaaatat atttcctatt actctaagat
    10861 tatctacttg tgaatccctt ctcccaatat aatccccttc tttgactaat gatggagatt
    10921 tccaagtaaa aattaaatcg ccagagaaat ttttcttatc aaaaaactta aaaagagatt
    10981 gataaatact atttgctaat tgacaagtgt cagatgtaaa ttcataatta acagcttcat
    11041 taaaatcaac ttcagacatt tcaatgtact cttcaatagt aatattagct ttttttgtag
    11101 tcattagcta atctccttta aaatgtgatc ttttcaagaa tatttttatc taaacaatcc
    11161 agcaagtctt ggtaagaata gacttcgtaa gtcggctggg cttgtgtgtg attttcgagg
    11221 tgatgaggat tataccagat agtgtcaatc cccgcattat tgccaccttg aatgtcggcg
    11281 gttagagaat ctccaatcat cagcgtcttt tctttactaa atccagcaat ttgctggcca
    11341 atcttttcat aaaagagagc atccggcttt tgagtttgca actgttctga gataaagact
    11401 tgattgaaat aaggtactag accagattga gccaaacgtc ctgtctgaat ggcagtaatg
    11461 ccatttgtcg cagcatacaa gtcataatca cgctcaatga ggctgtccaa gagatcatga
    11521 gcgcccgata gtgtttgtcc ctgctgagcg agataaaatt ggtaacgctg ggcaagaaaa
    11581 ctaccgtctt tttcctgtcc aaaatgagaa aataaacgag aaaagcgcgt gttaaccaac
    11641 tcttgtttac tgattttctt cagctccaag tctttccaga gagccttgtt cataggaacg
    11701 taataatctt tataagcctg aatatccgca actccttctt cttttagaag ttgggtcaaa
    11761 gccacatcct cagcagcatc aaaatcaaga agagtgtggt cgaggtcgaa gagtagaaat
    11821 ttgtagaaca atttgaggtt ttcctttctg aaaattcatt aagaacatta tatcataaag
    11881 cacctcatac aattaactaa tttaatcact taaaaaaatt cgaacacttt ctatacaact
    11941 gacagctcaa atctttcaga atagaacaat actaactatc gaacaccccg tcttcataaa
    12001 tacatatgta attctagacc tagaattcct ataaactaaa tgctttcata ctcttccaag
    12061 taattgattg ccttaaattt taatttttga aggattctaa agctagaata gccccatcac
    12121 aatcagtttt gattgattca caatttagaa acactatagt ttcactcctg ttaaaataaa
    12181 aaggaactgc ataaagcaat ccctttctga ttttgaaatc atttacttaa cattttatag
    12241 cagaacctag gtcaaaaaag gcaagtaaag tatctgctgg attttcggaa acaaccctat
    12301 ctacttgatc aaaactcgtt ccaattcctc cgccctcggt tcctcctaca taagtaatcg
    12361 gaacatcttt agctacttta ctaattagtt caacaacacc ttctgcaatg tgtttggaat
    12421 gtgaaacgat aacaagacca atactttcca tcaaaccacc ccagtttcta aaatagcagt
    12481 aaagagtaat cctgatgaga atgatccagg atcaatgtgt ccaagaaacc acatgctcct
    12541 aagacaagag ctaacagact ggccatcaat aatagtattg ttcttttttt catcattact
    12601 ccttaactag tgtttaactg attaattagc cagtaaatag tttatcttta tttacactat
    12661 ctgttaagat atagtaaaat gaaataagaa caggacagtc aaatcgattt ctaacaatgt
    12721 tttagaagta gaggtatact attctagttt caatctacta tattttgcac attttcataa
    12781 aaaaaaatga gaactagaac tcacattctg ctctcatttt tcgttttccc gttctcctat
    12841 cctgttttta ggagttagaa aatgctgcta cctttactta ctctccttta ataaagccaa
    12901 tagtttttca gcttctgcca taatagtatt gttgtcctgg gtgccaaata gtaaattatt
    12961 ttttaatcct gtgagagtct ctttggcatt ggacttgata attggatcct ggatttttcc
    13021 aagtaaatct tcagcctctc tcagtttttc ttcaaccttt tcagtctcga cctgaggttc
    13081 ttctgattcc tctggtgatt cttcttctgg ttcctctgtt ggttttggag actctggttt
    13141 ctcgctttgt ggtttctctt ctcgaggggt ttcttcctca ggtttttctg tctgaggttt
    13201 ctcctcgctt ggtttttccg tttgattggt atcagcttga ccatttttgt ttctttgaac
    13261 atggtcgcta gcgttaccaa aaccattatc tgaatgcgga cgttcgtttg gatgttcgac
    13321 atagtacttg acagtcgcca aaagatcctc aagagtatac cccttaggtg cctcataaag
    13381 gccttcgtca aaccactcaa atttgatgtt atggtaatgg tcataatgag gtatgattaa
    13441 actaccgttt ttgacttcta cagtatattg aagattgtaa ggcatacgat caag
//
LOCUS       DAVDHC010000048        12933 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVDHC010000048 DAVDHC010000000
VERSION     DAVDHC010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.048"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(91..1596)
                     /gene="pyk"
                     /locus_tag="VUR43_002020"
     CDS             complement(91..1596)
                     /gene="pyk"
                     /locus_tag="VUR43_002020"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET5413648.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDETREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(1655..2662)
                     /gene="pfkA"
                     /locus_tag="VUR43_002021"
     CDS             complement(1655..2662)
                     /gene="pfkA"
                     /locus_tag="VUR43_002021"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET5413649.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            complement(2745..5846)
                     /locus_tag="VUR43_002022"
     CDS             complement(2745..5846)
                     /locus_tag="VUR43_002022"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET5413650.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVLEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            6194..8467
                     /locus_tag="VUR43_002023"
     CDS             6194..8467
                     /locus_tag="VUR43_002023"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET5413651.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELKVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQAFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRSDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            8484..8954
                     /locus_tag="VUR43_002024"
     CDS             8484..8954
                     /locus_tag="VUR43_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET5413652.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(9071..9226)
                     /locus_tag="VUR43_002025"
     CDS             complement(9071..9226)
                     /locus_tag="VUR43_002025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413653.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKATLTRIEEI
                     FEEYKSS"
     gene            complement(9497..12847)
                     /locus_tag="VUR43_002026"
     CDS             complement(9497..12847)
                     /locus_tag="VUR43_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET5413654.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDVDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
BASE COUNT         3879 a         2847 c         2206 g         4001 t
ORIGIN      
        1 aatccattat gaaaggtttg ccccctggac aaaaaaaaga gcccatcata caggctagaa
       61 agctggatat gataggtttt tatatttttc ttaacgtact gtgcggatac gcattgtgtt
      121 tgtgcgaaca gcttctccta ctggcacacc agcaacgata acgatatcat cgcctgactc
      181 aacgagacct gcttctaccg ctttacgttc agcgatttcg aacatatcgt cagttgaaga
      241 tggagcatct gtcaacattg ggataacacc ccagttcaac atcaagccac gttctgtcaa
      301 ttcgtcaaat gtcaatgcta agatgtcagc atttggacgg tatttagaaa tcaaacgtgc
      361 agtatgacct gtcttagtaa gagttacaac caatttgata tccattgagc tagtagcatc
      421 tttaacagca gaagccatta cttctgtctt agagttacgc tcaaatgaat ctgaatcaag
      481 acgtccgtat tcattaagaa gagcttgagc gttcttgtcg attgtagcca ttgtagttac
      541 tgactcgagt gggtatttac cgtttgcaga ctcgcctgac agcattgtag cgtcagttcc
      601 gtcgataaca gcgttgaata cgtctgatac ttctgaacga gttgcacgtg gtttttcagt
      661 cattgtttca agcatgtttg ttgcagtgat aacaacttta cctgcagcat tgactttctt
      721 gataatcatt ttttgataaa ctggaaccat ttcgaacggt acttcgatac ccatatcacc
      781 acgagcaatc ataataccat cagctgcttc gatgatttcg tctaagttat cgataccttg
      841 ttggttttcg attttagcga acaattgaac atgtccgttt ccagtttctt cacagattgc
      901 acgaacttcg ttcacatctt ttgcagtacg tacgaatgaa attgcgatga agttgatacc
      961 ttgttcaaga ccgaaacgga tatcgtcgtt atcgcgttca gcaagagctg ggaaaggaat
     1021 tttagtgtta gggatgttca cacctttttg tttagcgatg ataccatcgt tttcaacttc
     1081 aacttcaaat tcacgagttt catcatcttt agcaaccaca cgaagaccaa gtttaccatc
     1141 gtcaaccaaa acttgacgac caacttcaac atcatcatag atatcaagag caccagcaac
     1201 gttcaacgca atcacttcac gagttgattt gattccttgt ttagttgcaa cacgaatttt
     1261 ttcaccagtt ttgtatgaat attctttagc ttcaccttcg aacaattctg tacggatttc
     1321 aggtcctttt gtatcaagaa ggaaaccaac ttttttacct gcaatttttt ccgcaagttt
     1381 aacagttgcc atacgctcac cttgttcttg gtggtcgccg tgtgagaagt tgaatcggaa
     1441 tgtgttagca ccagcttcaa tcaatttagc aatgttttta gctgaagctt caacatcaag
     1501 tttttcaccc cagtatccgt cctcaccgaa ttttttacca ccacggattt ctaccgcagg
     1561 acccaaagtt gcaacgattt ttacacgttt gttcatgatt tttgtgactc ctttatatat
     1621 atgacctttt tggtcttatt aactaaattg taaattatga caagctctta ttcaagctag
     1681 atagctcaat atcggctttg tgtgggttgt taaccacaat cttaccttct gcagtaaggc
     1741 taaacaatgc cccttcttct gcagtaccaa gaattggatt ttcaaccatt ttttcgttac
     1801 gaataccaac cgcaacacca ccgatacctt ctttaagaag tttaacagca tgtgcaccca
     1861 tacgtgacgc caaaacacgg tcacgcgcag ttggagaacc accacgttga atatgtccaa
     1921 gttctgttac acgaaggtcg cttgtatctc cagcttcttt aagtttttga ccaaattcag
     1981 ccgctgacat cacaccttca gctaagacga tgatattgtg ttttttacca cattcataac
     2041 cagctttgat gcttgctacg atatcttcca tcttgaagtc tgcttcaggg atgatgattt
     2101 catcagcacc agttgcaata ccagcccaaa gagcgatatc accagcgtta cgtcccataa
     2161 cttcgattac aaaagtacga cggtgacttg atgatgtatc acgaatctta tcaatagcgt
     2221 ccatggcagt agtaaccgct gtgtcaaaac cgattgtaaa gtcagtacca acgatatcgt
     2281 tatcgattgt acctggaaga ccaatagctg ggaagccatg ttcagtcaaa cgcatagcgc
     2341 cgtggtaaga tccgtcacca ccgataacaa ctacaccttc aattccgtgt tttttcaatt
     2401 gctcaatccc tttaagttgc ccttcaagtt gagcgaactc tggataacga gctgagtgaa
     2461 gaaaagtacc accacgagaa atgatgtctc ctactgaagc tgcatctagg ggatgaattt
     2521 caccagcaac cataccagca tatccgtcat agataccaaa cacttccatt ccttctgaaa
     2581 ttgcttgacg aacaactgca cggatagcag cgttcatacc aggtgcgtct ccgccactag
     2641 tcaaaacagc aatacgtttc atattggttt atgctccttt ttcttttaac attcttcttg
     2701 attatatcac atttgatttt aaaattcttc tattttccgt atttttagcg ataaatcgtt
     2761 ttcataacga tttcattcaa tttctcctct aattcattgg atttagctac aaaatgatgg
     2821 ggagaaacga tggttttctg ttcctcttca taccggatga tgactgggat tgggccttta
     2881 aattgttcta aaatacgtga aatttcttga tccgattcat gatttttcac ctgtatccaa
     2941 aagcgttcag caactgcttc tcttatttct tgtgcaatca tttgcagacg gccatcacgt
     3001 gattgtattt ttccttttac atagtagaag gctccctctt ttatttcctg tccgacctga
     3061 cgatataagt ctgaaaagag agtgacatcc aattttttct tactatcatc tgcctgtaag
     3121 aaggccatat tttcaccctt tttggtacga atcactttta ttttctgaac ttcaaccaaa
     3181 ataatagcat agctattttc tgacaaattt ccgattgggg taatcgggta aatagcctta
     3241 cttgcaatag cttgtagtgg atgtttgctg acacctatcc ctaaaagctc ttgttccata
     3301 taaaattttt cttgttccgt ccaatcttcc gattcctgcc aactataaat agcatctcca
     3361 aacaaacttc ccaactcttt cacaaattca aatagattag ctaagttatt aaatactttt
     3421 tgacgatttt tttcaaatga atcgaaaaga ccaactttta ccaaaggttc tagcagagga
     3481 agtttcagat aattctcagg taatttagct ataaaatctt caatgttaga ataaggtcta
     3541 tgttcaataa tccagagagc taaatcatta ctgactcctt taatggattt caaacctaga
     3601 tagatggcct tgttggcaat tttatcgtga tagggaatcg tgttgatgga caatggggct
     3661 acttcaaaac ctgcttctaa ggcatctgtt acataatcac tgttagcaga attcaacata
     3721 atctgataaa atatggctgg ataatgtgtt ttaaaataag ccaactggaa ggccaaggct
     3781 gagtaggcgt aggcgtgtga cctgttaaaa ccatagcctg caaacttctc cagaacatca
     3841 aaaacctgct ctgctttttc cgcagtatgg cctgcttcta tggagccttg aataaaggaa
     3901 gccctcatct catgcatagc agaagcatcc tttttaccca tagctcgacg caaaatatcg
     3961 gccttcccaa gactaaatcc agcaaatcgc tgggcaacct gcataacctg ctcctgatag
     4021 agcattatgc cgtaggttgg agccaaaata tcctccagta ctggatccag aacagtcact
     4081 tcttcctgcc catgctttct tgccacaaaa ttattgatat agtcactagc acccggtcga
     4141 tttagagaag tagtcgcgac gacatcttca aaacagactg gttgcacacg cttaagcaga
     4201 cgaatggcac ctggttgctc aaattgaaag ataccttttg tattaccaga ggcaaataaa
     4261 gctaacgttt ctttgtcttc taaatcgatt tcttcaattt tcagatgaat accttctgtt
     4321 tcagcaagca actcttgcat cttctggaca aaggtcaaat ttcgtagtcc cagaaagtcc
     4381 atcttcaaaa gtccgctagc ctcaactcca tgagcatcat actgagtcag tggaatttca
     4441 tcaccatact ttagaggaat gtagttggtt aaatcttggt cactaattac aacaccagcc
     4501 gcatggacag aggtttgcct tggatagccc tctatcttgc aagcaatctc aaaagctttt
     4561 tggtattcta acttactatt gatttgctga cgaaactgga gattgccctc ataggccgac
     4621 ttaagattgt cacgaaaact gattttctta gtaattgcag ataattcata ctctggcaca
     4681 ccaaagcgtt tcaagacatc tcgaagagct tgcttggctc caaaggttga aaaagtaacg
     4741 atttgtgccg catgtttact accatattta ttaccaacat atctgataaa atctggacga
     4801 taaatatctg ggatatcaat atcaatatca ggcatggtat agcgttcacg attaagaaag
     4861 cgttcaaaaa tcagattttt ctctactggg tcaatccccg tgatgtctaa ggcataagaa
     4921 accaaactgc ctactgcaga accccttccc attcccatat aatagccatt cgatcgtcca
     4981 aaacgcaaca aatcccaaac aaccaagaaa taatcatcaa agcccatatc atgaataaca
     5041 gacaattctt ggtctagtct atcttgatat tctttactag tcaacccctt ctgaacaagc
     5101 cccagttcag cacgctctct caactcctct actgctggtc tagctggatt aaaacgaggc
     5161 agtttcagac tagtatccaa gtcgtaagaa atgcctgaaa taagcttttc taaattgtcc
     5221 aaagcttgcg gaaaacgctc ttggaatagt ttctctaaag aacttgctga tataaagaca
     5281 tcttgtctcg aacgcaaggg aacttctctg agcggtagat tttctttaat cgctgttaaa
     5341 acttgaagaa cttctctatc cctgctttca aaagcgttga cccgataaag aggtaagata
     5401 ggatgatgaa attcgcttgc tagtgtttct ggataaaccc ctatatagta atcacagcct
     5461 agttctaacg actcaactct atcaaaataa ggcacaatga ccgcgatatc ctccaggtac
     5521 tgggacagga ctgaccaagt tttctccccc tgcatcttgg ctgtcgaaag cttcatcaac
     5581 tgctgatagc ccacactaga tagagctaaa aagcgcaaat tcacttcctg atcatctaca
     5641 aacactgtca tttcaagccc tagcaaagga tgaatgccgt atttttttgt aatctctaga
     5701 aagtcgaaag cgccataaag attgtcaata tccatcatag ccaaatgagt gtagccgtat
     5761 tctttagctg ctctcacata cttttcgatc gaaatgacgc tttccataaa actatagact
     5821 gtttttgtat ctagttgtgc gatcaattta cacttctcct ctatccttct cactatatta
     5881 taccattttc acctataaat ggcttctctt gagaaaaatt tcatcagctt actaatttat
     5941 tttctattca tttgtatttt tgtcatcatt tttatattta tactatattg tatataaaaa
     6001 tagaaagcat ataatataaa tctcctagaa cttttatacc ctatctattt tattcttatt
     6061 gttactctgt tctctatatt gaatttagta ctttattcat ttttattgga ttatttcctt
     6121 ttgaagttaa caattccctt tctgcttttt ttttgatata ataaccttaa ctgtcattct
     6181 atatggaggt tctatgcgtt ttaatcaata tagttatatc aattttccaa aagaaaatgt
     6241 cttatctgaa ctaaaaaaat gtggctttga tttacaaaat acagccaatc acaaagactc
     6301 acttgaaacc tttttacgtc gtttcttttt cacttatcaa gacaccaact acccactttc
     6361 tatcctagca gctgataaaa aaacagacct gctgacattt tttcaatcag aagatgaact
     6421 gacagcagat attttttata ctgttgcttt tcaactttta ggcttttctt atttggttga
     6481 cttcgaagat agtgacgttt ttcgtaaaga aactggattt cccattatat atggtgactt
     6541 gattgaaaat ctctatcagt tactcaatac tcgcaccaaa aaaggaaata ctcttatcga
     6601 ccaacttgtt agtgatggtc ttattccgga ggataatgac taccactact ttaacggcaa
     6661 gagtttggct actttttcta accaggatgt cattcgtgaa gtcgtttacg ttgagtctcg
     6721 tgtcgatact gaccaaaaag ggctatcaga cctagtaaag gttagcatta ttcgccctcg
     6781 ttttgatgga aaaatccctg ccatcatgac agccagccct tatcatcagg gaaccaatga
     6841 caaggctagt gacaaggctc tctacaagat ggagggcgag cttaaggtta agcttcctca
     6901 caagattgag ctagagaaac ctcaactaaa tctcgtccaa ccccaaggtc aagctgagct
     6961 tatagcagag gctgaggaaa agctaactca catcaactct agctatacac taaacgacta
     7021 cttccttccg agaggctttg ccaatctcta tgtctcaggt gttggtacca aagactcgac
     7081 aggtttcatg actaatggag actaccagca aatcgaggct tataaaaatg tcatcgattg
     7141 gcttaacggc cgttgccgtg cctttactga tcacacgcgc cagcgtcaag tcaaggctga
     7201 ttggtcaaac ggaaaagttg ctacaacggg actttcctat ctaggtacca tgtccaatgg
     7261 tcttgcgact acaggagtcg atggtttaga agttatcatt gccgaggcag gaatttcatc
     7321 atggtacaac tactaccgtg aaaacggtct ggtgactagc ccaggtggtt atccaggtga
     7381 ggactttgac tcccttgctg agttaaccta ttctcgtaat ctcttagctg gcgactatat
     7441 ccgtggcaat gaagctcacc aagctgactt agaaaaagtg aaagctcagc tagaccgaaa
     7501 aactggggac tacaatcagt tttggcatga ccgcaattat ctgctcaatg cccataaagt
     7561 aaaggcagag gttgtcttta ctcatggttc tcaggattgg aatgtcaaac cacttcatgt
     7621 ttaccagatg ttccatgctc ttcctactca tatacacaag catctctttt tccataatgg
     7681 tgcccatgtt tacatgaaca attggcaatc aattgacttc cgtgagtcca taaatgcctt
     7741 attaaccaag aaattactag gacaggaaac agactttcaa cttcctactg ttatctggca
     7801 ggacaataca gctccacaga cttggttatc acttgataac ttcggtgggc aagaaaactg
     7861 taaaaccttc tcacttggtc aagaagagca agctattcaa aaccagtacc cagataagga
     7921 ttttgagcgc tatggtaaga cataccaagc cttcaataca gagctctatc aagggaaagc
     7981 caatcagatt actattaacc ttcctgtgac taaagatctc cacctaaacg gtcgcgctca
     8041 gctcaatctt cgtatcaaat ccagtacaaa caaggggctc ttatctgccc aactgctaga
     8101 atttgggcaa aagaaatacc tacaacctta tccagctatt ttaagtgcta gaaccattga
     8161 caacggtcgc tatcacatgt tggaaaatct ctgtgaattg ccatttagac cagaggcaca
     8221 acgagtcgtg acaaaaggtt accttaattt acaaaataga agtgatttac tgttagtaga
     8281 ggatattact gcagatgaat ggatggacgt tcaatttgaa ctgcagccaa ctatttacaa
     8341 gctaaaagaa ggagacactc tccgtttagt cctctatact actgactttg aaatcaccat
     8401 ccgtgacaat acagactacc acttgactgt cgacctcgct cagtccatgc ttaccttacc
     8461 ttgctaaaag gagttacatt attatgaata aatcagaaca ccgccaccaa cttatacgcg
     8521 ctcttatcac aaaaaacaag attcatacac aggctgagtt gcaagccctt cttgctgaga
     8581 acgacattca agtaacccag gcaaccctct cacgcgacat caaaaatatg aacctatcaa
     8641 aagtccgcga agaagatagc gcttattatg ttcttaacaa tggttccatc tcaaaatggg
     8701 aaaaacgtct cgaactctac atggaagacg cccttgtctg gatgcgccca gttcaacacc
     8761 aagtcctact aaaaaccctt cctggactgg ctcaatcctt tggttctatc attgatactt
     8821 tgagcttccc tgacgctatc gctacccttt gtggtaatga tgtctgtctt atcatctgtg
     8881 aagatgcaga tactgctcaa aagtgctttg aagaactgaa aaaattcgcc ccaccatttt
     8941 tctttgaaga ataataaatg actacaacta acaattatgc ttaaaaaaaa actggtagaa
     9001 agtctttaac atcagaaaac gcatagtatc aagtgttgaa aacccttgat actatgcgtt
     9061 ttgctttatc ctaggaagat ttatactctt cgaaaatctc ttcaatccgc gtcaacgtcg
     9121 ccttgccgta ggtatggtta ctgacttcgt cagtttcatc tacaacctca aaacagtgtt
     9181 ttgagcagcc tgcagctagt ttcctagttt gctctttgat tttcattgag tattatttca
     9241 ttttctcctg caattgaatt cttgctcagc tttttgtttt ctatttcttt aaaatcaaag
     9301 tagctctttt gttaataact cgatcaacaa acatcgtggt acaagtatct actttgaaat
     9361 ttatcaacca cttaacaact gatactgtat tctaggaaaa cgatgacatt cttcctaata
     9421 aaacttctca tatatagcat aaatttctac tctttttaat tttaaatgag tctcagcatg
     9481 gcaatcactt tagaatttaa gccgcttctc cagctcgatt attgataagt tcaatgattt
     9541 gaacaatatt acgaagtact ggtagttggt gttggaagag tagttgaaca gatccataag
     9601 atttaaacgg ctcttgcgtt aacactttcg tctctaaaaa accattttct acaatgtagt
     9661 ctacaatcaa ttttacaaat gaaatctgcc tggcattaag attctcatcc gacaaaaatt
     9721 tagaaaaaat acgattggca gactctctat ctaaaccaat aatctcacga accaatctcg
     9781 gaattgcctt attttcataa tgactttggt agtctgcttt actacctaat ttttcccaaa
     9841 gcaatttttc aagtgcaagc atatcatcag atgtcaactt tttattatgg tatagcttag
     9901 aaatggactc ctcatccaga tgagttttca aataatgctc aactttttca ttgtaagacc
     9961 gaagatcgtt gacctgcaaa aatgctgtgg tctcgtgaac agtggagagt atacgatctt
    10021 caaagttaac atagtagggt ttacggtctg ttttatccaa aaactgtaat aaatctcgaa
    10081 tagcaagacg aattttttcc aaatcagaca agttaacttc tttccaaaat tcaggctcct
    10141 gtactttcct gataatttca gcctgctcaa aaacctgcgg gatattgcca atagcagaaa
    10201 gagctctagc cgtcttcatc acttgggaaa tatgaacagt ggaagattta gctgtcagtt
    10261 gccccaactg aatatgaagc aaccacaaat caaatctcct cgccatctca tcttctttat
    10321 cttcatcaaa taaaagcgga gagagatttt tttgaatggt ttcacttgta acagcagtta
    10381 gattctgcca actttccaat ttcctatagc tataaactgt atctaaaacc atacgaaccc
    10441 tgaagtccaa ctcatttaag ctctctatac gaccttgaag ttccgagaca agctgctgac
    10501 ggtatgctct cgcaaactga tcttcttggt attggagtcc ctgaagttct cgaatcaagt
    10561 ccactttgat attaaataaa cgctgagtca gcgaaacaat gtgacgaccc tctccatctc
    10621 ttggatctgc acgaaaataa tcaaaattgt ccccataatc aaataccaag aagttttcct
    10681 tatcctgctc aggtccaaat aaatctttac atagacgggt tcctcgacca atcatctgcc
    10741 aaaacttagt tttagagcgt actttcttga agaagactaa attaacaacc tctggtacat
    10801 caatacctgt atctaacata tcgacagaaa tcgcaatttg aggatacttc tccttaattt
    10861 taaaatcatc aatcaaggtc tgataatgct taatactata atcaatcacc tgagcatagt
    10921 cgctcccttt ttcaggatag cggttgttaa aaatacctct gatatattcc gcatggtcat
    10981 gatttttagc aaaaataata gttttaccaa tttcatcacc cgaggctgtc tgaattcctc
    11041 ttgtcatgag ttcatttaaa acaatttcta ctgtactttt attgaaaata aaggaattaa
    11101 acacactccc atcaatatct ttttcacagc tatcgtcttc aaatttgcta tcaaaatgtt
    11161 ccttttcttc ttcggacaaa tcatcataat gtagaccatc cgtaggtagt ttcagtttgg
    11221 tttcgataga atgataggct actaaatatc cgtctttaac agcctcttcc aaatcatatg
    11281 catatgttgg aaccccattc tccaaattaa agaatccata ggtgttttta tctaaatctt
    11341 gacgcggagt agctgttaag cctacaattc ttgcatcaaa ataatcaaaa atggacttgt
    11401 atttctgata aatagaacgg tgagattcgt caattatgat aaggtcaaaa tgcccaacag
    11461 tgaaagggcg ttgatttact tcttcttgac cactaatcgc tccaatcatg gtcggataag
    11521 ttgaaaagac catgcgactt gattgagctc cttctttatc ttctaagaag ttacaaacgg
    11581 aaagatctgg gagtaatttt ctaaacgaat cataggcttg cttaaccaag gaagttctat
    11641 cggctaagaa gagaacgttt tttacccagt tatgacgtga taagatatca actagagaaa
    11701 ctgctgtacg agttttccca gccccagttg ccataaccaa aagtgcctgt ctacgatgat
    11761 tagagaaagc ttcacaaacg cttgcaatgg cgtgtttttg gtagtgacgc ccggaaatat
    11821 cgtccctaat tttactagaa atatcctcaa gtggtttttg aagatgacgt ctatccatca
    11881 ctaattgcaa ttcttcttga gagtaaaagc ctgcaatctg gcggcggttc ggaccatcaa
    11941 gtatatagtg cttcaagcca tttgtaataa agcaaattgg ctgatagccg atatgtttct
    12001 caagagcttc agcatattct ttgacctgta cttcccctac ttctggattg acagaggctt
    12061 ttttagcctc tacaatcgct aaaattttcc catttttacc ataaagtaca tagtcacagt
    12121 aaccaattcc tgaaccgtgc ttgagaccat caacggctat ctcaacacga cagttttctt
    12181 caaatatcca tcctgctaaa cggagatcga catcaataaa gagctttctt gtctctgcct
    12241 cagataattg atcaatatgg aaaggcacat cttgccgttg cgctgcagtc tcacgttttt
    12301 cagtataagt ctcttgaact tctacggact gagcagccat ctgttcatga aaatcaggca
    12361 gttctggtaa actgtcttgt aactttatca tagattgtgg agtttctcgg tatttgatgt
    12421 ttgctgaaag tggtaagcac ttctcatcaa aataacgctc cacaaactca ttgctgtaac
    12481 aataatcgat aaaattaaca aactgataca aatgatgcaa agctaaaatc gcttctcgtt
    12541 ccttaatttc accaccatga gcagcatggt ttccccaccg aatcaacaga actatctgct
    12601 tgtggagttc agaatctacg atatccctaa aatcatcatc ccatactaaa gaagatagag
    12661 tagcacgata gggagcttct aaatatgaat cgtgactata tatccaatgg acagcctgct
    12721 ctaaagcacg acgcgccata aaggcagtag ccacagttga tgtagcaatc atattctcag
    12781 cttcaatgca aggttttgaa aaagattcat attcgtcatt ttttaaaaga aagctaaaat
    12841 ttcccatttt tttctcactt taaacaaata gtttagctat attatactaa atttcaagct
    12901 atttctccac acttttatag ctatctcaca agc
//
LOCUS       DAVDHC010000049        12881 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVDHC010000049 DAVDHC010000000
VERSION     DAVDHC010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.049"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(96..1262)
                     /locus_tag="VUR43_002027"
     CDS             complement(96..1262)
                     /locus_tag="VUR43_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET5413655.1"
                     /translation="MKITEVIKKDGSKVYRANVYLGVDQVTGKKVKTKVTGRTQKEVK
                     QKANQEKIAFQKAGSTRQKAVTIKNYQELATLWLESYKNTVKPNTQGNVKKLIDNHIL
                     PIFGAYKLDKLTTPLIQSIINELADKTNRGEKAAFLHYDKIHALNKRILQYGVTMQAI
                     PSNPARDVVLPRNTQKAKRKKVKHFENQELKKFLGYLDNLDTHRYRYYYETTLYKFLL
                     ATGCRINEALALSWSDIDLDNAVVHITKTLNRDIEINSPKSKASYRDIDIDQATVSML
                     KQYKLRQTKEAWKIGQRERVVFSDFIHEYPSSSRLKRRLQTHFKRADVPNIGFHGFRH
                     THASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            complement(1347..2861)
                     /locus_tag="VUR43_002028"
     CDS             complement(1347..2861)
                     /locus_tag="VUR43_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HET5413656.1"
                     /translation="MRKYDIPKLLLSGENQGVEFKEAKNSFPKDGMKTICSFANTNNG
                     LLILGVSENTKNKDFYISGVNDPDKVLDELYSLLNNPNKINRNVINEESVEVVNIKGK
                     EIVIIPVNKVDYKDKPIYLNDNIASTYFRQGTGDFRCSQEQINSMLRDSAKESFDSTL
                     IQDFSILDLDTETIKLYREKFDNINAEHPFSKLDNEQFLIKINALRRDRKDDKIKPTV
                     AGLLIFGTHNSIKEFIPHYNVEYVLKEFSENNRFKDRVIYDGTWGEDNLFNFFYLVIE
                     KLYLTLNDNSNIQENSMNRIGISKLRIAIREAFINSLIHSDYKSEKGIMIIRYPDRYI
                     FTNGGTLRIDIKDFFSGAHSDPRNYLIQEIFRFLNLCEKAGTGIPKIMEAVKESHLKY
                     PNLRTELDSVEFTLWDTSLIDNLDIDNEYEKKILELIIEHRFVTREALEEKLKIHKNT
                     ILKYLKKLVEKQAIDKFKSGRQYVYFITQNQDPEFQKYNHINAMYSLLEEIKRK"
     gene            complement(3022..3735)
                     /locus_tag="VUR43_002029"
     CDS             complement(3022..3735)
                     /locus_tag="VUR43_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5413657.1"
                     /translation="MAKNSPQDLKNREYFSNNLNRVMKEKGIRQIDLHNALEIPKSTI
                     TGYVKGRSMPTSGNLQKLADYLGVKKSDLDPRFSDKDVYKEFLYMLDKQLDEEKYLVK
                     NVSKDKIFQKVKEREKRDKEIIELAKSKNFPISPEEFLTTITESLNEYNPKDNYEVLN
                     ALALKTSNILFWLDIVFQKTSSEFYIVFEDKEFNQEYYNKLYKKFENLFEEIKSLALQ
                     EAKKDKENLDDFALLWGID"
     gene            3888..4117
                     /locus_tag="VUR43_002030"
                     /pseudo
     CDS             3888..4117
                     /locus_tag="VUR43_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            4133..4759
                     /locus_tag="VUR43_002031"
     CDS             4133..4759
                     /locus_tag="VUR43_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HET5413658.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIETWEAKPKHAHSTMNNLLLKAVTDMNAKQLREERGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            5131..5583
                     /locus_tag="VUR43_002032"
     CDS             5131..5583
                     /locus_tag="VUR43_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413659.1"
                     /translation="MTETTYENLTRHIDRISAEMREIGEKNGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSHKIEAVSKSTTGMFFHAGIFEMDAMRQAFFKRQAMHFFDNEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            5580..5780
                     /locus_tag="VUR43_002033"
     CDS             5580..5780
                     /locus_tag="VUR43_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413660.1"
                     /translation="MTLNLDNMTQAEFDEVMAEIKEKRPNLFQFIADFVDRKVSTEEV
                     DEYLKMKHEKQVEFIKNYQARA"
     gene            5782..5997
                     /locus_tag="VUR43_002034"
     CDS             5782..5997
                     /locus_tag="VUR43_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413661.1"
                     /translation="MNELDLTNTQSVIFMVVLIGLLLYLNHRDRKKSAQFERENQQRI
                     ETPSEDLSPDYGRYIQLAGVRVYGGTE"
     gene            5994..6335
                     /locus_tag="VUR43_002035"
     CDS             5994..6335
                     /locus_tag="VUR43_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET5413662.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LITRHSVPIVGVRHGTFRGYFIPANKEELLDGAKAFYNQVQEEQKRLTVLLNADLESY
                     KETLKEVGGYV"
     gene            6328..6609
                     /locus_tag="VUR43_002036"
     CDS             6328..6609
                     /locus_tag="VUR43_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET5413663.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEARDTVKPRLTGLISAQEVM
                     DELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYKISDIWKFLGVENGKV"
     gene            6744..7610
                     /locus_tag="VUR43_002037"
     CDS             6744..7610
                     /locus_tag="VUR43_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HET5413664.1"
                     /translation="MTIYEAKGFQSNLVYPFDKIEPFQYIERFKPLVVPEGADIEEYK
                     RTQAPYCISGKVTPEKHGSYKRNNSSLIYRDLIFLDYDDIQGTSEGFIKAISSALFGY
                     SYILYPTIKHSLEKPRFRLVVKPDNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPASYQKIVEHGLDYPVPQTTAEPVKQNAASLPYTPRPSGQKSMTMRIIDT
                     LFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTF
                     SSIARAEYRKRG"
     gene            7663..9132
                     /locus_tag="VUR43_002038"
     CDS             7663..9132
                     /locus_tag="VUR43_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HET5413665.1"
                     /translation="MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNENTGDVTEKV
                     AMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDV
                     RIKPREWPQIKLMVRTLAKIRKPLESANLIPVQNGIINLETKELLPFSPKYVITSKIS
                     TAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAIFYG
                     DGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYLKNP
                     SDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVPFNA
                     DFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDNDYL
                     LSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQLTP
                     NRYSLRKKRVSPEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            9495..9662
                     /locus_tag="VUR43_002039"
     CDS             9495..9662
                     /locus_tag="VUR43_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413666.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEIDDFMATVEVLDVKFSGTPSSESF
                     NSVAIVLVLYR"
     gene            9746..10276
                     /locus_tag="VUR43_002040"
     CDS             9746..10276
                     /locus_tag="VUR43_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413667.1"
                     /translation="MTLKTFSSKAKTFTFTYEFKDLDTALVAGHALLGYMTGTYCQPV
                     ISLTYKDKGTLVAEYVEDHKLNKTFKRICDSFKDYHKQPGEAEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELELLDYADRLLSDKPIPMDSMTAFATLEMLGDESISLLQKLD
                     VEGEYKGLAGYTEHLK"
     gene            10347..10856
                     /locus_tag="VUR43_002041"
     CDS             10347..10856
                     /locus_tag="VUR43_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413668.1"
                     /translation="MKQLAIEAITKPMKLRGISKGIAELDGQRLEIDLDSLMIDFGGE
                     SFELDRIAGTKGGNRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKHTLNRSKTDCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDSFPERPKYMKQKRYYKHYQKFINYTRKGDSF
                     WLNGLSSLR"
     gene            12063..12482
                     /locus_tag="VUR43_002042"
     CDS             12063..12482
                     /locus_tag="VUR43_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HET5413669.1"
                     /translation="MTPEQVKEKLEGVKWINKEIKGLYLELETLEGGIIKKPTLSHSR
                     VQTSRENKTENNLISVLKLKEDTLQRIERLTEERMKISELIDKLANPLERSVLRLFYL
                     NDLVVSEVAEEIDRSNTTVYIIRQKAIEHLTGIVNGD"
BASE COUNT         4295 a         2257 c         2576 g         3753 t
ORIGIN      
        1 ttttcaaata aaatcttaca aagacaccgt tgttattgga tttttacttt gtcttgaaat
       61 gttgattttt aaatttgctc ccctttttgc tccccctata gtgcttttag tgcagtttcg
      121 tagaatgata ctgctttttt tgcgttctct tttgagaggt gactatatat atccatggtc
      181 attgataaag tggaatgacc taggcggtac tggagttcct tgtatggtat tccagagtta
      241 agcaagagac tagcgtgagt gtgacggaat ccgtgaaatc caatgttagg aacatcagca
      301 cgcttaaaat gtgtttgcaa tcttctttta agtcttgaac tgctaggata ctcatgaatg
      361 aaatcagaaa ataccacgcg ttcacgttgc cctatcttcc aggcctcttt agtttggcgt
      421 agtttgtact gcttcagcat gctaacagtc gcttgatcta tatctatatc ccgataacta
      481 gccttagact ttgggctatt gatttctata tcccgattta gtgttttggt aatatgcaca
      541 acggcattat ctaagtcaat atcagaccag gaaagagcta aagcttcatt gatacggcaa
      601 ccagtagcca ataggaactt atagagtgtt gtctcatagt agtaacgata tctatgagta
      661 tctaaattat cgagataacc aagaaatttt tttagttctt gattttcaaa gtgctttact
      721 tttttccgct ttgctttctg agtgttacga ggtaaaacaa catcacgcgc aggattggac
      781 ggtatagcct gcatggttac gccatactgt aagatacgtt tgtttaaagc gtgtatcttg
      841 tcataatgta gaaaagccgc tttttcccct ctattagtct tgtcagcaag ttcgttgata
      901 attgactgga taagtggagt agtgagctta tcgagcttgt aagccccaaa aataggcaat
      961 atatgattat cgattagctt tttaacattg ccttgagtgt ttggcttaac cgtattctta
     1021 taactttcca accagagagt tgccaattct tgatagtttt ttatggtaac agccttttgt
     1081 ctggtagatc ctgctttttg aaaagctatt ttttcttgat tggctttctg cttaacttcc
     1141 ttttgtgtcc gacctgttac tttggttttt actttctttc ctgttacctg gtcaactcct
     1201 agatatacat tagcacgata aactttgcta ccgtcttttt ttataacttc agttattttc
     1261 atgatgataa acctttctaa aatacatcag caggcaagcc attatcaaaa aggttttata
     1321 tcatgctagg agctacgaga acccccttat tttcgtttta tttcttccag taaagaatac
     1381 atagcattaa tgtggttata tttttgaaat tcaggatctt ggttttgtgt aataaagtat
     1441 acgtattgtc taccagattt gaatttatcg atagcttgtt tttccactaa tttttttaaa
     1501 tattttaaaa ttgtattttt gtggattttt agtttttctt ccaaagcctc tcttgttacg
     1561 aaacggtgtt cgattattaa ctctaatatc tttttctcat attcgttatc aatatccaga
     1621 ttatctataa gggaagtatc ccataatgta aattcaactg agtctaattc agttcgtaaa
     1681 ttgggatatt ttaaatgact ctctttaact gcttccatta ttttgggtat accagttccc
     1741 gctttttcac ataaatttaa aaatctaaaa atttcttgta ttaagtagtt tcttggatca
     1801 gaatgtgccc cactaaaaaa gtcctttatg tcaattctaa gtgttccgcc atttgtgaat
     1861 atatacctgt cgggatatct aattatcatt atcccttttt cgcttttata gtcgctatga
     1921 ataaggctat taatgaatgc ctcacgaatt gcaattcgta attttgaaat tccaattcta
     1981 ttcatagaat tttcttgaat gttagagttg tcatttaaag ttagatataa tttttcaata
     2041 actaggtaaa agaaattaaa aagattatct tccccccatg taccatcata aatcacacga
     2101 tctttaaagc gattgttttc agaaaactct tttagaacat attctacgtt atagtgtgga
     2161 ataaactctt ttattgaatt atgtgtacca aaaattaata gtccagcaac tgttggcttt
     2221 attttatcgt ccttgcgatc tcttcgtaaa gcatttattt ttattaaaaa ttgttcgtta
     2281 tccaactttg aaaaagggtg ctccgcattt atattatcaa atttttctct atatagcttt
     2341 attgtttctg tatctaagtc taaaatagaa aaatcctgaa taagtgtgct atcaaaactt
     2401 tccttagcgg aatctcttaa catagagttg atttgctctt gtgaacacct aaaatcacca
     2461 gtcccctgac gaaaataggt agatgctatg ttgtcattaa gatatatagg tttatccttg
     2521 tagtctacct tgttaacagg gataatgaca atctcttttc cttttatatt tacgacttca
     2581 acactttctt cattaatcac atttctatta attttattag ggttattaag taaactatat
     2641 aattcgtcca gtactttatc gggatcatta actccagaaa tataaaaatc tttattcttt
     2701 gtattctctg agacacctag aattaacaga ccattatttg tattagcgaa ggaacaaatt
     2761 gttttcatac cgtctttagg gaaagaattt ttagcttctt tgaattcaac accttggttc
     2821 tcccctgata ataacaattt tggtatatcg tattttctca ttttttctcc aatcaatttg
     2881 cacacgcatt cgcacacgcg cgggaaaaat agtttatttt tagttagcta acagtgctat
     2941 taaaggtttt tttgaaagta gattattcgc acacgcattc gcacacgcgc ttcaggattg
     3001 ttgaacattg tggcgcgtgg gttagtctat accccaaagt aacgcaaaat catctagatt
     3061 ttctttatct ttcttagctt cttgaagagc taaagactta atttcttcaa atagattttc
     3121 aaacttttta tataatttgt tgtaatattc ttggttgaat tccttatctt caaaaactat
     3181 gtagaattca ctacttgttt tttgaaatac aatatctagc cagaatagga tattacttgt
     3241 ctttagcgca agggcattta aaacttcata gttgtctttg ggattgtatt catttaatga
     3301 ttcagtgata gtagtgagaa actcttcagg actgattggg aaatttttac tctttgctag
     3361 ttcaattatt tccttgtctc ttttctctct ctcttttact ttctgaaaaa ttttatcttt
     3421 tgaaacattt tttacgaggt atttttcttc gtctaattgt ttatctaaca tatataaaaa
     3481 ttctttgtaa acatctttgt cagaaaagcg agggtcaaga tcagattttt tcactcccaa
     3541 ataatcagca agtttttgaa gattgccaga tgttggcatt gatctacctt ttacataacc
     3601 agttattgta cttttaggaa tttctaaagc attatgcagg tctatctgtc tgataccttt
     3661 ttctttcata acacggttaa gattattaga gaaatattct ctattcttta aatcctgagg
     3721 gctatttttt gccattgtta aaaactccct tactttaatt ctacaacctg attataacac
     3781 aaaaaagaca aagtacgaaa aaaataaaat ttttcaacaa cagcgttgac aaagtacgaa
     3841 aaaaatagta ccatgatttt atcaatcttg aaaggagcta taagaatatg gcacaatgga
     3901 cgctaagagc gtgtcgagta aatgcaggtt ttactttgcg ccaagtggct aagaaggtca
     3961 acaagaattt tcagactatc tcaaagtacg aaaaagatag tacgctaatc ccttttgagc
     4021 tacttaaaga gttatcggaa ctgtatcagg taaaactgga cgatattttt taggagatag
     4081 tacgaaaaaa atagaactaa atcaaaagga aatctaagaa aggagcaaac caatggaatt
     4141 agtctacatg gacggtaaga aagagccgta tacactgagc agtattgttg cggagtgtgc
     4201 agaagttaag cacagacatt tgaagatttt gctgaataaa catcgagagg acttcgagag
     4261 tttcggaaag gtgcaattta aaatttcacc ttcagaaagt gggcaaaatg tacgggacta
     4321 tattttgaat gagcaacaag caaccttgct gatcacttac ttacgaaata cagaacccgt
     4381 aaaagagttt aagaagaacc tggtcaaagc attctttgaa atgcgtgagg agctttctaa
     4441 gttccgtatg cagagggcgc tagaaaagcc aaaaagaaaa accttgcatg acagtataga
     4501 gacatgggag gcaaaaccca agcacgcgca tagcaccatg aacaacctgc tactaaaagc
     4561 agtaactgac atgaacgcta agcagttaag ggaagaacgt gggggctata acggtattga
     4621 tagcttgacc agtgacgagc tggagcaata ccaggcattt gaggatatgg taatagccat
     4681 gatcggcttg aatatgagtt accaagaaat caaggctatg gcattcagaa ataaaaaaac
     4741 acgccaaaga agcgcgtgag agcaacaaaa aaggcttagc aataaccaca ccgcagagcc
     4801 tttcacacta acactaaaac gaatttaaca aagcaggcaa gctattatca aagaggtttt
     4861 agtaaagatt tatacctaga ttatagcata tttagggcaa tttgaccata cggagagcgc
     4921 caactcttta aactggtact ttctcatgct ctcaatttgg cgactcagag cgtgaggcta
     4981 tgaattgcaa gaaaaactgt ataagaaaca accattaaaa acccccacac tctcggtcgg
     5041 caaacttctg agcgtgagga tatccagtat agtaaaaggc attaaaagct cttagagcaa
     5101 ttacacaaca tagaaacaaa ggtaaaaaac atgacagaaa caacatacga gaatttaact
     5161 agacatatag acagaattag cgcagaaatg cgagaaattg gcgaaaaaaa tgggcttagt
     5221 agactttcat tattggcaaa tcagacaaaa ttcatcaaag aaaatttaca ccgtttactt
     5281 tggattgaac ttcctgaatt gaatgacagc cataaaatcg aggcagtttc taaaagcact
     5341 acgggaatgt ttttccacgc tggtattttt gaaatggacg ctatgcgaca agcattcttt
     5401 aaacgccaag ctatgcactt ttttgacaac gaagcagagc aacaggcgta tatagaacat
     5461 gctgaaaagg agtatttaga ggctactata accttaaaag atattctttt taactctaaa
     5521 aatggaactc agagagtaaa taaaagttgt cttatagaga agtttgagga ggcaatgcaa
     5581 tgacactaaa cctagacaac atgacacaag cagagtttga tgaagtaatg gctgaaatta
     5641 aggaaaaacg ccccaacctc ttccagttta ttgctgattt tgtagatcga aaagtaagca
     5701 ctgaggaggt agacgaatac ctgaagatga aacatgaaaa acaagtggaa tttatcaaga
     5761 attatcaagc gagggcataa catgaatgag ttagatttga ccaatacaca atcggtaatc
     5821 tttatggtgg tattgattgg cttactgctt tacctaaacc accgagaccg caaaaaaagc
     5881 gcccaatttg agcgagaaaa ccaacagagg atagaaacac ctagcgagga tttaagccct
     5941 gattatgggc gttatatcca gcttgcaggg gtaagagttt acggaggaac tgaatgagtc
     6001 tatcagagaa tgacaaacga gtattaagac taatcaaggt aggggctgag aactccataa
     6061 caggggcaga aatcagcctt ataactaagc tggcggaaag aaccgtacaa gatattatca
     6121 gccgtctaat cacgcgtcat agtgttccta ttgttggggt tcgccatggg acatttagag
     6181 gatattttat cccagctaac aaagaggagc tactggacgg agcaaaggca ttctataacc
     6241 aagtacagga agaacagaaa cgcctaactg tccttttgaa tgctgattta gagagttaca
     6301 aagaaacctt gaaggaggtg ggcggatatg tttagcctaa gccgagaaag tgagcaagac
     6361 ctagcgcatg gcattctgga ggtagtagaa agatacctgg aagcgcgtga tacagtcaag
     6421 ccacgactga caggtttaat atcagcccag gaagtcatgg acgagttaga tataaaatac
     6481 atgacactcc aaaagtggga aaaagcaggg ctaagacggt atcagccacc gctagaagat
     6541 actaggaaaa tctattataa aatatctgac atctggaagt ttttgggggt ggaaaatggc
     6601 aaggtatagt attcatccgg cagataataa agggcattat cacaatatta aattttacaa
     6661 agagcgcagg ccaaccctag accagctaaa ggaacagcaa aggcttaaaa agatgaagaa
     6721 aaaacgcaaa aaggggcgat agtatgacaa tttatgaggc taaaggcttt cagagtaatc
     6781 ttgtctatcc atttgataaa attgagcctt tccagtatat tgaacgattc aagcccttag
     6841 tagttcctga aggggcagat attgaggaat acaagcgaac tcaagcgcct tactgtataa
     6901 gtggcaaagt gacgccagaa aagcatggca gttacaagcg aaacaactcc agtctaatct
     6961 atcgggattt gattttcctt gattatgacg atatacaggg gacgtctgag ggctttataa
     7021 aagccatttc tagcgcttta tttggctact cttacatctt atacccgact atcaaacata
     7081 gcttagaaaa gccccgtttt cgccttgtag tgaagcctga caacgtgatg aatgaggcga
     7141 cctataagca ggtagtgaaa gagattgctg acaagattgg actccccttt gatatggcca
     7201 gtttaacatg gtcacaactc caagggctac cagtcacaac aggcgaccca gcaagttatc
     7261 aaaagattgt agagcatgga cttgattatc cagtaccaca gacaacggct gaaccagtca
     7321 aacagaatgc ggcaagcctt ccatacactc caaggccaag cgggcagaaa tctatgacca
     7381 tgaggatcat tgacacgctt ttcaacggat ttggagacga gggagggcgc aacgtagcac
     7441 tgacacgatt tgtaggctta ctctttaata agtgggttga ttgtgaccta gagacagcct
     7501 atgaacttac aaagatagcc aatagcgtga cagttgaacc attgccgatt gaggagctag
     7561 accgcacttt tagcagtata gcacgggctg aatatagaaa gagaggttag aaccatagaa
     7621 ctagaagaat tagcaaacct aaaaagtgaa atcttggagg taatggagca agaacaccct
     7681 cctagaacga tgaaggagct tgaaaatcgt atctttaaag ctggagaaga atggcgggca
     7741 gaacatactg aaactaaggt aaatgagaac acaggggacg ttaccgaaaa ggttgccatg
     7801 ccccaaacct tcacagtagc taaaatactg agcgagattg tcacatttac ttttatcagc
     7861 aagagcaata tacctgatta tagcctactc tatatctatg atttagacga gggtatctat
     7921 accgctagta atgatctatt caatcttttg tgtaagacct ttgacgttag aattaaaccc
     7981 agagagtggc cacagattaa gttaatggtt agaacattgg caaagatacg aaaaccttta
     8041 gaaagtgcta acctcattcc cgtacagaac ggcattatca acttagaaac taaggaacta
     8101 ctccccttta gtcctaagta tgtaattaca agtaagataa gcacggccta ccacgcgcct
     8161 aaacgagtcc caacagatag agagggaaaa acttttgatg attggttgaa ctcaatcgct
     8221 tgtaatgata gtgaactggt aacactgttt tggcagatta tccttgaagc tattaaccct
     8281 aaccatactc gaaataagtt tgctatcttc tacggggacg gtaacaatgg taaagggaca
     8341 tttcagcgct tccttatcaa cctgataggg gaaagcaata tatcagcctt aaagcctgca
     8401 cagtttgctg aaaagcataa cttggagacc ttggtaggta aggtttgtaa tattggggat
     8461 gaagcaccta acgaatactt aaaaaatccg tctgatttaa tgagtatcac tagtggcgac
     8521 actgttctag tcaatccaaa aggacgccca gcctttgaag ctactttcaa gttattcaat
     8581 atcttttcag ggaattatat ccccaatggt ggcaacaaga caaaaggctg gtatcgtaga
     8641 attatgattg tcccttttaa tgctgacttt aacggggaga aggaaaaacc ttggataaaa
     8701 aatgagtttt tagcaaacaa ggaagtccta gaatatgccc tctacaaagc tatcaatcaa
     8761 gagccattta ctcactttat cgaacctaaa gcagttaaag gactcctaga agaataccag
     8821 gaagataatg actacttact ttcatgggtt aagcatgaat acatggaaaa aggttggcat
     8881 gagctggacg tagtacctgt ttttatcgtt acaagatcac taaagcacta tgccgaagat
     8941 atgggaatac ccaagcccaa tgtttacggg gctggtaaag aaactatcaa gcacttacaa
     9001 cagttgacac ctaatcggta ttctctaaga aagaaaagag tttctccaga agattttgaa
     9061 aaactagagg catgggacgt tgacaagata aaaatgcgga cacctcaaca ctctatcact
     9121 aaacaagaat aagtgtgacg ttcttttttt gcttaaaccc ttgataatac tgattttctt
     9181 gaaaaaagtg tgacgttgtg tgacgttctc aaaaaagaag gtcacacccc ttgaagcctt
     9241 gatatatcta actttagggg aataggtgtg acgttgtgac attctttcca actcttatat
     9301 atagagaaaa atacagtatt tatatatata ggaacgataa aacaaaagaa cgtcacaggg
     9361 tcacaggggt ggtgaaacac ctagagcctc aagggtttga acgtgtgacg ttctttgtca
     9421 caaaaggtca cagaaggtca cagaaaacga aaaatattac ataatttacc ttaaaacaaa
     9481 gaaatgacaa caacatgaaa gttaaactat ttgaatatac tagacgatgg gaaaaagaag
     9541 actttgagaa agagatcgat gacttcatgg caactgttga agtgctggac gttaaatttt
     9601 ctggtacacc atctagtgaa tcctttaatt cggtggctat cgtattggta ttatacagat
     9661 aacaaaatgg ggtagatagt accgaccccc ttgcaatggt gtaactacta gtgacaccct
     9721 taaaaacaga aagaggaaaa acaacatgac attaaaaaca ttttcatcta aagccaaaac
     9781 atttactttc acttacgaat ttaaagacct agatacagct ctggtagcag gtcacgcgtt
     9841 actgggatat atgactggaa catattgcca gcctgtaatc tcattgacct acaaggataa
     9901 aggcacgcta gtagctgagt atgtggaaga tcacaagcta aacaagacct ttaagcgtat
     9961 ttgtgacagt tttaaagact accacaaaca accaggagag gctgaagcat ttgaagaacg
    10021 ttacaaacgg gagcgcgtgc tccaactcaa agagtcagag gactttgaga gtttactgaa
    10081 taaggtcaca gactacgagc tggaactatt agactatgct gaccgcctgc tttctgataa
    10141 gcctatccct atggactcta tgactgcttt tgctacgttg gaaatgctgg gcgatgaaag
    10201 tattagccta ctccaaaagt tggacgtaga gggcgaatat aaaggccttg ctggttatac
    10261 agagcatttg aagtagaata caggggagca atcccctttt tgctatcaag tcaatagttt
    10321 tgggtttttc catatagggg gaaataatga agcagttagc aatagaagca atcactaaac
    10381 caatgaagct gagaggaata tctaagggta tagccgagtt ggatggtcaa cgtttagaga
    10441 ttgatttgga tagtttaatg attgattttg gtggagagtc atttgaatta gacagaatag
    10501 caggaactaa gggaggtaat cgatattttt ttctttgccc tgattgtggt agacggtgca
    10561 ggttgcttta taaacggtat ttgtatttta gttgcggtac ttgtctagat atccacaagc
    10621 acaccctgaa ccgcagtaaa acggattgcc aatactactg ggagcttgca ctaaaagaag
    10681 ctagaaaggt agaaccaggg tggagtccta gacgtggcgg atatatgttt gatagttttc
    10741 ctgaaagacc aaaatacatg aaacagaaac gatattacaa gcattatcaa aagtttatta
    10801 actacaccag aaaaggggat agcttttggc tgaatggttt gagttctcta aggtaatttg
    10861 tagtagtgtg caatttacaa aacaaacaaa tactacatat tagacggttt gaatgttaaa
    10921 aaagctagat atatcaagga tttaattaag tatagcgttc caaaaaaagg gtgcagtaag
    10981 cgttccaaaa aagggtgagg taagggtgag gttgaatatt taaaaaaggc taagattagg
    11041 ctaaggtcac atacttcaaa atagcaaggt tttagcaagg tacagggctt ttttctagtg
    11101 atagaacccc aaggttacca caaggtatag ctactttttt agaaccatag aacggtaagg
    11161 ttacggtaag gtatcgaagt tttccaatgg taaggttttg gtaaggtagc atatataaaa
    11221 agtacaaggt tagtacaagg ttacatactt aaaaatacta aggttttaca aaggtagaga
    11281 ggtttaccga gggttagaaa aggtgagatt ttgcttaggt agtggcagta aatatgcctg
    11341 acaaatggca gggttatgtg tgttgaactc cgagcgaacg ccgagaaagt ggctatatcc
    11401 cccctatcat ttatcaagta gataagagca ataaaaaccc tccttaaccc cctgagaaac
    11461 gacaagcaga taagagaagt ttttagccct cttatttcgg atctactcct tgcagaatga
    11521 caagcagata aggacgacaa taagccttct taactgctta caaaacgata gggagttaag
    11581 acgaatttaa aagcccctta ttttcgtttt tctccttgtc aaacgggaag gaaataagac
    11641 aggaaataac atcgcttatt ttgattttgc tccctgaaaa actgtaagga gataaggaga
    11701 cttattagct tccttaattt gaattttctc cttacaaaat gacagggaaa taagaactaa
    11761 aataactccc cttattttcc taccaaatga taaggagata agagcagttt aaaagtctgt
    11821 tattttggat ttgttgctta caaaatgata agcagataag caaagaaata acttgcctta
    11881 attgcttgca gaatgacaag gaaataagag agataaaaac atcccttaat tgcttatcaa
    11941 atggtatgga gaatggactt gaacctagag cgaagctaga gaaaatgaaa aaaagccagc
    12001 acagggctga ctcctttatg aattattcca taaaactatt atatcacaaa ggaggccgag
    12061 gcatgacacc agagcaagta aaagaaaaac tagagggcgt taagtggata aacaaggaga
    12121 tcaaaggctt atatttggaa ttggaaaccc tggaaggtgg cattatcaaa aaaccaacac
    12181 taagccatag cagggtgcag acaagtagag agaataagac agagaacaat cttataagtg
    12241 ttctgaagct aaaagaggac actttacaga gaattgagcg acttactgaa gagagaatga
    12301 aaatatctga gctaatcgat aaactggcca atccgcttga gcgttctgtt ctaagacttt
    12361 tttacttgaa tgatcttgta gtttcggagg tggctgaaga aatagataga tcaaatacta
    12421 cagtatacat tataaggcaa aaagctatag aacacttaac aggtattgta aacggggatt
    12481 gatttaacct taccacggaa ttaggagagt atgggggagt cctaagccac atattcgccc
    12541 gtatttcgct ttgtttcgta ctggacaact aaaacaccat ggataaacta caaaccctca
    12601 gaaacgaatc tgggggcttt tgtgaggtca taatcttata aaccacgcgc ttcatggtat
    12661 aatatatcta tcagcaacca gcaataaaaa agcacgtttg accgtgctag tttcttgcct
    12721 gctgaactcg tcaaatctta gcccttttgt ggggcttttt tgctcccctt tttgcgtact
    12781 ttgggggagc aagtagtaaa aagtaatgtt agtaattttt attaaaaagc gcgtgatata
    12841 agggttagga agccctaagg aaacataaaa taagcgattg t
//
LOCUS       DAVDHC010000050        11460 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVDHC010000050 DAVDHC010000000
VERSION     DAVDHC010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.050"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..221
                     /locus_tag="VUR43_002043"
     CDS             <1..221
                     /locus_tag="VUR43_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5413670.1"
                     /translation="WENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQKIRHYK
                     VEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            224..778
                     /locus_tag="VUR43_002044"
     CDS             224..778
                     /locus_tag="VUR43_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5413671.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGASLIS
                     FLWMYGQRKQAHKVNMKSRIKWLGIGFVSLLIISLCFSLIHAQGSTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTCVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLV"
     gene            1013..1150
                     /locus_tag="VUR43_002045"
     CDS             1013..1150
                     /locus_tag="VUR43_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET5413672.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            1329..3938
                     /locus_tag="VUR43_002046"
     CDS             1329..3938
                     /locus_tag="VUR43_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET5413673.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIKSEQDIQDFIIKLLRGFTLTYG
                     QWHKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            3971..5911
                     /locus_tag="VUR43_002047"
     CDS             3971..5911
                     /locus_tag="VUR43_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET5413674.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEKLFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            5908..7515
                     /locus_tag="VUR43_002048"
     CDS             5908..7515
                     /locus_tag="VUR43_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5413675.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLFSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFVDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            7530..8270
                     /locus_tag="VUR43_002049"
     CDS             7530..8270
                     /locus_tag="VUR43_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET5413676.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            8273..9592
                     /locus_tag="VUR43_002050"
     CDS             8273..9592
                     /locus_tag="VUR43_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET5413677.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYCKSY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDILIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
     gene            9725..9862
                     /locus_tag="VUR43_002051"
     CDS             9725..9862
                     /locus_tag="VUR43_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HET5413678.1"
                     /translation="MAAEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            10658..10876
                     /locus_tag="VUR43_002052"
                     /pseudo
     CDS             10658..10876
                     /locus_tag="VUR43_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11176..11460)
                     /locus_tag="VUR43_002053"
                     /pseudo
     CDS             complement(11176..11460)
                     /locus_tag="VUR43_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3893 a         1460 c         2178 g         3929 t
ORIGIN      
        1 tttgggagaa cttgtccatt attttagctg aaagaaatat cagctggatt gagttaacca
       61 gaaaaatgtt tgcgggagag tttcactatc caagtgaatt gaatcgtttg tatcaaaaaa
      121 ttcgccacta caaggtggaa caacgaatgc ctcaaagtcc atgggtagaa aggattgtgc
      181 aggtattaga tttagattat gaagatttat ttcggaggta actatgaaaa gaataattcc
      241 agtttatata ttccaacaag taaatgtcct attggtatct ctatacttat tgaaatttct
      301 ttgtatcggt gagttaacta tactacagat tctctatggt gcgtcgctca tttctttttt
      361 atggatgtat ggtcaacgta aacaagctca taaggtcaat atgaaatcta ggataaaatg
      421 gcttggtatt ggattcgtta gcttactgat tataagtcta tgttttagtc tgattcatgc
      481 tcaaggaagc acgaatcaag caaacttaat tggccttcaa catcaagttc cttggttttc
      541 atttttattg ttcttaatca atgcgagtat ggttgaagaa tttctgtatc gagaaatttt
      601 atggaacttg gttagaaaat tagatattcg agttgcgttg acatgtgttt tgttcgcctt
      661 agctcatcat ccaggtacca ttctagcttg gtgtttgtat gtttcacttg ggatgttttt
      721 aggtatggtg cgctataaat ctgacttatg gggcagtatg ggactacatt tggtgtgaaa
      781 cctactagtt tatagtttga tgctttttta aaataggtga cctgattttt aggtaacttc
      841 taaaactaac ttccagtttt gggagagaga tggaagttac tttgaaaagt tacggaaaca
      901 ttattttcta tgtgacaaca ttgtataatt gcttgcattt tactggtgga gagagtataa
      961 tgagggtgga taaagtactt aatcccaaaa atttaaatag gaggagctag ctatggcaga
     1021 agaagtatta aatcttcaat tagtatctgt tcaagttgac gaaacagatg aagttgatgg
     1081 aatgcgattt agtacattca gtacaaatcg ttgcggtaac tggagtgctt ttagttggga
     1141 aaattgttaa ttcatttaaa ttgtaaactt tagagattct ctggagttat ggatgtcgtt
     1201 ccaatatgtg cacgttggaa tgttagtgct tatatgggga gaatccaaag gattctccct
     1261 ttttatttaa ataagtctgt ctagctatag atatattaag tttgataaaa tttcttggag
     1321 attttgttat ggattataat ttcaatttgg agcatccttt ctttttcact aataatgatt
     1381 atagtacaga tactagcata aagtaccaag taagtctgcc ttttaattgg cacgaagtaa
     1441 tgaataatga tgagtgggtt tatcaatacc ctattggaaa atttgttgaa agacaagggt
     1501 ggaaaataca cattagttca gagtataaca gttcacatga attgttacaa gatgtagcaa
     1561 aaatttgcca tgaaatgcga attccattta aacatcttag tacagaagac aaatttatca
     1621 tgcgaaacgg gaaattggtt agtcgaggat tttctggtaa atttattaca tgttatccaa
     1681 atcaaaatga attagagtcg gttttgcaaa ggttagaaag tgccttaaag caatataatg
     1741 ggccatatat tttaagcgat aaacgttggg atgaagcacc aatatatctg aggtatggtg
     1801 tgtttaggcc gtcaagggat gatgaaaaga aggttgctat tgatgaatta attgttggcg
     1861 atgaagttgt taaagatgaa cgtttaccag tatttaaaat tccaaaaggt atagtgcccc
     1921 ctgacttttt gaataaatgg cttgacaaga aagataaaaa acagggagac tttcccttta
     1981 ttatagataa tgcaattaga ttttcaaaca gtggtgggat atataatgct aggctaaaag
     2041 aagatgggaa aaaaataatt ttaaaagagg ctagaccgta tacaggtcta ggatttgatg
     2101 gtacttattc ttcagagaaa ttagcttcgg agtgcaaagc actaaaaatt ctaaatgaat
     2161 ggagtgagac gcctaaaata tactggcacg gtaagatctg ggagcacacc ttcttaggaa
     2221 ttgaacatat gaagggcgtt ccactaaata gatgggttac caataatttt cctttatatg
     2281 aagttgttga taagaccaaa gattatctat tgagagtttc aaagatagta gaaaaactca
     2341 tcgatttaac gaataagttt cattctgaaa atgtatatca tcaagattta catttaggaa
     2401 atatcttggt taaggatgaa gatgagatta gtataataga ctgggaacag gctgtctttt
     2461 caaatgatga aaaagttgta cataaagttg cagcccctgg ttttagagca tggcgagaaa
     2521 cacttcccag tgagatagat tggtatggta ttagacaaat agctcattat ttatacatgc
     2581 cactagtaac tacatcggat ttgacataca actatgtaag tcaaaccagg atagaaggaa
     2641 aaaaactatt tgagtctttg ggttatacaa gagaacatat agattatgta gaaagtttat
     2701 tgtcatatct agattctaaa tgtccacaga ttgagaatat ttccaggaaa aaagttttaa
     2761 aacccatgca tgagattaga actatcaaga gtgagcaaga tatacaagat tttattataa
     2821 aattattgag agggtttacg ctaacttatg gacagtggca taaagaattt caatcaagat
     2881 tcttcccagt tcattattat ggtctgaatt ttaatcaagg aattgcgttt tcagatttag
     2941 ctatcctttg gagttatcaa caactagcta agaaagtaaa aaatttcaag tttgatgact
     3001 attatgagat tcgaacacag gttattaatg aggcagtaaa taattttaag aaatcgtccc
     3061 tttctggtct ttttgatggt aaaattggta caatctggct catttatgaa tttggggaga
     3121 tagatcgggc agttgaactt tttacaactc attttataga gatatttgag aattcacaaa
     3181 ataaaaattt atatagtggg caggctggaa ttttactggt tggactgtat tttcttagta
     3241 aaggggaaat tgataataaa ctaggagaag aaatactaat taggcttaga gaatatactt
     3301 taaattatat agaaaatcca gaaacttttt gtaaagttgg cgctagtgat gttcagagta
     3361 atgatcctta tgagaatttt ggtggattac tatatggtca cgcaggggta gcttggctct
     3421 tcggtgaagc ttataaatta actggtgaaa gtatctataa aaatggtcta gaattggctg
     3481 tagataaaga attagttgct tataaagtag atagtaataa ttcattgcag tacagccaag
     3541 gtcatagatt actaccatat ctagcaactg gaagtgctgg cctgctttta cttattaata
     3601 gaaataaaga aatcttgtca agcaaatact taaaatattt aacttcttta gagagggcaa
     3661 ctgatgtagt tttttgtgta ttaccaggtt tatttaacgg attttgtggt cttgaagttg
     3721 ctaataatat atatagtgat atcgatgata acttttcagg acaaaagaaa ttaattgaac
     3781 aactttatag atatttgtgt gtaattgaag aaggatttgt tattgcggga gataatggtt
     3841 taaagataac aacagatatt gcttcgggat ttgcgggtgt tgcaattgga ttggtatcaa
     3901 taatggataa taaattgacg attcttcctc aaatataata tttagatacc attattaagg
     3961 ggtcatactt gtgaatcaga gtaatgaaat atttttaaat acaatacagg aaaaaacaca
     4021 ctataagagg tctatctctt catcatttca ggaattaaaa aaatggaatt ctttgatatt
     4081 taggagaggg cgatattggt accaatttga taattggagt atacccaata ctggtgtaat
     4141 aaaggaatgg tatgtcgaag ataatgactg gattcctaag gttagttctt ccagtttaga
     4201 caattcaaat tcacttaaaa ttgtctttga tgtggaaaaa tatactttgc cagatgatag
     4261 tatcttacag gatgttagga tttcatctga tgagagttat atagttttgg ttgtatcctc
     4321 actgcgtagc actaatttaa ttggaataaa aaaatatact atggagaagt tatttatcat
     4381 tgaagatatt tcagtagaaa gttcgttcta tttgggtaaa ttcggtgtta tgtatactcg
     4441 ctccaaagag tacgggaggc caagtaagtt attctataaa tcttttgata gctttacaga
     4501 agaggaactg tttgaagaaa acgaatgctc ttttcgatta aaaatagtcc acattgatag
     4561 caataattgt tttgtaaagt cagtagactt tcagaaaggc aggatttttc tatacagttt
     4621 cgaccggacg ggttttgtta gacactctta cacagaaacg gtagccccaa cacctagaga
     4681 tatcgctcta tttagtacag aaaaagcaca gtactttctt gggctctctt caactgaaga
     4741 aaagaaagat caactaattc taagggaaac ttcttcggga gacagagttt ctattactat
     4801 accatatcaa gatagggcta gaagagttca ctgtatagga cgttatatcc ttttagactg
     4861 ttcaaacgca gcgaattccg tcttttatct tgctacattt aaaaataata gtttgaggga
     4921 gttgagtgtt aataagataa catttgatga aaagacaaca ctttatgaaa attcattttc
     4981 tgatcgtgtt cttctgtttt tagagaggag aactttttac gaaaaaatac ttagttttga
     5041 tttaatagaa aatacattaa aaactgaatt tgaaagaccc atcataaaat cgaataatac
     5101 taaatatttt tctaaggtga tttggactaa aaaagatagt tatgatgtaa gcataccgat
     5161 ttctttattt tggaaaagtg aagatacgga tgagctccca agaagaaaaa aatgtattct
     5221 aagtgtctat ggggcttatg gtaagaatga taattctgat ttagatgaaa ttatgttatc
     5281 tataatagat gcaggtttta tttatgctat agttcatgta agaggtggag gctatttggg
     5341 tggtgaatgg tatcgctcag gaaaggcgtt aaacaaatgg aattctatca gagattttat
     5401 tgagggagta aattatttaa gggaaaatga tgtaattgac agtaagcgat taggtttaat
     5461 aacttctagt gcaggtggaa taattgctgg tgcggtgttg aacgaggaaa aaaatttatt
     5521 gcaaagcatt ctcttatttt cgccatttat aaatccttat gatacacttc agaatccaaa
     5581 tgatcctctt tctaagaccg aaatagcaga gtggggagat attagagacc ctgaagtaaa
     5641 ggcttatata aagtcatatt cgcctatgca aaatattgaa aaggcacgag actcaaatac
     5701 tgttatagtt aatattttgg gtgagaaaga cccatatatt aataataacg aagtgataga
     5761 gtggtcaaag aaattaaatt ctattggagt taaaagtttg ttgtatttaa acaaagcagc
     5821 tggtcatgga ggttttactc catcagatgt tctcttaatg attgatactt taaattattt
     5881 ctttgaagaa gtgggaagga ataacttatg aattatttaa aatttataaa aaagactaaa
     5941 cttatattaa tggggatttt aatatttcta tcttcgttta atggtgtctt gctctcagga
     6001 attattgtat atgcaggtag tttaaatcag acttcctcat tttctgacgt tctaagattt
     6061 ggtgctataa gtattctggg ttggtcagca atctatatat caaattacta tttagaagta
     6121 acggaagcat caataacgaa agatataaat gtaaaaatta aacaaggata ttttagagaa
     6181 cagtatcttt tttctgaaat ggttaaagat tactcatcta ttatttcagt tttgtcaaat
     6241 gatttgagat taatcgaaga aaactatttt agacaaattt ttgaaataat ttcttcaata
     6301 ttgttgttca tcgtctctct aagttttatg ctttatttaa acttcctagt ttcaataata
     6361 tttattgtat tatcagcatt gccgattata gtacctgtct ttatgaagaa gatgttgtct
     6421 aattcagcta atgagtactc taacagcaat gcagagtata ctcacataat aaaagaaatt
     6481 tttaatggtt ttaagacatt aaaatcttat tctgttacta aagaaataat tagtttgtcg
     6541 gataaaaagt tggataaact agaagattct acttttaatt tgaaacgatc agaggttctt
     6601 tcaaaattgg ttgcagtact aatttcaggt ttttgctttc tagttccctt ggttgtagga
     6661 tgttattttg taatttatca taaaagcctt tcttttagtg aactgatagg tattttctta
     6721 gcaaacgata aagttttagg gccgatacaa tcaattgcct attcattaaa taagataaat
     6781 acaaccaaag atttaaggaa accgttttta aaatacttaa gtggagagaa gaattttgta
     6841 gacgctgaac atgataataa cggactgtat acttcatcaa tagatgagat acacatgaaa
     6901 gatgttgtat attctattac accagaaaat aaattaagta ttgacttctc atttaagtca
     6961 ccatttaggg tattattaac aggaacttct ggcagtggga aaacaacgat tttaaattta
     7021 attaatggtt ctttaaagcc acaaaaaggt tatgtaaatt tgttatcaca tgggaaaaag
     7081 agttcagatt caataccaac agttgatcag acaccatata tttttgacac tactattcgt
     7141 gagaacgtaa ctttatttca aaatgaatat ttttcagatg atcagataat tgaggtgtta
     7201 aaaaaggtaa atctatatga agaattagaa aagatagata tactaaatta tcaatgtggt
     7261 gaaaatggta gtaatttgtc tggaggtcaa aaacaaaaaa tagctttagc tagagctctg
     7321 attagaaata ataaagtgta cttatttgac gaaatatcag ctaatttaga taatgataat
     7381 tcaaattcca tacatgatat tctgttcaat ttaggtattt catttattga agtttcacat
     7441 cattatgact taaatgacaa gagatacact gatatatata aattggaaaa tggaacactt
     7501 ttcaaaatta agtgattgga ggcaagaata tggataaaga ttatatatta aaagtgaaag
     7561 ggctgtatca tcaattttta ctaggaaata ataaaacgtt gcaagtgctg aaaaatgttt
     7621 ctctttctgc ttcgagagga gaatttataa gtattctagg aattagtggt tctggaaagt
     7681 caactttatt aaaatgtatt tctagtttgc ttgaaccaac aagtggggaa gtaattttaa
     7741 atggaatcaa cccctataaa atcagaaatg caaaattgtc aagtataaga cgtaacgaag
     7801 tatcttttat atttcaagca tacaatttaa taccttccct gccggtaata gaaaatatag
     7861 cacttccttt gcgattatca caaaaaaaat taactattaa aaatgtagaa aacttactca
     7921 aaagaatgaa gtttaatgct ggcttaaacg attttgttgg aactctgtct ggtggagaac
     7981 aacagaaggt tgctatagct agagcggtta ttgctgatag tgatataata tttgctgatg
     8041 agccaactgg ggctttagac agcgtttctc gtgaagtaat ttttgaatta ttgagagagt
     8101 tagtaggggc gggtaagtgt gtaattatgg taacgcacga tatagaattg gcctcgaaaa
     8161 ctgatcgtgc attaatattg aaagatggaa aaattttcaa agaacttcat agacctagcg
     8221 gggaagagtt gtataaaatc ttagaggtac aatcaactac ggaggaatag agatgctcag
     8281 attagtttac tatcaatttt tacataataa gaaacaatgg ttaggcgttt caccagtaat
     8341 ttttgtttcg agtttagtta tgggattggc tgttaatggg gtaattaatg ttgagaataa
     8401 ttcgcaagta tttgtcggac ttccagatcc taaaccaatt tttatgtttc cgatagtatt
     8461 cggaggagta acattattct ttgtgctctc taacataata aatatgttgg ttgaaatttt
     8521 tagagatgat tacgaacttc tggaggtgtt gggagcaagt cgccttcaac tatcatttct
     8581 tgtgggggga cagattttta tcatttcctc gattattagt tttattgcat atctatgctc
     8641 tatatttgtt acgtcaaatt attattattt tttacaatac tttttcgggg aaaatatatt
     8701 acctgatatc caatttcaaa cgagtgctgt tggatgtatc attacagtag tgttgatttc
     8761 atttttagcc tttctaagtg gttgctttta tacgttcaag aagattagaa ataggaagag
     8821 ttctaaaata aggcatgttc tttcaatagt aaaaagaata ctgctattgg ctggttttag
     8881 tgttatctgg ttgctttctt tgcaacaaat tttccaagat agcacaattt tagcgaaggc
     8941 ccagataata ttcaatattg taatcttaga tattgtgatt atttatcaat tatctccttt
     9001 tatacagtca tgttttatca aactactttc tataattata tttagaaata attttatgtt
     9061 cattgtttcg aagtggaatt tactatattg taagtcttat ataaaatcta tcagtgctgc
     9121 aattacagga gctatattac taatttctag ttttcaaatg atttctcaga atatactatc
     9181 tcaatttcaa gatgacagtg atttagagct aaaagtagca tttattgtct atgtaggagc
     9241 accaattttg atagtacttg caaatattat ttcaattgca tttttgtcat cgcatcaaga
     9301 aaggattgag attcagcaat ttgaaatttt aggaacttct aattaccaga tggttaagat
     9361 taaagttggt gaggctatat ttttgacatt tgttacttca ttaattgcat ttttacttaa
     9421 cattaaaatt atggctttaa tatactactc tttagaggat attttaatag atgatatgaa
     9481 tcttttgggg ttaatacttc caaattttat agtatctatt attttattta ttttaatatt
     9541 tattactaaa agttcctatt ttatctttaa gaatgcaaaa attatttctt aaaaatttgt
     9601 aagttttcgc tatataaaat agttaaatct attttgtatc attgcttgca ttttactggt
     9661 ggagagagta tatgagggtg gataaagtac ttaatcccaa aaatttaaat aggaggagct
     9721 agctatggca gcagaagtat taaatcttca attagtatct gttcaagttg acgaaacaga
     9781 tgaagttgat ggaatgcgat ttagtacatt cagtacaaac cgttgcggta actggagtgc
     9841 ttttagttgg gaaaattgtt aattcattta aattgtaaac tttagagatt ctctggagtt
     9901 atggatgtcg ttccaatatg tgcacgttgg aatgttagtg cttatatggg gggggaacag
     9961 aatcctctct tgattgaaga caagctagtc attaggctgg tttgtctttt tgtcaactgt
    10021 agtgggttga tataatagta ttagtgagtg ggataaaagt ttcatttagt ttattcagta
    10081 caaatttaac gggtcaagat ttatatactg gtggtgtttt tggggctgag agaagcatct
    10141 tgattttatg tgtggttttt atacttacag ttgttctgct ccaaagagct tgtagagaag
    10201 aattagctca taaaggagat tgattatttt gatatcaaaa aaatgcacag gataacctga
    10261 tgcatttttt tagcgacaat gcttgctact tccttctgtc gaatttagac aattttaaat
    10321 aaaagaatga aatattccct actgtatttt tagacgaaga acgttagtta ataatactca
    10381 aatttatttc aaactctttg attagtatga atttagctct acagaaaaat aaaaaatgtg
    10441 ataaaaattt caactactct tatctataat aaagctacct gttctttgaa aattgaatcc
    10501 actccgtctt gattagcgtg cctgtgtaag tagggactga gagtatttcc ctgtgaaggg
    10561 caactggcac aagacgtgtg tgagaatttt ctaacagaca cggagtttat cgtttccaga
    10621 ctcaaacgat gcgacaaact agataaagga gttaatcatg aaggtagtaa acttgtatga
    10681 tttgaaacaa atgggaaata aaggtggttg taccatccaa ttgattcatc actttccttt
    10741 tggtatgggc ttaggacatc tcaaaaaaga ctacattgaa tttaaacgtg ttggtatctt
    10801 tgatgggaaa gcagtagaag ttactcttcg agaaccttat tcgagagatc tacttcaggt
    10861 tgtcaagtca ataaagtaac tgacaccacg agtataatta ttagaaacgt ggaatcttat
    10921 taaattttat aataaatata ttaaatgaaa aattattaga tataaactta tgtaataaaa
    10981 cattgaggaa ataataaaaa tctatgggta atgttctgaa agtactttta ggttaggaga
    11041 gaaatataat gatttttgaa aattgattca aaaaatagcg aattgtagaa aacgcttaac
    11101 aaatggtgta taatagactt ccagcgaaac aaaatatgct acaataaacc tatgaattat
    11161 aaagcaacct tatactcatc tgtcttcaca aagcattcta gtccatctcc gattaacgat
    11221 ggactttatc atctccttct ccagtccttg tatgacatct tccaaagttc gaaaggcttt
    11281 attcttaaat ccacgtttac gaatctcttt ccacacttat tcaatggggt tcatctctgg
    11341 tgtgtatgga ggaataaatg caaagccaat attagtcgga atctttaagg cacttgattt
    11401 atgccatata gcattgtcca taacgagtaa aatataatca tctggataag cttgtgaaag
//
LOCUS       DAVDHC010000051        10938 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVDHC010000051 DAVDHC010000000
VERSION     DAVDHC010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.051"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            40..1269
                     /locus_tag="VUR43_002054"
     CDS             40..1269
                     /locus_tag="VUR43_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET5413679.1"
                     /translation="MGNPIKYNNTADGDIDELLTAFDGAEIDQVDAQNALNMAIYGRA
                     YEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPLFAVYYYEVKDDTKDTTKHQAEV
                     FTENLHYHMVLRSTDSGTIQSEEATPHNLGQIPIIEYRNNHFAIGDYEQQISLIDAYN
                     SLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAMKILSEEGLLELPGDSARAEFLK
                     NTLDESATEILRTALKEDIYTFSHVPNLTDENFAGNTSGVAMEFKLMGLEMITKTKEA
                     NYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRGLPKNLLEISQIVNNLEGKVTNR
                     QLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNKDNTKPEDEVEDEESGVLGEEESQ
                     SDLPADGQGRKAGRPVR"
     gene            1178..2815
                     /locus_tag="VUR43_002055"
     CDS             1178..2815
                     /locus_tag="VUR43_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HET5413680.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTDIWKNTGKLTSSIKDELLMSLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFAAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKTELVPADM
                     TYKEWYSKYVAKDGEKVYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKL
                     AGLEFRKKTVESLSRKIIADSLVENISLSKAVSKINDALRYTTIFDSDTFTEEYLKMK
                     QKLIAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHELY
                     EKYRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            2817..3026
                     /locus_tag="VUR43_002056"
     CDS             2817..3026
                     /locus_tag="VUR43_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413681.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            3023..3436
                     /locus_tag="VUR43_002057"
     CDS             3023..3436
                     /locus_tag="VUR43_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET5413682.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLFASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIYYLST"
     gene            3479..3742
                     /locus_tag="VUR43_002058"
     CDS             3479..3742
                     /locus_tag="VUR43_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413683.1"
                     /translation="MKYRKKPVVVEAVQFLDTEESIDELCDFGLDPVRIDYADLKNPL
                     LKIETLEGLMVATEGDYIIKGVQGEYYPCKPDIFAETYEKTEE"
     gene            3744..3995
                     /locus_tag="VUR43_002059"
     CDS             3744..3995
                     /locus_tag="VUR43_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413684.1"
                     /translation="MLEKAKQLASQEFLRLSGREIKAEDCFVVWFSKTLQNWKALVST
                     NAITSSEPCGDYAEITHNGDKNETYVDVYAKVSNRAIKD"
     gene            4222..4806
                     /locus_tag="VUR43_002060"
     CDS             4222..4806
                     /locus_tag="VUR43_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HET5413685.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDTVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            4812..5654
                     /locus_tag="VUR43_002061"
     CDS             4812..5654
                     /locus_tag="VUR43_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HET5413686.1"
                     /translation="MTAGQTKLATMVNPEVMADMVSAKLPKLIKFTPLAYVETALQGQ
                     PGNTLTVPAWEYAGDATEVGEGQAISPDQLTTKKTTMTIKKAAKGYEITDEALLSGLG
                     DPLGQATYQLGLAIANKIDDDLVAVAKTATQHITETPTTLAAIDKALEIFEDEEDAQY
                     VAIINPKDAIKLKTDVAKEWTKGSELGADMVVSGTFGEVAGVQIVRSKKVDEGKGFIV
                     KVSPSQTQTDDANKYGAFVIMLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGE"
     gene            5666..5848
                     /locus_tag="VUR43_002062"
     CDS             5666..5848
                     /locus_tag="VUR43_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HET5413687.1"
                     /translation="MSLLLRRHYIQEEQVSQYSDLENKTLEELKNLAKEAGIAGAYKL
                     SKAEIVEVLEDLKSEI"
     gene            5838..6026
                     /locus_tag="VUR43_002063"
     CDS             5838..6026
                     /locus_tag="VUR43_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413688.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGGELEITEERYVELADNIASNGVA
                     ISDVLEKILPEPEFLEED"
     gene            6028..6339
                     /locus_tag="VUR43_002064"
     CDS             6028..6339
                     /locus_tag="VUR43_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HET5413689.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIEVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            6320..6658
                     /locus_tag="VUR43_002065"
     CDS             6320..6658
                     /locus_tag="VUR43_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413690.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYVKEAETIRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTYHQVLE
                     LERVRATRGR"
     gene            6633..7148
                     /locus_tag="VUR43_002066"
     CDS             6633..7148
                     /locus_tag="VUR43_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET5413691.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            7145..7513
                     /locus_tag="VUR43_002067"
     CDS             7145..7513
                     /locus_tag="VUR43_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413692.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            7516..7929
                     /locus_tag="VUR43_002068"
     CDS             7516..7929
                     /locus_tag="VUR43_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET5413693.1"
                     /translation="MLANGITLSYGEAKGTYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVNFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELEFTDGVGG"
     gene            7934..8314
                     /locus_tag="VUR43_002069"
     CDS             7934..8314
                     /locus_tag="VUR43_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413694.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKNKKTSKKKMTVVE"
     gene            8353..8703
                     /locus_tag="VUR43_002070"
     CDS             8353..8703
                     /locus_tag="VUR43_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413695.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKTQERKEKIIDSYR
                     LSQMISNHVSLLLSNDAKIVEFWEYAPELFVEEQQAVELERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            8690..>10938
                     /locus_tag="VUR43_002071"
     CDS             8690..>10938
                     /locus_tag="VUR43_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413696.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSAAMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKT
                     ALDQIAKTMGEIVTDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERIIRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGG
                     LAGAFSLLG"
BASE COUNT         3517 a         1938 c         2619 g         2864 t
ORIGIN      
        1 catgccaagg atatcgcaga cacggctacg ggctatttta tgggcaatcc tatcaagtat
       61 aacaatactg ctgacggtga tatcgatgaa ctacttacag cctttgatgg tgctgagatt
      121 gaccaagtag atgctcagaa tgctttgaat atggctatct atggtcgtgc ttacgagtac
      181 atctatgcta aagagggtat ggctgagttg gattcaacta gtattgatcc ggagaatact
      241 ttcatggtct acgatgatag tattgagcgg aagcctttgt ttgcggtcta ttactatgaa
      301 gtaaaagacg atacgaaaga cactaccaag caccaggctg aggtctttac cgaaaatctg
      361 cactatcaca tggtgctgag aagtacagat tcaggaacaa ttcagagcga ggaggcaaca
      421 cctcacaacc ttggtcaaat cccaattatc gaatatcgca acaatcactt tgcaattggt
      481 gactatgagc aacaaattag cttgatagac gcttataatt ccttgatggg gaatcgtgtc
      541 aatgataagg aacaggctgt agagtctata cttgtcttgt atggcacgca gttagcagac
      601 actccagaag acgctaaggt agcaatgaag attctttctg aagaaggtct tttggaattg
      661 ccgggcgata gtgcaagggc tgagttcttg aagaatacgc tggacgaaag tgctactgaa
      721 atcttgcgta cagctcttaa agaggacatc tacacattta gccatgtgcc taatttgact
      781 gatgagaatt tcgcagggaa tacatcaggc gtagccatgg aatttaagct gatgggcctt
      841 gagatgatta ctaagaccaa ggaagcgaac tataagcgag gattgcgtca gcgtattgcg
      901 atttttgctc attacttagg catgaagcag attgctttag agtctcattc aatcgttcca
      961 caattcagtc gtggtttgcc taagaacttg ttagaaatct ctcagattgt gaacaatttg
     1021 gaaggcaaag tgaccaatag acagcttatt tctctcttgc cgtttgtgga agaccctgac
     1081 gctgagctgg aagccttgga agaagagaaa aagaagaaca tggaagacat gccgatgttc
     1141 aacaaagaca acacgaaacc cgaagacgag gtagaggatg aagaatcagg agtattgggc
     1201 gaagaggaaa gccaatctga tttaccagca gatggacaag gccgaaaagc aggcagacca
     1261 gttcgataag gtctatcagg aagccaagac ttacttggat aaggaagtca ataagatttt
     1321 tgataagttc caacgtgatt atggtctaag tcaggtagaa gctagacaag tcttgaagaa
     1381 catgaaagac aagaaaaatc tgaatgaact tcgtaaagta cttgaagcga gaccgaatga
     1441 cccgaacatc caaagattac tagctgactt agacagccca gcttattctt tccgtatgaa
     1501 gcgcctagag cgtttgagcg acgatttaga ccgtatgcgt gaatctatct atcattcaga
     1561 gaagacaggc tcagacgcct tttatagcga cttgatgaag gatagttact acaaggctac
     1621 ctttgacctg cagcagcaga caggactagc atacggcttt tctgggcttc ctgagagcga
     1681 gattaaacat ctacagtctt tcagttgggt aggtgacgga agtacctact ctacagacat
     1741 ctggaagaat acggggaagc ttacttctag cataaaagat gaactactta tgagcctcat
     1801 gacaggccga gatacacgag aaactgcaca agcaattgct gagaggttca atgtaggtca
     1861 gaacgatgca agacgtttgg ttcggacaga atcagccttt tttcataacc aaatggaact
     1921 actcagctat gaagaagcag acatagaaaa gtatatcttt gcggccgtct tagacaagcg
     1981 tacatcacgg atttgtcagg agcatgacaa tcaggtctat gatagggaca aggctgtccc
     2041 tggcgtcaat tgtccgccta tgcacccttg gtgtaggtct actactgtcg gatacgatga
     2101 ggacgcagat tacagcaagt tgaagcgcag agcaaggaat ccagagacag ggaagaccga
     2161 gctagtacct gctgatatga cttataaaga gtggtatagc aagtatgttg cgaaagacgg
     2221 ggaaaaggtg tataatcaag atacaagaga agccaaggcg aaattttata gcgaacaact
     2281 attgtccaaa atttcaggag ttgagccaaa aattacaagt gatatgcaac gtatcgcagg
     2341 agaaaacaaa ttggcaggtc ttgaatttag gaagaaaaca gttgagtcat tatcacgtaa
     2401 aattattgca gatagcctag ttgaaaatat aagtttgtca aaagccgtga gtaagattaa
     2461 tgacgcctta aggtacacaa ctattttcga ttccgatact tttacagaag agtatttgaa
     2521 gatgaaacag aagcttatcg cagaaggtta taaaattgta aaagtaaaaa acacttggct
     2581 agtagatgga ccatacaaag gtgtgaatac agtcgttgaa aaagatggta tcaactttga
     2641 aatgcagtat catactcagg aaagtttcga cttaaaaaat ggttcattac atgaactcta
     2701 tgagaagtat cgtgatacga atacatctga tctagaacgc atgaaattat ttaaggaaat
     2761 gcttgattta agcaatgggc ttgagattcc taaaaatata gagagggtga agtgatatga
     2821 aagatattaa atactaccgc acaacgacga acaatgctca agtacttcgt ttgattgatg
     2881 gtgtcatgca agtttttgac attgaaaaaa agtgggttaa tagcatggat tggtttaata
     2941 aaatcttttt taatgacttt acggattttg aagaaatttc agaaaatgat gcatttactt
     3001 atattgacag gatggtagcg gcatgattga tattgccttg gctatcgcta aaaaagcaca
     3061 tgcagggcag gtagataaag cgggtgttga ttacatacag catcctctct atgtggccag
     3121 tcaagtcaac actgaacaag aaaaagctgt cgctctttta catgatgtga ttgaggatag
     3181 cgatataact gctgccgatt tattcgcgtc tggcttgtca aatgaagttg ttacagcggt
     3241 acaaattttg acaaagaaaa aaggtcaaag ttatcaagaa tatcttggga aagtaaaatc
     3301 aaataattta gcaagagttg taaaacttgc agatttgaaa cataactcag atttatcacg
     3361 tttgaaatct gttaccaata cagactacga gcgtgttaaa aaatataaaa atgcaattta
     3421 ttacttaagc acctagagaa atctaagtgc ttttcttatg tttagaaagg agcgagaaat
     3481 gaaatatcgt aaaaagccag tagtagttga agccgtgcag tttttagata cagaagaatc
     3541 tatagatgag ctatgcgatt ttggattaga tccagtacgg attgattacg cagacttaaa
     3601 aaatcctctt ttaaaaatcg aaacgcttga aggattgatg gttgcaacag aaggtgacta
     3661 cattatcaaa ggcgtgcaag gagaatatta tccatgcaag ccggatattt ttgcagaaac
     3721 atacgaaaaa acggaggaat aaaatgttag aaaaagcaaa acaattggca tcgcaagaat
     3781 ttttacgctt atcaggtcgt gaaatcaaag cagaagactg ctttgtagtt tggtttagca
     3841 agaccctgca aaactggaaa gctcttgtta gtacgaacgc aattacatca agcgaacctt
     3901 gtggagatta tgcagaaatt acgcataacg gagataagaa tgagacttat gtggatgttt
     3961 acgccaaggt ttcaaatcgt gccattaaag attaggaggt gatccaacat cttgacttgc
     4021 aggaatagac tgctataaat tactgtaaat tgctataaac cgtgtcatat ttgatgcggt
     4081 tttcctatgc cctaaccgta tggaatcccg tacggttttt atattgtcca aactgtgccg
     4141 atgacattaa aagctgtact gttccgtcgc cggacgtaaa gcgagattat cgagtggcga
     4201 cgtaatcgct ggaggacaat tatgtcagaa gaaatcaatg caactgtatc tactgaatca
     4261 actgagaccg tcgacactca aggaaatgtt gatacagtgc aagaagaaaa gcacgaacga
     4321 actttcactc gtgctgaaat cggtaagatg ctatctgccg agcgctctaa atgggaagct
     4381 gagcaagaag ccaaggaaaa tgaagctaag aaacttgcca agatgaacgc tgacgagaaa
     4441 cagaaatatc agttggatca gcgtgagcaa gaactagctg accgtgaaaa ggctattgct
     4501 cgtaaagaat tgaccgcaga agctaaagca atgctaagtg aacgtgactt acctgttgag
     4561 ttagtgaacg tggttgattt gacaagcgca gagacggtat cgcagtctgt cgctgtattg
     4621 cagaaatcat gggagcaagc cgtgcaaaaa ggcgtacaag aaaagctaaa aggcggagcc
     4681 ccaatgaaac aagcgccagt cgatagtgac ggtatcacaa aagaagaatt tgctcgtatg
     4741 ggttatcaga gtcgaaatga actctatcaa aagaacccag aactctataa gaaattgaaa
     4801 ggttaaaata aatgacagca ggacaaacta aactagccac tatggttaac ccagaggtga
     4861 tggcggacat ggtttccgct aaactaccta aattgattaa atttactcca cttgcttatg
     4921 tggaaacagc actccaagga caaccaggga atactctaac agttccagca tgggagtatg
     4981 caggagatgc gactgaggtt ggagaaggtc aagctatttc tccagaccaa ttgactacta
     5041 aaaagaccac tatgaccatc aaaaaggctg ctaaaggtta tgaaattacc gatgaagctc
     5101 ttttgtcagg tcttggcgac ccactaggtc aagctactta tcagcttggt ttggctattg
     5161 ctaacaagat tgatgatgat ttggtcgcag tagctaaaac tgcaacacaa catattacag
     5221 aaactcctac aactcttgca gcaattgata aagctcttga gatttttgag gacgaagaag
     5281 atgcgcaata tgttgctatc atcaacccta aagatgctat caagctaaaa actgacgtag
     5341 caaaagaatg gactaaaggt tcagagcttg gtgcagatat ggttgtatcc ggaacgttcg
     5401 gtgaagttgc cggtgtgcaa atcgtccgtt ctaaaaaagt tgatgaaggt aaaggcttta
     5461 tcgtcaaagt ctctcctagc caaactcaga cagacgatgc caacaaatat ggtgcgtttg
     5521 ttatcatgct aaaacgtgat gtggctatcg aaacagaccg tgacatcctt aaaaagacaa
     5581 cggttatcac tggcgatgaa cactatggtg tttacctata cgaccctaca cgagttgtaa
     5641 aattcggtga gtaagaggtg acgatatgag cttattgcta cgacgtcatt atatccaaga
     5701 ggagcaggtt agccagtatt ctgatttaga gaataagact ctagaagagt tgaagaatct
     5761 agccaaagaa gctggcatag ctggcgccta taagttatca aaagccgaaa ttgtagaggt
     5821 gctggaggat ttaaaaagtg aaatttaaaa tcaaacaaga tttctatgat tgggaatcaa
     5881 atgtgaaacg actggcagga ggggaacttg agattactga ggagcgctat gttgagctgg
     5941 ctgacaatat tgccagcaac ggtgtcgcta tctcagatgt tcttgagaaa atcctccctg
     6001 aacctgagtt cttagaagag gattgatatg tctatagagt tgctgaagaa attaacaggc
     6061 gaagaagata ctcagcttct catgttgctc caaacaaggg ctacaaatct tatcttgtca
     6121 gagactaatc gcacatcttt gacacctgct ttaagtcttt taatacctga ggttgctatc
     6181 gagctccaca accgctcagg agcggaagga gagcgttcta gaaccgaagg tggtatagaa
     6241 gtagtctacg gagaaaacgg cctgtctacg ggccttttac agcgtatacg tatgcataga
     6301 ctagcaaggg tggcaggcca tgtttttgaa gcagagtaga ctgaaacctt atccaatgcg
     6361 acggtttgaa aagactgtca ctgaggaagg tgtcgcaaaa gaaggatatg tcaaggaagc
     6421 tgagacaatc cgtcttgagt tgtggccagc tagtagtaaa ctacagtctg aattgtatgg
     6481 cgagcgtgtc aatgatattt tgaacgcaaa tgccaacaag tcagctacaa tcaaagtgaa
     6541 agatggtgtg tgtatcgata gccagacaga agtgactcac agggttattt ctaaaaaggt
     6601 ctacacatat catcaagttt tggagttaga gcgtgtcagg gctactaggg gcagataggc
     6661 tcatagctaa atgtagacga ttggctagta aaaaaactgg agaggatatc gtcttacgtg
     6721 cggtacacaa tgctactata aaggttgtcc aagcagatgc aagaagactc gcaccagcga
     6781 gagatggaga gcttataact agtatcaaaa ctagggcaaa aatggacgga gataaggcta
     6841 taggcgaggt ttacaccaat cttaaatacg ctccttacgt tgagtttggg acagggccaa
     6901 taggacaagc tagccattcg ggtatctctc cagaggtcag cgtcacttat aagtctagtc
     6961 cgtggtatgt gcatgaagac caaatcaatg taggacctta ccattttcaa aaaattgggg
     7021 agttctacaa gatgtatggt caacctgccc agccttatct ttatccagct ttgagagaca
     7081 atcaagagcg tgtgtctaag aatatttcga attatgtccg tagaaagata agagaacaaa
     7141 taaaatgatt aatatcaagc ctgttattta taaagaattg caaaaggtcg cagataatgt
     7201 gactgatact tatcctagcg attgggagac tttcccagtc gttatttttt tagaagaaca
     7261 aaacaagccg ggtgattggt ttgatgacca ggaacaaaaa tcatctatcc gctataaggt
     7321 ggatatcttt gatgatacca gcactagtga gttagctgtt aaaatcaatc agatttttga
     7381 gtctttaggt ttgcgaagaa ccgactgcca agacgtgcca gacccgtctc atttgagaca
     7441 taaggtcatg cgctttgaag gtgtcgttga tttagactca gagcttgttt ttcaatttag
     7501 aatggagaat taaacatgtt agcaaatgga attacgctat cttatggcga agctaaagga
     7561 acttatacta aacttgttgg attgaaagaa gtgccagagt ttggtattga actcgaaaaa
     7621 gtagaaaata ctactcttga agatacagtg aagaagtacg agtttggtat tggggacata
     7681 ggagaacttg agtacaagtt ctcttataat aattcaagcg caactgctcc ttatcgtgta
     7741 ttgcgtaagg cagcagacga caagaagaaa ctctacttcg agcaagcata cccagacggt
     7801 actaaggtca attttgaagg ccaagtatct gttaagcttg gcggtggcgg tgtcaatgcc
     7861 gttatcgagt tcacacttaa gattgccttg cagtcagagt tggaatttac agacggtgtt
     7921 ggaggttaat taaatggcgt taaaatacac aacttggaaa gttactgacg aaaaagagtt
     7981 gaagctacgt ttgacatctc atcaagctgc aactgtggaa gaaaaaatcg gcatgaactt
     8041 gttaaagatt ttcatgcctg aagctggcga agagttcact ttaccgcctt tgaaagttat
     8101 gctgttgtta gttcatggag ccttgcagca gtatgaacat gggtattcct ttgaagatgt
     8161 ctacgaccta tacgatgaat acgtggacaa tgggggagac caaacaactt tcatgacaga
     8221 ggttttaatg ccactatttg aagtatcggg ttttactcca cgaggaagca agaacaagaa
     8281 aacttccaag aagaaaatga cagtagtcga gtaatcttaa cagtaacgca gattattgag
     8341 aggctttatc ctatgttttt ggacattgga ggcaagcctc ttgatttttg ggatttgacg
     8401 gtgcttgaaa tcagagaaat gattgaaagc tacaaccgtg tcaaaaccca agagcgtaaa
     8461 gagaagatta ttgactcata cagactttcg cagatgattt ccaatcacgt ttctttatta
     8521 ctgtccaatg acgctaagat tgttgagttc tgggagtatg cgcctgagtt atttgtagaa
     8581 gaacaacaag cggtagaact ggaacgacag aaacaagcac ttttgttgca taaggaacgg
     8641 atgcgtgaat ttgcagagag acataatcga aaaaggaagg aggaagtaaa tggcaactct
     8701 tgatgaattg aaagtcatga ttgacgctga gatagcgcct ttcaggaaga agatgaaaga
     8761 agtcgagaat caggtcaaag gaacatctga ccaagtgaag aatgccactg ccaaagttcg
     8821 tgaacagtcg aactctatcg gtagtgcgtt tggtaagcta gctaagttcg ctggttttgc
     8881 aatccttggt aagaaattac ttgatgttgg gatgtattca acgcagactg ctcttgaagt
     8941 gtcagcggct atgaaccaaa tcaagcgcca gatgggcgag agttcgcaat ctttcttaaa
     9001 atgggttaac gataacgcca acgctatgaa catgggtgtg ggtgaggcta ctaactacgg
     9061 tgcggtctac tcaaacttat tttctgggtt tatcaaagat accaacaagc taagcgccta
     9121 taccgctaag atgttgcaga catcggcagt ggttgctgaa ggttcagggc gcacgattac
     9181 agacgttatg gagcggattc gctcaggttt gctagggaac accgaagcaa ttgaggacct
     9241 aggaatcaac gtcaatgtgg ctatgattga gtctactgaa gcctttaaga agttcgcaaa
     9301 cggacagagc tggcaacagt tggattacca aacccagcaa caaatccgcc ttatggctat
     9361 tctggaacag gctacagcca agtatgggaa taccttgtct aattctgtaa atggtcgtat
     9421 cagcctattt aagtcgctga tgaaggacgc agcattgaac cttggtaact ctatgttacc
     9481 gattatcaat gccattatgc ctgtcttgaa ctcttttgcg atggtcttga agaacgttac
     9541 tgctaaactc gctgagttta tcgctttgat gttcaacaag aaagcaacag tgaaagatgg
     9601 tgttggtgga gcagttggag acatgggtaa cgccatgaaa gacgctgcag gcggagcagg
     9661 agaccttgct gatgcagtag acgacgctgg agattcagca ggaggacttg ctgacaatct
     9721 tggagactcc gccaaaaacg ctaagaaagc tgctaaagag ttgctaggtc ttttgggatt
     9781 tgatgagatt aacatcttgc aaaaaccaaa agatgacgac gcaggcggtt ctggaggcgg
     9841 tggcaaaggt ggtaaaggaa agggaggcgg tggcggacct ttcaaagaca tcttgccaga
     9901 agtcgagttg accgacatgg acaacaaatt caagagcatt tttgatggtc ttggagataa
     9961 gctcaaaggg ttgtttgacc tcttcaagaa aggttttgat gcagcattta gaccagaagg
    10021 tataaaacgc attaagactg ccttagacca aatagctaag acaatgggag aaatcgtcac
    10081 tgacccaagg gttgtgaatg cctttaaccg aatggctgag aaaattgctt atgctttagg
    10141 gcaagtgaca ggctcaataa ccactatcgg gctaggtatc ggtgttttcc ttgccgaaag
    10201 tattgcaaat ggccttggaa ggcaaaaaga acgcattatc agggcgctag tcgctttgtt
    10261 tgataatgtt ggtaaccttt ccgaggcagt aggaaacata gctcaggact tttctagtgc
    10321 tttctacgac gtcattacct caactggtgc ggttcgtatc ggtagcgcta ttgtgtcaac
    10381 tctgttgagt ttgacatcta ccattgttga agttggtagt aaattagcag gaagtttgtt
    10441 taaaggtttt gaaaaagtcg ttgtgacaag cgctcctaaa atttcatcag tcttccaaag
    10501 tttattagat actgttgcgc ctgtatttga gagcattgaa aggtctgtta acaaatttgg
    10561 cgatggctta agtcgtgttt atgatgaaca tgtagtccct gctattaact ctattgctaa
    10621 tgcttttaat gggctaattg acattattca gattctctgg gagaattcct ggcaaccttt
    10681 tgctgagttt ttatcaggag tattcggtgt tagtattgaa ggaatttcag atttattagg
    10741 aggtggcctt ttagccactt tgggactatt ggcggatgct attaagttag tggcagatgg
    10801 tttcaccgtt ttttctgact ggtgtaaaga aaacaaagaa cctatcgtag ctttgataac
    10861 aacttggcaa acgattaatt tcttatcatg ggcagaacaa gctggaggcc ttgcaggagc
    10921 attcagcttg ttaggtag
//
LOCUS       DAVDHC010000052        10867 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVDHC010000052 DAVDHC010000000
VERSION     DAVDHC010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.052"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..255
                     /locus_tag="VUR43_002072"
     CDS             <1..255
                     /locus_tag="VUR43_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5413697.1"
                     /translation="SGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHALSKERSKVE
                     NIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            323..571
                     /locus_tag="VUR43_002073"
     CDS             323..571
                     /locus_tag="VUR43_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413698.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            702..1874
                     /locus_tag="VUR43_002074"
     CDS             702..1874
                     /locus_tag="VUR43_002074"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET5413699.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1874..3148
                     /locus_tag="VUR43_002075"
     CDS             1874..3148
                     /locus_tag="VUR43_002075"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET5413700.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3183..4148)
                     /locus_tag="VUR43_002076"
     CDS             complement(3183..4148)
                     /locus_tag="VUR43_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET5413701.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4129..5583)
                     /locus_tag="VUR43_002077"
     CDS             complement(4129..5583)
                     /locus_tag="VUR43_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET5413702.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5636..5833
                     /locus_tag="VUR43_002078"
     CDS             5636..5833
                     /locus_tag="VUR43_002078"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413703.1"
                     /translation="MQAFYVKKEEKLSNDYHKINTGNQSNFYENVKDNEIKDFLIKVS
                     NLFFKESLMKQSKTINLKLAR"
     gene            5960..7843
                     /locus_tag="VUR43_002079"
     CDS             5960..7843
                     /locus_tag="VUR43_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET5413704.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGFDDTTMVIVTNTADYASVAPVATGSVAKGNAVIE
                     VKI"
     gene            7992..8879
                     /locus_tag="VUR43_002080"
     CDS             7992..8879
                     /locus_tag="VUR43_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET5413705.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(9199..9816)
                     /locus_tag="VUR43_002081"
     CDS             complement(9199..9816)
                     /locus_tag="VUR43_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET5413706.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10231..10419)
                     /locus_tag="VUR43_002082"
                     /pseudo
     CDS             complement(10231..10419)
                     /locus_tag="VUR43_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT         3167 a         2136 c         2400 g         3164 t
ORIGIN      
        1 agtggttatc aagggctcat gaagatatat cctcaagcac aaactccacg taaatccagc
       61 aaactcaagc cgctaacagt tgaagataag gcttataacc atgcgctatc taaggagaga
      121 agcaaggttg agaacatctt tgccaaagta aaaacgttta aaatgttttc aacaacctat
      181 cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctggcat tatcaatcat
      241 gaactaggat tctagttttg caggaagtct actactttcc ttattgtctg taaatctact
      301 gaccttgttg tttatcccag tcatggtttc tagttcgggc tcagagtttc aaagtggatg
      361 gcaagagcat caattgattg ctgagaaggt tagtaaaaca cttgataaga catttgataa
      421 ggatgtcaga gaaattccga ccagtcagtt ttatcaaaaa tttgtagatg agatgggaag
      481 gacttactca ggaaatttga tcctccagga gctgataact gtgaatggag cttataaagc
      541 tacttatatc ggtgaactct ctagcaacta atcattcttt aaaatgatga ccaataagag
      601 gcttgatttg gtgaatcaag tcttttttct ctcttttact gccatttgtg ataaaatagt
      661 atagaacgat tttttacatg aatgataaaa cagaggtaaa tatgacaatc ggtattgata
      721 agattggttt tgcgaccagt caatatgtct tgaaattaca agacttagca gaagcgaggg
      781 gaattgaccc tgaaaaatta agtaaaggac tcttactcaa ggaattgagt attgcgcccc
      841 taactgagga cattgtgacc ttggcggcca gtgctagtga ctctatttta actgagcaag
      901 aaagacaaga agttgacatg gtcattgtgg ctaccgagtc aggaattgac cagagtaagg
      961 ctgcggccgt ctttgtgcat ggcttgctgg gcatccagcc ctttgctcgt agtttcgaga
     1021 ttaaagaagc ctgttatgga gcgactgctg cccttcatta tgccaaattg catgtggaaa
     1081 attctccgga gtccaaggtc ttggtcattg ccagtgatat tgccaaatac ggtattgaaa
     1141 ctccaggaga accaactcaa ggtgctggaa gtgtagctat gttgattaca caaaatccac
     1201 gcatgatggc ctttaataat gacaatgtag ctcagacccg tgacatcatg gatttctggc
     1261 gaccaaatta ctcgacaact ccttatgtaa atggtgttta ttctacccaa caatacttgg
     1321 atagtttgaa aacgacttgg cttgaatatc aaaaacgcta ccagcttact ctggatgatt
     1381 ttgcggctgt ttgtttccac ttgccttatc ctaaattagc gctaaaaggc ttgaaaaaaa
     1441 tcatggataa gagcctgcct caagagaaaa aagacctctt acaaaagcat tttgaccagt
     1501 ctattctcta cagtcaaaag gtggggaata tctacacagg ttcacttttc cttggacttt
     1561 tgtctctctt ggaaaataca gatagcttga aagctgggga taaaatcgcc ctttatagtt
     1621 acggaagtgg agctgtggct gagttcttca gtggtgaatt ggttgaagga tatgaagctt
     1681 atttggataa agaccgtttg aacaagctca accaacgaac tgccctatcc gttgcagact
     1741 atgaaaaggt cttttttgag gaagtaaact tggatgaaac aaactctgcc cagtttgctg
     1801 gctatgaaaa tcaagatttt gccttggttg aaattcttga ccaccaacgc cgttatagca
     1861 aggttgaaaa ataatgaaga taagttggaa tggattttct aaaaaatcat accaagagcg
     1921 cctcgagctg ctaaaagctc aggcgctcct tagtcctgag agacaagcta gtctggagaa
     1981 ggatgaacag atgagtgtga ctgtggcaga ccagctgagt gagaatgtgg tgggaacttt
     2041 ttctctgcct tattcgctgg ttccggaggt acttgtcaac ggtcaggaat acaccgttcc
     2101 ctatgtgaca gaagaaccct ctgtggttgc ggcggccagc tatgccagca aaatcatcaa
     2161 gcgtgcaggt ggttttactg cacaagtcca tcagcgccag atgattgggc aggtagccct
     2221 ttatcaagtt gctaatccta aactagcgca agagaagatt gccagcaaga aagcggagct
     2281 cttggagctt gccaatcaag cctatccttc tatcgttaaa cgtgggggtg gggcgagtga
     2341 cctgcatgtc gagcagataa aaggtgaacc agactttctc gttgtttata ttcatgttga
     2401 tacccaggaa gccatgggtg ccaatatgct caacaccatg ctggaagcct tgaaaccagt
     2461 cttagaagaa ctcagtcagg gacagagtct catgggaatc ctgtccaact acgcgaccga
     2521 ttctctggtg actgcaagct gtcgcatggc ctttcgctac ttgagccgcc aaaaggatca
     2581 aggacgagag attgcggaga aaattgcatt ggctagtcag tttgcgcagg ctgatcctta
     2641 ccgagctgct actcataata aaggaatttt taatggtatt gatgcgattt tgattgccac
     2701 tggtaatgac tggcgtgcca tcgaagctgg ggcccatgcc tttgccagtc gagatggacg
     2761 ctatcaaggt cttagctgct ggacgctgga ccttgaaaga gaagaattgg tcggtgagat
     2821 gaccctgccc atgcctgtag cgactaaggg tggctctatc ggcctcaacc cacgtgtagc
     2881 tctcagtcat gatctactag gaaatccttc tgccagagaa ttagcccaga ttatcgtgtc
     2941 catcggtctt gctcaaaatt ttgcagccct caaagccttg gtaagtacgg gcatccagca
     3001 aggccacatg aaactacagg ccaaatccct agctctccta gctggggcta gtgaatctga
     3061 agttgctccc ctagtagagc gcctcatctc agataaaacc tttaacctag agacagccca
     3121 gcgctatctc gaaaatttaa gatcataaaa actcagacga atcggtctga gttttcttgt
     3181 gtttaaatac tttttcctgg taatagcgta actggtaaga agtaaccagt tgtggcgact
     3241 tccttgcctt caatcttttg caagagaaga tcaatagtga gacaagcaat ctcttccaaa
     3301 ggttgcttga tagtagccaa ttgagggtag taattttcga taaagtaggt cccatcatag
     3361 ccgatgacct tgagctcttt tgggacagaa atgcccaatt cttgagcgat tttaatgacc
     3421 agaatagctg tcaaatcatc cgaagcaaaa atggcatctg gtttttcccg ggtcaagata
     3481 ttcttgattt ccatttcttt tctgacggga gaaaagtcac tggaaacatt gataatagga
     3541 gcttttggga gtacggatgc aaaaccagcg tggcgcagtc cggttggcga attggaattg
     3601 tcattccctg taatcatgat gatagactgg gcacctgtct tgaccaaggt ttgggcagca
     3661 agaaccccac cagcatagtt gtcagaggag acaacaggga tgtctggcga taggtttcgg
     3721 tcaaaggaaa taatcggcgc tgtcacacga ttgtagtctt cgattcctag gttgtgacta
     3781 ccagaaatga tgccgtccac ctgattggct tccaacattt cgatgtattc acgttccttc
     3841 tcagaatcat gttcactgtt gcagatgatg gtcttgtaac catttttgaa gagttggtgt
     3901 tccaatttat caatcaattc tgcatagaaa acattggaaa tattggggaa aatcaagccg
     3961 attaacttag ctgattttcc ttgcagacta cgagccaggt tgttgggttt atagcccaat
     4021 tctcgcatgg cttcattgac tttttggatg gttttctcag atagataccc ttttttattg
     4081 ataacccgag aaacggtagt aggactgacg cctgcaagtt tggcgacatc agttagtttt
     4141 gcgaccataa tctaattcat agtaagttcc agttgggttt ccagatttga tcaggatacc
     4201 attttggtcc gcatgtggga agacacgacc agaaaatact ttttctcctt tattgatgaa
     4261 aatttcaaag acagagttat cgatgaagat tgtagcagta gtagcctgat tctcgatagg
     4321 gcaagagcga gttgtcccaa attcttgggc atactgttct ccagcctggc tacgatccac
     4381 tgtcacttga ccgtttacaa ggtcaaagtt gattgaaagt cccttacctt ctttatcagc
     4441 aagtaagaca atctcgctct ggctattagc ttccaagttg agttcaagtt cgtaagtgtt
     4501 cttggtttgg gaacggtttg agaaggcttc ttcagaagca cgaaggtcct taatagcagc
     4561 gactggatac tggtagagct tgtcgtcttt gatagtgagt tccttgacca aagagaaggt
     4621 tccttggtgg tcaaaacggt cagatgggta agaaacatct ggcaaaccaa gccagctaac
     4681 tgctagagca cgcccatcag gagcgttgaa ggcttgagtt gcataggctt cgaaaccgta
     4741 atccatgttt tgaagttgag acacatctac cattttggca tttttagggt caaaggaagc
     4801 cccaatctta tacatatttg gaaagatatt atcgtagtct agaactttct tatccaatcc
     4861 ttgtggacag tagagaagga caggctgttc ctctacaaag accagattag gacattccat
     4921 catgtaggca gtacggtcgt tagcaaagtc aaggtcgcca actgcttgcc agtttgtgta
     4981 gtcgttattg acagccttgt agagacggac gaagcctttt ttctccaagt cctgtccacc
     5041 gacgacagca tagtattgac ctttaaagtt aaaaatttgt ggatcgcgga agtggtcagt
     5101 agagtctgct ggctggtcaa tcaagatctt gtcaatcttt gtaatcttac cctccttgtc
     5161 catcaaagca ccgatttggt atgggtgacg gatccagttt tcatcgcgaa catttcctgt
     5221 ataaaatagg aataagttat cgccaaattg catggcagaa ccagagtagg caccgtggct
     5281 atctaatgga gtatccggca aaactttgat tccagtttct ttaaagtgaa ccaaatcatc
     5341 actttctagc tgtgcccaag atttcaaacc gtgggctgca ccaaaaggaa aattctggta
     5401 aaagaggatc cacttgccat caaagtaaga aaagccattt gggtcgttga gaagtcctgt
     5461 ttttggctca acatggtaat gagtatgcca tggagattgt gccatatttt cctttatatg
     5521 ttgaatttct tcttgcgtcc aatcttgata aagtctgtaa cgacgctcag ttgtccattc
     5581 cattcattcc tccaaaaatc ttatcacttt taatagtaac tgttttcgat aaaaaatgca
     5641 agccttttat gttaaaaaag aggaaaaact atcaaacgat tatcataaaa taaatacagg
     5701 aaatcaatca aatttttacg aaaatgtgaa agataatgaa ataaaagact ttttaatcaa
     5761 ggtttcaaac ttatttttca aggaatccct gatgaaacag tcaaaaacaa tcaatctaaa
     5821 gcttgcccgc taagtggata gaatattttt tctgcaaaac gcttgacata tttttaaaac
     5881 atgataaaat aatagtcgta agggcgaata aaatcgcttt caaacaagaa caaaatgtta
     5941 tataaggaga tttttgcaaa tgaacaatca ggaaattgca aaaaaagtca tcgatgcctt
     6001 gggcggacgt gaaaatgtca atagtgttgc ccactgtgcg actcgtctac gtgtcatggt
     6061 caaagatgaa gagaaaatca ataaagaagt gattgagaac ttggaaaaag ttcaaggtgc
     6121 tttctttaac tcagggcaat accaaattat ctttggtaca ggtacagtta acaaaatgta
     6181 cgatgaagtt gttgtacttg gcttaccaac atcatctaag gatgacatga aagcagaagt
     6241 tgctaaacaa gggaactggt tccaacgtgc tatccgtact ttcggtgatg ttttcgttcc
     6301 aatcatccca gttatcgtag cgacaggtct cttcatgggt gtgcgtggtc ttttcaacgc
     6361 tcttgaaatg ccacttccag gtgactttgc aacttacaca caaatcttga cagatacagc
     6421 cttcatcatc ttgccaggtt tggttgtgtg gtcaaccttc cgtgtatttg gtggaaatcc
     6481 tgccgttggt atcgttcttg gtatgatgct tgtctctggc tcacttccaa acgcttgggc
     6541 agttgctcaa ggtggtgaag taacagcgat gaacttcttt ggtttcatcc ctgttgttgg
     6601 tttgcaaggt tccgttcttc cagccttcat catcggggtt gtcggagcta aatttgaaaa
     6661 agctgtccgc aaggttgttc cagatgtcat tgacctcttg gtaacaccat tcgtgacact
     6721 tttggtcatg tctatccttg gactctttgt cattggacca gttttccacg ttgttgaaaa
     6781 ctacatcctt attgctacaa aagcgattct tagcatgcca tttggtcttg gtggtttctt
     6841 gattggtggg gttcaccaat tgatcgtcgt gtcaggtgtg caccacatct tcaacttgct
     6901 tgaagtgcaa ttacttgctg ctgaccatgc taacccattc aacgctatca tcacagctgc
     6961 tatgacagct caaggtgctg ctactgttgc ggttggtgtt aaaacaaaaa atccaaaact
     7021 gaaaacactt gctttcccgg ctgctctttc tgccttccta ggtattacag agcctgctat
     7081 cttcggggtg aacttgcgct tccgtaaacc attcttcctt tcattgattg ctggtgcaat
     7141 cggtggtgga ttggcttcta tccttggact tgctggtact ggtaatggta tcaccatcat
     7201 ccctggtaca atgctttatg ttggtaacgg acaacttcca caataccttc ttatggtagc
     7261 tgtatcattt gcccttggtt ttgctcttac ttacatgttt ggttacgaag atgaagtaga
     7321 cgcaactgca gctgcaaaac aagctgaagt ggctgaagaa aaagaagaag ttgcgccagc
     7381 agctcttcaa aatgaaacac ttgtaactcc tatcgttggt gatgttgtcg ctcttgctga
     7441 tgtcaatgac ccagtcttct caagtggagc tatgggacaa ggtatcgctg tgaaaccaag
     7501 ccaaggcgtg gtctatgcac cagctgatgc tgaagtttca attgcctttc caacagggca
     7561 cgcttttggt ttgaaaacaa gaaatggtgc tgaagttttg attcacgttg gtattgacac
     7621 tgtatctatg aacggtgacg gttttgaagc aaaagttgct caaggtaata aggtgaaagc
     7681 tggcgatgtt cttggaacat ttgactcaaa caaaatcgct gcagctggat ttgatgatac
     7741 aacaatggtt atcgttacaa atacagctga ctacgcttca gtagctccag tcgcaacagg
     7801 ttcagttgcg aaggggaatg ctgtgatcga agtgaaaatc taatcaatcc tctctaatgt
     7861 gaaaacgaac aaatgacatg tttgttcgtt tttattagat agtaagattt acagaggaaa
     7921 atctaaaaaa tagagacatt tagactttcg aagtatgcta taataaagaa aataaaaaca
     7981 agaggtttat catgacaaaa ttatatggaa gcttggaagc gggcggtaca aagtttgtct
     8041 gtgctgtcgg tgatgaaaac tttaacgttg tagaaaaaac acaatttcca acaacaactc
     8101 caatcgaaac aatcgataaa accattgagt tcttctcaaa attcgataac cttgctggtc
     8161 ttgcagttgg ttcatttggg ccgattgata ttgacaaaaa ctcaaaaact tatggcttta
     8221 tcacgacgac tccaaaacca aactgggcaa atgtggactt gcttggtgcc cttcgtcgcg
     8281 ccctaaacgt gccaatgtac ttcacaacag acgtaaacag ctctgcttac ggtgaaatgg
     8341 ttgcccgtaa caatgctggt ggtcgtatcg aaaacttggt ttactacaca atcggtacag
     8401 gtatcggtgc aggcgtcatc caacgtggtg agtttatcgg tggtgtgggt caccctgaaa
     8461 tgggtcatta ttatgttgct agacacccaa tggatattga aaaagagttt aagggtgttt
     8521 gtcctttcca taagggatgt ctagaaggtt atgcagctgg tccaagtttg gaagctcgta
     8581 caggtgtacg tggggaaact attgaactca acaaccctgt ttgggatgtt caagcctact
     8641 atatcgctca agctgcggtt aatgcgacag tgactttccg cccagacgtg attgtctttg
     8701 gtggaggggt catggctcaa caacatatgc tggaccgtgt ccgtgagaaa tttacatctc
     8761 ttcttaatgg ttacctacca gtaccagatg tgcgtgacta tatcgtgacg ccagcagtcg
     8821 caggaaatgg ttctgccaca cttgggaact ttgttcttgc aaaagaagtt tcaaaataaa
     8881 gcacaaaatc cgcttgggaa accaaacgga ttttgtggtt gaaaacaata tttttgagcc
     8941 tttccttaag tgattacgga cggtagcgac tttcttcgaa attccatacc taaactttga
     9001 gcctagtgtc tcaaagtttc cgaatacctg aaaccattag atttcaggtg tttctatcac
     9061 ggcggaaagg ctaggtaagt cctcgcctca ctatcgaaaa atatgcatga tttccatacc
     9121 aaagtatatt tagtatcaag ctatagttaa tctacgcttt aaaaatccac ttgggaaacc
     9181 aaacggattt tttacgtgtc aaagcatttg ccagaaaaag tcaataatat aggtcagacc
     9241 gtaggtataa accacgaggg taaagggttt ggtcagaatg atgatggtca tgtagcgctt
     9301 gaaactcatc ttggtcaggg cagccagcat acagagaaag tcagctgggc taatgggcca
     9361 aatcatcata aaaataaaga agcggtcaaa acgattgccc ttatctagcc agccgatgta
     9421 cttgtcgtag gtgcgcttgc tgacgacaga ctggacaaag gcagctccgt ataggcgcac
     9481 tagataaaag ataatggcac agccaatcac gatgccgata tagttgtaga tagtcccgat
     9541 gatgtgcccg tagataaaga ccccagccac cgaggtcaag gcccctggaa tgatagggac
     9601 gacagtctgt aaaatctgta aaaagataaa gagaggtgga ccccagatgc ctgcctgctg
     9661 gataaaggca gagagggttt ccttggattg taaaatccca gcctgataag cccaaataca
     9721 gaaaatcaaa ctcccaaccc caccgacaat cgatgagata ttgataactc gctgcagaag
     9781 gggagaaaca gctttcattt gtttatcctg tgacatgtaa actcctcata gatagtatat
     9841 ttctactata ccatattttg gaggagaaag ggggaatgag tcttttttga taaggaatag
     9901 aaagtaaata gcccttcgag acttagaata ggtctgtcaa ctaaaggtta tatgcattct
     9961 aggtttcgaa taatcgcaat tccataaatt taaaagcatt ctaagtttcg aatagcttat
    10021 ctgagataat tttgaggcat tcgcgctttc gaatagtcat ttttcctaaa gtttagatgt
    10081 attctgaagc tagaaagact aaaatctaaa agtagtaaga gtctctctct gatggacgta
    10141 atttatggct agtatgaatc ctttgaattg ttagttaatt ttaatattaa tcagttctga
    10201 aataattact aaatatagtt agatggtgaa ttaattattg ctaaatttca agttcaagtt
    10261 agtcatccag aagtcttctc tgggggactt gtagttcaag cattttttag gatagttgtt
    10321 aatccacttt tcgatgaatg cgacttcctt tgtagtcgtt ttcttagttc cctgaggtaa
    10381 ccatctatga atgagtctgt tgtgattttc attagatcct atagtgatgt gcataataga
    10441 tatagcagat tgaaactaga atagtataca tctacttcta aaacattgtt agaaatcaat
    10501 ttgactgtcc tgatcaattt gtcctgtttt tatttcattt tactatataa tccttagaaa
    10561 acatatggga caagcggttg aattctgttc cgtccattag tagataaagg attactcctt
    10621 cttgaaatga cagatgaact tgtttcttat aaaaatgttg tctgaaacta ttcgcctttt
    10681 tccagaagtt ttagaggaag aaaactttat gaggaaaaag gagttactca aataacaatt
    10741 caggattaaa aatagacagt tgaggagcgg aaggtataaa ttaagtttgc tactgtataa
    10801 tggatttatc actaatactc ttcgaaaatc tcttcaaacc acgtcagctt cgccttgccg
    10861 tacgtat
//
LOCUS       DAVDHC010000053        10715 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVDHC010000053 DAVDHC010000000
VERSION     DAVDHC010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10715
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.053"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(70..930)
                     /locus_tag="VUR43_002083"
                     /pseudo
     CDS             complement(70..930)
                     /locus_tag="VUR43_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
     gene            complement(1206..2192)
                     /locus_tag="VUR43_002084"
     CDS             complement(1206..2192)
                     /locus_tag="VUR43_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET5413707.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(2464..3939)
                     /locus_tag="VUR43_002085"
     CDS             complement(2464..3939)
                     /locus_tag="VUR43_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET5413708.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(4197..5120)
                     /locus_tag="VUR43_002086"
     CDS             complement(4197..5120)
                     /locus_tag="VUR43_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET5413709.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(5134..6063)
                     /locus_tag="VUR43_002087"
     CDS             complement(5134..6063)
                     /locus_tag="VUR43_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET5413710.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLFARRVDPNSALF"
     gene            complement(6382..6732)
                     /locus_tag="VUR43_002088"
     CDS             complement(6382..6732)
                     /locus_tag="VUR43_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413711.1"
                     /translation="MTGVSNPTTDSAPLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTAAELI
                     DNLKEVIAKLKANA"
     gene            complement(7158..7313)
                     /locus_tag="VUR43_002089"
                     /pseudo
     CDS             complement(7158..7313)
                     /locus_tag="VUR43_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(7499..8110)
                     /gene="rpsD"
                     /locus_tag="VUR43_002090"
     CDS             complement(7499..8110)
                     /gene="rpsD"
                     /locus_tag="VUR43_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET5413712.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(8305..9357)
                     /locus_tag="VUR43_002091"
     CDS             complement(8305..9357)
                     /locus_tag="VUR43_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET5413713.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(9354..10052)
                     /locus_tag="VUR43_002092"
     CDS             complement(9354..10052)
                     /locus_tag="VUR43_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET5413714.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(10219..>10715)
                     /locus_tag="VUR43_002093"
     CDS             complement(10219..>10715)
                     /locus_tag="VUR43_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET5413715.1"
                     /translation="ALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDN
                     IVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSSTN
                     TMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLKNK
                     KEEN"
BASE COUNT         3113 a         2226 c         2069 g         3307 t
ORIGIN      
        1 ttcaatcctg tcatccttgg caggattttt tctatgtcaa aaaagcaagt cgattgacct
       61 gcttctgctt tacttttctt gtgctaatgt tttaaaatct tgtcctagga tgggttgtat
      121 ttctatttga ttggcgtcta gctggtggta aaaagatggg ggtaatacct ctaagaattt
      181 tgcatagtcc aagcgagcta tggattcata gtcttctggt ttagagccgt ctcctgtgat
      241 ttgaaccaag tcaatctccc actggacttc cttatccacc aattgctcaa tataggctgc
      301 aggaacaaac ggttctctcg gtaaaactgt cttgactcct taagctagat ggtaaacgcc
      361 atgcactttt ccttctccat cctgatagaa ggaaactctc gcaaagtagg catctgtctc
      421 ttgaaccgca cgcacacgcg cttcaaactg agccaagcca tctgcctcta aaaagctttt
      481 caagttctca cgactaaaga aaataggatt aaaaattcct tggcaaatcg taaaacgagc
      541 tacagagtct gctagatagg cttgaatact tgcttggaaa taagcttcaa aatcaaaacc
      601 atctagccct tcaatatcag tccctgtata agcaagcaaa gcatctaaaa atgacttgat
      661 aatccgccag tctgtctctg ttagtaggtc aggaagatcg acacggtaag ccttttgacc
      721 atcagcataa ctgaccttaa aaagaaattg tgattgcccc actatcgcac actcaatata
      781 ctcgagacga ttaagaggct gacggagata gactacatca tagctatgtg actccaaacc
      841 gtctagcaag gccaagatcg acttggcagt caaaatctct tgttctccta aaatgctctg
      901 tttatttgga ataaaaaatg ttttcgccat aactggactc ctttgaaatc gtttacatac
      961 agtatacctt attttttctg aaagatacaa aaacaaactt tatattcttc gaaaatctct
     1021 tcaaaccgcg tcagcttcgc cttgccgtag atatatgtaa ctgacttcgt cagtcttatc
     1081 tacaacctca aagcagtgct ttgagcagcc tgcagctagc ttcctagttt gctctttgat
     1141 tttcattgag tattagattt ttgagtacaa agcatagaaa aacagcccct aaggactgtt
     1201 tgatcttata cagtagctgc ctgatccaag ctttcaccga tagcggctag gcgctcgatc
     1261 acttcagctt gtgtcaattc attttttgaa acatagcggt tacgtgggtg aacacggcac
     1321 tcgtgtgagc atccacgaag gtacttgtct tcattttctt ctgatgtcaa gatacgacgg
     1381 ttacagaagg gatttccaca gttgacataa cgttcacatg gtgttccatc aaaccagtct
     1441 ttccctacga tggttgggtt gacatggttg acatcaacgg cgatacgctc gtcaaatacg
     1501 tacatttttc catcccaaag ctcaccttga acttctgggt ctttaccgta agttgcgatt
     1561 cctccgtgca attggccgac atctttgtag ccttcacgga ccatccagcc tgagaatttc
     1621 tcacagcgaa cgccacctgt acagtaaacc acgacacgct tgtccatgaa tttttccttg
     1681 ttatcacgga cccattgtgg taactcacgg aagttgcgaa tatctggtcg aatagctcca
     1741 cggaaatgtc ctaggtcgta ctcataatcg ttacgtgtgt caaggacaac ggtatcttta
     1801 tcaagaagtg cttctttgaa ctcttttgga gacaagtaag cacctgttgt ttcaagtggg
     1861 ttgatgtcat tgtcaaagtc gttgtcttcc aaaccaaggt ggacaatttc tttcttgtag
     1921 cgaacaaaca tcttcttgaa ggcttgttca ttttcttcgt caatcttgaa ccaaagttct
     1981 tccattcctg gaaggctgtg aacgtagtcc atgtattttt gagttgtttc atagtcacct
     2041 gaaactgttc cgttaattcc ctcgtcagcg actaggatac ggcctttaag gccgattgat
     2101 ttacagaaag ccaagtggtc tgcagcaaat tgctctgcat tttcaattgg agtataaagg
     2161 tagtaaagta agacacgaat atcttttgcc ataagatttg ttctcttttc tattcttaaa
     2221 ttttctaaat tttttattta tccatactag tatacctgct tgagaaaacg aatgcaattt
     2281 atttgactgg aaattgtaga gggttctcga aatttcctga atggttaaaa taaggacaag
     2341 agaaaacatg gatatctata tccttgtgcc aaaaaaacca ctgccctccc cagaccaacc
     2401 tgaggaaagc agtgattctt attttaggag ttaggaatga atacacgaaa tcaatttagc
     2461 tgattatttt ttgtttttca agaattcatc gtattgtttt tgcatttcgt tcaatacttt
     2521 ttcgtaggca ccttcagatt tcaatttttc catcaattct ggaatcgctt tatctgggtc
     2581 tacagtacca gtgttgatag ctgtatcaaa ttgttgcatt gtgttagcaa tagctgagat
     2641 ttcagatttc acattgtcag tattgaagat aaatccaagc gctggagatt ctttagcttc
     2701 tgccaattct ttcttagaat tttcgatttg ttggtctgta acgttttcgt tgatgtaaag
     2761 gatccagttg ttaccagtgt tccatccacc catgtgagtg tttcctttgt agccatcaag
     2821 aacgcgaaca cggttttctt taccttcaat tttttcccag ttcttgcctt ctggaccgta
     2881 aacaagaccg ttcaagagtt ctgggttcgt attcaagagg ttcaagattt ccattgattt
     2941 ttctttgttc ttagagttgt ttgagatgac aaagttagca acttgtgttg tttggttttt
     3001 cttgatgaag ttagtaattg gtttgatttg gatatctttg ttggcaacac gtgaaagcaa
     3061 gctgttaccg tagtcagctg gtcctactgt ttcttcacga acgaaccaag tatcttgttg
     3121 aaggtcaaag gaagtatcgc ttgttgcgac gtcttttgga atgtagccag cttcatagaa
     3181 tttgtgaaga gtcttcaagt gttctttgaa acgaggtact tcgtaacggt ttacaacttt
     3241 agtagtatcg ccttcaaggt caataacgaa tggaagaccg tttgctactg ggtagtcaaa
     3301 gttatcagat gggatgaaaa ctttaccaat agcaaatggt actacgtctg gagctttttc
     3361 tttgatttgt ttcaagactg gctcaagagt ttcgtaagaa gtaacacctg aaatatcgat
     3421 accatatttg gcaaggagag ttccgttgaa ggcaaagttt tgagatgatg ctacgttggc
     3481 tgcaactggt acagcgtaaa tcttaccatt tacagtatta cccttgatat aagctggatc
     3541 aagtgccttg taaaggtctt taccttcttt tttgtacaat tctgtcaagt cagcataagc
     3601 acctttttga gcatttacaa tatagttatc tgcaaaggcg atatcatagt tttcaccaga
     3661 tgatgtgata actgacattt tcttaccata gtcaccccag ccaaggtatt ggatatccaa
     3721 tttagcacca actttttctt cgatgatttt gttggcattt gctaacaatt catccaagtt
     3781 atctggtttg tcaccgattt ggtacatttt gataacaggt ttgtcacctg aatcagcagc
     3841 ttttttgctg ttacctgtca aatttccaca agcagcaaga cctgcagcca aagcgactac
     3901 actagcagat gcaaaagcat attttttcca gtttttcatg ataaaaactc ctttttttat
     3961 ttttaaactt ataaacaatg taatgatctt atactcaatg aaaatcaaag agcaaactag
     4021 aaaactagcc gcaggctgct caaagcactg ctttgaggtt gtagataaga ctgacgaagt
     4081 cagttacata tatctacggc aaggcgacgt tgacgcggtt tgaatttgat tttcgaagag
     4141 tattaacttc acacaaggga agttgggaac tgagaaatgt tctttttcaa taagcactat
     4201 tctttcacac caccgatagt caaacctttt acaaagtagc gttggaagaa tggatataaa
     4261 atcgcgattg gaagggttgc aaccacaacc atggccatac gacctgtttc tttcggtaga
     4321 gcaactccca gttgaccagt caagccgacc gctttggcaa tgtagtccat attttgttga
     4381 atttgcatga gcaaatattg caatggatac aagttgtcac tcttgatgta aagaagggcg
     4441 ttgaaccagt cattccagaa accaagagct gtcaaaagcg tgatggttgc gatacctggt
     4501 agtgacaatg gcaaacagat ttggaagaaa atccgggcct cactggcacc atcgatacga
     4561 gccgattcga gaatggcttc tggaatggtc ttcttgaaga aggaacgcat caagatgata
     4621 ttgaatggtg agagaagcat tggaacaatc aaggcccaaa cagtgtcacc aagctgaagt
     4681 acacgggtca ccatgatata acctggtacc aaaccagcgt tgaacaacat actgagaagg
     4741 acgaagatgg taaaaaatct gcgatactta aaggttgtcc gtgaaatagc gtaggcatag
     4801 gttgttgtga taaagacatt tgtcaatgtc ccaactacgg ttacaaagac agagatgaag
     4861 agggcttgta ggattttatc cttaaactgt gccaaaaact caaaaccgtc taagccaaat
     4921 tgggatggga agaagctata gccgtattgg aggaggcttt tctcgtctgt cactgaaata
     4981 atgataacga atacaaaagg taggatacaa gagagggcaa tcaaacccga aatgatactg
     5041 aagaagatat ctgctttctt actgaaggag tgaatgccga cattatcaat tttttctttt
     5101 ttaattttct tttttgccat attctcctcc tttctagaac aaagctgagt ttggatcgac
     5161 tcgtcttgca aacaagtttg ataggataac cagaatcaaa ccaacaacgg attggtaaag
     5221 accggctgct gcagccatac cgatatctgc tgtctgagtc aaaccattaa aaacatatac
     5281 gtccaaaacg ttggttacat tgtaaagctg accagcattg tgtgggattt gatagaagag
     5341 accgaagtct gcgcggaaga tatttccgac tgcaaggatg gtcaatacag ttacaagcgg
     5401 agtcaactga ggaatggtta cgttgcgaat acgttgccac ttgctagctc cgtccactgt
     5461 cgctgcttcg tagtaggttg gatcaattcc catgatcgtc gcatagtaca tgacactgct
     5521 atatccaaaa cctttccaaa tacctaggaa aagtaggaga tagggccaga tgcccaggtc
     5581 agcgtagaaa ttgacttctt tgagaccaag actttccaat agatgattga acaccccttt
     5641 atcaatattt aggaaggcat ctgtaaagaa actgatgata acccaagaca agaagtaagg
     5701 gaacaacata gaagtttgga aaatcttcac cattctctta gaacggagct cgctgaggat
     5761 aatggcaatc cctacagata caactaaacc tagaaagata aagccaagat tgtagaggac
     5821 agtatttcgt gtgataataa aggcgtctct tgaactaaat aagaatctga aattatcgag
     5881 tccgacccat ttactattta tgatactatc tatgaaacca ttactggtca tgtggtagtc
     5941 tttgaaggca accacgttcc caaatactgg aatgtaaaag aatagaatca accagagtgc
     6001 ccctggcaaa accatcaaga gaaagatcca gttgtctctc aatgtttttg aaaacttttt
     6061 cataatttcc tcccttttta ttttgatatc catctaaaaa ttctttttta gacttttgat
     6121 aacgattaca ttattagtat actcctattt gcaggttagg ttaaactcct aattatagaa
     6181 aaaactccac aaattatgta gcagatttaa aactttatca ccactatcaa acaaatgtcc
     6241 taaatcaatt gtttatttta tctctattag cccagtgatg gcgtcactct gttataagca
     6301 tccaacaacg gggtatactg aaaaatctcc agactaggga actcagcgat agttcctaat
     6361 ctggagattt ttaatatgtt attaggcgtt tgctttcaac ttagcaataa cctctttaag
     6421 attatcaatc aactctgctg cagtatgctc agagcctttt tcatctgcca agaacaaaac
     6481 tgctttttga agttcttctt gagagttttc aaggacatcc ttatctgctg tttctttgcc
     6541 cgctgtttgt cctccatcct tagttgctga ctggctttcc ttaatggact ctagggaagc
     6601 aatggcatct ttgactgttt gcaagatatc acgtaaacct tgctctgtca aactatcatc
     6661 tgcaaaagct ttcttagcct ctgccaaaac cagaggtgct gaatctgtgg taggattcga
     6721 tacacctgtc aatgatctca aaagattttc taaggtttga gtctgcttac taatactaga
     6781 ctaaaatcaa aaagcattat ataacagtga tatgaaatca actaaagaag aaatccaaac
     6841 catcaaaaca cttttaaaag actctcgtac agctaaatat cataaacgcc ttcaaatcgt
     6901 tctatagtaa aatgaaacaa gaacaggaca aatcgatcag gacagtcaaa tcgatttcta
     6961 acaatgtttt agaagtagag gtgtactatt ctagtttcaa tccattatat ttcgtctgat
     7021 gggcaaatct tataaagaga ttatagaact tttatagtag tttgaaataa gatgtgaaca
     7081 actctatcag gaaagtcaaa ttaatttata gaaatatttt agcagccaag gtgtactgtt
     7141 atagattcaa tacactatac ttggtggttt agctctcctg ttttctcttt tagctttaac
     7201 cagccataaa tggtattacg tgagatttgg aaaacgtgtg atgcttctgt tatactacct
     7261 gttcgctcac aataagagag aactttttta cgaaaatcta ttgaatatgc cataaaaaga
     7321 ttataccaca ttgtgtacta tttttggttc actttactat atcactttgg actatatcgg
     7381 tctagttatg tctaaacgat tatagctgga tactaagaga aatcaaaaaa gcactaaggg
     7441 agaacgtccc aaagtgctta atatcaaggc ctcaaagcct atcttattca ataaaatatt
     7501 acaacatttt gttgtagaat tcaacgacaa gtgcttcgtt gatttctggg ttgatttcgt
     7561 cgcgttctgg caagcgagtc aatgaacctt ccaacttttc agcgtcgaat gatacgaatg
     7621 ctggacgtcc aagagtagct tctactgctt caaggattgc tggaactttc aatgattttt
     7681 cacgaactga gatcacttga cctggagtta cgcggtatga tgggatatca acgcgtttcc
     7741 cgtcaacaag gatgtgaccg tggtttacga attgacgagc ttgacgacga gtagtcgcga
     7801 gaccaagacg gtaaacaacg ttatccaaac gacgttccaa aagaagcata aagttgaaac
     7861 ctaggattcc gcctttgatt tttgtagctt gtacgaacaa gttacggaat tgtttttcac
     7921 ctacaccgta agtgaaacga agtttttgtt tttcagccaa ttgcaaaccg tattctgaca
     7981 atttagaacg gttgtttggt ccgtgttgtc ctggtacgta gttacgacgt gccaattctt
     8041 tacctgtacc tgtaagtgaa aggccaaggc gacgagcttg tttccaagat ggtcctgtat
     8101 aacgtgacat atgaatgtcc tcctgatata aataatattt cggtggaaat agtcacttag
     8161 aaagccctga ttcgtgcaga tgcccttcgc ctaaacagcc aaggttactt atcataagac
     8221 acctgttgac gagcttcatg ctttcctgct gatatttcac acaaggtcca ttttaccatg
     8281 aatagctgga tttgtaaagg ggttttaggc tttattttca ctaccagaga ggttgagaac
     8341 gagggtaaag gtacttccta gaccgtactg gctgctgact gtgatttccc cacccaattg
     8401 atgggccaat tcacgcgcaa tcgcaagtcc taatccatga ccacctgtct tcatgttacg
     8461 cgaagtttcg acacgataaa ggcgtttgaa aatattttcc aaatcctctg gggcaatgcc
     8521 ctgcccttca tcggtcacac tgattgaaag ctggcccttc tccagcttag ccaccacttc
     8581 cagcttggtt cctggagcag aatatttaaa agcgttatcg accagattca ccaagatacg
     8641 agaaagctta gcataatctc cctcaatccg ggcagactct gggattacct gcaagtggac
     8701 atctcttctc tcctgctcaa tcaaaaactg aaattcactc atgcactcaa ttaagagctt
     8761 gtccagaaaa atactgtctt tactggtagt ttccacctga tttctagctg tgtttagggt
     8821 caaaaaattc aactcctcaa ccagtttatt gagcctctcc gtctggcgtc caatggttgc
     8881 tagataatga gcttgctccg actccttgat aatcccatcc aaaatccctt ctaccgtcgc
     8941 ttggatcgaa gtgataggag tcttaatatc atgcgacaac tgggcaatca tcaagccctt
     9001 ttctcgttcg ctttcttcca aggaatcaaa gcttacctgc aaatcatggg acatctcatt
     9061 aaaagtttgc cctaattgct gaaattctac aggaccttga acctccaaat ttgaaggaaa
     9121 atccttggcc gctacccgct tggcatgctc cttgagtttg cccaacgacg taaagactgg
     9181 caataggaga aagagactaa tcccagcacc gacaaggctg gcaacgatgg tcatcccaag
     9241 caaaaagtaa atctcgcctt tcgcaatcag cattttttga acagcccaaa aaacaaccaa
     9301 aatggttaag agggttgaaa taatatatcc aaccaaaata taacttttta gtttcatgtt
     9361 tgtcctctcg gtttctctat cttatatccc aacccccaaa ctgtcttaat agtgggcgtt
     9421 tggtcactac tatattttgc cagctcctgt cgaagagcat ggatatgcac attcaaggta
     9481 ttggtgtcat ccacgtagtc ttctttccag atcttttcat agaggtctgt cttggagaaa
     9541 actcgctctg gattgctagc taaaatccac agcaattcaa atgatttaac agttaaatcc
     9601 agcatttctt ctcctatttg aacttcatga ctactatgat tcatttttag attgccaagg
     9661 gaaatcagct ctgtttcgcc cccacgatga aggcggcgca aaatattgtg gacacgcaaa
     9721 accagctcac gtgggctaaa aggcttagca ataaaatcat ctgctcccaa gctcaggccg
     9781 taaatcttgt cctgttcact ggtcttagca gtaataaata ggaaaggctg ctctggtgat
     9841 aagtattgaa cctcactgat taaatcataa ccatccatcc gaggcatcat gacatctgtg
     9901 ataatcaaat caatcggttt tttcttgaac agctctagcg cttccagtcc atcatgggct
     9961 accaagacct gataacctgc ctgaattaag tatctctgat gaatatctgt gatttctacc
    10021 tcgtcgtcaa cgagtaaaat tgtctttccc atctgtctct cctttgataa aaacagtgct
    10081 atactgcttt aagtataaca ctatttttat tgttttacga tgattttaat ctgctattga
    10141 aagaaagtcc tgattgctga ttgagttgtt aaactaatct tagtcagccc actatccatc
    10201 atttatttcc ttagctgatt agttttcttc ttttttgttt ttcaaaccta gaccaccgag
    10261 taaacctgca agcgcaagcc caaggaaacc aatacttgcc attgatgttt gagtctcacc
    10321 agtatttggt agcatagctt tatcctctga catcatcgta tcagacatct tgttagcaga
    10381 agcagccatg ttttcacctg ccatcgtgtt ggtagaactt gtcatggtgt cagcaggcat
    10441 gctatctgta gtacctgtag catgattgtg attcatcgga gtcacgccag aaccagagtt
    10501 agaaggtgat aatgaaccat ttgctgtgtc tgatgtttct ttaacattta tcttaatagt
    10561 gactttttta gttgctacga tgttgtccaa atctggttta ccgtctttgt taccatagac
    10621 attgactgta gcactgtaag tttgagtacc atttgctcgg aactggtcaa tgagcgcttg
    10681 tttttctttg ccagctacat ttccgtccaa ggcta
//
LOCUS       DAVDHC010000054        10035 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVDHC010000054 DAVDHC010000000
VERSION     DAVDHC010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.054"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VUR43_002094"
     CDS             complement(103..1806)
                     /gene="ilvD"
                     /locus_tag="VUR43_002094"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET5413716.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(2039..2971)
                     /locus_tag="VUR43_002095"
     CDS             complement(2039..2971)
                     /locus_tag="VUR43_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET5413717.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2968..3825)
                     /locus_tag="VUR43_002096"
     CDS             complement(2968..3825)
                     /locus_tag="VUR43_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET5413718.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3829..5175)
                     /locus_tag="VUR43_002097"
     CDS             complement(3829..5175)
                     /locus_tag="VUR43_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET5413719.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(5188..5472)
                     /locus_tag="VUR43_002098"
     CDS             complement(5188..5472)
                     /locus_tag="VUR43_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET5413720.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5476..7506)
                     /locus_tag="VUR43_002099"
     CDS             complement(5476..7506)
                     /locus_tag="VUR43_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET5413721.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7697..8704
                     /locus_tag="VUR43_002100"
     CDS             7697..8704
                     /locus_tag="VUR43_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET5413722.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8707..8907
                     /locus_tag="VUR43_002101"
     CDS             8707..8907
                     /locus_tag="VUR43_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET5413723.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9059..9241
                     /gene="rpmF"
                     /locus_tag="VUR43_002102"
     CDS             9059..9241
                     /gene="rpmF"
                     /locus_tag="VUR43_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET5413724.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            9257..9406
                     /gene="rpmG"
                     /locus_tag="VUR43_002103"
     CDS             9257..9406
                     /gene="rpmG"
                     /locus_tag="VUR43_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET5413725.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9898..>10035)
                     /locus_tag="VUR43_002104"
     CDS             complement(9898..>10035)
                     /locus_tag="VUR43_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5413726.1"
                     /translation="ESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANGEWV
                     G"
BASE COUNT         3255 a         2132 c         1621 g         3027 t
ORIGIN      
        1 caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acctacggca
       61 aggcgacgtt gacgtgattt gaagagattt tcgagtatga gtttattttt tacctgactt
      121 gtccatattc cagaagtctg tcacggctcc gcgtgaagca gatgatacga tgtgggcata
      181 tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct tgcgtttttc
      241 aagttcttct tcggatacgg ccatagaaat ttctttggta tcttggtcaa ccgtaacgat
      301 atcgccggta cggagatagg caattggtcc accatcctga gcttcaggag cgatatgtcc
      361 aacaaccaga ccataagtac caccagagaa acgtccgtcc gtcaagaggg ccaccttatc
      421 tccctgacct ttaccaacaa tcattgaaga aagtgatagc atctcaggca taccaggacc
      481 acctttaggt ccaacaaaac gaacaacgac tacatcgcca tcaacgattt catctgtcag
      541 aacggcctga atcgcatctt cttctgagtc aaagacctta gctggcccaa cgtgacgacg
      601 cactttaaca cctgatacct tggcaactgc accgtcagga gcaaggttcc cgttcaagat
      661 gataagcgga ccatccgcac gttttggatt ttcaagtggc atgataactt tttggcctgg
      721 agtcaagtct gcaaagtcag ccaagttttc agctacagtc ttaccagtac atgtgatgcg
      781 atctccgtga aggaaaccat ttgccaacaa atacttcata accgcaggga caccaccgac
      841 ttcgtagagg tcttggaaga catactgacc agatggtttc aagtcggcca agtgaggcac
      901 acgttcttga atcgtattga agtcctcaag tgacaagtca acatttgcgg catgggcaat
      961 ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga gccatcgtta cagtgatagc
     1021 atcttcaaag gcttcacgag tcaagatatc tgatggtttg agaccaagtt ccaacatctt
     1081 aacaacagca cgtcctgctg cttcgatatc ttctttctta tcagctgatt cagctgggtg
     1141 agaggatgac cctggcaaac tcatccctag aacttcgata gcagttgcca tggtattagc
     1201 agtatacata ccaccacaac caccagggcc agggcaggca ttacattcaa gacgtttcac
     1261 gtcctcagct gtcatgtcac cgtggttcca ttttccgata ccttcaaaga cagaaaccaa
     1321 gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg cgaaaatagc
     1381 tgggatatcc atattagcaa tagcaatcat agatccaggc atgttcttgt cacagccacc
     1441 gatagcgacg aaggcatcca cgttgtgacc actcatagcc gcctcgatgg agtccgcgat
     1501 gatgtcacga gatgttagag agaaacgcat accaggcgtt cccatagcga tcccgtccgc
     1561 tacggtaatg gttccaaact gtacaggcca agcgcctgca gatttgacac cttctttagc
     1621 cagtttcccg aaatcatgca agtgaatgtt acatggtgta ttttccgccc aagtcgaaat
     1681 cactcccaca atcgatgttt caaagtcctt atctgtcata ccagtcgcac gaagcatagc
     1741 acggttaggt gatttaacca tgctgtcata aatgctactg cggtgacgtt tatctaattc
     1801 agtcatctta tccctcccat ttcagttttt actattatag cacaattttc gcatgaagaa
     1861 cagaataaaa ttcttgaatt ttcagaaaat tctatacaca tgtgaaatat ttaaaattaa
     1921 aaacaacaaa gcggattagt gcactttctg atgaccagaa tatgcttttt aatccgcttt
     1981 ctttaaataa cgtactgtaa tttttacaga aattctttca aataagtgta tttaacatct
     2041 atcttgcatt ataaatttct agaaccttct cttttatatt cgattcactc aaaccatact
     2101 cattaagaag ataatccatt ttccctactt gaccgaatct ttcttgaaca cccatccgat
     2161 gaatttttgt tattccatca tcagagaata attcacataa agcactgcca attccaccta
     2221 tctgattgtg gttttctaca gtaaatatag tttttccact taacattgtt tttatctgtt
     2281 ctggtatcgg tttgattcta aataaatcta tcacacctac tgaataacct aatttagaca
     2341 gttcatctgc aactcgaata cttggagcaa ccattatgcc agaagcaacg attacaagat
     2401 cttcaccatg ccttaactca atgtagcctt tagaaaaatc ttctccacct tgatacacag
     2461 gaactggagc ttttctaatt gttcgaatat attttagtcc ttttaagtct aatgtctggt
     2521 tcaatatttc acgaaattgg atatcatcag ttgcttcgaa aatgattgat ttaggaatta
     2581 aacgtaacaa tccaatttct tcaaatggca tatgtgttcc accattcatc tctgccgtta
     2641 ctcctgcatc tgatccaatc acagtggcat ccaattgtgc gtatccaaga gaaataaata
     2701 attgatcaaa tactcttcgt gaagcaaaag gaccaaatgt atgaagataa ggtctaaacc
     2761 cctgaataga caagcctgct gcaaggccga ccatttctgc ttccataatc ccaacattca
     2821 cataacggtc tccaaagtcc ttttcaagat tatgagtagc catcgaactt gacaaatcgg
     2881 cttctaagac tactatatca gaatcacttt gattagcctc taaaaggaag tctctatata
     2941 catgccgtaa ttctttcgta cttctcatca ttctgtttcc tccaattcct gacttaatct
     3001 ttctacaact gaagttaaca tttgtttctc ctctacagta gggcgaagat gatgattgga
     3061 tttcatttct tccagctctt gaaccccttg acctttaata gtatctaata caatgcactt
     3121 aggtgatgaa ttatttgact gttttaattg gacaatccct tcataaattt ctctaatatc
     3181 tgaacccttg accctaatgg attcaaatcc aaatgctgaa aatttttcta cgaaatcacc
     3241 tggattacaa atatcctttg taaaaccatc taattgtttt ttgttatcat caacaaatac
     3301 aattaagttg gataactgtt gatgagaagc aaactgtata gcctcccaac attgtccctc
     3361 atttaactca ccatctccaa caatagcata agtataaaag ggactctttc ttattctctg
     3421 accatatgca agtccagttg caacactaat tccttgtcct aaagagcccg ttgtcatatc
     3481 tatgcctggc gttagatttc tatcaggatg agacggtaat ttggttccat ttgtatttaa
     3541 agaatataag aattctttgt caaagaaacc attcaaatag agtgtactgt atagagctgg
     3601 tcctccgtga ccttttgata atatgaaata atctctatct cgtgctgcaa atatttctgg
     3661 agtcattggc attatttcac cataaagcac cgctaaaact tctacgatag acagacttcc
     3721 tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga gtatttaatc ggatgttagt
     3781 cgcaaatttt cttaacccat cttctctatt tttacttaaa atcatccctt attcctccgt
     3841 tgcagatggc tttttaataa aggatactcc aaacataact gctagaataa gaacaagacc
     3901 aatcacaatg cctgcttgtg agccaaattg atttaacatt cctaaaataa ttcctgatag
     3961 accaaaatct gcatctgaga aagttgatcc ttggaaacca agtcctccca aaactggcat
     4021 taaaaagact ggaagaaaac tgattaaaat accttgtaaa aatgctccaa tagtggctcc
     4081 acgaacacca ccagatgcat tcccaatgac acctgcagtc gctccacaga agaaatgagg
     4141 cacaacacct ggtaagataa caaccgttcc tgaagcaatc ataattgcca tacttactaa
     4201 accaccaaca aaactagaga taaatccaat tagaactgca ttgggtgcat aagtataaac
     4261 aatcggacaa tccaaagcag gttttgaatt aggtacaaga cgctctgaaa tacctttaaa
     4321 ggctggaaca atttcgccca aaataaggcg aacacctgct aaaataacaa atacccctgc
     4381 tgcaaattga cctgctaatt gtaaagcata aactagacca cttgtaccac tactgatttc
     4441 tttttctata tattctgacc ctgcaaagat agctacaata atgtaaataa ctgccataga
     4501 taaagtgata ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa atttaatatc
     4561 ctctgttgat tttgatttgt caccgataag gctaccagta aaaccactca accaatatcc
     4621 caaagaactg aaatgaccta aagccacctt gtcatttcca gttaattgaa ccatatattt
     4681 ttgcacaaat gctggggaaa tactcataat aataccgagt gctaatcctc ctagtaagat
     4741 gagaggcaag ctagtaaagc cagcaactga taaaatgacc gcaatcatac atgccatata
     4801 tagagtgtgg tgccctgtta aaaaaatata tttaaatcga gtaaaacgag cgattaagat
     4861 attgaatacc atgcctgcaa acataatcat tgcagtagct gagccatatg ttgttaaagc
     4921 tacagctaca attgcttcat tattcggcac aacgccagat aaatgaaaag catgctcaaa
     4981 catggtacca aatggattta aagaattttg tacaattcct gcaccaccag atacaactaa
     5041 gaaaccaaca aaggtcttaa ttccaccttt aataatatct ggtaatttct tcttctgaag
     5101 aactaatcct aagattgcaa ttaaagctac taaaatagct ggtgtactaa caatatccaa
     5161 tatgaacttc atcatgacgc tagcctccta tataagtcct ttttcttcac aaagtttagt
     5221 aattaattct cgtagttcat ccatatcaat aatactattt aagatacgaa catctccaag
     5281 atgactagct gaatcagcta gatcacgacc aacaatccaa atatcagctg catttggatc
     5341 tgctccacct aaatcataat gttcaacttc tacatccgaa acattcaaat cactcaatac
     5401 agattcaata ttcatctgta ccataaaact tgaacctaat cctgaaccac aagctgtacc
     5461 aatttttaac attatctaat cctcctgttt aattatcatt ttaatgtcat catagttttt
     5521 tgatgatatt aaagtttgaa catgattttt atctcttaaa attgttgtta aatgtgacaa
     5581 agcctttaaa tgactctcat tatcaatggc tgcaatacaa atcaacaatc ttacctcttg
     5641 ttctggatta tccaataaat aaatcggttc ttccaaaact aacattgaca ttcctatttc
     5701 attcacacct tcatctggcc gagcgtgagg aattgctact cccttcccta aattaataaa
     5761 aggtccaaac tcttctactt tttgaatcat tgcctcaggg tagttctcag ttatcttatc
     5821 ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc ttccatccta atttttgcga
     5881 actaacctga taggtttctt tggtaataag ttgttctagc actggtacaa tttcctttct
     5941 atcatttttt tgataaagat aattctttaa cgccaatctt aattccaatt cttgtgtaat
     6001 aattccatat cttttgacaa tattcaggat ttgttcaatc tcaaaatctc catactctaa
     6061 attcggaaaa tcttttaaca ctagttctac tagttgtatt gcttgctctt cagtcatcat
     6121 aaccgaaact agataatttg gcttttctgt ctccaccttt atggtagaaa aaaccatatc
     6181 atagtcacta ctagctttca cctgtaaatc atcaatcttt gaggttccta taaactcaat
     6241 ttgaggaaat aatgctaata gattctcttt taacatcaat gaagaactaa caccattagg
     6301 acaaatgatt gctgctttat accatttttg aggcaaagta tctgctttct ttaaataacc
     6361 tccgaaatgg ataacaaaat atgctgtttc actatcaggt atgggattgt caatagcgtc
     6421 catcaagggc atcaaagaat ctttgactaa ttcaaataaa tcaggataat gttctttaac
     6481 atgcaataca tattcatttg aactaggtag gccgaacttt aatctatagt aagccggtat
     6541 aaggtggcga cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta acaaagaaat
     6601 atcttccatt ctacttataa tagcctctgt taattgatta aagtaaaccg gagcaacatc
     6661 tacttcacct tcaaagcaac ttgataataa aactgtgata tagcgataat catcctcaga
     6721 aaacaccgta tctataattc ccaaatcaac cactgtatcc aataaaatag tcgttatatc
     6781 ttgaataaca ggagatacta atgtctctga aagacatact ctttcaacat ccctttgata
     6841 cctacacaga atgaatacta aaccgaaaag gtaaactttt aattgattaa caataggtac
     6901 tagctgtagc ttctcataat aatctttaac tacctgatca atcaaatcat aagttaatga
     6961 atacccccaa ctggataaaa cataatccaa accccaaatc cctatggagg attccagcaa
     7021 ctcactaacc atttgaaaag ctaaacggtg cttattccac tctgaaccgt gtaaagtata
     7081 accttttgct ctactgtacc ctagctccaa atcattatct aacataatct ttcttaatga
     7141 ttgaatatca gataaggttg tattcttact tactttcaaa aagtcttggt aatgattatt
     7201 cgatataaaa tctaatcggc aaaaagtgta aagatagatt aaagctaagc gagtcgactt
     7261 tggtaaaacc aattcatccg acttaataat atctgtcaaa gactgcttcg tacgatttga
     7321 taaactatag cgaccttgtt ttttatccag cactatccct ttattagcta gataaggcac
     7381 taaataatct attccttctt tgacttcctt tataggtaag ctcaccttaa cagataattc
     7441 atataatgat agctcacaat gatccatcaa agtcatcaaa ataactagtg ctctataatc
     7501 aaacatttct cttcctttct aactacaatt atagtgtaaa aattataaga ataaaagagt
     7561 atttgagcac aatataatct caccttttaa aagaaattat tgggctgaaa ctttttagtg
     7621 attattttca actttctatt gacttttaaa aacaaagtga tatcatttag atatcaaata
     7681 atgggaggtc attcttatga ctgaaaaact aatcaattca aaaccaaatg gtgtattcgc
     7741 attgattctc attgagttga caatcgtact tggtatcttt atatttataa tgggggttgg
     7801 ttcggaaaac atttttggaa ttattatcgg acctttacta atcgtaattg caggtctagc
     7861 tcatgctggt ttaaaagttg tcaaacctca agaagctctg gttctgacac tctttggtaa
     7921 ctatacaggt accatcaaag aacctggctt ttactttgtc aatcccttca gcgtagcagt
     7981 caaccctgca aaccacactc gacttggaca aagtggtgat gttagcacaa aatctccttt
     8041 tttaggagct aaatcatcaa atgacaatga tgtaaatctt gaaattggca agaaacagat
     8101 ttccctcaaa gtcatgacct tgagcaattc tcgtcaaaaa atcaatgatt gcttaggaaa
     8161 ccctgtagaa atcggtatcg cggtaacttg gagagttgtc gataccgcta aggcagtctt
     8221 caacgttgat aactacaaag aatatctttc attgcaatgt gatagcgccc tccgtaatat
     8281 tgtccgcatc tatccttacg atgtgtctcc taatgtggat actacgggtg atgggcaagc
     8341 agatgaaggt agtctccgtg gctctagcga aattgttgct aaccgtattc gtgaagaaat
     8401 ccaaagtcgt gttgaggatg ctggcttgga aatccttgaa gcacgtatca cttacctagc
     8461 ttatgctcca gaaattgctg ccgttatgct tcaacgccaa caagcatctg ccattattga
     8521 tgcacggaag atgattgtag atggtgctgt aggaatggtt gaaatggcac tagaacggct
     8581 caatgaaggg gaattggtag aacttgacga agaacgaaaa gctgccatgg tttcaaatct
     8641 ccttgtcgtt ctttgtggca atcatgatgc acaaccaatt gtcaacacag gaagccttta
     8701 ctaaagatgg ctgaagctaa aaaaaagcag atcccccttc gactctcaac aaagttatac
     8761 gctgcactcg catcatgggc agaagacgac tttcgttcag tcaatgggca aatcgaatat
     8821 ctcctcacag agtgtgtcaa gcaacggaag aaagacggaa aatacgtatc agaaaccatt
     8881 gacgaaccat ttgagattga tatttaacac cttctcctgt ctgccgtgtc ggataggaga
     8941 attttttcat ctttttttgt caagtaactt tactttacaa aaaaaatgtg ttatcctagt
     9001 atggttgatg aaaatcagta gattgaatcg aatataaata cctaaaggag aaatcaaaat
     9061 ggcagtacct gcacgtcgca cttcaaaagc gaagaaaaac aaacgtcgta cacactacaa
     9121 agtaacagct ccatctgtaa actttgacga aactactgga gattactcac gttctcaccg
     9181 tgtatcactt aaaggatact acaaaggacg taaaatcact aaagctgcat cagctgaata
     9241 atagaaggga gataccatgc gcgtaaatat tacacttgaa cacaaagaat ctggtgaacg
     9301 cttgtacctt acttctaaaa acaaacgtaa cactccagac cgccttcaat tgaagaaata
     9361 ctcaccaaaa cttcgcaaac acgttgtgtt tacagaggtt aaataagcat tcaatacgaa
     9421 tcaatacaga agaaaaacgc ttgatcagcg ttttttcttt ttgttaattt cactacattg
     9481 taagggaaat cattcgaatg actacatttt tcactacctt ttttgaaata agaatacgga
     9541 ttcggacaat taaaagcaag aggaactcaa atgtaagttg gggttccttt tttgtatatt
     9601 tttcaaataa cgcctctaca ctatttgtag caaattcacc aactacagtt gtatcttagt
     9661 taaaataagt tagaatatgt aagtgagtac cagatatacc aagacatcgt caccatctaa
     9721 ggtatattca aaatacaaaa gttgaccaac tagatttctg aatatcctta tatatccatt
     9781 cttaaaattg gtttaaatag cgtagtcttt taaactagtt ttgagaatcc aaaaaatctt
     9841 cctacatatg taagaagatt ttttagttca gaatgattag atttagctaa tggataccta
     9901 tcctacccac tcaccgttag cattgactcg atagccatcg ggtgtagtcg tgtttactaa
     9961 taaatctcct gaattatagg tatagtacca tttaccagaa actgtaaccc aaccagtagc
    10021 cattgaacct gattc
//
LOCUS       DAVDHC010000055         9885 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVDHC010000055 DAVDHC010000000
VERSION     DAVDHC010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9885
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.055"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            244..2172
                     /gene="glgB"
                     /locus_tag="VUR43_002105"
     CDS             244..2172
                     /gene="glgB"
                     /locus_tag="VUR43_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET5413727.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2162..3304
                     /locus_tag="VUR43_002106"
     CDS             2162..3304
                     /locus_tag="VUR43_002106"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET5413728.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3294..4433
                     /gene="glgD"
                     /locus_tag="VUR43_002107"
     CDS             3294..4433
                     /gene="glgD"
                     /locus_tag="VUR43_002107"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET5413729.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4430..5863
                     /gene="glgA"
                     /locus_tag="VUR43_002108"
     CDS             4430..5863
                     /gene="glgA"
                     /locus_tag="VUR43_002108"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET5413730.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5922..6293
                     /locus_tag="VUR43_002109"
     CDS             5922..6293
                     /locus_tag="VUR43_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET5413731.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6238..6567
                     /locus_tag="VUR43_002110"
     CDS             6238..6567
                     /locus_tag="VUR43_002110"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET5413732.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERMVAIGDGVNNLLMLKSAELGIAFCAKEVLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            6576..7691
                     /locus_tag="VUR43_002111"
     CDS             6576..7691
                     /locus_tag="VUR43_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET5413733.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGYQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(7688..8134)
                     /locus_tag="VUR43_002112"
     CDS             complement(7688..8134)
                     /locus_tag="VUR43_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET5413734.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8298..9602
                     /gene="eno"
                     /locus_tag="VUR43_002113"
     CDS             8298..9602
                     /gene="eno"
                     /locus_tag="VUR43_002113"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET5413735.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9740..>9885)
                     /locus_tag="VUR43_002114"
     CDS             complement(9740..>9885)
                     /locus_tag="VUR43_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HET5413736.1"
                     /translation="NKIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMK
                     KIF"
BASE COUNT         2974 a         1747 c         2175 g         2989 t
ORIGIN      
        1 attgttagaa attagattaa attccttaat cgatttgcgc atgttttatt tcatttcact
       61 atagtagaaa aagaaaggtg ttttcgcaat tttttgaaaa aatattgatt tacaattgaa
      121 cgagtaagtg aacttgttgt agattttcaa aataattaaa gaagtatagt aatttacttg
      181 aatcttctct aaaaaggtag tataataaaa acatagaaaa cgcttacagg aaaaagggag
      241 tatatggata atagagaagc attaaaaacc tttatgacgg gtgaaaattt ttatctccaa
      301 cattatctag gagcacatag ggaagaacta aatggagagc atggctatac cttccgtgtt
      361 tgggcaccta atgctcaggc tgttcacttg gttggtgatt ttaccaactg gattgaaaat
      421 cagattccaa tggtaagaaa tgattttggg gtctgggaag tctttaccaa tatggctcaa
      481 gaagggcata tttacaaata tcatgtcaca cgtcaaaatg gtcatcaact gatgaagatt
      541 gacccttttg ctgtcaggta tgaggctcgt ccaggaacag gggcaatctt aacagagctt
      601 cctgagaaga aatggaagga tggactttgg ctggcacgaa gaaaacgttg gggctttgaa
      661 gagcgtcctg tcaatattta tgaagttcac gctggatcat ggaaaagaaa ttctgatggc
      721 agtccttata gttttgccca attgaaagat gaactcattc cttacctagt tgagatgaac
      781 tatactcata ttgagtttat gcccttgatg tcccacccac taggtttgag ttgggggtac
      841 cagcttatgg gttacttcgc tttagagcat gcctatggta gaccagagga gtttcaagat
      901 tttgtcgagg agtgtcatac ccataatatt ggggttattg tggactgggt accaggtcac
      961 tttaccatca atgatgatgc cttagcctat tatgatggga caccgacttt tgaataccaa
     1021 gaccataata aggctcataa ccatggttgg ggtgccctta attttgacct tggaaaaaat
     1081 gaagtccagt ccttcttaat ttcttgcatt aagcattgga ttgatatcta tcatttggat
     1141 ggtattcgtg tggatgctgt tagcaacatg ctctatttgg actatgatga tgctccatgg
     1201 acacctaata aagatggcgg aaatctcaac tatgaaggtt attatttcct tcaacgcttg
     1261 aatgaagtta ttaagttaga atatccagat gtgatgatga ttgcagaaga aagttcgtct
     1321 gcaaccaaga ttacgggaat gaaagagatt ggtggtctag gatttgacta caaatggaac
     1381 atgggctgga tgaatgatat cctccgtttc tacgaagaag atccgattta tcgtaaatat
     1441 gactttaacc tggtgacttt cagctttatg tatgttttca aggagaatta tctcttgcca
     1501 ttctcgcacg atgaagtggt tcatggcaag aagagtatga tgcataagat gtggggagat
     1561 cgttacaatc aattcgcagg cttgcgcaat ctctatacgt accaaatttg tcaccctggt
     1621 aagaaattgc tcttcatggg tagcgaatac ggtcaattcc tagaatggaa atctgaagaa
     1681 cagttggaat ggtctaacct agaagaccca atgaatgcta agatgaagta tttcacttct
     1741 cagctaaacc agttttacaa agatcatcgc tgtctgtggg aaatcgatac cagctatgat
     1801 ggtattgaaa tcattgatgc ggataatcga gaccagagtg ttctttcctt tattcgtaag
     1861 ggtaaaaagg gagaaatgtt agtctgtatc tttaacatgg tacctgttga gcggaaagat
     1921 tttacaatcg gactacccgt tgcaggaatt tacgaagaag tatggaatac tgagttggaa
     1981 gagtggggag gcgtttggaa agaacataat caaactgttc aaacgcaaga aggactatgg
     2041 aaagattatg agcagacctt aacctttacc ctaccggcta tgggagcaag tgtatggaaa
     2101 atcaaacgtc gcttgaaatc tactaaaacc gtcacaaata aaaaccaaaa aggagtagaa
     2161 aatgaaaaat gaaatgttag ctttgattct tgctggtggg caaggaactc gtctcggtaa
     2221 actcactcaa agcatcgcaa aaccagctgt gcaatttggt gggcgctacc gtatcattga
     2281 ctttgcccta tcaaactgtg ccaactcagg gattcacaat gttggggtcg ttacacagta
     2341 tcaaccactt gctctcaaca accatattgg gaatggttca agctggggac tagacggtat
     2401 taattcaggt gtctctattc ttcaacctta ttctgcaagt gaaggaaatc gttggtttga
     2461 ggggactagt cacgctattt accaaaatat cgactatatc gacagtgtca atcctgagta
     2521 tgtcttgatt ttgtctgggg atcacatcta caaaatggac tatgatgata tgctccagtc
     2581 tcataaggat aataatgcca gcttgacagt agcagtttta gacgtccctc ttaaagaagc
     2641 aagccgtttt ggtatcatga acacagatgc taacaatcgt attgttgaat ttgaagaaaa
     2701 accagctcaa cctaaatcta caaaagcttc tatgggaatc tacatttttg attggcaacg
     2761 ccttcgtaat atgttagtcg ctgctgaaaa gagcaaggtt ggcatgtcag actttggtaa
     2821 aaatgtcatt ccaaattacc ttgagtcagg tgaaagtgtt tatgcttacg aatttagtgg
     2881 ttattggaaa gatgttggta ctattgagtc actttgggaa gcgaacatgg agtatatttc
     2941 tccagaaaat gccttggata gtcgtaaccg tcaatggaag atttactcaa gaaacttgat
     3001 ttcaccacca aacttcctcg gggcaaatgc tcatgtggaa gactcattag ttgtagacgg
     3061 atgtttcgtt gatggaactg ttaaacattc tatcctttca acaggcgcgc aagttcgcga
     3121 aggagcggaa gtccttgatt cagttatcat gagtggagct atcattggtc aaggagctaa
     3181 gattaaacgt gccattattg gtgaaggtgc gattatttct gacggtgtcg aaattgatgg
     3241 aacagatgaa gtacaagttg taggatataa tgaagtagtg ggggtagcaa cagatgaaga
     3301 ttgataaata ttctgccatt ttaggaaata cagttggttt tcacaatatg tcgacattga
     3361 cggaccaccg tccagtagca agtttgccat ttggtgggaa atatcgtttg attgacttcc
     3421 cactttcaag ccttgctaat gcaggtgttc gtagtgtctt tggtattttc cagcaggata
     3481 atatcagctc agtatttgac catattcgtt caggacgcga gtggggctta tcaacccttc
     3541 ttagccatta ctatctagga atttacaata cccgtgtaga aagtagtaca gttggaaaag
     3601 aatactacca acagcttctt acttatttga aacgttctgg ctcaaaccaa acggttgccc
     3661 tcaactgcga tgttcttatt aacattgatt tgaaccaagt tttccaccta catagtacaa
     3721 caaaagagcc tatcactgta gtttataaaa aactagctaa gaaagatatt tcagaagtaa
     3781 atgcaatctt ggatgtagat gaaacagacc atgttctttc tcataaactc tttgatagca
     3841 agtcaacagc tgaaacgttc aatatgtcta cagatatctt tgtcgttgat acaccttggt
     3901 tgattgaaca cttggaagaa gaagctaaaa aagaacatcc agagaaattg cgctatgttt
     3961 tacgggattt ggctgtaaaa gagggagctt tcgcctacga gtacacgggc tatctagcca
     4021 atattcactc tgttaaatct tattatcaag cgaatatcga tatgcttgaa tcacaaaaat
     4081 tctattctct tttctcacca aaccaaaaga tttatacaaa ggtcaaaaac gaagagccaa
     4141 cttactatgc taatacatct aaggtaagca cttctcagtt tgcctctggt agtattattg
     4201 aaggtcaagt agctaattct gttctatcac gtaatattca tgtccataag gatagcttgg
     4261 ttaaagatag cctgctcttc cctcgtgttg ttattggaga aggggctcag gtcgaatatg
     4321 ctatcttgga caaaggggtt gaagttgagc ctggtgttgt gattcgagga actgcagaac
     4381 atccagttgt ggttaagaaa ggtgctaaag taacagagga tattcattca tgaaaatttt
     4441 atttgtagca gcagagggtg cacccttttc aaaaacaggt ggtttgggag acgtcattgg
     4501 cgctcttcca aaatcactgg taaaagctgg gcacgaagtt gcagtgattt taccctacta
     4561 tgatatggta gaggctaaat ttggaagtca gattgaagat gtgcttcatt ttgaggtgag
     4621 cgttggttgg cgcagacagt attgtggaat taagaaaaca gtattaaatg gtgtaacctt
     4681 ctactttatt gacaatcaat attatttctt ccgtggtcat gtttacggtg attttgatga
     4741 cggagaacgc tttgcctttt tccaactggc tgccattgag gctatggaaa ggattgactt
     4801 tattcctgat cttctccatg ttcatgacta ccatacagct atgattcctt tcttgttgaa
     4861 ggaaaaatac cgttggattc aagcctatga ggacattgaa acagttttaa ccattcataa
     4921 tttagaattc caaggacaat tttcagaagg aatgttgggt gatttgtttg gagttggctt
     4981 tgaacgttac gctgatggca cccttcgatg gaacaactgt ctgaactgga tgaaggcagg
     5041 tattctctat gcgaaccgtg tttcaactgt ttcacctagc tatgctcatg aaattatgac
     5101 tagtcagttt ggatgtaatt tggatcagat tcttaaaatg gagtctggta aagtatctgg
     5161 tatcgtgaat gggattgatg ctgatcttta taatcctcag acggatgctc ttttagacta
     5221 tcatttcaat caggaagatt tgtctgggaa agccaaaaat aaggcaaaat tgcaagaaag
     5281 agttggcttg cctgttagag cagacgttcc actggtggga attgtttctc gtttgacacg
     5341 tcaaaaaggt tttgatgtgg tggtcgaaag tcttcaccat atcttgcaag aagatgttca
     5401 gattgttctt ttgggaactg gcgatccagc ctttgaagga gctttctcat ggtttgctca
     5461 gatttaccca gacaagctat caacaaatat cacttttgat gtcaaacttg ctcaggaaat
     5521 ctacgctgct tgtgacctct tcctcatgcc aagtcgtttt gaaccgtgtg gcttgtctca
     5581 aatgatggct atgcgttatg gaaccttgcc attggtccat gaagttggag gcttgcgaga
     5641 tacagttcgc gctttcaatc caatcgaagg aagcggtact ggctttagct ttgacaatct
     5701 atctccttat tggttaaatt ggactttcca aacagcattg gacttgtata gaaaccatcc
     5761 agacatttgg agaaacctac aaaaacaagc tatggagagt gacttctcat gggatacagc
     5821 ctgcaagtca taccttgact tgtaccatag tttagttaat taatagataa aatcgtatga
     5881 tgacttcata cgatttttag gctgtttaga gaggagaact gatgtctcaa gtaaaaggct
     5941 tgtgtgtttt ggatgtagat ggaaccttaa tcctagaaga agtgattgat cttttaggga
     6001 gagaggcagg tcatgaggcg gaaatttcgc agattacaag tcgagcaatg cgaggagagt
     6061 tggtctttga aagcagttta agaaaaagag tgtccttgtt ggaaggtctt cctattttgg
     6121 tctttgataa cgtcttcaac tcaattcatc tatcgctaaa tgtcccagag ttcatctcta
     6181 ttctccaaaa gaatggcatc ctagttggtc tggtgtctgg tggatttaca ccaatagttg
     6241 gagagattag caaaatccct tggtattgcc tatttcactg ccaaccagct tgaagtcaaa
     6301 gaaggtcttt taacaggaaa attagttgga caaattataa gtccccaggt caaaaaagaa
     6361 actctggaaa aatggagaaa gaaactaaaa ctttctaaag aaagaatggt ggcaatcggt
     6421 gatggggtca ataatctatt aatgttgaag tcggcggagt taggaatcgc cttttgtgcc
     6481 aaagaagtgc tcaaaaaaga aataccacat catgttgaca agagggattt tttagaagtt
     6541 cttcctttga ttgactgttt agaatgaggg aaaatatgaa gattgtaatt gcaccggatt
     6601 cgtttaagga aagcttgaca gctcaacagg tagctgaagc aataaaaaga ggcttccaac
     6661 aatcgatagc agatgtagaa tgtctcctct gccctgttgg tgatggggga gaaggtactg
     6721 tagatgctat ccgacattct cttgacctaa aagaaaaatg gatccaagtg acagaccctt
     6781 ttggacaaaa agaagccatg cgctattttc aaaaagggga actggcacta tttgaagtag
     6841 ctgacttggt tggtcttgga aaaattccgc tagagaaacg aaatccactt caaatccaaa
     6901 cttgtggtat tggagagttg attctccatc tcatttctaa agggattaaa gatatttata
     6961 tcggtgttgg tggcacggcc agtaatgatg gaggactggg gattgctgct ggtttaggtt
     7021 atcaatttta tgatagggat ggaaatgtct tgcctgcttc cggtcaatcc ttattaaact
     7081 tagcttctgt ttcaacagaa aatcgctata aaattcctga aggtgttcaa attcatattt
     7141 tagcagatgt cgtgagtccc ttatgtggtt atcaaggtgc gacttacact tttggcaatc
     7201 aaaaaggtct acatccgact atgtttgcag tcgtagatca ggcgatccaa gatttttatg
     7261 aaaaattctc acctgcaaca ttagaaatta aaggagcagg agcaggtgga ggccttgctg
     7321 gtggtttgtg tgcctttgct caggcaagta tcgtgtctgg aattgatacc tgcttggact
     7381 taatcaactt tgataagaaa gtttcagatg ctgacttggt tgttgttgga gaaggaagac
     7441 ttgacagtca aagctttgct gggaaagcgc ctataggtgt tgcaaaaaga acccctgttg
     7501 gagttcctgt tattgctatt tgcggtagtc ttgctgaaga tttacctccc ctaccatttg
     7561 aaaatatcca agctgtcttt tctattttgg agaaaagtga acctttagaa gatagtttga
     7621 aaaatgccag tctctatctg gagcgcacgg ctgccaatat tgggcactta ttaaatatgt
     7681 gcaagattta gctaaaccat ttcttccata aggatgtttt ggctggttct tcctttttaa
     7741 cttcccaaag ttttggaaaa gcaagtcgaa ggtctttttc ttctacttga actggtgcat
     7801 tgctatgaat aaccaggcca aaaggagaag taatatgctc ttcagatact atggtggctt
     7861 gactatcagt ttcttttgct tcttttaagt agaaaacttg cttatcaaat tcgatagttg
     7921 gtgaaatctt cacaaatagt ggctctgctt tttcctgaag gttttctaaa ataaataaaa
     7981 agcctttttc taactgaggg ctatttgctg tgtcaatatc tacatatcca agaactcttt
     8041 cctcaaaagt accaagatag cgtctttgct catccggatt tatttttaac ccaccatgag
     8101 ctttttcaag taattgtttt gataaatctg tcatgaaaac agtatatcat aaaagttaga
     8161 ataaaacaga caaaagaaag cgattacttt ataaagttaa ggaaaagttg cacaaagata
     8221 acgttttttc ttgaaaaagg aggggtttta aggtattata gaggtgtaaa aaatttaact
     8281 cataaggaga gtaaaaaatg tcaattatta ctgatgttta cgctcgcgaa gtcctagact
     8341 cacgcggtaa cccaacactt gaagtagaag tttacactga atcaggtgct ttcggacgtg
     8401 gtatggttcc atcaggagct tctactggtg aacacgaagc agttgaactt cgcgacggtg
     8461 acaaatctcg ttacggtggt cttggtacac aaaaagctgt tgacaacgta aataacatca
     8521 ttgctgaagc tatcattggc tacgatgtac gtgatcaaca agctattgac cgtgctatga
     8581 tcgcacttga cggtactcct aacaaaggta aattgggtgc gaatgcaatc ctcggtgtgt
     8641 ctatcgctgt agctcgtgct gctgctgact accttgaaat cccactttac agctatcttg
     8701 gtggattcaa cactaaagtt cttccaactc caatgatgaa catcatcaac ggtggttctc
     8761 actctgacgc tccaatcgct ttccaagagt tcatgatctt gccagttggt gcgccaacat
     8821 ttaaagaagc ccttcgttac ggtgctgaaa tcttccacgc tcttaagaaa atccttaaat
     8881 cacgtggttt ggaaactgcc gtaggtgacg aaggtggatt cgctcctcgt ttcgaaggaa
     8941 ctgaagatgg tgttgaaact atccttgctg cgattgaagc tgctggatat gtaccaggta
     9001 aagacgtatt tatcggattt gactgtgctt catcagaatt ctacgataaa gaacgtaaag
     9061 tttacgacta cactaaattt gaaggtgaag gtgctgctgt tcgtacatct gcagaacaaa
     9121 tcgactacct tgaagaattg gttaacaaat acccaatcat cactattgaa gatggtatgg
     9181 atgaaaacga ctgggatggt tggaaagctc ttactgaacg tcttggtaag aaagtacaac
     9241 ttgttggtga cgacttcttc gtaacaaaca ctgactacct tgcacgtggt atccaagaag
     9301 gtgctgctaa ctcaatcctt atcaaagtta accaaatcgg tactcttact gaaacttttg
     9361 aagctatcga aatggctaaa gaagctggtt acactgctgt tgtatcacac cgttcaggtg
     9421 aaactgaaga ttcaacaatc gctgatattg cagttgcaac taacgcagga caaatcaaga
     9481 ctggttcact ttcacgtaca gaccgcatcg ctaaatacaa ccaattgctt cgtatcgaag
     9541 accaacttgg tgaagtagct gaatatcgtg gattgaaatc attctacaac cttaaaaaat
     9601 aaaatagttc agtgaactat tttatcccga accatgaaat tcaaaagttc ggccgttgat
     9661 ttaacaacgt ttctagcccc tcggatttta tccgaagggc tatttttgta tttagaggac
     9721 aaaaaaggga caaaactttt taaaaaatct ttttcataac tttatccagt acattgattg
     9781 cttcatcttt catgttcttt gtgacgtggg tgtagatgga agtagtgact tcagagtcgg
     9841 aatgaccaac cctgtccgtg attgttttta aaggaatttt attgg
//
LOCUS       DAVDHC010000056         9313 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVDHC010000056 DAVDHC010000000
VERSION     DAVDHC010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9313
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.056"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(76..309)
                     /locus_tag="VUR43_002115"
     CDS             complement(76..309)
                     /locus_tag="VUR43_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET5413737.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFNIEISDEEIDQLQSVGDVVKIIQGK"
     gene            complement(315..1307)
                     /gene="plsX"
                     /locus_tag="VUR43_002116"
     CDS             complement(315..1307)
                     /gene="plsX"
                     /locus_tag="VUR43_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET5413738.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALADFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRKKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTIDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAKPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1304..2074)
                     /gene="recO"
                     /locus_tag="VUR43_002117"
     CDS             complement(1304..2074)
                     /gene="recO"
                     /locus_tag="VUR43_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET5413739.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQAGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRIG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLEAISLKPEIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2071..3240)
                     /locus_tag="VUR43_002118"
     CDS             complement(2071..3240)
                     /locus_tag="VUR43_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET5413740.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PNHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASAFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIIEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3811..4821
                     /locus_tag="VUR43_002119"
     CDS             3811..4821
                     /locus_tag="VUR43_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET5413741.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYFFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTSLGIQILIG
                     IF"
     gene            complement(4993..5430)
                     /locus_tag="VUR43_002120"
     CDS             complement(4993..5430)
                     /locus_tag="VUR43_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET5413742.1"
                     /translation="MSQEFINPSDGVIRQYLAMSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKVAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVVRDFLKADT
                     KIFWAQLGLESLEAEEILRAGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(5515..8148)
                     /gene="polA"
                     /locus_tag="VUR43_002121"
     CDS             complement(5515..8148)
                     /gene="polA"
                     /locus_tag="VUR43_002121"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET5413743.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            8404..8754
                     /locus_tag="VUR43_002122"
     CDS             8404..8754
                     /locus_tag="VUR43_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET5413744.1"
                     /translation="MLRHPCISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWIYLCSQVN
                     QNLEKIRQREGDTH"
     gene            8969..9085
                     /locus_tag="VUR43_002123"
     CDS             8969..9085
                     /locus_tag="VUR43_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET5413745.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            9078..9311
                     /locus_tag="VUR43_002124"
     CDS             9078..9311
                     /locus_tag="VUR43_002124"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413746.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGREERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         2633 a         2278 c         1769 g         2633 t
ORIGIN      
        1 caagatttta ccagcttgtc cgatatttct catttctaaa aaccatctac ttccgttgac
       61 ttggaactcc gattgctatt ttccttgaat gattttaacc acatctccta cgctttggag
      121 ttggtcaatt tcctcatcgc tgatttcgat attaaattca tcttccagtg tcaagataaa
      181 ctccatcaag tcaacggagt cagcatccaa atcatctttc agactcaagg attctgtcac
      241 gacaaagtcc tctccctgtc gctcttggat aatggtcaca atacggtcaa aaatttcttt
      301 ttctgtcatc tcttttattc tcctgaaaat tcacgcgcag tctgggcaac tacgtctgtt
      361 tctagcatgg tacgaatctg gcggattgta ctataaacag ccttggcatc gcttgagcca
      421 tgagtcttga caacaggtgc cttgacacca aacaagaccg ctccaccaac atctgagtag
      481 ttgagctgtt ttttcaaacc tctgaggctg tccttgagaa ggagggcacc tagtttcgct
      541 cgaagaccac cacctgtaat agcggtcttg agcaagccca tgattcccat ggctgtccct
      601 tcgatggatt tgagcacagc gtttcccgtg aaaccatctg ccacgacaac atccgcaacg
      661 ccattcatca aatcacgtgc ttccacgttt ccgataaagt ttaaactttc atcagctgct
      721 agtaattcgt aagtttcctt acgaagcgga tcgcccttgc tactctctgt tccgttgttg
      781 agcaaaccaa cacgtggttt tgcaattcca cggacatttt tagcatagaa ggaacctaga
      841 accgcatatt gatggaggtg ctgggctgta ttttctgcat tagcaccgag gtcaagcatg
      901 tcaaaacctt tcccatcaat agtcggcaag gtagacataa gcccagggcg atcaatgttc
      961 ttgatacgac ccacgatgaa gaatccagcc gccaacaaag cacctgtatt cccagctgag
     1021 agaacagcat ctgcttctcc atctttgaca gccttggccg ccaataccat actagcattt
     1081 ttcttcttcc gaatagctct cgtaggttca tcgtctgaat caatcttttc atccgtatgg
     1141 atgatgctga cgcgctctgt cgctgtcaga tattgcttga ttttagcttc atctccgtag
     1201 agttgaacct cgatatctga aaagtcagct agggcttgat tgacaccctc aacgatggcc
     1261 tgaggtgcgt aatcgcctcc catggcatct actgcgattt ttttcatttc ttttcctctt
     1321 ttaataattg tccccagtct gctagggaat caataaattt ctttgatttt aggtgaatcc
     1381 caacgtactc ttcgtagagt tgatccataa attggcgtag ctcttgcttg atttcgggct
     1441 tgagcgaaat ggcctccaaa gtctcaaaat caatggcttg aaactgattg agcagatagg
     1501 ggatattggg gttgagatgg caacgtctct catcctcatg ataatgctct ggacagaggc
     1561 aggcgccata tttgaaagaa aagtcaaaag cctgaccgat ccgatgacag aagacacact
     1621 cattaaaatt gagactaatt ccaaatcgag tcaagatttg aatttcaaaa atattggtca
     1681 aaacctgata atccaaacct gcttccatca actccaaagt cttttgcaaa aaagcaaaca
     1741 agggagcatc ctgctgattg tcctgcaaac tagcatctgc aagagccgcc acataggtcg
     1801 cataggccat gacaaagaga tcgctattaa tcttgggaaa agtcatcacc tcatgatagt
     1861 cctcaatgta actgagcccg tcatcattga ttcgtaagag aaatcgagcc agcaccaagg
     1921 gctgaataac tggagccagc ttagactgac cagcgtgttt gacaaaaaac atgcgtttgc
     1981 cagcctgctc tgtaaaaatc ttgacgagct tgtcatcctc ccgaaagttg cgattgtaga
     2041 gcaccaagcc ttgactcgtg atagactgaa tcatgcttct ctcatgtact cctcaagccg
     2101 tttcatggct tctttgatcg tctccatgct ggctgcataa gacaagcgaa catagccttc
     2161 tccgtaacgc ccaaaggcag ctccagggat aaaggcaacg gccttcttct gagcaaaatc
     2221 cttgagaaag gcaaaggagt cttgattgta gcccgctgga atcttagcaa agatatagaa
     2281 ggcaccgtct ggtttgataa tctcaaaacc aagagcggtc atcttttcga tgatataatc
     2341 ccgacgctgg atgtattcct tcttcatagg ttccgcatcg tttttaccag ctgtcaaagc
     2401 ttccaccgca gcatgttgcg ccatggtatt tgctgcagtg accaagtact gatgactctt
     2461 gatcaattgg gctgtgaagg ccgcaggagc gaaaattaga cccaaacgcc aacctgtcat
     2521 ggcatgcgat ttagacaaac cattgataat aatagcctgg tctctcaaca tagttcccag
     2581 agacacatgg gcttcgcctg tgtaggtcaa ttctgagtaa acctcatcac agacaacgaa
     2641 aatctcgtac ttgcgtaaaa cagctgccaa ggcctccaac tgctcccgac tataggtaat
     2701 tcctgtcgga ttagccggat agttgagaat aaccgccttg agcttgtctc cctgctccaa
     2761 aatggccttt tccaacatct caggagtcaa gacaaaccca ttttcagtcg tgtcaatctc
     2821 gataatctct gccccaacta gattaacaat cggttcatag cctggatagg caggagctgg
     2881 caagagcacc ttgtctccct cttctaaaat agctgtcaaa gtagcagata aggcctctgt
     2941 cgccccaatt gtaaccaaga tttcattttc aggagcatag tccagttggt acttttcctt
     3001 aacaaaggca ctggctgcct gacgtagagt cagcaaacca ctcatccctg tatagtagga
     3061 ttggttctga tcaatcgctc gcttggccgc ctccttgaca tgatttggcg ttgtaaaatc
     3121 aggttccccc aaggtcaaac gcaagacccc aggaatctcc gaaatagcct ggtcaaactg
     3181 acgaatcaac gaaacttgaa tcttatctaa ctgtttatta aagcgcttag ttaagtccat
     3241 agatacctcc tactttcaaa acatatctct attatactac aaaagccccc cgaccgcaaa
     3301 aatacatgat agaataacgc tagcataaca aattgaagtg tgttaattta aattgattac
     3361 aacactatgt ttttagaata ctcaatgaaa atctcatgag actaggaatc gaggtgaaag
     3421 cataactaaa gttaggtaag ccgaagatga caacgtatca tgagattttc gacgagtatt
     3481 gaggttttga taatcttcgt tacaactatt ctagcaccat tactgattac tattaccggt
     3541 aatgtcattt ctgagtggat agtcagaaag tggttagata agcgcgacaa aaaaatataa
     3601 cctgagttta gttttaatgt aactggacaa aaagaaatac cagaggtgga gctctggtat
     3661 ttttgttttt gccaagactt cgttacagtt cttgtaagat tattattaca taattagcac
     3721 tacttgtcaa ataattgttg gctccacttt ctattttact tttcctgttt aaaggtctat
     3781 aatggtaaca gattttattt ggaggttttt atgtcatttc tatcaaaaaa tggagcaggt
     3841 atcttggcct gccttctcat ttctatcgta tcttggtact taggaggatt cttccctgtt
     3901 attggcgcgc ccgtttttgc cattttcatg ggaatgctcc tacatccctt tctctcgtcc
     3961 tataaacaac tggatgctgg tttgaccttt agttccaaga agttgctcca atatgccgtt
     4021 gtcttgcttg gttttggtct caatatctcg caggtcttcg cagttgggca atcttcgctc
     4081 cctgtcatcc tgtccactat ctcaatagct ctgattattg cctacttctt ccagcgcttc
     4141 tttgcactgg atacaaaact ggctaccttg gttggagtag gttcttctat ctgtggtggc
     4201 tctgccattg cagcgacagc gcccgttatt gatgctaagg aaaaggaagt agcccaagcc
     4261 atttccgtta tctttttctt caatgtcttg gctgcgctca tctttccaac cctcggcacc
     4321 tggcttcatc tatccaatga aggcttcgcc ctctttgcag ggactgcggt caacgacact
     4381 tcctctgtaa cggctgccgc cagcgcttgg gacagtcttt accaaagcaa taccctcgag
     4441 tctgcaacca ttgttaaact cacacgtact ttggccatta tccctatcac gctctttcta
     4501 tcctactggc aaagtcgcca acaagaaaac aagcaaagcc tacaactgaa aaaagtcttc
     4561 ccacttttta tcctttactt tatccttgcc tctctcctca ctacactact cacctctcta
     4621 ggtgtgtcca gtagtttctt tacccctctc aaagaactct ctaaattcct tattgtcatg
     4681 gccatgagtg ctatcggtct caaaaccaat ctggtcgcta tggtcaaatc cagtggaaaa
     4741 tccattcttc ttggagccat ctgctggata gccatcatcc tcactagtct tggtatacag
     4801 atccttatcg gcattttcta atactaaatt caaaccacgt cagcgtcgcc ttgccgtagg
     4861 tatggttact gacttcgtca gttctatctg caacctcaaa acagtgtttt gagcaacctg
     4921 cggctagttt cctctttgct ctttgatttt cattgagtat aacacaaaag gtagcccacc
     4981 agctaccttt tcttatgctt cctcaatcaa gcgtgtatgt tctctcttga tacaacgatt
     5041 catcacgatg tcatcgcatc caccagcacg caagatttct tccgcctcta gactttcaag
     5101 tcccagctgt gcccaaaaaa tcttggtatc agccttgaga aaatcacgca ccacatctgg
     5161 caaaaactca ctgcgacggt aaacattgac aatatctaca ggaaaaggaa tctctgctag
     5221 gctagcataa gccttttcac ccaatatttc gccacctgcc accttgggat tgactgggat
     5281 gattttataa ccccgagcct gcatttcctt ggtcactcga ttgctggttg tttcctcacg
     5341 gtcagacaag cccaccacag caagggtttt actcattgct agatactgac gaatcacgcc
     5401 atcacttgga ttgataaatt cttgactcat agaaatcctc ctttttcatc agtatagcat
     5461 attttgaaaa ggtttgcaga attctactac aaaaaaggag gactagcccc ctttttattt
     5521 agcctcgtac caggttgccc cttcattctc atctgcgata agaggaacac tgagttgaat
     5581 ggcttcttcc atggtttgtt tcaccaattt tttcatctct accaattcag atttaggcac
     5641 ttcaaggacg atttcatcgt gcacttgtaa cagcatctta gtctgataac cacctgcaac
     5701 caaggcttta tccagctgaa tcatggcaat cttgagaata tctgctgccg aaccctggat
     5761 aggtgagttg atagcagttc gctccgcaaa accacgaata ttgaagttgc gcgaattgat
     5821 atctggcaac tcacggcgac gcttaaagag ggtctctaca tagctcttat cacgcgcctc
     5881 ccgcaccact tcatccatgt agtttttaat acctggaaaa cgttcaaagt aggtatcaat
     5941 gtaggctttg gcttccttac gactaattcc caaattatta gacaagccaa agtctgaaat
     6001 cccataaacc actccaaagt taactgcctt ggcattgcga cggtcgtttg cagtcacatc
     6061 atcaggacgc tcaatgccaa agacccgcat ggctgtcgaa gtatggatat ctgccccctc
     6121 ttggaaggcc ttaatcaagt gctcatcctt agaaatatgc gccaaaacgc gcaattcaat
     6181 ctgtgaatag tcagagctga gtagcacact atcctcccac tctggcacaa aagccttccg
     6241 aatcaagcgc ccctgttcca atcgggcagg aatattttgc aagtttggat ccacactaga
     6301 caaacgcccg gtctgggtca aatcctgcac atagcgagta tgaatctttc catcagccaa
     6361 aatccagtcc tgcaagccaa ttacataagt agattgaatc ttagcaattt gacggtaatc
     6421 caggattttc ttaacaatcg gagcaatagg agcgagacgc tccaacacat ccactgctgt
     6481 cgaataacct gtcttggttt tcttagtgta ttctagagga agtcccaatt tctcaaagag
     6541 aagcacgccc aactgcttag gcgagttgac attaaactcc tcaccagcca gctcgtaaat
     6601 ctcttgagtc agtttttcaa tgacaagctc attttcagcc tgcatctcaa gcaaggtctc
     6661 tttcttgacc ataatcccag caatttccat cttggcaagg acaaaagcca gaggttgctc
     6721 catatcataa agaagctcta attgcccatt ttcgctgagt ttttcaagta aaataggctc
     6781 tgtttctacc aaaacagcaa gtttacaagc taagtgttcc aagaatttct cacgttcagg
     6841 aatggccttt ttaacaccct taccgtagaa agtttcatca tcaaccaagt aagtctgacc
     6901 ataaagacta gcgatggtcg caatttcatt gtcctccaca gtcgaaagga ggtatttagc
     6961 caaacggatg tcaaaagcag gcgcctgcaa atccacacca aaacgttgca aaagaacttt
     7021 aaccttctta aagtcataaa ctctcagaga tgttttttct aagaaatcct tgaaaatcgg
     7081 gtcttgcaac agctcaagct tgtctgtggc atagagctta tcctcacaag accaggcaaa
     7141 tccaaccaaa ttatccgtat ggtaattctc accaaaaagc tcaaagtgga agatagactc
     7201 ttcactcagc atatcttgac tgatttggtc aacaatagta aaatctaaac ccttagccac
     7261 atcagctgac gacacattta aagcctgctt gagctgtttg aagcccatct catcgtaaaa
     7321 tttcccaaga ttttcaacat ctggaccact atagaccaag tcctctaaac caatcgcaat
     7381 cggtgccttg gtatcaatgg tcgctagtgt tttagacaaa aaggcctgtt ccttgtcatt
     7441 gatgagattt tccttcatct tagaagtctt cattccatca atattttcat aaatcccctc
     7501 aagcgaacca tgctccagca agagcttaat acccgtcttt tcaccgactt tggtcacccc
     7561 agggatatta tccgacttat cacccatgag cgccttgaga tcgataaact gagctggtgt
     7621 gaggcccatt tcttccatga ggtaatctgg cgtaaaggcc tcaaactcag ccacaccttt
     7681 cttggaaatt tcaaccaccg tatgctcatc cgtcagctga atcaaatcct tgtccccact
     7741 gacaatggta atatcaaaac catcctgctc tgctagctta tccagcgtcc caatgatgtc
     7801 atccgcctca tactgagcca gctcatagtg acgaatcccc atatgatcca gcaactcacg
     7861 aatgaaagga aattgctcac gaaactcatc aggagtcttg gcccgaccac ccttatagtc
     7921 cgcatacatc tctgtccgga aggtcgtctt tcccgcatca aaagccacca aaatatgact
     7981 cggctcaacc cgctccaaca aatgactcaa catcaactgg aaaccataaa tcgcattggt
     8041 atgcaaacca gccgcattct taaaacggtc caactgctga tacagcgcaa aaaacgcccg
     8101 aaaagctaca gaagacccat caatcaataa taattttttc ttatccatac acccattata
     8161 aaggaaagaa tcaaaaaata ccattgggaa gagctagagc aagtattttt caaacttttt
     8221 ccgaataaat agatagagcc agagaatcta gtaaacctag atttaaaaat gtgctataat
     8281 atagcatatt gaatctataa tagtacatct tgactgctaa aatatttcta taaattaatt
     8341 tgacttttct gatagagttg ttcacatctt atttcaactc actatagaag gaggaaaagg
     8401 aggattctca gacatccgtg catcagccca actaatgatt tgattgctaa gaaaatattc
     8461 agcaatccag aaatcacttg tcaatttatt cgcgatatgc tggacttgcc agcaaaaaat
     8521 gtgaccattt tggagggaag cgatattcac gtattactct ccatgcctta ctcggtgcag
     8581 gatttttata ccagtataga cgtcttggcg gagttggata acggtactca agtaattatt
     8641 gagattcaag tccatcatca gaattttttc atcaatcact tgtggattta cctgtgcagt
     8701 caggttaatc aaaatcttga aaaaattcgt cagcgagaag gtgatactca ctagagctac
     8761 aaacacatcg ctcctgttta cgccattgct atcgtggata gtaattattt ctcagatgac
     8821 ctggcttttc atagctttag tatgcgcgaa gacacaacag gtgaggtatt ggcgattacc
     8881 aacaatggac aggaaaacca tctggttaag atggcattct tggaattaaa aaatacagag
     8941 aaaccagcaa agacaaggtt cgcaagccat ggttggagtt tttcggcaac aagcccttta
     9001 cccagcaacc gcaacgagcc attacccaag caaatcaact gctggactac aagagctggt
     9061 ccgaggagga caggaaaatg tttagtcaac tacatatgcg agaagaacaa gtcttgttag
     9121 cacaggacta tgccttggaa actgctaggg ctgaaggcct tgaacaagga ctagagcgtg
     9181 ggaaagttga aggaagggaa gaaaggaaac tttttgcctt cctagacata gtacgccaag
     9241 gtcttctgac ttctgaggtt gccagccagc aattaggtat gtcagtatct gaatttgagg
     9301 cactgttgta aaa
//
LOCUS       DAVDHC010000057         8576 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVDHC010000057 DAVDHC010000000
VERSION     DAVDHC010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.057"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            153..1172
                     /gene="galE"
                     /locus_tag="VUR43_002125"
     CDS             153..1172
                     /gene="galE"
                     /locus_tag="VUR43_002125"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET5413747.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESSDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            1174..2127
                     /locus_tag="VUR43_002126"
     CDS             1174..2127
                     /locus_tag="VUR43_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5413748.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(2189..2395)
                     /locus_tag="VUR43_002127"
     CDS             complement(2189..2395)
                     /locus_tag="VUR43_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET5413749.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            2447..2923
                     /locus_tag="VUR43_002128"
     CDS             2447..2923
                     /locus_tag="VUR43_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET5413750.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            2932..3603
                     /locus_tag="VUR43_002129"
     CDS             2932..3603
                     /locus_tag="VUR43_002129"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET5413751.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            3734..4072
                     /locus_tag="VUR43_002130"
     CDS             3734..4072
                     /locus_tag="VUR43_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET5413752.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            4075..4704
                     /locus_tag="VUR43_002131"
     CDS             4075..4704
                     /locus_tag="VUR43_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET5413753.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            4944..6095
                     /locus_tag="VUR43_002132"
     CDS             4944..6095
                     /locus_tag="VUR43_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET5413754.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFNILGGWLIVISIFVMYLLQKRA"
     gene            6408..7157
                     /gene="truA"
                     /locus_tag="VUR43_002133"
     CDS             6408..7157
                     /gene="truA"
                     /locus_tag="VUR43_002133"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET5413755.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            7147..7920
                     /locus_tag="VUR43_002134"
     CDS             7147..7920
                     /locus_tag="VUR43_002134"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET5413756.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     WIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            7898..8359
                     /locus_tag="VUR43_002135"
     CDS             7898..8359
                     /locus_tag="VUR43_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET5413757.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         2411 a         1609 c         1925 g         2631 t
ORIGIN      
        1 atggcaaggc gacgttgacg tagtttgaat tggattttcg aagagtataa gcattttact
       61 gaaattttat caggtagttt aggatggcaa atgacattcc ctgtcaaaaa tggtaaaata
      121 agaaaaaata atctgagaat cgaggaaaaa agatgcaaga aaagattttg gtaactggtg
      181 gtgccggttt tattggaacc cacactgtta ttgaattgat ccaagcaggc catcaagttg
      241 ttgtggtgga taatcttgtc aatagcaatc gtaagagttt agaagttgtt gaaagaatca
      301 caggagttga gattcctttc tatgaggcag atattcgtga cacagatacc ctcagagata
      361 ttttcaagca ggaagaaccg actggtgtca ttcactttgc tggtttgaag gctgttggcg
      421 aatcaacacg tatccctctt gcctactatg acaacaatat cgctggaact gtcagccttt
      481 tgaaagcaat ggaagaaaac aactgtaaaa acatcatctt cagttcttct gcgacagttt
      541 acggggatcc gcacacagtg cccatcttgg aagatttccc actttcagtg accaacccat
      601 acggtcgtac taagctcatg ctagaggaaa ttttgactga tatttacaaa gcagactcag
      661 aatggaatgt tgtcttgctt cgttacttta acccaatcgg agcccatgag agtagtgatt
      721 tgggagaaaa tccaaacggt attccaaaca atctcttgcc atatgtgact caagtagccg
      781 ttggaaaatt agagcaagtg caagtgtttg gagacgatta cgatacggaa gatggaacag
      841 gtgttcgtga ctatatccac gttgtcgatt tggctaaggg tcacgttgca gctttgaaaa
      901 aaatccaaaa aggttcagga ctaaacgttt ataaccttgg aactggtaaa ggttactcag
      961 ttcttgaaat tatccaaaac atggaaaaag cggtgggacg tcctattcct taccgcatcg
     1021 tagaacgtcg cccaggtgat atcgctgcct gctactcaga cccagcaaaa gctaaagcag
     1081 aactcggttg ggaagcagaa ctcgacatca cccaaatgtg tgaagacgca tggcgttggc
     1141 agagcaagca tccaaatgga tttgaagact aagatgatga tttcaatcat cgtcccttgt
     1201 ttaaacgaag aggaagtact tcctcttttt tatcaggctc tggaagcttt acttccagat
     1261 ttggaaacag aaatcgagta tgtctttgtc gatgatggat caagtgatgg gaccttggaa
     1321 ctcttaaagg cctatcggga gcaaaatccg gcagtccatt atatttcttt ctctcgaaat
     1381 tttggcaaag aagcagccct ttatgcaggc ttgcaatatg cgacaggaga tttggtggtg
     1441 gtgatggatg cagacctcca agatcctcct agtatgttgt ttgagatgaa aaatgtacta
     1501 gacaaaaatg tagacttgga ctgcgttggg acacggagaa ctagtcggga gggagaaccc
     1561 ttctttcgca gtttctgtgc tgttctcttt tatcgcctca tgcaaaaaat cagcccagta
     1621 gctctgccgt cgggtgtccg tgactttcgt atgatgagaa ggtctgtggt cgatgccatt
     1681 ttaagcttga ctgagtccaa tcgtttttct aagggactct ttgcttgggt cggctttaaa
     1741 acccactatc tggactatcc aaatgtcgaa aggcaggctg gcaagaccag ttggagtttt
     1801 aggcaactct ttttttactc cattgaaggg attgttaatt tttcagattt ccctttgact
     1861 atagcctttg tagctggtct cctatcttgt tttctttctc tgctgatgac cttttttgtt
     1921 gtggttcgaa ccctcatttt gggcaatccg acatctggtt ggacctctct gatggctgtt
     1981 attctctttc ttggaggcat tcaactcttg accattggga ttctcggcaa gtatatcagt
     2041 aagatttatt tagagactaa aaaaagacca ctttatctta tcaaagaaaa aagtgacctt
     2101 cctgatttta cagaaaaaat aaagtgaaaa gactataatt ttacatggaa atgtgctaaa
     2161 ctagagggag tggattatcg ccattgattt aggcttcctg gtttccaatc agggcgcgag
     2221 ttgggcaatt tttaacagcc tctaagacat cctgactagg agaaatttct ttttccagtt
     2281 ggtcagggtc atcgtaaaaa cgcacgattc cattatcgtg gtaatcaaat aaatcagaat
     2341 aagtttggca aagtccacag gcgatacatc gttcaggtat aagtgtgatt ttcatgttca
     2401 tatttatatt gtaataagaa aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc
     2461 gtggcaagaa gatatttatg atcaagaaga atcaagagca gggcgtcggc atcgaaacca
     2521 cggaggggct gataggatgg ctaatcgtat tttgacgatc ctagctagta ttttctttgt
     2581 aattgtggtg gtgatggtca tcgttctcat ctatctatca tcggggggga gcaatcgcac
     2641 agcagcctta aaagactttc atgattctga tgcaagtgta gtacaaatct catcttcaag
     2701 cagttctcag cctgagcaga gttcagagcc agaatctact tctagtagtt cagaagaagc
     2761 tgctaatcct gaaggaacga ttaaagttct cgcaggagaa ggggaagcag ctattgccgc
     2821 tcgtgcagga atctctattg ctcagttaga ggccttgaat cctgggcaca tggctacagg
     2881 atcttggttt gctaatccag gtgatgttat aaaaataaaa taggagccga tatgaaaaca
     2941 attcaaattg ctattgatgg tcctgcttcc agcggtaaga gtacggtcgc aaagattatt
     3001 gctaaggatt ttggattcac ctaccttgat acaggagcta tgtatcgtgc agcgacctat
     3061 atggctctta agaaccaatt aggagttgaa gaagtcgaag cccttctagc cttgttggac
     3121 cagcatccaa tcagctttgg acgttcagaa actggagacc agcttgtttt tgtaggagat
     3181 gtggatatta cccatcctat ccgtgaaaat gaagtgacca atcatgtttc tgctattgca
     3241 gcaattcctg aagtgcgtga gaaactggtt tctctccaac aagaaattgc ccagcaaggc
     3301 gggattgtca tggatggtcg cgatattgga actgttgtat tgccacaagc agaattgaaa
     3361 attttcctag tagcttctgt tgatgagaga gcagagcgtc gttacaagga aaatattgcc
     3421 aagggaattg aaacagacct tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag
     3481 gatagtcatc gtgagacttc tcctctcaaa caagcagagg atgctgtcta ccttgataca
     3541 actggtttga acattcaaga agtagttgaa aaaatcaaag cagaagctga aaaaagaatg
     3601 taaatgtaga aaagccgata gattgatatc ggtttttttc taaatttgtc aaaatgctga
     3661 ttttagggta taatagttgc tgttcgagaa attttgattt tcaaagaata gtgaatgatg
     3721 ataaggagaa accatgaaca atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta
     3781 cgaagacggt gccctactgg tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt
     3841 tgcagaagta gaagaaggtc ttgtcgctat cgatgccaac ggaaataaat tgactgatgg
     3901 tgatacagta actctcatca aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca
     3961 agggacgcgc gtgaaaaata tccgcatcgt agaaggcgat cacaatatcg actgtaagat
     4021 tgatggtttt ggtgccatga aacttaaatc agagtttgtg aggaagattt aagcatgtca
     4081 aaacactata aacttgtatt ttatagccgt atcttcttgt ttctagcggc ttttacggga
     4141 gtttatcttg aaattactag gcatggtggt tttgggatgc ttctctatta cacggttctg
     4201 tccaacctct tggtaactat ttttaccctt tatcttctaa aggttatgag ccgtgtaggt
     4261 gaaaattggc aaaggccaag tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg
     4321 attacctgtg tgatttacca tttcctcttg gcgcccattg cgactaattt ctatacccta
     4381 gaaaatttcc tttgccacta tatcgttccc atctggtttt tagcggatac cctctttttt
     4441 gacaaacagg gtcaatacaa gatttgggat ccagcagtgt ggaccatttt accctttctg
     4501 tatatgatgt ttgctctttt taatggcttg gttctaaaac tcaatattcc aaatgccaag
     4561 gataatcctt tcccttactt ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag
     4621 tggtgtctga ttatctttgt tgcctatatg gtagcaggat ttattttcta ctttatcaag
     4681 caaatcaaga gaaagtcatc ctaatactct tcgaaaatct cttcaaacca cgtcagtttc
     4741 catctgcaac ctcaaaacac tgttttgaac aacctgcggc tagctttcta gtttgctctt
     4801 tgattttcat tgagtatgag atacaaggga ttcattttcg aatttaagaa ggagtctaca
     4861 aaccaatgag gcttcttctt ttcttgctta tttgataact atcaaaaaag tagaagatta
     4921 agagaaatat agaaagagat ttcatgaaac aatttttaga acgggccagc attttggctc
     4981 tctccctcgt tttgattacc tccttttcca tttcgagtgc cctaccagcc atgtttgact
     5041 attatcaggg ttattctaag gaacaaattg agctcttggt gagcttgcct tcctttggaa
     5101 tcatgatgat gttactgcta aatggtttct tagaaaaaat atttcctgag cgcttacaga
     5161 ttagtttggg cttgctgatt ttatcattga gcggtacagc tcccttctgg taccaagcct
     5221 atccctttgt ctttggaaca cggcttctct ttggtttggg tcttgggatg atcaatgcca
     5281 aggccatttc tattatcagt gaacgctacc aaggaaaaag gcgaattcag atgttagggc
     5341 tacgcgcttc tgcagaggtc gttggagctt ctctcattac cttggccgtc ggtcagttgt
     5401 tggcctttgg ttggacagct atctttctag cctatagtgc tggatttttg gtgctgcccc
     5461 tttatctgct ctttgtccct tatggaaaat caaagaaaga agtcaagaaa agagcgaagg
     5521 aagcaagtcg tttaactcga gaaatgaaag gcttaatttt taccttagct atcgaagcgg
     5581 cagttgtagt ttgtaccaat acagctatta ccatccgtat tccaagtttg atggtggaaa
     5641 gaggattggg ggatgcccag ttatctagtt ttgttcttag tatcatgcag ttgatcggga
     5701 ttgtggctgg ggtgagtttt tctttcttga tttctatctt taaagagaaa ctgctcctct
     5761 ggtctggtat tacctttggc ttggggcaaa tcgtgattgc cttgtcttca tccttgtggg
     5821 tggtagtagc aggaagtgtt ctggctggat ttgcctatag tgtagtcttg acgacggtct
     5881 ttcaacttgt ctctgaacga attccagcta aactcctcaa tcaagcaact tcatttgctg
     5941 tattaggctg tagtttcgga gcctttacga ccccatttgt tctaggtgca attggcttac
     6001 taactcacaa tgggatgttg gtctttaata tcttaggagg ttggttgatt gtaatctcta
     6061 tctttgtcat gtacctactt cagaagagag cttaggattg attcctaagt ttttcttttg
     6121 atactcaatg aaaatcaaag agcatagttg attgagtttg gaatagtacg ctgtagctgc
     6181 taaaatattt ctagaaatta atttgacttt tctaatagag ttattcatat cttatttcaa
     6241 tctactatag aaagctagcc gcaggttgct caaaatagtg ttttgaggtt gcagatggaa
     6301 actgacgtgg tttgaagaga ttttcgaaga gtatgagatt tttataccca tacaatattt
     6361 gttttaggtc cttgtttaca gactaatttc ttgataaaat agaggttatg acgagatata
     6421 aagcaactat ttcctatgat ggttatgcct ttgctggctt tcagcgccag tctcatgcgc
     6481 gtagcgttca ggaagaaatt gaaaaaacct tgaccagatt aaataaaggg caaaccatta
     6541 ctgttcacgg tgctggtagg acagatagtg gggttcatgc cctgggacag gtcattcatt
     6601 ttgacctgcc ttatcagatg gatgaggaga aactccgttt tgccttggat acccagtctc
     6661 ctgaagatat tgatgtgatt tcgattgagc ttgtggcaga tgattttcat tgccgttatg
     6721 ccaaacatag caagacctat gagtttattg tggatagagg acgtcccaaa aatcctatgc
     6781 gccgtcacta tgccacccac tttccctacc cactcgatgt ggaacgaatg cagattgcaa
     6841 tcaaaaagct agagggaacc catgatttta ccggttttac agcctctggg actagtgtag
     6901 aggataaggt tcgcaccatc acagaagcta gtttaatagt cgatgagaca ggacaatttt
     6961 tgacctttac cttttcagga aatggtttct tgtataaaca gattcgcaat atggtgggga
     7021 ctcttctcaa aatcggtaac aaccgcatgc cagtagagca gattgatctc atcttggaga
     7081 agaaggacag gcaacttgca ggtcccactg cagcaccaaa tggtttgtat ttaaaggaga
     7141 ttcgttatga agaataatcg tattttagca ctttctggaa atgatatttt tagtggtggt
     7201 ggactgtcag ctgatttggc tacctatacc ttgaacggct tgcatgggtt tgtagcagtg
     7261 acttgtttga cagccttgac agaaaaagga tttgaagtct ttccaactga tgataccatt
     7321 tttcaacatg aattagatag cttgcgtgat gtggaatttg ggggaattaa gattggtctt
     7381 ctccctactg tcagtgtggc tgagaaggcc ttggacttta tcaaacaacg cccaggagta
     7441 cctgtggtgt tggatcctgt cttggtctgc aaggaaacgc atgatgtagc tgtcagtgag
     7501 ctctgccaag agttgattcg ctttttccct tatgtcagtg tgattacgcc taatctccca
     7561 gaagcagaat tattatccgg tcaggaaatt aaaaccttgg aagacatgaa aactgcagcg
     7621 cagaaattgc atgatttagg agcgccagca gtcattatca agggaggcaa tcgtcttagt
     7681 caggacaagg ctgtggatgt cttttatgat ggacagacct ttactatcct agaaaatcca
     7741 gttatccaag gccaaaatgc tggtgcaggt tgtacctttg cctctagcat tgccagtcac
     7801 tggattaaag gtgataaact tttgccagca gtagaaagct ctaaggcttt cgtttatcgt
     7861 gctattgcac aagcagatca gtatggagta agacaatatg aagcaaacaa aaacaactaa
     7921 aatcgccctt gtatccctat taaccgccct ttctgtggtt ctaggttatt tcttaaaaat
     7981 cccaacacct acaggaattc taactctttt agatgctggt gtcttctttg cggcctttta
     8041 ctttggtagt cgtgaaggag cggtagtcgg aggactagca agtttcttgc ttgacctctt
     8101 atcaggctac cctcagtgga tgttctttag cttggtcaac catggcttgc agggattttt
     8161 cgcaggattt aaaggaaaaa gtcagtggtt aggccttatt ttagcaacta ttgccatggt
     8221 agggggctac gccttgggtt ctactttgat gaatggctgg gcagcagccc tcccagaaat
     8281 tctaccaaat tttatgcaaa atatggtagg gatgattgta ggatttattc ttagtcaaag
     8341 tatcaagaag attaagtaat actcttcgaa aatctcttca aaccacgtca gcttgtcctt
     8401 agtgtgtata tgttactgac ttggtcagtt ctatccttaa cctcaaaact atgtttcgag
     8461 gagccttccg ctaacttccc agtctgagtt tcattgaata ttaacgatac tttatcacat
     8521 aaagaggctg gatgaaaagt cttcacaatc aaaaaaacgc atcatatcag gtgtac
//
LOCUS       DAVDHC010000058         7633 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVDHC010000058 DAVDHC010000000
VERSION     DAVDHC010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7633
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.058"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(284..508)
                     /locus_tag="VUR43_002136"
     CDS             complement(284..508)
                     /locus_tag="VUR43_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015990842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413758.1"
                     /translation="MSKLSRKPNHHVKKLTWSDLDNILISAFTESATDHPSAVIRLSD
                     YEMSKSEIIEEAIAQGYTVIDNSDDFLEFE"
     gene            626..769
                     /locus_tag="VUR43_002137"
     CDS             626..769
                     /locus_tag="VUR43_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413759.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     KTV"
     gene            836..1633
                     /locus_tag="VUR43_002138"
     CDS             836..1633
                     /locus_tag="VUR43_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HET5413760.1"
                     /translation="MNMNLNTNEILTTTEYDMFRKISNRKITENPKLEEELLSEGQRQ
                     PILVNEKMEVIDGQHRLYYLRKHRKPVRYIIDPTANFKTVISMNTSAVNWALQDYVYS
                     FALEGDPEFVKLAKFLDENELLSDKMVIVAGSGRRDGTATHVVKKLKKGDYVFSNEKQ
                     LREFCKFYERVLNETKLPNKPFLQSVLWTLYTTSVFDENRMLTQLKKSDLTSEDIEGF
                     AKKKLLLTFLELYNGRWSDDHPSLIQYFINRKGSLTIPSLPKQDEDN"
     gene            1651..1788
                     /locus_tag="VUR43_002139"
     CDS             1651..1788
                     /locus_tag="VUR43_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413761.1"
                     /translation="MKVTVYAYGRKLEPDELIIIPENHRFYDIWNGIVNEMLDNEEDV
                     A"
     gene            1788..2009
                     /locus_tag="VUR43_002140"
     CDS             1788..2009
                     /locus_tag="VUR43_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413762.1"
                     /translation="MKLLTKLKLRLEGVLKSVNLDWREVAIEVSNDLLEERKRRFMRE
                     QENHDLKQELAAYKYKENFDIKARLQGEM"
     gene            2010..2264
                     /locus_tag="VUR43_002141"
     CDS             2010..2264
                     /locus_tag="VUR43_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413763.1"
                     /translation="MYIISIYVKNTETGNEDFSLIGRDFLPTGHQDYIARVFGTKEEA
                     IDYLKSISYIASGVHGNDWVYQNEKLPEIESRCRIWKVGE"
     gene            2277..2531
                     /locus_tag="VUR43_002142"
     CDS             2277..2531
                     /locus_tag="VUR43_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413764.1"
                     /translation="MFKALKTIKKIKQLQKEMHAFSLAFLALQDMSLMSETERSKAKA
                     QTMHDVSHMLKDVLGGKSVDEAMKRLNSEVKIEDVEQEDD"
     gene            2762..3580
                     /gene="bet"
                     /locus_tag="VUR43_002143"
     CDS             2762..3580
                     /gene="bet"
                     /locus_tag="VUR43_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HET5413765.1"
                     /translation="MTNNQIVEAKGDFLTNPQLLNSGIIRKYLDPQGKASDEELAYFI
                     AQAKAQNLNPFTKEIYFIKYGTQPAQIVTAKSAFEKKADSHPQFDGKEAGVIYLMDGE
                     IKYSKGAFIPKGAEILGGWAKVYRKDRTYPTETEVSFEEYDNSKIRARVKELTQQGKD
                     VTYPVMNSYGKPIGENNWDTMPCVMIRKVALVSAYREAFPAELGASYEADEIQLDNTP
                     KDVTPQESREDVVARKMAQIEQFNKGQEANHADPEPAQTEETIQGELLDGELEY"
     gene            3590..4630
                     /locus_tag="VUR43_002144"
     CDS             3590..4630
                     /locus_tag="VUR43_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HET5413766.1"
                     /translation="MQELQVKVTQAQVEIIDREKFEQNINEVVAKYQNYTVTAATIKD
                     DKQTLADLRKLDKQVSDERIRNKKVLSEPADEFDKYVKNAIQPLKDIITKIAGDVKEF
                     EEHQKAVRIDTVKGYLANKSAEYMLDPRLFDEKALEYVKASDFMADGVTLKKATMKSL
                     DDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEVFGQIKADYEFE
                     KQKEEIRQAQERAERESQELLAAQQTKQQEQAPKSTETPNFDPETGKILDGGQILQNE
                     PNALRGAENDLKRYAQKMTLEVYFVDTAEKDCFKAGLSQLGFDFKKNYQVRGYQRIEP
                     LTQAELNEQCGW"
     gene            4633..4794
                     /locus_tag="VUR43_002145"
     CDS             4633..4794
                     /locus_tag="VUR43_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413767.1"
                     /translation="MTEIEKISEELAEYGVPDELIGKIEDLLATLYGEKKEIGDRKIL
                     DISPESMGR"
     gene            4797..5120
                     /locus_tag="VUR43_002146"
     CDS             4797..5120
                     /locus_tag="VUR43_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413768.1"
                     /translation="MDIRKISDSVAIYSDGKKLQVIHNLGDEFILDFNVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEIFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            5113..5448
                     /locus_tag="VUR43_002147"
     CDS             5113..5448
                     /locus_tag="VUR43_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HET5413769.1"
                     /translation="MIKTVFFSCDYPHHEAIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            5543..5959
                     /gene="ssb"
                     /locus_tag="VUR43_002148"
     CDS             5543..5959
                     /gene="ssb"
                     /locus_tag="VUR43_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET5413770.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFQAWRGTADIIAQYCSKGSLIGLTGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            5969..6475
                     /locus_tag="VUR43_002149"
     CDS             5969..6475
                     /locus_tag="VUR43_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET5413771.1"
                     /translation="MSKIKILDACCGSRMFWFDKNESHTIFMDIRQETFEIHDKKVNV
                     DPDIIGDFRDMSFEDNTFNLVVFDPPHLKWAGPNSIMKAQYGQLDKVTWSEDLAKGFE
                     ECLRVLKVGGTLVFKWSDRQINVKKLLEVIPFKPLFGQQRGTTHWLTFVKFEEDKNGV
                     DGLGGLET"
     gene            6441..6650
                     /locus_tag="VUR43_002150"
     CDS             6441..6650
                     /locus_tag="VUR43_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413772.1"
                     /translation="MEWTDWVDWKPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     MDIKQDCLRLGVPFEDMYPLQTTLF"
     gene            6664..6993
                     /locus_tag="VUR43_002151"
     CDS             6664..6993
                     /locus_tag="VUR43_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413773.1"
                     /translation="MASKINVTERIAIIIEKQKIEVVTTLNCDMSISFDNKDTAPTLD
                     DNGDLFEPVYKCKVKAIPKNDVFFTSLIRVKSNIKTLQEVKKFFEFVNENRENLFEMA
                     GFKGALE"
     gene            6990..7421
                     /locus_tag="VUR43_002152"
     CDS             6990..7421
                     /locus_tag="VUR43_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HET5413774.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRARLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEIEVMKSLSI"
     gene            7437..7619
                     /locus_tag="VUR43_002153"
     CDS             7437..7619
                     /locus_tag="VUR43_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413775.1"
                     /translation="MADYALYQGDVFVTLGTLAQISSETGITERMLKYYTYTSHQRRH
                     PNGRAVIKIEEEDNEN"
BASE COUNT         2708 a         1325 c         1664 g         1936 t
ORIGIN      
        1 tctaataagt actaactata caacaagtac taactataca ataatctaag cctaacggca
       61 ctaacttagt aataactact aacttacaac aaactaatac ttctctaaaa aataaaagag
      121 agaaatttca attttaggac tttgaaaaat aggaaaggag aaaaaatgag accaagacga
      181 tatccgtatt caggaagaaa gaaaaggcaa tccgatgaac agattgctaa attaaaaaga
      241 tatgttgaag caaatagtac taacatatca tatttgaccc acgctattca aactctaaga
      301 agtcatcaga attgtcaata actgtgtaac cttgtgcaat tgcttcttcg ataatttcgg
      361 atttagacat ctcataatca gataatcgga ttactgcact aggatgatca gtcgctgact
      421 ctgtaaaagc agatatcaga atgttatcaa ggtctgacca agtaagtttt ttaacatggt
      481 ggtttggttt tctgctaagt ttactcatat aattttcctc ctttctattg aaattttgac
      541 taaaacagtg agaggtccta gtcaagagta ttatagcaat ttaggaggat attacatcag
      601 tcttgaggct gatataggag gttgaatgga agataaaatt atcgaacttg ctgactactt
      661 catcagcgaa tctacaacgt acagagaagc taaaatagcg tgtgagaagc tattgaaaca
      721 agtcagccat gagatagaac tcagggcaat ggaaagtaag acagtctaga agacaacaaa
      781 aagcacctga cggcaatcag gcgcatacta aaaaacttta caagaggatt ataacatgaa
      841 tatgaactta aatacaaatg aaattttaac aactactgaa tatgatatgt ttcgcaaaat
      901 tagtaataga aaaataactg aaaatcctaa attggaagag gagctacttt ctgagggaca
      961 acgtcagccg attttggtaa atgaaaaaat ggaagttatc gacgggcaac atcgtcttta
     1021 ttacttgaga aaacatagaa aaccagtgcg ctacataatt gatccgaccg ctaatttcaa
     1081 gacagtaatt tcgatgaata catcagctgt caactgggca ttacaagatt atgtgtattc
     1141 gttcgcttta gagggagatc ctgaatttgt taaattagct aaatttttag acgagaacga
     1201 attgcttagt gacaagatgg taatcgtagc tggttcagga agacgtgatg gtacggcaac
     1261 acacgtagtc aaaaaattaa aaaaaggcga ttatgtattt tcaaacgaaa aacagttaag
     1321 agaattttgt aagttctacg aacgcgtttt aaacgaaaca aaactgccta acaaaccatt
     1381 tttacaatct gttttatgga ctttgtatac aacatcagtt tttgatgaaa acagaatgtt
     1441 gacacaattg aagaaatcag atttgacatc agaagatatc gaaggatttg caaagaaaaa
     1501 attgctatta acttttttag agctatacaa cggaagatgg agtgacgatc atccttcttt
     1561 aattcaatac tttatcaaca gaaaagggtc gttaacaatt cctagtttgc ctaaacaaga
     1621 tgaagataat taaaaaagta ggaagataaa atgaaagtca cagtatatgc ttacggccga
     1681 aaattagaac cagatgaact aattatcatc ccagaaaatc atcgttttta tgacatttgg
     1741 aacggaattg taaatgaaat gctcgacaac gaggaggatg tagcttaatg aaactactta
     1801 ctaaattaaa actcagactt gaaggagttc ttaaatcagt caaccttgac tggagagagg
     1861 ttgctattga ggttagcaat gaccttctcg aagagcgcaa acgtcgcttt atgcgtgagc
     1921 aagaaaacca tgacttgaag caggagcttg ctgcctacaa gtacaaagaa aactttgata
     1981 tcaaggctag actgcaagga gaaatgtaga tgtacattat atcgatttat gtcaagaata
     2041 ctgaaactgg aaacgaggat ttcagtttga ttggacgtga tttcttaccg acggggcacc
     2101 aagactatat tgcaagagtt tttggaacaa aagaagaagc gattgattac ttaaaatcta
     2161 tatcttacat cgcatcaggt gttcatggta acgattgggt ttatcaaaat gaaaaactac
     2221 cagaaattga gtcacgttgc cgaatttgga aagtaggaga ataaaaggag aacaatatgt
     2281 ttaaagcact aaaaacaatc aaaaaaatca aacagcttca gaaagaaatg cacgctttca
     2341 gccttgcgtt tctagctcta caagatatga gcttgatgtc agagactgaa agaagcaagg
     2401 cgaaggctca aacaatgcac gatgtaagcc acatgctcaa ggacgtcctg ggcggcaagt
     2461 cggtagatga agccatgaaa cgtctaaata gcgaagtgaa aattgaagat gtggagcagg
     2521 aagatgacta gaattgaact tgaaaaccgt gtatggcttt tggctaatca tgaagaaaaa
     2581 aacgaattgc tggatcttgg aaaggtgtat gctcatgttt gattacgaca gagacataat
     2641 gcagcctcct gaacccagag aagaacatga cccagctgat tggattttca gcgctggtca
     2701 atggatctat gtaggagatt gttagcctat gaatagagaa cacaacgaaa ggtagaagga
     2761 aatgacgaat aatcaaattg tagaagcaaa aggcgacttt ttaaccaacc cacagctact
     2821 taatagcggt attatcagaa agtatcttga cccacaagga aaagctagtg atgaggagct
     2881 tgcctatttt atagctcaag ccaaagccca aaacctcaat ccatttacaa aagaaattta
     2941 ttttatcaag tatggaactc agccagccca gatagtcact gccaaatcag cttttgaaaa
     3001 gaaagcagat agtcacccgc aatttgatgg caaagaggca ggcgtaatct atctgatgga
     3061 tggtgaaatt aaatactcaa aaggagcatt tattcctaaa ggtgctgaaa ttcttggcgg
     3121 ctgggctaag gtgtaccgca aagaccgtac ttacccaacg gaaacagaag tatcttttga
     3181 ggagtacgac aattctaaaa tacgtgcaag agttaaggaa ctgacacaac aaggtaaaga
     3241 tgttacttat ccagtgatga actcatacgg taagccaata ggtgagaata actgggatac
     3301 tatgccttgt gtcatgatac gaaaagtagc tctagtgtca gcttaccgtg aggcgtttcc
     3361 tgccgagctt ggagcaagct atgaggctga cgaaattcag ctggataaca cacctaaaga
     3421 cgtcactcct caagaaagcc gtgaggatgt cgtagcacgc aagatggctc agattgagca
     3481 attcaacaaa gggcaagagg caaatcatgc agatcctgaa cctgctcaaa ctgaggaaac
     3541 aatccagggc gaattgctag acggtgaact tgaatattag gaggacaaca tgcaagaatt
     3601 acaggtaaaa gtaacacaag cacaggttga aatcattgac cgtgagaaat ttgagcagaa
     3661 tatcaatgag gttgtagcaa agtatcaaaa ttacacggtt acggctgcaa ctatcaagga
     3721 tgacaagcag acacttgccg atctacgaaa attagacaag caggtttctg atgaacggat
     3781 caggaataag aaagtcttat ctgaaccagc tgatgaattt gacaagtatg tcaagaatgc
     3841 catccagcct ctaaaagaca tcattaccaa aattgctggt gatgtcaaag agtttgaaga
     3901 acatcaaaag gctgtccgaa ttgacacagt caaaggctac ctagccaaca aatcagctga
     3961 gtacatgctg gatcctcgtc tctttgatga aaaggccctt gagtatgtca aagctagcga
     4021 ttttatggca gatggcgtga cgcttaaaaa agccactatg aagtcacttg atgacatggt
     4081 cacatttgaa tttcagaaac aacaagaatt tgaaaaagcc aagtcagcta tttcagggtt
     4141 atgtgctgag tatggcatga ctgactcacc ttacattaga cagctgaaag acttgactct
     4201 tgctgaagtc tttggacaaa tcaaagctga ttatgagttt gaaaagcaaa aggaagaaat
     4261 cagacaggct caagaacgag cagagcgaga aagtcaggaa cttttagcag cccaacaaac
     4321 caaacagcaa gaacaggctc caaaatcaac ggaaacccca aattttgacc cagaaacggg
     4381 caaaatcttg gacggtggac aaatcctcca aaatgagcct aacgctctta gaggggctga
     4441 aaatgaccta aaacgatatg cccaaaaaat gactttagag gtgtattttg tagacacagc
     4501 cgaaaaagac tgtttcaagg ctggtctaag tcaactcgga tttgatttta aaaagaacta
     4561 tcaagtcagg ggttatcaac gtatcgagcc attaactcag gctgaactaa atgaacaatg
     4621 tgggtggtaa gtatgacaga aattgaaaaa atttcagaag aattggctga atatggggtg
     4681 cctgatgagt taataggaaa aatagaggac ctattagcga ctctgtatgg cgaaaaaaag
     4741 gaaattggag atagaaaaat cttggatatt tctccagagt caatggggag gtaaccatgg
     4801 acatcagaaa aatatctgac agcgtagcca tctactcgga cggcaagaaa ttgcaggtta
     4861 tccacaacct aggggatgag tttatccttg atttcaatgt gggagaggat agcgtctgga
     4921 acctcaatgg ccaagtcgta gaaattattg acatgattga gcctgtcttt aaagttttca
     4981 gcttttgctc aaaatctgga gagggtatgc aacgcttaaa acatgctatc gtccactttg
     5041 aaatatttga gcagtacatc agagataatc aggaagacct gatgatctgg tggcacaatc
     5101 caggagggga atatgattaa aaccgtattt ttttcatgtg attatccaca tcatgaggcg
     5161 attgacgacc aaataaatag ctggcttgcc gaaaatccag gcattaagtt gattgacatc
     5221 aaatttcaat caaatgtgtc tgctgtcgct gacagtggag tcagtgctga atattggcat
     5281 acatccgcat tgattattta caaagttccc tcagagaaca atataagcag tattaattca
     5341 aatggtttag gtttcataat cagctgtgag aaatgtggta gcttatcaat aatcaaggga
     5401 aaagatgtag gtcaaaatgt atgttatgaa tgcaaaggag agaaataatg aatgatttta
     5461 tcaaagagat tgggatggct atcctatgga tgtttttagg gtatctcttg ggagagcgta
     5521 gcactagagg gggacaaatc agatgatcaa taacgtcaca ctggttggga ggcttgtagc
     5581 gcctcctgat ctacgaaaaa cgcctaataa tgtatctagt ttacagggca cgcttgcagt
     5641 caatcgcaat ttcaaaaacg aaaatggaga gcgtgaggct gattttatca attttcaagc
     5701 ttggagaggt acagctgaca tcattgctca gtattgcagc aagggctcac ttattggcct
     5761 cacagggcgc ttacaagtta ggtcttacga gaaagacggt cagcgtcgat atgtgactga
     5821 agtaatcgct gagagtgtag ctctgctaga gagtcgcaac agtcagcacg gacaaggcaa
     5881 cagtttccaa aatgggaata gctcaccttt taccgatcct aacccctttg acctcccaaa
     5941 tgacggtttg ccgttttagg aggtatatat gtcaaaaatt aaaattcttg acgcttgctg
     6001 tggcagtcgt atgttttggt ttgataaaaa cgaaagtcac acaattttta tggacattag
     6061 gcaagaaaca tttgagatac atgacaaaaa ggtcaatgta gaccctgata ttatcggtga
     6121 ttttcgtgac atgtcttttg aagacaacac atttaatcta gttgtgtttg atccaccaca
     6181 tctaaaatgg gctggaccta attcgataat gaaagctcag tatggacaac tggacaaagt
     6241 tacctggtcg gaagatttgg ccaagggttt tgaagaatgt ctgagagttc taaaagttgg
     6301 cggcacacta gtctttaaat ggtctgaccg tcagataaat gtaaagaaat tactagaggt
     6361 gataccattc aagcccttat ttggtcagca aagaggcacc acacactggc taacgtttgt
     6421 aaagtttgag gaggacaaga atggagtgga cggattgggt ggattggaaa cctgaaacca
     6481 aaacggacat taaaaccaaa attgaaaatg acgggtacac ttttccacat tacgacaaga
     6541 aaaacaatgg cgtcaagtat gtgatttcta caatggacat caaacaagac tgtctaagac
     6601 ttggagtacc gtttgaagat atgtaccctt tgcaaacgac acttttttaa caggagaaag
     6661 aacatggcaa gtaaaatcaa tgtgacagaa cgtattgcta tcatcattga gaaacaaaaa
     6721 atagaggtcg ttacgactct aaactgtgat atgagcatta gctttgataa caaagacacg
     6781 gctcctacac tagatgacaa tggtgacctt tttgaaccag tctacaagtg caaagttaag
     6841 gcaattccca aaaatgatgt atttttcacc tcattaatac gggtcaagag caatatcaag
     6901 acgttacaag aggttaaaaa attctttgag ttcgtaaacg aaaacagaga aaatctcttt
     6961 gagatggcag gatttaaggg ggctcttgaa tgaaattgac cctgaacatt gagcctaaac
     7021 ctcaatcacg gccaaggttt gcaagacgtg ggagttttac cacaacttac gaagacaagg
     7081 atatgaaaac atggcgcaat cattgccagc tgctcattgc taatcagtac atgggtcagc
     7141 ctatccttga gggagctttg agggcacggc ttagatttta tatcaaacct cctcagtaca
     7201 tttctaaagt caagaagaac caacaggccc tcctggatga aattatacca gtaggcaaaa
     7261 agcctgacat agataactac gaaaaagcgc tatatgatag catgtcaggg atcgtcttcc
     7321 aggacgacgg tcagatagcg ctacatgatg taggcaagtt ctacagtcta aatccacgga
     7381 tagaggttga gattgaggtc atgaaatccc tgagtatttg aagaaatgag gagcagatgg
     7441 ctgactacgc attatatcaa ggtgatgtgt ttgttacgct tggaacatta gcgcagatca
     7501 gtagcgagac aggaattact gaaaggatgt taaagtatta cacttacaca tcacaccaaa
     7561 gacgacaccc aaacggtagg gccgttatta aaattgagga ggaagataat gagaattaag
     7621 acggaaagtg aag
//
LOCUS       DAVDHC010000059         7580 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVDHC010000059 DAVDHC010000000
VERSION     DAVDHC010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7580
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.059"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(122..1972)
                     /locus_tag="VUR43_002154"
     CDS             complement(122..1972)
                     /locus_tag="VUR43_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET5413776.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(2014..3171)
                     /locus_tag="VUR43_002155"
     CDS             complement(2014..3171)
                     /locus_tag="VUR43_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET5413777.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENVEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            3229..4395
                     /locus_tag="VUR43_002156"
     CDS             3229..4395
                     /locus_tag="VUR43_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET5413778.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLTIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIYILMTVALFTVDRADKIL"
     gene            4534..4860
                     /locus_tag="VUR43_002157"
     CDS             4534..4860
                     /locus_tag="VUR43_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET5413779.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            4847..5440
                     /locus_tag="VUR43_002158"
     CDS             4847..5440
                     /locus_tag="VUR43_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET5413780.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            5433..6344
                     /locus_tag="VUR43_002159"
     CDS             5433..6344
                     /locus_tag="VUR43_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET5413781.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            6407..7471
                     /locus_tag="VUR43_002160"
     CDS             6407..7471
                     /locus_tag="VUR43_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413782.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIANLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLKSPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
BASE COUNT         2291 a         1730 c         1323 g         2236 t
ORIGIN      
        1 aaccatatac ggcaaggcga cgttgacgtg gtttgaagag attttcgaag agtataagtc
       61 tctacataat aaaacgcata ttaccaaggt tgtgtaactt gatactatgc gtttttcttt
      121 tttattcaat gtgggttgtt tgattagcaa aggcgataat agcttgcttc aactcatctc
      181 cactgagagt gcggaactct ccaatctttt gattgatgga ttctaaaggc atgacattaa
      241 ccttaccaac gaaaatctta tccataactt gattatcaac gagttcggtt gataccaaga
      301 gttcttcgta gagtttttca cctgggcgga ttccaacttc aacgattgga atttcacttt
      361 cagtgtggcc acttagaagc accatcttct tggccaagtc ataaatcttg actggtttgc
      421 ccatatcaag gataaagact tccccatctt tggcataagc accagcatgg ataaccagac
      481 ggctagcttc tggaatggtc ataaaataac gggtcatgcg gaagtctgtc accgttacag
      541 gcccaccttc agcaatctga cgttcaaaga ctggaatgac actaccacgg ctaccaagaa
      601 cattcccaaa acgaactgca cagtaggttg attggctacg ttggttaaag ccagtgacaa
      661 tcaactccgc cacgcgcttg gttgctccca taacatttgg tggattgact gccttatctg
      721 tcgaaatcat aaccatctta gacactttag cttcatcaac agccttagca acattgtaag
      781 ttccacggat attgtttttg aaggcttctt ttggattgcg ctccatcata ggaacatgct
      841 tgtgggctgc cgcatgataa acaatagcag gtttgtactg ctcaaagact tgcaacaaac
      901 gatcatagtc ttgaatgtcc gcaatcacag gtacataatc aatcccttgg aacttacgaa
      961 tcaattcatg ataaacaagg tagattgagt tttccccatg accgagcaag acaatgcgtt
     1021 caggattgaa gcgactaact tgacgacaga tttcagaacc gattgaacct ccagctcctg
     1081 tgactaagat ggtcttacct gtcagttctg cacccagacg cgattcgtca agacggattt
     1141 cctgacgacc caaaaggtcc gtaatatcaa ttttttggaa gccagtacct gcttggtgaa
     1201 ggccctgaac aacagtttca accttaggca tcttgtaaca tttgacaccc agcttattac
     1261 acatctgcaa gatacgctca tattctgacg gatccagcga cggaatcgca acgatgacac
     1321 gctcgatttg atggcgtttg gctaattcag gcagattgtc ataagagccc aaaacaggaa
     1381 taccaccaag tttttgaccc tttttcttag aatccttatc caaaataccg accagttcta
     1441 attcactggt tggatgttgg taactatcca taaaaagagc cccaccatca ccggcaccaa
     1501 tcaagaaggt ccgacggtgt tctccatcac cactaccttt tttgcgtctg gagtagatta
     1561 actgccaagt aatccgtggc aataaaatca agaaggtact caacaagata aagagaatga
     1621 tgaaacggat ggagaagagt ggcaagaagg cataacagat actatatgac aagacactgc
     1681 tagcagtcac accaaaaaag attttcatga aatccgtaat cttgctgtaa cgactaatgc
     1741 tcgcgttcaa cccccaaaaa ccaatcatca attgatagaa caggaaggcc aaactcgtat
     1801 agataatgta gtcaacaggt gctggattaa tcagcccata aaataaaata taagatacaa
     1861 tgatggaaac caccatactg aaaatatcaa atattcccca gaaaacctgc ttttgttgtt
     1921 tatttaaaat ttccaccaga tcaatcacat aatctgttag ttttttattc atagaaatct
     1981 actcctcctt aaaagagttt tactatattg ttattatagc atatttttgt ttatttggct
     2041 tattttatcc aaataaatta ttgttctctt gtactccttc ttccatttaa atcctctaat
     2101 taaacctaca atcgtcccaa agccataagc aaagtgaatg gaaaataaaa gaaagggcat
     2161 cacaattaga aatccatttt tatgttttaa taaagtcagc aaagtgagta gtgacaaaag
     2221 tagaaaatag gcacctaata gtaaagttat gaatacgaat gtgatcggta acaatgctag
     2281 actaaacaca agactcaaaa caaataaaca aggaacatag tgaaataatg ataaacactt
     2341 aaactgaaca tgacttgtca agccaatcca caaaccattt gaatactttt gatgcagcat
     2401 tttcttgaat gttggtcgaa tatactgata agatagaata cttgggctat agcggatttt
     2461 ataaccatgt tctcgaattc tataatgaat atcattatct tcagttcggc caagttgctc
     2521 atttactaaa ccaaccttct ggaaaacctc tcgtttatac atcccatgaa aaatagaaga
     2581 aacatatcta tcctcggaac tatttcgata attggcaatg ctactgccaa acatattttc
     2641 ctcaacaaga tgcaaggtct ctgcccattt tccttttcct tcgacaatcg tcggtctagg
     2701 ccccccacag acaaattcac cttgttgaat aatagccaca ttgttcatta caaaactctc
     2761 agtaactttt gaatgagcat caatttttaa aataaggtcc cctacagaat gtttaactcc
     2821 caggttaaaa ccactagctt gatttttctt aggattgtta tacaatctaa ttgagttaaa
     2881 ctctgtatct tcctttataa attgctgaat gatagctgtg gtcccatctg tggacatagc
     2941 atttataaat agaatttcaa cattctcttt aggataggtt tgatttttta agtcttcaat
     3001 tagaccaggc agatattttt cttcattgta tgcactgatt acaatggata cgagaagact
     3061 ttcaacattt tgagtcacta ctactctcct gaatttttcc ttccaccatt ctatcataat
     3121 tttcaagact ttcccatttt tatcttgaaa gccagaaacc ttacttgaca ttatagtgaa
     3181 aaagccttaa aataagctgt tattaaaatc agctagaaga ggtattatat gaaaaagcaa
     3241 tcactctttt ttgttccagg tattatcctg attggtgttt ccttgcgaac tccttttact
     3301 gttttaccca ttattttggg aaatatttcg caaggtctgg aggtagaagt tagttcgctt
     3361 ggtgtcttga ccagcctgcc tctccttatg tttaccctct tttcaccatt ttctacccga
     3421 ctggctcaga aaatcggctt ggagcatctc ttcacctaca gcctcttctt cttgaccatc
     3481 ggctcactca ttcgactaat caatctgccc ctgctctatc taggaacctt gatggttggg
     3541 gcaagtgtcg cagtcatcaa tgtcctgctt cctagtctta tccaagccaa tcaaccaaag
     3601 aaaattggtt ttctgaccac cttatatgta acgtctatgg ggattgcaac ggctctggct
     3661 tcctatctag ctgtgcccat tacacaagcc agttcttgga aaggacttat cctcctcctc
     3721 acgttactct gtctagcaac ttttttggtc tggctcccaa atcaccgcta taatcataga
     3781 ctagctccac aaaccaaaca aaaaagtcaa ataaaggtca tgcgtaataa acaggtttgg
     3841 gcaattatta tcttttcagg ttttcaatcc ttgatctttt acaccgtcat gacctggtta
     3901 cctaccatgt ctatccatgc aggtctatcc agtcacgaag ctggcttgct gacttctatc
     3961 ttatctctga ttagcattcc tttttcaatg accatcccaa gcctgacaac cagtttatct
     4021 actcgcaacc gtcagctcat gctcactctg gtttcactag ctggtgtggt cggcatttcc
     4081 atgctctttt tcccaatcaa taatttcatt tactggctta ccatccatct cctcatcgga
     4141 accgcaacca gcgccctctt cccttatctc atggtcaact tttcactcaa gacaagcgcc
     4201 cctgaaaaga cagcccaatt gtccggccta tctcaaacag gaggctatat cctagcagcc
     4261 tttgggccaa ccctctttgg ttacagtttt gacctgttcc actcttgggt accagctgta
     4321 gctgccctct tgctcatcta tatcctgatg actgtggccc tctttacagt ggacagagcg
     4381 gataagatcc tttaaacttc tagttttagc tagaagtttt ttatatataa aaattttaca
     4441 catttctctt gacagggctt tcttttagat gtacaatgta tgtgtagaaa aattatatat
     4501 aaaaatctta cacattagaa aaggaggttt cccatgtact ttccaacatc ctctgccttg
     4561 attgaatttc tcatcttggc tgtactggag cagggtgatt cttatggtta tgagattagc
     4621 caaaccatta agctgatcgc taatatcaaa gaatccacac tctatcccat tctcaaaaaa
     4681 ttggaaggca atagctttct gacaacctat tctagagagt tccaaggtcg catgcgcaaa
     4741 tactactcct tgacaaacgg tggtatagag cagctcttga ccctaaaaga tgaatggaca
     4801 ctctatacag acaccatcaa tggcatcata gaagggagta tccgccatga caagaactga
     4861 atacctgact cagctagaac tctatctcaa gaaactacct gaagctgacc gtatcgaagc
     4921 catggactat ttcagagagc tctttgacga tgctggagtc gaaggagaag aagaactcat
     4981 cgctagtttg ggaactccca aagaagcggc ccacgaagtt ctatccaatc ttctcgataa
     5041 aaaaatcaat gaagcacccg ctcaaaaaaa taaccgacaa attttacata tcgccttgtt
     5101 agccctcctt gcagcaccta tcggcattcc tctgggaatc gccatcctcg tgaccctgtt
     5161 cgcaatcctt gtagccgctt tgactgtcat tctggctttc tttgcagttt ccatactggg
     5221 tatcatcggc ggattcctat ttttagttga aagtttcact atcctcgccc aagccaaatc
     5281 agcctttatc ttgatttttg gttctggttt actggctatc ggtgcttctt cgctagtttt
     5341 acttggcatt tcctatgtag ctcgcttctt cggtctactc attgttcgtc tggtacaatt
     5401 tgttcttaaa aaaggaaaga gaggtaatca gcatgcgtaa atggacaaaa ggatttctca
     5461 tctttggtgt ggtgactacc gttatcggct ttatcctgct ttttgtaggt atccaatctg
     5521 acgggattaa gagcctactt tccatgtcca aagaacctgt ctatgatagc cgtacggaaa
     5581 agctaacctt tggcaaggaa gtcgaaaacc tagaaattac tctccaccaa cacacgctca
     5641 ccatcacaga ctctttcgat gatcaaatcc acatttctta ccatccatct ctttctgctc
     5701 accatgatct tatcaccaat cagaacgata gaactctgag tctcactgat aagaaactgt
     5761 ctgaaactcc gtttctctct tctggaattg gtgggattct tcatatcgca agtagctact
     5821 ctagtcgttt tgaagaagtt attctccgac taccaaaagg gagaactcta aaagggatca
     5881 acatctcagc caatcgcgga caaaccacca tcataaatgc tagccttgaa aatgcgaccc
     5941 tcaatacaaa cagctatatt ctccgaattg aaggaagtcg tatcaaaaac agtaaactca
     6001 caacgcccaa tatcgttaat atctttgata cagttcttac agatagtcag ctagagtcaa
     6061 cagataatca cttccacgct gaaaatatcc aagtccatgg caaggttgaa ctgactgcca
     6121 aagattatct cagaatcatc ctagaccaga aagaaagcca acgaattaac tgggacatct
     6181 caagcaacta tggttctatc ttccaattca caagagaaaa gcctgaatca agaggtacgg
     6241 aattaagcaa cccttacaaa actgaaaaaa ccgatgtcaa ggatcaactc attgcgagat
     6301 ctgatgataa tattgatcta atatccacac caagcagacg ttgacaaaaa cgcttacatt
     6361 tgctactatg gaaacatatt tatctaacta aaaaggaggt tctaccatga aacaagaatg
     6421 gtttgaaagt aatgattttg taaaaacaac aagcaagaac aagcctgaag agcaagctca
     6481 agaggttgca gacaaggctg aagaaacgat agccaatctc gatacaccaa ttggaaaaaa
     6541 tactcaagta gaggaggaag tctctcaagc tgaagtcgaa ctggaaagcc agcaagaaga
     6601 gaaaattgaa actcctgaag gcggtgaagc gagaacagaa atagaagaaa agaaggcatc
     6661 taattctact gaagaagagc cagacctttc taaagaaaca gaaaaagtca ctatagctga
     6721 agagagccaa gaagctcttc ctcagcaaaa agcaaccacg aaagagccac ttcttatcag
     6781 taaatcttta aaaagtcctt atatccccga ccaagctcca aaatctaggg ataaatggaa
     6841 agagcaagtg cttgattttt ggtcttggct agtagaagcg atcaaatctc ctacaagtaa
     6901 gttggaaaca agtatcacac acagttacac agcctttctc ttgctcattc tgttttctgc
     6961 atcttccttt ttctttagta tctatcacat caaacatgct tactatggac atatagcaag
     7021 cattaacagt cgcttccctg agcagctagc tcctttaact cttttttcta tcatctctat
     7081 cctagtagcg acaacactct tcttcttttc attcctcttg ggtagtttcg ttgtgagacg
     7141 atttatccac caggaaaagg actggacgct agacaaggtt ctccaacaat atagtcaact
     7201 cttggcaatt ccaatcttcc tcactgctat tgctagtttc tttgctttct ttgatagcct
     7261 acgatttaca gccctcttgt gtgtgattag cattggaatc attctgcttg ccagtctcca
     7321 tatcattaca agaccaagtc aagcaagtga aaccgactcc ttctatcaat tattcttgtc
     7381 tgtccttgtg aacggagtta ttatcctcct cttctttgta gctgaagtgg cactgattgg
     7441 agattatctt cgtatcttgg cctttcttta aacttcatac tcttcgaaaa tcaaattcaa
     7501 accacgtcag cttcgcctta ccgtactcaa gtacagcctg cggctagctt cctagtttgc
     7561 tctttgattt tcattgagta
//
LOCUS       DAVDHC010000060         6488 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVDHC010000060 DAVDHC010000000
VERSION     DAVDHC010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6488
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.060"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            170..370
                     /locus_tag="VUR43_002161"
     CDS             170..370
                     /locus_tag="VUR43_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413783.1"
                     /translation="MVVSASASSTSPQAQEQVDKSELRALSQELDQHLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            395..811
                     /locus_tag="VUR43_002162"
     CDS             395..811
                     /locus_tag="VUR43_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413784.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1042..1749
                     /gene="ccdA2"
                     /locus_tag="VUR43_002163"
     CDS             1042..1749
                     /gene="ccdA2"
                     /locus_tag="VUR43_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET5413785.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1760..2317
                     /gene="sdbB"
                     /locus_tag="VUR43_002164"
     CDS             1760..2317
                     /gene="sdbB"
                     /locus_tag="VUR43_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET5413786.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2692..4083
                     /locus_tag="VUR43_002165"
     CDS             2692..4083
                     /locus_tag="VUR43_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET5413787.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4226..5143
                     /gene="adcAII"
                     /locus_tag="VUR43_002166"
     CDS             4226..5143
                     /gene="adcAII"
                     /locus_tag="VUR43_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET5413788.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5151..>6488
                     /gene="phtD"
                     /locus_tag="VUR43_002167"
     CDS             5151..>6488
                     /gene="phtD"
                     /locus_tag="VUR43_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET5413789.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSD"
BASE COUNT         1988 a         1205 c         1367 g         1928 t
ORIGIN      
        1 gtaaaacgaa ataagaatag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ctatatgtac tattctagtt tcaatatacc ataactgctc ctagtcaacc
      121 tgcaagtcct gtcccagctc caagctcagt tccgactcaa gatcctagag tggtagtaag
      181 cgcttcggct agctcaacga gcccacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagttag accaacactt gaaagctttg gcaacagtat ctgatccgaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgccttgg actctctcaa
      421 agatgtgaaa gcaaatgcta gcgacagcaa gcctgcacag gacaagaagg atgcaaaaca
      481 aggaacggaa gatagtaagg attcagataa gatgactgaa acaaactcag ttccggcagg
      541 agtgattgtg gtcagtctac ttgccctcct aggcgtgatt gccttctggc tgattcgccg
      601 taagaaagag tcagaaatcc agcaattaag cacggaatta atcaaggttc taggacagct
      661 agatgcagaa aaagcggata aaaaagtcct tgccaaagcc caaaaccttc tccaagaaac
      721 ccttgatttc gtgaaagaag aaaatggctc agcagagaca gaaactaaac tagtagagga
      781 gcttaaagca atccttgaca aactcaagta aaacatgatt tatgaaatgt cagacttaaa
      841 agacattttc gttcacaaaa gcagcgacga gtaatccttg tcgttgcttt ttggctattt
      901 tgggggataa gatccgcctt gactagcaaa agaaaagatt ggtccaatag tgcccgatac
      961 gattttgcgt agcagaaagc ttacaaataa aattgaatat agtaaaatag gattagaatt
     1021 attaagaaag ttggttcttt attggaaacg atagtatttt taatctctgt ttttctagca
     1081 ggtgttttat cctttttttc tccttgtatt tttcctcttc tgccagtcta tgctgggatt
     1141 ttattggatg atcaagaaag tgcaaaaagc ttttctttgt ttgggagaaa ggttctctgg
     1201 tcaggcttga ttcgaacact ttgctttatc gctggtatct ctctcatttt ctttattcta
     1261 ggctttggtg ctggttactt tggtcatatt ctctatgcaa attggtttcg atatggcatg
     1321 ggagctatta ttatcatttt gggtcttcac cagatggaaa tttttcattt gaagaaatta
     1381 gaagttcaaa aaagttttac ctttaaaaaa tcagattcta atcgttattg gtcagctttt
     1441 ttacttggta ttacctttag ctttggttgg acaccttgta ttggtccagt tttaagttct
     1501 gttttagcac ttgcggcttc tggaggcaat ggcgcttggc aaggagcgat ttatactctc
     1561 atttacactc tgggcatggc ccttcctttc ttggtattgg cactagcttc aggtctagtc
     1621 atgccatatt ttagtaaaat caagcgccat atgatgctac taaagaaaat tggtggtttc
     1681 ctcattgttt taatgggaat tttgttacta ttaggacaag taaatgttct agctggaatt
     1741 tttgaataaa ggaggacaaa tgaaaaaagt aatgtttgct ggcttaagtc tcttgtcatt
     1801 agttgtattg atggcctgtg gtgaggaaga aactaaaaag actcaagcag cacaacagcc
     1861 aaaacaacaa acgactgtac aacaaattgc tgttggaaaa gatgctccag acttcacatt
     1921 gcaatccatg gatggcaaag aagttaagtt atctgatttt aagggtaaaa aggtttactt
     1981 gaagttttgg gcttcatggt gtggtccatg caagaaaagt atgccagagt tgatggaact
     2041 agcggcgaaa ccagatcgtg atttcgaaat tcttactgtc attgcaccag gaattcaagg
     2101 tgaaaaaact gttgagcaat tcccacaatg gttccaggaa caaggatata aggatatccc
     2161 agttctttat gataccaaag caaccacctt ccaagcttat caaattcgaa gcattcctac
     2221 agaatattta attgatagcc aaggaaagat tggaaagatt caatttggtg ctatcagtaa
     2281 tgcggatgca gaagcagcat ttaaagaaat gaactagaat cgataaaatc tgattacaag
     2341 atgtagtcag attttggtaa cttctaaaac taacttccag tttcccacaa cctagctttt
     2401 agtatgagaa aaacgcgtga catcagtgga aatccgtctt agactaactt ccactggttt
     2461 tctttttctt gatatataag ggttcaaaag cgaaaagact cagaaaaaag tgcacgacaa
     2521 atagccctaa aacagagtcg ttttagagta acttccagtt ttgggagaga gatggaagtt
     2581 actttgagaa gttacggtag tcagattttt ttagaaaaac attttataaa tattcacata
     2641 tctcctatat ttatggtaaa atagaatcat cagtttattt tggagtcaaa gatgaatata
     2701 tttagaacaa agaatgttag tttagataaa acagagatgc ataggcattt gaagttatgg
     2761 gatttgattt tgctgggtat cggagccatg gtagggacag gcgtctttac aatcacaggt
     2821 actgcagctg caacacttgc tggcccagcc ctagtgattt caatcgttat ttctgccttg
     2881 tgtgtgggat tatcagccct cttttttgca gaatttgcct cgcgagtacc cgctacagga
     2941 ggtgcctata gttacctcta tgctatctta ggagaattcc ctgcctggtt ggctggttgg
     3001 ttaaccatga tggagttcat gacagccata tcaggcgtag cttcgggttg ggcagcttat
     3061 tttaaaggct tgctctctca atacgggata gcctttcctc aggctttaaa tggtaccttt
     3121 aatcctcaag cagggacatt tgttgattta ttgcctattc ttgtcttggt cttggtgact
     3181 tcgcttgttt tactaaatgc caaggcagcc ttacgcttta attcgattct agttattttg
     3241 aaattttccg ctttagctct ctttgtttta gtaggaattt ggaatattaa gtttgataat
     3301 tggagcaatt ttgctcctta cggttttgga caaatctatg gagctagcac tggtattatg
     3361 gctggtgcgt ccttgatgtt cttcggtttt ttgggatttg aatccatctc tatggctgta
     3421 gatgaagtca agactcctca aaaaaatatt cctagaggga ttgtcttatc gctttctatc
     3481 gtaaccattc tctatgcctt ggtgaccctt gttttgactg gtgtggttca ctatagtcat
     3541 ttaaatgtcg atgatgccgt tgcctttgcc cttcgtagtg ttgggattag ttgggcagcc
     3601 aactatgtgt cattagtggc tatcttgacc ttgattacag tttgtatttc gatgacctat
     3661 gccctatcgc gtatgattta cagtttagca cgtgacggct tagtgcctgc tgcctttaag
     3721 gaactgacga agactagcaa gataccaaag aatgctacta tcttgacagg tctagcttca
     3781 gcagtagcag caggaatgtt cccactagcc agtattgcag cctttttaaa tatttgtacc
     3841 ttagcctact tgatcatgtt ggcttatggt ctgattcgct tacggaaaga aaaaggaatg
     3901 cccaaagctg gggaatttaa aacaccattg gtacctctgt taccaatttt atcgatcatc
     3961 atttgtttat ccttcatgtt acagtataat atgaatacct ggattgcttt cctagttgcg
     4021 ttgttagtag gaagtattat ttacttcact tatggctata agcattctac catagaagaa
     4081 taaagtgaaa gtctattgag ttgttgacac tcagcagatt tttatatgtg aaagaaattt
     4141 caaatttttt ctaaaaatat cttgacagat taaattttca ggagtagaat atttactagt
     4201 taattaaatg gttaaggagt tgttcatgaa gaaacaaaat ttatttttag tcctgttaag
     4261 tgtctttctt ttgtgcttgg gggcttgtgg tcaaaaggaa agtcagacag gaaaggggat
     4321 gaaaattgtg accagttttt atcctatcta cgctatggtt aaggaagtat ctggtgactt
     4381 gaatgatgtt cggatgattc agtcaagtag tggtattcac tcctttgaac cttcggcaaa
     4441 tgatatcgca gccatctatg atgcagatgt ctttgtttac cattctcata cactcgaatc
     4501 ttgggcagga agtctggatc caaatctaaa aaaatccaaa gtgaaggtct tagaggcttc
     4561 tgagggaatg accttggaac gtgtccctgg actagaggat gtggaagcag gggatggagt
     4621 tgatgaaaaa acgctctatg accctcacac atggctagat cctgaaaaag ctggagaaga
     4681 agctcagatt atcgctgata aactttcaga ggtggatagt gagcataaag agacttatca
     4741 aaaaaatgcg caagccttta tcaaaaaagc tcaggaattg actaagaaat tccaaccaaa
     4801 atttgaaaaa gcgactcaga aaacatttgt aacacaacat acagcctttt cttatctagc
     4861 gaagagattt gggcttaatc aacttggtat tgcaggtatc tctcctgaac aagaaccaag
     4921 tccacgacaa ctaacagaaa ttcaggaatt tgttaagacc tataaggtta aaacgatttt
     4981 tacagaaagt aacgcttctt caaaagtagc tgaaactctt gtcaaatcaa caggtgtggg
     5041 tcttaaaact ctgaatcctt tagagtcaga cccacaaaat gacaagacct atttagaaaa
     5101 tcttgaagaa aatatgagta ttctagcaga agaattaaag tgaggaaaga atgaaaatca
     5161 ataaaaaata tctagcaggt tcagtggcag tccttgccct aagtgtttgt tcctatgaac
     5221 ttggtcgtca ccaagctggt caggttaaga aagagtctaa tcgagtttct tatatagatg
     5281 gtgatcaggc tggtcaaaag gcagaaaatt tgacaccaga tgaagtcagt aagagagagg
     5341 ggatcaacgc cgaacaaatt gttatcaaga ttacggatca aggttatgtg acctctcatg
     5401 gagaccatta tcattactat aatggcaagg ttccttatga tgccatcatc agtgaagaac
     5461 ttctcatgaa agatccgaat tatcagttga aggattcaga cattgtcaat gaaatcaagg
     5521 gtggctatgt gattaaggta gacggaaaat actatgttta ccttaaagat gcggcccatg
     5581 cggacaatat tcggacaaaa gaagagatta aacgtcagaa gcaggaacgc agtcataatc
     5641 ataactcaag agcagataat gctgttgctg cagccagagc ccaaggacgc tatacaacgg
     5701 atgatggtta tatcttcaat gcatctgata tcatcgaaga tacgggcgat gcctatatcg
     5761 ttcctcatgg caatcacttc cactatattc ctaagagtga tttatctgcc agtgaattag
     5821 ctgctgccca agcctattgg aatgggaagc agggatctcg tccttcttca agttctagtc
     5881 ataatgcaaa tccagctcaa ccaagattgt cagagaacca caatctgact gtcactccaa
     5941 cttatcatca aaatcaaggg gaaaacattt caagcctttt acgtgaattg tatgctaaac
     6001 ccttatcaga acgccatgtg gaatctgatg gccttatttt cgacccagcg caaatcacaa
     6061 gtcgaaccgc cagaggtgta gctgtccctc atggtaacca ttaccacttt atcccttatg
     6121 aacaaatgtc tgaattggaa aaacgaattg ctcgtattat tccccttcgt tatcgttcaa
     6181 accattgggt accagattca agaccagaac aaccaagtcc acaaccgact ccagaaccta
     6241 gtccaagtcc gcaacctgca ccaaatcctc aaccagctcc aagcaatcca attgatgaga
     6301 aattggtcaa agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag
     6361 tttctcgtta tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca
     6421 aactggccaa gcaggaaagt ttatctcata agctaggagc taagaaaact gacctcccat
     6481 ctagtgat
//
LOCUS       DAVDHC010000061         6209 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVDHC010000061 DAVDHC010000000
VERSION     DAVDHC010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.061"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(468..690)
                     /locus_tag="VUR43_002168"
                     /pseudo
     CDS             complement(468..690)
                     /locus_tag="VUR43_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(848..1102)
                     /locus_tag="VUR43_002169"
     CDS             complement(848..1102)
                     /locus_tag="VUR43_002169"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET5413790.1"
                     /translation="MGTKIGISKNTIGNYEKRVRSTKKNTIFDLVKVFSSLIDALFSP
                     VQKDSPSDIQSIYDQRAPPRQGKVLTYAERQLYDQKNEVS"
     gene            1538..2410
                     /locus_tag="VUR43_002170"
     CDS             1538..2410
                     /locus_tag="VUR43_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET5413791.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLDTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2559..2900)
                     /locus_tag="VUR43_002171"
                     /pseudo
     CDS             complement(2559..2900)
                     /locus_tag="VUR43_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3043..3354
                     /locus_tag="VUR43_002172"
     CDS             3043..3354
                     /locus_tag="VUR43_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413792.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            3358..4074
                     /locus_tag="VUR43_002173"
     CDS             3358..4074
                     /locus_tag="VUR43_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET5413793.1"
                     /translation="MKKYFIGGLGNNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYLTSEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVLDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4204..5019)
                     /locus_tag="VUR43_002174"
     CDS             complement(4204..5019)
                     /locus_tag="VUR43_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET5413794.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5016..5921)
                     /locus_tag="VUR43_002175"
     CDS             complement(5016..5921)
                     /locus_tag="VUR43_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET5413795.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
BASE COUNT         1971 a         1072 c         1245 g         1921 t
ORIGIN      
        1 aaataagata tgcacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagcaa
       61 tcgtaatgta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaaccttcaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aatttacata tcactattgt
      361 ttaacaaaat ctaatctatt ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctccctatat
      481 agcctgacaa ctttcccgat ggtacgaata tggttgcttt cgtctaggtg gatgtcgggg
      541 tatttgggat tgagtttttt taaggtagcc ttggcggagt ttcttgacat agttagcgcc
      601 gtctacttgg aagatgccga tggtattata gtcaatctgt ggggtattct tgataaatag
      661 gtagtcgctg tttcttatct ttggctccat ggacttgctg acgacataag cgattgggtc
      721 gtagtcgtct gggataatgg aaactccata tctaaatcgt tgtcctgcat cgagcggcta
      781 cctgcagaga taaactacct aacacgagag taagtagtct gtctgtagtc gtccagtctg
      841 atgattttta cgatacttcg tttttctgat catacagttg cctctcggca taggtcagaa
      901 ctttaccttg tctgggtggt gcccgttggt cgtagataga ttggatatcg ctaggagaat
      961 ccttttgaac tggagaaaag agggcatcaa tcaagctact gaatacttta actaagtcaa
     1021 atatagtatt tttcttagta gatctaaccc ttttttcata atttccaatg gtgtttttac
     1081 ttataccaat cttagtaccc aattcttatt gagtccaacc attactagtc tatattgttt
     1141 tatagttgat tgagtttgga atagtacgct gtagctgcta aaacatttct aggaattaat
     1201 ttgcctttcc taatagagtt gttcatatct tatttcaatc tactatattt ttcgcctcta
     1261 acaatcgcaa tctcttcttt atctacgaat gaaatcgctt tctatttttg taagtaaagc
     1321 atcacacgaa atccacgaaa atgaaaacct ttgttgtgtt ttcgtaaaaa atttgttgac
     1381 agagcacgaa acgcctacta taattaaatc aagcttaagg aaataacaaa aaaacaaatc
     1441 ggagggaaag acgatgaaca cattaaatga gaaagtaatc aatatctgta aagcagtagt
     1501 taaagaaact ttaatccaag acatttagga gaaagaaatg aagaaatcaa gaaaattagc
     1561 cacattagga atctgttcag ctttgttttt aggcttggct gcttgtcaac aacaacatgc
     1621 tacttctgag gggacgaatc aaaggcaaag cagttcagcg aaagttccat ggaaagcttc
     1681 atacaccaac ctaaacaacc aggtaagtac agaagaggtc aaatctctct tatcagctca
     1741 cttggatcca aatagtgttg atgcattttt taatctcgtt aatgactata ataccattgt
     1801 cggctcaact ggcttatcag gagatttcac ttcctttact cacaccgaat acgatgttga
     1861 gaaaatcagt catctctgga atcaaaagaa gggcgatttt gttgggacca actgccgtat
     1921 caatagttat tgtcttttga aaaattcagt caccattcca aagcttgaaa agaatgacca
     1981 gttgcttttc ctagataatg atgcgattga taaaggaaag gtctttgatt cacaagataa
     2041 ggaagagttt gatattctat tttcgagagt tccaactgag gcaactacag atgtcaaggt
     2101 tcacgctgaa aagatggaaa cattcttctc acaatttcaa ttcaatgaaa aagctcgaat
     2161 gctgtctgta gtcttgcacg acaatctgga tggcgagtat ctgtttgtag gccacgttgg
     2221 ggtcttagta cctgctgatg acggtttctt atttgtagag aaattgactt tcgaagagcc
     2281 ctaccaagcg attaaatttg ctagtaagga agattgctac aagtatttgg acaccaagta
     2341 tgcggattat acaggcgagg gactggctaa gccttttatc atggataatg ataagtgggt
     2401 taaactttaa tagtgttatg atatgacagt aatcttagga tttttatttc tatttttgat
     2461 gagttggtgg gttatttcaa tcgttaatag ccagaaacca cgcaaaaatg aaacatttat
     2521 tggctatgtc caaagatacg atattgatgg gaatggctat caatcattac cgtgtcctca
     2581 gaactgagag gagttcttga aatcgtaaaa ccactttgaa caagagttac ttcaacccat
     2641 tggctccgac ggattaagtt gctttcgtga ataccaaaat cagccgcaat ttcttcataa
     2701 gtgcggtatt ctcgcacata ttgaagagtg gccataagaa ggtcttctag gcttaattta
     2761 ggttttcgtc caccttttgc gtgtttaagt tgataagctg tttttaatac agctaacatc
     2821 tcttcaaaag tcgtgcgctg aacaccaaca agacgcttaa atcgtgcatc agttagttgt
     2881 ttacttgctt cataattcat agaactatta taccatgttt tgtttcgcag gaaatctaat
     2941 gctaaaatct tatcagtgag aagatttctt aaagtttatt ctttgtagtt tcatctgtat
     3001 tagtacataa tttaacttag agaaaatagg aggactaatc gaatggaatt aaaagatttt
     3061 acagaaaaag aacaggaaat gattaagaaa aggcttacaa tgtctaatat tagtgacaaa
     3121 gaaactactg agaagattct ggcgctagta ccacaagact tgattaagcg aatcccgttt
     3181 tttgtcagaa aacatgctac aacacgtacg attaaacgca tttcaattga acaccctgaa
     3241 ctctacgctg tagctcaaac aagtggtgag attccagaaa aagaacgcga agaattgcgt
     3301 cagattatca caactatctt tgaacaaaag atgaataagc atagtattaa gtagagaatg
     3361 aaaaaatatt ttattggcgg tttgggaaat aatgcctatc atagcaagga ttttcttcaa
     3421 gaactagatt cgcaggtcta ttttctaaat ccatatgaaa agcatcttcg agatgaaaca
     3481 gaattgaaat catggtttaa aaatgagatt gtagaggaag aatctatctg tctgataggc
     3541 cattctcttg gaggagattt agctcgttat ctcacatcgg aatttgaaga agtaaagaaa
     3601 ctgattcttt tggatggtgg ctatctagat ttagataaga ttttaccttt ggatacagag
     3661 ttagaggaaa ctaaaaatta tatcaaatct caaattgttt tggacttagc tcttcttatt
     3721 tctaaagaaa aatctgaagc aaagcattgg tcagaaaata tggagaaagc tgtaagacag
     3781 tcttatcact ggaatgttga gtataataga tatgagttgg ctataaatta tgaaaatata
     3841 gaagcgatac tccgcctacg gagaaaaata caagctttta agagagaagt gggagatacc
     3901 ttgtttatta gtcctcgcta tcctaatgaa gctacatgga gagaggaagc cctaaaagaa
     3961 ttgccagact attttgatac tattttttta gaaaactttg gccatgagct ttatactcaa
     4021 gcacctaaag aaatcgctag tctaatgaat gagtggctcg cttattttct atgagctact
     4081 tgtattgctg gaaatggtat aagatgaaaa tctacaagtc actaattttc atataacaaa
     4141 aaaacgaaca ggctcttttt ctgttattca gaagagaact tgttcgtttt tatcttgatt
     4201 ttcttaaaaa gctctatata catagggatt ttctggttta tcgactttgg taaagctgtc
     4261 gatttccaag gttggaaggt tttgtttgag ttctttatgg tagtgattga ccagttttcc
     4321 tttggctgaa atccaagtgt tgttttcata ctgccgggta ttgcccttgg tcagcaatcc
     4381 atagacacca gaatctgcga tacagtggat aatgccgaat cggaacagaa attgactatt
     4441 ggcatgactg gggtcgttat agacaaagcc tgtaaactgg attgtcttgc cctcaaactc
     4501 atctggatag tcgtagatag cctccatgac ttccatatag ttttcattag tgatctgaat
     4561 actatcttgg gataagtatt tatccgccgc cgttcgcatt tccttttcat aggctgattt
     4621 tgaaaaataa gaactggtat ctggtttcaa atattggctt gtcgtccctt cgcttgtctg
     4681 aatggctaga tccgttcctt ccgatagggg gaaatgataa cctttagcag aaacagtctg
     4741 agaatccaag ctaacagttg ggaaagttaa gccgatgaca agtggaatag ccagaagaga
     4801 aatactcgtc atcttggcca atcggctgtt cagatgactg tgggttttga cttgcttcat
     4861 ccagatatac aattgaacaa ttgccaagat aaaggaaagc accatggaaa tataggccag
     4921 ataggaatag tgcatgttga tgtactggtt tagtttgccc gacagatgga ggtaaatagt
     4981 cagttcaaaa tagccagcta aaactaaaaa tcgaatcata ggatgactcc aatcaagaga
     5041 gaataggcta aaacgaccag agtcacaatc gtaatgaagt gactaataaa tcgtgctttc
     5101 aagtaatttt tcatcatgag aatatttttg atatccagca ttgggccaat gacgagaaag
     5161 gccagaactg gagccaaacc gaaactcgag agtagagaag cacctataaa ggcatccgcc
     5221 tcactacaga gcgaaagaag aaaggccaaa agcatcaaga gcaggatggc aaaaagagga
     5281 gtcgcactga tagaggtcag aatccgagtc ggaacgtaga cctgtattat agaagcaaag
     5341 aggcagccaa ataccaaata acgccccgta tcaaaaaatt catcaatggc ctgcacaaag
     5401 acttgaaaaa ctttttttgc agaactcaag taagaaaaat catgctcatg acaagccaga
     5461 cgattttctt tctgaatcgg ttcttgccag aaaaatccta gaaaaattcc tagtattaca
     5521 gccacaagaa tggaacccag agctcgtaat agggcgacat ggaaggagtt gccaaaggca
     5581 gaataggtcg caaaaagaac aatgggattg ataacaggtg ctgtcacaag aaaaggaact
     5641 gccgtgtaac ttggaacctt tttttccaga aaacgattga tgatggggac gattccacat
     5701 tcacaagaag ggaaaagtat accgacaaag gtcccaaaaa agattctccc ccaacgattt
     5761 cgagggagaa aatgataaac cttgtcaggt gtgatataaa cttcaatcag ccctgagaca
     5821 atgcttccta tcagaacgaa gggaagggct tcaatgataa tggagagaaa aatggctcca
     5881 gtttgaagta cactagatgg gagttgttga aaagcagtca tctagttttt cttttctgct
     5941 ttgacttttt tctctttgtc atcagggaaa gtaacttgtt tcaaatcagg gagtttagca
     6001 aactcttcaa acatcttgtc caagtcgtct cgttttgtaa atttgacagc cataggtgta
     6061 cctcgattct aaattctacc tctattatac tattattttg cggaaaaggg agttttttaa
     6121 tttgttttcg atagttgata cacttcgaaa atctcttcaa accacgtcag cttcgcctta
     6181 ccgtagtacg gttactgact tcgtcagtt
//
LOCUS       DAVDHC010000062         6204 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVDHC010000062 DAVDHC010000000
VERSION     DAVDHC010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6204
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.062"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            1702..3083
                     /locus_tag="VUR43_002176"
                     /pseudo
     CDS             1702..3083
                     /locus_tag="VUR43_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            3064..3267
                     /locus_tag="VUR43_002177"
     CDS             3064..3267
                     /locus_tag="VUR43_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413796.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            3270..3620
                     /locus_tag="VUR43_002178"
     CDS             3270..3620
                     /locus_tag="VUR43_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413797.1"
                     /translation="MAETNQNTDNLLDLTKITEPFELASALRYMKENGEFIRCKNVSD
                     DFYMYRDVQKRPVIVNGRRQFKDVETVWAFNQWGGTIATINVAVLLNHEFYIMKFDAE
                     GNPDWTVPTVEPKE"
     gene            3629..4045
                     /locus_tag="VUR43_002179"
     CDS             3629..4045
                     /locus_tag="VUR43_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET5413798.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            4049..4381
                     /locus_tag="VUR43_002180"
     CDS             4049..4381
                     /locus_tag="VUR43_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET5413799.1"
                     /translation="MQQITEIIIAFATSFLTVAVGGIVKAVKDYLLRKGGEKAVIIAE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGR"
     gene            4385..5341
                     /gene="lytA"
                     /locus_tag="VUR43_002181"
     CDS             4385..5341
                     /gene="lytA"
                     /locus_tag="VUR43_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET5413800.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGCIMQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKYTDGNWYWFDNSGEMATGWKKIADKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(5561..5740)
                     /locus_tag="VUR43_002182"
     CDS             complement(5561..5740)
                     /locus_tag="VUR43_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413801.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(5882..6031)
                     /locus_tag="VUR43_002183"
     CDS             complement(5882..6031)
                     /locus_tag="VUR43_002183"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413802.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
BASE COUNT         1993 a         1133 c         1403 g         1675 t
ORIGIN      
        1 gataagactt tagttgtatc tgaagctggg aaattgcgtg aagaattttc aaaaatgaag
       61 gtgggaggac ggaatctatg gataaaatcc aagacggttg gagctgtaat tgaaaaatta
      121 cctgaaaacc acgtcacagg tcaaaaagaa tgctataggc tagagaacaa ctctacttta
      181 acgttcaacc ttgaaccaga tttcagctca aggttgtacc aaaaagttac ttttagcgct
      241 tggatcaagt acgaaaatgt agtccaaggt cgaaattttt ggaatgtatt taattgcttc
      301 aaacattatc tttttagaaa aaatagtgag accggagtac agagtggtcc agattatgct
      361 acgcttggta tgtataaagg ttcggcagat tggaaatata ttacattcac ttatgactac
      421 tctgaaaaaa caaattttga tcaattgaag acatcattgc gattcaatct tgaaggtgct
      481 acaagcggta cagcttgggt aacaggaatc aaggttgaaa tcggtagtgt ggcgacggac
      541 tggagtcctg cgcctgagga cgctgatggt ctcatcactg aagctaaggc tacctttgag
      601 cggacagctc agggcttgcg aaccgattta tcagctattc aggaatatgt aaataaaaac
      661 ggtcagcgac aggaagccct acagcgctat actcgtgagg agagcgcgag acaagcgaca
      721 gcagtccgtg agctggtcaa tcgtgatttc gttggtaagg ctacttatca agaagatgtt
      781 aagggtatca atcagaggat tgaagctgtt aaaactagtg cgaataaaga catcgctagt
      841 caaatcgcta gctatcgtca atctgtagat ggtaagttca cggatatttc aagtcagata
      901 actacttata agcaagatgt gggcggtcaa atcagtggtc tttcaaatag acttacaagc
      961 agtgagcaag gaaccactac tcagatttca aatatttcaa atcggataaa cagtaacaaa
     1021 caaggcacag ataatcagat ttcaaattta aagactcagg tcgctacaaa caaggataat
     1081 gctgaacgac aaatgggtag aatatctgat caggtttctg caaacaaagc gaatgctgat
     1141 agtcaatttg cgaatgtgac caatcaacta gcgcgaaaag tagagactac tgagttccag
     1201 cgtgttaagg aaaccagtaa actttacgag cggattttgg gcaatactga aaatggaatt
     1261 gcggataagg ttgctcgcat ggctctgacc aatcaactat ttcaggttga ggttgggaaa
     1321 tatagtgtaa gcggccctaa cctcattaag aatagtgatt ttaaaaatgc tacgaatgaa
     1381 tggggctcaa ctcaaaattt aggaagattg gttaagcata gcttttatca caacgggcag
     1441 aaagacctta tgcgtttaag taatgcaact aaaaacgaaa actttttgta tagtcaccgt
     1501 tttaatcttg aacgaaatac tgactatgta ctgaatttta gaggatttaa caacagtgct
     1561 ctagcaagct atgatgttta tattttggga cgaagagcag gcgagagcga tggattcaca
     1621 atcgttaaga aagttgttag cagcaagaaa ctatctacct ctagatgcga agatgtctca
     1681 gtaactttta attccggaga aatggataat gcttacattc gttttgataa caatggctca
     1741 tcatcaggaa cagctgattt gtatattaca gaagttgact tgtacaaagg ttataaacct
     1801 agaacatggc aaccacatcc agaagatgca gtcgcagatg cgaataagaa gcttgaggca
     1861 acgcaaacaa aaatgactca actagctggc tcatgggtag ttgaaaacat caactcggct
     1921 ggagatatca tctctggaat caatcttggc gccaatggac ataaccgctt cgttgggaaa
     1981 ttgacccaca tcactggaga gaccctgatt gacagagcag tcatcaagtc tgccatggtt
     2041 gataagctga aaacgggcaa ttttgaagct ggttcggtca cgactacgat attagacgct
     2101 gaagcggtaa ctgctgagaa gttgaaagtt gacgatgcgc ttattagaaa attaactgca
     2161 aatgatgctt ttattgaccg actgacatct aaacgtatct tctctactaa ggttgagtcc
     2221 gtcatttcta gttcaacctt cctagaagcc tatcaaggtc gaattggtgg attcacactt
     2281 ggtcaatttg accagggtgg cggtcgctgg atttcaggtg tcaatcagtt ctctgttggt
     2341 atggggaatg gtgccgggca tggagtccgg acagccttct gggcgaactg gggaaataat
     2401 tggaactatg ccggacctaa agcatggaac gtcaatactg atgggaaaat gtactgtagg
     2461 aatgaagtcg gtttttatga tcaagtggat ttttcgaatt catcgagagc aaacttctat
     2521 gggaatacta ctttttctcg ttctcctgtg ttttcaaatg gtatcgaact tggaagtaaa
     2581 gatgtgcttg gtgatggttg gaatcccaaa ggcggaagga atgcggttgt ttggtggaat
     2641 caggtcggta gcggtagctt gaagtattgg atggaacaaa aatcagatag acgcttaaaa
     2701 gagaacatca cagatacagc tgtgaaagcc ttggacaaaa tcaacagatt aagaatggtt
     2761 gcatttgatt tcatcgaaaa taagaaacat gaggagattg gtctaatagc tcaagaggct
     2821 gaaaccatcg ttccaaaaat tgtctcacga gatcctgaga atccagatgg ctatctgcat
     2881 atcgactata ccgctttagt tccttactta atcaaggcta ttcaagaatt aaatcaaaaa
     2941 atagaaaaaa tggagaaaac aatagcatga ataacaacat gttgaccaat atcgcactta
     3001 aagcaattta ggagcttgct cttgaaaata gaaaacgaac acacagattg gagaacttag
     3061 aaaatgaaca cagaacagct taaccaagcc ttacaaatga caattagtga aatgtcaaca
     3121 acttcaacaa attcgatgat tacaagtaat atcttgagta ttcagttgaa tgagcaaagg
     3181 gaagagaatc aaagacttca agcacgagtg gatgagctgg aagctctgct tgatgaacaa
     3241 actaaaccag cagacaaagg agaatagaca tggcagaaac aaatcaaaac acagataact
     3301 tactagacct tacaaaaatc acagaaccat ttgagcttgc gagcgctttg cgctacatga
     3361 aagaaaatgg agagttcatt cgttgcaaga atgtaagcga tgacttctat atgtatcgtg
     3421 acgttcaaaa acgtcctgtg atcgtaaatg gccgtcgcca attcaaggat gttgaaaccg
     3481 tttgggcgtt caaccagtgg ggtggtacaa tcgcaacaat caacgtagcc gttctgttga
     3541 atcatgaatt ctatatcatg aaatttgatg cagagggcaa tcctgactgg acggttccaa
     3601 cggtagaacc taaagaatag gaggttgtat gcaaattgaa tttttcaatt ttctaagaag
     3661 tgtcgtacag actgaagatg gtttggtttt gtacgctcta gcactgattg tctcaatgga
     3721 aatcattgat tttgtgacag ggacgattgc ggcgattatc aatcctgaca tcgagtacaa
     3781 gagcaaaatc ggcattaacg ggctccttcg taagatttca ggggttctct tactgatgat
     3841 cctcattccg gcgtccgttt tgttgcctga aaagacaggt tttgtattct tgcactcaat
     3901 ctatctcggg tacatcgcat ttacttttca atctctcatt gaaaattatc gcaaattaaa
     3961 aggaaatgtt actctttttc agccgattgt aaaagtattt cagcgattac ttgaaaaaga
     4021 tgatgacacg aaaaaaggag aataacaaat gcagcaaatt actgaaatca tcattgcttt
     4081 tgcgacaagc tttttaacag tagcagtagg cggtattgta aaagcagtaa aagattatct
     4141 tttgcgtaaa ggcggagaga aagcggtgat catcgctgaa attctagcta aaaatgcagt
     4201 aaatgccgtg gagcaggtag ctgctgaaac tggctacaag ggagatgaaa aactggcaca
     4261 ggctcgcgct aaagtccgtg ctgagcttac aaaatacaat attagcatga ctgacaaaga
     4321 cttagacacc ttcgtagagt cagcagtgaa gcagatgaat gacgcatgga aaggacgata
     4381 gggaatggat atcgatagaa acagactacg tacaggcttg ccacaggttg gggtgcagcc
     4441 ttatcgacaa gtacatgctc actcaacagg taaccgcaac tcaaccgtac agaatgaagc
     4501 ggattatcac tggcggaaag acccagaatt aggttttttc tcgcacgttg ttgggaacgg
     4561 ttgcatcatg caggtaggac ctgtgaacaa cggaagttgg gatgttgggg gcggttggaa
     4621 tgctgagacc tatgcagcgg ttgaactgat tgaaagccat tcaactaagg aagagtttat
     4681 ggctgactat cgcctctata tcgaactctt acgcaatcta gcggacgaag caggcttacc
     4741 gaagactctt gatacagacg acttggcagg tatcaagacg catgaatact gtaccaataa
     4801 ccaaccaaac aaccactcag accatgtgga tccatatcca tatcttgcaa gttggggcat
     4861 tagccgtgaa cagtttaagc aagacatcga aaacggcttg agagctgcaa caggctggca
     4921 gaaaaatggc actggctact ggtacgtaca ctcagacggc tcttatccaa aagataagtt
     4981 tgagaaaatc aacggtacct ggtattattt cgatggctca ggctatatgc tttcagaccg
     5041 ctggaagaag tacacagacg gcaattggta ctggttcgac aactcaggcg aaatggccac
     5101 aggctggaag aaaatcgctg acaagtggta ctattttgat gtagaaggtg ccatgaagac
     5161 aggctgggtc aagtacaagg acacttggta ctacttagac gctaaagaag gcgccatggt
     5221 atcaaatgcc tttatccagt cagcagacgg aacaggctgg tactacctca aaccagacgg
     5281 aacactggca gacaagccag agttcacagt agagccagat ggcttgatta cagttaaata
     5341 aatagaaagg aaactttcta aattgttctt tcaccgcagg ctcaggcttg cggtttttta
     5401 tttgctctga ttcttcaaaa aatcgtttac atgaagaata gggaggagga atggaagagc
     5461 attattgtca aaaatgccat tttgttaata atagctcctt tttatttttt gattattgtc
     5521 aaaaacggtg ttttgtcaaa aataaaaaca gtgaccgaaa tcactgctta tcagttgtag
     5581 caaattcata aagtttttct gctgtgagaa gtgccatttt gtccatgctt gtttttcctt
     5641 ttctgaggtc agaaacagta gtccatggaa ctccagcacc ttgggaaata gcagatgtag
     5701 acatcgaact gtctaacaat tcttgaataa cttctctcat cttatttgtc ctttttattt
     5761 tttagataaa tatatacatt gattgcaatt ataaaaatag ctattgcact aaccattgca
     5821 tttcctcttt ccatttgata aaatagaggt gtaaggggct ttcgccccaa cctcttagcg
     5881 tttacctttt tctttgacgg gatttcggtt tacgcttttt gttttgcctt gcgaccgtta
     5941 ttgcggtcac tagacttgcg atagcagtta ccgtttcagg aatattgtct attgcctttt
     6001 caagtaacct gagccaatct tctttgttca acttcatcac cccctttcct tatcttgatt
     6061 atattatatc acggtacacc gagaaagtca agcgttttga tgaagttttt ttaatttttt
     6121 caaaaaaaaa tagaccttgt ccagaggtcg gggagttgga gggggcaccc tccaaaagca
     6181 ttgatttaat aagattttat ttta
//
LOCUS       DAVDHC010000063         5604 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVDHC010000063 DAVDHC010000000
VERSION     DAVDHC010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.063"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            82..1413
                     /locus_tag="VUR43_002184"
     CDS             82..1413
                     /locus_tag="VUR43_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413803.1"
                     /translation="MAYADNATGGGFSQTNTDKAFVGVYIDFNPTDSRNPADYRWTRW
                     KGRDGANGVAGKAGADGRTPYVHFAYSENADGSGLTMTDNGQRYFGHYSDYEKPDSSD
                     KTKYKWADRWAKVDGGYVNIYALSKNRSIGKSSHVSEFNMDVLSGNITLKAIGSDPYI
                     GAVSSHPGIFIKQQGMKIPVIQGRSICITITNPLFRKNYISFFNSLGKTVKTYKHYNT
                     NKFLISSADLAGVEFIALRYGAGSSNIQIGTVLETKVKVEYGTVHSDWSPAPEDIESN
                     INSKADQGLTQEQLNALNEKSQILEAEMKAKASMEAFSELEKAYNAFVKLNADSQKKS
                     ESDLVEAGRRIDLLTTQFGGLAELKTFIDTYMKSTNEGLIIGKNDASSTIKVSSDRIS
                     MFSAGKEVMYISQGVINIDNGIFTASIQIGRFRTEQYHLNKDVNVIRYIGG"
     gene            1425..3503
                     /locus_tag="VUR43_002185"
     CDS             1425..3503
                     /locus_tag="VUR43_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="structural protein"
                     /protein_id="HET5413804.1"
                     /translation="MTKFINSSGSLHLNIYIEQVSQDIANNSSRVSWKATVDRDGAYR
                     TYTYGNISNLSVWLNGSSVHSSHPNFDTSGQEFTLASGEVTIPHSGDGTKTFAVWASF
                     DPNNGVHGNITVSANYTLSSIPRSSSVSDNALSGNRRLGSPHTLTIDRKSSSFTHQVW
                     YRVFGSNWIDLGKNHATGVSFVPNIDLARYNTKAKSGTMDICVRTYNGTTQVGNDVYS
                     NGWYFEIPESVKPTFSGITLTDMNTVARQLLSGNNFLQIISDIQVNFNNPSGAYGSTI
                     TGYRAEIVNKNQVTTVNGGRLGMMNFNGSATIRASVVDSRGRQSDTRDITINVIEYFA
                     PAFSFTAFRTRETPNIIQVVRNAKIAPITLSGSQKNVMTLSFKVARLGSTTFTADRGR
                     ASGIWTTQHTLNNSAANMAGNYVATKSFVVIGTLSDKFTSTEFTATVATESVVMSYDK
                     DGRVGIGKVAEQGGAGSLDVLGDIYARNKPIQQYQLTDNNGCGKLIKQDFNTMKETGT
                     WWINGSSQNNPFSGTWGMLEVFRPNPGSHERIQRFTTSTGYMAVRENGFDNNWRPWRY
                     LVQQSKSTNNSDYVALLKSESTPTPWQNAILQNGWNHHRDYGGVQFSKTFDGVVCFKG
                     TCKGGKIARESIILTLPEHFRPSTTLFKTALNNDYGSAVIGIYPNGNVVVKSNVDATW
                     LNFDNVFFKI"
     gene            3563..3826
                     /locus_tag="VUR43_002186"
     CDS             3563..3826
                     /locus_tag="VUR43_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413805.1"
                     /translation="MLKVTKTRQLVTEFFAQDGDQQKLVKTTVINTDNKAVSTISETL
                     HDPELYANNRISMRKHEQELREMRYKIEDAILAELEADSEHKE"
     gene            3836..4252
                     /locus_tag="VUR43_002187"
     CDS             3836..4252
                     /locus_tag="VUR43_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET5413806.1"
                     /translation="MKIEFFNFLRSVVQTEDGLVLYALTLIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSICLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            4256..4591
                     /locus_tag="VUR43_002188"
     CDS             4256..4591
                     /locus_tag="VUR43_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET5413807.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRAVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVTSETGFKGDEKLEQARAKVRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            4591..5547
                     /locus_tag="VUR43_002189"
     CDS             4591..5547
                     /locus_tag="VUR43_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5413808.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHYR
                     KDPELGFFSHVVGNGRVLQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLEGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLAD
                     RWKKHTDGNWYYFDQSGEMATGWKKIADKWYYFDVEGAMQTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
BASE COUNT         1832 a         1005 c         1243 g         1524 t
ORIGIN      
        1 ttacaaggct tgcaaggcgc acgaggtgaa caaggtattc ctggacctag aggggcagat
       61 ggtcgtacac aatatactca catggcctat gccgataacg caacaggtgg tggattcagt
      121 caaacaaaca ctgacaaagc ctttgttggg gtgtacattg actttaatcc aacagacagc
      181 agaaatcctg ctgattatcg ctggacaaga tggaaaggtc gtgatggcgc aaacggcgtg
      241 gcaggtaagg ctggtgcaga tggtaggaca ccttatgttc actttgcgta ttctgaaaat
      301 gcagatggat caggtttgac aatgacagat aacggacagc gttattttgg tcattattca
      361 gattatgaga aacctgatag ttcggataaa actaagtaca aatgggctga tcgttgggct
      421 aaagttgatg gaggttatgt aaatatctat gcattgtcta agaatagaag tattgggaaa
      481 tcttctcatg tttctgaatt taatatggat gtactttcag gaaatatcac tctaaaagca
      541 attgggtcag atccatacat tggcgccgtt tcttctcatc caggtatttt tataaagcaa
      601 cagggaatga aaatcccagt tatacaaggg agatctattt gtataacaat aacaaatcct
      661 ttatttagaa aaaattacat ctcgtttttt aattcattag gtaaaactgt taaaacatat
      721 aagcattaca acacaaataa atttttaata tcttcagctg atttggcagg tgttgaattt
      781 atcgctttac gatatggtgc aggaagctcg aatatacaaa ttggaaccgt actagagaca
      841 aaagtaaagg tagaatatgg aaccgtgcat agcgactggt cgcccgctcc agaagatatt
      901 gaaagtaata ttaactctaa agctgatcag gggctgactc aagagcagtt aaatgccctc
      961 aatgagaagt cacagatttt agaggctgaa atgaaagcga aagcatcgat ggaggccttt
     1021 agtgaattag aaaaagcata taatgccttt gtgaaattaa atgcagatag tcaaaaaaaa
     1081 tctgagtctg atttagttga agcaggtaga agaattgatt tgctgacgac acaatttgga
     1141 ggattagcag agcttaaaac attcattgat acttatatga aaagcacaaa tgagggcttg
     1201 attataggta agaatgatgc aagctctact attaaggtat caagtgatag aatatccatg
     1261 ttttctgcag gtaaggaagt tatgtacatt tcgcaaggtg taataaatat tgataatggt
     1321 atttttactg catcaattca aattggacgt tttagaacag aacagtatca tcttaacaaa
     1381 gatgtgaatg tcatacgata tataggaggt taaaaaagag ggaaatgact aaatttatca
     1441 attctagcgg ttcactacac ttgaatattt acatcgaaca agttagtcaa gatatcgcta
     1501 acaattcctc aagagttagt tggaaagcta ctgttgaccg tgatggagct taccgcacat
     1561 atacttatgg taatattagt aacttgtctg tatggttaaa tgggtcaagt gtgcatagta
     1621 gtcatccaaa ctttgacaca tccgggcaag agtttacttt agcaagtggg gaagtaacca
     1681 tcccacacag tggtgacgga actaagactt ttgcagtatg ggcatcgttt gacccaaaca
     1741 acggagtaca tggaaacatt accgtgtcag caaactatac tctttcaagc attcctcgat
     1801 ctagtagtgt aagcgacaat gctctttcag gaaataggcg gctcggaagt ccccacactc
     1861 tcactattga tcgcaaatct agctcattta ctcaccaagt atggtataga gtgtttggta
     1921 gcaactggat tgatttagga aaaaatcacg caacaggcgt ttctttcgta cctaatattg
     1981 acctagctag atacaacaca aaagcaaagt ctggcacgat ggacatatgt gttcgaacat
     2041 ataatggaac tactcaagtt ggaaatgacg tttactcaaa tgggtggtat tttgaaattc
     2101 cggaaagcgt aaaacctaca ttttctggaa ttacattgac tgatatgaat actgttgcta
     2161 ggcaactatt gagcggaaat aactttttac agattatttc cgacattcag gtcaacttta
     2221 ataatccatc cggggcttat ggttcgacta tcacaggata tcgtgctgaa atcgtaaaca
     2281 agaatcaggt tacaactgta aacggtggta ggcttggtat gatgaatttc aatggttcag
     2341 caacgattcg agctagtgtg gttgatagcc gaggcaggca atcagatact agagatatta
     2401 caatcaatgt tattgaatat tttgcaccag cttttagttt tacagctttt aggacgcggg
     2461 aaacacctaa cattattcaa gttgtcagga atgctaaaat cgctcctatc actttatcag
     2521 gtagtcaaaa aaatgtcatg acactatcat tcaaagtagc tcgattaggt agtacaactt
     2581 ttacagctga tcgtggtaga gcttctggta tttggacaac tcaacacacc ttaaataatt
     2641 cagctgctaa catggcaggt aattatgttg caaccaaatc atttgtggtc ataggaactc
     2701 tatctgataa gtttacaagc acagaattta cagcaacagt tgcaactgaa agtgtggtaa
     2761 tgagttatga caaagatggc cgtgtgggca ttggtaaagt tgcagagcaa ggtggtgcag
     2821 ggtcattgga tgtcttggga gatatctacg ctagaaataa acctattcaa caatatcaat
     2881 tgactgacaa taatggatgt ggaaaactta tcaaacagga ttttaatacg atgaaagaga
     2941 ctggaacgtg gtggataaat ggtagctctc aaaacaaccc cttttctgga acttggggga
     3001 tgctagaggt attcagacct aatccaggct ctcatgaacg tattcaacgc ttcactacct
     3061 caacaggata tatggcagtt agggagaatg gttttgataa caactggaga ccatggcgct
     3121 atctggtgca acaatccaag tctactaata actctgacta tgtagctttg ctaaaatcag
     3181 aaagcactcc gactccttgg caaaatgcca ttttacaaaa tggatggaat catcacaggg
     3241 attacggagg tgtccaattt tcaaaaacat tcgatggtgt tgtttgtttt aaaggaacat
     3301 gtaagggcgg aaagattgca cgtgagtcaa tcatacttac tttacctgaa catttcagac
     3361 catctacaac attattcaaa actgctttga ataatgatta cggttcagcc gttataggaa
     3421 tttatccaaa tggaaacgta gttgtcaaat ctaatgtaga tgctacttgg cttaattttg
     3481 ataatgtgtt tttcaaaata taacaaccgt aaaaaatccc taattattaa cggataatta
     3541 atttataaag gaggaaatga caatgttaaa agtcactaaa acacgtcagc tagtaactga
     3601 atttttcgca caagatggcg accaacaaaa attggtcaaa actactgtaa tcaacacaga
     3661 caataaagct gtttcaacaa tatctgaaac gctgcatgac ccggaactgt acgctaacaa
     3721 tcgtatcagt atgcgtaagc atgagcaaga gttacgagaa atgcgctata agattgaaga
     3781 tgccattttg gcagagctgg aagcagattc tgagcataag gaataggagg tgtgtatgaa
     3841 aattgaattt ttcaattttc taagaagtgt cgtacagact gaagatggtt tggtcttgta
     3901 cgctctaaca ctgattgtct caatggaaat cattgatttt gtcacaggga cgattgcggc
     3961 gattatcaat cctgacatcg agtacaagag caaaatcggc attaacgggc tccttcgtaa
     4021 gatttcaggg gttctcttac tgatgatcct cattccggcg tccgttttgt tgcctgaaaa
     4081 gacaggtttt gtattcttgc attcaatctg tctcgggtac atcgcattta cttttcaatc
     4141 tctcattgaa aattaccgca aattaaaagg aaatgttact ctttttcagc cgattgtaaa
     4201 agtatttcag cgattacttg aaaaagatga tgatacgaaa aaaggagaat aacaaatgca
     4261 acaaattact gaaatcatta ctaatggagc aatcagcatc ctagtcattt tggcaggggt
     4321 ggtagttagg gcagtcaagg aatacctcgt caaaaaaggt ggagaaaaga ctatcaagat
     4381 tgttgaaatc ttggccaaga acgcagtaaa tgccgttgag caggttacct cagagactgg
     4441 ctttaaaggc gatgaaaagc tggagcaggc tcgcgctaaa gtccgtgctg agcttacaaa
     4501 atacaatatt agcatgactg acaaagactt agacaccttc gtagagtccg cagtgaaaca
     4561 gatgaacgac gcttggaaag gacaagagta atggatatcg atacaagcag actacgtaca
     4621 ggcttgcccc aggttggggt gcagccttat cgacaagtac atgctcactc aacaggtaac
     4681 cgcaactcaa ccgtacagaa tgaagcggat tatcactata gaaaggaccc tgaactaggg
     4741 ttcttctctc atgtggttgg aaatggtcgt gtcctgcagg tcggacctgt gaacaacgga
     4801 agttgggatg ttgggggcgg ttggaatgct gagagttatg cagcggttga actgattgaa
     4861 agccattcaa ctaaggaaga gtttatggct gactatcgcc tctatatcga attgctacgc
     4921 aatctagcgg acgaagcagg cttgccgaag actcttgata cagacgactt ggaaggtatc
     4981 aagacgcatg aatactgtac caataaccaa ccaaacaacc actcagacca tgtggatcca
     5041 tatccatatc ttgcaagttg gggcattagc cgtgaacagt ttaagcaaga catcgaaaac
     5101 ggcttgagcg ctgcaacagg ctggcagaaa aatggcactg gctactggta cgtacactca
     5161 gacggctctt atccaaaaga taagtttgag aaaatcaacg gtacctggta ttatttcgat
     5221 ggctcaggct atatgcttgc agaccgctgg aagaagcaca cagacggtaa ttggtactac
     5281 tttgaccaat caggcgaaat ggccacaggc tggaagaaaa tcgctgacaa gtggtactat
     5341 ttcgacgtag aaggtgctat gcaaacaggt tgggtcaagt acaaggacac ttggtactac
     5401 ttagacgcta aagaaggtgc tatggtatca aatgccttta tccagtcagc ggacggaaca
     5461 ggctggtact acctcaaacc agacggaaca ctggcagaca agccagagtt cacagtagag
     5521 ccagatggct tgattacagt taaataaata gaaaggaaac tttctaaatt gttctttcac
     5581 cgcaggctca ggcttgcggt tttt
//
LOCUS       DAVDHC010000064         5130 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVDHC010000064 DAVDHC010000000
VERSION     DAVDHC010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.065"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            65..508
                     /locus_tag="VUR43_002190"
     CDS             65..508
                     /locus_tag="VUR43_002190"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET5413809.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            510..1025
                     /locus_tag="VUR43_002191"
     CDS             510..1025
                     /locus_tag="VUR43_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET5413810.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATSLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            1039..2400
                     /gene="radA"
                     /locus_tag="VUR43_002192"
     CDS             1039..2400
                     /gene="radA"
                     /locus_tag="VUR43_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET5413811.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            2473..2970
                     /locus_tag="VUR43_002193"
     CDS             2473..2970
                     /locus_tag="VUR43_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET5413812.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            2995..3204
                     /locus_tag="VUR43_002194"
     CDS             2995..3204
                     /locus_tag="VUR43_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413813.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            3186..3809
                     /locus_tag="VUR43_002195"
     CDS             3186..3809
                     /locus_tag="VUR43_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET5413814.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIKDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            3954..4922
                     /locus_tag="VUR43_002196"
     CDS             3954..4922
                     /locus_tag="VUR43_002196"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET5413815.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
BASE COUNT         1394 a          891 c         1260 g         1585 t
ORIGIN      
        1 gtgctttttc cgaataaata agatagaata atctagaata aatgataata gaaaagagaa
       61 aattatgaaa attcgtggtt ttgaattggt ttcgagtttt acagatgaaa atttattgcc
      121 caagcgtgag acagcgcatg cggctggtta cgacttaaag gttgctgtgc gtacagttgt
      181 tgcgccagga gagattgtct tggttccgac aggggttaag gcttatatgc agccgactga
      241 ggttctctac ctctatgatc gttcttcaaa tcctcgtaag aagggcttgg ttttaattaa
      301 ctcagttggg gtcattgatg gggattatta tggaaatcct ggaaatgaag ggcatatttt
      361 tgcgcagatg aagaatatca cagaccaaga ggttgttctt gaagttgggg aacgtattgt
      421 ccaggctgtt tttgctactt tcttaattgc agatggagat gcagctgatg gcgttcgaac
      481 tggtggattt ggatcgacag ggcactagaa tgaagattat ctttgtacgt catggggagc
      541 cagattaccg tgagttagag gagcgttctt atataggatt tgggatagat ttggcaccct
      601 tgtctgagat gggacggcag caagtccaga aattgagcaa aaatccttta ctctcgtcag
      661 ctgaaataat cgtatcttct gcagtcacaa gagctttaga aacggcttcg tatgtggtct
      721 gtgctacgag tcttccttta agagtagagc ctttattaca tgaatggcag gtctataaaa
      781 caggaataga aaactttgaa acagctagaa gactgttttt agaaaacaag ggggagttgc
      841 ttcctaatag tcctattcaa tatgagacag ctacggaaat gaagtctcgg tttctagaat
      901 gtatgtctaa gtatcgagaa catcagactg tggtagttgt tgctcatcga atgctcatgc
      961 gccagtttgt gccaaatgag aagattgatt tttgccaagt gattgagtgt gagttagaga
     1021 tatagaaaga ggtttgtcat cgcaaagaaa aaagcgacat ttgtatgtca aaattgtggg
     1081 tataattccc ctaaatatct gggacgttgc cccaactgtg ggtcttggtc ttcttttgtg
     1141 gaagaggttg aggttgccga ggtcaagaat gcgcgtgtgt ccttgacagg tgagaaaacc
     1201 aagcccatga aactagctga ggtgacttcc atcaatgtca atcgaaccaa gacggagatg
     1261 gaggaattca accgtgtgct tggaggcgga gtggtaccag gaagtctcgt cctcatcggt
     1321 ggggatcctg ggattgggaa atcaactctt ctcctacaag tctcaaccca gttgtcccaa
     1381 gtggggacag ttctctatgt cagtggggag gagtctgccc agcagattaa actacgtgca
     1441 gagcgcttag gtgatattga tagtgagttt tatctctatg cagagaccaa tatgcagagt
     1501 gttcgtgcag aagtggagcg tatccagcca gactttctca ttattgattc catccagacc
     1561 atcatgtctc ctgagatttc aggggtgcag gggtctgttt ctcaggtacg tgaagtgacc
     1621 gctgaactca tgcagttggc caagaccaat aacattgcca tctttatcgt aggtcatgtg
     1681 accaaagaag gaaccttggc tgggcctcgt atgttggagc atatggtgga tacggtgctt
     1741 tactttgaag gggagcgtca ccacaccttt cgtattttga gagcggtcaa aaatcgtttt
     1801 ggttccacta atgagattgg gatttttgag atgcagtcgg gcggcttggt tgaggtactc
     1861 aatccgagtc aagttttcct agaagagcgt ttggatgggg cgactggttc ctccatcgtt
     1921 gtaaccatgg aagggacgcg tccgattttg gcggaggttc aggctttggt aacaccgacc
     1981 atgtttggaa atgccaagcg tactacgaca ggacttgatt ttaaccgtgc tagcttgatt
     2041 atggctgttt tggaaaaacg ggcagggctt ctcttgcaaa atcaggatgc ctatctcaaa
     2101 tctgctggtg gtgttaaatt ggatgaacct gccattgact tggctgttgc agttgctatt
     2161 gcttcgagct acaaagacaa gccaactaat cctcaggaat gttttgtcgg agaactgggc
     2221 ttgacaggag agattcggcg cgtgaatcgt attgagcaac gcatcaacga agctgctaaa
     2281 ctgggcttta ctaagattta tgtacctaag aattccttga caggaatcac tctgcctaag
     2341 gaaattcagg tcattggcgt gacaacgatt caggaagtct tgaaaaaggt ctttgcataa
     2401 tccgtgacaa attctcttaa aaatgataag ataggagaaa tatttgacta tcaaattttc
     2461 aaggagggaa tcgtgtcgta ttttgaacag tttatgcaag ccaatcaggc ttatgttgcc
     2521 ctacatgggc agttaaatct gccacttaaa cctaaaacca gagtagccat tgtgacctgt
     2581 atggactcac gtttgcacgt tgcgcaagct ctaggtttgg cacttgggga tgctcatatc
     2641 ttgcggaatg caggtggtcg agtgactgaa gacatgattc gttcgctagt tatttcccag
     2701 caacaaatgg ggacaagaga gattgtggta ttgcaccata cagactgtgg tgctcagacc
     2761 tttgaaaatg aaccttttca ggagtattta aaagaggaat taggtgtaga tgtgtcagac
     2821 caggacttct tgcccttcca agatatagaa gagagtgtac gcgaggatat gcaactgctt
     2881 atcgagtctc ccctaatacc agacgatgtc attatctctg gtgccattta caatgttgat
     2941 acaggaagta tgacagtcgt agaattataa atacttcatt tagaaagaaa gtgtatgaag
     3001 aaaagcagta ttttatttat ttttatttta ttgctatgta ttggtttaca gtatgaaacc
     3061 atctactata cggacggttc gaggtcaggt gcggaatatg gactaatggg agtttctatc
     3121 tttctagctc tcttttacat gattccggct ctttattttc tcttccgtat tgggaaaaat
     3181 gggaattgcc aaagaaggtt ttgattctgt ctttattggg agggatgttc ctttcaggct
     3241 ggttgtctag ttttgctaat acttatatcc atgatttact gggggttctt ttcccagata
     3301 gtacattttt aaatgccttt gaaagtgcta ttgtggctcc tttggtagaa gaacccttga
     3361 aattattgcc acttgttttt gttttggctt tgattcctgt gcgaaaatta aaatctttgt
     3421 ttttacttgg aattgcttcc ggtttgggat tccaaatgat taaggatatt ggttatattc
     3481 gtacggattt gccagagggc tttgatttta ctatttcgcg aattttagag cgtatcatct
     3541 caggaattgc ctctcactgg actttttcag gtctagctgt agtaggtgtt tacttgcttt
     3601 acagagccta taaaggacag aaggttggca agaaacaggg ccttattttt ctaggtttag
     3661 ccttgggaac tcacttcttg tttaactctc cttttgtgga gttggaaaca gagttgcctt
     3721 tagcgattcc agtggttacg gctattgctc tctatggttt ttatcatgct tattgctttg
     3781 ttgagaaaca caatgagttg atgacctaga atatttttca aaagaatgat gcaaggatac
     3841 aaatatggtg cccttctttt atttttgatt gaaaaatagt gcaaaaagcg ctacaatggt
     3901 agatggaaaa tcttgtgaaa agcacaagtt atacatatat accggaggaa atcatgtctt
     3961 tttctgattt aaagctgttt gccctttctt ctaataaaga attggcagaa cgtgtggcgc
     4021 aggagattgg gatagagttg gggaaatcaa gtgttcgcca attttcagat ggagagattc
     4081 aggtcaacat tgaagaatca atccgtggga aacacgtctt tatcctacaa tcaactagtt
     4141 cgcctgtaaa tgacaatctg cttgaaattt tgattatggt agatgctttg aagcgtgcga
     4201 gtgcagaatc tgtcaatgtt gtcatgcctt actatgggta tgcacgtcag gatagaaagg
     4261 cgagagcgcg tgagccaatc acttcaaaac ttgtcgcaaa tatgcttgaa gtagctggag
     4321 tggatcgttt attgaccatc gacttgcatg ctgcgcaaat tcaaggattc tttgatattc
     4381 ctgtggatca tttgatgggt gctcctctga ttgcagatta ttttgagcgt cgtggtatgg
     4441 ttggttctga ctatgtggtt gtcagcccgg accatggagg ggtgactcgt gctcgtaagt
     4501 tggcagaatt tttgaaaaca tctatcgcta ttattgataa acgtcgtagc gttgataaga
     4561 tgaatactag tgaagttatg aacatcatcg gtaaggttga aggcaagact tgtatcttga
     4621 ttgatgatat gattgatacc gctggaacga tttgtcatgc ggcagatgct cttgcggaag
     4681 ctggtgctgt tgaagtctat gcaagctgta cgcacccagt tctttctggt cctgctacgg
     4741 acaatatcca aaaatcagct attaagaaat tggttgtttt ggataccatc tatcttccag
     4801 aagagcgttt gattgataag attgagcaga tttcaatcgc tcatctccta ggggatgcta
     4861 tcgtacgtat tcatgaaaaa cgaccacttt ctccactttt cgatattgag aaaaaaattt
     4921 aatgaccaag cctgagatga ttctcaggtt ttttcgtctt ttttccgaat aaatagatag
     4981 tagcggtgaa tctagtaaag ctagatttaa aactgtgata taataaaaag agaagaaata
     5041 tgactgtacg tcatcagaag tttcagcgac catcattttt gaacagtgat agcacttgaa
     5101 tcgacgcttt ctaaggagaa ttctagtagg
//
LOCUS       DAVDHC010000065         4859 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVDHC010000065 DAVDHC010000000
VERSION     DAVDHC010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4859
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.066"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..1537
                     /locus_tag="VUR43_002197"
     rRNA            <1..1537
                     /locus_tag="VUR43_002197"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1589..1661
                     /locus_tag="VUR43_002198"
     tRNA            1589..1661
                     /locus_tag="VUR43_002198"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1622..1624,aa:Ala,seq:tgc)
     gene            1786..4687
                     /locus_tag="VUR43_002199"
     rRNA            1786..4687
                     /locus_tag="VUR43_002199"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            4764..>4859
                     /gene="rrf"
                     /locus_tag="VUR43_002200"
     rRNA            4764..>4859
                     /gene="rrf"
                     /locus_tag="VUR43_002200"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1342 a         1000 c         1445 g         1072 t
ORIGIN      
        1 agtttgatcc tggctcagga cgaacgctgg cggcgtgcct aatacatgca agtagaacgc
       61 tgaaggagga gcttgcttct ctggatgagt tgcgaacggg tgagtaacgc gtaggtaacc
      121 tgcctggtag cgggggataa ctattggaaa cgatagctaa taccgcataa gagtggatgt
      181 tgcatgacat ttgcttaaaa ggtgcacttg catcactacc agatggacct gcgttgtatt
      241 agctagttgg tggggtaacg gctcaccaag gcgacgatac atagccgacc tgagagggtg
      301 atcggccaca ctgggactga gacacggccc agactcctac gggaggcagc agtagggaat
      361 cttcggcaat ggacggaagt ctgaccgagc aacgccgcgt gagtgaagaa ggttttcgga
      421 tcgtaaagct ctgttgtaag agaagaacga gtgtgagagt ggaaagttca cactgtgacg
      481 gtatcttacc agaaagggac ggctaactac gtgccagcag ccgcggtaat acgtaggtcc
      541 cgagcgttgt ccggatttat tgggcgtaaa gcgagcgcag gcggttagat aagtctgaag
      601 ttaaaggctg tggcttaacc atagtaggct ttggaaactg tttaacttga gtgcaagagg
      661 ggagagtgga attccatgtg tagcggtgaa atgcgtagat atatggagga acaccggtgg
      721 cgaaagcggc tctctggctt gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag
      781 gattagatac cctggtagtc cacgctgtaa acgatgagtg ctaggtgtta gaccctttcc
      841 ggggtttagt gccgtagcta acgcattaag cactccgcct ggggagtacg accgcaaggt
      901 tgaaactcaa aggaattgac gggggcccgc acaagcggtg gagcatgtgg tttaattcga
      961 agcaacgcga agaaccttac caggtcttga catccctctg accgctctag agatagagct
     1021 ttccttcggg acagaggtga caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg
     1081 ttgggttaag tcccgcaacg agcgcaaccc ctattgttag ttgccatcat ttagttgggc
     1141 actctagcga gactgccggt aataaaccgg aggaaggtgg ggatgacgtc aaatcatcat
     1201 gccccttatg acctgggcta cacacgtgct acaatggctg gtacaacgag tcgcaagccg
     1261 gtgacggcaa gctaatctct taaagccagt ctcagttcgg attgtaggct gcaactcgcc
     1321 tacatgaagt cggaatcgct agtaatcgcg gatcagcacg ccgcggtgaa tacgttcccg
     1381 ggccttgtac acaccgcccg tcacaccacg agagtttgta acacccgaag tcggtgaggt
     1441 aaccgtaagg agccagccgc ctaaggtggg atagatgatt ggggtgaagt cgtaacaagg
     1501 tagccgtatc ggaaggtgcg gctggatcac ctcctttcta aggataagga actgcgcatt
     1561 ggtcttgttt agtcttgaga ggtcttgtgg ggccttagct cagctgggag agcgcctgct
     1621 ttgcacgcag gaggtcagcg gttcgatccc gctaggctcc attggtgaga gatcaccaag
     1681 taatgcacat tgaaaattga atatctatat caaatagtaa caagaaaata aaccgaaaac
     1741 gctgtagtat taataagagt ttatgactga aaggtcagaa aataaggtta agttaataag
     1801 ggcgcacggt ggatgccttg gcactaggag ccgacgaagg acgtgacaaa cgacgatatg
     1861 ccttgggtag ctgtaagtaa gcgatgatcc agggatttcc gaatggggga acccaacagg
     1921 tagtacctgt tacccacatc tgttaaggat gtgaggagga agacgcagtg aactgaaaca
     1981 tctaagtagc tgcaggaaga gaaagcaaaa gcgattgcct tagtagcggc gagcgaaacg
     2041 gcaggagggc aaaccgaaga gtttactctt cggggttgta ggactgcaat gtggactcaa
     2101 agattataga agaatgattt gggaagatca gccaaagaga gtaatagcct cgtatttaaa
     2161 atagtctttg tacctagcag tatcctgagt acggcgggac acgtgaaatc ccgtcggaat
     2221 ctgggaggac catctcccaa ccctaaatac tccctagtga ccgatagtga accagtaccg
     2281 tgagggaaag gtgaaaagca ccccgggagg ggagtgaaat agaacctgaa accgtgtgcc
     2341 tacaacaagt tcgagcccgt taatgggtga gagcgtgcct tttgtagaat gaaccggcga
     2401 gttacgttat gatgcgaggt taagttgaag agacggagcc gtagggaaac cgagtctgaa
     2461 tagggcgcct tagtatcatg acgtagaccc gaaaccatgt gacctaccca tgagcaggtt
     2521 gaaggtgcgg taagacgcac tggaggaccg aaccagggca cgttgaaaag tgcttggatg
     2581 acttgtgggt agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata
     2641 gctttagggc tagcgtcgac attagagatt cttggaggta gagcactgtt tgggtgaggg
     2701 gtccatcccg gattaccaat ctcagataaa ctccgaatgc caatgaatta tggtcggcag
     2761 tcagactgcg agtgctaaga tccgtagtcg aaagggaaac agcccagacc accagctaag
     2821 gtcccaaaat aattgttaag tggaaaagga tgtggggttg cacagacaac taggatgtta
     2881 gcttagaagc agctattcat tcaaagagtg cgtaatagct cactagtcga gtgaccctgc
     2941 gccgaaaatg taccggggct aaaacaattt accgaagctg tggatacctt tataggtatg
     3001 gtaggagagc gttctatgtg tgatgaaggt ataccgtgag gagtgctgga acgcatagaa
     3061 gtgagaatgc cggtatgagt agcgaaagac aggtgagaat cctgtccacc gtaagactaa
     3121 ggtttccagg ggaaggctcg tccgccctgg gttagtcggg acctaaggag agaccgaaag
     3181 gtgtatccga tggacaacag gttgatattc ctgtactaga gtatgtagtg atggagggac
     3241 gcagtaggct aactaaagca gacgattgga agagtctgtc taagcagtga ggtgtgaatt
     3301 gagtcaaatg cttaattcta taacattgag ctgtgatggg gagcgaagtt tagtagcgaa
     3361 gttagtgacg tcacactgcc aagaaaagct tctagcgttt aaacatactc tacccgtacc
     3421 gcaaaccgac acaggtagtc gaggcgagta gcctcaggtg agcgagagaa ctctcgttaa
     3481 ggaactcggc aaaatgaccc cgtaacttcg ggagaagggg tgctgactta aagtcagccg
     3541 cagtgaatag gcccaagcaa ctgtttatca aaaacacagc tctctgctaa atcgtaagat
     3601 gatgtatagg gggtgacgcc tgcccggtgc tggaaggtta agaggagtgc ttagcgtaag
     3661 cgaaggtatg aattgaagcc ccagtaaacg gcggccgtaa ctataacggt cctaaggtag
     3721 cgaaattcct tgtcgggtaa gttccgaccc gcacgaaagg cgtaatgatt tgggcactgt
     3781 ctcaacgaga gactcggtga aattttagta cctgtgaaga tgcaggttac ccgcgacagg
     3841 acggaaagac cccatggagc tttactgcag tttgatattg agtgtctgta ccacatgtac
     3901 aggataggta ggagtctaag agatcgggac gccagtttcg aaggagacgc tgttgggata
     3961 ctacccttgt gttatggcca ctctaaccca gataggtgat ccctatcgga gacagtgtct
     4021 gacgggcagt ttgactgggg cggtcgcctc ctaaaaggta acggaggcgc ccaaaggttc
     4081 cctcagaatg gttggaaatc attcgcagag tgtaaaggta taagggagct tgactgcgag
     4141 agctacaact cgagcaggga cgaaagtcgg gcttagtgat ccggtggttc cgtatggaag
     4201 ggccatcgct caacggataa aagctaccct ggggataaca ggcttatctc ccccaagagt
     4261 tcacatcgac ggggaggttt ggcacctcga tgtcggctcg tcgcatcctg gggctgtagt
     4321 cggtcccaag ggttgggctg ttcgcccatt aaagcggcac gcgagctggg ttcagaacgt
     4381 cgtgagacag ttcggtccct atccgtcgcg ggcgtaggaa atttgagagg atctgctcct
     4441 agtacgagag gaccagagtg gacttaccgc tggtgtacca gttgtcttgc caaaggcatc
     4501 gctgggtagc tatgtaggga agggataaac gctgaaagca tctaagtgtg aaacccacct
     4561 caagatgaga tttcccatga ttatatatca gtaagagccc tgagagatga tcaggtagat
     4621 aggttagaag tggaagtgtg gcgacacatg tagcggacta atactaatag ctcgaggact
     4681 tatccaaagt aactgagaat atgaaagcga acggttttct tgaattgaat agatattcaa
     4741 ttttgagtag gtattactca gagttaagtg acgatagcct aggagataca cctgtaccca
     4801 tgccgaacac agaagttaag ccctagaacg ccggaagtag ttgggggttg ccccctgtg
//
LOCUS       DAVDHC010000066         4785 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVDHC010000066 DAVDHC010000000
VERSION     DAVDHC010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.067"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..1637)
                     /locus_tag="VUR43_002201"
     CDS             complement(<1..1637)
                     /locus_tag="VUR43_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET5413816.1"
                     /translation="MFKVLRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNGTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKL
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSEEKVYTGEGVDSVYRVPIYYKLKVTNDGSKLTFTYTVTYVNPKTNALGNISNMRSG
                     YSIYNTGTSTQTMLTLGSGLGKPSGVKNYITNKNGERVLSYNTSTMTTQGSGYTWGNG
                     AQMNGWHAKRGHGLTSSWTVSITGTDTSFTFTPYAAKTDSIRINYFNGKGKVVESSTT
                     SQSLSQSKSLSVSASQSASASESASTSASASASTSASESASTSASASASTSASVSAST
                     SASVSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSASTSA
                     STSASTSASTSASTSASTSASTSASTSASTSASTSAST"
     gene            complement(1635..1748)
                     /locus_tag="VUR43_002202"
                     /pseudo
     CDS             complement(1635..1748)
                     /locus_tag="VUR43_002202"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(1998..2459)
                     /locus_tag="VUR43_002203"
     CDS             complement(1998..2459)
                     /locus_tag="VUR43_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5413817.1"
                     /translation="MGKERREQGNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIA
                     ARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSEFLDILDNLKDLPVLYIDETGI
                     NRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLNGSFLIRYIDSQIRE"
     gene            complement(2426..2569)
                     /locus_tag="VUR43_002204"
     CDS             complement(2426..2569)
                     /locus_tag="VUR43_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5413818.1"
                     /translation="MAYSTDFKQGALDSIKEGHRYVEAAKVFDVGARTLFTWEKKDVN
                     KGT"
     gene            2835..3215
                     /locus_tag="VUR43_002205"
     CDS             2835..3215
                     /locus_tag="VUR43_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET5413819.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            3314..3535
                     /locus_tag="VUR43_002206"
     CDS             3314..3535
                     /locus_tag="VUR43_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET5413820.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            3552..3866
                     /gene="trxA"
                     /locus_tag="VUR43_002207"
     CDS             3552..3866
                     /gene="trxA"
                     /locus_tag="VUR43_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET5413821.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            4171..4704
                     /gene="queF"
                     /locus_tag="VUR43_002208"
                     /pseudo
     CDS             4171..4704
                     /gene="queF"
                     /locus_tag="VUR43_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
BASE COUNT         1396 a         1001 c          937 g         1451 t
ORIGIN      
        1 gtcgacgcgc ttgttgatgc cgatgtgctt gctgaggtcg acgcgcttgt tgatgctgac
       61 gtgcttgctg acgtacttgc gcttgttgat gctgatgtgc ttgcacttgt tgatgctgac
      121 gtgctggcac ttgttgatgc cgatgtactt gctgaggtcg acgcacttgt tgaagcggac
      181 gtacttgcac ttgttgacgc cgatgtgctt gcacttgtcg atgctgacgt gcttgccgat
      241 gtacttgctg acgtgctggc actggttgac gctgagactg aagcactcgt tgatgctgag
      301 actgaagcac ttgtgcttgc tgaagctgaa gcactcgttg atgccgattc agacgctgag
      361 gtgcttgctg aagctgaagc actcgttgat gccgattcag acgctgaggc gctttgacta
      421 gcacttactg agagtgactt agactgtgaa agtgactgac tggtcgtgct agattcaact
      481 acctttcctt taccattgaa gtagttaatt ctaatgctat ctgttttagc agcgtaaggg
      541 gtaaatgtaa aggatgtatc cgttccagta attgatacag tccaagatga tgttaatcca
      601 tgtcctctct tagcatgcca accattcatt tgggcaccat ttccccaagt atacccacta
      661 ccctgcgtcg tcattgtaga tgtattatag gatagaaccc gttcaccatt tttgttagta
      721 atgtagttct ttacacctga aggtttacca agaccactgc caagggttaa cattgtttgt
      781 gttgaagtac ctgtattata gatagaatac ccagaacgca tatttgatat attaccaaga
      841 gcatttgttt taggattcac atacgtaacc gtataggtaa aggtcaattt tgaaccatca
      901 tttgtcactt tcaatttata gtaaattgga acacgatata ccgaatctac accttcacct
      961 gtataaactt tttcctcact tttagcaatg tttagacttg cattaattgc aggggcgcca
     1021 tttacaatcg tattgccaga aaaaacagca gcttttatag aagccagcaa ttgctcgatg
     1081 gaatccactg aacgcttgcg tcgcttagca taagattgga gattgacatt tgtaactgat
     1141 gctgcataat cactagctag tttcttacga tcttcttcga ccttcttagc agttgcttct
     1201 gtagcggcag ctgtttgtga tcctaccaca gtagatgatg cagagatact tgtcgaagcc
     1261 gatgtacttg ctgattctga tgcacttgta ctcgctgagg tcgaagcgct ggttgaggct
     1321 gactcagatg cagatgtact tgccgactct gaagctgaca aactagttga actcgctgaa
     1381 ttacttgtag atatcgtacc tagaactact gtaccatttg ttgccaaagc atccgttttc
     1441 tctacagttt tttcaagtac tgctgactca tttgtaaata ccttcgtttg agttgcaacg
     1501 gttccactta tgacagttcc cgcagcaact atccccttga ggatatcaag cccagtaatt
     1561 gaatgactta ctttatcttc taccgtttcg gtcatgacct gagtagtatc aacaccacct
     1621 cgcaagacct taaacaagcc aaaaagagaa gtcgaggccc gtagccaatg cttccctgat
     1681 ttgattaatt tgaaccgagt tactcggtct gtttctctat attcaccctt ctgacgtcta
     1741 aaaaatattt tgaaatttcc tttcgagtat tattttcatg tatggatata aataaattac
     1801 catactataa ttatagaata gggaacccaa aatagcaaga aacttgaggt atttttgcta
     1861 aaaaaaaaaa gcattttact gttttgtata tatatatata tatatattat aagataagtt
     1921 ttttataaag acacgcaaat gagtataaat cagctaattt ttggtttaca ttcctatttt
     1981 tatgcataat tattctgtca ttctctaatt tgtgaatcaa tatatctgat tagaaaacta
     2041 ccattgagtt tttgctccac ctcattagtc cgctcaaaac gccgtccgct aatcttgtca
     2101 tagactttct cccctctagg agcccctgca taaggacgat agaggtagcg gttgattccc
     2161 gtttcgtcaa tatataggac tggtaaatct tttaggttat ccaaaatatc aagaaactca
     2221 gaaactttct caggcttttg ttccctaaaa ctggtcgtct tttttaaaat gaccttaatc
     2281 tgctttaaaa ctgcccatac ggagggcaaa gcacaatcaa aacgggccgc aatttcccgt
     2341 aaaaaagcgt ctggatgagc ctctacaaag gctttcaatt cttctaaagg gatcttacgc
     2401 tttttgacga ctcgcttttt cctctctaag ttcccttgtt cacgtctttc ttttcccacg
     2461 tgaagagagt tctggcgccg acatcaaaaa ctttggccgc ctcgacatat ctgtgcccct
     2521 ctttgatgga atctaatgct ccttgtttaa aatcagtact atatgccata gctttattag
     2581 accatgctta ttttaaacta agcaactata gatagagaaa tgaaataaaa tctgaattcg
     2641 aatgtgataa ggagttagaa attaaaacaa taggattccc ccattattca cacaaaataa
     2701 aatcactaaa aacagagctt gccagcattc ttgaaaagta gtataattat tgcatgcgca
     2761 atcatcttgt gacgcagaga ctgcccgtta atggactttc ttctatttat gactctaaaa
     2821 agaaaggaga cactatgacc tatttggaaa aatggtttga cttcaatcgg cgtcagaaag
     2881 aaattgaaag tctcttggaa gagaccattg cccaacagag cgagcaaagt ctgaccttga
     2941 aagagttcta cctgctctac tatctggact tggctgaaga aaaatctcta cgccagattg
     3001 acctgccaga taagcttcat ctgagcccga gcgcagtttc taggatggtg gctcgcttgg
     3061 aagctaaaaa ttgcggtcta ctcagtcgca tgtgttgcca tcaagataga cgctctagtt
     3121 ttatctgcct gacaaatgat gggcaaaaga cactggcctc gctacaaaag actgtcgaag
     3181 aaagcttgga agcaggtttg gatttcttga tttaagatga ttttagaaaa agttgcgtgc
     3241 gcaatcattt ttcttgacat tctcttttat aaggagtaaa ataaagttag cattaaacaa
     3301 aggagtttta aatatgattg aaattaccta tatagatgcc agcaagaacg aaagaactgt
     3361 gactttcgag tcttatgaag actttgaacg ttcgcaacaa gcttgcctta tcggcgtcgc
     3421 agactactac cctgtccaaa aattaactta caagggtcat aatttggact accatgggac
     3481 ttatggagat atcttcttct atctcatgaa acaagattta agccaatata actaaaaaaa
     3541 ggagaaatac aatggcaaaa gcaattacag atgcaacatt cgaacaagaa acaaaagacg
     3601 gtttggtctt agtagacttc tgggcaactt ggtgtggtcc atgtcgtatg caaggtccaa
     3661 tcttggacaa attgtctgaa gaactttcag aagatgtctt gaaaatcgtt aaaatggacg
     3721 ttgatgaaaa tccaaacaca gctcgtgctt ttggaatcat gtctattcca actcttctct
     3781 tcaaaaaaga cggccaagtt gtcaaacaag ttgcaggtgt tcacacagca gaacaaatca
     3841 aggccatcat tgctgaattg agctaatcaa acgagagacc aagtactttc tttggtctct
     3901 tttttcttgc cctttgccat ttttcaaaaa atatgctaga ctatagtaga ttgaaactag
     3961 aatagtacac ctctacttct aaaacattgt tagaaatcga tttgactgtc ctgatcaatt
     4021 tgtcctgttc ttatttcatt ttactatata agtagaatat tacgatgttt gggatatgcc
     4081 atcgctaaaa aaactcgatt tggtattttt tagctcccta atgggagctt tttgcgtgct
     4141 ctgaacattt cccattttgg aaggagtact atgaaacatc aatcagcctt ggtcgtcttt
     4201 agtggtggtc aagattcaac aacctgcctt ttctgggcca tgcaacacta tgaaacagtc
     4261 gaagctgtca cctttgccta cggccaacgt catcacctcg aaattcaaat tactagagaa
     4321 atcgctaagg aacagggcat tcgtcaccat atcctcgata tgtctctgct gggacaaatc
     4381 actgctcagc cagactttgc gacgattcat atttcctaca ttcctgacaa gctctgtgtc
     4441 gagtcaaaat ccctcaaact atatctattt agctaccgaa accacggaga tttccacgaa
     4501 aactgtatca acaccatcgg gaaagacttg gtcaacttgc tagaccctcg ctatttagaa
     4561 gtatagggaa aattcactcc gcgcggtggc atttcaatcg acccctacta caactacggt
     4621 aagcaaggaa ctaagtatga gggcttggca gaacaacgcc tcttccaaca cgacctttat
     4681 ccagagaaaa ttgacaaccg ctaaagtcat actcaatgaa aatcaaagag caaactagga
     4741 agttagccgc aggttgctca aagcagtgtt tgaggttata gataa
//
LOCUS       DAVDHC010000067         4562 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVDHC010000067 DAVDHC010000000
VERSION     DAVDHC010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4562
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.068"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..236)
                     /locus_tag="VUR43_002209"
     CDS             complement(<1..236)
                     /locus_tag="VUR43_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET5413822.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIIKKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRR"
     gene            360..602
                     /locus_tag="VUR43_002210"
                     /pseudo
     CDS             360..602
                     /locus_tag="VUR43_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(960..1493)
                     /locus_tag="VUR43_002211"
     CDS             complement(960..1493)
                     /locus_tag="VUR43_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET5413823.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(1582..2358)
                     /gene="recX"
                     /locus_tag="VUR43_002212"
     CDS             complement(1582..2358)
                     /gene="recX"
                     /locus_tag="VUR43_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET5413824.1"
                     /translation="MKITKLEKKKRLYLMELDNVDKCYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYTIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASVLREYL"
     gene            complement(2368..3144)
                     /locus_tag="VUR43_002213"
     CDS             complement(2368..3144)
                     /locus_tag="VUR43_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET5413825.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKITSWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     KLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            3201..4556
                     /gene="rlmD"
                     /locus_tag="VUR43_002214"
     CDS             3201..4556
                     /gene="rlmD"
                     /locus_tag="VUR43_002214"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET5413826.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1455 a          769 c          830 g         1508 t
ORIGIN      
        1 cgacgctttc taaggagaat tctagtaggc ataccagtcg tttcaagata aggaatttta
       61 gaaggttttt gaaagtcata tttcttcaat tggtttccgc actcagggca agatggggcg
      121 tcgtagtcca gtttggcgat gatttccttg tgtgtatcct tcttgatgat gtctaaaatc
      181 tggatattag ggtctttaat gtctagtaat tttgtgataa aatgtaattg ttccatatga
      241 atctttctaa tgagttgttt tgtcgctttt cattatagat cttatgggac tttttttcta
      301 cacaaaatag gctccataat atctatagtg gatttaccca ctacaaatat tatagagccg
      361 aaaattcaca tctaatatat gcagactact ttgaaatgaa attacaaaaa ttattaaaag
      421 atgacacaaa agtttttgaa aaatctacat tcaaatttgt agaaggatat aaaatatacc
      481 tgacagaatc taaagaatct ggaattaaac aaatggacaa tgtcataaaa tattttgagt
      541 ttattgaatc taaaagtatt gctttatatt ttcaaaaacg attaaatgag ctgatagatt
      601 aaatagcatt ttctctgttg agatattgtt tttaaaatat tgtactaaat gattgatgct
      661 atgtggaaat acaaaaaaat gtttttgata cgaagttgac ctgtattttt tatactaatc
      721 attttcgtat tttttgtatt aaacgatata agtttgttgt aaacttacaa ggaataaaga
      781 cattaaaaaa taacagtata tctatttgtt ttatatattt tacgaattct gcataaattt
      841 ctttctagta atgtgttgta actctgctat aatggattta ttcctttttg tgtttacaca
      901 atttatttta tactaccaaa aaaacaaggt caggattttg ttcctgacct ttgacaactt
      961 taccgattct ttagttctac atagcgcttg taccaaatgt ttacataggc ttctgagaaa
     1021 ggaccacgtc cattgttaat ccaatcaaca agaattttga catgttcttt taaaatatag
     1081 tccaagtcat cagaataatt cattttgcgt ttgtgacgct cgtattcttc aacgtccaag
     1141 agacgttttt ccccatctgt aaaaatttta acatccaaat cgtaatcaat atacttcagt
     1201 gcttcttcat ccagatagta ggggctagcc atattgcaat agtaagaagt tccattatca
     1261 cgaatcatgg caatgatatt aaaccaatat ttcttgtgaa agtaaacaat agccggttct
     1321 cgagtgaccc aacgacgacc atcactttcg gtaacaagtg tatgatcgtt gacaccaata
     1381 atggcgtttt ctgttgtttt tagtaccatg gtgtcccgcc aagttcggtg gagactccca
     1441 tcatgcttat aactttgaat tgtaataaag tcgccttctt ttggaagctt cataactaac
     1501 caactttcta caatttataa gtttatcatt tactattgta ccataaaatt acctaaaatc
     1561 tgtgaatttc acttggaaat attaaagata ttctctaaga acgcttgcta tatccgaaaa
     1621 atcgtagccc tttcgtgcta aaacttgagt taaacgctgc ttcagttcgt atccttcata
     1681 ctttcgggca tacttagtat attgcttatc aagttccttg aagatgagtt cctgagtcgt
     1741 ttcttggtca acttggctat ctaagtcgtc aaaggcaatt ttagcatcag aataagagaa
     1801 gcccttgtta gtcaagttct ggataatctt atcttgcagg gcacgagctg gaagttttcc
     1861 ctcatatttt ttcaatagtt tattagctac acgttgagca acttcagaaa aatcaaattc
     1921 tttcaagttc tcttctatag tagattttga aatccctttt tgagctagtt tctgagtcag
     1981 cacataagga cccttgtctc ctgaaagttg attggtattg atgatagtat aagcgtactg
     2041 accatcatta atccacttat cttctttaag attagcaata acttgagaaa cgatgttttc
     2101 atcaatatcg tattttttca gatattctct gacttctttt tcagtgcgtg ctttaaagga
     2161 taagtggtag agggccagat tcttaccata agaaaactgg gcaaaatcct gaatctcggt
     2221 cagttcctct ttactaatga ccttatctct cgataacata aaacgaacaa ttgtgtcttc
     2281 ggtgatatag catttgtcga cattatcaag ctccatcaga tagagtcttt ttttcttttc
     2341 aagttttgtg attttcataa tttcctttca tctaaatgct tcgaaagctg caacaagtcg
     2401 gagtttatcc atatttacat attctctacc gtaatagtcg agaaataatt cagcatacgt
     2461 agcatcttgt aggttgtaat gaagggacca aattgcccaa aagaggtcga tatgtcggtc
     2521 actaaaacca gccaatccca agtcaataaa gcaagaaaaa tgagaggcat ccttcaagat
     2581 gaaatttggc aggcaggcat ctccatgaat aaaagcatca gctttgagaa tgtaaccttt
     2641 ctcttgtatc agttggtaag cttcttcacg actgtgaatg tgaaattgag gcagaagagt
     2701 cttgttataa aaagtcccct tctgatagtt ttttaaggct ttttctttat aacgcttcag
     2761 atgattttcc gacggaaaag attgtggttt aagactgtga agtttgttta atgcttgagc
     2821 cagggtttga cagagttttt cgggttgatt taaaaaagcg agagcgttgc tgccaatggc
     2881 ttctttagtc agaaggaagt ccttatttgc tgataaatag gtaatcactg gagttcccaa
     2941 tccttcagtt tcgaaccaac ttgtaatctt agcttcttga gctaatctgc ctttttgatc
     3001 tatttttaaa tagtaacctg aatctatata taggacagtt gcacttgaat gagaagaact
     3061 atcagagaga ttagctccct tgatatagct tcgtaattgt tcagggaaat ctagtatact
     3121 aaagcgaggt gtttttgaat tcatgctttt attgtaacat attcttaaat atcttagaaa
     3181 ctccatggta taatagacat atgaatctga aagtgaaaca aaaaatacca ttaaaaatca
     3241 agcgcatggg aattaacggt gagggaatcg gcttttacca aaaaacatta gtctttgtac
     3301 caggagctct caaaggcgaa gatatctatt gtcagattac ttctattaga cgcaactttg
     3361 ttgaagcaaa attactgaag gtcaacaaga agtctaaatt tcgaattgtg ccatcttgta
     3421 ctatttataa tgaatgcgga ggctgccaaa tcatgcacct gcattatgat aagcagctgg
     3481 agttcaagac ggacttactt catcaagcgc tgaaaaaatt tgctcctgca ggatatgaaa
     3541 attatgaaat tcgtccaact attggaatgc aggaaccaaa atattacaga gctaagttac
     3601 aatttcagac tcgaaaattt aaaaatcagg tcaaggcggg cttatatgca caaaactctc
     3661 actatttagt agagttgaaa gactgcctgg tacaagataa ggaaacccaa gtgattgcta
     3721 atcgcttagc agaattactt acttatcacc agattccaat cacggatgag agaaaagttc
     3781 taggtgtccg tactattatg gtccgacgcg cgagaaagac cggacaggtt cagattatta
     3841 ttgttacaaa ccgccagctt aatttaactc aattggtaaa agagttggtt aaagatttcc
     3901 cagaagttgt gacagtagct gttaatacaa atacagctaa aaccagtgag atatatggtg
     3961 aaaagacaga gattatctgg gggcaagaga gtattcaaga aggtgtactc aattatgaat
     4021 tttcactatc ccctcgagct ttttatcaac taaatcctga gcaaacagaa gtcctctata
     4081 gcgaagcagt aaaagcgctg gatgttgata aagaagacca tttgattgac gcttattgtg
     4141 gagttggaac gattggattt gcctttgcaa agaaagtaaa aacactcaga ggtatggata
     4201 ttattccaga agctattgaa gatgccaagc gaaatgctaa aagaatggga tttgacaata
     4261 ctcattatga agctggaacg gcagaagaga ttattcctcg ttggtacaag gaaggctacc
     4321 gagcagatgc tttgattgtt gacccaccac gtacaggtct ggatgataag ttattagata
     4381 ctattcttac ttatgtacca gaaaaaatgg tttatatttc ttgtaatgtt tcgaccttgg
     4441 ctcgtgattt ggtacgctta gtagaagtct atgatcttca ttatatccag tcggtcgata
     4501 tgttcccaca tacagctcga actgaagctg ttgtaaaatt aataaaaaaa gtttaaaaaa
     4561 gg
//
LOCUS       DAVDHC010000068         4556 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVDHC010000068 DAVDHC010000000
VERSION     DAVDHC010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4556
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.069"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            1..361
                     /locus_tag="VUR43_002215"
                     /pseudo
     CDS             1..361
                     /locus_tag="VUR43_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(354..521)
                     /locus_tag="VUR43_002216"
     CDS             complement(354..521)
                     /locus_tag="VUR43_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET5413827.1"
                     /translation="MKKRILSAGLTFTSALLLAACGQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(686..2293)
                     /locus_tag="VUR43_002217"
     CDS             complement(686..2293)
                     /locus_tag="VUR43_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET5413828.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNEDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENKKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGAKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTAAKEVLEKRVLAPWDAFCVELL"
     gene            2446..3930
                     /locus_tag="VUR43_002218"
     CDS             2446..3930
                     /locus_tag="VUR43_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET5413829.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVSEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4025..4507
                     /locus_tag="VUR43_002219"
     CDS             4025..4507
                     /locus_tag="VUR43_002219"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET5413830.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKGSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1327 a         1042 c          868 g         1319 t
ORIGIN      
        1 aagaagatat cagaggattt ctttggttgc aggtctaaca aatggtgagt taatcgctcc
       61 aatgacttac gaagagacga tgacgagcga cttttttgaa gcttggtttc agaagttttt
      121 cttaccaaca ttaaccacac catcggttat tattatggat aatgtaagat tccatagact
      181 ggggaagcta gaacttttat gcgaagagtt tgggcataaa cttttacctt cttcctccct
      241 actcacctga gtacaatcct attgagaaaa catgggctca catcaaaaag cctcgtaaaa
      301 ggtattacca agttgcaata ccttttatga ggctcttttg tcttgttctt gtttcaattg
      361 actatattat cagcgtaata gtctaataga tagttaaatg tagttggatt tccactaaag
      421 gttgatgagt aagtttttgt atctgaacct gattggccgc aagcagctaa aagcaaagca
      481 gatgtaaaag tcaggcctgc actaaggata cgcttcttta tgttcgtctc ctttctcctt
      541 aatagtggga atttgtaaag ttaattgaat ttcgagaatg aaggtttata aaccttggtt
      601 ataaaaaaca aaggatttct gccttttata cagtcctccc ttgtttttat acgatttcaa
      661 ttttaaattt ttctgcaaaa aatatttata gtaattccac acagaaagca tcccatggag
      721 ccaagacccg tttttcaagt acttctttag ccgcagtgtt ttcaatcaag acagatttga
      781 cttttccttc tactgtcaag tcttgctctt cattggacaa gttagccaca actaggaagc
      841 gacggtcgcc atccttacgt atataagcaa agaccttatc agccgtatca agcaattcaa
      901 agtcagctcg aattagccag ctattctcct tgcgaatttg gaccagtttc tgataggtat
      961 agaaaataga atctggattt gccagcgctt cttggacatt gatcatctcg taatttggat
     1021 taaccgccaa ccaaggttga cctgttgaga aaccagcgtt tttgctctcg tcccattgca
     1081 taggggtacg ggcattgtca cgtccaataa cacggatact gtccatgatt tcttcaatcg
     1141 gaacaccttt ttcaagagcc tcacgcgcat agttgagaga ttcaatatct tctacttgat
     1201 ccagtgtttc aaacggatag ttggtcatcc caatctcctc accttggtag atataaggag
     1261 ttcctctcat aagatgaagc aagattgcaa aggctttggc agatttttcg cggtattctt
     1321 ggtcatttcc ccagattgag acgatacgag ggaggtcatg attgttccag aagagggaat
     1381 tccaaccgtc ctcaactcct aactctgtct gccatttgtt gaagatttct tttaacttag
     1441 cgatattcag ctctttttga tagtgccatt taggctgacc ttcctgatac tgaagaccga
     1501 tatgttcaaa ctggaagacc atagacaatt cttgcccctt tggatcagag tagagcttgg
     1561 caatctctgg cgttgctccc caagtctccc ctactgtcaa gagatcctta gctccaaagg
     1621 tcgcctgatt catttccttg agatagggat ggagcatagg accattattg actaccttct
     1681 catcaggaat tttgccaatc atgtcaataa catccatacg gaaaccacca atacctttat
     1741 caatccagaa gttcatcatc tcataaattt tctggcgaag ttttttattt tcccagttga
     1801 gatccggctg tttcttgctg aaaaagtgga gatagtattg accagatttt tcatcgtatt
     1861 cccaagcaga tccactaaaa atagaatcta aatcgttagg ctcatcccgc cagatatagt
     1921 aatctcgctc agggctatta ggattttcac aggcctctac aaaccaggca tgctcatccg
     1981 aggtatgatt gaccaccaag tccatgatga tacggatatc acgcttctta gcttctgcaa
     2041 tcagttgatc catgtcctcc atggttccaa aaatagccgc aatcgcttga taatcagcaa
     2101 tatcatagcc attatcatcc atagggctgt cataaacggg agaaagccaa attgctgtga
     2161 ttcctagctt ggctagatag tccaacttac tggtaattcc tggcaaatcg ccaattccat
     2221 cttcattact atccataaaa ctctttggat agacttgata gactacggca ttgtgccacc
     2281 atttttcttg catcttctta cctcattatt ttcataatct atagtctatg atagcacttt
     2341 ttaaaatttt gtgcaagcgt ttgcttaatc tttttaattt cttttttagc tccgtagttt
     2401 cctaacttcc aattttttat tataatagag tccagaggta aaaaaatgaa aaaacaagct
     2461 tttagttctg aacaatattt aaatctacaa cgcgaccaca tcttagagcg cattaaccaa
     2521 tttgacggca agctttacct agagtttggt ggcaaaatgt tagaagattt ccacgctgct
     2581 cgtgtccttc ctggttatga acctgacaac aaaatcaagc tcttgcaaga attgaaagag
     2641 caagttgagg ttgtgattgc cattaatgct agcaacattg aacattccaa agcacgtggc
     2701 gacttgggca tttcttatga ccaagaagtt cttcgtttga ttgacaaatt caatgaatta
     2761 gggatttttg ttggttccgt tgtcattaca caatacgctg gccaacccgc tgcagatgcc
     2821 ttccgcaacc aacttgagaa aaacggaatt gattcttatc ttcattatcc aatcaaagga
     2881 tatccgacgg atatggatca catcatttcc ccagaaggca tgggcaaaaa cgactacatc
     2941 aaaaccagtc gcaacttgat tgtcgtaacc gctcctggac ccggttctgg aaaattggca
     3001 acgtgtatgt ccaatatgta ccacgaccaa atcaatggca tcaaatctgg ctacgctaaa
     3061 tttgaaacct tccctgtttg gaatcttccc cttcatcatc cagttaactt ggcttatgaa
     3121 gctgcaacag ctgaccttga tgatgtcaac atgattgacc ccttccatct tcaaacctat
     3181 ggagaaacca ctgtcaacta caaccgtgat atcgaaatct tcccagtgct caagcgcatg
     3241 ttggaacgta ttctcggaaa atcaccatac gcttcaccga cagatatggg tgtcaacatg
     3301 gttggtttcg ctattacaga tgacgaagct gctgtcgaag cttctaaaca agaaatcatc
     3361 cgccgttact atcaaacagt tcttgacttc aaagctgaaa aagttagcga agctgccgtc
     3421 aagaaaattg agttgctcat gaacgacctc ggtatcacac ctgcagaccg taaggttgct
     3481 gtcgttgcgc gccaaaaagc agaagaaact ggtggaccag ccctagcctt tgaattgcca
     3541 aatggggaaa tcgtcactgg taagaactca gaactctttg ggcctacagc cgctgccttg
     3601 atcaacgcca tcaaaaaatc agctgacatc gctaaagaag taaaactaat cgagcctgaa
     3661 gttgttaagc caatccaagg tcttaaaatc gatcatctcg gtagccgcaa tccacgcctt
     3721 cattcaaatg aaatcctgat tgcacttgct atcacagcta cagaaaatcc tgatgctgcc
     3781 cgcgctatgg aagaactcgg caacctcaaa ggaagcgaag cccactcaac catcatcttg
     3841 actgatgaag acaagaatgt ccttcgtaaa ctgggtatca acgtaacctt tgacccatac
     3901 taccaatacg accgcttata tcgtaagtaa agatttcaac ctccccagcc tcggagaggt
     3961 tttctctctg tctcaggagc aacctttatg atataatgag aggagaaaac tgaaaggatt
     4021 taccatgtca aaagaagtta ttgtcgaaag ttttgaactt gaccacacca ttgtcaaagc
     4081 accctatgtt cgcttgattg gggaagaaac aggaccaaaa ggagacatca tctccaatta
     4141 tgatattcgc ttggtgcaac caaacgaaga ctctatccct actgccggcc ttcacactat
     4201 cgagcacctc ttagccaaac tcatccgtac ccgcattgac ggcatgattg actgttcacc
     4261 atttggttgc cgcacaggct tccacatgat tatgtgggga cgtcacacca gtgctaaaat
     4321 cgcagctgtt atcaagggtt cgctcaagga aatcgctgaa actactactt gggaagatgt
     4381 cccagggaca accatcgaat cttgcggaaa ctacaaggac cacagcctct tctctgctaa
     4441 agaatgggca aaactcatct tggaacaagg gatttcagat gatgcctttg aacgtcatgt
     4501 gatttaaaat cgagtagggg ataatctcca gcccctctca caccaccgta cgtacc
//
LOCUS       DAVDHC010000069         4482 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVDHC010000069 DAVDHC010000000
VERSION     DAVDHC010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.070"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(8..748)
                     /locus_tag="VUR43_002220"
     CDS             complement(8..748)
                     /locus_tag="VUR43_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET5413831.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(748..2313)
                     /locus_tag="VUR43_002221"
     CDS             complement(748..2313)
                     /locus_tag="VUR43_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET5413832.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAIKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLIKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            2452..4341
                     /locus_tag="VUR43_002222"
     CDS             2452..4341
                     /locus_tag="VUR43_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET5413833.1"
                     /translation="MKKTFFLLMFGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
BASE COUNT         1235 a          818 c         1032 g         1397 t
ORIGIN      
        1 tttcttttta tttgagatag cgttgaagga actcttttgt tcggtcttct ttaggattgg
       61 tgaagaggtc ttctggttta ccttcttcag cgatcacgcc cttatccata aagataacac
      121 ggtgagagac atcacgggca aattccattt catgggttac gacaatcatg gtcaagcctt
      181 cctgagccag gtcctgcatg attttgagga cttctccaac catttctgga tcgagagctg
      241 atgttggttc atcaaagaga atagcgtccg gattcatgga gagggcacga gcgatggcca
      301 cacgttgttt ttgaccacct gagagttgtt ttggtttggc ttgccagtag cgttctccca
      361 tgccgacctt ttccaggttt tctttggcaa tcttttcagc ttctgtgcgt tcgcgtttta
      421 ggacagttgt ctgagcgacg attgtgtttt caagaacatt gagattttca aagaggttaa
      481 aggattggaa aaccatcccc aacttttcac ggtattgcgt gaggtcatag cctttttcga
      541 ggacgttttg tccatgataa aggatttgtc catcagttgg tgtttcaagt aggttaatgg
      601 agcgtaggaa ggtcgatttt ccgcttccag agcttccgat gatagagatg acctctccct
      661 tgtggacagt gagtgaaatg tcttttagca cttcgttttg tccataggat tttttgaggt
      721 gtttaatttc aaggattgct tgtgtcatta tttcaaatcc tccgtttgca tttggttagc
      781 acctgtagtg taggtatcca tgtccattct gcgctcgata aagcgtagga tacgtgttac
      841 ggtgaaggtg aggacaaagt aaatcacggc gatgattgta aatgtctgga agtattgata
      901 ggtttgtgtt gccacggtat ttcctgagaa ataaagttcg acaacagaga taacgttcaa
      961 tacagatgta tctttgatat tgatgacaaa ttcattacca gttgcaggta ggatgttacg
     1021 gactacctga ggtaggacaa tcttacgcat ggtctggtta tgggtcatac caagagcagt
     1081 cgcagcttca aattgtccct tgtcaactgc taggatacca ccacggacga tttcagtcat
     1141 gtaggcaccg gtattgattg aaacgatgaa gatagcagcc agtgtacggt caaggttgat
     1201 cccgaaagct tgggcagttc catagtagat aaccatcgat tgaacaatca ttggcgtacc
     1261 acggaaaatt tcaatgtaga cattgagaac ccagccgact agtttttgaa ggccataaat
     1321 ggctttgttt tcagagagag gagcagtacg gaagacacca atggcaagtc caataatgag
     1381 acctatgatg gttccgacga tagagattaa aagagtgata ccagcaccac gcaagagttg
     1441 ttgccagttt tcagaaagaa ttttagcgac ttggctaaag aaactactgc tagtctcttc
     1501 agttgttgta gcttcggcag gttgttcctt gatcatacga tccatcaagg caacttggtc
     1561 atcttttgaa atggtttcaa tgctggcatt gatttggcta atacgattgt catttttacg
     1621 aagcccgata gcgatagctg tatcttcttc cccagttttg aaaccaggtt ctacttgaat
     1681 catcttgaac ttagagttcg cagcttcagc agtcagtgct tctggacgtt cagaaacata
     1741 agcatcaatg acaccagcct caagagcttg gcgcatttga gcgaagtctc ccatggctgt
     1801 ttctttttta gcacctggga tttgtgcaat caagtcgtag aggtagaccc cttgttgaga
     1861 agtgattttt gcaccgttaa agtcatccaa agatttagca cttgcgtagg cagaatcttt
     1921 tttgataagc aaaactggtt cgctagtata gtaactgctt gaaaaggcaa tttcttgttt
     1981 gcgttcggca gtaggactca tacctgcgat aatcatgtca atcttaccag aagtaagggc
     2041 agggactaga ccttcccact tggttttaac aaccaaaggt tctttaccta agtccttagc
     2101 gattttcttg gcaatttgga catcgtatcc attggcgtac tggttggttc catcgatttt
     2161 gatagctcca ttgctatcat catcttgggt ccagttaaag ggagcatatg ctgcttccat
     2221 cccgatgcgt aaatattcat cggcttgagc aacattgaca agtcctagca tcagcaagag
     2281 acttgtgaaa atagataagt atatttttct catgatttct cctatttcta atctattaaa
     2341 aaataactgt ctcctatttt atcgaaaaat gcgtaatttt tcaacataag taagccttta
     2401 cttacgaaaa aatgctataa tgataagaaa gataaaaagg gggcttaatt gatgaaaaaa
     2461 acttttttct tactgatgtt tggcttgttt tgccttctgc cactttctgt tttcgccatt
     2521 gattttaaga taaactctta tcaaggtgat ttgtatattc atgcagacaa tacggcagaa
     2581 tttagacaaa agatagttta tcagtttgag gaggacttta agggacaaat cgtgggactt
     2641 ggacgtgctg gtaagatgcc tagcgggttt gacattgacc ctcatccaaa ggttcaggcc
     2701 gcgaaaaacg gtgcagaact agcagatgtg actagcgaag taacagaaga agcggatggt
     2761 tatactgtga gagtctataa tccaggtcag gagggcgaca tagttgaagt tgacctcgtc
     2821 tggaacttaa aaaatttact tttcctttat gatgatatcg ctgaattaaa ttggcaacct
     2881 ctgacagata gttcagagtc tattgaaaag tttgaatttc atgtaagggg agacaagggg
     2941 gctgaaaaac tctttttcca tacagggaaa ctttttagag agggaacgat tgaaaagagt
     3001 aaccttgact atactatccg tttagacaat cttccggcta agcgtggagt tgagttgcat
     3061 gcctattggc ctcggaccga ttttgctagc gctagggatc agggattgaa agggaatcgt
     3121 ttagaagagt ttaataagat agaagactcg attgttagag aaaaagatca gagtaaacaa
     3181 ctcgttactt gggtcctccc ttcgatactt tctatctcct tgttattgag tgtctgcttc
     3241 tattttattt atagaagaaa gaccactcct tcagtcaaat atgctaaaaa tcatcgtctc
     3301 tatgaacccc caatggaatt agagcctatg gttttatcag aagcagtcta ctcgacctcc
     3361 ttggaggaag tgagtccctt ggtcaaggga gctggaaaat tcacctttga tcaacttatt
     3421 caagctacct tgctagatgt gatagaccgt gggaatgtct ctatcatttc agaaggagat
     3481 gcagttggtt tgaggctagt aaaagaagat ggtttgtcaa gctttgagaa agactgccta
     3541 aatctagctt tttcaggtaa aaaagaagaa actctttcca atttgtttgc ggattacaag
     3601 gtatctgata gtctttatcg tagagccaaa gtttctgatg aaaaacggat tcaagcaaga
     3661 gggcttcaac tcaaatcttc ttttgaagag gtattgaacc agatgcaaga aggagtgaga
     3721 aaacgagttt ccttctgggg gctcccagat tactatcgtc ctttaactgg tttggaaaag
     3781 gctttgcaag tgggtatggg tgtcttgact atcttgcccc tatttatcgg atttggtttg
     3841 ttcttgtaca gtttagacgt tcatggctat ctttacctcc ctttgccaat acttggtttt
     3901 ctagggttag ttttgtctgt tttctattat tggaagcttc gactagataa tcgtgatggt
     3961 gttctaaatg aagcgggagc tgaggtctac tatctctgga ccagttttga aaatatgtta
     4021 cgtgagattg cacgactgga taaggctgaa ttggaaagta ttgttgtttg gaatcgtctc
     4081 ttggtctatg caaccttatt tggctatgcg gacaaggtta gtcatttgat gaaggttcat
     4141 cagattcaag ttgaaaatcc agatatcaat ctctatgtag cttatggctg gcacagtatg
     4201 ttttatcatt caagcgcgca aatgagccat tatgctagtg tcgcaaatac agcaagtacc
     4261 tactccgtat cttctggaag tggaagttct ggcggtggct tctctggagg cggaggtggc
     4321 ggcagtatcg gagcctttta aagagagcta ccatagactg aaaaagtatg atataatgga
     4381 agatagaaga aagacaaact ataagaaaag tcaatagttt tatctaaact atttcttatt
     4441 tcaatttgat gatttggcga tgattttaga gcacggcaaa aa
//
LOCUS       DAVDHC010000070         4450 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVDHC010000070 DAVDHC010000000
VERSION     DAVDHC010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4450
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.071"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(60..1163)
                     /locus_tag="VUR43_002223"
     CDS             complement(60..1163)
                     /locus_tag="VUR43_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET5413834.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEVSHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            complement(1180..1977)
                     /locus_tag="VUR43_002224"
     CDS             complement(1180..1977)
                     /locus_tag="VUR43_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET5413835.1"
                     /translation="MLASEVIKRYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVTEAIEKGVDLIIVKHAPIFRPIKDLVASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNVQSQTFWELTQQVKQVFGLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVIFVEKIAALLSQWKEDKGWSIDILPSQASTNPFHHI"
     gene            complement(1964..2641)
                     /locus_tag="VUR43_002225"
     CDS             complement(1964..2641)
                     /locus_tag="VUR43_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET5413836.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEEADQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEFLVVEVGEM
                     ELSARDTRFGPFLSREISPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHASK"
     gene            3191..3659
                     /locus_tag="VUR43_002226"
                     /pseudo
     CDS             3191..3659
                     /locus_tag="VUR43_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3653..4245
                     /locus_tag="VUR43_002227"
                     /pseudo
     CDS             3653..4245
                     /locus_tag="VUR43_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
     gene            complement(4255..>4450)
                     /locus_tag="VUR43_002228"
     CDS             complement(4255..>4450)
                     /locus_tag="VUR43_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HET5413837.1"
                     /translation="DNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNK
                     RIKVKLKGLSLVQYRTKSFG"
BASE COUNT         1388 a          926 c          814 g         1322 t
ORIGIN      
        1 cagtgctttg agtaacccgc ggctagtttc ctagtttgtt ctttgatttt tattgagtat
       61 tattcgcttt ttactcgttt gacatagttt tcaattgggt aatttagagg gtccaaggtc
      121 aactccttgt cttggatcag ttgggctaga tggtaaccaa tgataggacc agttgtgagg
      181 cctgatgaac ctagtccact ggctgcatag acaccagtta agtcaggcac ctgcccaaag
      241 aaaggagaga aatcactggt gtaggcacgg attccaacac gctcagattt tgaagtagct
      301 tcagccaaaa tcagatagtg agtcaaggtg gcctcctcca tttgttggag caaggtttca
      361 tctaccgtca aatcaaatcc catgtcattt tcgtgggtag cgcctaagga taatttccca
      421 cctgcaaagg gaatcaaatc ccactcccct tctggcatga caacagggta atcttccatg
      481 tcttgggcaa gctgataatc tcgtagttgt cctttttgag gacggacatc cacttcataa
      541 cctaaaggct ctaacatgtc ccccaaccaa gctcccgtcg ccaaaataac ctgctcaaac
      601 tcctcttcac caatctggta gcctgatgct aacggtgtca gagtcacttt ttctttgacc
      661 agcttgacat gactgacttc cagcaaacga gtcactaaaa gttggccatc tactctcgct
      721 ccaccagaag catagagcag gcggtcaaat ccctgcaaac cagggaataa ttcattagct
      781 gaggcttggt tcagaatggc taattgccct atcaagggag attcttctct gcgctggagg
      841 gccagttgat aaagttcttc caacttggat tcatcctttt tcaagagaaa gactcccgaa
      901 cgctggtaaa agtcgatttc ttgtcctgat ttctctaaat cagctaataa atccacataa
      961 aaatcagccc ccaagcgcgc catcttgtac caggctttat tacggcgttt ggaaaaccaa
     1021 ggactgataa ttcctgctgc ggccttggtg gcttgacctt gctcatggtc aaaaacggtc
     1081 acctctaggt cactttctct cgagaggtag taggcagctg ttgctcccac aattcctgct
     1141 ccaataatgg caactttttt cattgtcttc actttctaac tagatatgat ggaaaggatt
     1201 ggttgatgcc tgactaggta agatatcaat agaccacccc ttatcttcct tccattgact
     1261 aagaagtgct gcgatttttt ctacaaaaat cacttcgata tagtgacctg ggtccaatgc
     1321 aagcaaccca tcagatagca tatcctgagc agtatggtag tagatatctc cagtaatgta
     1381 gacgtctgcc cccttagcta aagcatcctt atagaaagac tgcccactac caccgcagat
     1441 agccactctt gaaataggct tctgtaagtc attctcttga taatgcacca ttcgaaggct
     1501 atctaggcca aagacttgct tgacctgttg ggtcaattcc caaaatgtct gagactgaac
     1561 attcccaata cgtccaattc cacgttcagg acctgtctcc tgtagataag tcgtctcctc
     1621 aatgcctagc atctgacaaa accagtcatt gagaccattt tcaacgatgt caatgttggt
     1681 atggctgaca tacactgcaa tgtcatgctt gattaggtcg atataaatct gattttgcgg
     1741 acggctggca accaagtcct tgatgggacg aaagataggc gcgtgcttga cgataatcaa
     1801 gtctacaccc ttttcaatgg cttcagtcac cgtttcttca cgaatatcga gagccaccat
     1861 gaccctttgg atacccttgt ctaaagtgcc aatttgcagg ccacggctgt ctccttccat
     1921 agaaaattcc tgagggcaaa aggcttcata gcgtttaatc acttcacttg ctagcatgga
     1981 gaacctcctt gatggcttga atcttatcta ctagaacttg acgttcttcc agattttttt
     2041 ctgggatttg tccgagggca aactctagct tctcagcttc tttttgccat ttttggacaa
     2101 atactgggct gatttccctt gacaagaagg ggccaaaccg ggtatctctt gctgataatt
     2161 ccatttctcc aacttccact actagaaact cataaaactt tccagcttct tctaagatgc
     2221 tttctgctac aatctggaat ccatgatcct gtagccagat acgcaagtcg tcttcacgat
     2281 tattgggctg gaggatcaaa cgctctacat tagctaactt ccccaaacct tcttctaaaa
     2341 tcctagcaat caaacgacca cccatgccag caatggtaat gacagacact tggtctgctt
     2401 cttcaaaagc tgccaagcca ttggctaaac ggacttggat tttctccttt aggccgtgcg
     2461 cctcaacatt tttgaccgca gattggtagg gaccttccac cacctcacct gcaatggcac
     2521 ttttgatttg tcctctttcg accaactcga taggcagata agcatggtca ctccccacat
     2581 ctagtaaaat agcgccctgt ggcacaaagg aagccaccaa ttctaatctc tttgaaatca
     2641 tcttctctca ctttccaaaa ctctattacc tcttattata ccacatttca atcttcaact
     2701 tcccagtaat ataagcacct ctggcgaaag aagtttcaat gtcctaaagt aataagtgaa
     2761 tccaattgaa agattttaaa caatttgcaa aaatgtcaaa aaataaaaaa taaacagttt
     2821 attcagaaaa ttcttgacat ataaaaaaca catggtagaa tataattaga aagttagaaa
     2881 aaataaaagt ttgactaaaa tttgtatttg aaggtggtgt tcagataaga aatttagtca
     2941 gacgaaccac gaatttgctc tatgctttct ggaatttatc ataacaggag gatacagtca
     3001 tggaacaaac attgtttgaa ttagaactac ttccagagga agatgtcatt gtcacaggtc
     3061 tccctaagta ttgttctttt acttgtttaa ttacaggtcg ctagttatat tttatataaa
     3121 ataagtagct ttacttacgg aataggctag tgctgtgtct ctagcctatt ttaataatta
     3181 ggagtttgtt atggatttat tagagaaaga atgtttaaaa tgtgataaaa atttccaaca
     3241 gggcgatatt tggaattact attatttatc agataaggtg cctgcacaag ggtggaaaat
     3301 acacataagc tcccaaataa aagacgctgt aaatattttt aagattgtgt ataaactatc
     3361 ccaactaaat aattgtagct ttaaagttgt taaaaattta gaggaattaa aaaaaattaa
     3421 ttcccctagg gaaatgagcc ctactgctaa caaatttata actctatatc ctaagtcaga
     3481 atctgaagct aagagtatga tttgtaatct tacgaataaa ctgtcagaat ttaaggctcc
     3541 aaaaatacta tctgactatc aatgtggaat gcattctcca gttcattata gatatggggc
     3601 ttttttaaaa aaacaagctt atgatgaaaa aaataaaaaa gtcatctatt tattgctaga
     3661 tgaaaaaagg aagaactatg tagaagataa gagacaaaat ttccctagtc ttcctagctg
     3721 gaaaatggat ttattttcag aagaagaaaa aggatttatt ttcaaaccac atgtgaagtt
     3781 tcaagtaagg actctgcaat aaataaatac aaaatagaaa aaattattaa gagatcaaat
     3841 aaaggaaatg tttatcgggc aattagaaaa tcggacgggc aaaaagtaat catcaagcag
     3901 tcaagacctt ttgtgaatta tgatgccgaa ggagaatgga cagcacttga tgatataaaa
     3961 aatgaggctt acatgctaaa aaagttagcc gataaaagtt atactactaa tttaattgat
     4021 gaattttata tcgtggatga ttattttctt gttcaggaac aagttgacgg gttaaacttt
     4081 gaagaattta ttcgagaaac agaatactcc ttaaatatta gagaaaaatc actggacaac
     4141 attgtgaata tagtaaatga catccataaa ctgggatata aaattgtaga tatagctcct
     4201 acaaatttta tatataccaa aaatgtactg caccccaaaa gttagacaat taatttatcc
     4261 gaaggattta gttctgtact gcacaaggct aagtcctttt agttttacct taattcgttt
     4321 gttgttgtag taatcaatgt agtccacaat agcttgttca aggttttcta aagatctaaa
     4381 gttcttctca taaccataaa acatctccga tttcaaaatg ccaaagaaag attccatcat
     4441 gccgttgtct
//
LOCUS       DAVDHC010000071         4358 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVDHC010000071 DAVDHC010000000
VERSION     DAVDHC010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4358
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.072"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..163)
                     /locus_tag="VUR43_002229"
     CDS             complement(<1..163)
                     /locus_tag="VUR43_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HET5413838.1"
                     /translation="MNELINVTLNENQEPVVSARQLHQTLEVKKRFSAWFKANSKLFI
                     ENEDFTSVQT"
     gene            complement(176..412)
                     /locus_tag="VUR43_002230"
     CDS             complement(176..412)
                     /locus_tag="VUR43_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HET5413839.1"
                     /translation="MSNDYSKLAGKIVEKYGTQYNFAQAMGLSERSISLKMNNRVPWK
                     DFEMAKASELLDIDVNQLHEYFFTPKVHVREQIA"
     gene            582..1385
                     /locus_tag="VUR43_002231"
     CDS             582..1385
                     /locus_tag="VUR43_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET5413840.1"
                     /translation="MRSSNPSERLKQLMSERNLKQVEILEKSLPYQKELGIKMGKSTL
                     SQYVNGVQSPDQHRIYLLSKTLEVSEPWLMGYDVEKKRIPDSERNSISNEQPEILPIY
                     NKLEEPRQEKVLDFAKKQLEEQKKSKASSIFDKSQDGDDYITDYVEGLVAAGHGTFQE
                     DNLHMEVRLRAEDVPEDYNTIAKVAGDSMEPMIEDNDLLFIKVTNQVDINDIGIFQIN
                     GKNFVKKLKRDYNGGWYLQSLNNSYEEIHLTENDDIRTIGEVVSVYREK"
     gene            1387..2151
                     /locus_tag="VUR43_002232"
     CDS             1387..2151
                     /locus_tag="VUR43_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HET5413841.1"
                     /translation="MSKENPYFEQTKQNYIEVEKLYKLGKAKHTSSKYRFLAPAVKRQ
                     SEQFLFEAKTQKRKYWKFNRGSLIFVEFGVNIGGELSNNHWAIVLDKVDSPYKKTLTV
                     IPLTSKNQIDTVLIDEIIAEYPSILLDEYIEKLHKELFAYLKYLDSNNAITEAALSDV
                     YQAYTEQFSNEIIQPKIVDDDNLKRTQSEITDIIELTQYYKKYIKRSYAKCNNLQTIS
                     KDRILKKNRLDPIGKMKVSDNTLDKINEKLKELYLF"
     gene            2430..3875
                     /locus_tag="VUR43_002233"
     CDS             2430..3875
                     /locus_tag="VUR43_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET5413842.1"
                     /translation="MKTMNKVAIYVRVSTTNQVEEGYSIDEQKDKLSSYCDIKDWNVY
                     KVYTDGGFSGSNTDRPALESLIKDAKKRKFDTVLVYKLDRLSRSQKDTLHLIEDVFIK
                     NGIEFLSLQENFDTSTPFGKAMIGLLSVFAQLEREQIKERMQLGKIGRAKAGKSMMWA
                     KTSYGYDYHRETGTITINPAQALAIKFIFESYLRGRSITKLRDDLNEKYPKHVPWSYR
                     AVRTILDNPVYCGFNQYKGEIYPGNHEPIISKEEYDKTQSELKIRQRTAAENVNPRPF
                     QAKYILSGIAQCGYCGAPLKIMLGVKRKDGSRLKKYECHQRHPRTLRGVTTYNDNKKC
                     DSGFYYKDKLEAYVLKEISKLQDDADYLDKIFSGDNAETIDRESYKKQIEELSKKLSR
                     LNDLYIDDRITLEELQSKSAEFISMRGTLETELENDPALRKNKRKADMRKLLNAEKVF
                     SMDYENQKVLVRRLINKVKVTAEDIVINWKI"
     gene            complement(3897..4154)
                     /locus_tag="VUR43_002234"
     CDS             complement(3897..4154)
                     /locus_tag="VUR43_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413843.1"
                     /translation="MKILNIELANVEQTDLGFEHWVDVTYQVPILKNEYTVKLLLLME
                     CRIEDQEVIEYLVSTWKYRDLVLHSVRMYEIEKSENFTILD"
BASE COUNT         1562 a          803 c          785 g         1208 t
ORIGIN      
        1 ccgtttggac acttgtaaaa tcttcattct ctataaataa tttagagttt gctttaaacc
       61 aagcgctaaa ccttttcttg acctctagtg tctgatgtaa ctgcctagct gatactactg
      121 gctcctgatt ctcattcagg gttacgttga tgagttcatt catgtgagct cctttctatg
      181 ctatttgttc acgaacatga actttaggtg taaaaaaata ttcatgtaat tgatttacat
      241 caatatctaa caactctgag gcttttgcca tctcaaaatc tttccaagga actctattat
      301 tcatctttaa agagattgag cgctctgaga gccccattgc ttgagcaaag ttgtattgag
      361 tgccatactt ttcaacaatc tttcctgcaa gttttgaata atcgttactc attagcttac
      421 tcctttcttg ttcatttttc atgaactgtt ttacaaaaca tattttatca cgttgaatga
      481 acctagtcaa gtaaaaaatt cattttttat gaactttctc ttgaattttt gttcaagatg
      541 gtttataata ggcttataaa caggaaaaag gaggaggttt catgaggagc agcaacccat
      601 ctgagcgact aaaacagctc atgtctgaaa gaaatttaaa acaagttgaa atacttgaaa
      661 aatcattacc ttatcaaaaa gaattaggaa taaaaatggg gaaaagtacc ctttctcagt
      721 atgttaatgg tgtacagtct cctgatcaac acagaattta cctgctttct aaaacacttg
      781 aagtaagcga accttggctt atgggctatg atgttgagaa aaaacgtata ccagatagtg
      841 agcgtaactc aatatcaaat gaacagcctg aaatcttgcc gatctacaac aaactagaag
      901 aaccaaggca ggagaaagtc cttgactttg ctaaaaaaca actggaagaa caaaaaaaat
      961 ccaaagctag ctctatcttt gacaagtctc aagatggcga tgactacatt actgattacg
     1021 tagaaggctt ggttgcagca ggacatggaa cgtttcagga agacaacctc cacatggaag
     1081 taagactgcg tgccgaagat gtccctgaag attacaacac tatcgctaag gtggctggtg
     1141 actccatgga accaatgatt gaagataacg acctgctctt tatcaaagtc acgaatcagg
     1201 tagatatcaa cgacatcggc attttccaaa tcaatggtaa aaactttgtt aaaaagctga
     1261 aacgtgatta taacggcggt tggtacttgc aaagcctcaa caatagctat gaagaaatcc
     1321 acctgacaga gaatgacgac atccgaacta ttggggaagt tgtcagtgtg tatagagaga
     1381 aataaaatga gtaaagaaaa tccatatttt gaacaaacca aacaaaacta catagaagtt
     1441 gaaaaactct ataaacttgg taaagcaaaa catacatctt ctaaataccg atttcttgca
     1501 ccagcagtta aaagacaatc tgaacaattc ttgtttgaag ctaagactca aaaaagaaaa
     1561 tattggaaat tcaatcgtgg ctctctgata ttcgtagagt tcggtgtaaa tataggcgga
     1621 gaattatcaa ataaccattg ggctattgtc ttagacaagg tagatagtcc ctataaaaaa
     1681 acactcacag taattcctct aacatctaaa aatcaaatag ataccgtact catagacgaa
     1741 atcattgcgg aatatccttc tattttgctt gatgaatata ttgaaaaatt acacaaagaa
     1801 ttatttgcct acctaaaata tttagattcc aataatgcaa ttactgaagc tgccttatcg
     1861 gatgtctacc aagcttatac agagcaattt tcaaacgaaa taattcaacc taagatagta
     1921 gacgatgaca accttaaacg gacacaatca gaaataactg acattattga attaactcaa
     1981 tactacaaaa aatacattaa gcgttcttat gccaagtgta ataaccttca aacaatcagc
     2041 aaagatagaa ttttaaagaa aaatagatta gatccaatcg gaaaaatgaa agtatctgat
     2101 aacacattgg acaaaattaa cgaaaagtta aaagaattat accttttcta atctcttgac
     2161 atttcttaat aattatatta caatacagct attaggagtt tagctccata aagtttacat
     2221 ttggatttta gatccataac gtgatggtag ccgtatttga tacggctact tttcttttta
     2281 tctagcaact gtttccattt tggaaacaac tcaaaaaagc cccacgctca gaagtttggc
     2341 gaccgagagc gtgaggctag gagcaagaaa aaagcattaa aaagctgttt ttcttgtacc
     2401 tattttatca aaaaaggggt acaaattcaa tgaaaacaat gaataaagtg gctatatatg
     2461 tcagggtttc gacgacaaac caggttgagg agggatactc tatagatgag caaaaagaca
     2521 agctctctag ctactgcgac attaaagact ggaatgtata caaagtatat actgatggag
     2581 gtttctcagg atccaatact gacagaccag cgctagaaag tcttatcaaa gacgctaaaa
     2641 aaagaaaatt tgacacagtt ctagtctata agctggaccg tcttagccgt agtcaaaaag
     2701 acacgcttca cttgattgag gatgtattca tcaagaatgg gattgaattt ctgagcttgc
     2761 aggagaactt tgacacctct actccttttg gtaaggctat gattggactc ttgagcgtct
     2821 ttgctcagct agaaagggag caaatcaagg aacgcatgca acttgggaaa ataggacgtg
     2881 ccaaggctgg aaaatccatg atgtgggcta aaacatccta tggatacgac taccacagag
     2941 agacaggaac tatcactatc aatccagctc aggctctggc cattaagttt atctttgaga
     3001 gttacctgag agggagatct attactaagt tgagagatga tctaaatgag aaatacccaa
     3061 agcatgtgcc ttggagctat cgggcggtca gaaccatact cgataaccct gtctattgtg
     3121 gtttcaatca gtataaggga gaaatttatc caggtaatca tgagccgatt atttcaaaag
     3181 aggaatacga taagactcaa tctgagctaa aaataagaca aagaacagca gcagagaatg
     3241 tcaatcctag accattccaa gctaagtaca ttttatccgg tatcgcccaa tgtggatatt
     3301 gtggcgctcc tttaaaaatt atgttaggcg taaagaggaa agatgggagc aggttaaaaa
     3361 aatatgaatg ccaccaaagg cacccacgaa cgctgagagg cgttactacc tacaacgaca
     3421 ataaaaagtg tgactcagga ttttactaca aagacaagct agaggcctat gtgctaaaag
     3481 aaataagcaa actacaagat gacgctgatt acctggacaa aatattttca ggagacaatg
     3541 ctgagaccat agaccgtgag agctataaga aacaaataga ggagctatca aagaaactga
     3601 gcagacttaa cgatctatac atagatgacc gcattaccct tgaagaatta cagagcaagt
     3661 cagccgaatt tataagcatg agggggactc ttgaaactga actagaaaac gatccagcac
     3721 tcaggaagaa caaaagaaag gctgatatga ggaaactgct aaacgctgag aaagtctttt
     3781 caatggacta cgaaaatcaa aaggtgcttg ttagaaggct tataaacaag gttaaggtga
     3841 cagctgagga cattgttatc aattggaaaa tataaataat tttagtaacc tacatttcaa
     3901 tcaaggatag taaaattctc actcttttct atctcataca tccttaccga atgcaacacg
     3961 agatcacgat acttccaagt gctgaccaga tactcaataa cctcttggtc ctctatcctg
     4021 cattccataa gtaataatag cttgaccgtg tattcattct tcaaaatcgg aacctgataa
     4081 gtcacatcta cccaatgctc aaaacctaag tctgtctgct ctacatttgc tagttcaata
     4141 tttaaaatct tcatttttat tcctcctact tatctattcg taaaagaaga taaaaagtta
     4201 tgaaaaaatc actatttttt tatttttaac aaaacaccgt ttttgacaat aatcaaaaaa
     4261 taaaaaggag ctattattaa caaaatggcg tttttggcaa taataccctg ccattcctcc
     4321 tccctattct tcatgtaaac gcttttttga agaatcag
//
LOCUS       DAVDHC010000072         4245 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVDHC010000072 DAVDHC010000000
VERSION     DAVDHC010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4245
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.073"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..1288)
                     /locus_tag="VUR43_002235"
     CDS             complement(<1..1288)
                     /locus_tag="VUR43_002235"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET5413844.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1366..2613)
                     /locus_tag="VUR43_002236"
     CDS             complement(1366..2613)
                     /locus_tag="VUR43_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET5413845.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VUR43_002237"
                     /pseudo
     CDS             complement(2804..3654)
                     /gene="rgg"
                     /locus_tag="VUR43_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            3778..4119
                     /locus_tag="VUR43_002238"
     CDS             3778..4119
                     /locus_tag="VUR43_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET5413846.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         1352 a          891 c          828 g         1174 t
ORIGIN      
        1 attgagtata aaatcctagt ttttcaaaga tttctgagaa gttttggctg attgtctcaa
       61 gtgacacttg cacttcttct cgggtttggt tgttcttgac cgtcacttgt ccgctttcga
      121 cttcgctctc tcctagggtg atgagggtct tagccgcaaa gacatcggct gacttgaact
      181 gagcttttag tttacggttg aggtaatcac gctctgcttt gaaaccttgt tggcgaagag
      241 cctgtaccaa ttccaaggcc ttgatatttg ccccttcgcc caagactgcg atatagacat
      301 ctagggcgtt ttcgataggg agggtcacac cttgcttttc aaggatgaga agcaggcgct
      361 ctacaccaag tccaaaacca aatccagcag tttcagggcc tccaaagtaa gcaaccaaac
      421 catcgtagcg accacccgca cagacggtca ggtcattgcc ctcaatctct gtgataaact
      481 cgaaaatggt gtggttgtag tagtccagac cacgcaccat attggtatcg atgatgtaat
      541 ctactccaag attttccaac atctgacgca cagcatcaaa atgagcttgg ctttcttcat
      601 caagaaagtc caagatagac ggcgcattct ctactgccac cttgtcttct ttttccttag
      661 agtccaagac acgaagagga ttttcctcca agcgacgttg gctatcctta gacaaggtct
      721 ccttgagcgg tgtcaaatag tcaatcaagg cttggcggta ggctgcacgg ctctcaggat
      781 ttccaagagt gttgaggtgc aatttgacac cttgaatacc gatttccttc aaaaaatggg
      841 ctgccatagc gattgtttcc acatcggtag ctggattgct agagccaaaa cactcaacac
      901 caatctggtg gaattggcgc aagcgccctg cctgtggacg ctcataacgg aacataggtc
      961 ccatgtagta gaacttgctt ggcttttgca cttctggggc gaaaagttta ttttccacat
     1021 aggaacggac aacgggtgca gttccttctg gacggagggt aatatgacgg tcacccttgt
     1081 cataaaaatc gtacatttcc ttggttacga tatccgttgt atctccgaca gagcgactga
     1141 taacctcgta atgctcaaaa ataggcgtgc gcacttctgc atagttgtag cgtttgaaaa
     1201 tctcacgggc aaagccctca acgtactgcc acttagcaga ctcagcaggt aaaatatcct
     1261 gcgttccttt tggtttttgt aatttcatag ggaatcctct ttaaacttaa tagtcttatt
     1321 ttaccataaa tagagggatt aaaacagtaa gaaaaaaatt aggatttaga tatcattttt
     1381 gagattaaga attgtcaaaa aaatagctag caaggaaaga ccaacaaata gcatccaagt
     1441 caactgtata ttccatacgg ctactagtga aaaacaagct gttcccacag gtatggataa
     1501 ggtaaacaat agacctaaaa aattactagt acgagctaga acctctggag ctagattttt
     1561 catgagcatg gcactaatct ttggttgaac tttaccagac acatacagag taaagaagag
     1621 aaatagcaaa ccaagcacga cttgattgaa taaattagcc aaaccaacta gactaagtcc
     1681 tacggtctcc cacatcatca atctaggcaa ggactgcttc ccaaaataat cattgcccgt
     1741 aaggctactg atgatgactg atactaaaac acagaattga ttgataaata gtgcctctgt
     1801 ataagaaaaa ttcaagagag aatggctcaa aaagaagata ttataaattc cacccaaagc
     1861 gccacccaag gaattaataa gcaagacagc aaagagcata aaaccaaagt ttttctgtcc
     1921 acttttaaga aaaacgagac gtaaatttcg gtaaattgtt aggaactggt ctttgataga
     1981 aagcttctca ttttttaagt tttcaccatc agcagatgac attgacaggc tcaatttgct
     2041 ttttcctaaa aagaggatag tggctgatac taggaaaaag caggcattga ttcccgcaac
     2101 gagagaaaaa ttgttgaccg atagagctaa gagccagact ccgaaagctt gaccaccaat
     2161 agctgaaata taggtgatga actgtgaaaa agaataagcc tccatcagat catcttcagc
     2221 tactttttcc ttaataagag gcatacgcag gccacctgca aaatcactga tgatatcact
     2281 aatgacattg atcaaacaca ggctagaaaa ggcaaagaga ctagcttgct gaacaactag
     2341 ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta tagaccatcc atttgacctt
     2401 gtccctcgtg taatctgccc gaatccctgc aaaaactgta aagagggtcg gaagaatcat
     2461 gacaatattc gccatagcaa cagcaaaaga tgcttgtgac aaggtcgatg catagacgat
     2521 aaagaccagg ttgaaaatcg aaacaccaaa agcattgaag aagcgtgata aagtcaaaat
     2581 tctataagct ggatttctaa acaatagttt catagataat ctccctcctt gttctaagtt
     2641 ctacatcaag aatagcttta gtatagcact tatgaatttg cgaaacgatt cttttgaata
     2701 tatgcaacaa acaaaatgag caaaaaaacg atagaacttt tgtaatgacc tgagagaggg
     2761 caacagttct atcgcttcaa attttttctt ggtttgcaga tattcaagaa tcgggagttt
     2821 ttctatagta ttcggcagat ttattacagc caagcatctc aaaaatacgg acagcatcct
     2881 ccatcttttt ctggccttcc ttgactctac cttgcttgct atcaaggaga ccttctgccc
     2941 acagataaac aattcggaaa taggtctcat tttccttgta gaaatgctct tcgataacac
     3001 gtttaaaata ataggcattg gtaaattctt cacactcaat actagctaaa aagccattca
     3061 atagtatagt atgaaaaagg tttcgattgc cagacatttc cattagaaaa tcagatttac
     3121 gtaccatttc tcgtacatat ctagtaaaaa gagaaacaga taaaaatgga gaactgactg
     3181 aaaataaatt gagttcatag attccccaga tctcggtaga aaacaaataa tcatgaagga
     3241 cttttccttc ctctgctgtt aagtctaccc tttcatctat gctcttcata taagacttga
     3301 taataatggc atttagaata tgtttctgtt tgttgtgaga atgggcatgc ttttatactc
     3361 cctgcgatat aagtcctcaa gaggtgctat attctttggt tccaagacat ctgtaatttc
     3421 ttttctcaac tcagaatctg tatcatactg gaaacctctt gccagaaaga ggatctcctc
     3481 cacactggca gatatatttt ccagagcaaa tagaaacttt tccaccgaaa gctcactctg
     3541 acctgtttca aaacgggaca acatagacgg cgaaaattgt cctccggttg cttgtctcag
     3601 tgagatattt cttgactctc gtaattgtct aaagactttt ccaatctgct ccatagactt
     3661 ccccttgatt ccgtattttc ttcattttat catatttttc agaaaattca tcaaaaactt
     3721 gccaaattgt cagaattatg agaaaataga ggatatttat cacgtggagg gactgctatg
     3781 agagacgata tcaaaatcaa tgaccgtgct ttggccttgc aagaccaaat tatcgaaaaa
     3841 ctagagaaag tttttgatac agatgtggaa ttggatgttt acaatctagg tctgatttat
     3901 gaaatcaatc tggatgaaac ggggctctgc aagattgtca tgaccttcac cgatactgcc
     3961 tgtgattgcg ccgaaagcct gcctattgaa atcgtggcag gtctgaaaca aatcgagggt
     4021 atcaaagata tcaaggttga agttacctgg tcgcctgctt ggaaaatcac acgaatcagt
     4081 cgctatggcc gtattgccct tggactacca cctcgttaag cagaccaatc acttttaaag
     4141 atgaaaaaag caagccgaaa atggcttgct ttttgatact caatgaaaat caaagggcaa
     4201 actagaaaac tagccgcagg ttgctcaaaa cactgttttg aagtt
//
LOCUS       DAVDHC010000073         3283 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVDHC010000073 DAVDHC010000000
VERSION     DAVDHC010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3283
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.074"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            72..1331
                     /locus_tag="VUR43_002239"
     CDS             72..1331
                     /locus_tag="VUR43_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET5413847.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     KAVKEALTEMLQSGTTTFNDMYNPIGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1407..1542
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1581..2081
                     /locus_tag="VUR43_002240"
     CDS             1581..2081
                     /locus_tag="VUR43_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET5413848.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2157..2525
                     /gene="rplL"
                     /locus_tag="VUR43_002241"
     CDS             2157..2525
                     /gene="rplL"
                     /locus_tag="VUR43_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET5413849.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2712..2882
                     /locus_tag="VUR43_002242"
     CDS             2712..2882
                     /locus_tag="VUR43_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413850.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2882..3133
                     /locus_tag="VUR43_002243"
                     /pseudo
     CDS             2882..3133
                     /locus_tag="VUR43_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
BASE COUNT         1037 a          591 c          719 g          936 t
ORIGIN      
        1 acacctacgg caaagtgaat ctgaagtggt ttgaagagag tacaacttgt cttttaaaaa
       61 aggagtctat aatgaaagtc tttcagcatg taaatatcgt gacttgtgat caaaatttcc
      121 atgtttatct tgatggaatc ttagcagtca aggattctca aatcgtctat gtcggtcaag
      181 ataagccagc gtttttagaa caagctgagc agattataga ctatcaggga gcttggatta
      241 tgcctggttt ggtcaattgt cacacccatt ctgcaatgac aggtctgaga gggatccgag
      301 atgacagcaa tctccatgaa tggctcaatg actatatctg gccagcagaa tctgagttta
      361 ctcccgacat gactaccaag gcggtcaaag aagccttgac agagatgctc cagtcaggaa
      421 caacaacctt taacgatatg tataatccca ttggtgtgga tatccagcaa atttatcagg
      481 tggtgaaaac ttccaagatg cgttgttatt tttctccgac tctcttttct tcagagacag
      541 aaacaactgc tgagactata agcagaactc gatccatcat agatgaaatc ttaaaatata
      601 aaaatccaaa tttcaaggtt atggtagcac ctcattctcc gtatagctgc agtagagact
      661 tgctggaagc gagtttggaa atggcaaaag agctaaatat tccgctccat gtccatgtgg
      721 cggagaccaa ggaggagtca ggaattatcc tcaaacgata cggcaaacgc ccccttgctt
      781 ttcttgaaga actgggttat ttagatcatc cgtccgtatt tgctcacggg gtcgaattaa
      841 acgagagaga aattgaacgc ttggcatctt ctcaagtggc tatcgcccac aatcctatca
      901 gtaacctcaa actggcatca ggaattgctc caattatcca gctccaaaaa gcgggagtag
      961 cagtcggaat tgcgactgac tcggttgctt ccaataacaa tctagatatg tttgaggaag
     1021 gaaggactgc agctcttctt cagaagatga aaagtgggga tgccagccag tttccaatcg
     1081 aaacagctct caaggtactg acaatcgaag gggctaaggt ccttggaatg gaaaatcaga
     1141 taggaagtct ggaagtcggc aagcaagcag attttctggt cattcaacca caagggaaaa
     1201 ttcatctcca acctcaggaa aatatgctgt ctcacctggt ttatgcagtt aaatctagtg
     1261 atgtagatga tgtttatatc gccggagaac aggttgttaa gcaaggtcaa gtcctgacag
     1321 tagaacttta aaagaaaaat tacgaaaaat tttaaaaaaa gtttgcaaaa atcttgcatt
     1381 ctttttttga ctatgctata cttatatacg gtttaaaaaa actgcctaag acagtagggg
     1441 agctcgactc ataaatatcc taccgaggac aaaacgtatc atgtaaaaag aagcgtattg
     1501 tactttcgtg tctaggtttg ggcgcgtttt tctttttgaa aaattcccca agcaaaataa
     1561 ttacggaggt gaacacacta atgagtgaag caattattgc taaaaaagcg gaactagttg
     1621 acgtagtagc tgaaaaaatg aaagctgctg catctatcgt cgttgtagac gctcgtggtt
     1681 tgacagttga gcaagataca gttcttcgtc gtgagcttcg tggaagcgaa gttgagtata
     1741 aagttattaa aaactcaatc ttgcgtcgtg cagctgaaaa agctggtctt gaagatcttg
     1801 catctgtatt tgttggacca tctgcagtag cattttctaa tgaagatgtt atcgcaccag
     1861 cgaaaatctt gaacgacttt tctaaaaacg ctgaagcact tgaaattaaa ggtggtgcaa
     1921 tcgaaggcgc tgtcgcatct aaagaagaga ttcttgcact tgcaactctt ccaaaccgcg
     1981 aaggacttct ttctatgctc ctttctgtac ttcaagcgcc agtgcgcaac gttgctcttg
     2041 cagtcaaagc ggttgcagaa agcaaagaag acgcggctta atcttaagct acacagcgta
     2101 gcctagctac gaaaaaaact attataaaat ttaaaactta tttggaggaa ataacaatgg
     2161 cattgaacat tgaaaacatt attgctgaaa ttaaagaagc ttcaatcctt gaattgaacg
     2221 accttgtaaa agctatcgaa gaagaatttg gtgtaactgc agctgctcct gtagctgttg
     2281 ctgcagctga tgcagctgat gctggtgctg ctaaagattc attcgacgtt gaattgacat
     2341 ctgcaggcga caaaaaagtt ggcgttatca aagttgtacg tgaaatcact ggtcttggtc
     2401 ttaaagaagc taaagaactt gttgacggtg caccagcact tgttaaagaa ggcgttgcaa
     2461 ctgcagaagc tgaagaaatc aaagctaaat tggaagaagc tggagcttca gttactctta
     2521 aataatagag tatcgcaatt tgattgcgga atccctattt accagtcttt gagagcgata
     2581 agcgattgat agaaactgat aaattgattt ggtttcctgc caaaaattct ttggcaggat
     2641 ttttgtttta ataaactttc gggggtagac actagattgt ctaccccttt ttttgtgttt
     2701 cggaggtaat tatgcaaaag gaaggacagt catcacgtca attcgtgaag agtcatctca
     2761 tgactatcat gggagttgat attgtaaaag caactcagtt agttgatgaa atggaacaag
     2821 taggtttaat ccgatttgat gaatttggaa atgttggaat tttagtcttg gagggacaat
     2881 aatgaagcgt attaccgcta atcaatatca gacatcagag cgttattata agctccccaa
     2941 acttttattt gagagtgaac ggtataagaa tatgaaactg gaggttaagg tggtttactc
     3001 agttttaaaa gatcggttgg agttgtcttt gagcaaaggt tggattgatg aggatggggc
     3061 tatttatttg atttattcca attcaaattt gatggcactt ttaggctgtt caaagtcaaa
     3121 attactctcc atgtgagttt gaagtaacat ttttagatga ttaccataaa aaacacaact
     3181 acccactatt ttacgagtcc tatcttcaaa acgttatgga attccttgaa agtcaagaca
     3241 taaagaatgg ggttgatgcc tttgtagatg atcatcaaaa tct
//
LOCUS       DAVDHC010000074         3089 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVDHC010000074 DAVDHC010000000
VERSION     DAVDHC010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3089
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.075"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(94..1380)
                     /locus_tag="VUR43_002244"
     CDS             complement(94..1380)
                     /locus_tag="VUR43_002244"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET5413851.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRT
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(1611..1847)
                     /locus_tag="VUR43_002245"
     CDS             complement(1611..1847)
                     /locus_tag="VUR43_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET5413852.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            2113..2894
                     /locus_tag="VUR43_002246"
                     /pseudo
     CDS             2113..2894
                     /locus_tag="VUR43_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3013..3086)
                     /locus_tag="VUR43_002247"
     tRNA            complement(3013..3086)
                     /locus_tag="VUR43_002247"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3050..3052),aa:Asn,seq:gtt)
BASE COUNT         1071 a          680 c          433 g          905 t
ORIGIN      
        1 aaagtttagg atatttgtta caacaagtta ggaggtcttc ttgtaaccgt ttatagtata
       61 cccgacctat cttaaacaaa tcttaaaaat ctcttaggac caaacacttt ctaaaatatt
      121 tgtttgttca cgaccaggac ctactgagaa agtagaaata cgaacgccaa ccaattcact
      181 cacacgacga acatagttac gcgcattctc aggaagatct tccaaattgc gaactccggt
      241 aatatcttct gaccaacctg gcaactcttc atagataggc ttgcaacgtt tcaattgctc
      301 aagactagct ggatagtagt caatacgttg accgtcaaga tcataggcca cacagatttt
      361 cacagtatcc aaaccgctca aaacatcaat agagttcaaa gaaaggttag taataccaga
      421 aacacgacgg ctatgacgca tcacaactga gtcaaaccaa cctacacgac gtggacgacc
      481 agttgttgta ccatactcat gacccacttc acggatacgt tctcccactt catcaaacaa
      541 ctcagttggg aaaggaccat ctcctacacg actcgtataa gctttacata cacctacaac
      601 cttgtcaatc ttgcttggac cgacaccaga accaattgtc acaccaccag ctacagggtt
      661 tgatgacgta acaaatggat aagtaccttg gtcgatatct agcataacac cttgtgcacc
      721 ttcaaaaagc acacgtttgc cattatcaag cgcatcattc aagataacag atgtatctat
      781 cacgtatttc ttgatttgtt gaccatattc gtaatattct tcaaaaatat catcgaaaac
      841 aatcgcttta ctgtcataca atttttcaaa aagacgattc ttttcagcaa ggttacgttc
      901 taaacgctca cggaaaatat ctttatctaa aagatctgca atacgaattc caacacgagc
      961 agccttgtcc atataagctg gaccaattcc cttaattgtc gtaccaatct tattgtcgcc
     1021 cttagcttct tcttgcaagc gatccaactc gatatgataa ggcaaaataa catgcgtacg
     1081 atcagaaata cgcaagttat cagttgttac accttcctca tgaagatagc tcaactcttt
     1141 tacaagagat ttaggattta caaccatacc attcccaatg acagatattt tttcagggaa
     1201 gaaaatccca gatgggatca agtgcaactt aaatttctta ccgtcaatca caatcgtgtg
     1261 accagcatta tcaccacctt ggtaacgtgc aatcacttct gcattcgctg aaaggaagtc
     1321 tgtaatcttc cctttacctt catcacccca ttgggtacct acaacaacaa ctgaagtcat
     1381 aatcttgtct gagccctcag gctcttcctt tctcacatac atggcaggac tctcacctgc
     1441 aattatatct tacaatttat tataataaaa aatcgccttt ttatcaagaa gaaacaatag
     1501 aaagatttgc tatttccaac tattaaaaaa tgatttagaa aaattactag ctatttacta
     1561 tcatctttcc ataaaagagt aaattagttc ggaaatttac taaaattacc tcaacaagaa
     1621 ataaaacccc gattcattac caatttttca agatacaaac gataagcaac acgataatgg
     1681 taaacaataa aatccttacg acaaccaatg ccatatctta ctaaataata aattaaaaat
     1741 ttaaaatgaa catgttccca gtcaaaatta tcaccaaatg taggaccata ctcttcttca
     1801 atactatcat agaaattagc catctgctca taaatttttt gtaacataat caaatactcc
     1861 ttttcttttt tataaactta ttctaacaaa aaattttaca cattcactat caattcctga
     1921 attgttaaaa taccagcctc aacaagataa aaataggaaa agttgacaaa atagaaacaa
     1981 atttgctacc taaatttcaa acaattaaag ttctaaaaag accgccttaa aacttttggg
     2041 taaatcctat taaaactata atatttttat ataggtatta tggttctgat tttctagtat
     2101 aaaaaaattc aaactagaat tctccttaga aagcgtcgat tcaagtgcta tcactgttca
     2161 aaaatgatgg tcgctgaaac ttctatcgtc aagaagaatc atcaaattcc ttgtatcatc
     2221 aaccaaaaga ttgctcagaa gctaattgaa aagacttcta tgaccgacat tgattatcag
     2281 ttgtctattt caactgtcat tcgcaagatc aatgattttc actttgagca tgatttttcg
     2341 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc agggagtgac tatttcaatc
     2401 gggagatgga gatgagcttt attgctcagg actttgataa gctcaatatc ataactgttc
     2461 ttgagagcag aacacaagcc atcatacgaa atcccatgaa tacaaggcta tcaagcgcta
     2521 ctggagctca ttcaacaaga tagtcagaaa ctgagtgata aacgatttta tcgccctact
     2581 tttcgtatgc acttgactaa taaagaaatt ctagataaac ttttgagcta ttcgaagact
     2641 tgaaacacca ctataatctc tatcagctat aatctctatc agctcttgct tttccacctc
     2701 tttttcagac tctgtttaaa accttcctca aagataaaga aaaaatcgtc aacggccttc
     2761 aattacctta ttccaacgcc aaactggaag ccaccaataa tctcatcaaa cttatcaagc
     2821 acaatgcctt tggttttagg aactttgaaa acttcaaaaa agaaaggacg aaatttgtcc
     2881 tttctcaagc ttagcttttc ttcaacccac tacagttgac aaagagccac tatttttggt
     2941 tcattttact ataacacgaa atagattatt attacataat aaaaaagagg tctaaacctc
     3001 ttaactaaat tactccgcca gtaggactcg aacctacgac atcatgatta acagtcatgc
     3061 gctactacca actgagctat ggcggatta
//
LOCUS       DAVDHC010000075         2560 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVDHC010000075 DAVDHC010000000
VERSION     DAVDHC010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.076"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(32..262)
                     /locus_tag="VUR43_002248"
     CDS             complement(32..262)
                     /locus_tag="VUR43_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413853.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(280..921)
                     /locus_tag="VUR43_002249"
     CDS             complement(280..921)
                     /locus_tag="VUR43_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET5413854.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(933..1613)
                     /locus_tag="VUR43_002250"
     CDS             complement(933..1613)
                     /locus_tag="VUR43_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET5413855.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVAIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            complement(1669..1866)
                     /locus_tag="VUR43_002251"
     CDS             complement(1669..1866)
                     /locus_tag="VUR43_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413856.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            complement(1866..2072)
                     /locus_tag="VUR43_002252"
     CDS             complement(1866..2072)
                     /locus_tag="VUR43_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5413857.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2082..2396)
                     /locus_tag="VUR43_002253"
     CDS             complement(2082..2396)
                     /locus_tag="VUR43_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413858.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
BASE COUNT          870 a          522 c          421 g          747 t
ORIGIN      
        1 acaaaaatcc gatgaacttc accggactct tttattttga atttttgcct gctttacgct
       61 tttcagcgat ttcggctgcc tttcgaggca agacaatttc cgttatgtaa gccgtcccaa
      121 aacgcagtac acctgcaata ggagcaaaga caactgctag atagttatag aagaaatcgc
      181 ctttgaaggc ataagctagc gctccaatga tgaaaaatag aacgactgcc tgaatcactg
      241 ctaataaaat tactcgtttc atgtgacctc ctgactctat tatagcatga gaatcatcaa
      301 aaagccgact aaattattca aagcgtgaag agaaatactg tagaccagac cttttctgct
      361 aatgtaagcc aaacccaaac taaaaccaag gctaaaatag acaaaaaatt gttgcacatc
      421 acctggaaaa tgaatcaagg caaatagaag actagatacc agaagaaaaa tcagggttcg
      481 tttactattg tcctgcttag gaaagagata gcgtgctaac atccctctaa aaacaatctc
      541 ttccgtcaaa ggagcaaaaa taaccacagc aaagaatgag aaaagtggtt gagacaaggt
      601 caagtctgtc gctatttgct gatttactga aggatcatct ggcaagaaga attgaacgac
      661 cagagataag aaccaaacca agacaggaag ccaaataaat cgattaaagc cgctcttctc
      721 aatatgaaca ggagccttct gataccattt gtaaatgccg tacacatata ctccagccaa
      781 ggccacatag agtagagtaa cagcataggg tgaagcgcct aaagcaagcg acgcagtcgc
      841 gagcccctga ataaagccat agataaataa aaaggataga agggctagaa gaatccagcc
      901 aaggttttta agtaatttca tagataactc ctttatttga aataacgttt taccataggt
      961 aactgcatca cattgatata aacatggatg gctcctacaa gcaagaaagc tagtaactga
     1021 atctctcctg tcaagaaaga aatgataata agaaaaatat ataaggctgg taagacatat
     1081 tggtgtaatt ggaataaaat tcgaaaactc tgttccaaat tagcctgacg ctccccttca
     1141 tcataagaat ttatatagtt caagacatcc tttggtgtag cgaaaaattc caaatcaaac
     1201 tgacgaacaa tcgcaatggt tttaaaaaga gatttttgag cgactaagaa taccacaaag
     1261 agtaagaaag aaaggaaaaa tgtttgaggg tttgtatgca atataatcac ctcacttaat
     1321 gaaataaaaa tagccaatgg aatcgctaca cctgtaatat taaaagcaat ggttccaaac
     1381 tcaagattcc gatacatttg cacataatag gtttcattca gatcgtcatc catttcctct
     1441 tgatacaagg aatgaaattt tctgcttttc tttaagaaat tgaaagtcaa aaacatacta
     1501 atgaaaccta tcagtaaaca aatagctgat atccatggca tcaaggcttt tacatctaaa
     1561 ataatttcgt gggattcgac acgtgcctta aacatcccta caaacatgcc caagaacccc
     1621 ccaagacaat agacatcaaa aataacaatc tacgtttctt tttcatattc attctccttt
     1681 ttcacttgct agatttttgg atttcttttc aatccattca attactggga tgagagcaaa
     1741 gtagacccaa acaaattggt cgctttgata gggattaaac cagcttaggt ccatcccaat
     1801 cagtagaaat acgctgacta ataaagctat gaccactaca taataaatca ctttatactt
     1861 gttcatcact cgtcctcctc caaacgaaat accgattcga ctgtttcgtt gaaaatttga
     1921 gatattttca gggcaatgat aatggatggg gtgtactcat cccgttctag taggctaatg
     1981 gtctgtctgg aaacccctgc cagtttggct aggtcggttt gattgagacc atcgcgagct
     2041 cgaagctctt ttagacgatt ttttagttgc atgttacaca cctactctcc gtcaaattca
     2101 acggtttgga tatcctcaat acgttgcaac ttgaattttt cttttcccgt attatctaca
     2161 cgtcgtagct ttacccattc ctcatcaaca tccacaactt cccagttatc tggcccaata
     2221 tacactcccg ttataattgg ttcctttcca atcatttctt gtaataatct cgacatttct
     2281 gcgtttcctt tctcttttcg ctcaagtctt ttgattttat tctctagttt cttgattttt
     2341 ttagaattat tagaataaaa gaaaatcata aatagtataa atcctagtac ccacattata
     2401 actcctttct gcttcctatt tcttaacttg aattcattgt aacatatctt tttctttttg
     2461 acaagtatag ttgtcaaaaa aaatatgatt tttgtcattt tgcaaaagaa aaaggtcagg
     2521 agtaggttcc tgaccacttt atctatcatt aatactcttc
//
LOCUS       DAVDHC010000076         2176 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVDHC010000076 DAVDHC010000000
VERSION     DAVDHC010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.077"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            152..565
                     /locus_tag="VUR43_002254"
     CDS             152..565
                     /locus_tag="VUR43_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET5413859.1"
                     /translation="MLANGIKLAFSETKGNYQNLVGLKEVPEFGIEPEKVENTTLADT
                     VKKYEFGIGDAGELEYKFAYNNSSATAPYRVLRKAADGKKKLYFEQTYPDGTKVTFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSNLTFTDGVGG"
     gene            570..950
                     /locus_tag="VUR43_002255"
     CDS             570..950
                     /locus_tag="VUR43_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413860.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVVE"
     gene            989..1339
                     /locus_tag="VUR43_002256"
     CDS             989..1339
                     /locus_tag="VUR43_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413861.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIKSYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQRQALLLHKERMRDFAE
                     RHNRKRKEEINGNS"
     gene            1326..>2176
                     /locus_tag="VUR43_002257"
     CDS             1326..>2176
                     /locus_tag="VUR43_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413862.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RSITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQ
                     IRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVT"
BASE COUNT          671 a          391 c          531 g          583 t
ORIGIN      
        1 tcaatcagat ttttgagtct ttaggtttgc gaagaaccga ctgccaagac gtgccagacc
       61 cgtctcattt gagacataag gtcatgcgtt ttgaaggtgt cgttgattta gactcagagc
      121 ttgtttttca atttagaatg gagaattaaa catgttagca aatggaatta aattggcctt
      181 tagtgaaacg aaaggcaatt atcagaatct tgtagggctt aaggaagtac ctgaatttgg
      241 tatcgaaccc gaaaaagtag agaatactac ccttgcagat acagtgaaga agtacgagtt
      301 tggtatcggg gacgcaggag aacttgagta caagttcgct tataataatt caagcgcaac
      361 agctccttac cgtgtattac gtaaggcagc agatggtaag aaaaaacttt actttgagca
      421 aacatatcca gatggtacta aggtcacttt tgaaggtcaa gtatctgtta agcttggcgg
      481 tggcggtgtc aatgccgtta tcgagttcac acttaagatt gctttgcagt ctaatcttac
      541 atttactgat ggtgttggag gttaattaaa tggcgttaaa atacacaact tggaaagtta
      601 ctgacgaaaa agagttgaag ctacgtttga catctcatca agctgcaact gtggaagaaa
      661 aaatcggcat gaacttgctg aagattttca tgcctgaagc tggcgaagag ttcactttac
      721 cgcctttgaa agttatgttg ttgttagttc acggcgcctt gcagcagtac gaacatgggt
      781 attcctttga agatgtctac gacctatacg atgaatacgt ggataacggc ggagaccaaa
      841 cgacattcat gacagaggtg ttgatgccgc tatttgaagt atcgggtttt actccacgag
      901 gaagcaagga caagaaaact tccaagaaga aaatgacagt agtcgagtaa tcttaacggt
      961 aacgcagatt attgagaggc tttatcctat gtttttagac atcgggggca agcctcttga
     1021 tttttgggat ttaacggtgc ttgaaatcag ggaaatgata aaaagctaca accgtgtcaa
     1081 aatccaagag cgtaaagaaa agattattga ctcatacaga ctttcgcaga tgatatccaa
     1141 ccacgtttct ttattgttat ccaaagatgc caaggccttt gagttctggg aatatgcgcc
     1201 tgagttgttt gtagaagaac aacaagcagt agaacaggaa cgacagagac aagcgctttt
     1261 gttgcataag gaacggatgc gtgattttgc agagagacac aatcgaaaaa ggaaggagga
     1321 aataaatggc aactcttgat gaattgaagg tcatgattga cgctgagata gcgcctttca
     1381 ggaagaagat gaaagaagtt gagaatcagg tcaaaggaac atctgaccaa gtgaaaaatg
     1441 ccactgctaa agttcgtgaa cagtcgaact caatcggtag tgcgtttggt aagctggcta
     1501 agttcgctgg ttttgcaatc cttggtaaga aattacttga tgttgggatg tattcaacgc
     1561 agacggctct tgaagtatca gcgtctatga accaaatcaa gcgacagatg ggagagagtt
     1621 cgcaatcttt cttaaaatgg gttaacgata acgccaacgc tatgaatatg ggggtgggtg
     1681 aggctactaa ctacggtgcg gtctactcaa acttattttc tgggtttatc aaagatacca
     1741 acaagctaag cgcctatacc gctaagatgt tgcagacatc ggcagtggtt gctgaaggct
     1801 cagggcgtag cattacagac gttatggagc ggattcgctc aggtttgcta gggaacaccg
     1861 aagcgattga ggatctagga atcaacgtca atgtggctat gattgagtcc actgaagcct
     1921 ttaagaagtt cgcaaacgga caaagctggc aacaattaga ctaccaaacc cagcaacaaa
     1981 tccgccttat ggctattctg gaacaggcta cagccaagta tgggaatacc ttgtctaatt
     2041 ctgtaaatgg tcgtatcagc ctgtttaagt cgctgatgaa ggacgcagca ttgaaccttg
     2101 gtaactctat gttaccgatt atcaatgcca ttatgcctgt cttgaactct tttgctatgg
     2161 ttttgaagaa cgtgac
//
LOCUS       DAVDHC010000077         1860 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVDHC010000077 DAVDHC010000000
VERSION     DAVDHC010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.078"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VUR43_002258"
     CDS             complement(3..968)
                     /locus_tag="VUR43_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET5413863.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VUR43_002259"
     CDS             complement(1086..1499)
                     /locus_tag="VUR43_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET5413864.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWISEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VUR43_002260"
     CDS             complement(1496..1732)
                     /locus_tag="VUR43_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET5413865.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          543 a          362 c          275 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 ataccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagcctc
      241 tggacttttc caactaacgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 tagtttctta aatgaatttt cgtacgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaatccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga ggcttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaaggacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcaaata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVDHC010000078         1801 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVDHC010000078 DAVDHC010000000
VERSION     DAVDHC010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1801
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.079"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..213
                     /locus_tag="VUR43_002261"
     CDS             <1..213
                     /locus_tag="VUR43_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET5413866.1"
                     /translation="DVHCDAVMVKDVNEDLMKGYDIFTPIAATDLGFEPGIPVIEAGP
                     ILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            261..1736
                     /locus_tag="VUR43_002262"
     CDS             261..1736
                     /locus_tag="VUR43_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET5413867.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          504 a          367 c          366 g          564 t
ORIGIN      
        1 gatgttcact gtgatgcagt catggtgaaa gatgtaaacg aagaccttat gaaaggttac
       61 gatatcttta caccaatcgc tgcaacagac cttggttttg aaccaggtat cccagttatc
      121 gaagctgggc caatcttatt ccgtatccca gcaatgagcg ctccagtatt tgacaatatt
      181 gaagcagcta ttaaagaaca cggattaagc taattctaat ttgttaacat tcatataaca
      241 taaaaaaggg aggaactgtt atggatgcaa tctttgacct aatcggaaag gttttcaatc
      301 ccattttaga aatgggtgga cctgtcatca tgttaatcat tttgacagta ttggctttac
      361 tttttggagt gaaattctcc aaagcgcttg aaggtggtat caaacttgcc atcgctctta
      421 caggtatcgg tgctatcatc ggtatgctaa atggtgcttt ctcagcatca cttgcaaaat
      481 tcgttgaaaa cactggtatc caattgagta ttaccgacgt tggttgggca ccactcgcaa
      541 caatcacttg gggttctgct tggacactat acttcttgct catcatgttg attgtcaacg
      601 tagtgatgct tgctatgaag aaaaccgata cacttgatgt cgatatcttt gatatctggc
      661 acttgtctat cacaggtctc ttgattaaat ggtatgctga taacaatggt gtgagtcaag
      721 gggtttcact ctttattgct acagcagcta tcgtccttgt cggtgtgttg aaaattatca
      781 actctgactt gatgaaacct acatttgatg accttcttaa cgccccaagt tcatcaccaa
      841 tgacatcaac tcacatgaac tacatgatga acccagttat catggttttg gataagattt
      901 ttgaaaaatt cttcccaggc cttgataaat atgactttga tgctgctaaa ttgaacaaga
      961 aaatcggttt ctggggatct aaatttttca tcggtttcat ccttggtatc gttatcggta
     1021 ttatgggaac tccacatcca attgcaggtg ttgcagatgc agataaatgg cgtcttgtta
     1081 tcaaaggatg gttgtctctt ggtttgactg ccggtgtatc tttggaactc ttctcactta
     1141 tcggttcatg gttcatcgca gccgtagaac cactatcaca aggtattaca aacgttgcta
     1201 ctaaacgtct tcaaggacgt aaattcaata tcggtcttga ctggccattc atcgctggtc
     1261 gtgctgaaat ctgggcttgt gccaacgtac ttgcaccaat catgttgatt gaagcagtgc
     1321 ttctttcaaa agttggaaat ggtatcttgc cacttgcagg tatcatcgct atgggtgtta
     1381 ctccagctct cttggttgta actcgtggta aattgctccg tatgattatc ttcggaacac
     1441 tcttgttgcc actcttcctt ctttcaggta cacttattgc accatttgca acagaacttg
     1501 ctaaaggtgt aggtgccttc ccagaaggtg tgagccaaac tcaattgatt actcactcta
     1561 ctcttgaagg accaatcgaa aaacttcttg gttggacaat tggtaacact acaactggtg
     1621 atatcaaagc aatccttggt gcagtagtct tccttgtatt ctatatcggt atctttgctt
     1681 ggtacagaaa acaaatgatc aaacgtaacg aagagtacgc agcaaaagca aaataatgcg
     1741 ctcctataaa atataaactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt
     1801 t
//
LOCUS       DAVDHC010000079         1785 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVDHC010000079 DAVDHC010000000
VERSION     DAVDHC010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1785
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.081"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(1..242)
                     /locus_tag="VUR43_002263"
                     /pseudo
     CDS             complement(1..242)
                     /locus_tag="VUR43_002263"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(280..612)
                     /locus_tag="VUR43_002264"
     CDS             complement(280..612)
                     /locus_tag="VUR43_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET5413868.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADSISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEHYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKNS"
     gene            complement(625..1398)
                     /locus_tag="VUR43_002265"
     CDS             complement(625..1398)
                     /locus_tag="VUR43_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET5413869.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAN
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
BASE COUNT          608 a          328 c          188 g          661 t
ORIGIN      
        1 aggcaacaga accaaaaatt taaacaagct gacacaacta aatgtctatt cttgccgatt
       61 ttttcgtaat aatgtgtacg ctctagtatt tcttttccga ccatgtaaat ataatctatt
      121 tcaaaaagat gatataaatt accaatcagc gttatctcat aggacttcca tcgttccttc
      181 tggaataaat agtcatatac taaatttaga tcatctctac taactacatg attacaatct
      241 agctgatttc ataatccctg aaccataatt gtatttattt tatgagtttt tcccactctt
      301 ctcaaaaagt ttttgttgct tattttttat tacctccaat cctttaatat tcaaactata
      361 aaaatttgga gataaattaa ccaaaaaatc atcacgctcc gatcttttat aatgttctaa
      421 gtgattacaa aaattctcta tcgaaacatt gatatttgat aataattcaa aaaatgttga
      481 aagagaaatt tcattttctc ccctttcaaa tctagaaagt tgagattttg atatagaatc
      541 agctgcagca tactctaaag aatatccgtt taattttcta aaatatcgaa aagcttctcc
      601 gtaatttttc acactttcat tcccttaact ttcttttcga gcgataaaca taccatattc
      661 tttaggaatg atcaacatac cattattaaa ctcactttcc aatcttttac gtattatttc
      721 ctcttctagt gaacctattt ctgaaattcc tttaaacgat tggatgtatt taactaggtc
      781 atctatacta gttacctgta actcatcatc atagagtaat gtatcgacag agttaaaata
      841 cctactcagg taccttttac cattttgtaa agtaaacgtt ctattttcta aatcttgatt
      901 aacctcatct ttaaataaat ttgccaaata atttacaact ccattttcac caaatgtagc
      961 acagtaaaaa attcctccgg tttttaagac cctattcacc tcagagagag ctttaggaat
     1021 atcattcaca tgatgtagaa gcatattagc aataacaata tcaaaagttt cattctcaaa
     1081 agaaatcttt tgaatatcca ttatctcata attgacattg tttctatttc caatcactga
     1141 cttcgttgat tttaccatat ctttagaaaa atctgtaaca atcaactgct tcattttatc
     1201 tatagaatca ctattacttt tccacaattc tcctgtacca catcccaatt ctagaacctt
     1261 tacttcatca gtgatttggt agttagaaaa tatccaatta ttaaatccca atttattttt
     1321 tgaatacttc ttatgcaatt ctactcgaat atcaagatta tcatgacttt tatattgttc
     1381 aattacttta tcaatcattt taaatgacct ccactctata atttggcatt atatcacaag
     1441 aataaagata gtgttaaata agttgtataa atgcaaaaaa ggaatattcc gttatagcag
     1501 agttgtaaca catttctata aagaaattta ttcctacgac tcagtttggc atgcttaact
     1561 tcctaactca aaaacaaagc atcgattaat ttatccgttc ttcttttgaa acagatttga
     1621 actgataatt gctcgtttta atttaagaag ctcttttgag caaaacttca tttttttaag
     1681 agtccaacaa tttctgtcta tcgcttttct actagcaaaa aaaactacct tgaggcaagt
     1741 tttcatttat atatctaatt tcgtaatagt atagtaaaat gaaat
//
LOCUS       DAVDHC010000080         1631 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVDHC010000080 DAVDHC010000000
VERSION     DAVDHC010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1631
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.082"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..480
                     /locus_tag="VUR43_002266"
     CDS             <1..480
                     /locus_tag="VUR43_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HET5413870.1"
                     /translation="TVDTQENVDTVQEEKHERTFTRAEIGKMLSAERSKWEAEQEAKE
                     NEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAKAMLSERDLPVELVNV
                     VDLTNAETVSESITSIQKAWEESVQKGVSERMKGSAPIKNAQTVQQEVTEKWRKDFL"
     gene            503..1528
                     /locus_tag="VUR43_002267"
     CDS             503..1528
                     /locus_tag="VUR43_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HET5413871.1"
                     /translation="MAFEELNTAESRKKHLGIIEDVLAVNSYSTPLVTSSDAVTLQGR
                     SFTVATGNTTELKDYKRNKDNEFDHVEVEEKVYTLDEEKYWGRFVDQLDERDSNGQVN
                     INYVIARQAAEVVAPYLDELRFGAALGNVSDNVAMGKTAGANNAYNAVLDVSEKLDEL
                     GITKERLLFVTPSFYKAIKSEIVRLPHGDADKKVLGKGYVGELDDYTVYKVPSKFLKG
                     VNALATAPGVVTSPVQVDNTKYNDNIPGRFGELVEQLLYTGAFVLEHFKKYIITIADS
                     KPAAKPSTQGKVVNRAKAWKTGTAYKEDDTVTHEDKVYVAIKDITSSTNAPGSDSANW
                     KEKTGKK"
BASE COUNT          569 a          296 c          370 g          396 t
ORIGIN      
        1 actgtcgaca ctcaagaaaa tgttgataca gtgcaggaag aaaagcacga acgaactttc
       61 actcgtgctg aaatcggtaa gatgctatct gccgagcgct ctaaatggga agctgagcaa
      121 gaagccaagg aaaacgaagc taagaagctt gctaagatga acgctgatga aaaacagaaa
      181 tatcagttgg atcagcgtga gcaagaacta gctgaccgtg aaaaggctat tgctcgtaag
      241 gaattgaccg cagaggctaa agcaatgcta agtgaacgtg acttacctgt tgagttagta
      301 aatgtagtcg atttgacaaa cgcagagacg gtatctgaat ctatcacctc tatccaaaaa
      361 gcatgggaag agtcagttca gaagggagtc tctgaacgta tgaaaggtag tgcacctatc
      421 aaaaatgcac aaacagtcca gcaagaagtc acggaaaaat ggcgtaaaga cttcttgtaa
      481 taaaagaaaa gaggaaaaat aaatggcatt tgaagaatta aacacagcag aatcacgcaa
      541 gaaacatctt gggattattg aggatgtact tgcagtaaat tcatattcaa caccacttgt
      601 gacatcaagc gatgcagtaa ccttgcaagg tcgctctttt acagtagcaa ctggtaacac
      661 aacagagttg aaagactaca aacgtaacaa agacaacgaa tttgatcacg ttgaagttga
      721 agaaaaggtt tatacccttg atgaagaaaa atactggggt cgtttcgtag atcaattgga
      781 cgaacgtgac tctaatggtc aagtgaatat caattatgtt attgcccgtc aggctgcaga
      841 agtagtcgct ccatatcttg atgaactacg ttttggtgca gcacttggaa acgtaagtga
      901 caatgttgcc atgggtaaaa cagcaggagc gaacaacgct tataatgcgg ttcttgatgt
      961 gtctgagaaa cttgatgagc ttggaattac aaaagaacgc ttgctcttcg tcactccaag
     1021 tttctacaaa gcgatcaagt ctgaaatcgt tcgtctacca catggtgacg cagataagaa
     1081 agtccttgga aaaggatatg ttggtgaatt ggatgattac acagtctata aggttccttc
     1141 taaattcctg aaaggtgtta atgcccttgc tactgctcca ggtgttgtta catctccagt
     1201 acaagtagat aatactaagt acaacgataa cattccaggt cgatttggtg aattggtaga
     1261 gcaattgctt tatactggtg catttgttct tgaacacttc aagaaataca tcatcacaat
     1321 tgcagattct aagcctgctg ctaaaccatc tactcaaggt aaagttgtaa accgtgctaa
     1381 agcgtggaag actggaacag cctataaaga agatgacacg gtaacgcatg aagacaaagt
     1441 ctacgttgct atcaaagaca tcactagctc aaccaatgca ccaggatctg actcagctaa
     1501 ctggaaagaa aaaactggta agaaataggt ccgagttatg aaatttaaaa tcaaacaaga
     1561 tttctatgat tgggaatcaa atgtgaaacg actggcagga gaggaacttg agattactga
     1621 ggagcgctat g
//
LOCUS       DAVDHC010000081         1533 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVDHC010000081 DAVDHC010000000
VERSION     DAVDHC010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1533
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.083"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..1321
                     /locus_tag="VUR43_002268"
     CDS             <1..1321
                     /locus_tag="VUR43_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413872.1"
                     /translation="ETIYLNTLYAKDFVVNSGKTIAQLGKTALELGKSALAWTAHAAK
                     MGLATAAKFAHSVATGVATAATWAFNAALAVLTSPITWIIAAIAALIAIGVLLYQNWD
                     TVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTKLQEIFEPIGQWFGEKFQQAWDAIV
                     NIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQRWADVTSALANIGAWFTDMFQKAW
                     TGLTNIFSKLGSWFGERWADVTNALSSVSNWFGEMFTNAYNAVKDAFSSIGDFFKGVW
                     DTVKSIFVNAGQMVGEAVGGAFKSAVNAVLGTIENVVNGFIGMINGVLGVVRNLPGLG
                     WVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEAVVPLENTGFIQTLGRVVSSAVVNA
                     MAGVSPQGGFSGDGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
     gene            1330..>1533
                     /locus_tag="VUR43_002269"
     CDS             1330..>1533
                     /locus_tag="VUR43_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413873.1"
                     /translation="MAQLTINGVAVKPPKYFQVGIQDIDGETGRNANGDMMRDRITTK
                     RKLDCEWGMMTQGELSQLLHAVSS"
BASE COUNT          428 a          282 c          401 g          422 t
ORIGIN      
        1 tgaaacaatc tatttgaaca ccttatatgc aaaagatttt gtggtcaatt caggtaaaac
       61 aattgcacag ctaggaaaaa ctgctttaga acttggtaaa tcagctctag catggactgc
      121 tcatgcagcg aaaatgggat tagcaaccgc ggcgaaattt gcacattctg ttgcaacagg
      181 agtcgctaca gctgcaacat gggcttttaa tgcagcgtta gcagttttga caagtccaat
      241 aacatggatt attgcagcaa tcgcagcttt gattgctatc ggtgttttgc tctatcaaaa
      301 ctgggacacc gttgttgagt ttgctaaaac tgcatggcaa ggactatgtg attttatcag
      361 tggtatttgt caagcgattg gcgaattttt cagcggtcta tggacgaaac tacaagaaat
      421 ctttgagccg ataggtcaat ggtttggcga gaaattccag caagcatggg acgccattgt
      481 aaacatattc tctggcatcg gagagtggtt ctctggtgta ttccaaggtg catgggacgc
      541 tatcgttaat atcttcacac caatcggctc atggttcgga caacgttggg cagatgtgac
      601 tagtgcgttg gctaatatcg gggcatggtt tactgacatg ttccaaaaag catggactgg
      661 cttaacaaac atctttagca aactaggttc atggtttggc gagagatggg cagatgtgac
      721 taatgcgtta tccagtgttt caaactggtt tggtgagatg ttcactaatg cttacaacgc
      781 agtaaaagat gcttttagtt ctattggcga cttctttaaa ggcgtttggg atactgttaa
      841 aagtatcttc gtaaatgctg gtcagatggt cggagaggca gtaggtggag cgtttaagag
      901 tgcggttaat gcggttcttg gaacgattga aaatgtagtc aatggcttca tcggaatgat
      961 taatggagtt ttaggcgttg tcagaaactt acctggtcta ggatgggttg gtagtgtaag
     1021 cacagttagc ctccctcgtc ttgcccgtgg tggtatcgtc gatagtccaa caatcgccat
     1081 gattggtgaa gctggtaaag aggcggtcgt accacttgaa aatacaggat ttatccaaac
     1141 acttggacga gtagtcagca gtgcggtagt aaatgccatg gctggtgtta gtccacaagg
     1201 tggattctct ggcgacggcg acatcgttat ccaaatcgca ggccatgagt tcggacgggt
     1261 agccatccaa gaaataaaca aggaacatga acgagcaggt caaaccttgc tcaagattta
     1321 ggaggttaaa tggcacaatt gacaatcaat ggggtggctg tgaagcctcc caaatatttt
     1381 caagtcggta ttcaagatat cgatggagag acagggcgta atgccaatgg cgacatgatg
     1441 cgtgaccgta tcacgaccaa acgcaaacta gactgtgaat ggggtatgat gactcaggga
     1501 gaattaagtc agcttttaca tgctgtatca tct
//
LOCUS       DAVDHC010000082         1520 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVDHC010000082 DAVDHC010000000
VERSION     DAVDHC010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.084"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..>1520
                     /locus_tag="VUR43_002270"
     CDS             <1..>1520
                     /locus_tag="VUR43_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HET5413874.1"
                     /translation="TAEELASRIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYTATI
                     DSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFYAKA
                     NKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQEGT
                     IWIWMPKFEISDVDTSYSEAPEDIEGQISTVESNFKQRADSLEAGVSRLTEGLRTKAD
                     ISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNVTKDKASKSE
                     LTQTAEELSSKIASVQVGGINLLRNTASLLIGDRSKGCWMSASGGNGRAISVEVLDPP
                     KKMIKNMIRVIENTNGGNKDLTQLVRLRIGEKYTISCYARIASDSPNANVNLLFRSWA
                     NNTDLNRKFQKSISHKNWQKYSFTFTADAIENSIQFGQSGAGIIEICAPKIESGTLAT
                     DYSEAPEDIEGQISTVESTFKQRANSLDAGVSRLTEGLRTKVDISALNVTAENIRQS"
BASE COUNT          506 a          276 c          351 g          387 t
ORIGIN      
        1 acagctgagg agctggctag tcggattgcg agtgtgcagg catccggtcg aaatctattc
       61 ttgaactcac tattcaagca ggatattcca aaaacaggaa tttggacaac gagtacatat
      121 acggctacta tcgatagcga aagtaagtat cttggacaca aggctcttaa aattataggt
      181 ttgaatccat ctggccgtga tggaggtaat cccaaggtta cttatccagc tctgggtcaa
      241 ttcgggaaag taattcccgg aagtacgact aatcaagatg taaccattag tttttatgct
      301 aaggcaaata aaaatggaat aatgctaaga tctcgattag ggaatatcgg atataaaact
      361 ggaaatgtga cattgtcgac agaaattaag cgatatgttg tccatattcc aaaaggttgg
      421 acaaacgaat ccaagcagac cacaaatgaa tggttgttca atttcaacca ggaaggaacc
      481 atttggattt ggatgccgaa gtttgaaata agcgatgtag atacttctta ttcagaagct
      541 cctgaagata tagaaggtca gatttcaaca gttgaatcca actttaaaca gcgtgctgat
      601 tcactcgaag ctggtgtaag ccgtctgact gaagggctta gaactaaagc cgatatcagc
      661 gcactcaacg tgactgctga gaatattagg caatctgtga agagtcttga gacagacacg
      721 cagaacaaac taaatcagaa gttgagtcag gctgaatttg aggtgcgagc tggctctatt
      781 cgtcaggaaa tcctgaacgt aaccaaggat aaagccagca agtcagaact tacgcagaca
      841 gctgaggagc tctctagtaa gatagcgagt gtgcaggtcg gaggaatcaa cctcttgcgt
      901 aatactgcga gtttgttgat tggcgatcgt tcaaaaggat gttggatgag tgcaagcgga
      961 ggaaatgggc gagcgattag cgtagaagtt ttggatcctc ccaaaaaaat gataaaaaac
     1021 atgattcgtg ttattgaaaa tacgaatggt ggaaataaag atttaactca acttgttaga
     1081 ttgcgaattg gtgaaaagta cacgatttct tgttatgcaa ggattgctag cgatagccca
     1141 aatgcaaacg tgaacttgct atttcgttcg tgggcaaata ataccgattt aaatcgcaaa
     1201 tttcagaaat ccatctctca taaaaattgg caaaaatatt catttacatt tactgctgat
     1261 gcaattgaaa attcaattca atttggacaa tctggcgcag gaattatcga aatatgcgct
     1321 ccgaaaatcg aatcaggaac gttagcgact gattacagcg aagctcctga agatatagaa
     1381 ggtcagattt caacagttga atcgaccttc aaacaacgag ccaactcact cgacgctggt
     1441 gtaagccgtc tgactgaagg ccttagaact aaagtggata tcagcgcact caacgtgact
     1501 gctgaaaata ttaggcagtc
//
LOCUS       DAVDHC010000083         1379 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVDHC010000083 DAVDHC010000000
VERSION     DAVDHC010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.085"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            220..>1379
                     /locus_tag="VUR43_002271"
     CDS             220..>1379
                     /locus_tag="VUR43_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HET5413875.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFR"
BASE COUNT          403 a          308 c          255 g          413 t
ORIGIN      
        1 tatctttgag gaaggtttta aagacagtct gaaaaatagg atgaacctgc ttaaccccaa
       61 ttattcaccc caaatctaaa aaccatccag aatccttgcc ttagcttaga tcctggatgg
      121 tttctttttt cacccaatgg gtgtttttta ctagacaaaa aagagtttcc cctttatggt
      181 ataagtgtag aaaaaaacac aaaaagaaag gaaactcaca tgaacagttt accaaatcat
      241 cacttccaaa acaagtcttt ttaccaacta tctttcgatg gaggtcattt aacccagtat
      301 ggtggtctta tcttttttca ggaacttttt tcccagttga aactaaaaga gcggatttct
      361 aagtatttag taacgaatga ccaacgccgc tactgtcgtt attcggattc agatatcctt
      421 gtccagttcc tctttcaact gttaacaggc tatggaacgg actatgcttg taaagaattg
      481 tcagctgatg cctactttcc aaaattgttg gaaggagggc agcttgcttc acagccaacc
      541 ttatcccgtt ttctttccag aactgacgag gaaacagtcc atagtttgcg atgcctcaac
      601 cttgaattgg tcgaattctt tttacagttt caccagctaa accaactcat tgtagatatc
      661 gattctaccc atttcacaac ttatggcaag caagaaggtg ttgcttataa cgcccactat
      721 cgtgctcatg gctatcatcc tctttatgct ttcgagggga agacaggtta ttgtttcaat
      781 gcccagcttc gtcctggtaa tcgttattgt tctgaagagg cagacagctt tatcacacct
      841 gttttagaac ggtttaatca acttctcttt cgaatggata gtggctttgc gaccccaaaa
      901 ttatacgatt taattgaaaa aacagggcaa tactacctca taaaactcaa gaaaaatact
      961 gttctgagcc gtcttggaga cctttccctc ccttgcccac aggatgagga cttaaccatc
     1021 ttgccccact ccgcctactc agaaactctc tatcaagcag gatcttggtc gcacaagcgt
     1081 cgtgtctgcc agttctctga acgaaaagaa ggaaacttgt tctacgatgt tatttctctc
     1141 gttacaaata tgacgagtgg aacaagccaa gaccagtttc agctttatcg tggacgtggt
     1201 caagccgaga atttcatcaa ggagatgaag gagggatttt ttggcgataa aacggatagt
     1261 tcaaccttaa tcaaaaacga agttcgtatg atgatgagct gtatcgccta caatctctat
     1321 ctttttctca aacatctagc tggaggtgac ttccaaactt taacaatcaa acgcttccg
//
LOCUS       DAVDHC010000084         1271 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVDHC010000084 DAVDHC010000000
VERSION     DAVDHC010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.086"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            130..>1271
                     /locus_tag="VUR43_002272"
     CDS             130..>1271
                     /locus_tag="VUR43_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HET5413876.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGDYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQISGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKARNDTQYS
                     YEGTITKQIKQQDGIEAKIQAQIEAADKDFDQKVDKIKKDFNDQVEL"
BASE COUNT          390 a          244 c          306 g          331 t
ORIGIN      
        1 cagaccccat ggatggccaa gtcacaaaga ctttctatgt cggtgatagg acagctccta
       61 gctatacctt tactgagaag tttaaacctt ggtctggcgc taaatttaat ctggtagaga
      121 ggtaagaaaa tggacgcttt aactagacga caatttgaca gagccatgtt tgccaaggaa
      181 aggacgctgg ctattcgtgt tggtgattat gcttcacggg atatcaaaga ggctagtttt
      241 gagtatggct acattaaggg cgatacttat aagcctggtg gaacctgcgc tggtagcggt
      301 aaaattacct ttaccagtat cattaccacg ttcaataagc tggataccct gcaccctgag
      361 attggtctac tggttgggga tacctaccag tgggtcaaga tgggggaata cttcatcaac
      421 gatattgaga ttgaccgaaa ccgaaacact accacgcttg aacttatgga cggtatgttt
      481 aagctcaatc gtgagtacgt gacggacttg catttcccag ctgaagtacg agaggttatt
      541 caggaaatct gcctgaaaac aggcattgag ttagcgaatg actatttcgg aatcagcgcg
      601 atgcgttatc atattgagca agttcctgag ggcaagaaac tttcctttag ggatatgctg
      661 agcgctatga ctcagatgat tgggatgtct tgtttcttca acagagaagg caagatggaa
      721 atccgtgatt tgactgagtc caatatcacg atcaacgctg acagttactt cttgcatggc
      781 ttgaccaaga gtgagattga gtatcagata tctggtatca cttgtaagac ggacaagaag
      841 tctctgacgg tcggtatgaa gacaggtcgg tctttggaac tggacaatgt cttcatgacc
      901 cagagcgctt taaatgacct gtattacaaa ctgaaaaacc taacttacta tccgtataat
      961 ctcaactacc aaggacattt gttacttgag gttgggcagt gggtaaccat tcagaccaac
     1021 aagaaagaga cttttaaagt tcccgtgtta agtcagagct ttacctttaa aggtggtctg
     1081 agaggtcgta tcagtgcaga tagtaaggct agaaacgata cccagtattc ttacgagggt
     1141 acgattacca agcagattaa gcaacaagat ggcattgaag cgaaaatcca agcgcagatt
     1201 gaagcagcag ataaagattt tgaccaaaag gtcgacaaaa tcaaaaaaga ctttaacgat
     1261 caagtagaac t
//
LOCUS       DAVDHC010000085         1180 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVDHC010000085 DAVDHC010000000
VERSION     DAVDHC010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1180
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.087"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..714
                     /locus_tag="VUR43_002273"
     CDS             <1..714
                     /locus_tag="VUR43_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5413877.1"
                     /translation="RTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYDLARQLFPCAK
                     IVLDRFHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDSRKLSDKRFYR
                     PTFRIHLTNKEILNKLLSYSEDLKHHYQLYQLYQLLLFHFQNKEPEKFFGLIEDNLKQ
                     VHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKR
                     IFIALNIKKERTKFVLSRA"
     gene            complement(916..>1180)
                     /locus_tag="VUR43_002274"
     CDS             complement(916..>1180)
                     /locus_tag="VUR43_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET5413878.1"
                     /translation="LNSNGAMVTGWLQNNGSWYYLNANGSMATGWVKDGDTWYYLEAS
                     GAMKASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
BASE COUNT          356 a          251 c          204 g          369 t
ORIGIN      
        1 agaacacaag ctatcattcg aaatcacttt cttcgctacg atagagttgt ccgatgtcgc
       61 gtcaaaatta ttactatgga tatgtttagc ccttactatg acttagctag acaacttttc
      121 ccgtgtgcta aaatcgtgtt ggatcgcttt cacattgtac aacatcttag ccgtgctatg
      181 agtcgtgtgc gtgttcaaat catgaatcaa ttggatcgaa agtctcatga atacaaggct
      241 atcaagcgct actggaaact cattcaacag gatagccgta aactgagtga taagcgattt
      301 tatcgtccta cttttcgtat acatttaacc aataaagaga ttttaaacaa gcttttgagt
      361 tattcggaag acttgaaaca ccactatcag ctctatcagc tctatcagct cttgcttttt
      421 cacttccaga ataaggaacc agagaaattt ttcgggctta ttgaggacaa tcttaagcag
      481 gttcatccta tttttcagac tgtctttaaa accttcctca aagataaaga aaagattgtc
      541 aacgcccttc aactacacta ttctaatgcc aaactggaag cgaccaataa tctcatcaaa
      601 cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa acggattttt
      661 atcgctttga atatcaaaaa agaaaggaca aaatttgtcc tttctcgagc ttagctgact
      721 tcaacccact acagttgaca aagagccaaa aaactccgta gtctctagcg ctataaatcc
      781 agctagagat tacagagtta ttctttagtc taaacttcct acaagggtat attatctact
      841 gaaaggatat ggtatttgta gggaatactt taaagagttc ttacaggaag tcagtattaa
      901 ctagttatat taggtttagt ttacccattc accattggca ttgactccat agccatctac
      961 agttgtgttg actgcaaggg cacctgagcc attgacatag taccatttat ctgatacttt
     1021 gaaccattgg cttgctttca tagcacctga tgcttcaaga tagtaccagg tatctccatc
     1081 tttcacccaa cctgttgcca ttgaaccgtt agcgtttagg tagtaccatg agccattgtt
     1141 ttggagccat cctgttacca tagcaccatt gctgtttagg
//
LOCUS       DAVDHC010000086         1106 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVDHC010000086 DAVDHC010000000
VERSION     DAVDHC010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1106
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.088"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(88..237)
                     /gene="blpO"
                     /locus_tag="VUR43_002275"
     CDS             complement(88..237)
                     /gene="blpO"
                     /locus_tag="VUR43_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET5413879.1"
                     /translation="MDTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(481..684)
                     /gene="blpN"
                     /locus_tag="VUR43_002276"
     CDS             complement(481..684)
                     /gene="blpN"
                     /locus_tag="VUR43_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET5413880.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(700..954)
                     /gene="blpM"
                     /locus_tag="VUR43_002277"
     CDS             complement(700..954)
                     /gene="blpM"
                     /locus_tag="VUR43_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET5413881.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
BASE COUNT          362 a          265 c          134 g          345 t
ORIGIN      
        1 ttgctgcata ggctacacct ccaagtatag ctccacctgc agcaccagtt acacctattc
       61 ctatagcaaa tggtcccaat agaaatgtca aaccgttgtt gcacacccat caattgcgcc
      121 atatgcaacc cctgctgcac aactaatttt tcttccccaa tcaatatctc caccttcaac
      181 gcaagcaagc atttcattat ccataacaga aaattgtgac atcatttttg tatccatata
      241 gtatatcact tttcagttac ggaacaagtt taatataaaa attatcaaaa aaacataagc
      301 aataaagaga aaaattaatt tatcatagat tagaaataat atgacaaaac aattcaatga
      361 tgttaattca atagtctttt gttttttatc ggagatactt atggatagat aaataagata
      421 ggtttgaaaa gcgaagagaa taataaagaa tatagccttc ataaaattta gctttcattt
      481 ttatgatgta gcggtatagg ctaaatatcc acaaaccact gctcctccaa ttcctcctat
      541 tgcagcgccc catggtccta gaagtctccc atatttcact ccacccgctg cacaacctaa
      601 agcagcaact acagctgctc ctccggaatt acctccataa acctcactca gcattgtttc
      661 atttatatta caataagtat tcatacaagt ctccttttgt taaaatccac ccgttgcccc
      721 tgttactcct gcccaaagag ccacaccaaa tttagctcct atgtatccac atgctcccat
      781 aaatggcgct ccaacaccac tcgcagcaca aatagctgtc cctaaccccc agccaccaaa
      841 agcagcacca ccaccttcta agacattagt ttgccaatta ttcttgcctc cttcaatact
      901 agataacata gttatatcca tttcatgaaa ttgttccata atttttgtat ccatgacaaa
      961 tactcttttt tatttttaat ttttgtcttg ttgtaacttt gacaagttta gtatatcatc
     1021 gttttttaaa atttttcatc cagattttga atagtcatcg aaacgtcttg aattgcaaaa
     1081 attacattag acttcctgca aaacta
//
LOCUS       DAVDHC010000087         1094 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVDHC010000087 DAVDHC010000000
VERSION     DAVDHC010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.089"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..931)
                     /gene="pspC"
                     /locus_tag="VUR43_002278"
     CDS             complement(<1..931)
                     /gene="pspC"
                     /locus_tag="VUR43_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     LPXTG-anchored form"
                     /protein_id="HET5413882.1"
                     /translation="MFKSNHERRMRYSIRKFSVGVASVAVASLFMGSVVHATEKEGST
                     QAATSFNRGNGSQAEQRGELDLERDKAMKAVSEYVGKMVRDAYVKSDRKRHKNTVALV
                     NQLGNIKNRYLNEIVHSTSKSQLQELMMKSQSEVDEAVSKFEKDSFSSSSSGSSTKPE
                     TPQPENPEHQKPTTPSPDTKPSPQPEGKKPSVPDINQEKEKAKLAVVTYMSKILDDIQ
                     KHHLQKEKHRQIVALIKELDELKKQALSEIDNVNTKVEIENTVHKIFADMDAVVTKFK
                     KGLTQDTPKEPGNKKPSAPKPGMQPSPQPEVKPQ"
BASE COUNT          258 a          212 c          198 g          426 t
ORIGIN      
        1 gctgcggttt aacctctggt tgaggacttg gttgcatacc tggttttgga gcagatggtt
       61 ttttgttacc tggttctttt ggtgtgtcct gagttaagcc ttttttgaat ttagtcacaa
      121 ctgcatccat gtctgcaaat atcttgtgga ctgtattttc aatttctact ttggtattta
      181 cattatcaat ttcagaaaga gcttgctttt taagctcatc aagctcctta ataagagcaa
      241 caatctgacg atgtttttct ttctgcagat gatgtttttg tatatcatct aaaatcttgc
      301 tcatgtaggt tactacagca agcttagctt tttctttttc ctgattaatg tctggtacgc
      361 ttggtttctt gccttctggt tgagggcttg gtttggtatc tggagatgga gttgttggtt
      421 tttgatgctc tggattttcc ggctgcggag tttctggttt agtggaggat cctgaacttg
      481 acgaagaaaa tgagtccttt tcaaatttag acacagcttc atctacttct gattgactct
      541 tcatcatcag ttcctgtagt tggctttttg aggttgaatg aactatttca ttcaaatacc
      601 tgttcttaat gtttcccaac tggttaacta gagctacagt atttttatgt cgttttctat
      661 ctgattttac ataggcatct ctcaccattt ttcctacata ttcactgacc gctttcattg
      721 ccttatctcg ttctaaatcg agttctccac gttgttctgc ctgacttcca tttcccctat
      781 taaaagaagt ggctgcttgg gtacttccct ctttctctgt cgcatgtaca acacttccca
      841 taaaaagact ggcaacagct acgctagcta ctcctacact aaatttacga atggaataac
      901 gcattcttcg ctcatgattt gatttaaaca tgtctatatt ctccataatt ttaattaact
      961 acagtatatc ctgctaatat gaattgtata tgaaatttgc tacattattt ggctctataa
     1021 tatttgtagt gggtaaatcc cctatggata ttatggagcc tattttgtgt agaaaaaaag
     1081 tcccatatga ccta
//
LOCUS       DAVDHC010000088         1008 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVDHC010000088 DAVDHC010000000
VERSION     DAVDHC010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.090"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..451)
                     /locus_tag="VUR43_002279"
     CDS             complement(<1..451)
                     /locus_tag="VUR43_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HET5413883.1"
                     /translation="MSQTYQIKQSDIVIDLPKTVGAGYGQFWRSRSLYRVVKGSRGSK
                     KSKTTALNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITVKATGQKILFRGLDDELKITSITVDIGSLCWAWFEEAYQIETED"
     gene            complement(429..929)
                     /locus_tag="VUR43_002280"
     CDS             complement(429..929)
                     /locus_tag="VUR43_002280"
                     /inference="COORDINATES: protein motif:HMM:NF015550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HET5413884.1"
                     /translation="MVKKNRNKRSREQVDEFGLNSRERNFADEYIANGNNATQAYLKI
                     YPTSGEANAANKGSAWVRKGEILNYIKIKTKERLDASGLKANDIIDRLIDIAFGRPIV
                     GYSKQTDKITGEVIKYIEYEGTAPIDEQIKALELLGKYLKLFTDKVEADVSGTVVFAN
                     ESDIPD"
BASE COUNT          280 a          237 c          162 g          329 t
ORIGIN      
        1 tgtcttcagt ctcaatttga tatgcttcct cgaaccatgc ccaacacaga ctaccgatat
       61 cgactgtaat agatgtaatt ttgagttcat catccaaacc acggaacagt attttttgac
      121 cagtcgcttt tacagttatt tcaggcaaag actcgttaaa tttaaacaaa tgagtcacac
      181 ccaacacatt acacgcccat ttaaaatctg tatatgtcga ttgtttgttg gtattcgaat
      241 atctacgaat gacaagcaag ttggcccagg gatacttcaa aagacggata acataattca
      301 aagcggttgt cttggacttc ttcgaaccgc gggaaccttt tacaacacga taaagacttc
      361 ttgagcgcca gaactgtccg tacccagctc ctactgtctt aggtaggtcg attacaatat
      421 cactttgttt aatctggtat gtctgactca tttgcaaaca ccaccgttcc agaaacgtca
      481 gcttctactt tgtcggtgaa taacttgaga tacttaccta acaattcaag agcctttatc
      541 tgctcgtcaa taggcgccgt accttcgtat tcaatgtact ttataacttc tcccgtgatt
      601 ttatctgtct gtttactata tccaacaatt ggacgaccaa aggcaatatc gataagacga
      661 tctataatgt cattagcttt caaccccgat gcatctagtc gttctttagt tttgattttg
      721 atgtagttta aaatctcacc ttttctaacc catgcactac ctttgttagc ggcattagct
      781 tcgccagatg ttggatatat tttcaaataa gcctgtgttg cattattgcc attagcgatg
      841 tactcatctg caaaattgcg ttcacggcta tttaaaccaa actcatcaac ttgttctctg
      901 cttcttttat tcctgttctt ctttacaatt ttccatcacc acctttcgaa taatcaaaaa
      961 aagccacacg atgtgcgacc ttcttgcaag gcgactacaa ccttgcgt
//
LOCUS       DAVDHC010000089          908 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVDHC010000089 DAVDHC010000000
VERSION     DAVDHC010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..908
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.091"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..486
                     /locus_tag="VUR43_002281"
     CDS             <1..486
                     /locus_tag="VUR43_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET5413885.1"
                     /translation="FHRKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEI
                     LNKLLSYSEDLKHHYQLLLFHFQNKEPEKFFELIEDNLKQVHPIFQTVFKTFLKDKEK
                     IINALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSR
                     A"
     gene            complement(620..707)
                     /locus_tag="VUR43_002282"
     tRNA            complement(620..707)
                     /locus_tag="VUR43_002282"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(671..673),aa:Ser,seq:gct)
     gene            complement(714..787)
                     /locus_tag="VUR43_002283"
     tRNA            complement(714..787)
                     /locus_tag="VUR43_002283"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(751..753),aa:Ile,seq:gat)
     gene            complement(823..893)
                     /locus_tag="VUR43_002284"
     tRNA            complement(823..893)
                     /locus_tag="VUR43_002284"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(859..861),aa:Gly,seq:tcc)
BASE COUNT          309 a          204 c          147 g          248 t
ORIGIN      
        1 tttcatcgaa aatcccatga atacaaggct atcaagcgct actggaagct catacaacag
       61 gatagtcgta aactgagtga taagcgattt tatcgtccta cttttcgtat gcacttaacc
      121 aataaagaga ttttaaacaa gcttttgagt tattcggaag acttgaaaca ccactatcag
      181 ctcttacttt ttcacttcca gaataaggaa ccagagaaat ttttcgaact tattgaggac
      241 aatcttaagc aggttcatcc tatttttcag actgtcttta aaaccttcct caaagataaa
      301 gaaaagatta ttaacgccct tcaactaccc tattctaatg ccaaactgga agcgaccaat
      361 aatctcatca aacttatcaa gcgcaatgcc tttggatttc ggaactttga aaacttcaaa
      421 aaacggattt tcatcgcttt gaacatcaaa aaagaaagga caaaatttgt cctttctcga
      481 gcttagcttt tcttcaaccc actacagttg acaaagagcc ataaaaataa cttcagatta
      541 gtaattcaat taagttttac ggatctgaag ttttattgtc tctaaaaaca aaaaagagag
      601 ttacaaactc tcattaaaac ggagaataag ggattcgaac ccttgcgcca gttacccgac
      661 ctaacgattt agcaaaccgt cctcttcagc ctcttgagta attctccaat taatgggcac
      721 gagtggactc gaaccaccga cctcacgctt atcaggcgtg cgctctaacc acctgagcta
      781 cgcgcccaag ttaaaaaact tggtaatttg aacaaagttc aaagcgggtg acgagaatcg
      841 aactcgcgac aacagcttgg aaggctgtag ttttaccact aaactacacc cgcataaata
      901 ctatcaat
//
LOCUS       DAVDHC010000090          904 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVDHC010000090 DAVDHC010000000
VERSION     DAVDHC010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.092"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            146..310
                     /locus_tag="VUR43_002285"
     CDS             146..310
                     /locus_tag="VUR43_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413886.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            307..711
                     /locus_tag="VUR43_002286"
     CDS             307..711
                     /locus_tag="VUR43_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET5413887.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK"
BASE COUNT          268 a          139 c          159 g          338 t
ORIGIN      
        1 atgcttgctt ttttaatttt tacaattcaa gaggttttga tgaccattta tgatttgagt
       61 gatccaaggt caaaataagt gctatactag cagtgtaaat gttcttgctc aactaagata
      121 aatcgcacat ttaggaggaa atcttatgaa gaaaaaaata ctgattattt tcgttctgta
      181 tctaatcatg tccatctttc tatatccgct tagggagagt gcttggtatc agctatttta
      241 taccatagcc tatgtgattg cagttatgat ctattttgct atcaataaaa agaaaggaga
      301 aaagaaatga aaacttttct tgctaaaaaa cggaacatct tccttgcgag attgttctta
      361 ggtcagttgc ccttgcttgt ttctacttat ctatttctat ctcgtcagtt tttaaatttt
      421 tccgtagttt tccaatttct tttagtagtt attaacttgg cttctatttt ggttactgtt
      481 tatctcacta gggaaatgag gataagagag tttgaagatg atgatttggt tagtcctaga
      541 accaatcaac ttatgttcat cggcttgaca ggttttatgt ctattatttg tttgtataga
      601 ggtatcacag caggagaatc ctaccaacaa ataatcgctt atattggcgc tgttctctgc
      661 ttaatcatca tgcttctgct catgtggggc ttgaagtatt ataaaaagta gagcttaatg
      721 aagtataaaa gaaaagggta agtgtttttg caatacttac ccttttataa tagattccct
      781 gcgaaacaaa atatggtata gtatagtaga ttgaaactag aatagtacgc ctctacttct
      841 aaaacattgt tagaaatcga tttgactgtc ctgatcgatt tatcctgttc ttatttcatt
      901 ttac
//
LOCUS       DAVDHC010000091          871 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVDHC010000091 DAVDHC010000000
VERSION     DAVDHC010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.094"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..681
                     /locus_tag="VUR43_002287"
     CDS             <1..681
                     /locus_tag="VUR43_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET5413888.1"
                     /translation="KCNEWLDGVDIKRYEDLYHTNPRRARIVCDGEWGVAEGLIYENV
                     TVKDFDKDELLRDSANKLCIGLDFGFTHDPTALCCSLINDTTKEIYVFDEAYKVGLIT
                     KEVAKMIKDKGYHRSQIIADSAESRLIEELRSEHGISRIKESRKGKDSIMAGVSKLQG
                     YAIYVHPDCKNIMDEFYSYCYQRDKEGNWLNKPEDKNNHLMDALRYSLQCIEGGKATV
                     RRRSDYGL"
BASE COUNT          288 a          139 c          212 g          232 t
ORIGIN      
        1 aaatgcaatg agtggcttga tggagtcgat atcaaacgct atgaggattt gtatcatacg
       61 aaccccagac gtgctagaat cgtttgtgat ggtgaatggg gagttgctga aggtttaatc
      121 tatgagaacg tgaccgtcaa ggatttcgat aaggatgaat tgctacgaga ttcagctaat
      181 aagttatgta tcggtcttga ctttggtttt actcacgatc caaccgcttt gtgttgttcg
      241 ttgataaatg atacgacgaa agagatttat gtctttgatg aggcgtataa agtcggattg
      301 ataaccaaag aagttgcgaa gatgataaag gacaaaggtt atcatcgctc acaaatcatt
      361 gctgatagcg cagagtcacg gctgattgaa gagctcaggt cagaacatgg catatctaga
      421 ataaaagaga gtcggaaagg taaggatagt attatggcag gtgtatcaaa attgcaagga
      481 tacgctattt atgtgcatcc agattgtaaa aacatcatgg atgaatttta tagttattgc
      541 taccagcgag ataaagaagg caactggttg aataaaccag aggataaaaa caaccacttg
      601 atggacgctt tgcgttacag ccttcaatgt atcgaaggtg ggaaagcaac cgtccgcaga
      661 cgttctgatt atggtctata gagaggaaag acatgtacca atatttaacc tatccacggg
      721 atggatatga tgagggttct ttgaagaaag acctgattta caaattgata acgatgcata
      781 acactgaaag ctcacatttg aagaagctta aaagctacta tttgggtgag catgctatct
      841 tagaacacat gagacgcaac gtgaacgcac c
//
LOCUS       DAVDHC010000092          866 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVDHC010000092 DAVDHC010000000
VERSION     DAVDHC010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.095"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            73..243
                     /locus_tag="VUR43_002288"
     CDS             73..243
                     /locus_tag="VUR43_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413889.1"
                     /translation="MSEYALYQGDVFITLGTLAEISKETGIAERMLKYYTFASTQRRN
                     PNGRAVVKIEVE"
     gene            246..311
                     /locus_tag="VUR43_002289"
                     /pseudo
     CDS             246..311
                     /locus_tag="VUR43_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315463.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            304..483
                     /locus_tag="VUR43_002290"
     CDS             304..483
                     /locus_tag="VUR43_002290"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413890.1"
                     /translation="MNKRQRKKKILNGLNKEERYHRTHCPVCDSEAGLFDRYFNTYGF
                     CSEYCGYEYYGISRL"
     gene            504..818
                     /locus_tag="VUR43_002291"
     CDS             504..818
                     /locus_tag="VUR43_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413891.1"
                     /translation="MTLFDEMQQLSSESHAKWFERYFEKYNLEQKLKTSAQKGYTGYL
                     INVWSVRDEYLRNRLGDERTLEALRELLGADFTVKYKLYLSKNIFTGQDFVSNKKIHI
                     TW"
BASE COUNT          326 a          130 c          184 g          226 t
ORIGIN      
        1 aaaagaaaaa cggccttgaa gacctgaaga aagcgcgcaa gaaccttgat tggctgattg
       61 aggagatgga acatgagtga atacgcgtta tatcaaggcg acgtgttcat aacattggga
      121 actcttgcgg aaatcagtaa agaaacaggt attgctgaaa ggatgttaaa gtattacact
      181 tttgcatcca cgcaaagaag aaatccaaat ggtagagctg tcgtaaagat cgaggtggag
      241 tgatggaaga tgaggaaatc ataggcaaca tctacgaaaa tccggagctt ttggaggtaa
      301 ctcatgaata aacgtcaacg caaaaagaaa attttgaacg gtctgaacaa agaagaaaga
      361 taccacagga cgcattgtcc tgtctgcgat agcgaagctg gtttattcga cagatatttt
      421 aatacgtacg gtttctgctc tgaatattgt ggttatgaat actatggaat ttcaagatta
      481 taaaataaag gattgaggtt aaaatgacat tatttgatga aatgcagcaa ttaagctcag
      541 aaagccacgc aaaatggttc gagcgatatt ttgagaaata taacctagaa caaaaactaa
      601 aaacttctgc tcaaaaaggt tatacaggtt atttaatcaa tgtttggtca gttagagacg
      661 aatatctcag gaatcgatta ggagatgaaa gaacgttgga agcgttaaga gaattattag
      721 gagctgactt tactgtcaaa tataagcttt atctatctaa aaatattttc actggacaag
      781 atttcgtttc taacaagaaa attcacatta cttggtaaaa caaaaaagcc aagacactct
      841 ctgtctcagc aataatctca ataata
//
LOCUS       DAVDHC010000093          866 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVDHC010000093 DAVDHC010000000
VERSION     DAVDHC010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.096"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..>866
                     /locus_tag="VUR43_002292"
     CDS             <1..>866
                     /locus_tag="VUR43_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HET5413892.1"
                     /translation="VESNFKQRADSLEAGVSRLTEGLRTKADISSLNVTAENIRQSVK
                     SLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKASKSELTQTAEELSSKIASVQ
                     VGGRNYIRGTKRMMLARGLWASGTFRPSGAGTAKTIDVLDSPATGFDKAIRLTSSNAR
                     DQIGIAQDGFYISQGTYTMSCWVKGRRGQKVKLQTYWQVNDNSGISPIFTLKDENWTK
                     LSFTSARNRAGVASIGYVYLVNADVGEYLDVLAPQLEDGSLATSSKEAPEDIEGQIST
                     VESTFKQRADSL"
BASE COUNT          266 a          173 c          223 g          204 t
ORIGIN      
        1 ggtcgaatcc aactttaaac agcgtgctga ttcactcgaa gctggtgtaa gccgtctgac
       61 tgaaggcctt agaaccaaag ccgatatcag ctcactcaat gtgactgctg aaaatatccg
      121 gcaatctgtg aagagtcttg agacagacac gcagaacaag ctaaatcaga agttgagtca
      181 ggctgaattt gaggtgcgag ccggctctat ccgtcaggaa atcctgaatg caaccaagga
      241 taaagccagc aagtcagaac tcacgcagac agctgaggag ctctctagta agatagcgag
      301 tgtgcaggtc gggggtagga attatatccg gggtacaaag cgcatgatgt tagccagagg
      361 attgtgggca tcaggtactt ttagaccgtc aggcgctggg acggcaaaga cgattgatgt
      421 attagacagt ccagcaactg gctttgataa agcgatacga ttgacctcaa gcaatgctag
      481 agaccaaata ggtattgctc aagatggatt ttatatctcg caaggcacat acacgatgtc
      541 ttgttgggtc aaaggcagaa gaggtcaaaa ggtcaagcta caaacttatt ggcaagtcaa
      601 tgataattcg ggtatttcgc ccatctttac attaaaggat gaaaattgga caaagctatc
      661 gtttactagc gctagaaata gggctggagt cgcatcaatt ggctatgtgt atctcgtaaa
      721 tgctgatgtc ggagaatatt tagatgttct tgcgccccag ctggaagacg gaagtttggc
      781 aacaagctca aaagaagctc ctgaagatat agaaggtcag atttcaacag ttgaatcgac
      841 cttcaaacag cgtgctgatt cactcg
//
LOCUS       DAVDHC010000094          817 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVDHC010000094 DAVDHC010000000
VERSION     DAVDHC010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..817
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.097"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..>817
                     /locus_tag="VUR43_002293"
     CDS             <1..>817
                     /locus_tag="VUR43_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HET5413893.1"
                     /translation="TAEELASKIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYTVTI
                     DSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVIISFYAKA
                     NKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKRTTNEWLFNFNQEGT
                     VWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANSLEAGVNRLTEGLRTKAD
                     ISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKA"
BASE COUNT          277 a          153 c          186 g          201 t
ORIGIN      
        1 acagctgagg agctagctag taagatagcg agtgtgcagg catccggtcg aaatctattc
       61 ttgaactcac tattcaagca ggatattcca aaaacaggaa tttggacaac gagtacatat
      121 acggttacta tcgatagcga aagtaagtat cttggacaca aggctcttaa aattataggt
      181 ctgaatccat ctggccgtga tggaggtaat cccaaggtta cttatccagc tctgggtcaa
      241 ttcgggaaag taattcccgg aagtacgact aatcaagatg taatcattag tttttatgct
      301 aaggcaaata aaaatggaat aatgctaaga tctcgattag ggaatatcgg atataaaact
      361 ggaaatgtga cattgtcgac agaaattaag cgatatgttg tccatattcc aaaaggttgg
      421 acaaacgaat ccaagcggac cacaaatgaa tggttgttca atttcaacca agaaggaacc
      481 gtttggattt ggatgccgaa gtttgaaata agcgatgtag atacttctta ttcagaagct
      541 cctgaagata tagaaggtca gatttcaaca gttgaatcga ccttcaaaca acgagccaac
      601 tcgctcgaag ctggtgtgaa tcgtctgact gaaggcctta gaactaaagc cgatatcagt
      661 tcactcaatg tgactgctga aaatatccgg caatctgtga agagccttga gacagacacg
      721 cagaacaagc taaatcagaa gttgagtcag gctgaatttg aggtgcgagc tggctctatc
      781 cgtcaagaaa tcctgaacgc aaccaaggat aaagcca
//
LOCUS       DAVDHC010000095          809 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVDHC010000095 DAVDHC010000000
VERSION     DAVDHC010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.098"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            81..419
                     /locus_tag="VUR43_002294"
     CDS             81..419
                     /locus_tag="VUR43_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413894.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            394..>809
                     /locus_tag="VUR43_002295"
     CDS             394..>809
                     /locus_tag="VUR43_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET5413895.1"
                     /translation="MSELLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPIGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPA"
BASE COUNT          257 a          156 c          210 g          186 t
ORIGIN      
        1 agtagtctac ggagaaaaag gcctgtctac gggtcttcta cagcgaatac gcatgcacag
       61 gctagcaagg gtggcaggtc atgtttttga agcagagtag actgaaacct tatccaatgc
      121 gacggtttga aaagactgtc actgaggaag gtgtcgcgaa agaagggtat gccaaggaag
      181 ctgagacagt ccgccttgaa ttgtggccag ctagtagcaa actacaatct gaattgtatg
      241 gcgagcgtgt caatgatatt ttgaacgcaa atgccaacaa atcagctact atcaaagtga
      301 aagatggtgt gtgtatcgat agccagacag aagtgactca cagggttatc tctaaaaagg
      361 tctacacaca tcatcaagtc ttggagttag agcgtgtcag agctactagg ggcagatagg
      421 cttatagcta aatgtagacg attggctagt aaaaaaactg gcgaggatat cgtcttacgt
      481 gcggtacaca atgctactat aaaggttgtc caagcagatg caagaagact cgcaccagcg
      541 agagatggag agcttataac tagtatcaaa actagggcaa aaatggacgg agataaggct
      601 ataggcgagg tttacaccaa cctaaaatac gctccttacg ttgagtttgg gacagggcca
      661 ataggacaag ctagccattc tggtatctct ccagaggtca gcgtaactta caagtctagt
      721 ccgtggtatg tgcatgaaga ccaaatcaat gtaggacctt accactttca aaagattggg
      781 gagttctaca agatgtatgg tcaacctgc
//
LOCUS       DAVDHC010000096          793 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVDHC010000096 DAVDHC010000000
VERSION     DAVDHC010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.099"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            105..584
                     /locus_tag="VUR43_002296"
     CDS             105..584
                     /locus_tag="VUR43_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET5413896.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VUR43_002297"
     tRNA            678..749
                     /locus_tag="VUR43_002297"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
BASE COUNT          291 a          110 c          185 g          207 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtttataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggc agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ttagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa aggctgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc gtcaggacca cttgataaaa
      781 aaagtttaaa aaa
//
LOCUS       DAVDHC010000097          692 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVDHC010000097 DAVDHC010000000
VERSION     DAVDHC010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.100"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VUR43_002298"
     tRNA            complement(74..147)
                     /locus_tag="VUR43_002298"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VUR43_002299"
     tRNA            complement(157..242)
                     /locus_tag="VUR43_002299"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VUR43_002300"
     tRNA            complement(250..321)
                     /locus_tag="VUR43_002300"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VUR43_002301"
     tRNA            complement(344..416)
                     /locus_tag="VUR43_002301"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VUR43_002302"
     tRNA            complement(435..516)
                     /locus_tag="VUR43_002302"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VUR43_002303"
     tRNA            complement(522..594)
                     /locus_tag="VUR43_002303"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VUR43_002304"
     tRNA            complement(619..691)
                     /locus_tag="VUR43_002304"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          204 c          149 g          160 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVDHC010000098          690 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVDHC010000098 DAVDHC010000000
VERSION     DAVDHC010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..690
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.101"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            58..270
                     /locus_tag="VUR43_002305"
     CDS             58..270
                     /locus_tag="VUR43_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000160160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413897.1"
                     /translation="MTKFVKIQSCYRGHTEDELINIDDIGRICLGPNILFLRTPYNLG
                     EHHISITQNSVDKLLKVLDIIGEDGK"
     gene            267..638
                     /locus_tag="VUR43_002306"
     CDS             267..638
                     /locus_tag="VUR43_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413898.1"
                     /translation="MRPCKYPFLGRRKKQETSSPLFSARPIFKEVPIVEEVKVEFEVE
                     ANVGRSYPVMIIHLDIYGYGNRVHSVYRFPGIFLTVGESIQLKILFYKRLRNFTADRF
                     LTFRESDWKFLISDLVNEFVR"
BASE COUNT          234 a           94 c          145 g          217 t
ORIGIN      
        1 gcaaagttcg gctgggtgtt tgattgtgaa ggaattgata tagaggaggt ggaataaatg
       61 acaaaatttg ttaaaataca atcttgttat agaggacata ctgaagatga gcttatcaac
      121 atagatgata ttgggcgcat ctgtctaggc cctaatatct tgtttttaag aacaccttac
      181 aatttaggag aacatcatat ttctatcact caaaattcag tagataaact tttgaaagta
      241 ttggatatta ttggggagga cggcaaatga gaccttgtaa atatccattt ttgggaagaa
      301 gaaaaaaaca agaaacatcg tcgccattat tttctgcacg accaattttt aaagaagttc
      361 caattgtaga agaagttaag gttgagttcg aagttgaagc taatgttgga cgttcatatc
      421 cagtaatgat aatacattta gatatttatg gatacggaaa tagagtgcat tcagtatatc
      481 gttttcctgg catcttcctg actgttggtg agtcaatcca gctaaagata ctcttttata
      541 aaaggcttag aaattttacc gcagatcgtt ttttgacctt tagagaatct gattggaagt
      601 tccttatcag cgatctggtc aacgaatttg tgcgttagaa agttaatgag gtgaaggaat
      661 gaacccagaa ataattgaca atgtaaataa
//
LOCUS       DAVDHC010000099          681 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVDHC010000099 DAVDHC010000000
VERSION     DAVDHC010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 681)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 681)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..681
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.102"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            21..290
                     /locus_tag="VUR43_002307"
     CDS             21..290
                     /locus_tag="VUR43_002307"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413899.1"
                     /translation="MIELIENNGLEIQSKKCYDPQSAWHGEELWIVDKKKQNKIFDLS
                     GNGYCFHDAKVEEAIEEVEKYLLLKKMDTFDDFKKWVEKNAKPKK"
     gene            431..643
                     /locus_tag="VUR43_002308"
     CDS             431..643
                     /locus_tag="VUR43_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413900.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDL
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
BASE COUNT          266 a           64 c          154 g          197 t
ORIGIN      
        1 tgatgaataa gtacaaaaag ttgatagaat tgattgaaaa taacggtctt gagatacaat
       61 ctaagaaatg ttatgatcca cagagtgctt ggcatggtga ggagttatgg attgttgata
      121 agaaaaaaca aaataaaatt tttgatttat caggtaacgg ttactgtttt catgacgcta
      181 aagttgagga agccattgaa gaagttgaga agtatctatt attgaaaaag atggatacgt
      241 ttgatgattt caaaaaatgg gtggaaaaga atgctaagcc taaaaaatga tgcttagaaa
      301 ggagtaaaga catgtttata tgggattggg tatcaatcgc ctttgggtgg ttggtatttt
      361 tgttgttaat atttattatt atggccgtaa tcagcggaat aattaaaggt gtaaagaaag
      421 gaacagaaaa atggaagaat ggaaagaaag atttaaaaaa gaatactacg aattgaaaga
      481 acgattccag aagttagata tgatgattgg gaaatacgaa aaagggcaac tagagtttga
      541 atctaaatgt ccgattgatt tgttaaaagg tcagcgttca accatgtgga attatttaag
      601 aattctagaa caacgtgcaa aaattgaaga aattaaacta taaaaattaa ccgcatcgaa
      661 atcgaggcgg ttttcttatg t
//
LOCUS       DAVDHC010000100          655 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVDHC010000100 DAVDHC010000000
VERSION     DAVDHC010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.103"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..71)
                     /gene="ffs"
                     /locus_tag="VUR43_002309"
     ncRNA           complement(<1..71)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VUR43_002309"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(104..571)
                     /locus_tag="VUR43_002310"
     CDS             complement(104..571)
                     /locus_tag="VUR43_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET5413901.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
BASE COUNT          183 a          190 c           89 g          193 t
ORIGIN      
        1 tcaaatcgct tagggctgct ggattcctcc cctgacccgc ttcacgcaga actgttgctc
       61 cactatttat tatatcacat tcctattcat tttaaaagca aaattatttt ttccgtctat
      121 ttctaaaaaa atcctgcatg atagctgcgc attcatcttc caaaattcct atttcaacct
      181 ccacacgatg attgagacgc tcatctgtca agatatcgta caaactccca gcagcgccaa
      241 atttctggtt tttagcccca tagaccacat ttggaatgcg ggcaagccca atcgccccac
      301 tacacatgac acaaggttca atggtcacaa aaagtgtgca atccagcaag cgccagctct
      361 cctcactcaa gttcgcatcc tctatagcca taatttccgc atgcataacc gctcgctgta
      421 attcctcacg cgcattatgc ccacgaccaa tgatttcccc atctttgaca atcacacaac
      481 caattggaat ttcatcgtgt tcaagagcaa tctcagcctc tctcaaagcc tccctcataa
      541 agacttcttt ttcttcaagc gtataataca tctcttttct cttttcctac ttatcgattt
      601 tattattata tcatgaatcc caacacaaaa gaagccaccg aatgcggtga ctcta
//
LOCUS       DAVDHC010000101          592 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVDHC010000101 DAVDHC010000000
VERSION     DAVDHC010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.104"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            250..592
                     /locus_tag="VUR43_002311"
                     /pseudo
     CDS             250..592
                     /locus_tag="VUR43_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
BASE COUNT          206 a           86 c          108 g          192 t
ORIGIN      
        1 ttatctacaa cctcaaaact gtgttttgag taacctgcgg ctagcttcct agtttgctct
       61 ttgattttca ttgagtatta gaacagaaaa atgcttggag tatttgtttg tgtgtttatt
      121 tttatataac aaactataaa caaaacaaaa atataaaaaa gagacaaaaa agaacagaaa
      181 gtaattaaca acgatttcat atagtgttat acttatagca taaagttaat ggaaagaagg
      241 gaaaacctta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg cttagaagcg
      301 gataatcaag aataactctt tgatcaggtt gcaactttat tggaagaacg agaaattgtc
      361 actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac tggtttatat
      421 atggaatttc taggaaagga cttgcaaatg taatgattcc tcacacagat attgttcata
      481 atctagctga gaaagtggtg gttgttcgat tagagaaacc ggtgactttc cataatatga
      541 ttgcgccagg taaggaagta gaagtatcct tgctcttctt tatcatcaat aa
//
LOCUS       DAVDHC010000102          538 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVDHC010000102 DAVDHC010000000
VERSION     DAVDHC010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..538
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.105"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            155..535
                     /locus_tag="VUR43_002312"
     CDS             155..535
                     /locus_tag="VUR43_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413902.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
BASE COUNT          185 a           91 c           95 g          167 t
ORIGIN      
        1 ggctatcgag ccgagggaaa agagggaata cttacaaccc aagtaactgt aaaagcttat
       61 gatgaagaca agcaaccgat taacttcgca aatttattag attccttaat cgtctcagaa
      121 tatcaaatgg aaccgaatct ttgggaggtc tctcatgatt gatctctatc taagtaaaaa
      181 tagccaaaga aatcaacttc ttttggattt ctttcaaaag tatggcatag aggtcactcc
      241 tcattctatt tctgaaatga caaaggacaa attaattgaa atgatgagct attcttcaga
      301 ttgttttgag tttttatctc ctaatttatt acgatttaag aaccgtgaca atctaagatt
      361 aacggatttc gttgagatga ttttaaaaaa tcctgaacta accatcagac ttcctcttgc
      421 ggtttcaaat aagcgggttt atccgaatct gaatttggaa gaggctagag ctttattgcc
      481 aagagatacg aaacaattga tttatatggc acaaacacat tatttatcta actaaagg
//
LOCUS       DAVDHC010000103          478 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVDHC010000103 DAVDHC010000000
VERSION     DAVDHC010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.106"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..>478
                     /locus_tag="VUR43_002313"
     CDS             <1..>478
                     /locus_tag="VUR43_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET5413903.1"
                     /translation="DLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDI
                     LAFLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYV
                     TPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRV"
BASE COUNT          155 a           95 c          109 g          119 t
ORIGIN      
        1 atgacttact agcaagaatt caccaagatt tacttgataa taaaggtcga caagttgatt
       61 ttgaggcttt ggataacctg ttggaacgac tcaaggatgt ctcaagtgat aaagtcaagt
      121 tagtggatga tattcttgcc ttcttagctc cgattcgtca tccagaacgt ttaggaaaac
      181 caaatgcgca aattacctac actgatgatg agattcaagt agccaagttg gcaggcaagt
      241 acacaacaga agacggttat atctttgatc ctcgtgatat aaccagtgat gagggggatg
      301 cctatgtaac tccacatatg acccatagcc actggattaa aaaagatagt ttgtctgaag
      361 ctgagagagc ggcagcccag gcttatgcta aagagaaagg tttgacccct ccttcgacag
      421 accatcagga ttcaggaaat actgaggcaa aaggagcaga agctatctac aaccgcgt
//
LOCUS       DAVDHC010000104          467 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVDHC010000104 DAVDHC010000000
VERSION     DAVDHC010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.107"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..>467)
                     /locus_tag="VUR43_002314"
     CDS             complement(<1..>467)
                     /locus_tag="VUR43_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413904.1"
                     /translation="RNLLKGTKELARYKPVSEYNGFKVIRTVAGATRYQDSYVERTVI
                     PTAGTEYIAIFYARASENDYPVRCHFYNPNTVVSSENSSGYKSRSSDGLSIIRLSTDW
                     QLCWVKWTQTATDQAKTVIIGRHGPQVGGKEGVWVEICAPAIFEGNLAGDWSPA"
BASE COUNT          112 a          120 c           97 g          138 t
ORIGIN      
        1 gctggtgacc agtcacctgc aagatttccc tcaaaaatgg caggggcgca gatttcaacc
       61 cataccccct ctttaccgcc tacttgaggg ccatggcggc caatgatgac cgtcttggct
      121 tgatctgttg cggtttgggt ccatttaacc cagcacaact gccagtctgt cgagagacgg
      181 ataatagaca agccatctga cgaccttgac ttatatccgc tgctgttttc tgatgataca
      241 accgtgttag gattgtaaaa atgacagcgc acaggatagt cattttcact ggctcgtgca
      301 taaaagatag ctatatactc tgtcccagcc gttggtataa cggttctttc cacatagcta
      361 tcctgatatc tagttgctcc tgcgactgtt ctgataactt taaaaccatt atattcacta
      421 accggcttgt atctcgcaag ctcttttgtg cctttcagca gatttct
//
LOCUS       DAVDHC010000105          461 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVDHC010000105 DAVDHC010000000
VERSION     DAVDHC010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.108"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..>461
                     /locus_tag="VUR43_002315"
     CDS             <1..>461
                     /locus_tag="VUR43_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413905.1"
                     /translation="PIGSWFGQRWADVTSALANIGAWFTDMFQKAWTGLTNIFSKLGS
                     WFGERWNDVTSALSKVASWFGDIFGKAFDAVKNAFSSIGDFFKGVWDTVKSIFVNAGQ
                     MVGEAVGGAFKSAVNAVLGTIENVVNGFIGMINGVLGVVRNLPGLGWVGSV"
BASE COUNT          119 a           74 c          132 g          136 t
ORIGIN      
        1 ccaatcggct catggttcgg acaacgttgg gcagatgtga ctagtgcgtt ggctaatatc
       61 ggggcatggt ttactgacat gttccaaaaa gcatggactg gcttaacaaa catctttagc
      121 aaactaggtt cttggtttgg cgagagatgg aacgatgtta caagtgcact ttccaaagta
      181 gcaagctggt ttggcgatat attcggaaaa gcttttgacg ctgttaaaaa tgcctttagc
      241 tctatcggag acttctttaa aggcgtttgg gatactgtca aaagtatctt cgttaatgct
      301 ggtcagatgg tcggcgaggc agtaggtgga gcgtttaaga gtgcggtcaa tgcggttctt
      361 ggaacgattg aaaatgtagt caatggcttc atcggaatga ttaatggagt tttaggcgtt
      421 gtcagaaact tacctggtct aggatgggtt ggtagtgtaa g
//
LOCUS       DAVDHC010000106          444 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVDHC010000106 DAVDHC010000000
VERSION     DAVDHC010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.109"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..>444
                     /locus_tag="VUR43_002316"
     CDS             <1..>444
                     /locus_tag="VUR43_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET5413906.1"
                     /translation="FGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAYGGN
                     GIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLVFLL
                     ELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVV"
BASE COUNT          156 a           63 c           80 g          145 t
ORIGIN      
        1 gtttggggat cctttaaata ataacaagaa atttgcagta aaaacgggac aacagtgttt
       61 taaattttca agtggaaaat ttcttgataa acatgataga gtttttgaag gttatcctgc
      121 ctatggtgga aatggcattg cttggaaaag tcgaaaatat ttaattgata atcctactat
      181 catcattggt cgtgtaggtg catattgtgg taatgtaaga actacccacg gtaaggtatg
      241 gataagtgac aatgctatat atataaaaga atttaagaat tccgatttca atcttgtatt
      301 tttattagaa ttaatgaaag taattgattt tagtaaattt gctgatttct caggtcaacc
      361 aaagataact caaaaaccat tagaaaatca gaaatatatc ctcccccctc tagccctcca
      421 aaatgagttc gcagactttg tagt
//
LOCUS       DAVDHC010000107          434 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVDHC010000107 DAVDHC010000000
VERSION     DAVDHC010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.110"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            <1..>434
                     /locus_tag="VUR43_002317"
     CDS             <1..>434
                     /locus_tag="VUR43_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET5413907.1"
                     /translation="ALDGNVAGKEKQALIDQFRANGTQTYSATVNVYGNKDGKPDLDN
                     IVATKKVTININGLISKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVNHVIPY
                     ELFAGDGMLTRLLLKASDKAPWSDNGDAKNPALSPLGENVKT"
BASE COUNT          149 a           99 c           92 g           94 t
ORIGIN      
        1 tagccttgga cggaaatgta gctggcaaag aaaaacaagc gctcattgac cagttccgag
       61 caaatggtac tcaaacttac agcgctacag tcaatgtcta tggtaacaaa gacggtaaac
      121 cagacttgga caacatcgta gcaactaaaa aagtcactat taacataaac ggtttaattt
      181 ctaaagaaac agttcaaaaa gccgttgcag acaacgttaa agacagtatc gatgttccag
      241 cagcctactt agaaaaagcc aagggtgaag gtccattcac agcaggtgtc aaccatgtga
      301 ttccatacga actcttcgca ggtgatggta tgttgactcg tctcttgctc aaggcatctg
      361 acaaggcacc atggtcagat aacggtgacg ctaaaaaccc agccctatct ccactaggtg
      421 aaaacgtgaa gacc
//
LOCUS       DAVDHC010000108          419 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVDHC010000108 DAVDHC010000000
VERSION     DAVDHC010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.111"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            59..419
                     /locus_tag="VUR43_002318"
                     /pseudo
     CDS             59..419
                     /locus_tag="VUR43_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          130 a           99 c           67 g          123 t
ORIGIN      
        1 gctttcaaat ttctaggctc aggctgaaac agtctcccag actgtttcac tcccgaatgc
       61 taaaatcgtg ttggatcgct ttcacattgt gcaacatctt agccgtgcta tgagtcgtgt
      121 gcgtgttcaa atcatgaatc agtttcatca aaaatcccat gaatacaagg ctatcaagcg
      181 ctactggaaa ctcattcaac aggatagccg taaactcagc gataaacatt tttatcgccc
      241 tacttttcgc atgcacttaa caaataaaga aattcttgac aagattttaa gctattcaga
      301 agacttgaaa caccactatc agctcttgct ttttcacttc cagaataagg aaccagagaa
      361 atttttcggg cttattgagg acaatcttaa gcccaaatca ttcatacctc tctcaacta
//
LOCUS       DAVDHC010000109          318 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVDHC010000109 DAVDHC010000000
VERSION     DAVDHC010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.denovo.114"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            complement(<1..285)
                     /locus_tag="VUR43_002319"
     CDS             complement(<1..285)
                     /locus_tag="VUR43_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET5413908.1"
                     /translation="MPIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMD
                     LHEQSKADSNRREERLMTHLEKTTTELTTITHTVGDIQKEMVRMNDRMEEI"
BASE COUNT           77 a           68 c           60 g          113 t
ORIGIN      
        1 gatttcttcc atgcggtcgt tcatgcgaac catttctttt tgaatgtctc cgaccgtgtg
       61 agtgattgtg gttaattctg tagtggtctt ttctaggtga gtcatcaaac gctcttctcg
      121 tctattagag tcggcctttg attgctcgtg caaatccata atcttcttct ctcgcttgtc
      181 cgaagtcttg ataagatatc gaatgataat aaaaaaaagc aagataaaca aaatcgccca
      241 agctacctga ctttgagcga ttttttcagc ttcttcaatt ggcatacaac ctcctattct
      301 ttaggtttta ccgttgga
//
LOCUS       DAVDHC010000110         1794 bp    DNA     linear   BCT 16-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain 27
            SAMEA3145683-rid19736703.guided.080, whole genome shotgun sequence.
ACCESSION   DAVDHC010000110 DAVDHC010000000
VERSION     DAVDHC010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA3145683
            Sequence Read Archive: ERR755382
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-OCT-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001930057.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001930057.1
            Genome Coverage       :: 240x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/14/2023 08:43:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,322
            CDSs (total)                      :: 2,285
            Genes (coding)                    :: 2,149
            CDSs (with protein)               :: 2,149
            Genes (RNA)                       :: 37
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (23S)
            partial rRNAs                     :: 1, 1 (5S, 16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 70 of 136
            Pseudo Genes (incomplete)         :: 59 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 28 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA3145683-rid19736703.guided.080"
                     /strain="27"
                     /db_xref="taxon:1313"
     gene            117..545
                     /locus_tag="VUR43_002320"
     CDS             117..545
                     /locus_tag="VUR43_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET5413909.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            603..1212
                     /locus_tag="VUR43_002321"
                     /pseudo
     CDS             603..1212
                     /locus_tag="VUR43_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
     gene            1494..1741
                     /locus_tag="VUR43_002322"
                     /pseudo
     CDS             1494..1741
                     /locus_tag="VUR43_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
BASE COUNT          677 a          222 c          348 g          547 t
ORIGIN      
        1 taagtataaa acatatgagc cttttgaaag cagtataaaa ttggtatcaa tcaatgagta
       61 acaaagtatc agcatgattc gaaacattta cttgtaattt gcggaggaac atcaatatgg
      121 atggaataac aaaagatttt ataaaaacgg ctaaactaat gaaacaatta tggccccaat
      181 tgaccgataa agaagctatt gatgaagtaa aaaaatatac gaatggcaaa aatactgcaa
      241 tctttactga agttgaaggt gacacaattg taggtctagc actatgttca ctcagatttg
      301 attatgttga aggttgtaaa tatagtcctg ttggattctt agaagggatt attgttgacg
      361 aggaatatcg tttaaaggat attgctaaaa atctctgtac aaaatgtgag gaatgggcga
      421 aaaataaagg atgtaaggaa tttgcaagtg actgtacttt aacgaatacg gattctataa
      481 gatttcatct caatattgga tttcaggagg caaatagaat tattcatttt aagaaaaaat
      541 tataatttag aaacgtgaat aaacttgttt aaactttatg tatctttaga aagtgtgtta
      601 acttgaaaga acaaattttt ttgatgggtg ggaatccccc aatgaagaaa tatagtattg
      661 ttgataaaat tgtattatca accaagatta aaagaattat catttttaca gtttttcgag
      721 aaaattggga accgtacatg aaaaagtaca cggaagtttt tcaaagtcaa tttcctaatc
      781 taaacattga ttacttgctc ctggacactg agcagattga tcttgatagc tatctagatg
      841 ctgacataat tatcatcggt ggtggaaata cggaaaaata tattgctaac ttatgttaat
      901 caggagttca aaagttatat cgatcatatg cttaataaag aggcaaaaat tataggattt
      961 tctgcaggag ccctactatt aggagaaaaa gtctatgtct cacctaatga taattcagat
     1021 catcagataa agataaaaaa tggattagga ctctttagtc agtttttaat tagtgtccat
     1081 tatgattcct ggaatgataa agcaaataag gatagagctg aagaactcgt taatgttccc
     1141 ataattccac taaatgatca ttcttgtctt gtattggata aacttggaaa catcatagag
     1201 aaaattgact aactttcata atgtaaaaat ggatctagga aataaaagtg tagacgaact
     1261 ggataggtta ctagtgaaaa ctgcaaaaag tgttgtaaag tgaatcggag tgtgcttgat
     1321 ggattttagt agtaagatag ccataaataa gggctggtca gatgataaaa aatattgtgt
     1381 gacagatcaa aatcagtaaa aatatttctt gcgtgtttct gataagtcga agttagatta
     1441 taaaaaaatt tgaatttgat atgatggaga aagtagcttc tcttggagtt ccgatgtgta
     1501 aaccaattag cattgaactc tgcgatgacg aagtacattc tttacacgaa tggatagacg
     1561 gaagagatgc aatagatagc attttagctt attcagaaaa ccaacaatac acatatggtg
     1621 tagaagcagg aaagatactt agaaagattc atacaattcc tgctacagaa gtttgtgaag
     1681 attgggaaat ttttttaatc taaaaattga tgataaaatc tccaacgaaa tgatatggta
     1741 agtccgaaac gctcagtgtg taagcttgtt gctaaaagcg taaaaacctt ggaa
//
